keyword
MENU ▼
Read by QxMD icon Read
search

hormone transition

keyword
https://www.readbyqxmd.com/read/28634407/analysis-of-survival-and-hatching-transcriptomes-from-potato-cyst-nematodes-globodera-rostochiensis-and-g-pallida
#1
Marc-Olivier Duceppe, Joël Lafond-Lapalme, Juan Emilio Palomares-Rius, Michaël Sabeh, Vivian Blok, Peter Moffett, Benjamin Mimee
Potato cyst nematodes (PCNs), Globodera rostochiensis and G. pallida, cause important economic losses. They are hard to manage because of their ability to remain dormant in soil for many years. Although general knowledge about these plant parasitic nematodes has considerably increased over the past decades, very little is known about molecular events involved in cyst dormancy and hatching, two key steps of their development. Here, we have studied the progression of PCN transcriptomes from dry cysts to hatched juveniles using RNA-Seq...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28625150/update-on-the-molecular-mechanisms-underlying-the-effect-of-cholecystokinin-and-cholecystokinin-1-receptor-on-the-formation-of-cholesterol-gallstones
#2
Helen H Wang, Piero Portincasa, David Q-H Wang
Cholecystokinin (CCK) is an important neuro-intestinal peptide hormone produced by the enteroendocrine I-cells in the upper part of small intestine. Protein- and fat-enriched food plays an important role in triggering CCK secretion from the intestine. Carbohydrates stimulate only small amounts of CCK release. The CCK-1 receptor (CCK-1R) is largely localized in the gallbladder, sphincter of Oddi, pancreas, small intestine, gastric mucosa, and pyloric sphincter, where it is responsible for CCK to regulate multiple digestive processes including gallbladder contraction, pancreatic secretion, small intestinal transit, and gastric emptying...
June 19, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28624683/drought-responsive-micrornas-in-two-barley-cultivars-differing-in-their-level-of-sensitivity-to-drought-stress
#3
Ehsan Mohseni Fard, Behnam Bakhshi, Reza Keshavarznia, Nava Nikpay, Maryam Shahbazi, Ghasem Hosseini Salekdeh
MicroRNAs (miRNAs) are known to be involved in the regulation of gene expression, including that of genes involved in the response to stress. Here, a comparison has been drawn between the miRNA profiles of a drought susceptible, 'Morocco 9-75', and a drought tolerant, 'Yousef', barley cultivars. Leaf water content, shoot dry matter and chlorophyll content decreased in 'Morocco 9-75' more considerably compared with 'Yousef' under drought stress. Furthermore, lower stomatal conductance and higher leaf temperature were observed in 'Morocco 9-75' compared with 'Yousef'...
June 7, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28615628/glucocorticoids-ameliorate-tgf-%C3%AE-1-mediated-epithelial-to-mesenchymal-transition-of-airway-epithelium-through-mapk-and-snail-slug-signaling-pathways
#4
Hyun-Woo Yang, Seoung-Ae Lee, Jae-Min Shin, Il-Ho Park, Heung-Man Lee
Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP. Glucocorticoids are a type of steroid hormone that is used primarily in medical therapy for patients with CRSwNP; however, their effects on EMT in the airway epithelium remain unknown. To investigate the effects of dexamethasone and fluticasone propionate, a class of glucocorticoids, on transforming growth factor-β1 (TGF-β1) -induced EMT, we used A549 cells, human primary nasal epithelial cells (hPNECs) and ex vivo organ culture of the inferior turbinate...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28612586/sociological-transition-and-breast-cancer-in-the-arab-world-the-experience-of-lebanon
#5
Najla A Lakkis, Salim M Adib, Ghassan Hamadeh, Rana El Jarrah, Mona H Osman
Background: Breast cancer is the leading cause of cancer death among females in Lebanon. This study aimed at analyzing its epidemiology in the country over time. Methods: Data were extracted from the Lebanese National Cancer Registry (NCR) for the years 2004 through 2010. Age-standardized and age-specific incidence rates for cancers per 100,000 population were calculated. Results: Breast cancer ranked first, accounting for an average of 37.6% of all new female cancer cases in Lebanon during the period of 2004-2010...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28601458/ad-libitum-milk-replacer-feeding-but-not-butyrate-supplementation-affects-growth-performance-as-well-as-metabolic-and-endocrine-traits-in-holstein-calves
#6
D Frieten, C Gerbert, C Koch, G Dusel, K Eder, E Kanitz, J M Weitzel, H M Hammon
The enhanced growth performance of calves fed a higher plane of nutrition pre-weaning is well documented, and the effect of butyrate on the development of the gastrointestinal tract in calves has been evaluated. The aim of this study was to examine the synergistic effects of ad libitum milk replacer (MR) feeding and butyrate supplementation on growth performance and energy metabolism in calves. Sixty-four (32 male, 32 female) Holstein calves were examined from birth until wk 11 of life. Calves received MR either ad libitum (Adl) or restrictively (Res) with (AdlB+, ResB+) or without (AdlB-, ResB-) 0...
June 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28600354/synergistic-action-of-auxin-and-cytokinin-mediates-aluminum-induced-root-growth-inhibition-in-arabidopsis
#7
Zhong-Bao Yang, Guangchao Liu, Jiajia Liu, Bing Zhang, Wenjing Meng, Bruno Müller, Ken-Ichiro Hayashi, Xiansheng Zhang, Zhong Zhao, Ive De Smet, Zhaojun Ding
Auxin acts synergistically with cytokinin to control the shoot stem-cell niche, while both hormones act antagonistically to maintain the root meristem. In aluminum (Al) stress-induced root growth inhibition, auxin plays an important role. However, the role of cytokinin in this process is not well understood. In this study, we show that cytokinin enhances root growth inhibition under stress by mediating Al-induced auxin signaling. Al stress triggers a local cytokinin response in the root-apex transition zone (TZ) that depends on IPTs, which encode adenosine phosphate isopentenyltransferases and regulate cytokinin biosynthesis...
June 9, 2017: EMBO Reports
https://www.readbyqxmd.com/read/28588281/a-central-small-amino-acid-in-the-vamp2-transmembrane-domain-regulates-the-fusion-pore-in-exocytosis
#8
Benoît Hastoy, Pier A Scotti, Alexandra Milochau, Zahia Fezoua-Boubegtiten, Jorge Rodas, Rémi Megret, Bernard Desbat, Michel Laguerre, Sabine Castano, David Perrais, Patrik Rorsman, Reiko Oda, Jochen Lang
Exocytosis depends on cytosolic domains of SNARE proteins but the function of the transmembrane domains (TMDs) in membrane fusion remains controversial. The TMD of the SNARE protein synaptobrevin2/VAMP2 contains two highly conserved small amino acids, G100 and C103, in its central portion. Substituting G100 and/or C103 with the β-branched amino acid valine impairs the structural flexibility of the TMD in terms of α-helix/β-sheet transitions in model membranes (measured by infrared reflection-absorption or evanescent wave spectroscopy) during increase in protein/lipid ratios, a parameter expected to be altered by recruitment of SNAREs at fusion sites...
June 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28586020/altered-expression-of-epithelial-mesenchymal-transition-and-pluripotent-associated-markers-by-sex-steroid-hormones-in-human-embryonic-stem-cells
#9
So-Ye Jeon, Kyung-A Hwang, Cho-Won Kim, Eui-Bae Jeung, Kyung-Chul Choi
Embryonic stem (ES) cells are pluripotent stem cells derived from a developmental stage of pre‑implanted embryos. The present study investigated the effect of female sex steroid hormones on the characteristics of human ES cells by using a feeder‑free culture protocol. In a feeder‑free condition without sex hormones, human ES cells assumed the form of tightly packed cells that grow in a monolayer. The cells had clean and defined edges with no evidence of differentiation and expressed several markers specific for undifferentiated ES cells including POU class 5 homeobox 1 (POU5F1), sex determining region Y‑box 2 (SOX2) and NANOG homeobox (NANOG)...
July 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28585198/fat-cell-and-fatty-acid-turnover-in-obesity
#10
Atilla Engin
The ratio of free fatty acid (FFA) turnover decreases significantly with the expansion of white adipose tissue. Adipose tissue and dietary saturated fatty acid levels significantly correlate with an increase in fat cell size and number. Inhibition of adipose triglyceride lipase leads to an accumulation of triglyceride, whereas inhibition of hormone-sensitive lipase leads to the accumulation of diacylglycerol. The G0/G1 switch gene 2 increases lipid content in adipocytes and promotes adipocyte hypertrophy through the restriction of triglyceride turnover...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28584126/temperature-variability-is-integrated-by-a-spatially-embedded-decision-making-center-to-break-dormancy-in-arabidopsis-seeds
#11
Alexander T Topham, Rachel E Taylor, Dawei Yan, Eiji Nambara, Iain G Johnston, George W Bassel
Plants perceive and integrate information from the environment to time critical transitions in their life cycle. Some mechanisms underlying this quantitative signal processing have been described, whereas others await discovery. Seeds have evolved a mechanism to integrate environmental information by regulating the abundance of the antagonistically acting hormones abscisic acid (ABA) and gibberellin (GA). Here, we show that hormone metabolic interactions and their feedbacks are sufficient to create a bistable developmental fate switch in Arabidopsis seeds...
June 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28583600/administration-of-2-5%C3%A2-mg-of-estradiol-followed-by-1-500%C3%A2-mg-of-progesterone-to-anovulatory-mares-promote-similar-uterine-morphology-hormone-concentrations-and-molecular-dynamics-to-those-observed-in-cyclic-mares
#12
E S M Silva, F S Ignácio, S C Fritsch, D S Zanoni, J C F Pantoja, J P Oliveira-Filho, C Meira
To test the hypothesis that the administration of 2.5 mg of estradiol benzoate (EB) followed by 1500 mg of long acting progesterone (LA P4) causes similar uterine changes and molecular dynamics in anovulatory mares to those observed in cyclic ones, we evaluated the changes of estrogen (ERα and ERβ) and progesterone receptors (PR) in anestrous, transitional and cyclic mares by RT-qPCR and immunohistochemistry. In addition, we evaluated uterine edema, tonus and estrogens and progesterone plasma profile. Endometrial biopsies were taken from anestrous and transitional mares immediately before EB injection, 48 h after EB administration and five days after LA P4 was given...
July 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28578932/ovarian-hormones-organize-the-maturation-of-inhibitory-neurotransmission-in-the-frontal-cortex-at-puberty-onset-in-female-mice
#13
David J Piekarski, Josiah R Boivin, Linda Wilbrecht
The frontal cortex matures late in development, showing dramatic changes after puberty onset, yet few experiments have directly tested the role of pubertal hormones in cortical maturation. One mechanism thought to play a primary role in regulating the maturation of the neocortex is an increase in inhibitory neurotransmission, which alters the balance of excitation and inhibition. We hypothesized that pubertal hormones could regulate maturation of the frontal cortex by this mechanism. Here, we report that manipulations of gonadal hormones do significantly alter the maturation of inhibitory neurotransmission in the cingulate region of the mouse medial frontal cortex, an associative region that matures during the pubertal transition and is implicated in decision making, learning, and psychopathology...
June 19, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28576864/lin-41-and-oma-ribonucleoprotein-complexes-mediate-a-translational-repression-to-activation-switch-controlling-oocyte-meiotic-maturation-and-the-oocyte-to-embryo-transition-in-caenorhabditis-elegans
#14
Tatsuya Tsukamoto, Micah D Gearhart, Caroline A Spike, Gabriela Huelgas-Morales, Makaela Mews, Peter R Boag, Traude H Beilharz, David Greenstein
An extended meiotic prophase is a hallmark of oogenesis. Hormonal signaling activates the CDK1/cyclin B kinase to promote oocyte meiotic maturation, which involves nuclear and cytoplasmic events. Nuclear maturation encompasses nuclear envelope breakdown, meiotic spindle assembly, and chromosome segregation. Cytoplasmic maturation involves major changes in oocyte protein translation and cytoplasmic organelles and is poorly understood. In the nematode Caenorhabditis elegans, sperm release the major sperm protein (MSP) hormone to promote oocyte growth and meiotic maturation...
June 1, 2017: Genetics
https://www.readbyqxmd.com/read/28576647/testosterone-oxytocin-and-the-development-of-human-parental-care
#15
Ilanit Gordon, Maayan Pratt, Katharina Bergunde, Orna Zagoory-Sharon, Ruth Feldman
The steroid testosterone (T) and neuropeptide oxytocin (OT) have each been implicated in the development of parental care in humans and animals, yet very little research addressed the interaction between these hormones at the transition to parenthood in mothers and fathers. One hundred and sixty mothers and fathers (80 couples) were visited 1 and 6months after the birth of their first child, plasma OT and T were assayed at each time-point, and interactions between each parent and the infant were observed and micro-coded for two key parental behaviors; affectionate touch and parent-infant synchrony...
May 30, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/28570685/comparative-transcription-analysis-of-different-antirrhinum-phyllotaxy-nodes-identifies-major-signal-networks-involved-in-vegetative-reproductive-transition
#16
Dongliang Wang, Geyang Cao, Peng Fang, Lin Xia, Beijiu Cheng
Vegetative-reproductive phase change is an indispensable event which guarantees several aspects of successful meristem behaviour and organ development. Antirrhinum majus undergoes drastic changes of shoot architecture during the phase change, including phyllotactic change and leaf type alteration from opposite decussate to spiral. However, the regulation mechanism in both of phyllotactic morphology changes is still unclear. Here, the Solexa/Illumina RNA-seq high-throughput sequencing was used to evaluate the global changes of transcriptome levels among four node regions during phyllotactic development...
2017: PloS One
https://www.readbyqxmd.com/read/28546125/molecular-cloning-and-functional-characterization-of-coft1-a-homolog-of-flowering-locus-t-ft-from-camellia-oleifera
#17
Hengjiu Lei, Shuchai Su, Luyi Ma, Yue Wen, Xiangnan Wang
FLOWERING LOCUS T (FT) is an important integrator of flowering genetic pathways and plays crucial roles in flowering transition. The tea-oil tree (Camellia oleifera Abel.) is a valuable woody oil crop, but the molecular mechanisms controlling flowering are still unclear. In this study, a FT-like gene, CoFT1, was isolated and characterized from C. oleifera. The CoFT1 protein was localized in the nucleus and cytoplasm of Arabidopsis protoplasts, and exhibited no transactivation activity in yeast cells. CoFT1 was highly expressed in mature leaves and reproductive organs, such as flower buds, flowers, flower organs, and young fruits...
May 22, 2017: Gene
https://www.readbyqxmd.com/read/28545056/effect-of-helicobacter-pylori-infection-on-the-link-between-glp-1-expression-and-motility-of-the-gastrointestinal-tract
#18
Hirotsugu Eda, Hirokazu Fukui, Ryosuke Uchiyama, Yoshitaka Kitayama, Ken Hara, Mo Yang, Mio Kodani, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari, Hiroko Tsutsui, Hiroto Miwa
BACKGROUND: Although Helicobacter pylori (H. pylori) infection is closely associated with the development of peptic ulcer, its involvement in pathophysiology in the lower intestinal tract and gastrointestinal (GI) motility remains unclear. Glucagon-like peptide-1 (GLP-1) is a gut hormone produced in the lower intestinal tract and involved in GI motility. Here, we investigated the effect of H. pylori infection on the link between GLP-1 expression and motility of the GI tract. METHODS: C57BL/6 mice were inoculated with a H...
2017: PloS One
https://www.readbyqxmd.com/read/28545028/stc1-promotes-cell-apoptosis-via-nf-%C3%AE%C2%BAb-phospho-p65-ser536-in-cervical-cancer-cells
#19
Xi Pan, Binyuan Jiang, Jianhao Liu, Juan Ding, Yuehui Li, Ruili Sun, Li Peng, Changfei Qin, Shujuan Fang, Guancheng Li
Stanniocalin-1 (STC1) is a secreted glycoprotein hormone and involved in various types of human malignancies. Our previous studies revealed that STC1 inhibited cell proliferation and invasion of cervical cancer cells through NF-κB P65 activation, but the mechanism is poorly understood. In our studies, we found overexpression of STC1 promoted cell apoptosis while silencing of STC1 promoted cell growth of cervical cancer. Phospho-protein profiling and Western blotting results showed the expression of NF-κB related phosphorylation sites including NF-κB P65 (Ser536), IκBα, IKKβ, PI3K, and AKT was altered in STC1-overexpressed cervical cancer cells...
May 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28539237/effects-of-sex-steroids-on-the-pattern-of-methylation-and-expression-of-the-promoter-region-of-estrogen-and-androgen-receptors-in-people-with-gender-dysphoria-under-cross-sex-hormone-treatment
#20
Gloria Aranda, Eduardo Fernández-Rebollo, Marta Pradas-Juni, Felicia Alexandra Hanzu, Susana G Kalko, Irene Halperin, Mireia Mora
Cross-sex hormone therapy (CHT) is critical for phenotypical and physiological transition in adults with gender dysphoria (GD). However, the impact of the CHT onto the molecular level/epigenetic regulation has not been comprehensively addressed. We postulate that CHT in GD could drive changes at the androgen receptor (AR), estrogen receptor alpha (ESR1) and estrogen receptor beta (ESR2), affecting their DNA methylation pattern and mRNA expression that may influence in the phenotypical changes associated to CHT...
May 21, 2017: Journal of Steroid Biochemistry and Molecular Biology
keyword
keyword
2391
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"