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https://www.readbyqxmd.com/read/29471372/a-multistate-outbreak-of-human-salmonella-agona-infections-associated-with-consumption-of-fresh-whole-papayas-imported-from-mexico-united-states-2011
#1
Adamma Mba-Jonas, Wright Culpepper, Thomas Hill, Venessa Cantu, Julie Loera, Julie Borders, Lori Saathoff-Huber, Johnson Nsubuga, Ingrid Zambrana, Shannon Dalton, Ian Williams, Karen P Neil
Background: Nontyphoidal Salmonella causes ~1 million food-borne infections annually in the United States. We began investigating a multistate outbreak of Salmonella serotype Agona infections in April 2011. Methods: A case was defined as infection with the outbreak strain of Salmonella Agona occurring between 1 January and 25 August 2011. We developed hypotheses through iterative interviews. Product distribution analyses and traceback investigations were conducted...
February 19, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29471266/genetic-characterization-of-respiratory-syncytial-virus-highlights-a-new-ba-genotype-and-emergence-of-the-on1-genotype-in-lyon-france-between-2010-and-2014
#2
Alexandre Gaymard, Maude Bouscambert-Duchamp, Maxime Pichon, Emilie Frobert, Julien Vallee, Bruno Lina, Jean-Sébastien Casalegno, Florence Morfin
BACKGROUND: Respiratory syncytial virus (RSV) is a well-recognized cause of respiratory tract infections. Based on G gene variations, 11 RSV-A and 36 RSV-B genotypes have been described to date. The ON1 genotype was detected in Ontario in 2010 and subsequently reported in several countries. OBJECTIVES: The objective of the present study was to investigate for the first time the RSV epidemiology and genotype diversity in France between 2010 and 2014. STUDY DESIGN: All respiratory samples received from patients with influenza-like illness or respiratory tract infection were screened for RSV infection by RT-PCR...
February 6, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29471261/regulation-of-cortical-and-peripheral-gch1-expression-and-biopterin-levels-in-schizophrenia-spectrum-disorders
#3
James D Clelland, Laura L Read, Jennifer Smeed, Catherine L Clelland
Tetrahydrobiopterin (BH4 ) is an essential cofactor for dopamine, serotonin and nitric oxide synthesis. Deficits of plasma total biopterin (a measure of BH4 ) have been described in schizophrenia and schizoaffective disorder. GCH1 encodes the first and rate-limiting enzyme in BH4 synthesis. Peripheral GCH1 expression is lower in first episode psychosis patients versus controls, and we hypothesized that a GCH1 promoter polymorphism associated with psychiatric illness, contributes to regulation of both GCH1 expression and BH4 levels...
February 8, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29471226/examining-effects-of-medical-cannabis-narratives-on-beliefs-attitudes-and-intentions-related-to-recreational-cannabis-a-web-based-randomized-experiment
#4
Sharon R Sznitman, Nehama Lewis
BACKGROUND: This experimental study tests effects of exposure to video narratives about successful symptom relief with Medical Cannabis (MC) on attitudes, beliefs, and intentions related to recreational cannabis use. METHODS: Patient video testimonials were modeled after those found in extant media coverage. Israeli participants (N = 396) recruited through an online survey company were randomly assigned to view a narrative or a non-narrative video containing equivalent information about MC...
January 31, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29470807/longitudinal-effects-of-adjuvant-endocrine-therapy-on-the-quality-of-life-of-post-menopausal-women-with-non-metastatic-er-breast-cancer-a-systematic-review
#5
REVIEW
Hong Xiao, Xinyi Jiang, Cheng Chen, Alberto J Montero, Vakaramoko Diaby
BACKGROUND: Anti-estrogen (ER) endocrine therapy is an effective treatment strategy in reducing breast cancer mortality. This therapy has a better therapeutic index than chemotherapy but can still affect patients' quality of life (QOL) over time. OBJECTIVE: The objectives of this systematic review were to (1) describe QOL instruments used in ER-positive (ER+) non-metastatic breast cancer trials and (2) document the longitudinal effects of adjuvant endocrine therapy on the QOL of post-menopausal women with ER+ non-metastatic breast cancer...
February 22, 2018: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29470341/clinical-updates-in-women-s-health-care-summary-arthritis
#6
Debendra Pattanaik
Arthritis is a commonly encountered problem in daily clinical practice, and with an aging population it will be as prevalent as any other chronic illness, such as diabetes mellitus, hypertension, and hypercholesterolemia. Obstetrician-gynecologists often encounter patients with arthritic symptoms in their practices. They may find it challenging to identify the underlying cause of arthritis and provide recommendations, as well as provide obstetric care to patients with known arthritis. The monograph will discuss common forms of arthritis, diagnostic testing and appropriate management, and referral of patients who need specialized care...
March 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29470233/can-a-nomogram-help-to-predict-the-overall-and-cancer-specific-survival-of-patients-with-chondrosarcoma
#7
Kehan Song, Xiao Shi, Hongli Wang, Fei Zou, Feizhou Lu, Xiaosheng Ma, Xinlei Xia, Jianyuan Jiang
BACKGROUND: Many factors have been reported to be associated with the prognosis of patients with chondrosarcoma, but clinicians have few tools to estimate precisely an individual patient's likelihood of surviving the illness. We therefore sought to develop effective nomograms to better estimate the survival of patients with chondrosarcoma. QUESTIONS/PURPOSES: (1) Which clinicopathologic features are independent prognostic factors for patients with chondrosarcoma? (2) Can we develop a nomogram to predict 3- and 5-year overall and cancer-specific survival of individual patients with chondrosarcoma based on personalized information? METHODS: We collected information on patients diagnosed with chondrosarcoma between 1988 and 2011 from the Surveillance, Epidemiology, and End Results (SEER) database...
February 21, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29470127/telemedicine-physical-examination-utilizing-a-consumer-device-demonstrates-poor-concordance-with-in-person-physical-examination-in-emergency-department-patients-with-sore-throat-a-prospective-blinded-study
#8
Moneeb Akhtar, Paul G Van Heukelom, Azeemuddin Ahmed, Rachel D Tranter, Erinn White, Nathaniel Shekem, David Walz, Catherine Fairfield, J Priyanka Vakkalanka, Nicholas M Mohr
BACKGROUND: Telemedicine allows patients to connect with healthcare providers remotely. It has recently expanded to evaluate low-acuity illnesses such as pharyngitis by using patients' personal communication devices. The purpose of our study was to compare the telemedicine-facilitated physical examination with an in-person examination in emergency department (ED) patients with sore throat. MATERIALS AND METHODS: This was a prospective, observational, blinded diagnostic concordance study of patients being seen for sore throat in a 60,000-visit Midwestern academic ED...
February 22, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29469794/inflamed-actinic-keratoses-associated-with-pemetrexed-and-carboplatin-therapy
#9
Jimmy Lam, Samantha R Ellis, Raja K Sivamani
Eruptive actinic keratosis (AK) consequent to systemic chemotherapy can be confused with drug allergies. We present the first case of inflamed AKs in one patient after receiving combination therapy with pemetrexed and carboplatin.A 68-year-old woman with non-small cell lung adenocarcinoma (NSCLC) presented with numerous pruritic ill-defined, gritty, erythematous papules consistent with AKs on her upper chest, upper back, and arms two weeks after completing the first cycle of combination therapy with carboplatin and pemetrexed...
October 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469667/10-year-outcome-of-suicidal-behavior-in-borderline-personality-disorder
#10
Paul H Soloff, Laurel Chiappetta
Prospective predictors of suicide attempts were assessed in 118 subjects with borderline personality disorder (BPD) after 10 or more years of follow-up. Mean (SD) time to follow-up was 14.4 (4.7) years. Subjects were predominately female (78.8%), Caucasian (81.4%), and of lower socioeconomic status. Initial recruitment was evenly balanced between inpatient, outpatient, and non-patient (community) sources. In the 10-year interval, 55 subjects (46.6%) attempted suicide. Compared to baseline, suicidal ideation, number of attempts, and non-suicidal self-injury diminished markedly...
February 22, 2018: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29469637/mental-illness-in-sweden-1896-1905-reflected-through-case-records-from-a-local-general-hospital
#11
Malin Appelquist, Louise Brådvik, Marie Åsberg
Mental illness in a hospital in a medium-sized town in Sweden was studied. Consecutive case records from 1896 to 1905, and also from 2011, were selected. In the historical sample, neurasthenia was the most common diagnosis, followed by affective disorders and alcohol abuse. ICD-10 diagnoses corresponded well with the historical diagnoses. Melancholia resembled modern criteria for depression. Mania, insania simplex and paranoia indicated more severe illness. Abuse was more common among men and hysteria among women...
February 1, 2018: History of Psychiatry
https://www.readbyqxmd.com/read/29469547/workload-and-severity-of-illness-of-patients-on-intensive-care-units-with-available-intermediate-care-units-a-multicentre-cohort-study
#12
Uwe Hamsen, Rolf Lefering, Christian Fisahn, Thomas A Schildhauer, Chistian Waydhas
BACKGROUND: Intermediate care units (IMCU) are established in many hospitals to better match the requirements of patient care with respect to their personnel, equipment and other resources. This should relieve intensive care unit (ICU) capacities for more severely ill patients and reduce readmissions to ICU. This study was conducted to investigate the effects of IMCU use on ICU populations. METHODS: This is a retrospective analysis of the German National Registry of Intensive Care from the years 2000 to 2010...
February 15, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29469365/-epidemic-characteristics-of-imported-falciparum-malaria-in-huai-an-city
#13
Jia Cong-Ying, Wang Wei-Ming, Yang Wen-Zhou, Gao Hong-Xia
OBJECTIVE: To understand the situation and epidemic characteristics of imported falciparum malaria in Huai'an City from 2010 to 2016, so as to provide the evidence for formulating the prevention and control strategies of imported falciparum malaria in the city. METHODS: The epidemic data of imported falciparum malaria in Huai'an City from 2010 to 2016 were analyzed by using the descriptive epidemiological method. RESULTS: A total of 308 malaria cases were reported in Huai'an City from 2010 to 2016 with the average annual incidence of 0...
July 28, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469010/effect-of-blood-thiamine-concentrations-on-mortality-influence-of-nutritional-status
#14
Heitor Pons Leite, Lúcio Flávio Peixoto de Lima, José Augusto de A C Taddei, Ângela Tavares Paes
OBJECTIVE: To test the hypothesis that low blood thiamine concentrations in malnourished critically ill children are associated with higher risk of 30-d mortality. METHODS: Prospective cohort study in 202 consecutively admitted children who had whole blood thiamine concentrations assessed on admission and on days 5 and 10 of intensive care unit (ICU) stay. The primary outcome variable was 30-d mortality. Mean blood thiamine concentrations within the first 10 d of ICU stay, age, sex, malnutrition, C-reactive protein concentration, Pediatric Index of Mortality 2 score, and severe sepsis/septic shock were the main potential exposure variables for outcome...
December 7, 2017: Nutrition
https://www.readbyqxmd.com/read/29468674/mental-health-of-long-term-survivors-of-childhood-and-young-adult-cancer-a-systematic-review
#15
REVIEW
Amanda J Friend, Richard G Feltbower, Emily J Hughes, Kristian P Dye, Adam W Glaser
Childhood cancer is increasing in prevalence whilst survival rates are improving. The prevalence of adult survivors of childhood cancer is consequently increasing. Many survivors suffer long-term consequences of their cancer treatment. Whilst many of these are well documented, relatively little is known about the mental health of survivors of childhood cancer. This article aimed to describe the prevalence and spectrum of mental health problems found in adult survivors of childhood cancer using a systematic review methodology...
February 22, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29468437/young-adults-diagnosed-with-hodgkin-lymphoma-are-at-risk-of-relapsing-late-a-comprehensive-analysis-of-late-relapse-in-hodgkin-lymphoma
#16
László Pinczés, Zsófia Miltényi, Árpád Illés
PURPOSE: Majority of relapses in Hodgkin lymphoma (HL) occur within 3 years after initial treatment, late relapses (LR), happening 5 or more years after first diagnosis is rare events. Neither clinical characteristics, risk factors, nor optimal treatment is well described for LR patients. Our aim was to provide a comprehensive analysis on the LR of HL to outline a patient population at risk of relapsing late. PATIENTS AND METHODS: 637 HL patients were treated at the University of Debrecen between 1981 and 2010...
February 21, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29468419/establishment-of-an-italian-chronic-migraine-database-a-multicenter-pilot-study
#17
Piero Barbanti, L Fofi, S Cevoli, P Torelli, C Aurilia, G Egeo, L Grazzi, D D'Amico, G C Manzoni, P Cortelli, F Infarinato, N Vanacore
To optimize chronic migraine (CM) ascertainment and phenotype definition, provide adequate clinical management and health care procedures, and rationalize economic resources allocation, we performed an exploratory multicenter pilot study aimed at establishing a CM database, the first step for developing a future Italian CM registry. We enrolled 63 consecutive CM patients in four tertiary headache centers screened with face-to-face interviews using an ad hoc dedicated semi-structured questionnaire gathering detailed information on life-style, behavioral and socio-demographic factors, comorbidities, and migraine features before and after chronicization and healthcare resource use...
February 22, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29468417/eliciting-the-experiences-of-the-adolescent-parent-dyad-following-critical-care-admission-a-pilot-study
#18
Dora Wood, Sophie Geoghegan, Padmanabhan Ramnarayan, Peter J Davis, John V Pappachan, Sarah Goodwin, Jo Wray
Critically ill adolescents are usually treated on intensive care units optimised for much older adults or younger children. The way they access and experience health services may be very different to most adolescent service users, and existing quality criteria may not apply to them. The objectives of this pilot study were, firstly, to determine whether adolescents and their families were able to articulate their experiences of their critical care admission and secondly, to identify the factors that are important to them during their intensive care unit (ICU) or high dependency unit (HDU) stay...
February 21, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29468373/exploring-symptom-severity-illness-perceptions-coping-styles-and-well-being-in-gastroparesis-patients-using-the-common-sense-model
#19
Sally Woodhouse, Geoff Hebbard, Simon R Knowles
AIMS: This study aimed to examine the relationships between gastroparesis symptom severity, illness perceptions, coping styles, quality of life (QoL), and psychological distress in patients with gastroparesis, guided by the common sense model. METHODS: One hundred and seventy-nine adults with gastroparesis (165 females, 14 males; mean age 41.82 years) completed an online questionnaire. The Gastroparesis Cardinal Symptom Index was used to measure gastroparesis symptom severity, QoL was explored using the PAGI-QOL, illness perceptions were measured using the Brief Illness Perception Questionnaire, the Carver Brief COPE scale assessed coping styles, and psychological distress was investigated using the DASS21...
February 22, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29468335/use-of-speckle-tracking-strain-in-preload-dependent-patients-need-for-cautious-interpretation
#20
C Nafati, M Gardette, M Leone, L Reydellet, V Blasco, A Lannelongue, F Sayagh, S Wiramus, F Antonini, J Albanèse, L Zieleskiewicz
BACKGROUND: In critical patients, left ventricular ejection fraction and fractional shortening are used to reflect left ventricular systolic function. An emerging technique, two-dimensional-strain echocardiography, allows assessment of the left ventricle systolic longitudinal deformation (global longitudinal strain) and the speed at which this deformation occurs (systolic strain rate). This technique is of increasing use in critical patients in intensive care units and in the peri-operative period where preload constantly varies...
February 21, 2018: Annals of Intensive Care
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