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Sensory integration disorder

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https://www.readbyqxmd.com/read/28632204/successful-pharmacotherapy-for-the-treatment-of-severe-feeding-aversion-with-mechanistic-insights-from-cross-species-neuronal-remodeling
#1
W G Sharp, A G Allen, K H Stubbs, K K Criado, R Sanders, C E McCracken, R G Parsons, L Scahill, S L Gourley
Pediatric feeding disorders affect up to 5% of children, causing severe food intake problems that can result in serious medical and developmental outcomes. Behavioral intervention (BI) is effective in extinguishing feeding aversions, and also expert-dependent, time/labor-intensive and not well understood at a neurobiological level. Here we first conducted a double-blind, placebo-controlled trial comparing BI with BI plus d-cycloserine (DCS). DCS is a partial N-methyl-d-aspartate (NMDA) receptor agonist shown to augment extinction therapies in multiple anxiety disorders...
June 20, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28631858/sensory-response-in-host-and-engrafted-astrocytes-of-adult-brain-in-vivo
#2
REVIEW
Kuan Zhang, Xiaowei Chen
Rapid advances in Ca(2+) imaging techniques enable us to simultaneously monitor the activities of hundreds of astrocytes in the intact brain, thus providing a powerful tool for understanding the functions of both host and engrafted astrocytes in sensory processing in vivo. These techniques include both improved Ca(2+) indicators and advanced optical recording methods. Astrocytes in multiple cortical and sub-cortical areas are able to respond to the corresponding sensory modalities. These sensory stimuli produce astrocytic Ca(2+) responses through different cellular mechanisms...
June 20, 2017: Glia
https://www.readbyqxmd.com/read/28630661/intrainsular-connectivity-and-somatosensory-responsiveness-in-young-children-with-asd
#3
Michelle D Failla, Brittany R Peters, Haleh Karbasforoushan, Jennifer H Foss-Feig, Kimberly B Schauder, Brynna H Heflin, Carissa J Cascio
BACKGROUND: The human somatosensory system comprises dissociable paths for discriminative and affective touch, reflected in separate peripheral afferent populations and distinct cortical targets. Differences in behavioral and neural responses to affective touch may have an important developmental role in early social experiences, which are relevant for autism spectrum disorder (ASD). METHODS: Using probabilistic tractography, we compared the structural integrity of white matter pathways for discriminative and affective touch in young children with ASD and their typically developing (TD) peers...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28621219/manualization-of-occupational-therapy-using-ayres-sensory-integration%C3%A2-for-autism
#4
Joanne Hunt, Elke van Hooydonk, Patricia Faller, Zoe Mailloux, Roseann Schaaf
This article reports on the development of a Stage 3 manual (following pilot effectiveness study) for implementing occupational therapy using Ayres Sensory Integration® (OT/ASI) for children with autism spectrum disorders to enhance participation in daily occupations. Three stakeholder groups were surveyed to aid in translation of manual from research to practice (i.e., Stage 3 manual) and an expert consensus meeting was held to finalize recommendations. Data indicated that the manuals usability could be improved by including a section on frequently encountered problems and solutions, and by including video case examples...
July 2017: OTJR: Occupation, Participation and Health
https://www.readbyqxmd.com/read/28608175/reliability-and-validity-of-clinical-tests-to-assess-the-anatomical-integrity-of-the-cervical-spine-in-adults-with-neck-pain-and-its-associated-disorders-part-1-a-systematic-review-from-the-cervical-assessment-and-diagnosis-research-evaluation-cadre-collaboration
#5
REVIEW
Nadège Lemeunier, S da Silva-Oolup, N Chow, D Southerst, L Carroll, J J Wong, H Shearer, P Mastragostino, J Cox, E Côté, K Murnaghan, D Sutton, P Côté
OBJECTIVE: To determine the reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. METHODS: We updated the systematic review of the 2000-2010 Bone and Joint Decade Task Force on Neck Pain and its Associated Disorders. We also searched the literature to identify studies on the reliability and validity of Doppler velocimetry for the evaluation of cervical arteries. Two independent reviewers screened and critically appraised studies...
June 12, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28601369/body-representation-difficulties-in-children-and-adolescents-with-autism-may-be-due-to-delayed-development-of-visuo-tactile-temporal-binding
#6
Danielle Ropar, Katie Greenfield, Alastair D Smith, Mark Carey, Roger Newport
Recent research suggests visuo-tactile binding is temporally extended in autism spectrum disorders (ASD), although it is not clear whether this specifically underlies altered body representation in this population. In the current study children and adolescents with ASD, and typically developing controls, placed their hand into mediated reality system (MIRAGE) and saw two identical live video images of their own right hand. One image was in the proprioceptively correct location (veridical hand) and the other was displaced to either side...
April 27, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28592687/efferent-inhibition-strength-is-a-physiological-correlate-of-hyperacusis-in-children-with-autism-spectrum-disorder
#7
Uzma S Wilson, Kate M Sadler, Kenneth E Hancock, John J Guinan, Jeffery T Lichtenhan
Autism spectrum disorder (ASD) is a developmental disability that is poorly understood. ASD can influence communication, social interaction, and behavior. Children with ASD often have sensory hypersensitivities, including auditory hypersensitivity (hyperacusis). In adults with hyperacusis who are otherwise neurotypical, the medial olivocochlear (MOC) efferent reflex is stronger than usual. In children with ASD the MOC reflex has been measured, but without also assessing hyperacusis. We assessed the MOC reflex in children with ASD by measuring the strength of MOC-induced inhibition of transient-evoked otoacoustic emissions (TEOAEs), a non-invasive, physiological measure that reflects cochlear amplification...
June 7, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28562287/interventions-targeting-sensory-challenges-in-autism-spectrum-disorder-a-systematic-review
#8
REVIEW
Amy S Weitlauf, Nila Sathe, Melissa L McPheeters, Zachary E Warren
CONTEXT: Sensory challenges are common among children with autism spectrum disorder (ASD). OBJECTIVE: To evaluate the effectiveness and safety of interventions targeting sensory challenges in ASD. DATA SOURCES: Databases, including Medline and PsycINFO. STUDY SELECTION: Two investigators independently screened studies against predetermined criteria. DATA EXTRACTION: One investigator extracted data with review by a second...
May 26, 2017: Pediatrics
https://www.readbyqxmd.com/read/28553606/endocrine-glands-and-hearing-auditory-manifestations-of-various-endocrine-and-metabolic-conditions
#9
REVIEW
Kripa Elizabeth Cherian, Nitin Kapoor, Suma Susan Mathews, Thomas Vizhalil Paul
The aetiology of hearing loss in humans is multifactorial. Besides genetic, environmental and infectious causes, several endocrine and metabolic abnormalities are associated with varying degrees of hearing impairment. The pattern of hearing loss may be conductive, sensori-neural or mixed. The neurophysiology of hearing as well as the anatomical structure of the auditory system may be influenced by changes in the hormonal and metabolic milieu. Optimal management of these conditions requires the integrated efforts of the otolaryngologist and the endocrinologist...
May 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28545994/the-impact-of-atypical-sensory-processing-on-social-impairments-in-autism-spectrum-disorder
#10
REVIEW
Melissa D Thye, Haley M Bednarz, Abbey J Herringshaw, Emma B Sartin, Rajesh K Kana
Altered sensory processing has been an important feature of the clinical descriptions of autism spectrum disorder (ASD). There is evidence that sensory dysregulation arises early in the progression of ASD and impacts social functioning. This paper reviews behavioral and neurobiological evidence that describes how sensory deficits across multiple modalities (vision, hearing, touch, olfaction, gustation, and multisensory integration) could impact social functions in ASD. Theoretical models of ASD and their implications for the relationship between sensory and social functioning are discussed...
May 17, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28536959/multisensory-integration-of-low-level-information-in-autism-spectrum-disorder-measuring-susceptibility-to-the-flash-beep-illusion
#11
Vanessa A Bao, Victoria Doobay, Laurent Mottron, Olivier Collignon, Armando Bertone
Previous studies have suggested audiovisual multisensory integration (MSI) may be atypical in Autism Spectrum Disorder (ASD). However, much of the research having found an alteration in MSI in ASD involved socio-communicative stimuli. The goal of the current study was to investigate MSI abilities in ASD using lower-level stimuli that are not socio-communicative in nature by testing susceptibility to auditory-guided visual illusions. Adolescents and adults with ASD and typically-developing (TD) individuals were shown to have similar susceptibility to a fission illusion...
May 23, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28528227/treatment-non-response-associations-with-smoking-expectancies-among-treatment-seeking-smokers
#12
Lorra Garey, Samar A Taha, Brooke Y Kauffman, Kara F Manning, Clayton Neighbors, Norman B Schmidt, Michael J Zvolensky
Despite the high rate of smoking cessation treatment non-response, relatively little empirical work has examined predictors of treatment non-response. The present study sought to explore the effect of smoking outcome expectancies on treatment response in a sample of treatment-seeking adult daily smokers (N=182; 53.3% female; Mage=40.67; SD=13.63). Results indicated that expectancies for smoking to reduce negative affect were related to an increased likelihood of treatment non-response (OR=0.73, CI: 0.54, 0...
May 9, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28525601/too-fast-or-too-slow-time-and-neuronal-variability-in-bipolar-disorder-a-combined-theoretical-and-empirical-investigation
#13
Georg Northoff, Paola Magioncalda, Matteo Martino, Hsin-Chien Lee, Ying-Chi Tseng, Timothy Lane
Time is an essential feature in bipolar disorder (BP). Manic and depressed BP patients perceive the speed of time as either too fast or too slow. The present article combines theoretical and empirical approaches to integrate phenomenological, psychological, and neuroscientific accounts of abnormal time perception in BP. Phenomenology distinguishes between perception of inner time, ie, self-time, and outer time, ie, world-time, that desynchronize or dissociate from each other in BP: inner time speed is abnormally slow (as in depression) or fast (as in mania) and, by taking on the role as default-mode function, impacts and modulates the perception of outer time speed in an opposite way, ie, as too fast in depression and too slow in mania...
May 19, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28516967/body-worn-triaxial-accelerometer-coherence-and-reliability-related-to-static-posturography-in-unilateral-vestibular-failure
#14
M Alessandrini, A Micarelli, A Viziano, I Pavone, G Costantini, D Casali, F Paolizzo, G Saggio
Since changes in vestibular function may be one cause of disequilibrium, major advances in measuring postural control and sensory integration in vestibular impairments have been achieved by using posturography. However, in order to overcome problems related to this type of technology, body-worn accelerometers (ACC) have been proposed as a portable, low-cost alternative to posturography for measurements of postural sway in a friendly and ecologic environment. Due to the fact that no study to date has shown the experimental validity of ACC-based measures of body sway with respect to posturography for subjects with vestibular deficits, the aim of the present study was: i) to develop and validate a practical tool that can allow clinicians to measure postural sway derangements in an otoneurological setting by ACC, and ii) to provide reliable, sensitive and accurate automatic analysis of sway that could help in discriminating unilateral vestibular failure (UVF) patients...
June 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28511484/efficacy-of-structured-yoga-intervention-for-sleep-gastrointestinal-and-behaviour-problems-of-asd-children-an-exploratory-study
#15
Kumar Narasingharao, Balaram Pradhan, Janardhana Navaneetham
INTRODUCTION: Autism Spectrum Disorder (ASD) is a neuro developmental disorder which appears at early childhood age between 18 and 36 months. Apart from behaviour problems ASD children also suffer from sleep and Gastrointestinal (GI) problems. Major behaviour problems of ASD children are lack of social communication and interaction, less attention span, repetitive and restrictive behaviour, lack of eye to eye contact, aggressive and self-injurious behaviours, sensory integration problems, motor problems, deficiency in academic activities, anxiety and depression etc...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28505985/upper-limb-robotics-applied-to%C3%A2-neurorehabilitation-an-overview-of%C3%A2-clinical-practice
#16
Christophe Duret, Stefano Mazzoleni
BACKGROUND: During the last two decades, extensive interaction between clinicians and engineers has led to the development of systems that stimulate neural plasticity to optimize motor recovery after neurological lesions. This has resulted in the expansion of the field of robotics for rehabilitation. Studies in patients with stroke-related upper-limb paresis have shown that robotic rehabilitation can improve motor capacity. However, few other applications have been evaluated (e.g. tremor, peripheral nerve injuries or other neurological diseases)...
May 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28502070/sleep-in-children-with-autism-spectrum-disorder
#17
REVIEW
Margaret C Souders, Stefanie Zavodny, Whitney Eriksen, Rebecca Sinko, James Connell, Connor Kerns, Roseann Schaaf, Jennifer Pinto-Martin
The purposes of this paper are to provide an overview of the state of the science of sleep in children with autism spectrum disorder (ASD), present hypotheses for the high prevalence of insomnia in children with ASD, and present a practice pathway for promoting optimal sleep. Approximately two thirds of children with ASD have chronic insomnia, and to date, the strongest evidence on promoting sleep is for sleep education, environmental changes, behavioral interventions, and exogenous melatonin. The Sleep Committee of the Autism Treatment Network (ATN) developed a practice pathway, based on expert consensus, to capture best practices for screening, identification, and treatment for sleep problems in ASD in 2012...
June 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28499299/-current-diagnostic-procedures-for-diagnosing-vertigo-and-dizziness
#18
Leif Erik Walther
Modern diagnostic methods such as video head impulse test and cervical and ocular vestibular evoked myogenic potentials allow to measure canal and otolith function quantitatively and objectively. These methods contribute to a complex assessment of the functional integrity of all 5 sensory elements of the vestibular organ for the first time. Moreover, in combination with additional vestibular tests frequency specific and time depended changes of impairments of vestibular sensors and their pathways can be assessed...
April 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28485725/sensory-integration-deficits-support-a-dimensional-view-of-psychosis-and-are-not-limited-to-schizophrenia
#19
O Carter, D Bennett, T Nash, S Arnold, L Brown, R Y Cai, Z Allan, A Dluzniak, K McAnally, D Burr, S Sundram
Visual dysfunction is commonplace in schizophrenia and occurs alongside cognitive, psychotic and affective symptoms of the disorder. Psychophysical evidence suggests that this dysfunction results from impairments in the integration of low-level neural signals into complex cortical representations, which may also be associated with symptom formation. Despite the symptoms of schizophrenia occurring in a range of disorders, the integration deficit has not been tested in broader patient populations. Moreover, it remains unclear whether such deficits generalize across other sensory modalities...
May 9, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28456569/neural-correlates-of-cognitive-control-in-gambling-disorder-a-systematic-review-of-fmri-studies
#20
REVIEW
Lorenzo Moccia, Mauro Pettorruso, Franco De Crescenzo, Luisa De Risio, Luigi di Nuzzo, Giovanni Martinotti, Angelo Bifone, Luigi Janiri, Marco Di Nicola
Decreased cognitive control over the urge to be involved in gambling activities is a core feature of Gambling Disorder (GD). Cognitive control can be differentiated into several cognitive sub-processes pivotal in GD clinical phenomenology, such as response inhibition, conflict monitoring, decision-making, and cognitive flexibility. This article aims to systematically review fMRI studies, which investigated the neural mechanisms underlying diminished cognitive control in GD. We conducted a comprehensive literature search and collected neuropsychological and neuroimaging data investigating cognitive control in GD...
July 2017: Neuroscience and Biobehavioral Reviews
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