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Vertebroplasty

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https://www.readbyqxmd.com/read/28619686/low-dose-bmp-2-is-sufficient-to-enhance-the-bone-formation-induced-by-an-injectable-plga-fiber-reinforced-brushite-forming-cement-in-a-sheep-defect-model-of-lumbar-osteopenia
#1
Francesca Gunnella, Elke Kunisch, Matthias Bungartz, Stefan Maenz, Victoria Horbert, Long Xin, Joerg Mika, Juliane Borowski, Sabine Bischoff, Harald Schubert, Peter Hortschansky, Andre Sachse, Bernhard Illerhaus, Jens Günster, Jörg Bossert, Klaus D Jandt, Frank Plöger, Raimund W Kinne, Olaf Brinkmann
BACKGROUND CONTEXT: Bioresorbable calcium phosphate cement (CPC) may be suitable for vertebroplasty/kyphoplasty of osteoporotic vertebral fractures. However, additional targeted delivery of osteoinductive bone morphogenetic proteins (BMPs) in the CPC may be required to counteract the augmented local bone catabolism and support complete bone regeneration. PURPOSE: The study aimed at testing an injectable, poly (l-lactide-co-glycolide) acid (PLGA)-fiber reinforced, brushite-forming cement (CPC) containing low-dose bone morphogenetic protein BMP-2 in a sheep lumbar osteopenia model...
June 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28619021/treatment-of-thoracolumbar-burst-fractures-by-short-segment-pedicle-screw-fixation-using-a-combination-of-two-additional-pedicle-screws-and-vertebroplasty-at-the-level-of-the-fracture-a-finite-element-analysis
#2
Jen-Chung Liao, Weng-Pin Chen, Hao Wang
BACKGROUND: Traditional one-above and one-below four-screw posterior short-segment instrumentation is used for unstable thoracolumbar burst fractures. However, this method has a high rate of implant failure and early loss of reduction. The purpose of this study was to use finite element (FE) analysis to determine the effect of treating thoracolumbar burst fractures by short-segment pedicle screw fixation using a combination of two additional pedicle screws and vertebroplasty at the level of the fracture...
June 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28607815/vertebroplasty-for-vertebral-compression-fractures-placebo-or-effective
#3
EDITORIAL
Arvin R Wali, Joel R Martin, Robert Rennert, Daniel K Resnick, William Taylor, Peter Warnke, Clark C Chen
Vertebral compression fractures (VCFs) are a major cause of pain and disability. Here, we reviewed six randomized control trials (RCTs) focusing on the efficacy vs. placebo effect of vertebroplasty (VP) for symptomatic VCF. Four RCTs involved a nonsurgically treated control group. Two RCTs compared the use of VP vs. a sham surgery control group. Notably, RCTs comparing nonsurgically treated patients as a control group vs. those undergoing VP uniformly reported that VP contributed to improved pain relief. In contrast, RCTs comparing sham surgery vs...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28602487/using-side-opening-injection-cannulas-to-prevent-cement-leakage%C3%A2-in%C3%A2-percutaneous-vertebroplasty-for-osteoporotic-vertebral%C3%A2-compression-fractures-does-it-really-work
#4
Jigang Li, Tao Li, Qiuhong Ma, Jianmin Li
BACKGROUND: Percutaneous vertebroplasty has been widely applied in the treatment of osteoporotic vertebral compression fractures over the past two decades. However as one of the major complications, the rate of cement leakage seems not to be decreased significantly. In this study, the rate of cement leakage was compared between two groups using two different cement injection cannulas. The purpose was to determine the efficacy of side-opening cannula on preventing cement leakage in vertebroplasty for the treatment of osteoporotic vertebral compression fractures...
June 8, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28580716/preparation-and-characterization-of-injectable-pmma-strontium-substituted-bioactive-glass-bone-cement-composites
#5
I Goñi, R Rodríguez, I García-Arnáez, J Parra, M Gurruchaga
In most minimally-invasive procedures used to address severe pain arising from compression fractures of the vertebral bodies, such as percutaneous vertebroplasty (PVP), a poly(methyl methacrylate) (PMMA) bone cement is used. Shortcomings of this type of cement, such as high exotherm temperature and lack of bioactivity, are well known. We prepared different formulations of a composite bone cement, whose solid constituents consisted of PMMA beads and particles of a bioactive glass (BG), where 0-20%(w/w) of the calcium component was substituted by strontium...
June 5, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28578082/an-updated-comparison-of-high-and-low-viscosity-cement-vertebroplasty-in-the-treatment-of-osteoporotic-thoracolumbar-vertebral-compression-fractures-a-retrospective-cohort-study
#6
Zhao-Fei Zhang, Jun-Long Yang, Huan-Chang Jiang, Zhen Lai, Feng Wu, Yong-Quan Pan, Zhi-Xiang Liu
OBJECTIVE: This study mainly aimed to evaluate complications of cement leakage for osteoporotic thoracolumbar vertebral compression fractures by PVP using HVC, and access the clinical efficacy. METHODS: Between May 2013 and June 2015, 66 patients with osteoporotic thoracolumbar vertebral compression fractures, who underwent PVP (36 HVC and 30 LVC) in our hospital, were enrolled. Cement leakage, Visual Analog Scale (VAS), Oswestry Disability Index (ODI), refracture of the cemented vertebrae, and adjacent vertebral fractures were evaluated...
May 31, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28573824/bone-cement-cardiac-and-pulmonary-embolism
#7
Tomás F Cianciulli, Diego E Mc Loughlin, Luis A Morita, María C Saccheri, Jorge A Lax
This case describes a complication of bone cement use. A 65-year-old male patient with back spine trauma caused by a fall, underwent a percutaneous vertebroplasty. Five years later, he consulted for palpitations, and the electrocardiogram showed supraventricular arrhythmia. A transthoracic two-dimensional echocardiography showed a hyperechogenic linear structure of 7 cm length, running from the lateral wall of the right ventricle to the right atrium through the tricuspid valve. This foreign body, which was suspicious for bone cement embolism, appeared rigid and was attached at the lateral wall of the right ventricle, with its proximal end free in the right atrium...
June 1, 2017: Echocardiography
https://www.readbyqxmd.com/read/28571789/virtual-reality-based-simulators-for-spine-surgery-a-systematic-review
#8
REVIEW
Michael Pfandler, Marc Lazarovici, Philipp Stefan, Patrick Wucherer, Matthias Weigl
BACKGROUND CONTEXT: Virtual reality (VR) based simulators offer numerous benefits and are very useful in assessing and training surgical skills. Although they are standard in some surgical subspecialties, their actual use in spinal surgery remains unclear. Currently, only technical reviews of VR based simulators are available for spinal surgery. PURPOSE: Thus, we performed a systematic review which examined the existing research on VR based simulators in spinal procedures...
May 29, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28566777/surgical-treatment-of-secondary-fractures-after-percutaneous-vertebroplasty-a-retrospective-study
#9
Jiang-Jun Zhu, Dong-Sheng Zhang, Su-Liang Lou, Yong-Hong Yang
BACKGROUND: Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are effective procedures for the treatment of vertebral compression fractures (VCFs). However, recent studies have reported that secondary VCFs develop in patients after PVP or PKP treatment. This study aimed to investigate the clinical characteristics and management of secondary fractures after PVP or PKP. MATERIALS AND METHODS: 599 cases who had vertebral compression fracture and underwent PVP or PKP between September 2008 and June 2014 were enrolled, including 121 males and 478 females...
May 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28552698/a-novel-approach-for-percutaneous-vertebroplasty-based-on-preoperative-ct-based-3-dimensional-model-design-technical-note
#10
Jian Li, JiSheng Lin, JunChuan Xu, Hai Meng, Nan Su, ZiHan Fan, JinJun Li, Yong Yang, Dong Li, BingQiang Wang, Qi Fei
OBJECTIVE: To describe a new technique for the efficient use of preoperative planning based on preoperative CT-based 3-Dimensional model design for percutaneous vertebroplasty (PVP) in a patient with osteoporotic vertebral compression fracture (OVCF). METHODS: A 76-year-old woman with acute OVCF (L1 level) accepted a novel precise PVP. A 3D model of thoracolumbar vertebrae (T12-L2) based on preoperative CT scanning data and a simulative PVP (via bilateral transpedicular approach) were built in Materiaise's interactive medical image control system (MIMICS) software...
May 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28542552/osteoporosis-associated-vertebral-fractures-health-economic-implications
#11
Julian Joestl, Nikolaus Lang, Adam Bukaty, Thomas M Tiefenboeck, Patrick Platzer
INTRODUCTION: Osteoporosis-associated vertebral fractures represent an increasing clinical and public health problem, one with important socioeconomic effects within western countries. The purpose of this study was to analyse demographic, medical, gender and socioeconomic aspects of osteoporotic vertebral fractures of the thoracic or lumbar spine over a period of at least 10-years. MATERIAL AND METHODS: Included for analysis were 694 patients who had suffered a vertebral fracture due to primary or secondary osteoporosis, and who were treated at our Level-I trauma center between 2000 and 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28535560/nomogram-for-predicting-intradiscal-cement-leakage-following-percutaneous-vertebroplasty-in-patients-with-osteoporotic-related-vertebral-compression-fractures
#12
Bin-Yan Zhong, Shi-Cheng He, Hai-Dong Zhu, Tao Pan, Wen Fang, Li Chen, Jin-He Guo, Gang Deng, Guang-Yu Zhu, Gao-Jun Teng
BACKGROUND: Intradiscal cement leakage (ICL) is a common complication following percutaneous vertebroplasty (PVP). However, the risk factors for such a complication are under debate and there is no accurate predictive nomogram to predict ICL. OBJECTIVES: To establish an effective and novel nomogram for ICL following PVP in patients with osteoporotic-related vertebral compression fractures (OVCFs). STUDY DESIGN: This was a retrospective study approved by the Institutional Review Board of our institution...
May 2017: Pain Physician
https://www.readbyqxmd.com/read/28526207/3d-echocardiographic-diagnosis-of-right-ventricular-perforation-with-polymethylmethacrylate-particles-after-vertebroplasty
#13
Stefaan Bouchez, Eckhard Mauermann, Tine Philipsen, Patrick Wouters
No abstract text is available yet for this article.
February 16, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28522402/prophylactic-vertebral-cement-augmentation-at-the-uppermost-instrumented-vertebra-and-rostral-adjacent-vertebra-for-the-prevention-of-proximal-junctional-kyphosis-and-failure-following-long-segment-fusion-for-adult-spinal-deformity
#14
George M Ghobrial, Daniel G Eichberg, John Paul G Kolcun, Karthik Madhavan, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
BACKGROUND CONTEXT: Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are common problems after long segment (>5 levels) thoracolumbar instrumented fusions in the treatment of adult spinal deformity (ASD). No specific surgical strategy has definitively been shown to lower the risk of PJK as the result of a multifactorial etiology. PURPOSE: To assess the incidence of PJK and PJF in patients treated with prophylactic polymethylmethacrylate(PMMA) cement augmentation at the uppermost instrumented vertebrae(UIV) and rostral adjacent vertebrae(UIV+1)...
May 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28513888/pain-quality-of-life-and-safety-outcomes-of-kyphoplasty-for-vertebral-compression-fractures-report-of-a-task-force-of-the-american-society-for-bone-and-mineral-research
#15
A J Rodriguez, H A Fink, L Mirigian, N Guañabens, R Eastell, K Akesson, D C Bauer, P R Ebeling
The relative efficacy and harms of balloon kyphoplasty (BK) for treating vertebral compression fractures (VCF) are uncertain. We searched multiple electronic databases to March 2016 for randomised and quasi-randomised controlled trials comparing BK with control treatment (non-surgical management [NSM], percutaneous vertebroplasty [PV], KIVA®, vertebral body stenting, or other) in adults with VCF. Outcomes included back pain, back disability, quality of life (QoL), new VCF and adverse events (AE). One reviewer extracted data, a second checked accuracy, and two rated risk of bias (ROB)...
May 17, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28512047/preoperative-planning-of-lateral-entry-point-is-necessary-in-percutaneous-lumbar-5th-vertebroplasty
#16
Hsi-Hsien Lin, Ming-Chau Chang, Po-Hsin Chou, Pei-I Hung, Shih-Tien Wang, Chien-Lin Liu
BACKGROUND: To compare treatment outcomes and complications between the computer-assisted preoperative planning of lateral entry approach and the traditional approach for L5 percutaneous vertebroplasty. METHODS: This prospective randomized clinical study was performed from January 2008 to December 2014, wherein 68 patients who received L5 percutaneous vertebroplasty were randomly divided into either group A, for which the traditional trans-pedicle approach was used, or group B, for which the computer-assisted lateral entry point approach was used for L5 percutaneous vertebroplasty...
May 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28506822/the-effect-of-prophylactic-vertebroplasty-on-the-incidence-of-proximal-junctional-kyphosis-and-proximal-junctional-failure-following-posterior-spinal-fusion-in-adult-spinal-deformity-a-5-year-follow-up-study
#17
Tina Raman, Emily Miller, Christopher T Martin, Khaled Kebaish
BACKGROUND CONTEXT: The incidence of proximal junctional kyphosis (PJK) ranges from 5-46% following adult spinal deformity (ASD) surgery. Approximately 66-76% of PJK occurs within 3 months of surgery. A subset of these patients, reportedly 26-47%, develop proximal junctional failure (PJF) within 6 months postoperatively. To date, there are no studies evaluating the impact of prophylactic vertebroplasty on PJK/PJF incidence at long term follow-up. PURPOSE: The purpose of this study is to evaluate the long term radiographic and clinical outcomes, and incidence of PJK and PJF, after prophylactic vertebroplasty for long segment thoracolumbar posterior spinal fusion...
May 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28505594/the-rheological-behavior-of-a-fast-setting-calcium-phosphate-bone-cement-and-its-dependence-on-deformation-conditions
#18
Erdem Şahin, Dilhan M Kalyon
Calcium phosphate cements are osteoconductive biomaterials that are widely used for bone repair and regeneration applications, including spinal fusion, vertebroplasty, khyphoplasty, cranioplasty and periodontal surgeries. The flow and deformation behavior (rheology) and injectability of the calcium phosphate bone cements to the treatment site are governed by the setting kinetics of the cement during which the initially flowable, viscous cement paste transforms into a rigid elastic solid. Here time-dependent development of the linear viscoelastic properties of a brushite-forming calcium phosphate cement are characterized and linked to the mechanism and kinetics of the setting reaction and to the injectability window available during the surgical applications of the cement...
May 10, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28499893/vertebroplasty-and-interventional-radiology-procedures-for-bone-metastases
#19
Jean-Denis Laredo, Jacques Chiras, Salim Kemel, Lokmane Taihi, Bassam Hamze
Advances in cancer treatments have lengthened the survival of patients with bone metastases. Optimal control of the symptoms and prevention of the complications associated with bone metastases improve quality of life. Achieving these goals increasingly involves interventional radiology procedures. These include bone consolidation and analgesic techniques such as cementoplasty (vertebroplasty at the spine); percutaneous implantation of screws, metallic reinforcement devices, or intraosseous implants; and tumor destruction using thermal methods (radiofrequency and cryotherapy), chemicals (alcohol), and drugs (chemoembolization), which have fewer indications...
May 9, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28490865/poor-1st-year-adherence-to-anti-osteoporotic-therapy-increases-the-risk-of-mortality-in-patients-with-magnetic-resonance-imaging-proven-acute-osteoporotic-vertebral-fractures
#20
Ying-Chou Chen, Wei-Che Lin
AIM: Anti-osteoporotic therapy requires years of proper compliance to reduce the risk of fractures. This study investigated the effects of 1st-year adherence to anti-osteoporotic treatment on the risk of mortality in patients with magnetic resonance imaging-proven acute osteoporotic vertebral fractures after vertebroplasty. PATIENTS AND METHODS: This retrospective study included 294 patients (252 females; mean age, 73.93±7.18 years) with osteoporosis and acute vertebral fractures treated with vertebroplasty between January 2001 and December 2007...
2017: Patient Preference and Adherence
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