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https://www.readbyqxmd.com/read/28798924/diagnostic-performance-of-high-resolution-computed-tomography-in-otosclerosis
#1
Todd Kanzara, Jagdeep Singh Virk
AIM: To determine the sensitivity and specificity of high resolution computed tomography (HRCT) in the diagnosis of otosclerosis. METHODS: A systematic literature review was undertaken to include Level I-III studies (Oxford Centre for Evidenced based Medicine) that utilised HRCT to detect histology confirmed otosclerosis. Quantitative synthesis was then performed. RESULTS: Based on available level III literature, HRCT has a relatively low sensitivity of 58% (95%CI: 49...
July 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28717959/-development-and-validation-of-the-stapesplasty-outcome-test%C3%A2-25-spot-25
#2
S Lailach, T Schenke, I Baumann, H Walter, M Praetorius, T Beleites, T Zahnert, M Neudert
BACKGROUND: Otosclerosis affects health-related quality of life (HRQOL). Until now, measurements have only been performed using audiometric data or non-validated quality of life questionnaires. OBJECTIVE: The objective of this study was to develop the first validated disease-specific HRQOL measuring instrument to determine HRQOL in otosclerosis. MATERIALS AND METHODS: After sequential analysis and item reduction of the initial Stapesplasty Outcome Test 47 (SPOT-47), the SPOT-25 was validated prospectively on 52 otosclerosis patients undergoing stapes surgery...
July 17, 2017: HNO
https://www.readbyqxmd.com/read/28657952/diagnosis-of-superior-semicircular-canal-dehiscence-in-the-presence-of-concomitant-otosclerosis
#3
Michael Yong, Erica Zaia, Brian Westerberg, Jane Lea
OBJECTIVE: To review three patients with concurrent otosclerosis and superior canal dehiscence identified before operative intervention and provide a practical diagnostic approach to this clinical scenario. STUDY DESIGN: Retrospective patient series. SETTING: Tertiary/quaternary referral center. PATIENTS: Individuals with confirmed diagnoses of concurrent otosclerosis and superior semicircular canal dehiscence syndrome...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28555513/high-mobility-group-box-protein-1-expression-in-inflammatory-diseases-of-the-middle-ear
#4
Luisa Maria Bellussi, Carla Vindigni, Serena Cocca, Marie Aimee Gloria Munezero Butorano, Walter Livi, Giulia Corallo, Desiderio Passali
High-mobility group box 1 (HMGB1) is a nuclear non-histone protein, playing a critical role as a mediator between innate and acquired immunity; when released extracellularly, it coordinates the cellular stress response (under necrosis, bacterial lipopolysaccharide stimulation) and acts as an inflammatory marker and cytokine. The aim of the study was to demonstrate whether HMGB1 is over-expressed in chronic middle-ear pathologies and whether the entity of expression and the localization are correlated with the degree of the inflammatory reaction, thus suggesting that HMGB1 may play a crucial role in chronic inflammatory disorders of the middle ear, as already demonstrated in other airway diseases...
March 1, 2017: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/28549773/cochlear-implantation-in-patients-with-otosclerosis-of-the-otic-capsule
#5
Jay Burmeister, Susan Rathgeb, Jacques Herzog
OBJECTIVE: To evaluate outcomes of cochlear implantation of patients with otosclerosis of the otic capsule. STUDY DESIGN: A retrospective case series of 6 patients (7 ears). PATIENTS: 6 patients (7 ears), 5 patients with severe to profound sensorineural hearing loss; 1 patient with mild to profound sensorineural hearing loss, with radiologic evidence of otosclerosis. All patients were adult males, with or without history of stapes surgery...
May 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28542633/new-chamber-stapes-prosthesis-a-preliminary-assessment-of-the-functioning-of-the-prototype
#6
Monika Kwacz, Magdalena Sołyga, Maciej Mrówka, Konrad Kamieniecki
Piston-stapedotomy is the most common method for hearing restoration in patients with otosclerosis. In this study, we have experimentally examined a prototype of a new chamber stapes prosthesis. The prototype was implanted in a human cadaver temporal bone. The round window vibrations before and after implantation were measured for the acoustic signal (90 dB SPL, 0.8-8 kHz) in the external auditory canal. In comparison with a 0.4-mm piston prosthesis, the chamber prosthesis induced significantly higher vibration of the round window, especially for frequencies above 1...
2017: PloS One
https://www.readbyqxmd.com/read/28538469/an-assessment-of-the-clinical-acceptability-of-direct-acoustic-cochlear-implantation-for-adults-with-advanced-otosclerosis-in-the-united-kingdom
#7
Pádraig Thomas Kitterick, Guna Reddy-Kolanu, David Baguley, Jeremey Lavy, Peter Monksfield, Rupan Banga, Jaydip Ray, Ad Snik, Gerard M O'Donoghue
HYPOTHESIS: Assess the clinical acceptability of direct acoustic cochlear implantation for patients with advanced otosclerosis and the support for conducting a controlled trial of its effectiveness in the United Kingdom. BACKGROUND: Emerging evidence supports the efficacy of direct acoustic cochlear implantation in patients with advanced otosclerosis whose needs cannot be managed using the combination of stapes surgery and hearing aids. A controlled trial would provide evidence for its effectiveness and cost-effectiveness to healthcare commissioners...
August 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28532971/clinical-and-audiological-characteristics-of-1000hz-audiometric-notch-patients
#8
Hyun-Min Lee, Seok-Hyun Kim, Jae-Hwan Jung, Se-Joon Oh, Soo-Keun Kong, Il-Woo Lee
PURPOSE: Among the hearing loss patients, we can confirm that the hearing loss of the specific frequency decreases, such as the 2000Hz notch in otosclerosis and the 4000Hz notch (c5-dip) in noise-induced hearing loss. The 1000Hz notch (c3-dip), however, is rarely studied. We fortuitously encountered a group of patients with a 1kHz hearing loss and report it with a review of the literature. METHODS: Otological history, audiogram, diagnosis, occupation, and history of noise exposure were reviewed from charts and telephone interview, and compared between c3-dip and c5-dip patients (n=98)...
April 1, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28485298/the-surgical-treatment-results-of-otosclerosis-at-the-department-of-otolaryngology-silesian-medical-university-in-zabrze-in-years-2000-2010
#9
Gabriela Czerwińska, Wojciech Ścierski, Grzegorz Namysłowski, Grażyna Lisowska, Maciej Misiołek
BACKGROUND: Otosclerosis is a cause of 5-9% of all hearing loss. The most effective treatment of otoslerosis is stapedotomy. AIM: The aim of this study was to evaluate the results of otosclerosis surgical treatment and to examine the impact of disease stage, time of the signs, age and sex on the results. MATERIAL AND METHODS: 105 patients who underwent operation due to otosclerosis at the Department of Otolaryngology University Hospital in Zabrze at the age of 18-65 were analyzed...
April 30, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28439694/modifications-to-a-3d-printed-temporal-bone-model-for-augmented-stapes-fixation-surgery-teaching
#10
Yann Nguyen, Elisabeth Mamelle, Daniele De Seta, Olivier Sterkers, Daniele Bernardeschi, Renato Torres
Functional outcomes and complications in otosclerosis surgery are governed by the surgeon's experience. Thus, teaching the procedure to residents to guide them through the learning process as quickly as possible is challenging. Artificial 3D-printed temporal bones are replacing cadaver specimens in many institutions to learn mastoidectomy, but these are not suitable for middle ear surgery training. The goal of this work was to adapt such an artificial temporal bone to aid the teaching of otosclerosis surgery and to evaluate this tool...
April 24, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28414695/imaging-criteria-to-predict-surgical-difficulties-during-stapes-surgery
#11
Claire Parra, Stéphanie Trunet, Benjamin Granger, Yann Nguyen, Georges Lamas, Daniele Bernardeschi, Rémi Hervochon, Frédéric Tankere
BACKGROUND AND PURPOSE: Stapes surgery for otosclerosis can be challenging if access to the oval window niche is restricted. The aim of this study was to determine the accuracy of the computed tomographic (CT) scan in the evaluation of anatomical distances, and to analyze its reliability in predicting surgical technical difficulties. MATERIAL AND METHODS: A total of 96 patients (101 ears) were enrolled in a prospective study between 2012 and May 2015. During surgery, we evaluated the distance D1 between the stapes and the facial nerve, distance D2 between the promontory and the facial nerve after ablation of the superstructure, and the intraoperative discomfort of the surgeon...
July 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28401629/a-1-470%C3%A2-nm-diode-laser-in-stapedotomy-mechanical-thermal-and-acoustic-effects
#12
Simone P C Koenraads, Tjeerd de Boorder, Wilko Grolman, Digna M A Kamalski
BACKGROUND AND OBJECTIVES: Multiple laser systems have been investigated for their use in stapes surgery in patients with otosclerosis. The diode 1,470 nm laser used in this study is an attractive laser system because it is easily transported and relatively inexpensive in use. This wavelength has relative high absorption in water. This study aimed to investigate the mechanical, thermal, and acoustic effects of the diode 1,470 nm laser on a stapes in an inner ear model. MATERIALS AND METHODS: Experiments were performed in an inner ear model including fresh frozen human stapes...
April 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28350269/review-of-a-single-surgeon-s-stapedotomy-cases-performed-with-a-nickel-titanium-prosthesis-over-a-14-year-period
#13
Natalie Justicz, Kaitlyn F Strickland, Kevin K Motamedi, Douglas E Mattox
CONCLUSION: Stapes surgery with a nickel titanium prosthesis is a safe and well-tolerated procedure that leads to a significant improvement in hearing outcomes. OBJECTIVE: To identify the efficacy and safety of stapedotomy procedures performed with a nickel titanium prosthesis for patients with otosclerosis. METHODS: A review of 431 unique stapedotomies performed over 14 years by a single surgeon at an academic tertiary care center yielded 312 cases with nickel titanium prosthesis that met inclusion criteria of otosclerosis diagnosis, initial surgery in operative ear, and presence of pre-operative and post-operative audiograms...
April 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28319495/endoscopic-stapes-surgery-a-comparison-with-microscopic-surgery
#14
Rhona Sproat, Constantina Yiannakis, Arunachalam Iyer
OBJECTIVE: To investigate postoperative audiological outcomes and complication rates for fully endoscopic and microscopic stapes surgery carried out by a single surgeon in one center. PATIENTS: All patients having undergone endoscopic and non-endoscopic stapes surgery for otosclerosis from September 2009 to August 2016 under a single surgeon. INTERVENTION(S): Stapedotomy using either an operating microscope or endoscope for visualization. Stapedotomy was carried out using a standard approach...
June 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28318477/importance-of-a-dedicated-neuroradiologist-in-reporting-high-resolution-computed-tomography-for-otosclerosis-a-retrospective-comparison-study-of-40-patients
#15
COMPARATIVE STUDY
H Kanona, I Rana, C Offiah, N Patel
OBJECTIVES: This study aimed to compare the reporting of high-resolution computed tomography of temporal bones for otosclerosis by general radiologists and a neuroradiologist within a local National Health Service Trust. METHODS: A retrospective case review of 36 high-resolution temporal bone computed tomography images obtained between 2008 and 2015 from 40 otosclerosis patients (surgically confirmed) was performed in a district general hospital setting. The main outcome measures were correct identification of otosclerosis by high-resolution computed tomography and adherence to the petrous temporal bone imaging protocol...
June 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28306649/secondary-endolymphatic-hydrops
#16
Ashley P O'Connell Ferster, Sebahattin Cureoglu, Nevra Keskin, Michael M Paparella, Huseyin Isildak
HYPOTHESIS: A review of the most recent literature will provide clinicians with an update of secondary endolymphatic hydrops, aiding in diagnosis and treatment of affected patients. BACKGROUND: Secondary endolymphatic hydrops is a pathologic finding of the inner ear resulting in episodic vertigo and intermittent hearing loss. It is a finding for which extensive research is being performed. METHODS: A review of the most recent literature on secondary endolymphatic hydrops was performed using PubMed literature search...
June 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28285827/our-auditory-results-using-the-vibrant-soundbridge-on-the-long-process-of-the-incus-20-years-of-data
#17
Anaïs Grégoire, Jean-Philippe Van Damme, Chantal Gilain, Benoit Bihin, Pierre Garin
OBJECTIVE: After 20 years of experience with different types of middle ear implants, we analyzed our database about the Vibrant Soundbridge (VSB) to know the rate of complications, the effect on the residual hearing and the audiometric gain in our center. METHOD: The study was retrospective and included all VSB implants bound to the long process of the incus in our tertiary medical center between january 1999 and february 2015. We observed the effect of surgery on residual hearing by comparing bone and air conduction thresholds before and after implantation...
March 9, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28285424/stapes-surgery-in-sweden-evaluation-of-a-national-based-register
#18
Karin Strömbäck, Lars Lundman, Andreas Bjorsne, Joakim Grendin, Anna Stjernquist-Desatnik, Ylva Dahlin-Redfors
The aim of the National Quality Registries is to monitor the outcome of healthcare given to patients. The Swedish Quality register for otosclerosis surgery is one of the nine official national registers for ear, nose and throat diseases in Sweden. Since 2004, surgical and audiological results and patient satisfaction scores have been systematically collected from a majority of the ear, nose and throat clinics performing stapes surgery in Sweden. The results of 1688 patients who underwent primary operations for otosclerosis were evaluated for 24 out of totally 26 clinics performing stapes surgery, between 2004 and 2010...
June 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28252592/-the-application-of-the-modern-high-energy-laser-technologies-for-the-surgical-treatment-of-the-patients-presenting-with-otosclerosis
#19
V V Vishnyakov, V M Svistushkin, E V Sin'kov
The objective of the present study was to determine the optimal parameters of radiation of the CO2 laser during the surgical intervention for the treatment of the patients presenting with otosclerosis. The experimental part of the study was carried out with the use of the isolated temporal bones. Under the clinical conditions, the patients with the tympanic and mixed forms of otosclerosis underwent stapedoplasty with the use of the CO2 laser. It was shown that the use of the CO2 laser at different stages of stapedoplasty considerably reduces the risk of development of the post-operative complications...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28247225/update-from-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumours-tumours-of-the-ear
#20
Lester D R Thompson
The 2017 fourth edition of the World Health Organization Classification of Tumours, specifically as it relates to the ear (Chap. 9), has several changes. Importantly, the number of entities has been significantly reduced by omitting tumors or lesions if they do not occur exclusively or predominantly at this site or if they are discussed in detail elsewhere in the book. These entities include: embryonal rhabdomyosarcoma, osteoma, exostosis, angiolymphoid hyperplasia with eosinophilia, Schneiderian papilloma, inverted papilloma, lipoma of the internal auditory canal, hemangioma, hematolymphoid tumors, and secondary tumors...
March 2017: Head and Neck Pathology
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