Sudhir Jadhao, Candice Davison, Eileen Roulis, Simon Lee, Tamika Campbell, Reece Griffin, Maree Toombs, Alex Brown, Maree Perry, Bushra Nasir, David O Irving, Catherine A Hyland, Robert L Flower, Shivashankar H Nagaraj
BACKGROUND: Hematological disorders are often treated with blood transfusions. Many blood group antigens and variants are population-specific, and for patients with rare blood types, extensive donor screening is required to find suitable matches for transfusion. There is a scarcity of knowledge regarding blood group variants in Aboriginal Australian populations, despite a higher need for transfusion due to the higher prevalence of renal diseases and anaemia. MATERIALS AND METHODS: In this study, we applied next-generation sequencing and analysis to 245 samples obtained from Aboriginal Australians from South-East Queensland, to predict antigen phenotypes for 36 blood group systems...
March 11, 2024: Blood Transfusion