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Tic disorders

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https://www.readbyqxmd.com/read/28202705/moderators-and-predictors-of-response-to-behavior-therapy-for-tics-in-tourette-syndrome
#1
Denis G Sukhodolsky, Douglas W Woods, John Piacentini, Sabine Wilhelm, Alan L Peterson, Lily Katsovich, James Dziura, John T Walkup, Lawrence Scahill
OBJECTIVE: To examine moderators and predictors of response to behavior therapy for tics in children and adults with Tourette syndrome and chronic tic disorders. METHODS: Data from 2 10-week, multisite studies (1 in children and 1 in adults; total n = 248) comparing comprehensive behavioral intervention for tics (CBIT) to psychoeducation and supportive therapy (PST) were combined for moderator analyses. Participants (177 male, 71 female) had a mean age of 21.5 ± 13...
February 15, 2017: Neurology
https://www.readbyqxmd.com/read/28183397/impact-of-anxiety-and-or-depressive-disorders-and-chronic-somatic-diseases-on-disability-and-work-impairment
#2
Wicher A Bokma, Neeltje M Batelaan, Anton J L M van Balkom, Brenda W J H Penninx
OBJECTIVE: Anxiety and/or Depressive Disorders (ADDs) and Chronic Somatic Diseases (CSDs) are associated with substantial levels of health-related disability and work impairment. However, it is unclear whether comorbid ADDs and CSDs additively affect functional outcomes. This paper examines the impact of ADDs, CSDs, and their comorbidity on disability, work absenteeism and presenteeism. METHODS: Baseline data from the Netherlands Study of Depression and Anxiety (n=2371) were used...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28183072/alternative-therapies-for-excoriation-skin-picking-disorder-a-brief-update
#3
Julio Torales, Iván Barrios, Jorge Villalba
Context • Excoriation (skin picking) disorder is characterized by the need or urge to pick, scratch, pinch, touch, rub, scrub, squeeze, bite, or dig the skin, and it can be a perplexing condition for the inexperienced physician. Treatments include pharmacotherapy, psychotherapy, and alternative therapies. Alternative therapies for excoriation disorder and other body-focused repetitive behaviors include yoga, aerobic exercise, acupuncture, biofeedback, hypnosis, and inositol and N-acetylcysteine, among others...
January 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/28168537/hyperkinetic-movement-disorder-emergencies
#4
REVIEW
Giovanni Cossu, Carlo Colosimo
A movement disorder emergency has been defined by Fahn and Frucht as "any neurological disorder evolving acutely or subacutely, in which the clinical presentation is dominated by a primary movement disorder, and in which failure to accurately diagnose and manage the patient may result in significant morbidity or even mortality." In this review, we discuss the most common situations in which hyperkinetic movement disorders, including chorea, ballism, dystonia, myoclonus, tics, as well as psychogenic disorders, can present as emergencies...
January 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28160010/the-effect-of-sacral-neuromodulation-on-pregnancy-a-systematic-review
#5
Amr Mahran, Alex Soriano, Ahmed S Safwat, Adonis Hijaz, Sangeeta T Mahajan, Emanuel C Trabuco, Steven W Siegel, Sherif A El-Nashar
INTRODUCTION AND HYPOTHESIS: To evaluate the effects of sacral neuromodulation (SNM) on pregnancy and the impact of delivery on SNM function. METHODS: A systematic search was conducted through January 2016. We selected studies including women who had SNM and a subsequent pregnancy. RESULTS: Out of 2,316, eight studies were included, comprising 22 patients (26 pregnancies). SNM indications were Fowler's syndrome in 11, urinary retention in 6, fecal incontinence in 1, fecal and urinary urgency in 1, overactive bladder in 1, intractable interstitial cystitis in 1, and myelodysplasia in 1...
February 3, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28154539/temporal-association-of-certain-neuropsychiatric-disorders-following-vaccination-of-children-and-adolescents-a-pilot-case-control-study
#6
Douglas L Leslie, Robert A Kobre, Brian J Richmand, Selin Aktan Guloksuz, James F Leckman
BACKGROUND: Although the association of the measles, mumps, and rubella vaccine with autism spectrum disorder has been convincingly disproven, the onset of certain brain-related autoimmune and inflammatory disorders has been found to be temporally associated with the antecedent administration of various vaccines. This study examines whether antecedent vaccinations are associated with increased incidence of obsessive-compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28151703/the-child-behavior-checklist-obsessive-compulsive-subscale-detects-severe-psychopathology-and-behavioral-problems-among-school-aged-children
#7
Laura O Saad, Maria C do Rosario, Raony C Cesar, Marcelo C Bastituzzo, Marcelo Q Hoexter, Gisele G Manfro, Roseli G Shavitt, James F Leckman, Eurípedes C Miguel, Pedro G Alvarenga
OBJECTIVE: The aims of this study were (1) to assess obsessive-compulsive symptoms (OCS) dimensionally in a school-aged community sample and to correlate them with clinical and demographical variables; (2) to determine a subgroup with significant OCS ("at-risk for OCD") using the Child Behavior Checklist (CBCL-OCS) and (3) to compare it with the rest of the sample; (4) To review the CBCL-OCS subscale properties as a screening tool for pediatric OCD. METHODS: Data from the Brazilian High Risk Cohort were analyzed...
February 2, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28150698/gilles-de-la-tourette-syndrome
#8
REVIEW
Mary M Robertson, Valsamma Eapen, Harvey S Singer, Davide Martino, Jeremiah M Scharf, Peristera Paschou, Veit Roessner, Douglas W Woods, Marwan Hariz, Carol A Mathews, Rudi Črnčec, James F Leckman
Gilles de la Tourette syndrome (GTS) is a childhood-onset neurodevelopmental disorder that is characterized by several motor and phonic tics. Tics usually develop before 10 years of age, exhibit a waxing and waning course and typically improve with increasing age. A prevalence of approximately 1% is estimated in children and adolescents. The condition can result in considerable social stigma and poor quality of life, especially when tics are severe (for example, with coprolalia (swearing tics) and self-injurious behaviours) or when GTS is accompanied by attention-deficit/hyperactivity disorder, obsessive-compulsive disorder or another neuropsychiatric disorder...
February 2, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28132042/-reasons-and-consequences-of-somatoform-disorders-in-children-and-adolescents
#9
M Khundadze, N Geladze, R Mkheidze, N Khachapuridze, S Bakhtadze
The aim of our study was to find the reason of various forms of somatoform disorders (phobias, behavioral disorders, insomnia, tics, stuttering, enuresis, encopresis) in children and adolescents of various social status for diagnosis and treatment. We have examined 202 patients who referred to our clinic from 2012-2016. The age range was 2-18 years. After examination we have concluded the following recommendations: - to implement neuropsychological rehabilitation in order to stimulate mental development; - to work with speech therapist to improvement the speech; - to work individually with psychotherapist to improve the behavior; - to train the parent to manage the behavior at home; - to give the personal card containing information about exercises, games and puzzles to stimulate the development and in some cases to give individual educational program; - to give separate information to parents and in some cases to teachers of kindergartens and schools...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28117842/histamine-h3r-receptor-activation-in-the-dorsal-striatum-triggers-stereotypies-in-a-mouse-model-of-tic-disorders
#10
M Rapanelli, L Frick, V Pogorelov, H Ohtsu, H Bito, C Pittenger
Tic disorders affect ~5% of the population and are frequently comorbid with obsessive-compulsive disorder, autism, and attention deficit disorder. Histamine dysregulation has been identified as a rare genetic cause of tic disorders; mice with a knockout of the histidine decarboxylase (Hdc) gene represent a promising pathophysiologically grounded model. How alterations in the histamine system lead to tics and other neuropsychiatric pathology, however, remains unclear. We found elevated expression of the histamine H3 receptor in the striatum of Hdc knockout mice...
January 24, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28116741/comorbid-psychiatric-disorders-in-children-and-adolescents-with-nocturnal-enuresis
#11
Shahrokh Amiri, Ali Reza Shafiee-Kandjani, Roghayeh Naghinezhad, Sara Farhang, Salman Abdi
PURPOSE: The present study was conducted with the aim of identifying the frequency of comorbid psychiatricdisorders in children and adolescents with nocturnal enuresis (NE). MATERIALS AND METHODS: In this descriptive-analytical study, 183 children and adolescents aged 5-18 years withNE referred to psychiatric clinics at Tabriz University of Medical Sciences were selected in 2015. A structuredclinical diagnostic interview, the kiddie-schedule for affective disorders and schizophrenia (K-SADS), was employedbased on the diagnostic and statistical manual of mental disorders (DSM-IV-TR) for the diagnosis of NEand comorbid psychiatric disorders...
January 18, 2017: Urology Journal
https://www.readbyqxmd.com/read/28110694/tourette-syndrome-in-the-context-of-evolution-and-behavioral-ecology
#12
Jared Edward Reser
Tourette syndrome, and the closely related spectrum of tic disorders, are inherited neuropsychiatric conditions characterized by the presence of repetitive and stereotyped movements. Tics are elicited by either environmental experiences or internal signals that instruct the basal ganglia to initiate automatic or procedural movements. In most vertebrates the basal ganglia encode instructions for habitually used sequences of motor movements that are essential to survival. Tic disorders may represent evolved phenotypes with a lower threshold for basal ganglia-directed actions...
February 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28104554/abnormalities-in-metabolite-concentrations-in-tourette-s-disorder-and-obsessive-compulsive-disorder-a-proton-magnetic-resonance-spectroscopy-study
#13
Siyan Fan, Danielle C Cath, Odile A van den Heuvel, Ysbrand D van der Werf, Caroline Schöls, Dick J Veltman, Petra J W Pouwels
INTRODUCTION: Abnormal glutamatergic transmission in cortico-striato-thalamo-cortical (CSTC) circuits is thought to be involved in the pathophysiology of Tourette's disorder (TD) and obsessive-compulsive disorder (OCD). Using proton magnetic resonance spectroscopy, the current study aimed to investigate regional concentrations of glutamatergic compounds in TD and OCD patients in comparison to healthy control subjects (HC). MATERIAL AND METHODS: Twenty-three TD patients, 20 OCD patients and 22 HC were included...
January 4, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28099872/assessment-of-gait-and-sensorimotor-deficits-in-the-d1ct-7-mouse-model-of-tourette-syndrome
#14
Stephen C Fowler, Laura J Mosher, Sean C Godar, Marco Bortolato
Tourette syndrome (TS) is a neurodevelopmental disorder characterized by multiple motor and phonic tics. While TS patients have been also shown to exhibit subtle abnormalities of sensorimotor integration and gait, animal models of this disorder are seldom tested for these functions. To fill this gap, we assessed gait and sensorimotor integration in the D1CT-7 mouse, one of the best-validated animal models of TS. D1CT-7 mice exhibit spontaneous tic-like manifestations, which, in line with the clinical phenomenology of TS, are markedly exacerbated by environmental stress...
January 15, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28099039/gilles-de-la-tourette-syndrome-depression-depressive-illness-and-correlates-in-a-child-and-adolescent-population
#15
Renata Rizzo, Mariangela Gulisano, Davide Martino, Mary May Robertson
OBJECTIVE: Gilles de la Tourette syndrome (GTS) and depression are both common disorders. It has been suggested that depression occurs in 13%-76% GTS patients. Despite this, there are few studies into the specific relationships and correlates between the two disorders. There is only some consensus as to the precise relationship between the two disorders. MATERIALS AND METHODS: We undertook the study to investigate the relationship between depressive symptomatology and the core clinical features of GTS in a well-characterized clinical population of youth with this disorder...
January 18, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28094432/maltreatment-associated-neurodevelopmental-disorders-a-co-twin-control-analysis
#16
Lisa Dinkler, Sebastian Lundström, Ruchika Gajwani, Paul Lichtenstein, Christopher Gillberg, Helen Minnis
BACKGROUND: Childhood maltreatment (CM) is strongly associated with psychiatric disorders in childhood and adulthood. Previous findings suggest that the association between CM and psychiatric disorders is partly causal and partly due to familial confounding, but few studies have investigated the mechanisms behind the association between CM and neurodevelopmental disorders (NDDs). Our objective was to determine whether maltreated children have an elevated number of NDDs and whether CM is a risk factor for an increased NDD 'load' and increased NDD symptoms when controlling for familial effects...
January 17, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28093058/off-label-prescribing-of-psychotropic-medication-2005-2013-an-examination-of-potential-influences
#17
Peggy L O'Brien, Nicholas Cummings, Tami L Mark
OBJECTIVE: This study examined rates of psychotropic prescriptions for various on- and off-label uses in 2005 and 2013 in the context of changes in labeled indications. METHODS: The National Disease and Therapeutic Index, a survey of nationally representative office-based physicians that identifies the diagnosis attached to each prescription, was used to capture the number of psychiatric medications prescribed for a particular diagnosis in 2005 (N=4,120) and 2013 (N=4,140)...
January 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28071825/systematic-review-of-severity-scales-and-screening-instruments-for-tics-critique-and-recommendations
#18
Davide Martino, Tamara M Pringsheim, Andrea E Cavanna, Carlo Colosimo, Andreas Hartmann, James F Leckman, Sheng Luo, Alexander Munchau, Christopher G Goetz, Glenn T Stebbins, Pablo Martinez-Martin
BACKGROUND: Several clinician, informant, and self-report instruments for tics and associated phenomena have been developed that differ in construct, comprehensiveness, and ease of administration. OBJECTIVE: A Movement Disorders Society subcommittee aimed to rate psychometric quality of severity and screening instruments for tics and related sensory phenomena. METHODS: Following the methodology adopted by previous Movement Disorders Society subcommittee papers, a review of severity and screening instruments for tics was completed, applying a classification as "recommended," "suggested," or "listed" to each instrument...
January 10, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28039814/specific-executive-control-impairments-in-tourette-syndrome-the-role-of-response-inhibition
#19
Asaf Yaniv, Noa Benaroya-Milshtein, Tamar Steinberg, Dafna Ruhrrman, Alan Apter, Michal Lavidor
BACKGROUND: Tourette syndrome (TS) is a childhood-onset disorder characterized by motor and vocal tics. While cognitive features of common comorbid conditions such as attention deficit hyperactive disorder and obsessive compulsive disorder have been widely investigated, the cognitive profile of TS patients remains to be precisely defined. In this regard, the executive functions system (EF) is of especial interest. AIMS: The aim of the study was to delineate the various components of executive processes in adult TS patients...
December 28, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28038439/revisiting-stigma-exposure-to-tourette-in-an-ordinary-setting-increases-stigmatization
#20
Menachem Ben-Ezra, Sharon Anavi-Goffer, Ella Arditi, Pazit Ron, Rachel Paryenta Atia, Yonat Rate, Krzysztof Kaniasty
Stigma toward people with mental disorders is frequently studied yet less is known about prejudice toward persons with tic disorders, especially sufferers of Gilles de la Tourette Syndrome (GTS). We examined stigmatizing attributions concerning a GTS patient in an online study with participants randomly assigned to one of two video clip conditions: the experimental group saw to a person with Tourette syndrome; the control group watched a nature scenic footage. Results revealed that participants in the experimental condition exhibited higher scores on a stigma questionnaire...
November 29, 2016: Psychiatry Research
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