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potassium and small bowel obstruction

Dong-Hai Liu, Xu Huang, Xin Guo, Xiang-Min Meng, Yi-Song Wu, Hong-Li Lu, Chun-Mei Zhang, Young-chul Kim, Wen-Xie Xu
Partial obstruction of the small intestine causes obvious hypertrophy of smooth muscle cells and motility disorder in the bowel proximate to the obstruction. To identify electric remodeling of hypertrophic smooth muscles in partially obstructed murine small intestine, the patch-clamp and intracellular microelectrode recording methods were used to identify the possible electric remodeling and Western blot, immunofluorescence and immunoprecipitation were utilized to examine the channel protein expression and phosphorylation level changes in this research...
2014: PloS One
Assanee Tongyoo, Ekkapak Sriussadaporn, Palin Limpavitayaporn, Chatchai Mingmalairak
Sodium polystyrene sulfonate (Kayexalate) and calcium polystyrene sulfonate (CPS, Kalimate) are commonly used to reduce serum potassium. There were some published evidences of severe gastrointestinal complications from the administration of these agents such as colonic necrosis with or without perforation and acute obstruction. The authors reported a 52-year-old male patient being critically ill from severe soft tissue infection of the right leg and sepsis. Hyperkalemia had occurred due to renal insufficiency and required several doses of Kalimate to reduce the serum potassium level...
December 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Fernando Luiz Zanoni, Simon Benabou, Karin Vicente Greco, Ana Carolina Ramos Moreno, José Walber Miranda Costa Cruz, Fernando Paranaiba Filgueira, Marina Baquerizo Martinez, Luiz Francisco Poli de Figueiredo, Maurício Rocha e Silva, Paulina Sannomiya
PURPOSE: Bacterial translocation has been shown to occur in critically ill patients after extensive trauma, shock, sepsis, or thermal injury. The present study investigates mesenteric microcirculatory dysfunctions, the bacterial translocation phenomenon, and hemodynamic/metabolic disturbances in a rat model of intestinal obstruction and ischemia. METHODS: Anesthetized (pentobarbital 50 mg/kg, i.p.) male Wistar rats (250-350 g) were submitted to intestinal obstruction or laparotomy without intestinal obstruction (Sham) and were evaluated 24 hours later...
2009: Clinics
Hans Törnblom, Bethan Lang, Linda Clover, Charles H Knowles, Angela Vincent, Greger Lindberg
OBJECTIVE: Enteric neuropathy with mild inflammation (ganglionitis) has been described in several motility disorders including irritable bowel syndrome (IBS), enteric dysmotility (ED), slow-transit constipation (STC) and chronic intestinal pseudo-obstruction (CIPO). The purpose of this study was to test the hypothesis that autoantibodies directed against specific neural antigens including ion channels may be associated with this finding. MATERIAL AND METHODS: Comprehensive routine and immunohistochemical analyses of full-thickness jejunal laparoscopic biopsies were performed on patients fulfilling the international criteria for IBS, ED, STC and CIPO...
November 2007: Scandinavian Journal of Gastroenterology
Chao-Chin Chao, Yeun Tarl Fresner Ng Jao, Lein-Ray Mo
BACKGROUND AND PURPOSE: Capsule endoscopy (CE) is a new diagnostic modality that is being utilized with increasing frequency for examination of lesions suspected to be of small bowel origin. The most common indication for CE is obscure gastrointestinal bleeding. This study investigated the safety and diagnostic value of CE in patients with obscure gastrointestinal bleeding. METHODS: From February 1 to October 30, 2003, 35 patients with obscure gastrointestinal bleeding among 43 consecutive patients with suspected small bowel pathology were enrolled...
September 2005: Journal of the Formosan Medical Association, Taiwan Yi Zhi
David M Spiro, James M Schmidt, Donald H Arnold, Samuel C Cartner, Aydin Yagmurlu
BACKGROUND: Idiopathic intussusception is a leading cause of intestinal obstruction in young children. Although the etiology remains obscure, lymphoid hyperplasia is found in a majority of cases. Antibiotics, the most frequently prescribed medication class in the pediatric population, have been recently associated with intussusception. The authors sought to determine whether enteral antibiotic exposure influences the development of mesenteric adenopathy, bowel dilation or intussusception in an animal model...
July 2005: Journal of Pediatric Gastroenterology and Nutrition
Monique P Curran, Greg L Plosker
UNLABELLED: Oral sodium phosphate solution (Fleet Phospho-soda, Casen-Fleet Fosfosoda is a low-volume, hyperosmotic agent used as part of a colorectal-cleansing preparation for surgery, x-ray or endoscopic examination. The efficacy and tolerability of oral sodium phosphate solution was generally similar to, or significantly better than, that of polyethylene glycol (PEG) or other colorectal cleansing regimens in patients preparing for colonoscopy, colorectal surgery or other colorectal-related procedures...
2004: Drugs
K E Sullins, N A White, C S Lundin, R Dabareiner, G Gaulin
REASONS FOR PERFORMING STUDY: Treatments addressing variously theorised pathophysiological mechanisms of small intestinal adhesions have been reported. This study applied those classes of treatments to the most clinically relevant aetiology of post operative adhesions. HYPOTHESIS: Treatments addressing the pathophysiology of ischaemia-reperfusion induced adhesions would accordingly reduce the incidence of adhesions from this model. METHODS: Four classes of treatments were administered for 72 h to 16 foals subjected to complete ischaemia followed by reperfusion to create peritoneal adhesions...
July 2004: Equine Veterinary Journal
N Scott Adzick, Paul S Thornton, Charles A Stanley, Robin D Kaye, Eduardo Ruchelli
BACKGROUND/PURPOSE: Congenital hyperinsulinism (HI) causes severe hypoglycemia in neonates and infants. Recessive mutations of the beta-cell K(ATP) channel genes cause diffuse HI, whereas loss of heterozygosity together with inheritance of a paternal mutation cause focal adenomatous HI. Although these 2 forms of HI are clinically identical, focal HI can be cured surgically. The authors reviewed their experience with partial pancreatectomy for focal HI. METHODS: From December 1998 to January 2003, 38 patients (ages 2 weeks to 14 months; median age, 10 weeks) were treated with partial pancreatectomy for focal HI...
March 2004: Journal of Pediatric Surgery
No abstract text is available yet for this article.
September 20, 1965: JAMA: the Journal of the American Medical Association
No abstract text is available yet for this article.
January 23, 1965: Canadian Medical Association Journal
Three cases of intestinal obstruction due to solitary localized ulceration, inflammation and stenosis of the small bowel are described. All three patients had been treated with a pill containing hydrochlorothiazide and an enteric-coated centre of potassium chloride. The occurrence of this lesion in these patients, and in similar cases reported from other centres, suggests that such a combination should not be prescribed.
January 23, 1965: Canadian Medical Association Journal
No abstract text is available yet for this article.
November 16, 1964: JAMA: the Journal of the American Medical Association
Even small losses of gastrointestinal secretions when combined with reduced intake of electrolytes may seriously disturb electrolyte balance. Knowledge of the ionic composition of secretions lost is essential in planning therapy. Loss of gastric contents usually results in excessive loss of chloride; in achlorhydria this is not the case. Loss of sodium and potassium may be large in either case and is often underestimated. Small bowel obstruction results in a more balanced loss of electrolyte which may not affect acidbase balance greatly...
November 1955: California Medicine
H. Demetriades, I. Kanellos, I. Mantzoros, S. Kalfadis, K. Galovatsea, T. Zaraboukas, D. Betsis
PURPOSE: Lanreotide, a long-acting somatostatin analogue, inhibits intestinal, bile and pancreatic secretions and decreases intestinal motility. The purpose of this experimental study was to evaluate the effects of lanreotide on the healing of intestinal anastomoses following small bowel obstruction. METHODS: Two groups of 16 Wistar rats (average weight 310 g) were used. Basal diameters of ileus were measured prior to the ligation of the bowel, 15 cm from the ileocecal valve. Luminal fluid was also withdrawn proximal to the obstructed bowel for sodium and potassium analysis...
January 2002: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
Yuji Kato, Gaku Tamaki, Masayuki Tokumitsu, Satoshi Yamaguchi, Sunao Yachiku, Mitsuhiko Okuyama
We report a case of urolithiasis associated with short bowel syndrome. A 56-year-old woman was admitted to our hospital for asymptomatic bilateral renal stones. She had received extensive resection of small intestine due to strangulating obstructive ileus 7 years ago (residual intestine, only 20 cm). Subsequently, she was in a state of short bowel syndrome. Plain film of kidney, uteter, bladder and computed tomography revealed bilateral renal stones (right 4 mm, left 10 mm). The left renal stone was successfully treated by extracorporeal shock wave lithotripsy...
January 2003: Nihon Hinyōkika Gakkai Zasshi. the Japanese Journal of Urology
V P Petrov, I V Kuznetsov, A A Domnikova
The analysis of 36 case records of patients with peritonitis (n = 12) and intestinal obstruction (n = 24) is presented. Nasogastrointestinal intubation of the small bowel was used in combined treatment. The aims, indications and contraindications for the intubation are formulated. Bacteriologic and biochemical parameters of bowel content were studied. It was established that the quantity of enterobacteria and unfermenting gram-negative bacteria was increased in intestinal paresis, the alkaline phosphatase, amylase, bilirubin, transaminase, a potassium content were increased as well...
1999: Khirurgiia
P Sacher, U G Stauffer
Intestinal lengthening is considered to be one of the most effective surgical interventions to improve the deleterious sequelae of short-bowel syndrome. To assess the efficiency of bowel-lengthening procedures in short-bowel syndrome, an animal model was created in minipigs that show malnutrition, weight loss and small-bowel dilatation. Group 1 consisted of three animals with a 95% distal intestinal resection leaving 15 cm of ileum. Group 2 comprised six animals with a 95% distal intestinal resection leaving only 5 cm of ileum, and group 3 consisted of three animals with a 95% distal intestinal resection leaving 5 cm of ileum and construction of a distal small-bowel stenosis by temporary banding...
August 1997: European Journal of Pediatric Surgery
G R Schmutz, F Chapuis, E Morel, D N'Guyen, C Dion, D Régent
The purpose of this study is to characterize radiographically drug-induced ulcerated stenosis of the small bowel and to determine the contribution of enteroclysis in the diagnosis of this rare entity. The clinical pathologic and radiographic findings of 12 patients with drug-induced stenosis (non steroidal anti-inflammatory drugs or potassium salts) evaluated by enteroclysis were reviewed. Three radiological features of strictures were differentiated: diaphragm like stricture, short stricture and stenotic ulceration with girdle aspect...
January 1997: Journal de Radiologie
S C Yeung, R Go, A Balasubramanyam
We administered potassium iodide and propylthiouracil per rectum, in conjunction with intravenous dexamethasone and propranolol, for emergent treatment of a patient in thyroid storm with small bowel obstruction. Shortly after initiation of this treatment, the patient successfully underwent two emergent surgical procedures for resection of an intestinal volvulus with advanced peritonitis. Serum levels of iodide and propylthiouracil showed substantial absorption of these drugs via the rectal route. Measurement of 24-h urinary-free iodide indicated that the bioavailability of potassium iodide delivered by retention enema was at least 40%...
October 1995: Thyroid: Official Journal of the American Thyroid Association
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