keyword
MENU ▼
Read by QxMD icon Read
search

Stereotactic radiosurgery

keyword
https://www.readbyqxmd.com/read/28803169/stereotactic-radiosurgery-for-dural-arteriovenous-fistulas-without-cortical-venous-reflux
#1
Daniel A Tonetti, Bradley A Gross, Brian T Jankowitz, Kyle M Atcheson, Hideyuki Kano, Edward A Monaco, Ajay Niranjan, L Dade Lunsford
BACKGROUND: The rationale for treatment of dural arteriovenous fistulas (dAVF) without cortical venous reflux is symptomatic resolution. Most studies of dural arteriovenous fistula treatment, including those for stereotactic radiosurgery (SRS), have focused on angiographic obliteration instead of clinical symptomatic outcome. METHODS: The authors evaluated their institutional experience with SRS for cerebral dAVFs without cortical venous reflux from 1991 to 2016, evaluating angiographic and clinical outcomes, focusing on the course of pulsatile tinnitus and/or ocular symptoms after treatment...
August 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28799876/melanoma-brain-metastasis-the-impact-of-stereotactic-radiosurgery-braf-mutational-status-and-targeted-and-or-immune-based-therapies-on-treatment-outcome
#2
Rupesh Kotecha, Jacob A Miller, Vyshak A Venur, Alireza M Mohammadi, Samuel T Chao, John H Suh, Gene H Barnett, Erin S Murphy, Pauline Funchain, Jennifer S Yu, Michael A Vogelbaum, Lilyana Angelov, Manmeet S Ahluwalia
OBJECTIVE The goal of this study was to investigate the impact of stereotactic radiosurgery (SRS), BRAF status, and targeted and immune-based therapies on the recurrence patterns and factors associated with overall survival (OS) among patients with melanoma brain metastasis (MBM). METHODS A total of 366 patients were treated for 1336 MBMs; a lesion-based analysis was performed on 793 SRS lesions. The BRAF status was available for 78 patients: 35 had BRAF (mut) and 43 had BRAF wild-type ( BRAF-WT) lesions. The Kaplan-Meier method evaluated unadjusted OS; cumulative incidence analysis determined the incidences of local failure (LF), distant failure, and radiation necrosis (RN), with death as a competing risk...
August 11, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28795286/diagnostic-and-therapeutic-strategies-for-patients-with-malignant-epidural-spinal-cord-compression
#3
REVIEW
Dilan A Patel, Jian L Campian
Malignant epidural spinal cord compression (MESCC) is an oncologic emergency with the potential for devastating consequences for patients if not promptly diagnosed and treated. MESCC is diagnosed by imaging. MRI is by far the most sensitive test, preferably with gadolinium. Once the diagnosis of MESCC is suspected, patients with neurologic deficits should receive prompt administration of dexamethasone with a 10-mg IV loading dose followed by 4 mg every 6 h. Quick taper is recommended once the definitive treatment is established...
August 10, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28791250/immunotherapy-combined-with-large-fractions-of-radiotherapy-stereotactic-radiosurgery-for-brain-metastases-implications-for-intraoperative-radiotherapy-after-resection
#4
REVIEW
Carsten Herskind, Frederik Wenz, Frank A Giordano
Brain metastases (BM) affect approximately a third of all cancer patients with systemic disease. Treatment options include surgery, whole-brain radiotherapy, or stereotactic radiosurgery (SRS) while chemotherapy has only limited activity. In cases where patients undergo resection before irradiation, intraoperative radiotherapy (IORT) to the tumor bed may be an alternative modality, which would eliminate the repopulation of residual tumor cells between surgery and postoperative radiotherapy. Accumulating evidence has shown that high single doses of ionizing radiation can be highly efficient in eliciting a broad spectrum of local, regional, and systemic tumor-directed immune reactions...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28776956/first-follow-up-radiographic-response-is-one-of-the-predictors-of-local-tumor-progression-and-radiation-necrosis-after-stereotactic-radiosurgery-for-brain-metastases
#5
Mayur Sharma, Xuefei Jia, Manmeet Ahluwalia, Gene H Barnett, Michael A Vogelbaum, Samuel T Chao, John H Suh, Erin S Murphy, Jennifer S Yu, Lilyana Angelov, Alireza M Mohammadi
Local progression (LP) and radiation necrosis (RN) occur in >20% of cases following stereotactic radiosurgery (SRS) for brain metastases (BM). Expected outcomes following SRS for BM include tumor control/shrinkage, local progression and radiation necrosis. 1427 patients with 4283 BM lesions were treated using SRS at Cleveland Clinic from 2000 to 2012. Clinical, imaging and radiosurgery data were collected from the database. Local tumor progression and RN were the primary end points and correlated with patient and tumor-related variables...
August 4, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28771971/do-we-need-a-new-ct-scan-for-retreatment-of-intracranial-srs-patients
#6
David Wiant, Matthew Manning, Kyle Koch, Jacqueline Maurer, Lane Hayes, Han Liu, Qingyang Shang, Benjamin Sintay
PURPOSE: To determine if the treatment planning computed tomography scan (CT) from an initial intracranial stereotactic radiosurgery (SRS) treatment can be used for repeat courses of SRS. METHODS AND MATERIALS: Twenty-five patients with 40 brain metastases that received multiple courses of SRS were retrospectively studied. Magnetic resonance scans from repeat SRS (rMR) courses were registered to CT scans from the initial SRS (iCT) and repeat SRS (rCT). The CT scans were then registered to find the displacement of the rMR between iCT and rCT registrations...
August 3, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28766885/technical-note-construction-of-heterogeneous-head-phantom-for-quality-control-in-stereotactic-radiosurgery
#7
Mohsen Najafi, Javad Teimouri, Alireza Shirazi, Ghazaleh Geraily, Mahbod Esfahani, Mostafa Shafaei
PURPOSE: Stereotactic radiosurgery is a high precision modality for conformally delivering high doses of radiation to the brain lesion with a large dose volume. Several studies for the quality control of this technique were performed to measure the dose delivered to the target with a homogenous head phantom and some dosimeters. Some studies were also performed with one or two instances of heterogeneity in the head phantom to measure the dose delivered to the target. But these studies assumed the head as a sphere and simple shape heterogeneity...
August 2, 2017: Medical Physics
https://www.readbyqxmd.com/read/28760560/hippocampal-dose-from-stereotactic-radiosurgery-for-4-to-10-brain-metastases-risk-factors-feasibility-of-dose-reduction-via-re-optimization-and-patient-outcomes
#8
Samuel R Birer, Adam C Olson, Justus Adamson, Rodney Hood, Matthew Susen, Grace Kim, Joseph K Salama, John P Kirkpatrick
This study aimed to report hippocampal dose from single-fraction stereotactic radiosurgery (SRS) for 4 to 10 brain metastases and determine feasibility of hippocampal-sparing SRS. Patients with 4 to 10 brain metastases receiving single-isocenter, multi-target single-fraction SRS were identified. Hippocampi were contoured using the Radiation Therapy Oncology Group (RTOG) 0933 atlas. RTOG 0933 dose constraints were converted to a biologically effective dose using an alpha/beta of 2 (D100 421 cGy, Dmax 665 cGy)...
July 28, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28758408/radiation-therapy-for-who-grade-i-meningioma
#9
Samuel E Day, Lia M Halasz
Maximal safe resection has long been the cornerstone of treatment for WHO grade I benign meningioma. However, as technology for both imaging and radiation delivery has advanced, radiation therapy has played an increasingly important role in the management of patients with WHO grade I meningioma. Radiation therapy, whether delivered as standard fractionated treatment over several weeks, stereotactic radiosurgery over 1 session, or multisession stereotactic radiation therapy, has been shown to provide excellent local control when used as an adjunct to surgery or as primary treatment...
July 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28757759/treating-intracranial-dural-arteriovenous-fistulas-with-gamma-knife-radiosurgery-a-single-center-experience
#10
Guan-Chyuan Wang, Kuan-Pin Chen, Tsung-Lang Chiu, Chain-Fa Su
OBJECTIVE: We evaluated the effectiveness and safety of gamma knife radiosurgery (GKRS) for the treatment of intracranial dural arteriovenous fistulas (dural AVFs) over the past 10 years. MATERIALS AND METHODS: The records of 21 patients diagnosed with dural AVFs between 2004 and 2014 and treated with GKRS were reviewed retrospectively. Complete obliteration (CO) was defined as total symptom relief plus confirmation through magnetic resonance imaging or conventional angiography...
January 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28754641/improving-the-prognostic-value-of-disease-specific-graded-prognostic-assessment-ds-gpa-model-for-renal-cell-carcinoma-by-incorporation-of-cumulative-intracranial-tumor-volume-citv
#11
Mir Amaan Ali, Brian R Hirshman, Bayard Wilson, Alexander J Schupper, Rushikesh Joshi, James A Proudfoot, Steven J Goetsch, John F Alksne, Kenneth Ott, Hitoshi Aiyama, Osamu Nagano, Bob S Carter, Veronica Chiang, Toru Serizawa, Masaaki Yamamoto, Clark C Chen
BACKGROUND: We tested the prognostic value of cumulative intracranial tumor volume (CITV) in the context of ds-GPA model for renal cell carcinoma (RCC) patients with brain metastasis (BM) treated with stereotactic radiosurgery (SRS). METHODS: Patient and tumor characteristics were collected from RCC cohorts with newly BM who underwent SRS. Univariable and multivariable logistic regression model was used to test the prognostic value of CITV, Karnofsky Performance Score (KPS), and the number of BM...
July 25, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28751141/histology-stratified-tumor-control-and-patient-survival-following-stereotactic-radiosurgery-for-pineal-region-tumors-a-report-from-the-international-gamma-knife-research-foundation
#12
Christian Iorio-Morin, Hideyuki Kano, Marshall Huang, L Dade Lunsford, Gabriela Simonová, Roman Liscak, Or Cohen-Inbar, Jason Sheehan, Cheng-Chia Lee, Hsiu-Mei Wu, David Mathieu
OBJECT: Pineal region tumors represent a rare and histologically diverse group of lesions. Few studies are available to guide management and the outcomes following stereotactic radiosurgery (SRS) are unknown for many histologies. METHODS: Patients who underwent SRS for a pineal region tumor and for whom at least 6 months of imaging follow-up was available were retrospectively assessed in five centers. Data was collected from the medical record and histology-level analyses were performed, including actuarial tumor control and survival analyses...
July 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28746939/consistency-between-targets-delineated-by-angiography-computed-tomography-and-magnetic-resonance-imaging-in-stereotactic-radiosurgery-for-arteriovenous-malformation
#13
Yu-Jie Huang, Shih-Wei Hsu, Tsair-Fwu Lee, Jih-Tsun Ho, Wu-Fu Chen
BACKGROUND: Target identification is important for radiosurgery for arteriovenous malformations (AVMs). Targets defined by different imaging modalities may be inconsistent in practice. OBJECTIVES: The goal of this study is to review and analyze the consistency between targets defined by different imaging modalities in radiosurgery for AVMs. METHODS: From March 2007 to June 2011, AVM patients for radiosurgery whose targets were delineated by angiography/computed tomography (CT)/magnetic resonance imaging (MRI) were reviewed...
July 27, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28743240/whole-brain-radiotherapy-versus-stereotactic-radiosurgery-for-4-10-brain-metastases-a-phase-iii-randomised-multicentre-trial
#14
Jaap D Zindler, Anna M E Bruynzeel, Daniëlle B P Eekers, Coen W Hurkmans, Ans Swinnen, Philippe Lambin
BACKGROUND: Maintenance of quality of life is the primary goal during treatment of brain metastases (BM). This is a protocol of an ongoing phase III randomised multicentre study. This study aims to determine the exact additional palliative value of stereotactic radiosurgery (SRS) over whole brain radiotherapy (WBRT) in patients with 4-10 BM. METHODS: The study will include patients with 4-10 BM from solid primary tumours diagnosed on a high-resolution contrast-enhanced MRI scan with a maximum lesional diameter of 2...
July 25, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28743133/lymphocytic-hypophysitis-successfully-treated-with-stereotactic-radiosurgery-case-report-and-review-of-the-literature
#15
Sandra Pekic, Vojislav Bogosavljevic, Selcuk Peker, Mirjana Doknic, Dragana Miljic, Marko Stojanovic, Milica Skender-Gazibara, Emilija Manojlovic Gacic, Vera Popovic, Milan Petakov
No abstract text is available yet for this article.
July 25, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28740900/management-approach-for-recurrent-brain-metastases-following-upfront-radiosurgery-may-affect-risk-of-subsequent-radiation-necrosis
#16
Ali Rae, Daniel Gorovets, Paul Rava, Daniel Ebner, Deus Cielo, Timothy J Kinsella, Thomas A DiPetrillo, Jaroslaw T Hepel
PURPOSE: Many patients treated with stereotactic radiosurgery (SRS) alone as initial treatment require 1 or more subsequent salvage therapies. This study aimed to determine if commonly used salvage strategies are associated with differing risks of radiation necrosis (RN). METHODS AND MATERIALS: All patients treated with upfront SRS alone for brain metastases at our institution were retrospectively analyzed. Salvage treatment details were obtained for brain failures...
October 2016: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28740448/evaluation-of-brain-edema-formation-defined-by-mri-after-linac-based-stereotactic-radiosurgery
#17
Maciej Harat, Andrzej Lebioda, Judyta Lasota, Roman Makarewicz
BACKGROUND: Peri-lesional edema is a serious and well-known complication of stereotactic radiosurgery (SRS). Here we evaluated edema risk after SRS and assessed its formation and resolution dynamics. PATIENTS AND METHODS: 107 patients underwent SRS for heterogeneous diagnoses: 34 (29%) with arteriovenous malformations, 38 (35%) with meningiomas, 16 (15%) with metastatic tumors, 16 (15%) with acoustic neuromas, 3 with (3%) cavernomas, and 2 (2%) each with anaplastic astrocytomas and anaplastic oligoastrocytomas...
June 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/28739316/validation-of-the-disease-specific-gpa-for-patients-with-1-to-3-synchronous-brain-metastases-in-newly-diagnosed-nsclc
#18
Neil M Woody, Matthew D Greer, Chandana A Reddy, Gregory M M Videtic, Samuel T Chao, Erin S Murphy, John H Suh, Liliana Angelov, Gene H Barnett, Michael A Vogelbaum, Kevin L Stephans
BACKGROUND: The disease-specific graded prognostic assessment (DS-GPA) for brain metastases is a powerful prognostic tool but has not been validated for patients with synchronous brain metastases (SBM) in newly diagnosed non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: We identified patients with newly diagnosed NSCLC with 1 to 3 SBM treated with stereotactic radiosurgery (SRS) between 1997 and 2012. We included patients whose brain metastases were treated with SRS alone or combined SRS and whole-brain radiotherapy (WBRT)...
July 6, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28739211/investigating-the-surface-dose-contribution-of-intrafractional-kv-imaging-in-cyberknife-based-stereotactic-radiosurgery
#19
Abdulmecit Canbolat, Faruk Zorlu, Pervin Hurmuz, Mete Yeginer, Gokhan Ozyigit
CyberKnife treatment consists of hundreds of noncoplanar beams and numerous intrafractional images that can be taken during a single treatment fraction; thus, doses because of imaging should be considered in this technique. The aim of this study is to investigate the in-field and out-of-field surface doses induced from kV imaging system during stereotactic radiosurgery (SRS) treatment. The imaging-induced surface doses were measured at the center of the imaging field and within ±15-cm distance from the center in both craniocaudal and lateral directions...
July 21, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28737065/postoperative-stereotactic-radiosurgery-for-limited-brain-metastases-are-we-ready-for-prime-time
#20
Simon S Lo, Paul D Brown, Matthew Foote, Samuel T Chao, Eric L Chang, Arjun Sahgal
No abstract text is available yet for this article.
July 24, 2017: Expert Review of Anticancer Therapy
keyword
keyword
23918
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"