keyword
MENU ▼
Read by QxMD icon Read
search

Clinical exam

keyword
https://www.readbyqxmd.com/read/29684916/predictors-of-rapid-cognitive-decline-in-patients-with-mild-to-moderate-alzheimer-disease-a-prospective-cohort-study-with-12-month-follow-up-performed-in-memory-clinics
#1
Achille E Tchalla, Jean-Pierre Clément, Isabelle Saulnier, Betty Beaumatin, Florent Lachal, Caroline Gayot, Anaïs Bosetti, Iléana Desormais, Anaïck Perrochon, Pierre-Marie Preux, Philippe Couratier, Thierry Dantoine
BACKGROUND/AIMS: Alzheimer disease (AD) is particularly devastating, with no cure, no means of prevention, and no proven way to slow progression. AD is associated with the worsening of cognitive function attributable to a variety of factors of which little is known. Our main objective was to determine factors associated with rapid cognitive decline (RCD) in older AD patients. METHODS: We conducted a 12-month, prospective, multi-centre cohort study. Community-living individuals aged ≥65 years with mild-to-moderate AD were included...
April 23, 2018: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/29684892/effects-of-anxiety-and-mood-disorders-on-craving-and-substance-use-among-patients-with-substance-use-disorder-an-ecological-momentary-assessment-study
#2
Melina Fatseas, Fuschia Serre, Joel Swendsen, Marc Auriacombe
BACKGROUND: Despite recognition of the negative impact of psychiatric comorbidity on addictive disorders, the mechanisms underlying this association remain poorly understood. The present investigation applied mobile technologies to examine the effect of comorbid mood or anxiety disorders on craving intensity and substance use within the natural conditions of daily life. METHODS: A total of 159 participants were recruited from a French outpatient addiction clinic and completed two weeks of computerized ambulatory monitoring of daily life experiences using Ecological Momentary Assessment (EMA)...
April 12, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29684837/patient-safety-content-and-delivery-in-pre-registration-nursing-curricula-a-national-cross-sectional-survey-study
#3
Kim Usher, Cindy Woods, Jane Conway, Jackie Lea, Vicki Parker, Fiona Barrett, Eilish O'Shea, Debra Jackson
BACKGROUND: Patient safety is a core principle of health professional practice and as such requires significant attention within undergraduate curricula. However, patient safety practice is complex requiring a broad range of skills and behaviours including the application of sound clinical knowledge within a range of health care contexts and cultures. There is very little research that explores how this is taught within Australian nursing curricula. OBJECTIVES: To examine how Australian nursing curricula address patient safety; identify where and how patient safety learning occurs; and describe who is responsible for facilitating this learning...
April 17, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29684831/dis-integrating-cultural-difference-in-practice-and-communication-a-qualitative-study-of-host-and-migrant-registered-nurse-perspectives-from-new-zealand
#4
Margaret Brunton, Catherine Cook
BACKGROUND: Several earlier studies have provided evidence of the difficulties nurses have had adapting to foreign workplaces, however few have considered wider perspectives of the workplace communication environment. OBJECTIVE: The aim of this study was to examine the viewpoints and experience of both New Zealand qualified nurses and internationally qualified nurses in managing communication within teams and the clinical practice context in an increasingly diverse healthcare workplace in New Zealand...
April 6, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29684805/detecting-a-rare-composite-small-bowel-lymphoma-by-magnetic-resonance-imaging-coincidentally-a-case-report-with-radiological-surgical-and-histopathological-features
#5
M Pezzella, B Brogna, A Romano, F Torelli, G Esposito, M Petrillo, F M Romano, N Di Martino, A Reginelli, R Grassi
INTRODUCTION: Diagnosing lymphoma continues to prove challenging in the clinical practice. Composite lymphoma (CL) is defined by the coexistence of different lymphoma subtypes in the same anatomical location. This condition has seldom been witnessed in the gastrointestinal (GI) tract. We weren't able to find previous cases in the literature about small bowel CL with follicular lymphoma (FL) and classical Hodgkin lymphoma (CHL). Surgery is the treatment of choice to obtain accurate histology, to manage and prevent acute complications...
April 16, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29684794/changes-in-maternal-self-efficacy-postnatal-depression-symptoms-and-social-support-among-chinese-primiparous-women-during-the-initial-postpartum-period-a-longitudinal-study
#6
Xujuan Zheng, Jane Morrell, Kim Watts
BACKGROUND: There are many parenting problems during infancy for Chinese primiparous women. As an important determinant of good parenting, maternal self-efficacy (MSE) should be paid more attention by researchers. At present, the limitations of previous research examining MSE during infancy are that most studies were conducted with a homogeneous sample and there were few studies with Chinese women. Secondly, the trajectory of change in MSE, postnatal depression symptoms and social support for Chinese primiparous women was not clear during the initial postpartum period in earlier studies...
April 11, 2018: Midwifery
https://www.readbyqxmd.com/read/29684789/bipedal-hopping-timed-to-a-metronome-to-detect-impairments-in-anticipatory-motor-control-in-people-with-mild-multiple-sclerosis
#7
Megan C Kirkland, Alice Chen, Matthew B Downer, Brett J Holloway, Elizabeth M Wallack, Evan J Lockyer, Natasha C M Buckle, Courtney L Abbott, Michelle Ploughman
BACKGROUND: People with mild multiple sclerosis (MS) often report subtle deficits in balance and cognition but display no measurable impairment on clinical assessments. We examined whether hopping to a metronome beat had the potential to detect anticipatory motor control deficits among people with mild MS (Expanded Disability Status Scale ≤ 3.5). METHODS: Participants with MS (n = 13), matched controls (n = 9), and elderly subjects (n = 13) completed tests of cognition (Montreal Cognitive Assessment (MoCA)) and motor performance (Timed 25 Foot Walk Test (T25FWT))...
April 13, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29684593/renal-function-n-terminal-pro-b-type-natriuretic-peptide-propeptide-big-endothelin-and-patients-with-heart-failure-and-preserved-ejection-fraction
#8
Ingrid Gergei, Bernhard K Krämer, Hubert Scharnagl, Tatjana Stojakovic, Winfried März
Renal dysfunction may limit the clinical application of NT-proBNP in the diagnosis of heart failure. In general practice, where echocardiography is not readily available, a biomarker for the diagnosis of a heart failure with preserved ejection fraction (HFpEF) would be useful. Since cardiac diseases frequently coincide with renal disease, there is a high need of valid risk stratification methods in patients affected with both. We therefore examined NT-proBNP and another biomarker, Big-Endothelin-1, as a marker of HFpEF in patients with CKD...
April 20, 2018: Peptides
https://www.readbyqxmd.com/read/29684537/genetic-imaging-study-with-tc-99m-trodat-1-spect-in-adolescents-with-adhd-using-oros-methylphenidate
#9
Aynur Pekcanlar Akay, Gamze Çapa Kaya, Samet Kose, Çiğdem Eresen Yazıcıoğlu, Handan Özek Erkuran, Sevay Alşen Güney, Kaya Oğuz, Duygu Keskin, Burak Baykara, Neslihan İnal Emiroğlu, Mine Şencan Eren, Sefa Kızıldağ, Türkan Ertay, Dua Özsoylu, Süha Miral, Hatice Durak, Ali Saffet Gönül, Luis Augusto Rohde
AIM: To examine theeffects on the brain of 2-month treatment withamethylphenidate extended-release formulation (OROS-MPH) using [Tc-99m ] TRODAT-1SPECT in a sample of treatment-naïve adolescents with Attention Deficit/Hyperactivity Disorder (ADHD). In addition, to assess whether risk alleles (homozygosity for 10-repeat allele at the DAT1 gene were associated with alterations in striatal DAT availability. METHODS: Twenty adolescents with ADHD underwent brain single-photon emission computed tomography (SPECT) scans with [Tc-99m ] TRODAT-1 at baseline and two months after starting OROS-MPH treatment with dosages up to 1 mg/kg/day...
April 20, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29684530/supratherapeutic-concentrations-of-cilostazol-inhibits-%C3%AE-amyloid-oligomerization-in-vitro
#10
Hidenobu Shozawa, Tatsunori Oguchi, Mayumi Tsuji, Satoshi Yano, Yuji Kiuchi, Kenjiro Ono
Alzheimer disease (AD) is the most common type of dementia, and is currently incurable. The efficacy of existing treatments for AD such as acetylcholinesterase inhibitors is limited to symptom improvement. Research on disease-modifying therapies (DMTs) has conventionally focused on amelioration of CNS pathogenesis. Two neuropathological changes correlate strongly with AD, the appearance of neurofibrillary tangles containing the microtubule-associated protein tau and extracellular amyloid deposits containing amyloid β-protein (Aβ)...
April 20, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29684514/an-analysis-of-radiation-effects-in-digital-subtraction-angiography-of-intracranial-artery-stenosis
#11
Chaoqun Guo, Xiaolei Shi, Xianhui Ding, Zhiming Zhou
BACKGROUND: Intracranial artery stenosis (IAS) is the most common cause for acute cerebral accidents. Digital subtraction angiography (DSA) is the gold standard to detect IAS, and usually brings excess radiation exposure to examinees and examiners. The artery pathology might influence the interventional procedure, causing a prolonged radiation effects. However, no studies are available on the association between IAS pathology and operational parameters. METHODS: A retrospective analysis was conducted on 93 patients with first-ever stroke/transient ischemic attack (TIA), who received DSA examination within 3 months from onset in this single center...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29684414/examining-variability-in-parent-feeding-practices-within-a-low-income-racially-ethnically-diverse-and-immigrant-population-using-ecological-momentary-assessment
#12
Jerica M Berge, Allan Tate, Amanda Trofholz, Katie Loth, Michael Miner, Scott Crow, Dianne Neumark-Sztainer
BACKGROUND: Current measures of parent feeding practices are typically survey-based and assessed as static/unchanging characteristics, failing to account for fluctuations in these behaviors across time and context. The current study uses ecological momentary assessment to examine variability of, and predictors of parent feeding practices within a low-income, racially/ethnically diverse, and immigrant sample. METHODS: Children ages 5-7 years old and their parents (n = 150 dyads) from six racial/ethnic groups (n = 25 from each; Black/African American, Hispanic, Hmong, Native American, Somali, White) were recruited for this mixed-methods study through primary care clinics...
April 20, 2018: Appetite
https://www.readbyqxmd.com/read/29684318/does-size-matter-when-calculating-the-correct-tidal-volume-for-pediatric-mechanical-ventilation-a-hypothesis-based-on-forced-vital-capacity
#13
Gina J Kim, Christopher J L Newth, Robinder G Khemani, Suzy L Wong, Allan L Coates, Patrick A Ross
BACKGROUND: Tidal volumes standardized to predicted body weight are recommended for adult mechanical ventilation, but children are frequently ventilated using measured body weight. Our goal is to examine the difference in forced vital capacity (FVC ml/kg) using measured compared to predicted body weight in children. METHODS: Retrospective analysis of outpatient pulmonary function tests (PFTs) from two datasets. Dataset one: 6 to 19 year old children undergoing PFTs from the nationally-representative Canadian Health Measures Survey...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29684316/continuous-positive-airway-pressure-adherence-predictors-in-a-randomized-controlled-trial-enriched-with-women-and-minorities
#14
Anna M May, Tarek Gharibeh, Lu Wang, Amanda Hurley, Harneet Walia, Kingman P Strohl, Reena Mehra
BACKGROUND: Suboptimal continuous positive airway pressure (CPAP) adherence in obstructive sleep apnea (OSA) clinical trials involving predominantly Caucasian males limits interpretability and generalizability. We examined predictors of CPAP adherence in a clinical trial enriched with minorities. METHODS: The Sleep Apnea Stress Study - a randomized double-blind, sham-controlled trial of moderate-severe OSA patients - included participants with complete 8-week adherence data (n=138)...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29684308/fracture-healing-and-bone-remodeling-with-human-standard-sized-magnesium-versus-polylactide-co-glycolide-plate-and-screw-systems-using-a-mini-swine-craniomaxillofacial-osteotomy-fixation-model
#15
Benoît Schaller, John Patrik Matthias Burkhard, Madeleine Chagnon, Stefan Beck, Thomas Imwinkelried, Michel Assad
PURPOSE: This study compared the degradation profile, safety, and efficacy of bioresorbable magnesium alloy and polylactide-co-glycolide (PLGA) polymer osteosynthesis systems for the treatment of fractures in a load-sharing maxillofacial environment using a new mini-swine fracture fixation model. MATERIALS AND METHODS: Two types of clinically relevant situations were evaluated in 5 Yucatan miniature pigs. Defined porcine midface osteotomies of the supraorbital rim and zygoma were created and fixed with either a coated magnesium (test animals) or PLGA plate and screw osteosynthesis system (control animals)...
March 31, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29684290/determinants-of-healthy-ageing-and-its-relation-to-10-year-cardiovascular-disease-incidence-the-attica-study
#16
Natasa Kollia, Demosthenes B Panagiotakos, Christina Chrysohoou, Ekavi Georgousopoulou, Dimitrios Tousoulis, Christodoulos Stefanadis, Charalabos Papageorgiou, Christos Pitsavos
OBJECTIVES: The aim of the study was to understand determinants of ageing in relation to future cardiovascular disease (CVD) events at population level, and to explore determinants of healthy ageing and its relation to 10-year CVD incidence among apparently healthy individuals. METHODS: In the context of the ATTICA study 453 apparently healthy men (45±13 years) and 400 women (44±18 years) with complete psychological evaluation were studied and followed during 2002-2012...
March 2018: Central European Journal of Public Health
https://www.readbyqxmd.com/read/29684277/immunopet-imaging-of-endogenous-and-transfected-prolactin-receptor-tumor-xenografts
#17
Sarah M Cheal, Shutian Ruan, Darren R Veach, Valerie A Longo, Blesida J Punzalan, Jiong Wu, Edward K Fung, Marcus P Kelly, Jessica R Kirshner, Jason T Giurleo, George Ehrlich, Amy Q Han, Gavin Thurston, William C Olson, Pat B Zanzonico, Steven M Larson, Jorge A Carrasquillo
OBJECTIVE: Antibodies labeled with positron-emitting isotopes have been used for tumor detection, predicting which patients may respond to tumor antigen-directed therapy, and assessing pharmacodynamic effects of drug interventions. Prolactin receptor (PRLR) is overexpressed in breast and prostate cancers and is a new target for cancer therapy. We evaluated REGN2878, an anti-PRLR monoclonal antibody, as an immunoPET reagent. METHODS: REGN2878 was labeled with Zr-89 after conjugation with desferrioxamine B or labeled with I-131/I-124...
April 23, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29684252/index-of-healthy-aging-in-chinese-older-adults-china-health-and-retirement-longitudinal-study
#18
Chenkai Wu, Anne B Newman, Bi-Rong Dong, Michelle C Odden
OBJECTIVES: To characterize the distribution of an index of healthy aging-the Chinese Healthy Aging Index (CHAI)-in Chinese adults aged 60 and older according to sociodemographic characteristics and geographic region and to examine the association between the CHAI and mortality, disability, and functional limitation over 4 years. DESIGN: Nationally representative cohort study. SETTING: China Health and Retirement Longitudinal Study. PARTICIPANTS: Chinese adults aged 60 and older (N=3,740)...
April 23, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29684209/drug-review-pazopanib
#19
Shingo Miyamoto, Shigenori Kakutani, Yujiro Sato, Akira Hanashi, Yoshitaka Kinoshita, Akira Ishikawa
Pazopanib (Votrient®) is an oral small-molecule multi-kinase inhibitor that primarily inhibits vascular endothelial growth factor receptor-1, -2 and -3, platelet endothelial growth factor receptor-α, and -β, and the stem-cell factor receptor c-kit. In preliminary experiments using angiogenesis models with mice and rabbits, pazopanib inhibited angiogenesis caused by combined vascular endothelial growth factor and basic fibroblast growth factor. Although pazopanib was developed as a therapeutic agent against various tumors, it is currently approved in many countries for advanced soft-tissue sarcoma and renal cell carcinoma...
April 19, 2018: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29684189/correlation-between-perfusion-index-and-crib-score-in-sick-neonates-admitted-to-a-tertiary-center
#20
Jisha Mathew, Chandrakala Bada Shekarappa, Suman Padubidri Nanyam Rao
Objective: The study was to determine the correlation of Perfusion Index (PI) and Clinical Risk Index for Babies (CRIB) score, in assessing the severity of illness in sick neonates. Methods: This was a cross-sectional study conducted at a tertiary care Neonatal Intensive Care Unit (NICU). All eligible neonates, both term and preterm, admitted to the high-dependency unit of the NICU were included, after parental consent. Relevant details of history and examination were collected with a structured proforma...
April 18, 2018: Journal of Tropical Pediatrics
keyword
keyword
23886
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"