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https://www.readbyqxmd.com/read/29791706/use-of-a-noblestitch%C3%A2-el-device-for-pfo-closure
#1
Emanuela de Cillis, Tommaso Acquaviva, Pasquale D'Alessandro, Alessandro Santo Bortone
Cryptogenic stroke is the final diagnosis in almost 40% of ischemic acute cerebrovascular events. There is currently no definitive clinical evidence that percutaneous closure of patent foramen ovale (PFO) can prevent the recurrence of stroke or transient ischemic attack (TIA). Identification of the causes of neurologic ischemic syndromes is essential for any strategy intended to prevent the catastrophic consequences of cerebral infarction. Since the initial reports of an unexpectedly high prevalence of PFO in younger patients with cryptogenic stroke in 1988, there has been growing interest and experience in diagnosing and treating these patients, both medically and/or with percutaneous closure, in particular for the potential to eliminate paradoxical embolism via PFO, which is a likely mechanism for stroke in these patients...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29790185/a-combined-epicardial-implantation-and-subsequent-extraction-strategy-in-pacemaker-device-infection-in-pacemaker-dependent-patients
#2
Floris S van den Brink, Vincent F van Dijk, Lucas Va Boersma, Maurtis Cef Wijffels, John Gelissen, Edgar Daeter, Uday Sonker, Jippe Balt
INTRODUCTION: Treatment of pacemaker (PM) device infections is challenging in pacemaker dependent patients. We propose a novel implantation strategy for this group of patients. METHODS: Patients who were PM dependent and were admitted with a PM infection received a combined procedure of LV epicardial implantation of a PM lead and subsequent extraction of the infected system. No temporary pacing wire was used and the PM generator was placed in the left flank. RESULTS: Between 2012 and 2015 we treated 16 patients who were PM dependent with a PM infection...
May 23, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29785878/five-year-outcomes-with-pci-guided-by-fractional-flow-reserve
#3
Panagiotis Xaplanteris, Stephane Fournier, Nico H J Pijls, William F Fearon, Emanuele Barbato, Pim A L Tonino, Thomas Engstrøm, Stefan Kääb, Jan-Henk Dambrink, Gilles Rioufol, Gabor G Toth, Zsolt Piroth, Nils Witt, Ole Fröbert, Petr Kala, Axel Linke, Nicola Jagic, Martin Mates, Kreton Mavromatis, Habib Samady, Anand Irimpen, Keith Oldroyd, Gianluca Campo, Martina Rothenbühler, Peter Jüni, Bernard De Bruyne
Background We hypothesized that fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) would be superior to medical therapy as initial treatment in patients with stable coronary artery disease. Methods Among 1220 patients with angiographically significant stenoses, those in whom at least one stenosis was hemodynamically significant (FFR, ≤0.80) were randomly assigned to FFR-guided PCI plus medical therapy or to medical therapy alone. Patients in whom all stenoses had an FFR of more than 0...
May 22, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29783574/re-the-cumulative-burden-of-surviving-childhood-cancer-an-initial-report-from-the-st-jude-lifetime-cohort-study-sjlife
#4
Matthew J Resnick
No abstract text is available yet for this article.
June 2018: Journal of Urology
https://www.readbyqxmd.com/read/29779524/inappropriate-automatic-mode-switching-episodes-what-s-the-mechanism
#5
Juan Benezet-Mazuecos, José Antonio Iglesias, Juan José de la Vieja, Angel Miracle, Pepa Sanchez-Borque, José Manuel Rubio
We present a case series of five patients reporting abnormal automatic mode switching (AMS) episodes during routinary cardiac defibrillator (ICD) and pacemaker (PM) follow-up. This non-previously described phenomenon was reported to St. Jude Medical (Abbott) Technical Support that confirmed the inappropriate automatic mode switching.
May 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29778738/risk-adapted-therapy-for-young-children-with-medulloblastoma-sjyc07-therapeutic-and-molecular-outcomes-from-a-multicentre-phase-2-trial
#6
Giles W Robinson, Vasilisa A Rudneva, Ivo Buchhalter, Catherine A Billups, Sebastian M Waszak, Kyle S Smith, Daniel C Bowers, Anne Bendel, Paul G Fisher, Sonia Partap, John R Crawford, Tim Hassall, Daniel J Indelicato, Frederick Boop, Paul Klimo, Noah D Sabin, Zoltan Patay, Thomas E Merchant, Clinton F Stewart, Brent A Orr, Jan O Korbel, David T W Jones, Tanvi Sharma, Peter Lichter, Marcel Kool, Andrey Korshunov, Stefan M Pfister, Richard J Gilbertson, Robert P Sanders, Arzu Onar-Thomas, David W Ellison, Amar Gajjar, Paul A Northcott
BACKGROUND: Young children with medulloblastoma have a poor overall survival compared with older children, due to use of radiation-sparing therapy in young children. Radiotherapy is omitted or reduced in these young patients to spare them from debilitating long-term side-effects. We aimed to estimate event-free survival and define the molecular characteristics associated with progression-free survival in young patients with medulloblastoma using a risk-stratified treatment strategy designed to defer, reduce, or delay radiation exposure...
May 16, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29764833/early-prosthetic-valve-endocarditis-after-transcatheter-aortic-valve-implantation-using-st-jude-medical-portico-valve
#7
Abdalla Ibrahim, Aneeq Ahmed, Thomas Kiernan, Samer Arnous
An 87-year-old woman presented to the emergency department with a 2-week history of progressively worsening shortness of breath, fever and generalised myalgia. She underwent a transcatheter Portico aortic valve implantation for severe symptomatic aortic stenosis 3 months prior to this presentation. Examination revealed a temperature of 40°C and a systolic murmur in the aortic area. Inflammatory markers were elevated, and blood cultures were positive for methicillin-sensitive Staphylococcus aureus A possible diagnosis of infective endocarditis was made as one major and one minor criterion in the modified Duke criteria were fulfilled...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29760286/comparison-of-the-femoseal-vascular-closure-device-with-manual-compression-after-femoral-artery-puncture-post-hoc-analysis-of-a-large-scale-randomized-clinical-trial
#8
Nader Mankerious, Katharina Mayer, Senta M Gewalt, Sandra M Helde, Tareq Ibrahim, Lorenz Bott-Flügel, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Stefanie Schüpke
OBJECTIVES: To assess the safety and efficacy of arteriotomy closure with the intravascular FemoSeal vascular closure device (VCD; St. Jude Medical) compared to manual compression in patients undergoing diagnostic cardiac catheterization via the common femoral artery. BACKGROUND: There is limited evidence on the performance of individual contemporary VCDs compared to manual compression. METHODS: This is a subanalysis of 3018 patients who underwent transfemoral diagnostic coronary angiography and were randomly assigned to arteriotomy closure with either the intravascular FemoSeal VCD or manual compression within the investigator-initiated, large-scale, randomized, multicenter, open-label ISAR-CLOSURE trial...
May 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29760285/occurrence-of-incomplete-endothelialization-causing-residual-permeability-after-left-atrial-appendage-closure
#9
Mathieu Granier, Guillaume Laugaudin, François Massin, Stephane Cade, Pierre François Winum, Cornelia Freitag, Jean-Luc Pasquie
AIMS: Percutaneous left atrial appendage (LAA) occlusion is occasionally incomplete, with residual permeability of the LAA on cardiac computed tomography. The cause for this is unclear. Our objective was to determine if residual permeability was related to incomplete endothelialization. METHODS: A total of 35 consecutive patients contraindicated for anticoagulant therapy admitted for LAA occlusion were included; 12 patients received a Watchman device (Boston Scientific) and 23 patients received an Amplatzer Cardiac Plug (St...
May 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29758585/comparative-study-about-the-tensile-strength-and-yielding-mechanism-of-pacing-lead-among-major-manufacturers
#10
Chan Chi-Wo, Chan Lip-Kiong, Lam Tongny, Tsang Kin-Keung, Chan Kin-Wing
BACKGROUND: With extraction of cardiovascular implantable electronic devices (CIED) increasingly necessitated, various studies have contemplated to investigate clinical predictors for its success and complications. Intrinsic parameters of CIED leads have been studied less extensively and are the foci of this study. METHODS: Three major pacemaker manufacturers accepted invitation. Leads then underwent tensile test in-vitro with their composite tensile strength (TS) compared...
May 14, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29755074/-structural-deterioration-of-a-bovine-pericardial-valve-in-a-tricuspid-position-14-years-postoperatively-report-of-a-case
#11
Kazunori Ota, Koyu Tanaka, Naoki Asano, Shigeyoshi Gon, Masahito Saito, Kazuho Niimi, Hiromichi Inoue, Motohiko Tamura, Yuji Matsumura, Toshihiro Ohata, Hirotsugu Fukuda, Hiroshi Takano
Although nonstructural dysfunction of a bioprosthesis caused by pannus formation or native valve attachment has been well described, structural valve deterioration( SVD) caused by calcification or tear of a bioprosthesis, especially a bovine pericardial valve, is very rare in the tricuspid position. We report a case of redo tricuspid valve surgery for SVD 14 years after tricuspid valve replacement( TVR) using a Carpentier-Edwards Perimount (CEP) pericardial valve. A 71-year-old woman was referred to our hospital because of exertional dyspnea and pre-syncope...
March 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29753700/spectrum-and-prevalence-of-genetic-predisposition-in-medulloblastoma-a-retrospective-genetic-study-and-prospective-validation-in-a-clinical-trial-cohort
#12
Sebastian M Waszak, Paul A Northcott, Ivo Buchhalter, Giles W Robinson, Christian Sutter, Susanne Groebner, Kerstin B Grund, Laurence Brugières, David T W Jones, Kristian W Pajtler, A Sorana Morrissy, Marcel Kool, Dominik Sturm, Lukas Chavez, Aurelie Ernst, Sebastian Brabetz, Michael Hain, Thomas Zichner, Maia Segura-Wang, Joachim Weischenfeldt, Tobias Rausch, Balca R Mardin, Xin Zhou, Cristina Baciu, Christian Lawerenz, Jennifer A Chan, Pascale Varlet, Lea Guerrini-Rousseau, Daniel W Fults, Wiesława Grajkowska, Peter Hauser, Nada Jabado, Young-Shin Ra, Karel Zitterbart, Suyash S Shringarpure, Francisco M De La Vega, Carlos D Bustamante, Ho-Keung Ng, Arie Perry, Tobey J MacDonald, Pablo Hernáiz Driever, Anne E Bendel, Daniel C Bowers, Geoffrey McCowage, Murali M Chintagumpala, Richard Cohn, Timothy Hassall, Gudrun Fleischhack, Tone Eggen, Finn Wesenberg, Maria Feychting, Birgitta Lannering, Joachim Schüz, Christoffer Johansen, Tina V Andersen, Martin Röösli, Claudia E Kuehni, Michael Grotzer, Kristina Kjaerheim, Camelia M Monoranu, Tenley C Archer, Elizabeth Duke, Scott L Pomeroy, Redmond Shelagh, Stephan Frank, David Sumerauer, Wolfram Scheurlen, Marina V Ryzhova, Till Milde, Christian P Kratz, David Samuel, Jinghui Zhang, David A Solomon, Marco Marra, Roland Eils, Claus R Bartram, Katja von Hoff, Stefan Rutkowski, Vijay Ramaswamy, Richard J Gilbertson, Andrey Korshunov, Michael D Taylor, Peter Lichter, David Malkin, Amar Gajjar, Jan O Korbel, Stefan M Pfister
BACKGROUND: Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma predisposition genes have not been defined and screening guidelines for genetic counselling and testing for paediatric patients are not available. We aimed to assess and define these genes to provide evidence for future screening guidelines. METHODS: In this international, multicentre study, we analysed patients with medulloblastoma from retrospective cohorts (International Cancer Genome Consortium [ICGC] PedBrain, Medulloblastoma Advanced Genomics International Consortium [MAGIC], and the CEFALO series) and from prospective cohorts from four clinical studies (SJMB03, SJMB12, SJYC07, and I-HIT-MED)...
May 9, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29753180/a-work-flow-to-build-and-validate-patient-specific-left-atrium-electrophysiology-models-from-catheter-measurements
#13
Cesare Corrado, Steven Williams, Rashed Karim, Gernot Plank, Mark O'Neill, Steven Niederer
Biophysical models of the atrium provide a physically constrained framework for describing the current state of an atrium and allow predictions of how that atrium will respond to therapy. We propose a work flow to simulate patient specific electrophysiological heterogeneity from clinical data and validate the resulting biophysical models. In 7 patients, we recorded the atrial anatomy with an electroanatomical mapping system (St Jude Velocity); we then applied an S1-S2 electrical stimulation protocol from the coronary sinus (CS) and the high right atrium (HRA) whilst recording the activation patterns using a PentaRay catheter with 10 bipolar electrodes at 12 ± 2 sites across the atrium...
April 27, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29750388/impact-of-ovarian-transposition-before-pelvic-irradiation-on-ovarian-function-among-long-term-survivors-of-childhood-hodgkin-lymphoma-a-report-from-the-st-jude-lifetime-cohort-study
#14
Israel Fernandez-Pineda, Andrew M Davidoff, Lu Lu, Bhaskar N Rao, Carmen L Wilson, D Kumar Srivastava, James L Klosky, Monica L Metzger, Matthew J Krasin, Kirsten K Ness, Ching-Hon Pui, Leslie L Robison, Melissa M Hudson, Charles A Sklar, Daniel M Green, Wassim Chemaitilly
BACKGROUND: We reviewed the effect of ovarian transposition (OT) on ovarian function among long-term survivors of childhood Hodgkin lymphoma (HL) treated with pelvic radiotherapy. PROCEDURE: Female participants (age 18+ years) with HL in the St. Jude Lifetime Cohort Study (SJLIFE) were clinically evaluated for premature ovarian insufficiency (POI) 10 or more years after pelvic radiotherapy. Reproductive history including age at menopause and pregnancy/live births was available on all patients...
May 11, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29748189/pacemaker-cybersecurity-local-experience-with-a-firmware-upgrade
#15
Adrian Baranchuk, Bryce Alexander, Debra Campbell, Sohaib Haseeb, Damian Redfearn, Chris Simpson, Ben Glover
In August 2016, Muddy Waters LLC released a short-sell report outlining potential cybersecurity vulnerabilities in several St. Jude Medical (now Abbott) pacemaker models following a demonstration of a "crash attack" and a "battery drain attack" by vulnerability research firm MedSec.1 The motivation behind the release of this report does not appear to have been focused on patient safety; rather than inform Abbott or the US Food and Drug Administration (FDA) directly, the information was released to the public sector...
May 10, 2018: Circulation
https://www.readbyqxmd.com/read/29748188/factors-influencing-the-decision-to-proceed-to-firmware-upgrades-to-implanted-pacemakers-for-cybersecurity-risk-mitigation
#16
Leslie A Saxon, Niraj Varma, Laurence M Epstein, Leonard I Ganz, Andrew E Epstein
In August 2017, the first major recall for cybersecurity vulnerabilities in pacemakers capable of remote connectivity was released that impacted 465,000 United States patients.1,2 The FDA approved a firmware update designed by the manufacturer of the devices as a remediation (Abbott , formally St. Jude Medical). The recall was in response to the public disclosure of vulnerability by an investment firm and produced in a lab environment that could allow an unauthorized party in close proximity to a patient to impact the performance of the device or modify device settings via radio frequency communication...
May 10, 2018: Circulation
https://www.readbyqxmd.com/read/29746378/acute-encephalitis-syndrome-in-gorakhpur-uttar-pradesh-2016-clinical-and-laboratory-findings
#17
Mahima Mittal, Vijay Bondre, Manoj Murhekar, Hirawati Deval, Winsley Rose, Valsan Philip Verghese, Mahim Mittal, Gajanan Patil, R Sabarinathan, Jeromie Wesley Vivian Thangaraj, K Kanagasabai, John Antony Jude Prakash, Nivedita Gupta, Manish Gupte, Mohan D Gupte
BACKGROUND: Seasonal outbreaks of acute encephalitis syndrome (AES) with high fatality have been occurring in Gorakhpur, Uttar Pradesh, India for several years. We conducted investigations during the 2016 outbreak, to identify the etiology. METHODS: We included 407 hospitalized AES patients with CSF pleocytosis (>5 cells/cmm) in our study. These patients were clinically examined; their blood and CSF samples were collected and investigated for scrub typhus (ST), Japanese encephalitis virus (JEV), dengue virus and spotted fever group of rickettsia (SFGR) by serology and/or PCR...
May 9, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29741274/neurologic-impairments-from-pediatric-low-grade-glioma-by-tumor-location-and-timing-of-diagnosis
#18
Zsila S Sadighi, Elizabeth Curtis, Jennifer Zabrowksi, Catherine Billups, Amar Gajjar, Raja Khan, Ibrahim Qaddoumi
BACKGROUND: The neurologic outcomes of low-grade gliomas (LGGs) according to tumor location and duration of presenting symptoms remain poorly characterized in children. PROCEDURE: We retrospectively reviewed neurologic impairments in 246 pediatric patients with LGGs (88 with optic pathway and midline tumors, 56 with posterior fossa tumors, 52 with cerebral hemisphere tumors, 35 with brainstem tumors, and 15 with spinal cord tumors) who were treated at St. Jude Children's Research Hospital between 1995 and 2005...
May 9, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29739020/how-do-transcatheter-heart-valves-fit-in-mitral-annuloplasty-rings-and-which-combination-can-be-recommended
#19
Roya Ostovar, Ralf-Uwe Kuehnel, Michael Erb, Martin Hartrumpf, Thomas Claus, Robert Haase, Johannes M Albes
BACKGROUND:  Transcatheter heart valve (THV) as valve-in-ring is increasingly used in the mitral position. Semi-rigid rings may serve as a more appropriate scaffold for proper anchoring of a THV as they may change from their oval to a round shape thereby fitting to the implanted THV. METHODS:  One rigid and five semi-rigid rings of four manufacturers, Edwards Physio I and II, Sorin 3D Memo, Medtronic Simulus, and St. Jude Medical (SJM) Saddle and SJM Sequin, with sizes 28 to 36 mm and Edwards Sapien III THV 23, 26, and 29 mm were used...
May 8, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29722855/clinical-research-remote-magnetic-navigation-vs-manually-controlled-catheter-ablation-of-right-ventricular-outflow-tract-arrhythmias-a-retrospective-study
#20
Ayelet Shauer, Lennart J De Vries, Ferdi Akca, Jorge Palazzolo, Mohammed Shurrab, Ilan Lashevsky, Irving Tiong, Sheldon M Singh, David Newman, Tamas Szili-Torok, Eugene Crystal
Aims: Remote magnetic navigation (RMN) is an alternative to manual catheter control (MCC) radiofrequency ablation of right ventricular outflow tract (RVOT) arrhythmias. The data to support RMN approach is limited. We aimed to investigate the clinical and procedural outcomes in a cohort of patients undergoing RVOT premature ventricular complex/ventricular tachycardia (PVCs/VT) ablation procedures using RMN vs. MCC. Methods and results: Data was collected from two centres...
May 1, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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