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https://www.readbyqxmd.com/read/28236352/antazoline-insights-into-drug-induced-electrocardiographic-and-hemodynamic-effects-results-of-the-elephant-ii-substudy
#1
Roman Piotrowski, Joanna Giebułtowicz, Jakub Baran, Agnieszka Sikorska, Dagmara Gralak-Łachowska, Małgorzata Soszyńska, Piotr Wroczyński, Piotr Kułakowski
BACKGROUND: Antazoline is an old antihistaminic and new antiarrhythmic agent with unknown mechanisms of action which recently has been shown to effectively terminate atrial fibrillation. The aim of study was to examine the effects of antazoline on hemodynamic and ECG parameters. METHODS: Antazoline was given intravenously in three 100 mg boluses to 10 healthy volunteers (four males, mean age 40 + 11 years). Hemodynamic and ECG parameters were measured using impedance cardiography [systolic (sBP), diastolic (dBP), mean (mBP) blood pressure, stroke volume (SV), cardiac output (CO), total peripheral resistance (TPR) and heart rate (HR), P wave, PR interval, QRS complex, QT and corrected QT (QTcF) interval]...
February 25, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28225085/aidp-a-novel-n-acyl-homoserine-lactonase-gene-from-antarctic-planococcus-sp
#2
Wah Seng See-Too, Robson Ee, Yan-Lue Lim, Peter Convey, David A Pearce, Wai-Fong Yin, Kok-Gan Chan
Planococcus is a Gram-positive halotolerant bacterial genus in the phylum Firmicutes, commonly found in various habitats in Antarctica. Quorum quenching (QQ) is the disruption of bacterial cell-to-cell communication (known as quorum sensing), which has previously been described in mesophilic bacteria. This study demonstrated the QQ activity of a psychrotolerant strain, Planococcus versutus strain L10.15(T), isolated from a soil sample obtained near an elephant seal wallow in Antarctica. Whole genome analysis of this bacterial strain revealed the presence of an N-acyl homoserine lactonase, an enzyme that hydrolyzes the ester bond of the homoserine lactone of N-acyl homoserine lactone (AHLs)...
February 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28221699/beehive-fences-as-a-multidimensional-conflict-mitigation-tool-for-farmers-coexisting-with-elephants
#3
Lucy E King, Fredrick Lala, Hesron Nzumu, Emmanuel Mwambingu, Iain Douglas-Hamilton
Increasing habitat fragmentation and human population growth in Africa has resulted in an escalation in human-elephant conflict between small-scale farmers and free-ranging African elephants (Loxodonta Africana). In 2012 Kenya Wildlife Service (KWS) implemented the national 10-year Conservation and Management Strategy for the Elephant in Kenya, which includes an action aimed at testing whether beehive fences can be used to mitigate human-elephant conflict. From 2012 to 2015, we field-tested the efficacy of beehive fences to protect 10 0...
February 21, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28221115/mycobacterium-tuberculosis-infection-among-asian-elephants-in-captivity
#4
Gary Simpson, Ralph Zimmerman, Elena Shashkina, Liang Chen, Michael Richard, Carol M Bradford, Gwen A Dragoo, Rhonda L Saiers, Charles A Peloquin, Charles L Daley, Paul Planet, Apurva Narachenia, Barun Mathema, Barry N Kreiswirth
Although awareness of tuberculosis among captive elephants is increasing, antituberculosis therapy for these animals is not standardized. We describe Mycobacterium tuberculosis transmission between captive elephants based on whole genome analysis and report a successful combination treatment. Infection control protocols and careful monitoring of treatment of captive elephants with tuberculosis are warranted.
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28221114/mycobacterium-tuberculosis-infection-in-free-roaming-wild-asian-elephant
#5
Basavegowdanadoddi Marinaik Chandranaik, Beechagondahalli Papanna Shivashankar, Kunigal Srinivasa Umashankar, Poojappa Nandini, Papanna Giridhar, Somenahalli Munivenkatappa Byregowda, Basavegowdanadoddi Marinaik Shrinivasa
Postmortem examination of a wild Asian elephant at Rajiv Gandhi National Park, India, revealed nodular lesions, granulomas with central caseation, and acid-fast bacilli in the lungs. PCR and nucleotide sequencing confirmed the presence of Mycobacterium tuberculosis. This study indicates that wild elephants can harbor M. tuberculosis that can become fatal.
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28221104/mycobacterium-tuberculosis-in-wild-asian-elephants-southern-india
#6
Arun Zachariah, Jeganathan Pandiyan, G K Madhavilatha, Sathish Mundayoor, Bathrachalam Chandramohan, P K Sajesh, Sam Santhosh, Susan K Mikota
We tested 3 ild Asian elephants (Elephas maximus) in southern India and confirmed infection in 3 animals with Mycobacterium tuberculosis, an obligate human pathogen, by PCR and genetic sequencing. Our results indicate that tuberculosis may be spilling over from humans (reverse zoonosis) and emerging in wild elephants.
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28218805/functional-nonredundancy-of-elephants-in-a-disturbed-tropical-forest
#7
Nitin Sekar, Chia-Lo Lee, Raman Sukumar
Conservation efforts are often motivated by the threat of global extinction. Yet if conservationists had more information suggesting that the local extirpation of individual species could lead to undesirable ecological effects, conservationists might more frequently attempt to protect or restore such species across their range even if they are not in danger of global extinction. Scientists have seldom measured or quantitatively predicted the functional consequences of species loss, even for large, extinction-prone species that theory suggests should be functionally unique...
February 20, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28207692/how-to-get-elephants-to-buzz-off
#8
John R Platt
No abstract text is available yet for this article.
February 14, 2017: Scientific American
https://www.readbyqxmd.com/read/28202583/acoustic-measurements-of-post-dive-cardiac-responses-in-southern-elephant-seals-mirounga-leonina-during-surfacing-at-sea
#9
Louise Day, Joffrey Jouma'a, Julien Bonnel, Christophe Guinet
Measuring physiological data in free-ranging marine mammals remains challenging, owing to their far-ranging foraging habitat. Yet, it is important to understand how these divers recover from effort expended underwater, as marine mammals can perform deep and recurrent dives. Among them, southern elephant seals (Mirounga leonina) are one of the most extreme divers, diving continuously at great depth and for long duration while travelling over large distances within the Southern Ocean. To determine how they manage post-dive recovery, we deployed hydrophones on four post-breeding female southern elephant seals...
February 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28199322/keas-perform-similarly-to-chimpanzees-and-elephants-when-solving-collaborative-tasks
#10
Megan Heaney, Russell D Gray, Alex H Taylor
Cooperation between individuals is one of the defining features of our species. While other animals, such as chimpanzees, elephants, coral trout and rooks also exhibit cooperative behaviours, it is not clear if they think about cooperation in the same way as humans do. In this study we presented the kea, a parrot endemic to New Zealand, with a series of tasks designed to assess cooperative cognition. We found that keas were capable of working together, even when they had to wait for their partner for up to 65 seconds...
2017: PloS One
https://www.readbyqxmd.com/read/28191647/flexible-conceptual-combination-electrophysiological-correlates-and-consequences-for-associative-memory
#11
Heather D Lucas, Ryan J Hubbard, Kara D Federmeier
When meaningful stimuli such as words are encountered in groups or pairs (e.g., "elephant-ferry"), they can be processed either separately or as an integrated concept ("an elephant ferry"). Prior research suggests that memory for integrated associations is supported by different mechanisms than is memory for nonintegrated associations. However, little is known about the neurocognitive mechanisms that support the integration of novel stimulus pairs. We recorded ERPs while participants memorized sequentially presented, unrelated noun pairs using a strategy that either did or did not involve attempting to construct coherent definitions...
February 13, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28188622/the-optic-nerve-superior-colliculus-visual-thalamus-and-primary-visual-cortex-of-the-northern-elephant-seal-mirounga-angustirostris-and-california-sea-lion-zalophus-californianus
#12
Emily C Turner, Eva K Sawyer, Jon H Kaas
The northern elephant seal (Mirounga angustirostris) and California sea lion (Zalophus californianus) are members of a diverse clade of carnivorous mammals known as pinnipeds. Pinnipeds are notable for their large, ape-sized brains, yet little is known about their central nervous system. Both the northern elephant seal and California sea lion spend most of their lives at sea, but each also spends time on land to breed and give birth. These unique coastal niches may be reflected in specific evolutionary adaptations to their sensory systems...
February 11, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28186107/blubber-transcriptome-response-to-acute-stress-axis-activation-involves-transient-changes-in-adipogenesis-and-lipolysis-in-a-fasting-adapted-marine-mammal
#13
J I Khudyakov, C D Champagne, L M Meneghetti, D E Crocker
Stress can compromise an animal's ability to conserve metabolic stores and participate in energy-demanding activities that are critical for fitness. Understanding how wild animals, especially those already experiencing physiological extremes (e.g. fasting), regulate stress responses is critical for evaluating the impacts of anthropogenic disturbance on physiology and fitness, key challenges for conservation. However, studies of stress in wildlife are often limited to baseline endocrine measurements and few have investigated stress effects in fasting-adapted species...
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28180119/nonemergent-patients-in-the-emergency-department-an-ethnographic-study
#14
Amir Mirhaghi, Abbas Heydari, Mohsen Ebrahimi, Mohsen Noghani Dokht Bahmani
BACKGROUND: Triage in the interactive atmosphere of the emergency department (ED) has been described as complex and challenging. Nonemergent ED visits have been accompanied by ethical and legal conflicts. OBJECTIVES: The aim of this study was to gain an understanding of ED nurses' practice regarding triage of nonemergent patients. PATIENTS AND METHODS: Focused micro-ethnography based on Spradley's developmental research sequence (DRS) was used...
September 2016: Trauma Monthly
https://www.readbyqxmd.com/read/28180096/the-frozen-elephant-trunk-technique-european-association-for-cardio-thoracic-surgery-position-and-bologna-experience
#15
REVIEW
Luca Di Marco, Antonio Pantaleo, Alessandro Leone, Giacomo Murana, Roberto Di Bartolomeo, Davide Pacini
Complex lesions of the thoracic aorta are traditionally treated in 2 surgical steps with the elephant trunk technique. A relatively new approach is the frozen elephant trunk (FET) technique, which potentially allows combined lesions of the thoracic aorta to be treated in a 1-stage procedure combining endovascular treatment with conventional surgery using a hybrid prosthesis. These are very complex and time-consuming operations, and good results can be obtained only if appropriate strategies for myocardial, cerebral, and visceral protection are adopted...
February 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28157639/distinguishing-real-from-fake-ivory-products-by-elemental-analyses-a-bayesian-hybrid-classification-method
#16
Kittisak Buddhachat, Janine L Brown, Chatchote Thitaram, Sarisa Klinhom, Korakot Nganvongpanit
As laws tighten to limit commercial ivory trading and protect threatened species like whales and elephants, increased sales of fake ivory products have become widespread. This study describes a method, handheld X-ray fluorescence (XRF) as a noninvasive technique for elemental analysis, to differentiate quickly between ivory (Asian and African elephant, mammoth) from non-ivory (bones, teeth, antler, horn, wood, synthetic resin, rock) materials. An equation consisting of 20 elements and light elements from a stepwise discriminant analysis was used to classify samples, followed by Bayesian binary regression to determine the probability of a sample being 'ivory', with complementary log log analysis to identify the best fit model for this purpose...
January 21, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28157638/probing-human-brain-evolution-and-development-in-organoids
#17
REVIEW
Stefano L Giandomenico, Madeline A Lancaster
Expansion of the neocortex is thought to underpin the higher cognitive abilities of a number of mammalian lineages, such as cetaceans, elephants, and primates, with humans exhibiting a particularly enlarged and dense cerebral cortex. However, the evolutionary and developmental mechanisms that led to this expansion are not well-understood and limited to correlative observations. Historically, this has been due to technical and ethical limitations owing to the intractability of various species for functional studies...
January 31, 2017: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/28156552/the-elephant-in-the-room-facilitating-conversations-about-advanced-cancer-between-patients-and-their-spouses
#18
Laura FIsh, Hope Elizabeth Uronis, Yousuf Zafar, Karen E Steinhauser
: 233 Background: Interventions to enhance couples' communication about cancer-related issues can lead to benefits for patients, spouses, and their relationships. We recently conducted a pilot study testing a couples communication skills training (CCST) intervention targeted to couples in which one partner had advanced GI cancer, a population who may need particular help addressing difficult and emotionally-laden topics related to life-limiting illness. Results of quantitative analyses suggested that the intervention was effective in improving relationship satisfaction for these couples...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28139063/lignin-depolymerisation-and-lignocellulose-fractionation-by-solvated-electrons-in-liquid-ammonia
#19
Pepijn Prinsen, Anand Narani, Gadi Rothenberg
We explored the depolymerisation of several lignins in liquid ammonia at relatively high temperatures and pressures (120 °C and 88 bar). Five different lignins were tested: Indulin AT kraft, Protobind 1000 soda, wheat straw organosolv, poplar organosolv and elephant grass-milled wood lignin (EG MWL). In pure liquid ammonia, all lignins underwent slow incorporation of nitrogen into their structure, resulting in higher molecular weight and polydispersity index. Subsequently, we show a reductive depolymerisation by solvated electrons at room temperature by adding sodium metal to the liquid ammonia without any external hydrogen donor...
January 31, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28131431/the-standardized-concept-of-moderate-to-mild-%C3%A2-28%C3%A2-c-systemic-hypothermia-during-selective-antegrade-cerebral-perfusion-for%C3%A2-all-comers-in-aortic-arch-surgery-single-center-experience-in-587-consecutive-patients-over-a-15-year-period
#20
Ali El-Sayed Ahmad, Nestoras Papadopoulos, Petar Risteski, Anton Moritz, Andreas Zierer
BACKGROUND: Whether selective antegrade cerebral perfusion (ACP) during moderate-to-mild systemic hypothermia (≥28°C) is applicable to aortic arch surgery without restrictions including the emergency setting of an acute type A aortic dissection or extensive total arch procedures such as elephant and frozen elephant trunk techniques is an ongoing subject of controversy. METHODS: Between January 2000 and January 2015, 587 consecutive all-comers underwent aortic arch surgery at our institution uniformly applying selective ACP (unilateral: n = 393 [67%]; bilateral: n = 194 [33%]) during moderate-to-mild systemic hypothermia (28...
January 25, 2017: Annals of Thoracic Surgery
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