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https://www.readbyqxmd.com/read/29680298/experimental-evaluation-of-homemade-distal-stent-graft-fenestration-for-thoracic-endovascular-aortic-repair-of-type-a-dissection-by-a-transapical-approach
#1
Thomas Gandet, Anis Seghrouchni, Baris Ata Ozdemir, Guillaume Captier, Roland Demaria, Pierre Alric, Bernard Albat, Ludovic Canaud
OBJECTIVE: The use of off-the-shelf stent grafts for thoracic endovascular aortic repair of type A dissections is limited by variability in both the length of the ascending aorta and the location of the proximal intimal tear. This experimental study aimed to assess the feasibility of using a physician-modified thoracic aortic stent graft to treat acute type A dissection by a transapical cardiac approach. METHODS: The experiments were performed on six cadaveric human heart, ascending aorta, aortic arch, and descending aorta specimens...
April 18, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29668410/case-253-thrombosed-umbilical-venous-varix-in-an-infant
#2
Jesse K Sandberg, Rebecca Hulett-Bowling, Geetika Khanna
History A 3-month-old previously healthy girl presented to an outside institution with a 4-day history of low-grade fever, irritability, and a tender "knot" in the upper abdomen. Ultrasonography (US) was performed at an outside hospital. US images were not available for review; however, they showed a mass in the left hepatic lobe, per the outside report, and the patient was referred to our institution for further evaluation. Her parents reported a normal full-term pregnancy, with regular prenatal care and normal prenatal US findings...
May 2018: Radiology
https://www.readbyqxmd.com/read/29667869/evaluation-of-an-innovative-spinal-cord-stimulator-platform-for-the-treatment-of-chronic-pain
#3
Christopher Davies, Carlee Komoroski, Lance Roy
Spinal cord stimulation (SCS) is an ever-evolving therapy for the treatment of chronic pain. Currently, there are four main companies offering a variety of options for SCS. The Intellis™ system is the latest offering from Medtronic (MN, USA). Intellis offers the smallest implantable SCS pulse generator available and is capable of multiple different modes of stimulation, some of which can be run simultaneously. With an intrinsic accelerometer, the device is capable of sensing various patient positions and can automatically adjust stimulation intensity...
April 18, 2018: Pain Management
https://www.readbyqxmd.com/read/29667015/stent-thrombosis-rates-the-first-year-and-beyond-with-new-and-old-generation-drug-eluting-stents-compared-to-bare-metal-stents
#4
Christoph Varenhorst, Martin Lindholm, Giovanna Sarno, Göran Olivecrona, Ulf Jensen, Johan Nilsson, Jörg Carlsson, Stefan James, Bo Lagerqvist
OBJECTIVES: Old-generation drug-eluting coronary stents (o-DES) have despite being safe and effective been associated with an increased propensity of late stent thrombosis (ST). We evaluated ST rates in o-DES, new-generation DES (n-DES) and bare metal stents (BMS) the first year (< 1 year) and beyond 1 year (> 1 year). METHODS: We evaluated all implantations with BMS, o-DES (Cordis Cypher, Boston Scientific Taxus Liberté and Medtronic Endeavor) and n-DES in the Swedish coronary angiography and angioplasty registry (SCAAR) between 1 January 2007 and 8 January 2014 (n = 207 291)...
April 17, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29656955/from-innovation-to-market-adoption-in-the-operating-room-the-cfo-as-customer
#5
Ryan D Egeland, Zachary Rapp, Frank S David
Dr Egeland is senior director of business development and licensing in the Early Technologies business unit of the Minimally Invasive Therapies Group at Medtronic. Mr Rapp is an associate consultant at Pharmagellan, a biotech consultancy. Dr David is the founder and managing director of Pharmagellan.
September 2017: Surgery
https://www.readbyqxmd.com/read/29628471/a-case-of-a-cardiac-resynchronization-therapy-defibrillator-exhibiting-a-lower-and-alternately-variable-basic-rate
#6
Keigo Iwazaki, Toshiya Kojima, Takahide Murasawa, Jun Yokota, Hikaru Tanimoto, Jun Matsuda, Nobuaki Fukuma, Takumi Matsubara, Yu Shimizu, Gaku Oguri, Eriko Hasumi, Hitoshi Kubo, Kyungho Chang, Katsuhito Fujiu, Issei Komuro
A cardiac resynchronization therapy defibrillator (CRT-D) (Medtronic Inc. Protecta XT) was implanted in a 67-year-old man who had cardiac sarcoidosis with extremely low cardiac function. He had ventricular tachycardia which was controlled by catheter ablation, medication and pacing. The programmed mode was DDI, lower rate was 90 beats/minute, paced AV delay was 150 ms, and the noncompetitive atrial pacing (NCAP) function was programmed as 300 ms.After his admission for pneumonia and heart failure, we changed his DDI mode to a DDD mode because he had atrial tachycardia, which led to inadequate bi-ventricular pacing...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29628466/increase-carotid-flow-by-double-sheath-connection-technique-to-reduce-cerebral-ischemia-for-transcatheter-aortic-valve-implantation-through-transcarotid-approach
#7
Richard Tsai, I-Ming Chen, Po-Lin Chen, Hsin-Bang Leu, Ying-Hwa Chen, Hsiao-Huang Chang
PURPOSE: Transcarotid transcatheter aortic valve implantation (TAVI) is one alternative approach if unfavorable femoral access. However, this approach may cause cerebral vascular accidents (CVAs) by temporarily occluding common carotid artery (CCA). The purpose of this study is to develop a new method reducing cerebral ischemia during transcarotid TAVI. METHODS: We inserted an 8- and 18-Fr. sheath in CCA with tip toward brain and aortic arch, respectively, and connected their side arms to create a bypass flow...
April 6, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29626682/patterns-predictors-and-outcomes-of-post-procedure-delayed-hemorrhage-following-flow-diversion-for-intracranial-aneurysm-treatment
#8
A C White, D A Kumpe, C D Roark, D E Case, J Seinfeld
PURPOSE: To evaluate patterns, predictors, and outcomes of post procedure delayed hemorrhage (PPDH) following flow diversion therapy for intracranial aneurysm. METHODS: 50 patients with 52 aneurysms were treated from 2012-2016 with the Pipeline Embolization Device (PED; Medtronic, Minneapolis, MN). PED placement was performed as a standalone therapy or with adjunctive coil embolization. Patients underwent dual antiplatelet therapy (DAT) for 6 months following treatment...
April 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29616520/comparison-of-endovascular-aneurysm-sealing-and-repair-with-respect-to-contrast-use-and-radiation-in-comparable-patient-cohorts
#9
Andreas S Peters, Johannes Hatzl, Moritz S Bischoff, Dittmar Böckler
BACKGROUND: Due to recent advances in endograft design and percutaneous access, technical success could be increased during endovascular aneurysm repair (EVAR). Beside EVAR, endovascular aneurysm sealing (EVAS) provides an alternative procedure to treat aneurysms. To compare the two methods, additional benchmark criteria should be evaluated: Screening time, dose area product (DAP), procedure time and contrast use. In this study these technical variables are analysed for EVAS vs. EVAR in comparable patient cohorts...
April 3, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29610446/mechanisms-of-lead-failure-by-recall-status-and-manufacturer-results-from-the-pacemaker-and-implantable-defibrillator-leads-survival-study-paidless
#10
Sam N Schwarzwald, Daniel J Kersten, Zohaib A Shaikh, Brandon S Needelman, Alyssa M Feldman, Joseph Germano, Shahidul Islam, Todd J Cohen
OBJECTIVES: The aim of this study was to determine the differences in lead failure mechanisms across the major United States implantable defibrillator lead manufacturers (Boston Scientific, Medtronic, and St. Jude Medical), between all non-recalled and recalled leads, and between two recalled lead families (Medtronic Sprint Fidelis and the St. Jude Medical Riata and Riata ST). METHODS: This was a single-center, non-randomized, retrospective study analyzing 3802 patients with 4078 leads who underwent implantable defibrillator lead implantation between February 1, 1996 and December 31, 2011...
April 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29608747/pharmacy-mediated-antiplatelet-management-protocol-compared-to-one-time-platelet-function-testing-prior-to-pipeline-embolization-of-cerebral-aneurysms-a-propensity-score-matched-cohort-study
#11
Christoph J Griessenauer, Abhi Jain, Alejandro Enriquez-Marulanda, Raghav Gupta, Nimer Adeeb, Justin M Moore, Stacey A Grassi, Shamsher S Dalal, Christopher S Ogilvy, Ajith J Thomas, Clemens M Schirmer
BACKGROUND: There is ongoing controversy regarding the optimal antiplatelet regimen, and extent or even need for platelet function testing surrounding Pipeline flow diverter (Medtronic Inc, Dublin, Ireland) embolization of cerebral aneurysms. OBJECTIVE: To compare a unique pharmacy-mediated antiplatelet medication management protocol to a 1-time platelet function testing strategy prior to Pipeline placement. METHODS: A retrospective review of patients with cerebral aneurysms who underwent Pipeline embolization at 2 academic institutions was performed...
March 27, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29608702/flow-diversion-of-posterior-circulation-cerebral-aneurysms-a-single-institution-series-of-59-cases
#12
Matthew T Bender, Geoffrey P Colby, Bowen Jiang, Li-Mei Lin, Jessica K Campos, Risheng Xu, Erick M Westbroek, Chau D Vo, David A Zarrin, Justin M Caplan, Judy Huang, Rafael J Tamargo, Alexander L Coon
BACKGROUND: Posterior circulation cerebral aneurysms are at higher risk of rupture and are more symptomatic than those in the anterior circulation. Existing treatments carry significant morbidity. Early reports of flow diversion for posterior circulation aneurysms have suggested high complication and low occlusion rates. OBJECTIVE: To report safety and efficacy of flow diversion with the pipeline embolization device (ev3, Medtronic Inc, Dublin, Ireland) for aneurysms located throughout the posterior circulation...
March 28, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29599379/comparison-of-general-anaesthesia-and-non-general-anaesthesia-approach-in-transfemoral-transcatheter-aortic-valve-implantation
#13
Mehdi Eskandari, Omar Aldalati, Rafal Dworakowski, Jonathan A Byrne, Emma Alcock, Olaf Wendler, Philip A MacCarthy, Peter F Ludman, David J R Hildick-Smith, Mark J Monaghan
OBJECTIVE: Performing transfemoral transcatheter aortic valve implantation (TAVI) without general anaesthesia (GA) has been increasingly adopted. We sought to study the impact of GA and non-GA approaches on procedural outcome and 30-day and 1-year mortality in transfemoral TAVI. METHODS: The UK TAVI registry holds information for every TAVI procedure in the UK. We analysed the data for patients implanted during 2013-2014 using either an Edwards Sapien or a Medtronic CoreValve prosthesis...
March 29, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29590714/manual-intracardiac-electrogram-method-is-accurate-alternative-to-echocardiography-for-atrioventricular-and-interventricular-optimization-in-cardiac-resynchronization-therapy
#14
Borka Pezo Nikolić, Daniel Lovrić, Jana Ljubas Maček, Vlatka Rešković Lukšić, Richard Matasić, Jadranka Šeparović Hanževački
Some manufacturers do not provide automated intracardiac electrogram method (IEGM) systems for atrioventricular (AV) and interventricular (VV) delay optimization in cardiac resynchronization therapy (CRT). We aimed to evaluate the accuracy of manual IEGM method in 48 patients previously implanted with Medtronic Syncra CRT. All patients underwent standard device interrogation followed by CRT optimization by IEGM method and by echocardiography one month after implantation. The patient mean age was 60.7±11.8 years and there were 33 (68...
December 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29590420/on-pump-transapical-cardioscopic-mitral-valve-replacement-with-cardiac-arrest-short-term-results-in-a-porcine-survival-model
#15
Thang Duc Vu, Duc-Viet Nguyen, Min Zin Oo, Mohamed Alaa, Ervin Marquez Ocampo, Suganya Cheyyatraivendran Arularasu, Phyo Wai Win, Nurdiyana Ja'afar, Goh Si-Guim, Patsy Ong, Lian Kah Ti, Arthur Mark Richards, Theo Kofidis
OBJECTIVES: Favourable outcomes with mitral annuloplasty have been achieved with transapical cardioscopic (TAC) surgery in a survival animal model. In addition, experimental TAC on a non-survival animal model also showed adequate access to remove the native mitral valve and implant a prosthetic valve, but the surgical procedure took a long time and lacked follow-up data. The goal of this study was to develop a clinically translatable TAC mitral valve replacement (MVR) procedure using technical and instrumental refinements to reduce the surgical time and to evaluate functional recovery and short-term durability using a survival porcine model...
March 26, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29579171/a-comparison-of-early-redo-surgery-rates-in-mosaic-porcine-and-perimount-bovine-pericardial-valves
#16
Jessica Webb, Denise Parkin, Kristin Tøndel, Panagiotis Simitsis, James Roxburgh, John B Chambers
OBJECTIVES: The objective of this study was to compare rates of redo surgery for the Medtronic Mosaic 305 A Porcine Prosthesis and the Carpentier-Edwards Perimount Pericardial Aortic Bioprosthesis 2900. METHODS: This was a single-centre retrospective observational study. We included all 1018 patients who underwent aortic valve replacement with a Mosaic (n = 216) or Perimount (n = 809) bioprosthesis between October 2000 and August 2008. The total follow-up was 1508 patient-years for the Mosaic valve and 5813 for the Perimount valve...
March 20, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29566801/transcatheter-pulmonary-valve-replacement-with-the-melody-valve-in-small-diameter-expandable-right-ventricular-outflow-tract-conduits
#17
Shabana Shahanavaz, Athar M Qureshi, Daniel S Levi, Younes Boudjemline, Lynn F Peng, Mary Hunt Martin, Holly Bauser-Heaton, Britton Keeshan, Jeremy D Asnes, Thomas K Jones, Henri Justino, Jamil A Aboulhosn, Robert G Gray, Hoang Nguyen, David T Balzer, Doff B McElhinney
OBJECTIVES: This study sought to evaluate the safety, feasibility, and outcomes of transcatheter pulmonary valve replacement (TPVR) in conduits ≤16 mm in diameter. BACKGROUND: The Melody valve (Medtronic, Minneapolis, Minnesota) is approved for the treatment of dysfunctional right ventricular outflow tract (RVOT) conduits ≥16 mm in diameter at the time of implant. Limited data are available regarding the use of this device in smaller conduits. METHODS: The study retrospectively evaluated patients from 9 centers who underwent percutaneous TPVR into a conduit that was ≤16 mm in diameter at the time of implant, and reported procedural characteristics and outcomes...
March 26, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29565722/sensor-augmented-pump-based-customized-mathematical-model-for-type-1-diabetes
#18
Benyamin Grosman, Di Wu, Diana Miller, Louis Lintereur, Anirban Roy, Neha Parikh, Francine R Kaufman
BACKGROUND: Simulations using mathematical models are important for studying, developing, and improving therapies for people with type 1 diabetes. METHODS: The Medtronic CareLink® database was used to create virtual patients with a variety of inter-insulin sensitivities, meal absorption rates, pharmacokinetics, age, and gender. In addition, intra-insulin sensitivities of the virtual patients change over a 24-h cycle. RESULTS: A total of 2087 virtual patients were developed...
March 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29555535/anatomical-and-procedural-determinants-of-ambulatory-blood-pressure-lowering-following-catheter-based-renal-denervation-using-radiofrequency
#19
Lucas Lauder, Sebastian Ewen, Abraham R Tzafriri, Elazer R Edelman, Bodo Cremers, Saarraaken Kulenthiran, Christian Ukena, Dominik Linz, Ingrid Kindermann, Costas Tsioufis, Bruno Scheller, Michael Böhm, Felix Mahfoud
BACKGROUND/PURPOSE: Catheter-based renal sympathetic denervation (RDN) has been introduced to lower blood pressure (BP) and sympathetic activity in patients with uncontrolled hypertension with at best equivocal results. It has been postulated that anatomic and procedural elements introduce unaccounted variability and yet little is known of the impact of renal anatomy and procedural parameters on BP response to RDN. METHODS/MATERIALS: Anatomical parameters such as length and diameter were analyzed by quantitative vascular analysis and the prevalence of accessory renal arteries and renal artery disease were documented in 150 patients with resistant hypertension undergoing bilateral RDN using a mono-electrode radiofrequency catheter (Symplicity Flex, Medtronic)...
March 2, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29554309/the-surgical-approach-to-the-anterior-nucleus-of-thalamus-in-patients-with-refractory-epilepsy-experience-from-the-international-multicenter-registry-more
#20
Kai Lehtimäki, Volker A Coenen, Antonio Gonçalves Ferreira, Paul Boon, Christian Elger, Rod S Taylor, Philippe Ryvlin, Antonio Gil-Nagel, Frans Gielen, Thomas C Brionne, Abdallah Abouihia, Grégory Beth
BACKGROUND: The Medtronic Registry for Epilepsy (MORE; Medtronic Inc, Dublin, Ireland) is an open label observational study evaluating the long-term effectiveness, safety, and performance of deep brain stimulation (DBS) of the anterior nucleus of thalamus (ANT) for the treatment of refractory epilepsy. OBJECTIVE: To compare the difference in success rate of placing contacts at ANT-target region (ANT-TR) between transventricular (TV) and extraventricular (EV) lead trajectories in 73 ANT-DBS implants in 17 European centers participating in the MORE registry...
March 15, 2018: Neurosurgery
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