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https://www.readbyqxmd.com/read/28205484/a-biomechanical-comparison-of-different-knots-tied-on-fibrewire-suture
#1
Jackson Jiang, Ita Suzana Mat Jais, Andrew Kean Tuck Yam, Duncan Angus McGrouther, Shian Chao Tay
BACKGROUND: Synthetic sutures such as Fiberwire used in flexor tendon repairs have high tensile strength. Proper application allows early mobilisation, decreasing morbidity from repair rupture and adhesions while preserving range of motion. Suture stiffness can cause poorer knot holding, contributing to gapping, peritendinous adhesions or rupture. Previous studies recommended more throws in knots tied on Fiberwire to prevent knot slippage. These larger knots are voluminous and prominent...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28202426/integrated-platform-for-home-services-using-new-products-and-services-for-senior-citizens-call-cnav-carsat-2015
#2
Michel Noguès, Daniel Laune, Delphine Paccard, Anne-Laure Coupet, Justine Millot-Keurinck, Narjis Bototo, Marine Bertrand, Jean Bousquet
This project is part of: i) the risks of ageing prevention policy of the French retirement and occupational health insurance agency of Languedoc Roussillon (Carsat-LR) and ii) the European innovation partnership on active and healthy ageing (EIP on AHA). It aims to support senior citizens who live independently and have been identified at risk of frailty on a social or health level. The purpose is to increase legibility as well as technical and financial access to innovations for vulnerable seniors who are remote from the digital era, through a multiservice user-friendly platform...
February 15, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28196553/association-between-body-energy-content-in-the-dry-period-and-post-calving-production-disease-status-in-dairy-cattle
#3
G L Smith, N C Friggens, C J Ashworth, M G G Chagunda
The transition from gestation to lactation is marked by significant physiological changes for the individual cow such that disease incidence is highest in early lactation. Around the time of calving, cows rely on mobilisation of body energy reserves to fill the energy deficit created by an increase in nutrient demands at a time of restricted feed intake. It is well established that monitoring of body energy reserves in lactation is an important component of herd health management. However, despite their influence on future health and productivity, monitoring of body energy reserves in the dry period is often sparse...
February 15, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28190550/overcoming-nursing-barriers-to-intensive-care-unit-early-mobilisation-a-quality-improvement-project
#4
Oluwatobi O Hunter, Elisabeth L George, Dianxu Ren, Douglas Morgan, Margaret Rosenzweig, Patricia Klinefelter Tuite
OBJECTIVES: To increase adherence with intensive care unit mobility by developing and implementing a mobility training program that addresses nursing barriers to early mobilisation. DESIGN: An intensive care unit mobility training program was developed, implemented and evaluated with a pre-test, immediate post-test and eight-week post-test. Patient mobility was tracked before and after training. SETTING: A ten bed cardiac intensive care unit...
February 9, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28190421/sperm-gamma-aminobutyric-acid-type-a-receptor-delta-subunit-gabrd-and-its-interaction-with-purinergic-p2x2-receptors-in-progesterone-induced-acrosome-reaction-and-male-fertility
#5
Wenming Xu, Ke Wang, Yan Chen, Xiao Tong Liang, Mei Kuen Yu, Huanxun Yue, M Louise Tierney
The mechanism underlying the non-genomic action of progesterone in sperm functions and related Ca2+ mobilisation remains elusive. Herein we report the expression of gamma-aminobutyric acid type A receptor delta subunit (GABRD) in human and rodent sperm and its involvement in mediating the progesterone-induced acrosome reaction. GABRD was localised in the sperm head/neck region. A δ(392-422)-specific inhibitory peptide against GABRD blocked the progesterone-induced acrosome reaction and the associated increase in intracellular Ca2+...
February 13, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28173736/the-alternative-receptor-for-complement-component-5a-c5ar2-conveys-neuroprotection-in-traumatic-spinal-cord-injury
#6
Patrick Biggins, Faith Brennan, Stephen Taylor, Trent Woodruff, Marc Ruitenberg
This study investigated the role of the secondary receptor for complement activation fragment C5a, C5aR2, in secondary inflammatory pathology following contusive spinal cord injury (SCI) in mice. <i>C5ar2<sup>-/-</sup></i> mice exhibited decreased intraparenchymal TNFα and IL-6 acutely after injury but these reductions did not translate into improved outcomes. We show that loss of C5aR2 leads to increased lesion volumes, reduced myelin sparing and significantly worsened recovery from SCI in <i>C5ar2<sup>-/-</sup></i> animals compared to wild-type (WT) controls...
February 7, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28171819/mobilisation-of-microbial-indicators-microbial-source-tracking-markers-and-pathogens-after-rainfall-events
#7
Cristina García-Aljaro, Julia Martín-Díaz, Enric Viñas-Balada, William Calero-Cáceres, Francisco Lucena, Anicet R Blanch
Climate change is expected to affect the Mediterranean region by causing an increase in the number of heavy rainfall events. The aim of this study was to assess the effect of extreme river flow variations due to rainfall on the persistence and mobilisation of various microorganisms. These included faecal pollution indicators (Escherichia coli (EC), somatic coliphages (SOMCPH) and sulphite reducing clostridia spores (SRC)), microbial source tracking indicators (Bacteroides thetaiotaomicron GA17 strain phages (GA17PH) and sorbitol fermenting bifidobacteria (SFBIF)), and two pathogens (Salmonella spp and Enterovirus)...
February 2, 2017: Water Research
https://www.readbyqxmd.com/read/28166980/effect-of-energy-balance-profiles-on-metabolic-and-reproductive-response-in-holstein-and-swedish-red-cows
#8
T Ntallaris, P Humblot, R Båge, Y Sjunnesson, J Dupont, B Berglund
This study examined the effect of two feeding levels during the antepartum and postpartum period on reproductive performance and blood metabolites (glucose, non-esterified fatty acids (NEFA), insulin) in primiparous Holstein and Swedish Red (SRB) cows, in order to identify possible differences in the way these breeds respond to negative energy balance after calving. A total of 44 cows (22 Holstein, 22 SRB) kept in a loose housing system were included in the study. The control group (HE, n = 23) was fed a diet for high-producing cows (target 35 kg/d energycorrected milk, ECM)...
March 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28166798/identifying-and-characterising-health-policy-and-system-relevant-documents-in-uganda-a-scoping-review-to-develop-a-framework-for-the-development-of-a-one-stop-shop
#9
Boniface Mutatina, Robert Basaza, Ekwaro Obuku, John N Lavis, Nelson Sewankambo
BACKGROUND: Health policymakers in low- and middle-income countries continue to face difficulties in accessing and using research evidence for decision-making. This study aimed to identify and provide a refined categorisation of the policy documents necessary for building the content of a one-stop shop for documents relevant to health policy and systems in Uganda. The on-line resource is to facilitate timely access to well-packaged evidence for decision-making. METHODS: We conducted a scoping review of Uganda-specific, health policy, and systems-relevant documents produced between 2000 and 2014...
February 6, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28165840/adapting-and-implementing-open-dialogue-in-the-scandinavian-countries-a-scoping-review
#10
Niels Buus, Aida Bikic, Elise Kragh Jacobsen, Klaus Müller-Nielsen, Jørgen Aagaard, Camilla Blach Rossen
Open Dialogue is a resource-oriented mental health approach, which mobilises a crisis-struck person's psychosocial network resources. This scoping review 1) identifies the range and nature of literature on the adoption of Open Dialogue in Scandinavia in places other than the original sites in Finland, and 2) summarises this literature. We included 33 publications. Most studies in this scoping review were published as "grey" literature and most grappled with how to implement Open Dialogue faithfully. In the Scandinavian research context, Open Dialogue was mainly described as a promising and favourable approach to mental health care...
February 6, 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28162047/design-of-a-patient-information-leaflet-in-a-surgical-centre-in-cambodia
#11
Alexander Thomas Schade, Thomas Mendes da Costa, Jim Gollogly, Fergal Monsell
Hand deformities cause a large surgical burden on Cambodian society. They significantly affect the quality of life, limit hand function and can cause severe mental health issues. The visited surgical centre provides free rehabilitative surgery in Phnom Penh for those unable to afford private or public healthcare. As part of the postoperative care provided, a team of local Khmer physiotherapists help patients with early mobilisation, passive and active movements, and functional exercises. Leaflets are widespread in high-income countries, but are scarce in low-income countries...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28160606/discovery-and-pharmacological-characterization-of-succinate-receptor-sucnr1-gpr91-agonists
#12
Pierre Geubelle, Julie Gilissen, Sébastien Dilly, Laurence Poma, Nadine Dupuis, Céline Laschet, Dayana Abboud, Asuka Inoue, François Jouret, Bernard Pirotte, Julien Hanson
BACKGROUND AND PURPOSE: The succinate receptor (SUCNR1 or GPR91) has been described as a metabolic sensor that may be involved in homeostasis. Notwithstanding its implication in important (patho)physiological processes, the function of SUCNR1 has remained elusive because no pharmacological tools were available. We report on the discovery of the first family of synthetic potent agonists. EXPERIMENTAL APPROACH: We screened a library of succinate analogues and analysed their activity on SUCNR1...
February 4, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28158954/abortion-in-tunisia-after-the-revolution-bringing-a-new-morality-into-the-old-reproductive-order
#13
Irene Maffi
The emergence of Islamist movements and religious symbolic repertoires in the aftermath of the Tunisian revolution has elicited the political, moral, and practical contestation of women's right to abortion. While, after several heated debates, the law was eventually not modified, several practitioners working in government family planning clinics have changed their behaviour preventing women getting abortions. Pre-existing state and medical logics, political uncertainties, and new religious and moralising discourses have determined abortion practices in the government health-care facilities generating unequal treatments according to women's marital status, class, and education...
February 3, 2017: Global Public Health
https://www.readbyqxmd.com/read/28155873/alteration-of-multiple-leukocyte-gene-expression-networks-is-linked-with-magnetic-resonance-markers-of-prognosis-after-acute-st-elevation-myocardial-infarction
#14
A Teren, H Kirsten, F Beutner, M Scholz, L M Holdt, D Teupser, M Gutberlet, J Thiery, G Schuler, I Eitel
Prognostic relevant pathways of leukocyte involvement in human myocardial ischemic-reperfusion injury are largely unknown. We enrolled 136 patients with ST-elevation myocardial infarction (STEMI) after primary angioplasty within 12 h after onset of symptoms. Following reperfusion, whole blood was collected within a median time interval of 20 h (interquartile range: 15-25 h) for genome-wide gene expression analysis. Subsequent CMR scans were performed using a standard protocol to determine infarct size (IS), area at risk (AAR), myocardial salvage index (MSI) and the extent of late microvascular obstruction (lateMO)...
February 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28148439/-spa-therapies-therapeutic-education-and-osteoarthritis
#15
Christian-François Roques, Claude-Eugène Bouvier
For people with osteoarthritis, spa therapies can provide care, education and prevention resources. The therapeutic education programme Educ'arthrose, currently being examined by a French Regional Health Agency, mobilises nurses.
August 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/28148435/-towards-real-recognition-of-osteoarthritis
#16
Laurent Grange
Osteoarthritis suffers from a low profile among society and public authorities. However, the impact of this disease on the daily lives of those affected is considerable. Work remains to be done to ensure greater recognition of the disease and improve patient management. The osteoarthritis forum, which ran from September 2014 to June 2015, put forward proposals brought together in a white paper on osteoarthritis. Mobilisation is underway.
August 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/28136021/prevention-diagnosis-and-treatment-of-venous-thromboembolism
#17
Richard Greenall
Venous thromboembolism (VTE) occurs more frequently in older people. For those nursing older people in a variety of settings, knowledge of VTE prevention, diagnosis and treatment is essential. This article discusses simple, practical measures that can be used to reduce the risk of VTE, including good hydration and promotion of mobilisation. It also discusses how a VTE forms, the signs and symptoms, and the methods used to diagnose and treat VTE. In recent years new drugs have been licensed to treat patients with VTE called direct oral anticoagulants...
January 31, 2017: Nursing Older People
https://www.readbyqxmd.com/read/28135864/-naloxone-works-the-politics-of-knowledge-in-evidence-based-drug-policy
#18
Kari Lancaster, Carla Treloar, Alison Ritter
For over 20 years, drug policy experts have been calling for the wider availability of naloxone, to enable lay overdose witnesses to respond to opioid overdose events. However, the 'evidence base' for peer-administered naloxone has become a key point of contention. This contention opens up critical questions about how knowledge ('evidence') is constituted and validated in drug policy processes, which voices may be heard, and how knowledge producers secure privileged positions of influence. Taking the debate surrounding peer-administered naloxone as a case study, and drawing on qualitative interviews with individuals (n = 19) involved in the development of naloxone policy in Australia, we examine how particular kinds of knowledge are rendered 'useful' in drug policy debates...
January 1, 2017: Health (London)
https://www.readbyqxmd.com/read/28132601/stigma-violence-and-hiv-vulnerability-among-transgender-persons-in-sex-work-in-maharashtra-india
#19
Deepika Ganju, Niranjan Saggurti
Among marginalised groups in India, HIV prevalence is highest among transgender persons; however, little is known about their HIV vulnerability. This study describes transgender sex workers' experiences of stigma and violence, a key driver of the HIV epidemic, and explores their coping responses. In-depth interviews were conducted with 68 respondents in Maharashtra state, India. Findings show that respondents face pervasive stigma and violence due to multiple marginalised social identities (transgender status, sex work, gender non-conformity), which reinforce and intersect with social inequities (economic and housing insecurity, employment discrimination, poverty), fuelling HIV vulnerability at the micro, meso and macro levels...
January 30, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28129378/intensity-of-african-humid-periods-estimated-from-saharan-dust-fluxes
#20
Werner Ehrmann, Gerhard Schmiedl, Sarah Beuscher, Stefan Krüger
North Africa experienced dramatic changes in hydrology and vegetation during the late Quaternary driven by insolation-induced shifts of the tropical rain belt and further modulated by millennial-scale droughts and vegetation-climate feedbacks. While most past proxy and modelling studies concentrated on the temporal and spatial dynamics of the last African humid period, little is known about the intensities and characteristics of pre-Holocene humid periods. Here we present a high-resolution record of fine-grained eastern Saharan dust from the Eastern Mediterranean Sea spanning the last 180 kyr, which is based on the clay mineral composition of the marine sediments, especially the kaolinite/chlorite ratio...
2017: PloS One
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