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https://www.readbyqxmd.com/read/29475195/instant-messaging-and-nursing-students-clinical-learning-experience
#1
Christoph Pimmer, Florian Brühlmann, Titilayo Dorothy Odetola, Oluwafemi Dipeolu, Urs Gröhbiel, Ademola J Ajuwon
BACKGROUND: Although learning in clinical settings is a key element of nursing education, for many learners these are challenging developmental contexts often marked by isolation and a lack of belongingness. Despite the massive appropriation of mobile instant messaging (MIM) platforms and the connective properties attendant to them, very little is known about their role in and impact on nursing students' clinical learning experiences. APPROACH AND METHODS: To address this gap, the study, which was part of a multinational research project on the use of mobile social media in health professions education in developing countries, examined the use of the instant messaging platform WhatsApp by nursing students during placements and potential associations with socio-professional indicators...
February 10, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29475180/altered-neural-processing-of-reward-and-punishment-in-adolescents-with-major-depressive-disorder
#2
I Landes, S Bakos, G Kohls, J Bartling, G Schulte-Körne, E Greimel
BACKGROUND: Altered reward and punishment function has been suggested as an important vulnerability factor for the development of Major Depressive Disorder (MDD). Prior ERP studies found evidence for neurophysiological dysfunctions in reinforcement processes in adults with MDD. To date, only few ERP studies have examined the neural underpinnings of reinforcement processing in adolescents diagnosed with MDD. The present event-related potential (ERP) study aimed to investigate neurophysiological mechanisms of anticipation and consumption of reward and punishment in adolescents with MDD in one comprehensive paradigm...
January 31, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29475171/intrahepatic-splenosis-mimicking-hepatic-neoplasia
#3
Gabriel Neves Saad Teles, Paulo Eduardo Zerati Monteiro, Raphael Raphe
INTRODUCTION: Splenosis is defined as the heterotopic autoimplantation of splenic tissue following trauma to or surgery on the spleen. CLINICAL CASE: We present a case of an asymptomatic 73-year-old male in whom hypervascular lesions were detected during routine exams. The patient reported a history of carotid artery surgery and cholecystectomy; he had a laparotomy incision from childhood but was unaware of the reason for it. The patient exhibited slightly elevated carcinoembryonic antigen (CEA) levels...
February 17, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29475154/nursing-students-and-preceptors-experience-of-assessment-during-clinical-practice-a-multilevel-repeated-interview-study-of-student-preceptor-dyads
#4
Karen Johanne Ugland Vae, Maria Engström, Gunilla Mårtensson, Anna Löfmark
Nursing students' learning process during clinical practice is dependent on the quality of their assessment, and the feedback that is given, however an issue that is very little examined. The aim of this study was to investigate student-preceptor dyads and their experiences of mid-course discussions and final assessment. Data were collected through repeated semi-structured individual interviews with 13 dyads close in time to the assessment discussions, and were analyzed by searching for similarities and differences in their experiences...
November 29, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/29475151/ct-angiography-of-the-aorta-in-patients-with-marfan-disease-high-pitch-mdct-at-different-levels-of-tube-voltage-combined-with-sinogram-affirmed-iterative-reconstruction
#5
P Freyhardt, N Solowjowa, G Böning, J Kahn, B Aufmesser, P Haage, F Streitparth
OBJECTIVES: Aim of the study was the comparison of high-pitch dual-source CTA of the aorta acquired with different tube currents and methods of image reconstruction in patients with Marfan Disease (MFS). BACKGROUND: Patients with MFS receive repeatedly CT examinations of the entire aorta what leads to high cumulative lifetime radiation doses. Routine clinical use of low-kV-protocols in combination with iterative reconstruction for imaging of the aorta is still limited although this approach may be of great benefit for patients in need of serial follow-up scans...
February 15, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29475134/inhibition-of-phosphodiesterase-4-by-fcpr16-protects-sh-sy5y-cells-against-mpp-induced-decline-of-mitochondrial-membrane-potential-and-oxidative-stress
#6
Jiahong Zhong, Hui Yu, Chang Huang, Qiuping Zhong, Yaping Chen, Jinfeng Xie, Zhongzhen Zhou, Jiangping Xu, Haitao Wang
Phosphodiesterase 4 (PDE4) is a promising target for the treatment of Parkinson's disease (PD). However, the underlying mechanism has not yet been well elucidated. Additionally, most of current PDE4 inhibitors produce severe nausea and vomiting response in patients, which limit their clinical application. FCPR16 is a novel PDE4 inhibitor with little emetic potential. In the present study, the neuroprotective effect and underlying mechanism of FCPR16 against cellular apoptosis induced by 1-methyl-4-phenylpyridinium (MPP+ ) were examined in SH-SY5Y cells...
February 14, 2018: Redox Biology
https://www.readbyqxmd.com/read/29475104/distress-and-sleep-quality-in-young-amphetamine-type-stimulant-users-with-an-affective-or-psychotic-illness
#7
Jacob J Crouse, Rico S C Lee, Django White, Ahmed A Moustafa, Ian B Hickie, Daniel F Hermens
Misuse of amphetamine-type stimulant (ATS) drugs may disrupt key neurodevelopmental processes in young people and confer protracted neurocognitive and psychopathological harm. ATS users with a co-occurring psychiatric illness are typically excluded from research, reducing generalisability of findings. Accordingly, we conducted a cross-sectional examination of key clinical, sleep, socio-occupational and neurocognitive measures in current, past and never users of ATS drugs who were accessing a youth mental health service (headspace) for affective- or psychotic-spectrum illnesses...
February 17, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29475010/impact-of-a-mental-health-based-primary-care-program-on-emergency-department-visits-and-inpatient-stays
#8
Joshua Breslau, Emily Leckman-Westin, Bing Han, Riti Pritam, Diana Guarasi, Marcela Horvitz-Lennon, Deborah M Scharf, Molly T Finnerty, Hao Yu
OBJECTIVE: Integrating primary care services into specialty mental health clinics has been proposed as a method for improving health care utilization for medical conditions by adults with serious mental illness. This paper examines the impact of a mental health based primary care program on emergency department (ED) visits and hospitalizations. METHOD: The program was implemented in seven New York City outpatient mental health clinics in two waves. Medicaid claims were used to identify patients treated in intervention clinics and a control group of patients treated in otherwise similar clinics in New York City...
February 17, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29474878/long-term-effects-of-brief-hypoxia-due-to-cardiac-arrest-hippocampal-reductions-and-memory-deficits
#9
Vess Stamenova, Raneen Nicola, Judith Aharon-Peretz, Dorith Goldsher, Michael Kapeliovich, Asaf Gilboa
OBJECTIVE: To examine the effects of brief hypoxia (<7 min) due to cardiac arrest on the integrity of the brain and performance on memory and executive functions tasks. METHODS: Acute myocardial infarction (MI) patients after out-of-hospital cardiac arrest (CA) (n = 9), who were deemed neurologically intact on discharge, were compared to matched patients with MI (n = 9). A battery of clinical and experimental memory and executive functions neuropsychological tests were administered and MRI scans for all patients were collected...
February 20, 2018: Resuscitation
https://www.readbyqxmd.com/read/29474865/trajectories-of-plasma-igf-1-igfbp-3-and-their-ratio-in-the-mayo-clinic-study-of-aging
#10
Alexandra M V Wennberg, Clinton E Hagen, Ronald C Petersen, Michelle M Mielke
Insulin-like growth factor 1 (IGF-1) has been associated with osteoporosis, cardiovascular disease, cancer, neurodegenerative diseases, and mortality in middle and older aged adults. Cross-sectionally, IGF-1 decreases with age and levels of IGF-1 are markedly different between individuals. However, little is known about intra-individual trajectories of IGF-1. We examined baseline and serial measures of plasma total IGF-1, IGF binding protein (IGFBP)-3, and their ratio, which is a proxy for bioavailable IGF-1, among 1618 adults, aged 50-95, enrolled in the Mayo Clinic Study of Aging...
February 20, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29474726/recruiting-low-income-postpartum-women-into-two-weight-loss-interventions-in-person-versus-facebook-delivery
#11
Valerie J Silfee, Andrea Lopez-Cepero, Stephenie C Lemon, Barbara Estabrook, Oanh Nguyen, Milagros C Rosal
Several studies, such as the Diabetes Prevention Program (DPP), have provided foundational evidence for the efficacy of lifestyle interventions on weight loss and cardiometabolic prevention. However, translating these interventions to real-world settings and engaging at-risk populations has proven difficult. Social media-delivered interventions have high potential for reaching high-risk populations, but there remains a need to understand the extent to which these groups are interested in social media as a delivery mode...
February 21, 2018: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/29474672/leptomeninges-derived-induced-pluripotent-stem-cells-and-directly-converted-neurons-from-autopsy-cases-with-varying-neuropathologic-backgrounds
#12
Shannon E Rose, Harald Frankowski, Allison Knupp, Bonnie J Berry, Refugio Martinez, Stephanie Q Dinh, Lauren T Bruner, Sherry L Willis, Paul K Crane, Eric B Larson, Thomas Grabowski, Martin Darvas, C Dirk Keene, Jessica E Young
Patient-specific stem cell technology from skin and other biopsy sources has transformed in vitro models of neurodegenerative disease, permitting interrogation of the effects of complex human genetics on neurotoxicity. However, the neuropathologic changes that underlie cognitive and behavioral phenotypes can only be determined at autopsy. To better correlate the biology of derived neurons with age-related and neurodegenerative changes, we generated leptomeningeal cell lines from well-characterized research subjects that have undergone comprehensive postmortem neuropathologic examinations...
February 21, 2018: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/29474639/-valuable-but-incomplete-a-qualitative-study-about-migrants-perspective-on-health-examinations-in-stockholm
#13
Jad Shedrawy, Knut Lönnroth, Asli Kulane
Background: A voluntary health examination is offered to asylum seekers in Sweden with the purpose of detecting infectious diseases and identifying other health needs. This study aimed to explore the organization, content and perceived value of the health examination from the perspective of asylum seekers. Methods: Semi-structured interviews were conducted with 18 migrants recruited from different settings in Stockholm. Data were transcribed verbatim and analysed using thematic analysis in relation to the availability, accessibility, acceptability and quality framework...
February 21, 2018: International Health
https://www.readbyqxmd.com/read/29474547/suicidal-ideation-and-suicide-attempts-among-women-seeking-treatment-for-substance-use-and-trauma-symptoms
#14
Stella M Resko, Sarah Kruman Mountain, Suzanne Browne, David C Kondrat, Michael Kral
Substance use disorders and posttraumatic stress disorder have been associated with suicide. Through secondary analysis of the screening data from the Women and Trauma Study conducted by the National Institute on Drug Abuse Clinical Trials Network, the present study examined rates and correlates of suicidal ideation and suicide attempts among women who sought treatment for substance use and trauma at seven outpatient substance use programs. The sample included women between the ages of 18 and 65 years (M = 39...
February 21, 2018: Health & Social Work
https://www.readbyqxmd.com/read/29474434/microrna-19a-and-microrna-19b-promote-the-malignancy-of-clear-cell-renal-cell-carcinoma-through-targeting-the-tumor-suppressor-rhob
#15
Shaoxi Niu, Xin Ma, Yu Zhang, Yen-Nien Liu, Xufeng Chen, Huijie Gong, Yuanxin Yao, Kan Liu, Xu Zhang
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma, which shows high aggressiveness and lacks biomarkers. RhoB acts as a tumor suppressor that inhibits the progression of ccRCC. In the present study, we examined the effects of oncogenic microRNAs, miR-19a and miR-19b, on RhoB expression in ccRCC cells. The results showed that both miR-19a and miR-19b could directly target the 3'untranslated region (3'UTR) of RhoB, resulting in the reduced expression of RhoB. With RT-PCR analysis, we detected the increased expression of miR-19a and miR-19b in ccRCC tissues compared to adjacent non-tumor renal tissues...
2018: PloS One
https://www.readbyqxmd.com/read/29474418/pattern-of-risks-of-rheumatoid-arthritis-among-patients-using-statins-a-cohort-study-with-the-clinical-practice-research-datalink
#16
Hilda J I de Jong, Jan Willem Cohen Tervaert, Arief Lalmohamed, Frank de Vries, Rob J Vandebriel, Henk van Loveren, Olaf H Klungel, Tjeerd P van Staa
We examined the association between statin use and the risk of rheumatoid arthritis (RA), with special focus on describing the patterns of risks of RA during statin exposure in a large population-based cohort in the United Kingdom. In the Clinical Practice Research Datalink, patients aged ≥40 years with at least one prescription of statins (1995-2009) were selected, and matched by age (+/-5 years), sex, practice and date of first prescription of statins to non-users. The follow-up period of statin use was divided into periods of current, recent and past exposure, with patients moving between these three exposure categories over time...
2018: PloS One
https://www.readbyqxmd.com/read/29474407/predicting-excess-cost-for-older-inpatients-with-clinical-complexity-a-retrospective-cohort-study-examining-cognition-comorbidities-and-complications
#17
Kasia Bail, Brian Draper, Helen Berry, Rosemary Karmel, John Goss
BACKGROUND: Hospital-acquired complications increase length of stay and contribute to poorer patient outcomes. Older adults are known to be at risk for four key hospital-acquired complications (pressure injuries, pneumonia, urinary tract infections and delirium). These complications have been identified as sensitive to nursing characteristics such as staffing levels and level of education. The cost of these complications compared to the cost of admission severity, dementia, other comorbidities or age has not been established...
2018: PloS One
https://www.readbyqxmd.com/read/29474369/a-comparison-of-balance-control-during-stance-and-gait-in-patients-with-inflammatory-and-non-inflammatory-polyneuropathy
#18
Oliver Findling, Rens van der Logt, Krassen Nedeltchev, Lutz Achtnichts, John H J Allum
INTRODUCTION: We compared changes in balance control due to chronic inflammatory demyelinating polyneuropathy (CIDP) and non-inflammatory (non-inf) polyneuropathy (PNP) to each other and with respect to healthy controls (HCs). Differences in patients' subjective impressions of balance capabilities were also compared. METHODS: Balance control of 11 CIDP patients (mean age 61.1±(sd) 11, 8 male) and 10 non-inf PNP patients (mean age 68.5±11.7, all male) was examined and compared to that of 18 age- and gender-matched healthy controls...
2018: PloS One
https://www.readbyqxmd.com/read/29474318/fibroblastic-malignant-peripheral-nerve-sheath-tumour-of-the-uterine-cervix-report-of-a-case-and-literature-review-with-emphasis-on-possible-differential-diagnosis
#19
Valentina Sangiorgio, Vanna Zanagnolo, Giovanni Aletti, Luca Bocciolone, Simone Bruni, Fabio Landoni, Nicoletta Colombo, Angelo Maggioni, Enzo Ricciardi
Cervical sarcomas are rare neoplasms, accounting for <1% of all cervical malignancies and characterized by an aggressive course despite radical excision. We report the clinical and microscopic features of a spindle cell sarcoma arising as a polypoid endocervical mass in a 45-yr-old woman. The neoplasm was characterized by a monotonous, mildly atypical proliferation of spindle cells, displaying a fibrosarcoma-like parallel pattern of highly dense fascicles, growing under the cervical epithelium. Mitotic activity was conspicuous, with up to 40 mitoses per 10 HPF...
February 22, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29474266/recovery-from-schizophrenia-is-it-possible
#20
Antonio Vita, Stefano Barlati
PURPOSE OF REVIEW: Schizophrenia has a heterogeneous range of end states, from severe cases requiring repeated hospitalization to cases in which a single illness episode is followed by complete remission. The purpose of the present review is to examine recent literature on recovery in schizophrenia, focusing on the predictive factors and on the possibility to achieve it. RECENT FINDINGS: Roughly half of schizophrenia patients recovered or significantly improved over the long term, suggesting that functional remission is possible...
February 22, 2018: Current Opinion in Psychiatry
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