keyword
MENU ▼
Read by QxMD icon Read
search

Approach to a thyroid nodule

keyword
https://www.readbyqxmd.com/read/29770307/which-needle-in-the-treatment-of-thyroid-nodules
#1
REVIEW
Lorenzo Carlo Pescatori, Pierluca Torcia, Luca Nicosia, Giovanni Mauri, Umberto Geremia Rossi, Maurizio Cariati
Thyroid nodules are a common finding in general population, with a prevalence of 20% to 70% at ultrasound (US) examination. Many of them are benign but treatment can be necessary to relief compressive symptoms. In the last years, percutaneous ablations have achieved amazing development in the treatment of thyroid nodules as they provide a minimally invasive but effective approach. We aimed to summarize the main aspects related to treatment of thyroid nodules with radiofrequency ablation (RFA), focusing on the use of different types of needles...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29744655/does-the-acr-ti-rads-scoring-allow-us-to-safely-avoid-unnecessary-thyroid-biopsy-single-center-analysis-in-a-large-cohort
#2
Fatos Dilan Koseoglu Atilla, Basak Ozgen Saydam, Nihat Ali Erarslan, Ayse Gulden Diniz Unlu, Hamiyet Yilmaz Yasar, Muhammet Ozer, Baris Akinci
INTRODUCTION: The American College of Radiology (ACR) has recently proposed a guideline that recommends clinicians to perform thyroid fine-needle aspiration biopsy (FNAB) on the basis of ultrasound features. In this study, we focused on nodules for which no biopsy is recommended by the ACR Thyroid Imaging, Reporting and Data System (TI-RADS) guideline. SUBJECTS AND METHODS: Two-thousand eight-hundred and forty-seven consecutive patients with thyroid nodules who underwent FNAB according to the 2009 American Thyroid Association (ATA) guideline were included...
May 9, 2018: Endocrine
https://www.readbyqxmd.com/read/29733263/hidden-in-plain-sight-transoral-and-submental-thyroidectomy-as-a-compelling-alternative-to-scarless-thyroidectomy
#3
Yufei Chen, Kathryn Chomsky-Higgins, Iheoma Nwaogu, Carolyn D Seib, Jessica E Gosnell, Wen T Shen, Quan-Yang Duh, Insoo Suh
BACKGROUND: Minimally invasive and remote access thyroid surgery has been evolving with the transoral endoscopic thyroidectomy vestibular approach (TOETVA) emerging as a true "scarless" thyroidectomy. In this study, we describe a hybrid transoral and submental thyroidectomy (TOaST) technique for thyroid lobectomy. MATERIALS AND METHODS: A TOaST right thyroid lobectomy was performed for a 4 cm cytologically benign right thyroid nodule. Initial incision was made in the submental region with two additional 5 mm lateral ports inserted transorally...
May 7, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29731981/programmed-death-ligand-1-expression-by-digital-image-analysis-advances-thyroid-cancer-diagnosis-among-encapsulated-follicular-lesions
#4
Anne M-Y Hsieh, Olena Polyakova, Guodong Fu, Ronald S Chazen, Christina MacMillan, Ian J Witterick, Ranju Ralhan, Paul G Walfish
Recognition of noninvasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) that distinguishes them from invasive malignant encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) can prevent overtreatment of NIFTP patients. We and others have previously reported that programmed death-ligand 1 (PD-L1) is a useful biomarker in thyroid tumors; however, all reports to date have relied on manual scoring that is time consuming as well as subject to individual bias. Consequently, we developed a digital image analysis (DIA) protocol for cytoplasmic and membranous stain quantitation (ThyApp) and evaluated three tumor sampling methods [Systemic Uniform Random Sampling, hotspot nucleus, and hotspot nucleus/3,3'-Diaminobenzidine (DAB)]...
April 13, 2018: Oncotarget
https://www.readbyqxmd.com/read/29709542/a-survey-of-current-approaches-to-thyroid-nodules-and-thyroid-operations
#5
Arda Isik, Deniz Firat, Ismayil Yilmaz, Kemal Peker, Oguz Idiz, Bahri Yilmaz, Ismail Demiryilmaz, Fehmi Celebi
INTRODUCTION: Thyroid nodules are commonly seen. Our aim is to learn the behaviors and operational attitudes of surgeons approaching the thyroid nodules. In a literature search, our study is the first and only study performed merely on surgeons. MATERIALS- METODS: This cross-sectional study was done between June 2014-January 2015. The questionnaire consists of 25 questions. Initially, general questions consisting of demographic findings were asked. In step 2, questions consisting of the index case and case variants were asked...
April 27, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29696036/malignancy-rates-in-thyroid-nodules-classified-as-bethesda-categories-iii-and-iv-retrospective-data-from-a-tertiary-center
#6
Beatriz Godoi Cavalheiro, Ana Kober Nogueira Leite, Leandro Luongo de Matos, Aline Palermo Miazaki, Jan Marcel Ientile, Marco Aurelio V Kulcsar, Claudio Roberto Cernea
Background: Thyroid fine needle aspiration (FNA) has a well-established role in the diagnosis of thyroid nodules, and the "Bethesda system for reporting thyroid cytopathology" is used to interpret FNA results. Bethesda categories III and IV encompass varying risks of malignancy. In addition, there is some debate in the literature about how to select among many acceptable treatment approaches. Objectives: To establish an association between these 2 cytological categories and malignancy rates in patients treated in a referral tertiary cancer center, where surgical treatment is recommended for all these patients...
January 2018: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29690556/fine-needle-aspiration-cytology-for-neck-masses-in-childhood-an-illustrative-approach
#7
REVIEW
Consolato Sergi, Aneesh Dhiman, Jo-Ann Gray
The primary indication of fine-needle aspiration cytology of the head and neck region is a thyroid nodule or a mass located in the cervical area or the head. Although a thyroid nodule may raise the suspicion of malignancy, less than one in 20 cases results in a carcinoma. In addition, the list of differential diagnoses is quite different according to the age of the patient. A number of benign lesions, such as branchial cysts, sialadenosis, and sialoadenitis are often seen in childhood and youth. The malignant lesions that are on the top of the list of a pediatric mass of the head and neck (H&N) region include rhabdomyosarcoma, neuroblastoma, and papillary carcinoma of the thyroid gland...
April 22, 2018: Diagnostics
https://www.readbyqxmd.com/read/29684251/image-guided-chemical-and-thermal-ablations-for-thyroid-disease-review-of-efficacy-and-complications
#8
REVIEW
Iain J Nixon, Peter Angelos, Ashok R Shaha, Alessandra Rinaldo, Michelle D Williams, Alfio Ferlito
Image-guided ablation of thyroid disease is increasingly being commonly reported. Techniques including ethanol injection and thermal ablation using radio-frequency, laser, and microwave devices have been described. Minimally invasive approaches to the management of benign cystic, solid, and functional thyroid nodules as well as both primary and recurrent thyroid malignancy have been reported. The purpose of this article is to review the current evidence relating to image-guided ablation of thyroid disease with a focus on clinical outcomes and complication rates for patients treated with this minimally invasive approach...
April 23, 2018: Head & Neck
https://www.readbyqxmd.com/read/29683529/morphology-combined-with-ancillary-techniques-an-algorithm-approach-for-thyroid-nodules
#9
Esther Diana Rossi, Maurizio Martini, Sara Capodimonti, Tonia Cenci, Mirna Bilotta, Francesco Pierconti, Alfredo Pontecorvi, Celestino Pio Lombardi, Guido Fadda, Luigi Maria Larocca
OBJECTIVE: Several authors have underlined the limits of morphological analysis mostly in the diagnosis of follicular neoplasms (FN). The application of ancillary techniques (AT), including immunocytochemistry(ICC) and molecular testing (MT), contributes to a better definition of the risk of malignancy(ROM) and management of FN. According to literature, the application of models, including the evaluation of ICC, somatic mutations (i.e. BRAFV 600E ), miRNA analysis is proposed for FNs...
April 23, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29672887/young-age-is-associated-with-increased-rates-of-residual-recurrent-pediatric-differentiated-thyroid-carcinoma
#10
Sarah Hampson, Derek Stephens, Jonathan D Wasserman
OBJECTIVE: Differentiated thyroid carcinoma is rare in young children. There are conflicting data as to whether disease in this age group differs from that in adolescents and specifically, if it is more aggressive. Current practice guidelines do not differentiate treatment between these groups, but speculate that differences may exist. We sought to compare clinical features, treatment and outcomes between children (<12 years) and adolescents (12-18 years) with thyroid nodules and thyroid malignancy over a 20 year period...
April 19, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29672763/prospective-validation-of-ata-and-eta-sonographic-pattern-risk-of-thyroid-nodules-selected-for-fnac
#11
Fabio Maino, Raffaella Forleo, Martina Martinelli, Noemi Fralassi, Filomena Barbato, Tania Pilli, Marco Capezzone, Lucia Brilli, Cristina Ciuoli, Giovanni Di Cairano, Laura Nigi, Furio Pacini, Maria Grazia Castagna
Background: Recently, the American (ATA) and the European Thyroid Association (ETA), have proposed that thyroid ultrasound (US) should be used to stratify the risk of malignancy in thyroid nodules and to aid decision-making about whether FNAC is indicated. Objective: To validate and to compare the ATA and ETA US risk stratification systems of thyroid nodules in a prospective series of thyroid nodules submitted to FNAC. Patients and methods: We prospectively evaluated 432 thyroid nodules selected for FNAC from 340 patients...
April 16, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29664659/acute-suppurative-thyroiditis-with-thyroid-abscess-and-bilateral-pneumonia-a-case-report
#12
Aleksandar Karanikolic, Miodrag Djordjevic, Nebojsa Djordjevic, Ivan Pesic, Lidija Djordjevic, Aleksandar Zlatic, Toplica Bojic, Vesna Karanikolic
Acute suppurative thyroiditis (AST) leading to thyroid abscess is a rare clinical entity. The aim of this article is to demonstrate a case of severe bilateral pneumonia which originated from a thyroid abscess. The authors report the case of a 57-year-old woman with severe bilateral pneumonia of thyroid origin. The patient had a painful throat and dysphagia for 2 or 3 days. She also had a history of mild fever and hard breathing with a discreet cough 7 days prior to hospital admission. In the past few months, the patient had frequent pneumonias...
February 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29649016/thyroid-cancer-management-from-a-suspicious-nodule-to-targeted-therapy
#13
Francesco Perri, Antonio Giordano, Salvatore Pisconti, Franco Ionna, Maria G Chiofalo, Francesco Longo, Davide Leopardo, Giuseppina Della Vittoria Scarpati, Luciano Pezzullo
Thyroid nodules are very common, and their frequency is four to five times higher in women than in men. Most of them are benign, with only a very little percentage revealing a malignant neoplasm. About 50% of thyroid nodules are detected by self-palpation of neck, whereas the other 50% are diagnosed by neck ultrasonography and following fine-needle aspiration. Management of thyroid nodules is very difficult, because benign nodules are prevalent, whereas thyroid carcinoma is uncommon, representing only 1% of all malignancies...
April 11, 2018: Anti-cancer Drugs
https://www.readbyqxmd.com/read/29642647/erbb1-and-erbb2-positive-medullary-thyroid-carcinoma-a-case-report
#14
Michele Minuto, Emanuela Varaldo, Gianluca Marcocci, Amleto de Santanna, Ermanno Ciccone, Katia Cortese
Medullary thyroid carcinomas (MTCs) are rare thyroid tumors occurring in both sporadic and hereditary forms, whose pathogenesis is related to RET proto-oncogene alterations. MTCs originate from parafollicular cells, which produce calcitonin that represents the biochemical activity of MTC. Total thyroidectomy is the main treatment for MTC and often cures patients with confined diseases. In the presence of metastasis, the therapeutic approach depends on the rate of disease progression. We report a case of a 54-year-old female with a single, incidentally discovered, thyroid nodule of 1 cm, classified as suspicious MTC after a stimulation test with intravenous (iv) calcium...
April 10, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29613968/dosimetry-based-treatment-for-graves-disease
#15
Steve L Hyer, Brenda Pratt, Matthew Gray, Sarah Chittenden, Yong Du, Clive L Harmer, Glenn D Flux
OBJECTIVE: The aim of this retrospective study was to assess the long-term outcome of a personalized dosimetry approach in Graves' disease aiming to render patients euthyroid from a planned thyroid absorbed dose of 60 Gy. PATIENTS AND METHODS: A total of 284 patients with Graves' disease were followed prospectively following administration of radioiodine calculated to deliver an absorbed dose of 60 Gy. Patients with cardiac disease were excluded. Outcomes were analysed at yearly intervals for up to 10 years with a median follow-up of 37...
April 2, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29607563/investigation-of-thyroid-nodules-a-practical-algorithm-and-review-of-guidelines
#16
REVIEW
Jin Soo A Song, Adam A Dmytriw, Eugene Yu, Reza Forghani, Lorne Rotstein, David Goldstein, Colin S Poon
BACKGROUND: High resolution ultrasound has led to early detection of subclinical tumors and drastic increase in incidence of thyroid malignancy. To achieve a balance in appropriate investigation without perpetuating an overdiagnosis phenomenon, a concise set of evidence-based recommendations to stratify risk is required. METHODS: We sought to assemble an evidence-based diagnostic algorithm and accompanying pictorial review for workup of thyroid nodules that summarizes the most recent guidelines...
April 1, 2018: Head & Neck
https://www.readbyqxmd.com/read/29607233/preterm-parturient-with-polyhydramnios-and-pancreatitis-primary-presentation-of-hyperparathyroidism
#17
Esther S Han, Katherine Fritton, Phoebe Bacon, Martin K Slodzinski, Cynthia Argani
Objective: To report a case of severe hypercalcemia secondary to primary hyperparathyroidism in a late-preterm pregnant patient and review medical and surgical treatments as well as obstetric and neonatal outcomes. Background: Diagnosis of parathyroid disease during pregnancy can be difficult due to nonspecific presentation. Management decisions are complex and require multidisciplinary collaboration. Case: A 29-year-old G2P1001 woman at 35 weeks and 3 days' gestation presented with preterm contractions, polyhydramnios, pancreatitis, and severe hypercalcemia...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29605452/efficiency-of-the-bethesda-system-for-thyroid-cytopathology
#18
Ismael Mora-Guzmán, José Luis Muñoz de Nova, Cristina Marín-Campos, José Antonio Jiménez-Heffernan, Juan Julián Cuesta Pérez, Marcos Lahera Vargas, Emma Torres Mínguez, Elena Martín-Pérez
INTRODUCTION: Fine-needle aspiration biopsies are a key tool for preoperative assessment of thyroid nodules, and the Bethesda system is the preferred method to report cytological analysis. The purpose of this study is to assess the efficiency of the Bethesda system to identify the malignancy risk of thyroid nodules. METHODS: Patients who underwent thyroid surgery between June 2010 and June 2017 were included. Samples were classified into 6categories according to rates of malignancy associated with each diagnostic category...
March 28, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29594053/indeterminate-thyroid-nodules-a-pragmatic-approach
#19
Aly Bernard Khalil, Roberto Dina, Karim Meeran, Ali M Bakir, Saf Naqvi, Alia Al Tikritti, Nader Lessan, Maha T Barakat
Background: Fine needle aspiration (FNA) cytology fails to provide a conclusive diagnosis in a subset of thyroid lesions labeled as "indeterminate" (Thy3). In this study, we aimed at ascertaining the prevalence of Thy3 thyroid nodules in a hitherto unreported ethnic group (residents of the United Arab Emirates). Methods: We retrospectively examined 688 FNA of the thyroid performed on 584 patients. Samples were reported using the Royal College of Physicians' (RCP) Thy classification...
January 2018: European Thyroid Journal
https://www.readbyqxmd.com/read/29589393/a-comparison-of-ultrasound-guided-fine-needle-aspiration-versus-core-needle-biopsy-for-thyroid-nodules-pain-tolerability-and-complications
#20
Eun Ji Jeong, Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Jae Kyun Kim, Jeong Hyun Lee
BACKGROUND: To compare pain, tolerability, and complications associated with fine needle aspiration (FNA) versus core needle biopsy (CNB). METHODS: FNAs were performed using 23-gauge needles and CNBs were performed using 18-gauge double-action spring-activated needles in 100 patients for each procedure. Patients were asked to record a pain score using a 10-cm visual analog scale and procedure tolerability. Complications and number of biopsies were recorded. RESULTS: The median pain scores were similar for the FNA and CNB approaches during and 20 minutes after the biopsy procedures (3...
March 2018: Endocrinology and Metabolism
keyword
keyword
23926
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"