Read by QxMD icon Read

Nasal polypectomy

Silke Anna Theresa Weber, Renata Mizusaki Iyomasa, Camila de Castro Corrêa, Wellington Novais Mafra Florentino, Giesela Fleischer Ferrari
INTRODUCTION: Nasal polyposis is often found in patients with cystic fibrosis. OBJECTIVE: To assess the incidence of nasal polyposis, the response to medical treatment, recurrence and the need for surgical intervention in children and adolescents with cystic fibrosis during a three-year follow-up. METHODS: Clinical symptoms (pulmonary, pancreatic insufficiency, malnutrition, nasal obstruction), two positive sweat chloride tests, and genotype findings in 23 patients with cystic fibrosis were analyzed...
October 17, 2016: Brazilian Journal of Otorhinolaryngology
Garima Singh, Meeta Singh, Mansi Chandana, Sompal Singh, Namrata Nargotra
Inverted Papilloma (IP) is an uncommon and locally aggressive benign tumour of sinonasal region, which tends to recur after surgical resection. Most tumours are confined to the lateral nasal wall and sinuses, with maxillary sinus being most commonly affected and a male preponderance. It has a known association with in situ and invasive carcinomas with a <10% rate of malignant transformation. Most common association has been seen with squamous cell carcinoma and extremely rare association with adenocarcinoma and small cell carcinoma...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
Vedat Yildirim, Niels Christian Pausch, Dirk Halama, Heinz-Theo Lübbers, Ayhan Yildirim
BACKGROUND: Sinonasal inverted papilloma is a locally aggressive tumor arising from the Schneiderian membrane which lines the nasal cavity and paranasal sinuses. Aggressive surgical approaches, such as lateral rhinotomy, were used until recently for complete removal of the inverted papilloma. Currently, endoscopic resection is the gold standard in the treatment of inverted papilloma. However, there are situations that justify an open approach. For example there are studies that report a higher postoperative recurrence rate after endonasal endoscopic resection, particularly in the treatment of recurrent diseases...
December 1, 2016: Journal of Medical Case Reports
Adam S DeConde, Jess C Mace, Joshua M Levy, Luke Rudmik, Jeremiah A Alt, Timothy L Smith
OBJECTIVES/HYPOTHESIS: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a disease process that is driven, in part, by intrinsic mucosal inflammation. Surgery plus continued medical therapy is commonly elected by medically recalcitrant, symptomatic patients. The objective was to evaluate the prevalence of nasal polyp recurrence up to 18 months after endoscopic sinus surgery (ESS) with congruent continuing medical management. STUDY DESIGN: Prospective, multicenter cohort of adult patients undergoing ESS for medically recalcitrant CRSwNP performed between August 2004 and February 2015...
March 2017: Laryngoscope
Ruchi Srivastava, Neelam Wadhwa, Shikha Gupta, Urvashi Razdan
The nose is an uncommon site for head and neck paraganglioma. The diagnosis is seldom established pre-operatively; its rarity, infrequent functionality and often benign biologic outcome underlie this fact. We present one such case in a 60-year-old man who presented with right nasal obstruction and episodic epistaxis. Rhinoscopy revealed a fleshy polypoid mass arising from the anterior cartilaginous nasal septum. Imaging studies excluded extra-nasal extension. The tumor was highly vascular showing numerous variable sized, mostly thin walled branching blood vessels akin to stag-horn shape simulating a vascular neoplasm...
2016: Türk Patoloji Dergisi
Aaron Jamison, Kevin Crofts, Fiona Roberts, Maria Elena Gregory
This article reports a presentation of lacrimal sac rhinosporidiosis and informs the reader of this uncommon but important diagnosis. A 36-year-old man from Pakistan presented with a 3-month history of swelling at the nasal aspect of the left lower lid. This was associated with occasional crepitus and slight localised discomfort, but no epiphora. There was a palpable fullness near the left medial canthus associated with telecanthus but a normal sac washout and normal eye examination otherwise. Previous medical history included an ipsilateral nasal polypectomy and inferior meatal antrostomy around 10 years previously, whilst living in Pakistan...
October 2016: Orbit
Mohd Afiq Mohd Slim, David Dick, Keith Trimble, Gary McKee
Patients with cystic fibrosis (CF) are at increased risk of nasal polyps. We present the case of a 17-month-old Caucasian patient with CF who presented with hypertelorism causing cycloplegic astigmatism, right-sided mucoid discharge, snoring and noisy breathing. Imaging suggested bilateral mucoceles in the ethmoid sinuses. Intraoperatively, bilateral soft tissue masses were noted, and both posterior choanae were patent. Polypectomy and bilateral mega-antrostomies were performed. Histological examination revealed inflammatory nasal polyposis typical of CF...
June 21, 2016: BMJ Case Reports
Dewey A Christmas, Joseph P Mirante, Eiji Yanagisawa
No abstract text is available yet for this article.
June 2016: Ear, Nose, & Throat Journal
Joshua M Levy, Jess C Mace, E Ritter Sansoni, Zachary M Soler, Timothy L Smith
BACKGROUND: Abnormal olfaction is common with chronic rhinosinusitis (CRS) and associates with various measures of sinonasal inflammation. The Brief Smell Identification Test (BSIT) has demonstrated improvements in abnormal olfactory detection following endoscopic sinus surgery (ESS), but olfaction remains understudied using this instrument. Discerning longitudinal, postoperative durability in olfaction is critical for patient counseling. METHODS: Adult participants with medically recalcitrant CRS were prospectively enrolled into a multi-institutional cohort study and observed for 18 months after ESS...
November 2016: International Forum of Allergy & Rhinology
Seung-Kyu Chung, Gyehwan Jo, Yang Na
We used computational fluid dynamics to study the airflow characteristics in the ostiomeatal complex/middle turbinate of the human upper airway, where clinically relevant nasal polypoid changes occur (designated Regions A1-A4). We assessed six different flow rates representing one full period of respiration, based on realistic human respiration data, in an anatomically correct numerical model of a patient with a history of polypectomy. The simulation results showed that Regions A1-A4 were not correlated with the local stagnation points where a locally high level of wall pressure was achieved...
March 1, 2016: Computers in Biology and Medicine
Lisa Caulley, Andrea Lasso, Luke Rudmik, Shaun J Kilty
Endoscopic polypectomy in clinic (EPIC) has demonstrated substantial short-term improvement in patient reported quality of life measures and a pilot economic analysis of EPIC confirmed its cost-effectiveness in comparison to endoscopic sinus surgery. The purpose of this study was to evaluate if pre-treatment Sino Nasal Outcome Tests-22 (SNOT-22) score predicts response to EPIC treatment in parallel to the results found for endoscopic sinus surgery. Depending on the baseline SNOT-22 group the probability of achieving minimal clinically important difference was 75-100% post-EPIC...
January 23, 2016: Clinical Otolaryngology
Emily P S Lam, Harsha H Kariyawasam, Batika M J Rana, Stephen R Durham, Andrew N J McKenzie, Nicholas Powell, Nara Orban, Melissa Lennartz-Walker, Claire Hopkins, Sun Ying, Joanne Rimmer, Valerie J Lund, David J Cousins, Stephen J Till
BACKGROUND: Chronic rhinosinusitis with nasal polyposis (CRSwNP) in Western countries is characterized by eosinophilia, IgE production, and TH2 cytokine expression. Type 2 innate lymphoid cells from polyps produce IL-5 and IL-13 in response to IL-25 and IL-33, although the relevance of this axis to local mucosal T-cell responses is unknown. OBJECTIVE: We sought to investigate the role of the IL-25/IL-33 axis in local mucosal T-cell responses in patients with CRSwNP...
May 2016: Journal of Allergy and Clinical Immunology
Rickul Varshney, Jivianne T Lee
PURPOSE OF REVIEW: Chronic rhinosinusitis (CRS) affects millions of patients worldwide, with significant health and financial implications. There is an immense utilization of resources involved, including prescription medications and surgical interventions. With increased emphasis on sound resource allocation and patient convenience, recent years have witnessed significant expansion in office-based rhinologic procedures. The purpose of this review is to discuss new technologic innovations designed to facilitate treatment of sinonasal disease in the clinic setting...
February 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
Saisawat Chaiyasate, Kannika Roongrotwattanasiri, Jayanton Patumanond, Supranee Fooanant
Objective. To investigate the length of follow-up needed to detect recurrence of antrochoanal polyps. Methods. A retrospective investigation was performed on patients who had been operated on with a preoperative diagnosis of antrochoanal polyps in Chiang Mai University hospital from 2006 to 2012. Results and Discussion. Of the 38 cases of choanal polyps, 27 were adults (71%). The median age was 23.5, ranging from 7 to 64 years old. Eighteen patients were male (47.4%). The origin of choanal polyps was the maxillary antrum in 32 patients...
2015: International Journal of Otolaryngology
L Rudmik, K A Smith, S Kilty
OBJECTIVE: The purpose of this pilot economic evaluation was to assess the cost-effectiveness of the endoscopic polypectomy in the clinic (EPIC) procedure compared to formal endoscopic sinus surgery (ESS) for the treatment of select chronic rhinosinusitis (CRS) patients with nasal polyposis. DESIGN: Cost-effectiveness analysis using a Markov decision tree model with a 30-year time horizon. The two comparative treatment groups were as follows: (i) EPIC and (ii) ESS...
April 2016: Clinical Otolaryngology
Katherine N Cahill, Benjamin A Raby, Xiaobo Zhou, Feng Guo, Derek Thibault, Andreas Baccarelli, Hyang-Min Byun, Neil Bhattacharyya, John W Steinke, Joshua A Boyce, Tanya M Laidlaw
Recurrent, rapidly growing nasal polyps are hallmarks of aspirin-exacerbated respiratory disease (AERD), although the mechanisms of polyp growth have not been identified. Fibroblasts are intimately involved in tissue remodeling, and the growth of fibroblasts is suppressed by prostaglandin E2 (PGE2), which elicits antiproliferative effects mediated through the E prostanoid (EP)2 receptor. We now report that cultured fibroblasts from the nasal polyps of subjects with AERD resist this antiproliferative effect...
January 2016: American Journal of Respiratory Cell and Molecular Biology
Carl Philpott, Claire Hopkins, Sally Erskine, Nirmal Kumar, Alasdair Robertson, Amir Farboud, Shahzada Ahmed, Shahram Anari, Russell Cathcart, Hisham Khalil, Paul Jervis, Sean Carrie, Naveed Kara, Peter Prinsley, Robert Almeyda, Nicolas Mansell, Sankalp Sunkaraneni, Mahmoud Salam, Jaydip Ray, Jaan Panesaar, Jonathan Hobson, Allan Clark, Steve Morris
OBJECTIVES: The aim of this study was to investigate the surgical revision rate in patients with chronic rhinosinusitis (CRS) in the UK CRS Epidemiology Study (CRES). Previous evidence from National Sinonasal Audit showed that 1459 patients with CRS demonstrated a surgical revision rate 19.1% at 5 years, with highest rates seen in those with polyps (20.6%). SETTING: Thirty secondary care centres around the UK. PARTICIPANTS: A total of 221 controls and 1249 patients with CRS were recruited to the study including those with polyps (CRSwNPs), without polyps (CRSsNPs) and with allergic fungal rhinosinusitis (AFRS)...
April 29, 2015: BMJ Open
N R Wooles, P R Bell, R Adair
No abstract text is available yet for this article.
October 2015: Clinical Otolaryngology
Roya Azadarmaki, William Westra, Sanjay Prasad
OBJECTIVE: The purpose of this study is to introduce and define a disease entity on a continuum of eosinophilic otitis media: eosinophilic mucin otomastoiditis and otopolyposis. METHODS: A case of a 66-year-old woman with complicated chronic otitis media is reported. A literature review of the National Library of Medicine's online database, with a focus on eosinophilic otitis media and eosinophilic mucin rhinosinusitis, was performed. RESULTS: The authors report the case of a 66-year-old woman with a history of asthma, chronic rhinosinusitis, nasal polyposis, and chronic otitis media who presented with allergic middle ear mucin and otic polyps...
September 2015: Annals of Otology, Rhinology, and Laryngology
P Asimakopoulos, I Hathorn, H Monaghan, A T Williams
BACKGROUND: There is no consensus as to whether all routine bilateral polypectomy specimens should be sent for formal histopathological diagnosis to exclude underlying neoplastic pathology. This study assessed the necessity for histopathological investigation as routine practice in cases of bilateral and unilateral nasal lesions by estimating the incidence of unexpected pathologies. It also evaluated the ability of computed tomography to predict histopathological diagnosis in patients with unilateral nasal lesions...
March 2015: Journal of Laryngology and Otology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"