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Bipolar mood disorder

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https://www.readbyqxmd.com/read/28340448/structural-correlates-of-creative-thinking-in-patients-with-bipolar-disorder-and-healthy-controls-a-voxel-based-morphometry-study
#1
Pei-Chi Tu, Yi-Hsuan Kuan, Cheng-Ta Li, Tung-Ping Su
BACKGROUND: This study investigated the structural correlates of creative thinking in patients with bipolar disorder (BD) to understand the possible neural mechanism of creative thinking in BD. METHODS: We recruited 59 patients with BD I or BD II (35.3±8.5 y) and 56 age- and sex-matched controls (HCs; 34±7.4 y). Each participant underwent structural magnetic resonance imaging and evaluation of creative thinking, which was assessed using two validated tools: the Chinese version of the Abbreviated Torrance Test for Adults for divergent thinking and the Chinese Word Remote Associates Test for remote association...
March 12, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28340442/neurocognitive-performance-as-an-endophenotype-for-mood-disorder-subgroups
#2
Alison K Merikangas, Lihong Cui, Monica E Calkins, Tyler M Moore, Ruben C Gur, Raquel E Gur, Kathleen R Merikangas
BACKGROUND: There is growing evidence that neurocognitive function may be an endophenotype for mood disorders. The goal of this study is to examine the specificity and familiality of neurocognitive functioning across the full range of mood disorder subgroups, including Bipolar I (BP-I), Bipolar II (BP-II), Major Depressive Disorders (MDD), and controls in a community-based family study. METHODS: A total of 310 participants from 137 families with mood spectrum disorders (n=151) and controls (n=159) completed the University of Pennsylvania's Computerized Neurocognitive Battery (CNB) that assessed the accuracy and speed of task performance across five domains...
March 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28338546/a-double-blind-placebo-controlled-pilot-study-of-riluzole-monotherapy-for-acute-bipolar-depression
#3
Lawrence T Park, Marc S Lener, Matthew Hopkins, Nicolas Iadorola, Rodrigo Machado-Vieira, Elizabeth Ballard, Allison Nugent, Carlos A Zarate
BACKGROUND: Glutamatergic system abnormalities are implicated in the pathophysiology and treatment of both major depressive disorder and bipolar depression (BDep). Subsequent to studies demonstrating the rapid and robust antidepressant effects of ketamine, an N-methyl-D-aspartate receptor antagonist, other glutamatergic modulators are now being studied in clinical trials of mood disorders. A previous open-label study found that riluzole, administered in combination with the mood stabilizer lithium, had antidepressant effects...
March 23, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28337552/clinical-utility-of-resting-state-functional-connectivity-magnetic-resonance-imaging-for-mood-and-cognitive-disorders
#4
REVIEW
T Takamura, T Hanakawa
Although functional magnetic resonance imaging (fMRI) has long been used to assess task-related brain activity in neuropsychiatric disorders, it has not yet become a widely available clinical tool. Resting-state fMRI (rs-fMRI) has been the subject of recent attention in the fields of basic and clinical neuroimaging research. This method enables investigation of the functional organization of the brain and alterations of resting-state networks (RSNs) in patients with neuropsychiatric disorders. Rs-fMRI does not require participants to perform a demanding task, in contrast to task fMRI, which often requires participants to follow complex instructions...
March 23, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28332123/self-poisoning-suicide-deaths-in-people-with-bipolar-disorder-characterizing-a-subgroup-and-identifying-treatment-patterns
#5
Ayal Schaffer, Lauren M Weinstock, Mark Sinyor, Catherine Reis, Benjamin I Goldstein, Lakshmi N Yatham, Anthony J Levitt
OBJECTIVE: To characterize self-poisoning suicide deaths in BD compared to other suicide decedents. METHODS: Extracted coroner data from all suicide deaths (n = 3319) in Toronto, Canada from 1998 to 2012. Analyses of demographics, clinical history, recent stressors, and suicide details were conducted in 5 subgroups of suicide decedents: BD self-poisoning, BD other methods, non-BD self-poisoning, non-BD other methods, and unipolar depression self-poisoning. Toxicology results for lethal and present substances were also compared between BD and non-BD self-poisoning subgroups as well as between BD and unipolar depression self-poisoning subgroups...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28331326/lithium-in-late-life-mania-a-systematic-review
#6
REVIEW
Pasquale De Fazio, Raffaele Gaetano, Mariarita Caroleo, Maria Pavia, Giovanbattista De Sarro, Andrea Fagiolini, Cristina Segura-Garcia
The prevalence of mania among >65-year-olds ranges from 0.1% to 0.4% and its treatment is a particular challenge for clinicians. Although lithium is the treatment of choice for bipolar disorder (BD), its use in elderly population was recently questioned. This study provides a comprehensive review of literature on the efficacy and tolerability of lithium as a pharmacologic treatment for mania in elderly BD patients. We conducted a systematic review, based on PRISMA guidelines, of articles published between 1970 and August 2016 and indexed in the following databases: EMBASE, MEDLINE, Cochrane Library Databases and PsycINFO...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28331323/bipolar-disorder-recurrence-prevention-using-self-monitoring-daily-mood-charts-case-reports-from-a-5-year-period
#7
Norio Yasui-Furukori, Kazuhiko Nakamura
Mood symptoms in bipolar disorders are significantly related to psychosocial events, and the personalized identification of symptom triggers is important. Ecological momentary assessments have been used in paper-and-pencil form to explore emotional reactivity to daily life stress in patients with bipolar disorder. However, there are few data on long-term recurrence prevention effects using ecological momentary assessments. Subjects were three outpatients with bipolar disorder who had a history of at least one admission...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28328011/when-emotional-pain-becomes-physical-adverse-childhood-experiences-pain-and-the-role-of-mood-and-anxiety-disorders
#8
Natalie J Sachs-Ericsson, Julia L Sheffler, Ian H Stanley, Jennifer R Piazza, Kristopher J Preacher
OBJECTIVE: We examined the association between retrospective reports of adverse childhood experiences (ACEs) and painful medical conditions. We also examined the mediating and moderating roles of mood and anxiety disorders in the ACEs-painful medical conditions relationship. METHOD: Ten-year longitudinal data were obtained from the National Comorbidity Surveys (NCS-1, NCS-2; N = 5001). The NCS-1 obtained reports of ACEs, current health conditions, current pain severity, and mood and anxiety disorders...
March 22, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28326110/relationship-between-childhood-maltreatment-suicidality-and-bipolarity-a-retrospective-study
#9
Young-Min Park
OBJECTIVE: The aims of current study were to determine whether childhood maltreatment contributes to the occurrence of major depressive disorder (MDD) with bipolarity or suicidality. METHODS: In total, 132 outpatients diagnosed with MDD between 2014 and 2015 on the medical records were included. The subjects were divided into two groups according to the presence of childhood maltreatment (CM group) and no childhood maltreatment (NCM group). Depression severity and bipolarity were identified using Beck Depression Inventory (BDI) and the Korean version of Mood Disorder Questionnaire (K-MDQ) respectively on the medical records...
March 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28318493/-bipolar-disorders-in-oncology-characteristics-and-management
#10
Michel Reich, Nuria Kotecki
Bipolar disorders belong to the spectrum of mood disorders and represent a serious psychiatric comorbidity. Behaviors adopted by bipolar patients can foster cancer occurrence but also impact its management, especially during acute depressive or manic episode. Oncologists must adapt their protocols in order to obtain the best compliance for treatment and avoid any possible mood destabilization, with the inherent risk of suicidal attempt. Potential interactions between mood-stabilizing agents (lithium, divalproate, atypical antipsychotics, and anticonvulsivants) and oncologic treatment (chemotherapy, targeted therapy, immunotherapy, corticotherapy) will be particularly watched...
March 15, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28300934/an-evolutionary-approach-to-mania-studying-sardinian-immigrants-to-argentina
#11
Mauro G Carta, Alessandra Perra, Michela Atzeni, Silvia D'Oca, Maria F Moro, Peter K Kurotschka, Daniela Moro, Federica Sancassiani, Luigi Minerba, Maria V Brasesco, Gustavo Mausel, Antonio E Nardi, Leonardo Tondo
Objective: To ascertain lifetime prevalence of positivity to a screening questionnaire for bipolar disorders (BD) in Sardinian immigrants to Argentina and residents of Sardinia and assess whether such positivity affects quality of life (QoL) in either group. Our hypothesis is that screen positivity for BD may be more frequent in immigrants. Methods: Observational study. Subjects were randomly selected from the membership lists of associations of Sardinian immigrants in Argentina...
March 9, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28291043/repetitive-transcranial-magnetic-stimulation-and-treatment-emergent-mania-and-hypomania-a-review-of-the-literature
#12
Fady Rachid
BACKGROUND: This review focuses on treatment-emergent mania/hypomania (TEM) associated with repetitive transcranial magnetic stimulation (rTMS). METHODS: English-language studies involving possible rTMS-induced mania/hypomania published between 1966 and 2015 were retrieved through a Medline search using the search terms mania, hypomania, mixed affective state, treatment-emergent, repetitive transcranial magnetic stimulation, and rTMS. Fifteen case series and controlled studies describing TEM associated with rTMS treatment have been published involving 24 individuals, most of whom were diagnosed with either bipolar I or II disorder or major depressive disorder...
March 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28288308/the-link-between-hypomania-risk-and-creativity-the-role-of-heightened-behavioral-activation-system-bas-sensitivity
#13
Bin-Na Kim, Seok-Man Kwon
BACKGROUND: The relationship between bipolar disorder (BD) and creativity is well-known; however, relatively little is known about its potential mechanism. We investigated whether heightened behavioral activation system (BAS) sensitivity may mediate such relationship. METHODS: Korean young adults (N=543) completed self-report questionnaires that included the Hypomanic Personality Scale (HPS), the Behavioral Activation System(BAS) Scale, the Everyday Creativity Scale (ECS), the Positive Affect and Negative Affect Schedule (PANAS), and the Altman Self-Rating Mania Scale (ASRM)...
March 2, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28287195/-pilot-study-on-nutritional-and-eating-disorders-in-children-and-mood-disorders-comorbidity-or-prodromal-traits
#14
Paola Cimbolli, Álvaro Quiñones, Carla Ugarte, Adele De Pascale
INTRODUCTION: Both children affected by nutritional and eating disorders (ED) and adults with bipolar disorder (BD) display symptoms of deficient emotional self-regulation, which can present in different forms. If we observe the clinical and developmental histories of individuals affected by EDs and BD, based on a cognitive systemic post-rationalist approach, we can hypothesise a continuum between the two disorders. The aim of this pilot study is to support the hypothesis - from an explanatory rather than a non-descriptive approach - that EDs and BD are the possible result of issues tied to biological and psychological self-regulation...
January 2017: Rivista di Psichiatria
https://www.readbyqxmd.com/read/28285254/the-predictive-role-of-daily-cognitive-stimulation-on-executive-functions-in-bipolar-disorder
#15
Charles Cotrena, Laura Damiani Branco, André Ponsoni, Flávio Milman Shansis, Renata Kochhann, Rochele Paz Fonseca
This study aimed to estimate the predictive role of clinical and demographic variables on the three core executive functions (EF) - working memory (WM), inhibitory control (IC) and cognitive flexibility (CF) - in bipolar disorder (BD). The sample consisted of 38 patients with BD type I, 39 with BD type II, and 106 control participants with no mood disorders. Subjects completed the Hayling Test, Trail Making Test, Digit Span Backwards, Sentence Word Span Test, and Stroop Color-Word Test. Composite scores for WM, IC and CF were calculated, and their correlations with clinical and demographic variables were analyzed...
March 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28283835/a-developmental-approach-to-dimensional-expression-of-psychopathology-in-child-and-adolescent-offspring-of-parents-with-bipolar-disorder
#16
María Goretti Morón-Nozaleda, Covadonga M Díaz-Caneja, Elisa Rodríguez-Toscano, Celso Arango, Josefina Castro-Fornieles, Elena de la Serna, Ana Espliego, Vanessa Sanchez-Gistau, Soledad Romero, Immaculada Baeza, Gisela Sugranyes, Carmen Moreno, Dolores Moreno
The aim of this is to describe psychopathology, functioning and symptom dimensions accounting for subthreshold manifestations and developmental status in child and adolescent offspring of parents with bipolar disorder ("high-risk offspring"). The study population comprised 90 high-risk offspring (HR-offspring) and 107 offspring of community control parents (CC-offspring). Direct clinical observations and parental and offspring reports based on selected standardized clinical scales were used to assess offspring threshold and subthreshold diagnoses, symptoms and functioning...
March 10, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28280345/screening-for-bipolar-disorder-among-migraineurs-the-impact-of-migraine-bipolar-disorder-comorbidity-on-disease-characteristics
#17
Yigit Kivilcim, Merih Altintas, Fusun Mayda Domac, Erkal Erzincan, Huseyin Gülec
PURPOSE: The aim of this study was to evaluate the prevalence of comorbid bipolar disorder (BD) among migraineurs and the impact of migraine-BD comorbidity on disease characteristics. PATIENTS AND METHODS: A total of 120 adult patients diagnosed with migraine at a single tertiary care center were included in this cross-sectional study. Data on sociodemographic and migraine-related characteristics, family history of psychiatric diseases, comorbid psychiatric diseases, and first-episode characteristics were recorded...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28278600/parenting-stress-among-caregivers-of-children-with-bipolar-spectrum-disorders
#18
Guillermo Perez Algorta, Heather A MacPherson, Eric A Youngstrom, Caroline C Belt, L Eugene Arnold, Thomas W Frazier, H Gerry Taylor, Boris Birmaher, Sarah McCue Horwitz, Robert L Findling, Mary A Fristad
Caregivers of psychiatrically impaired children experience considerable parenting stress. However, no research has evaluated parenting stress within the context of pediatric bipolar spectrum disorders (BPSD). Thus, the aim of this investigation was to identify predictors and moderators of stress among caregivers in the Longitudinal Assessment of Manic Symptoms study. Participants included 640 children and their caregivers in the Longitudinal Assessment of Manic Symptoms cohort. Children had a mean age of 9...
February 26, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28278268/highs-and-lows-ups-and-downs-meteorology-and-mood-in-bipolar-disorder
#19
Ben Bullock, Greg Murray, Denny Meyer
Seasonal variation of manic and depressive symptoms is a controversial topic in bipolar disorder research. Several studies report seasonal patterns of hospital admissions for depression and mania and variation in symptoms that appear to follow a seasonal pattern, whereas others fail to report such patterns. Differences in research methodologies, data analysis strategies, and temporal resolution of data may partly explain the variation in findings between studies. The current study adds a novel perspective to the literature by investigating specific meteorological factors such as atmospheric pressure, hours of sunshine, relative humidity, and daily maximum and minimum temperatures as more proximal predictors of self-reported daily mood change in people diagnosed with bipolar disorder...
2017: PloS One
https://www.readbyqxmd.com/read/28277566/positive-traits-in-the-bipolar-spectrum-the-space-between-madness-and-genius
#20
REVIEW
Tiffany A Greenwood
Bipolar disorder is a severe, lifelong mood disorder for which little is currently understood of the genetic mechanisms underlying risk. By examining related dimensional phenotypes, we may further our understanding of the disorder. Creativity has a historical connection with the bipolar spectrum and is particularly enhanced among unaffected first-degree relatives and those with bipolar spectrum traits. This suggests that some aspects of the bipolar spectrum may confer advantages, while more severe expressions of symptoms negatively influence creative accomplishment...
February 2017: Molecular Neuropsychiatry
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