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CyberKnife

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https://www.readbyqxmd.com/read/28089195/cumulative-volumetric-analysis-as-a-key-criterion-for-the-treatment-of-brain-metastases
#1
Il Kyoon Kim, Robert M Starke, Donald A McRae, Nadim M Nasr, Anthony Caputy, George D Cernica, Robert L Hong, Jonathan H Sherman
BACKGROUND: Recent studies have demonstrated diminished cognitive function, worse quality of life, and no overall survival benefit from the addition of adjuvant whole brain radiation therapy (WBRT) to stereotactic radiosurgery (SRS) in the management of brain metastases. This study analyzes the treatment outcome of SRS, specifically CyberKnife Radiosurgery, based on the total tumor volume compared to the absolute number of lesions. METHODS: A retrospective analysis of hospital records at Virginia Hospital Center for patients with brain metastases who underwent CyberKnife Radiosurgery between June 2008 and June 2014 was performed...
January 11, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28089192/commissioning-monte-carlo-algorithm-for-robotic-radiosurgery-using-cylindrical-3d-array-with-variable-density-inserts
#2
D Dechambre, V Baart, S Cucchiaro, C Ernst, N Jansen, P Berkovic, C Mievis, P Coucke, A Gulyban
INTRODUCTION: To commission the Monte Carlo (MC) algorithm based model of CyberKnife robotic stereotactic system (CK) and evaluate the feasibility of patient specific QA using the ArcCHECK cylindrical 3D-array (AC) with Multiplug inserts (MP). RESULTS: Four configurations were used for simple beam setup and two for patient QA, replacing water equivalent inserts by lung. For twelve collimators (5-60mm) in simple setup, mean (SD) differences between MC and RayTracing algorithm (RT) of the number of points failing the 3%/1mmgamma criteria were 1(1), 1(3), 1(2) and 1(2) for the four MP configurations...
January 11, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28078405/-radiosurgery-and-fractionated-stereotactic-radiotherapy-of-vestibular-schwannoma
#3
K Hamm, H-U Herold, G Surber, S Rosahl
Management of vestibular schwannoma (VS) should always be interdisciplinary and results better than the natural course. Particularly in small VS, either microsurgical resection or radiosurgery (RS) can be employed. RS is a special method (initially only possible stereotactically) for delivering high-precision radiation from many directions to the target point (the isocenter) in a single high dose. With the development of three different systems-Gamma Knife (Elekta, Stockholm, Sweden), special linear accelerators, and CyberKnife (Accuray, Sunnyvale, CA, USA)-the options were extended to 1-5 fractions for RS and multisession RS (msRS), and to up to 6 weeks of conventional fractionation as stereotactic radiotherapy (SRT)...
January 11, 2017: HNO
https://www.readbyqxmd.com/read/28069017/dose-escalation-of-stereotactic-body-radiotherapy-sbrt-for-locally-advanced-unresectable-pancreatic-cancer-patients-with-cyberknife-protocol-of-a-phase-i-study
#4
Shui-Wang Qing, Xiao-Ping Ju, Yang-Sen Cao, Huo-Jun Zhang
BACKGROUND: Dose escalation of SBRT for locally advanced pancreatic cancer patients had been reported in several studies in one or three fractions, and phase I protocol was developed to investigate the maximum tolerated dose with CyberKnife for locally advanced unresectable pancreatic cancer patients in five fractions. METHODS: The study is designed as a mono-center phase I study. The primary endpoint is to determine the maximum tolerated dose by frequency of III/IV GI (gastrointestinal) toxicity...
January 9, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28048550/su-f-t-481-physics-evaluation-of-a-newly-released-incise%C3%A2-multileaf-collimator-for-cyberknife-m6%C3%A2-system
#5
L Wang, E Chin, A Lo
PURPOSE: This work reports the results of the physics evaluation of a newly released InCise™2 Multileaf Collimator (MLC) installed in our institution. METHODS: Beam property data was measured with unshielded diode and EBT2 films. The measurements included MLC leaf transmission, beam profiles, output factors and tissue-phantom ratios. MLC performance was evaluated for one month after commissioning. Weekly Garden Fence tests were performed for leaf / bank positioning in standard (A/P) and clinically relevant non-standard positions, before and after MLC driving exercises of 10+ minutes...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048479/we-ab-207b-01-dose-tolerance-for-sbrt-sabr
#6
J Grimm
PURPOSE: Stereotactic body radiation therapy (SBRT) / stereotactic ablative body radiotherapy (SABR) is gaining popularity, but quantitative dose tolerance has still been lacking. To improve this, the April 2016 issue of Seminars in Radiation Oncology will have normal tissue complication probability (NTCP) models for 10 critical structures: optic pathway, cochlea, oral mucosa, esophagus, chestwall, aorta, bronchi, duodenum, small bowel, and spinal cord. METHODS: The project included more than 1500 treatments in 1-5 fractions using CyberKnife, Gamma Knife, or LINAC, with 60 authors from 15 institutions...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048471/su-g-jep3-03-effect-of-robot-pose-on-beam-blocking-for-ultrasound-guided-sbrt-of-the-prostate
#7
S Gerlach, I Kuhlemann, F Ernst, C Fuerweger, A Schlaefer
PURPOSE: Ultrasound presents a fast, volumetric image modality for real-time tracking of abdominal organ motion. How-ever, ultrasound transducer placement during radiation therapy is challenging. Recently, approaches using robotic arms for intra-treatment ultrasound imaging have been proposed. Good and reliable imaging requires placing the transducer close to the PTV. We studied the effect of a seven degrees of freedom robot on the fea-sible beam directions. METHODS: For five CyberKnife prostate treatment plans we established viewports for the transducer, i...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048418/su-f-sps-10-the-dosimetric-comparison-of-gammaknife-and-cyberknife-treatment-plans-for-brain-srs-treatment
#8
E Sanli, H Mabhouti, M Cebe, G Codel, P Pacaci, E Serin, N Kucuk, E Kucukmorkoc, M Doyuran, D Canoglu, A Altinok, H Acar, H Caglar Ozkok
PURPOSE: Brain stereotactic radiosurgery (SRS) involves the use of precisely directed, single session radiation to create a desired radiobiologic response within the brain target with acceptable minimal effects on surrounding structures or tissues. In this study, the dosimetric comparison of GammaKnife perfection and Cyberknife M6 treatment plans were made. METHODS: Treatment plannings were done for GammaKnife perfection unit using Gammaplan treatment planning system (TPS) on the CT scan of head and neck randophantom simulating the treatment of sterotactic treatments for one brain metastasis...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048402/su-f-t-569-implementation-of-a-patient-specific-qa-method-using-ebt-xd-for-cyberknife-srs-sbrt-plans
#9
K Zerouali, J Aubry, R Doucet
PURPOSE: To implement the new EBT-XD Gafchromic films for accurate dosimetric and geometric validation of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) CyberKnife (CK) patient specific QA. METHODS: Film calibration was performed using a triplechannel film analysis on an Epson 10000XL scanner. Calibration films were irradiated using a Varian Clinac 21EX flattened beam (0 to 20 Gy), to ensure sufficient dose homogeneity. Films were scanned to a resolution of 0...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048379/su-f-t-598-robotic-radiosurgery-system-versus-pencil-beam-scanning-proton-therapy-for-definitive-intracranial-treatments
#10
M Lin, A Pompos, X Gu, Y Yan, R Abdulrahman, R Timmerman, S Jiang
PURPOSE: To characterize the dose distributions of Cyberknife and intensity-modulated-proton-therapy (IMPT). METHODS: A total of 20 patients previously treated with Cyberknife were selected. The original planning-target-volume (PTV) was used in the 'IMPT-ideal' plan assuming a comparable image-guidance with Cyberknife. A 3mm expansion was made to create the proton-PTV for the 'IMPT-3mm' plan representing the current proton-therapy where a margin of 3mm is used to account for the inferior image-guidance...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048317/su-f-t-576-characterization-of-two-dimensional-liquid-filled-detector-array-srs-1000-in-high-precision-cyberknife-robotic-radiosurgery-system
#11
M Muthukumaran, D Manigandan, V Murali, S Vikraman, S Chitra, K Ganapathy
PURPOSE: The aim of the study is to characterize a two dimensional liquid filled detector array SRS 1000 for routine QA in Cyberknife Robotic Radiosurgery system. METHODS: SRS 1000 consists of 977 liquid filled ionization chambers and is designed to be used in small field SRS/SBRT techniques. The detector array has got two different spacial resolutions. Till field size of 5.5×5.5 cm the spacial resolution is 2.5mm (center to center) and after that till field size of 11 × 11 cm the spacial resolution is 5mm...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048315/su-f-t-650-the-comparison-of-robotic-partial-breast-stereotactic-irradiation-using-mlc-vs-iris-cone
#12
C Ding, R Timmerman, S Jiang, A Rahimi
PURPOSE: To evaluate the dosimetric impact on treatment planning for partial breast stereotactic irradiation using Cyberknife with MLC versus Iris Cone. METHODS: Ten patients whom underwent lumpectomy for DCIS or stage I invasive non-lobular epithelial breast cancer were included in this study. All patients were previously treated on the Cyberknife using Iris cone with the prescription dose of 37.5Gy in 5 fractions covering at least 95% of PTV on our phase I SBRT 5 fraction partial breast irradiation trial...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048210/su-g-jep1-10-feasibility-of-cyberknife-tracking-using-the-previously-implanted-permanent-brachytherapy-seed-cloud
#13
J Cheung, J Cunha, A Sudhyadhom, C McGuinness, M Roach, M Descovich
PURPOSE: Robotic radiosurgery is a salvage treatment option for patients with recurrent prostate cancer. We explored the feasibility of tracking the bolus of permanent prostate implants (PPI) using image recognition software optimized to track spinal anatomy. METHODS: Forty-five inert iodine seeds were implanted into a gelatin-based prostate phantom. Four superficial gold seeds were inserted to provide ground-truth alignment. A CT scan of the phantom (120 kVp, 1 mm slice thickness) was acquired and a single-energy iterative metal artifact reduction (MAR) algorithm was used to enhance the quality of the DRR used for tracking...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047954/su-f-t-309-radiochromic-film-calibration-rescaling-for-patient-specific-cyberknife-mlc-qa
#14
T McCaw, S Jang, M Huq
PURPOSE: This work investigated the development of EBT3 film as a function of dose rate, and also the accuracy of a commercial calibrationrescaling analysis method, to determine potential application to patientspecific QA of CyberKnife MLC treatments. METHODS: EBT3 films were exposed to 300cGy at dose rates ranging from 5-300cGy/min, and scanned repeatedly from 2-5760min after exposure using a flatbed scanner. All other films were scanned 1 and 24hr after exposure...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047842/su-f-t-420-dosimetry-comparison-of-advanced-external-beam-radiation-treatment-modalities-to-brachytherapy-treatments-in-patients-with-cervical-cancer
#15
U Mwidu, S Devic, M Shehadeh, M AlKafi, R Mahmood, B Moftah
PURPOSE: A retrospective comparison of dose distributions achievable by High dose rate brachytherapy (HDRBT), Helical TomoTherapy (TOMO), CyberKnife (CK) and RapidArc (RA) in locally advanced inoperable cervical cancer patients is presented. METHODS: Five patients with advanced stage cervical carcinoma were selected for this study after a full course of external beam radiotherapy (EBRT), chemotherapy and HDR Brachytherapy. To highlight any significant similarities/differences in dose distributions, high-risk clinical target volume (HRCTV) coverage, organs at risk (OAR) sparing, and machine specific delivery limitations, we used D90 (dose received by 90% of the volume) as the parameter for HRCTV coverage as recommended by the GEC-ESTRO Working Group...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047829/th-ab-201-07-filmless-treatment-localization-qa-for-the-cyberknife-system
#16
J Gersh, M Noll
PURPOSE: Accuray recommends daily evaluation of the treatment localization and delivery systems (TLS/TDS) of the CyberKnife. The vendor-provided solution is a Winston-Lutz-type test that evaluates film shadows from an orthogonal beam pair (known as AQA). Since film-based techniques are inherently inefficient and potentially inconsistent and uncertain, this study explores a method which provides a comparable test with greater efficiency, consistency, and certainty. This test uses the QAStereoChecker (QASC, Standard Imaging, Inc...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047803/su-f-t-552-a-one-year-evaluation-of-the-qabeamchecker-for-use-with-the-cyberknife-system
#17
J Gersh
PURPOSE: By attaching an adapter plate with fiducial markers to the QA BeamChecker+ (Standard Imaging, Inc., Middleton, WI), the output of the CyberKnife can be accurately, efficiently, and consistently evaluated. The adapter plate, known as the Cutting Board, allows for automated alignment of the QABC+ using the CK's stereoscopic kV image-based treatment localization system (TLS). Described herein is an evaluation of the system following a year of clinical utilization. METHODS: Based on a CT scan of the QABC+ and CB, a treatment plan is generated which delivers a beam to each of the 5 plane-parallel ionization chambers...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047782/we-c-tour-t-00-exhibit-hall-guided-tours-microdosimeters-for-therapy-wednesday-we-c-tour-t-01
#18
(no author information available yet)
Tour Leader: Indra Das, NYU Langone Medical Center, New York, NY Tour Guides: Hsui Ai, Indiana University School of Medicine, Indianapolis, IN Paulina Galvis, NYU Langone Medical Center, New York, NY Olga Volotoskova, NYU Langone Medical Center, New York, NY Participating Vendors: IBA PTW - New York RTI Electronics, Inc. Standard Imaging, Inc. Sun Nuclear Corporation Small fields are increasing used in specialized radiation treatments such as Gammaknife, Cyberknife, Tomotherapy, IMRT, VMAT, SRS and SBRT. Due to small field size electron transport creates lateral electronic disequilibrium and thus dosimetry could be very difficult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047770/su-f-sps-11-the-dosimetric-comparison-of-truebeam-2-0-and-cyberknife-m6-treatment-plans-for-brain-srs-treatment
#19
H Mabhouti, E Sanli, M Cebe, G Codel, P Pacaci, E Serin, N Kucuk, E Kucukmorkoc, M Doyuran, D Canoglu, A Altinok, H Acar, H Caglar Ozkok
PURPOSE: Brain stereotactic radiosurgery involves the use of precisely directed, single session radiation to create a desired radiobiologic response within the brain target with acceptable minimal effects on surrounding structures or tissues. In this study, the dosimetric comparison of Truebeam 2.0 and Cyberknife M6 treatment plans were made. METHODS: For Truebeam 2.0 machine, treatment planning were done using 2 full arc VMAT technique with 6 FFF beam on the CT scan of Randophantom simulating the treatment of sterotactic treatments for one brain metastasis...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047769/su-g-tep2-12-irochouston-and-mdapl-srs-anthropomorphic-phantom-results
#20
A Molineu, S Kry, P Alvarez, N Hernandez, T Nguyen, D Followill
PURPOSE: To report the results of SRS phantom irradiations METHODS: Anthropomorphic SRS head phantoms were sent to institutions participating in NCI sponsored SRS clinical trials and institutions interested in verifying SRS treatment delivery. The phantom shell was purchased from Phantom Laboratory and altered to house dosimetry and imaging inserts. The imaging insert has 1.9 cm diameter spherical target. The dosimetry insert holds two TLD capsules and radiochromic film in the coronal and sagittal planes through the center of the target...
June 2016: Medical Physics
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