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https://www.readbyqxmd.com/read/29350687/intraocular-currents-bernoulli-s-principle-and-non-drainage-scleral-buckling-for-rhegmatogenous-retinal-detachment
#1
D Wong, Y K Chan, T Bek, I Wilson, E Stefánsson
For many years, it is not fully understood how non-drainage scleral buckling surgery brings about spontaneous reattachment of the detached retina when retinal breaks remain open at the end of surgery. Various explanations have been put forward, but none more interesting than the effect of fluid currents associated with eye movements. One such explanation involved the physics of the Bernoulli's principle. Daniel Bernoulli was an eighteenth century Swiss mathematician and he described an equation based on the conservation of energy...
January 19, 2018: Eye
https://www.readbyqxmd.com/read/29349662/roles-and-maturation-of-iron-sulfur-proteins-in-plastids
#2
REVIEW
Jonathan Przybyla-Toscano, Mélanie Roland, Frédéric Gaymard, Jérémy Couturier, Nicolas Rouhier
One reason why iron is an essential element for most organisms is its presence in prosthetic groups such as hemes or iron-sulfur (Fe-S) clusters, which are notably required for electron transfer reactions. As an organelle with an intense metabolism in plants, chloroplast relies on many Fe-S proteins. This includes those present in the electron transfer chain which will be, in fact, essential for most other metabolic processes occurring in chloroplasts, e.g., carbon fixation, nitrogen and sulfur assimilation, pigment, amino acid, and vitamin biosynthetic pathways to cite only a few examples...
January 18, 2018: Journal of Biological Inorganic Chemistry: JBIC
https://www.readbyqxmd.com/read/29348535/umbilical-cord-extracts-improve-osteoporotic-abnormalities-of-bone-marrow-derived-mesenchymal-stem-cells-and-promote-their-therapeutic-effects-on-ovariectomised-rats
#3
Akira Saito, Kanna Nagaishi, Kousuke Iba, Yuka Mizue, Takako Chikenji, Miho Otani, Masako Nakano, Kazusa Oyama, Toshihiko Yamashita, Mineko Fujimiya
Bone marrow-derived mesenchymal stem cells (BM-MSCs) are the most valuable source of autologous cells for transplantation and tissue regeneration to treat osteoporosis. Although BM-MSCs are the primary cells responsible for maintaining bone metabolism and homeostasis, their regenerative ability may be attenuated in postmenopausal osteoporosis patients. Therefore, we first examined potential abnormalities of BM-MSCs in an oestrogen-deficient rat model constructed by ovariectomy (OVX-MSCs). Cell proliferation, mobilisation, and regulation of osteoclasts were downregulated in OVX-MSCs...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343897/contralateral-lumbo-umbilical-flap-a-versatile-technique-for-volar-finger-coverage
#4
Akram Hussain Bijli, Sheikh Adil Bashir, Altaf Rasool, Mir Yasir, Adil Hafeez Wani, Tanveer Ahmad, Mushtaq Ahmad
Background: While contemplating any difficult soft tissue reconstruction, patient comfort and compliance is of paramount importance. Reconstruction of the volar aspect of fingers and hand by the ipsilateral pedicled flaps (groin flap, abdominal flaps) is demanding as the flap inset is difficult for the surgeon and very uncomfortable for the patient. This often leads to flap complications. For the comfort of the patient, better compliance and ease of complete inset, we planned to manage soft tissue defects of the volar aspect of fingers and hand by a new contralateral pedicled lumbo-umbilical flap...
May 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29332737/effect-of-a-lateral-glide-mobilisation-with-movement-of-the-hip-on-vibration-threshold-in-healthy-volunteers
#5
Darren A Smith, Jacob Saranga, Andrew Pritchard, Nikolaos A Kommatas, Shinu Kovelal Punnoose, Supriya Tukaram Kale
BACKGROUND: Mulligan's mobilisation-with-movement (MWM) techniques are proposed to achieve their clinical benefit via neurophysiological mechanisms. However, previous research has focussed on responses in the sympathetic nervous system only, and is not conclusive. An alternative measure of neurophysiological response to MWM is required to support or refute this mechanism of action. Recently, vibration threshold (VT) has been used to quantify changes in the sensory nervous system in patients experiencing musculoskeletal pain...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332647/social-support-a-key-factor-for-adherence-to-multidrug-resistant-tuberculosis-treatment
#6
R D Deshmukh, D J Dhande, K S Sachdeva, A N Sreenivas, A M V Kumar, M Parmar
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is emerging as a major public health problem globally. Treatment success rates in MDR-TB across the globe are not encouraging as completing MDR-TB treatment successfully is challenging due to high proportion of lost to follow up. METHODS: Using qualitative methods and grounded theory approach, in-depth interviews were conducted with MDR-TB patients and treatment providers. The social cognitive framework was explored as a way to guide understanding of the factors affecting treatment adherence among MDR-TB patients...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29331268/the-population-biology-and-transmission-dynamics-of-loa-loa
#7
REVIEW
Charles Whittaker, Martin Walker, Sébastien D S Pion, Cédric B Chesnais, Michel Boussinesq, María-Gloria Basáñez
Endemic to Central Africa, loiasis - or African eye worm (caused by the filarial nematode Loa loa) - affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of public health relevance because it impedes mass drug administration-based interventions against onchocerciasis and lymphatic filariasis in co-endemic areas. Recent research has challenged this conception, demonstrating excess mortality associated with high levels of infection, implying that loiasis warrants attention as an intrinsic public health problem...
January 10, 2018: Trends in Parasitology
https://www.readbyqxmd.com/read/29330390/freezing-the-graft-is-not-necessary-for-autotransplants-for-plasma-cell-myeloma-and-lymphomas
#8
Amado Kardduss-Urueta, Robert Peter Gale, César H Gutierrez-Aguirre, Miguel Angel Herrera-Rojas, Iván Murrieta-Álvarez, Rosendo Perez-Fontalvo, Guillermo J Ruiz-Delgado, Giovanni Ruiz-Rojas, Gregorio Jaimovich, Leonardo Feldman, Nancy Labastida-Mercado, Alicia Endara, Martín Castro, Samantha Galindo-Becerra, María Angélica Cardona-Molina, David Gomez-Almaguer, Guillermo J Ruiz-Argüelles
We studied rates of granulocyte and platelets recovery in 359 consecutive subjects receiving blood cell infusions in the context of autotransplants for plasma cell myeloma (N = 216) and lymphomas (N = 143). Blood cells were mobilised with filgrastim given for 4-5 days and collected after a median of 2 (range, 1-2) apheresis. Apheresis products were stored at 4° C for a median of 3 days (range, 2-6 days). Most subjects received carmustine, etoposide, cytarabine and melphalan (BEAM), cyclophosphamide, carmustine and etoposide (CBV) or high-dose melphalan...
January 12, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/29325025/towards-an-understanding-of-resilience-responding-to-health-systems-shocks
#9
Johanna Hanefeld, Susannah Mayhew, Helena Legido-Quigley, Frederick Martineau, Marina Karanikolos, Karl Blanchet, Marco Liverani, Esther Yei Mokuwa, Gillian McKay, Dina Balabanova
The recent outbreak of Ebola Virus Disease (EVD) in West Africa has drawn attention to the role and responsiveness of health systems in the face of shock. It brought into sharp focus the idea that health systems need not only to be stronger but also more 'resilient'. In this article, we argue that responding to shocks is an important aspect of resilience, examining the health system behaviour in the face of four types of contemporary shocks: the financial crisis in Europe from 2008 onwards; climate change disasters; the EVD outbreak in West Africa 2013-16; and the recent refugee and migration crisis in Europe...
January 9, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29322613/forward-view-advancing-health-library-and-knowledge-services-in-england
#10
Sue Lacey Bryant, Helen Bingham, Ruth Carlyle, Alison Day, Linda Ferguson, David Stewart
This article is the fourth in a series on New Directions. The National Health Service is under pressure, challenged to meet the needs of an ageing population, whilst striving to improve standards and ensure decision making is underpinned by evidence. Health Education England is steering a new course for NHS library and knowledge services in England to ensure access to knowledge and evidence for all decision makers. Knowledge for Healthcare calls for service transformation, role redesign, greater coordination and collaboration...
January 10, 2018: Health Information and Libraries Journal
https://www.readbyqxmd.com/read/29321920/impact-of-medial-to-lateral-vs-lateral-to-medial-approach-on-short-term-and-cancer-related-outcomes-in-laparoscopic-colorectal-surgery-a-retrospective-cohort-study
#11
Anwar Hussain, Fahad Mahmood, Andrew W Torrance, Achilleas Tsiamis
Background: Laparoscopic surgery is the favoured method of colorectal cancer resections. It is surgeon expertise and discretion to choose whether to mobilize colon lateral-to-medial or medial-to-lateral. We aim to identify the advantage of one approach over the other in short-term and cancerrelated outcomes. Methods: A retrospective review of a prospectively maintained database of all laparoscopic colorectal resections with curative-intent, in a single unit, from March 2013 to October 2014...
February 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29318985/a-randomised-controlled-trial-and-economic-evaluation-of-intraoperative-cell-salvage-during-caesarean-section-in-women-at-risk-of-haemorrhage-the-salvo-cell-salvage-in-obstetrics-trial
#12
Khalid S Khan, Philip Moore, Matthew Wilson, Richard Hooper, Shubha Allard, Ian Wrench, Tracy Roberts, Carol McLoughlin, Lee Beresford, James Geoghegan, Jane Daniels, Sue Catling, Vicki A Clark, Paul Ayuk, Stephen Robson, Fang Gao-Smith, Matthew Hogg, Louise Jackson, Doris Lanz, Julie Dodds
BACKGROUND: Caesarean section is associated with blood loss and maternal morbidity. Excessive blood loss requires transfusion of donor (allogeneic) blood, which is a finite resource. Cell salvage returns blood lost during surgery to the mother. It may avoid the need for donor blood transfusion, but reliable evidence of its effects is lacking. OBJECTIVES: To determine if routine use of cell salvage during caesarean section in mothers at risk of haemorrhage reduces the rates of blood transfusion and postpartum maternal morbidity, and is cost-effective, in comparison with standard practice without routine salvage use...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29318981/magnesium-homeostasis-in-cattle-absorption-and-excretion
#13
Holger Martens, Sabine Leonhard-Marek, Monika Röntgen, Friederike Stumpff
Magnesium (Mg2+) is an essential mineral without known specific regulatory mechanisms. In ruminants, plasma Mg2+ concentration depends primarily on the balance between Mg2+ absorption and Mg2+ excretion. The primary site of Mg2+ absorption is the rumen, where Mg2+ is apically absorbed by both potential-dependent and potential-independent uptake mechanisms, reflecting involvement of ion channels and electroneutral transporters, respectively. Transport is energised in a secondary active manner by a basolateral Na+/Mg2+ exchanger...
January 10, 2018: Nutrition Research Reviews
https://www.readbyqxmd.com/read/29318337/full-endoscopic-posterior-foraminotomy-surgery-for-cervical-disc-herniations
#14
REVIEW
M Komp, S Oezdemir, P Hahn, S Ruetten
OBJECTIVE: Surgery for cervical disc herniation with full-endoscopic posterior access. INDICATIONS: Cervical disc herniation and neuroforaminal pathology with radicular symptoms. CONTRAINDICATIONS: Neck pain alone, cervical myelopathy or pathologies with central nervous system symptoms, instabilities requiring correction/instabilities. SURGICAL TECHNIQUE: Introduction of a surgical tube to the facet joint at the level to be operated on...
January 9, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29318336/-decompression-for-cervical-disc-herniation-using-the-full-endoscopic-anterior-technique-german-version
#15
REVIEW
S Oezdemir, M Komp, P Hahn, S Ruetten
OBJECTIVE: Resection of a cervical disc herniation using a full-endoscopic technique with an anterior approach. INDICATION: Fresh disc herniation with monoradicular symptoms in the upper extremity. CONTRAINDICATIONS: Pure neck pain, cervical myelopathy, older and calcified disc herniations, higher grade of instability and deformity. SURGICAL TECHNIQUE: Introduction of a guidewire and dilatator to a cervical disc using an anterior approach...
January 9, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29315979/prevention-of-pressure-ulcers-in-patients-undergoing-sub-acute-rehabilitation-after-severe-brain-injury-an-observational-study
#16
Marianne Brostrup Sachs, Mia Moth Wolffbrandt, Ingrid Poulsen
OBJECTIVE: The aim of this study was to uncover efforts made by healthcare professionals to prevent pressure ulcers (PUs) in patients with severe brain injury undergoing treatment at a sub-acute rehabilitation department. BACKGROUND: PUs is a major burden for patients and also generate considerable healthcare costs. PUs are, nevertheless, prevalent in both secondary and primary care. DESIGN: In this qualitative study, we performed 24-hour observation on four patients undergoing rehabilitation for severe brain injury...
January 9, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29313906/respiratory-complications-of-anaesthesia
#17
REVIEW
G H Mills
Postoperative pulmonary complications are a major determinant of outcome for patients and consume huge resources within hospital, particularly in critical care. Prediction and anticipation of postoperative pulmonary complications are vital for patient selection and, in some cases, for informed patient consent. Being able to assess the likelihood of postoperative pulmonary complications also allows research into methods to reduce them by allowing allocation of patients to the appropriate arms of research trials...
January 2018: Anaesthesia
https://www.readbyqxmd.com/read/29313885/interferon-%C3%AE-treatment-increases-endocannabinoid-and-related-n-acylethanolamine-levels-in-t84-human-colon-carcinoma-cells
#18
Mireille Alhouayek, Linda Rankin, Sandra Gouveia-Figueira, Christopher J Fowler
BACKGROUND AND PURPOSE: Endocannabinoids and related N-acylethanolamines (NAEs) are involved in regulation of gut function, but relatively little is known as to whether inflammatory cytokines such as interferon γ (IFNγ) affect their levels. We have investigated this in vitro using T84 colon cancer cells, which when cultured in monolayers differentiate to form adult colonic crypt-like cells with excellent permeability barrier properties. EXPERIMENTAL APPROACH: NAE levels were determined by ultra-performance liquid chromatography-tandem mass spectrometric analysis...
January 3, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29309180/poliomyelitis-and-its-management-in-the-hospital-of-stara-gora-slovenia-in-memoriam-dr-hilda-veli%C3%A4-kov
#19
REVIEW
Michele Schincariol
In the years between 1956 - 1958 Slovenia faced a poliomyelitis epidemic in which around 400 people were affected, one tenth of them died, and a big part of the population was left with consequences of this disease and its long-lasting rehabilitation. From 1952 to 1962 the facility of Stara Gora offered shelter and physical rehabilitation with up-to-date treatments such as oscillation and minimal joint mobilisation, hydrotherapy, irradiation, and electrical stimulation to 1124 children. During this period 200 children suffering from poliomyelitis were admitted to a specialized ward...
December 2017: Acta Medico-historica Adriatica: AMHA
https://www.readbyqxmd.com/read/29307576/oxidative-stress-biomarkers-in-type-2-diabetes-mellitus-for-assessment-of-cardiovascular-disease-risk
#20
REVIEW
Roy Robson, Avinash R Kundur, Indu Singh
AIMS: Type-2 Diabetes Mellitus (T2DM) is one of the most prevalent and progressive metabolic conditions affecting approximately 8.5% of the global population. Individuals with T2DM have a significantly increased risk of developing chronic conditions such as cardiovascular disease (CVD) and its associated complications, therefore, it is of great importance to establish strategies for combatting T2DM and its associated chronic conditions. Current literature has identified several biomarkers that are known to play a key role in the pathogenesis of CVD...
December 30, 2017: Diabetes & Metabolic Syndrome
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