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Nasal polypectomy

Ruchi Srivastava, Neelam Wadhwa, Shikha Gupta, Urvashi Razdan
The nose is an uncommon site for head and neck paraganglioma. The diagnosis is seldom established pre-operatively; its rarity, infrequent functionality and often benign biologic outcome underlie this fact. We present one such case in a 60-year-old man who presented with right nasal obstruction and episodic epistaxis. Rhinoscopy revealed a fleshy polypoid mass arising from the anterior cartilaginous nasal septum. Imaging studies excluded extra-nasal extension. The tumor was highly vascular showing numerous variable sized, mostly thin walled branching blood vessels akin to stag-horn shape simulating a vascular neoplasm...
2016: Türk Patoloji Dergisi
Aaron Jamison, Kevin Crofts, Fiona Roberts, Maria Elena Gregory
This article reports a presentation of lacrimal sac rhinosporidiosis and informs the reader of this uncommon but important diagnosis. A 36-year-old man from Pakistan presented with a 3-month history of swelling at the nasal aspect of the left lower lid. This was associated with occasional crepitus and slight localised discomfort, but no epiphora. There was a palpable fullness near the left medial canthus associated with telecanthus but a normal sac washout and normal eye examination otherwise. Previous medical history included an ipsilateral nasal polypectomy and inferior meatal antrostomy around 10 years previously, whilst living in Pakistan...
October 2016: Orbit
Mohd Afiq Mohd Slim, David Dick, Keith Trimble, Gary McKee
Patients with cystic fibrosis (CF) are at increased risk of nasal polyps. We present the case of a 17-month-old Caucasian patient with CF who presented with hypertelorism causing cycloplegic astigmatism, right-sided mucoid discharge, snoring and noisy breathing. Imaging suggested bilateral mucoceles in the ethmoid sinuses. Intraoperatively, bilateral soft tissue masses were noted, and both posterior choanae were patent. Polypectomy and bilateral mega-antrostomies were performed. Histological examination revealed inflammatory nasal polyposis typical of CF...
2016: BMJ Case Reports
Dewey A Christmas, Joseph P Mirante, Eiji Yanagisawa
No abstract text is available yet for this article.
June 2016: Ear, Nose, & Throat Journal
Joshua M Levy, Jess C Mace, E Ritter Sansoni, Zachary M Soler, Timothy L Smith
BACKGROUND: Abnormal olfaction is common with chronic rhinosinusitis (CRS) and associates with various measures of sinonasal inflammation. The Brief Smell Identification Test (BSIT) has demonstrated improvements in abnormal olfactory detection following endoscopic sinus surgery (ESS), but olfaction remains understudied using this instrument. Discerning longitudinal, postoperative durability in olfaction is critical for patient counseling. METHODS: Adult participants with medically recalcitrant CRS were prospectively enrolled into a multi-institutional cohort study and observed for 18 months after ESS...
May 24, 2016: International Forum of Allergy & Rhinology
Seung-Kyu Chung, Gyehwan Jo, Yang Na
We used computational fluid dynamics to study the airflow characteristics in the ostiomeatal complex/middle turbinate of the human upper airway, where clinically relevant nasal polypoid changes occur (designated Regions A1-A4). We assessed six different flow rates representing one full period of respiration, based on realistic human respiration data, in an anatomically correct numerical model of a patient with a history of polypectomy. The simulation results showed that Regions A1-A4 were not correlated with the local stagnation points where a locally high level of wall pressure was achieved...
March 1, 2016: Computers in Biology and Medicine
Lisa Caulley, Andrea Lasso, Luke Rudmik, Shaun J Kilty
Endoscopic polypectomy in clinic (EPIC) has demonstrated substantial short-term improvement in patient reported quality of life measures and a pilot economic analysis of EPIC confirmed its cost-effectiveness in comparison to endoscopic sinus surgery. The purpose of this study was to evaluate if pre-treatment Sino Nasal Outcome Tests-22 (SNOT-22) score predicts response to EPIC treatment in parallel to the results found for endoscopic sinus surgery. Depending on the baseline SNOT-22 group the probability of achieving minimal clinically important difference was 75-100% post-EPIC...
January 23, 2016: Clinical Otolaryngology
Emily P S Lam, Harsha H Kariyawasam, Batika M J Rana, Stephen R Durham, Andrew N J McKenzie, Nicholas Powell, Nara Orban, Melissa Lennartz-Walker, Claire Hopkins, Sun Ying, Joanne Rimmer, Valerie J Lund, David J Cousins, Stephen J Till
BACKGROUND: Chronic rhinosinusitis with nasal polyposis (CRSwNP) in Western countries is characterized by eosinophilia, IgE production, and TH2 cytokine expression. Type 2 innate lymphoid cells from polyps produce IL-5 and IL-13 in response to IL-25 and IL-33, although the relevance of this axis to local mucosal T-cell responses is unknown. OBJECTIVE: We sought to investigate the role of the IL-25/IL-33 axis in local mucosal T-cell responses in patients with CRSwNP...
May 2016: Journal of Allergy and Clinical Immunology
Rickul Varshney, Jivianne T Lee
PURPOSE OF REVIEW: Chronic rhinosinusitis (CRS) affects millions of patients worldwide, with significant health and financial implications. There is an immense utilization of resources involved, including prescription medications and surgical interventions. With increased emphasis on sound resource allocation and patient convenience, recent years have witnessed significant expansion in office-based rhinologic procedures. The purpose of this review is to discuss new technologic innovations designed to facilitate treatment of sinonasal disease in the clinic setting...
February 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
Saisawat Chaiyasate, Kannika Roongrotwattanasiri, Jayanton Patumanond, Supranee Fooanant
Objective. To investigate the length of follow-up needed to detect recurrence of antrochoanal polyps. Methods. A retrospective investigation was performed on patients who had been operated on with a preoperative diagnosis of antrochoanal polyps in Chiang Mai University hospital from 2006 to 2012. Results and Discussion. Of the 38 cases of choanal polyps, 27 were adults (71%). The median age was 23.5, ranging from 7 to 64 years old. Eighteen patients were male (47.4%). The origin of choanal polyps was the maxillary antrum in 32 patients...
2015: International Journal of Otolaryngology
L Rudmik, K A Smith, S Kilty
OBJECTIVE: The purpose of this pilot economic evaluation was to assess the cost-effectiveness of the endoscopic polypectomy in the clinic (EPIC) procedure compared to formal endoscopic sinus surgery (ESS) for the treatment of select chronic rhinosinusitis (CRS) patients with nasal polyposis. DESIGN: Cost-effectiveness analysis using a Markov decision tree model with a 30-year time horizon. The two comparative treatment groups were as follows: (i) EPIC and (ii) ESS...
April 2016: Clinical Otolaryngology
Katherine N Cahill, Benjamin A Raby, Xiaobo Zhou, Feng Guo, Derek Thibault, Andreas Baccarelli, Hyang-Min Byun, Neil Bhattacharyya, John W Steinke, Joshua A Boyce, Tanya M Laidlaw
Recurrent, rapidly growing nasal polyps are hallmarks of aspirin-exacerbated respiratory disease (AERD), although the mechanisms of polyp growth have not been identified. Fibroblasts are intimately involved in tissue remodeling, and the growth of fibroblasts is suppressed by prostaglandin E2 (PGE2), which elicits antiproliferative effects mediated through the E prostanoid (EP)2 receptor. We now report that cultured fibroblasts from the nasal polyps of subjects with AERD resist this antiproliferative effect...
January 2016: American Journal of Respiratory Cell and Molecular Biology
Carl Philpott, Claire Hopkins, Sally Erskine, Nirmal Kumar, Alasdair Robertson, Amir Farboud, Shahzada Ahmed, Shahram Anari, Russell Cathcart, Hisham Khalil, Paul Jervis, Sean Carrie, Naveed Kara, Peter Prinsley, Robert Almeyda, Nicolas Mansell, Sankalp Sunkaraneni, Mahmoud Salam, Jaydip Ray, Jaan Panesaar, Jonathan Hobson, Allan Clark, Steve Morris
OBJECTIVES: The aim of this study was to investigate the surgical revision rate in patients with chronic rhinosinusitis (CRS) in the UK CRS Epidemiology Study (CRES). Previous evidence from National Sinonasal Audit showed that 1459 patients with CRS demonstrated a surgical revision rate 19.1% at 5 years, with highest rates seen in those with polyps (20.6%). SETTING: Thirty secondary care centres around the UK. PARTICIPANTS: A total of 221 controls and 1249 patients with CRS were recruited to the study including those with polyps (CRSwNPs), without polyps (CRSsNPs) and with allergic fungal rhinosinusitis (AFRS)...
2015: BMJ Open
N R Wooles, P R Bell, R Adair
No abstract text is available yet for this article.
October 2015: Clinical Otolaryngology
Roya Azadarmaki, William Westra, Sanjay Prasad
OBJECTIVE: The purpose of this study is to introduce and define a disease entity on a continuum of eosinophilic otitis media: eosinophilic mucin otomastoiditis and otopolyposis. METHODS: A case of a 66-year-old woman with complicated chronic otitis media is reported. A literature review of the National Library of Medicine's online database, with a focus on eosinophilic otitis media and eosinophilic mucin rhinosinusitis, was performed. RESULTS: The authors report the case of a 66-year-old woman with a history of asthma, chronic rhinosinusitis, nasal polyposis, and chronic otitis media who presented with allergic middle ear mucin and otic polyps...
September 2015: Annals of Otology, Rhinology, and Laryngology
P Asimakopoulos, I Hathorn, H Monaghan, A T Williams
BACKGROUND: There is no consensus as to whether all routine bilateral polypectomy specimens should be sent for formal histopathological diagnosis to exclude underlying neoplastic pathology. This study assessed the necessity for histopathological investigation as routine practice in cases of bilateral and unilateral nasal lesions by estimating the incidence of unexpected pathologies. It also evaluated the ability of computed tomography to predict histopathological diagnosis in patients with unilateral nasal lesions...
March 2015: Journal of Laryngology and Otology
C Xie, S Hampal, C Li
BACKGROUND: Nasal gliomas are congenital neurogenic tumours that are mostly diagnosed in the perinatal period. They occur in 1 in 20 000-40 000 live births. Cases reported in adulthood are rare and the management in adults is controversial. CASE REPORT: A 55-year-old female had an incidental diagnosis of nasal glioma after routine endoscopic sinus surgery and polypectomy. Post-operatively, there was symptomatic improvement, but it was complicated by a cerebrospinal fluid leak...
March 2015: Journal of Laryngology and Otology
S J Kilty
No abstract text is available yet for this article.
June 2015: Clinical Otolaryngology
Joanne Rimmer, Wytske Fokkens, Lee Yee Chong, Claire Hopkins
BACKGROUND: Nasal polyps cause nasal obstruction, discharge and reduction in or loss of sense of smell, but their aetiology is unknown. The management of chronic rhinosinusitis with nasal polyps, aimed at improving these symptoms, includes both surgical and medical treatments, but there is no universally accepted management protocol. OBJECTIVES: To assess the effectiveness of endonasal/endoscopic surgery versus medical treatment in chronic rhinosinusitis with nasal polyps...
2014: Cochrane Database of Systematic Reviews
Jeong Jin Park, Chang-Hoon Kim, Jeung-Gweon Lee, Hyung-Ju Cho
Von-Willebrand disease (VWD) is one of the platelet dysfunction disorders that results from a deficiency of Von-Willebrand factor, which is essential for hemostasis. VWD patients typically have normal laboratory results on screening for bleeding disorders. To suspect and diagnose VWD, a careful review of past medical history and laboratory tests is critical. A 59-year-old male patient presented with intractable nasal bleeding after nasal polypectomy. The bleeding was controlled by platelet transfusion, and he was later diagnosed with VWD...
2014: Case Reports in Otolaryngology
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