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Integrated information theory

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https://www.readbyqxmd.com/read/28718773/mouse-epileptic-seizure-detection-with-multiple-eeg-features-and-simple-thresholding-technique
#1
Quang M Tieng, Ashwin Anbazhagan, Min Chen, David Charles Reutens
Epilepsy is a common neurological disorder characterized by recurrent, unprovoked seizures. The search for new treatments for seizures and epilepsy relies upon studies in animal models of epilepsy. To capture data on seizures, many applications require prolonged electroencephalography (EEG) with recordings that generate voluminous data. The desire for efficient evaluation of these recordings motivates the development of automated seizure detection algorithms. Approach: A new seizure detection method is proposed, based on multiple features and a simple thresholding technique...
July 18, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28716931/combining-experimental-and-simulation-data-of-molecular-processes-via-augmented-markov-models
#2
Simon Olsson, Hao Wu, Fabian Paul, Cecilia Clementi, Frank Noé
Accurate mechanistic description of structural changes in biomolecules is an increasingly important topic in structural and chemical biology. Markov models have emerged as a powerful way to approximate the molecular kinetics of large biomolecules while keeping full structural resolution in a divide-and-conquer fashion. However, the accuracy of these models is limited by that of the force fields used to generate the underlying molecular dynamics (MD) simulation data. Whereas the quality of classical MD force fields has improved significantly in recent years, remaining errors in the Boltzmann weights are still on the order of a few [Formula: see text], which may lead to significant discrepancies when comparing to experimentally measured rates or state populations...
July 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28711760/investigation-of-the-binding-free-energies-of-fda-approved-drugs-against-subtype-b-and-c-sa-hiv-pr-oniom-approach
#3
Z K Sanusi, T Govender, G E M Maguire, S B Maseko, J Lin, H G Kruger, B Honarparvar
Human immune virus subtype C is the most widely spread HIV subtype in Sub-Sahara Africa and South Africa. A profound structural insight on finding potential lead compounds is therefore necessary for drug discovery. The focus of this study is to rationalize the nine Food and Drugs Administration (FDA) HIV antiviral drugs complexed to subtype B and C-SA PR using ONIOM approach. To achieve this, an integrated two-layered ONIOM model was used to optimize the geometrics of the FDA approved HIV-1 PR inhibitors for subtype B...
June 29, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28709377/combining-graphical-and-analytical-methods-with-molecular-simulations-to-analyze-time-resolved-fret-measurements-of-labeled-macromolecules-accurately
#4
Thomas-Otavio Peulen, Oleg Opanasyuk, Claus A M Seidel
Förster resonance energy transfer (FRET) measurements from a donor, D, to an acceptor, A, fluorophore are frequently used in vitro and in live cells to reveal information on the structure and dynamics of DA-labeled macromolecules. Accurate descriptions of FRET-measurements by molecular models are complicated because the fluorophores are usually coupled to the macromolecule via flexible long linkers allowing for diffusional exchange between multiple states with different fluorescence properties caused by distinct environmental quenching, dye mobilities, and variable DA-distances...
July 14, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28705157/ward-social-workers-views-of-what-facilitates-or-hinders-collaboration-with-specialist-palliative-care-team-social-workers-a-grounded-theory
#5
Janice Firn, Nancy Preston, Catherine Walshe
BACKGROUND: Inpatient, generalist social workers in discharge planning roles work alongside specialist palliative care social workers to care for patients, often resulting in two social workers being concurrently involved in the same patient's care. Previous studies identifying components of effective collaboration, which impacts patient outcomes, care efficiency, professional job satisfaction, and healthcare costs, were conducted with nurses and physicians but not social workers. This study explores ward social workers' perceptions of what facilitates or hinders collaboration with palliative care social workers...
July 14, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28700236/on-the-equivalence-of-the-floquet-magnus-and-fer-expansions-to-investigate-the-dynamics-of-a-spin-system-in-the-three-level-system
#6
Eugene Stephane Mananga
In this work, we investigated the orders to which the Floquet-Magnus expansion (FME) and Fer expansion (FE) are equivalent or different for the three-level system. Specifically, we performed the third-order calculations of both approaches based on elegant integrations formalism. We present an important close relationship between the Floquet-Magnus and Fer expansions. As the propagator from the FME takes the form of the evolution operator which removes the constraint of a stroboscopic observation, we appreciated the effects of time-evolution under Hamiltonians with different orders separately...
July 12, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28695705/all-drinking-is-not-equal-how-a-social-practice-theory-lens-could-enhance-public-health-research-on-alcohol-and-other-health-behaviours
#7
Petra Sylvia Meier, Alan Warde, John Holmes
BACKGROUND: The social meanings, settings and habitual nature of health-related activities and their integration into our daily lives are often overlooked in quantitative public health research. This reflects an overly individualized approach to epidemiological surveillance and evaluations of public health interventions, based on models of behaviour that are rooted in social cognition and rational choice theories. This paper calls for a new approach to alcohol epidemiology and intervention research informed by theories of practice...
July 11, 2017: Addiction
https://www.readbyqxmd.com/read/28694253/implementing-the-compassion-intervention-a-model-for-integrated-care-for-people-with-advanced-dementia-towards-the-end-of-life-in-nursing-homes-a-naturalistic-feasibility-study
#8
Kirsten J Moore, Bridget Candy, Sarah Davis, Anna Gola, Jane Harrington, Nuriye Kupeli, Victoria Vickerstaff, Michael King, Gerard Leavey, Irwin Nazareth, Rumana Z Omar, Louise Jones, Elizabeth L Sampson
BACKGROUND: Many people with dementia die in nursing homes, but quality of care may be suboptimal. We developed the theory-driven 'Compassion Intervention' to enhance end-of-life care in advanced dementia. OBJECTIVES: To (1) understand how the Intervention operated in nursing homes in different health economies; (2) collect preliminary outcome data and costs of an interdisciplinary care leader (ICL) to facilitate the Intervention; (3) check the Intervention caused no harm...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28689552/breastfeeding-is-natural-but-not-the-cultural-norm-a-mixed-methods-study-of-first-time-breastfeeding-african-american-mothers-participating-in-wic
#9
Julia H Kim, Barbara H Fiese, Sharon M Donovan
OBJECTIVE: Identify facilitators, barriers, and needs to increase breastfeeding (BF) support. DESIGN: Semistructured interviews based on the Theory of Planned Behavior, Iowa Infant Feeding Attitude Scale, and Breastfeeding Self-Efficacy Scale-Short Form to measure attitudes and self-efficacy, respectively. SETTING: One WIC clinic in central Illinois. PARTICIPANTS: First-time BF African American mothers enrolled in WIC (n = 15)...
July 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28688999/assessing-the-implementation-of-a-bedside-service-handoff-on-an-academic-hospitalist-service
#10
Charlie M Wray, Vineet M Arora, Donald Hedeker, David O Meltzer
BACKGROUND: Inpatient service handoffs are a vulnerable transition during a patients' hospitalization. We hypothesized that performing the service handoff at the patients' bedside may be one mechanism to more efficiently transfer patient information between physicians, while further integrating the patient into their hospital care. METHODS: We performed a 6-month prospective study of performing a bedside handoff (BHO) at the service transition on a non-teaching hospitalist service...
July 5, 2017: Healthcare
https://www.readbyqxmd.com/read/28687740/organization-and-hierarchy-of-the-human-functional-brain-network-lead-to-a-chain-like-core
#11
Rossana Mastrandrea, Andrea Gabrielli, Fabrizio Piras, Gianfranco Spalletta, Guido Caldarelli, Tommaso Gili
The brain is a paradigmatic example of a complex system: its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in terms of links (correlations) between nodes (grey matter regions) and to extract information out of the noise. Here we present the analysis of functional magnetic resonance imaging data from forty healthy humans at rest for the investigation of the basal scaffold of the functional brain network organization...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28683927/cognitive-control-during-a-spatial-stroop-task-comparing-conflict-monitoring-and-prediction-of-response-outcome-theories
#12
Luís Pires, José Leitão, Chiara Guerrini, Mário R Simões
Cognitive control allows information processing and behaviour to vary adaptively from moment to moment depending on current goals. Two of the most prominent theories that have been proposed to account for the processing of cognitive control are the Conflict Monitoring Theory (CMT) and the Prediction of Response-Outcome Theory (PRO). According to both theories, the implementation of cognitive control during a trial in a conflict task reflects processing events that occurred in the preceding trial. Both CMT and PRO advocate that the detection of conflict situations leads to the recruitment of cognitive control, but they differ regarding the processing underpinnings of cognitive control during conflict resolution...
July 3, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28681879/exploring-the-chemical-kinetics-of-partially-oxidized-intermediates-by-combining-experiments-theory-and-kinetic-modeling
#13
Karlheinz Hoyermann, Fabian Mauß, Matthias Olzmann, Oliver Welz, Thomas Zeuch
Partially oxidized intermediates play a central role in combustion and atmospheric chemistry. In this perspective, we focus on the chemical kinetics of alkoxy radicals, peroxy radicals, and Criegee intermediates, which are key species in both combustion and atmospheric environments. These reactive intermediates feature a broad spectrum of chemical diversity. Their reactivity is central to our understanding of how volatile organic compounds are degraded in the atmosphere and converted into secondary organic aerosol...
July 6, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28678104/exploring-faculty-developers-experiences-to-inform-our-understanding-of-competence-in-faculty-development
#14
Lindsay Baker, Karen Leslie, Danny Panisko, Allyn Walsh, Anne Wong, Barbara Stubbs, Maria Mylopoulos
PURPOSE: Now a mainstay in medical education, faculty development has created the role of the faculty developer. However, faculty development research tends to overlook faculty developers' roles and experiences. This study aimed to develop an empirical understanding of faculty developer competence by digging deeper into the actions, experiences, and perceptions of faculty developers as they perform their facilitator role. METHOD: A constructivist grounded theory approach guided observations of faculty development activities, field interviews, and formal interviews with 31 faculty developers across two academic institutions from 2013 to 2014...
July 3, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28670503/aware-motivated-and-striving-for-a-safe-tan-an-exploratory-mixed-method-study-of-sun-protection-during-holidays
#15
Angela M Rodrigues, Falko F Sniehotta, Mark A Birch-Machin, Vera Araujo-Soares
Background: This article presents an exploratory study, aiming to explore the correspondence between knowledge, motivation and sun-protection practices during holidays. Methods: Seventeen participants aged 21-62 years old, recruited from community settings took part in individual face-to-face semi-structured interviews, completed sun sensitivity questions and an objective assessment of sunscreen use. Holidaymakers' knowledge about sun-safe messages, intentions and perceptions of barriers and facilitators for sun-protection were assessed...
2017: Health Psychology and Behavioral Medicine
https://www.readbyqxmd.com/read/28649583/effects-of-alcohol-on-human-aggression
#16
Dominic J Parrott, Christopher I Eckhardt
There is little debate that alcohol is a contributing cause of aggressive behavior. The extreme complexity of this relation, however, has been the focus of extensive theory and research. And, likely due to this complexity, evidence-based programs to prevent or reduce alcohol-facilitated aggression are quite limited. We integrate I(3) Theory and Alcohol Myopia Theory to provide a framework that (1) organizes the myriad instigatory and inhibitory factors that moderate the effect of alcohol on aggression, and (2) highlights the mechanisms by which alcohol facilitates aggression among at-risk individuals...
February 2018: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28648696/integrating-behaviour-into-the-pace-of-life-continuum-divergent-levels-of-activity-and-information-gathering-in-fast-and-slow-living-snakes
#17
Eric J Gangloff, Melinda Chow, Vianey Leos-Barajas, Stephanie Hynes, Brooke Hobbs, Amanda M Sparkman
An animal's life history, physiology, and behaviour can be shaped by selection in a manner that favours strong associations among these aspects of an integrated phenotype. Recent work combining animal personality and life-history theory proposes that animals with faster life-history strategies (i.e., fast growth, high annual reproductive rate, short lifespan) should exhibit higher general activity levels relative to those with slower life-history strategies, but empirical tests of within-species variation in these traits are lacking...
June 22, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28646851/development-of-an-education-campaign-to-reduce-delays-in-pre-hospital-response-to-stroke
#18
Caterina Caminiti, Peter Schulz, Barbara Marcomini, Elisa Iezzi, Silvia Riva, Umberto Scoditti, Andrea Zini, Giovanni Malferrari, Maria Luisa Zedde, Donata Guidetti, Enrico Montanari, Mario Baratti, Licia Denti
BACKGROUND: Systematic reviews call for well-designed trials with clearly described intervention components to support the effectiveness of educational campaigns to reduce patient delay in stroke presentation. We herein describe the systematic development process of a campaign aimed to increase stroke awareness and preparedness. METHODS: Campaign development followed Intervention Mapping (IM), a theory- and evidence-based tool, and was articulated in two phases: needs assessment and intervention development...
June 24, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28643559/informing-healthcare-waiting-area-design-using-transparency-attributes-a-comparative-preference-study
#19
Shan Jiang, Matthew Powers, David Allison, Ellen Vincent
OBJECTIVE: This study aimed to explore people's visual preference for waiting areas in general hospital environments designed with transparency attributes that fully integrate nature. BACKGROUND: Waiting can be a tedious and frustrating experience among people seeking healthcare treatments and negatively affect their perception of the quality of care. Positive distractions and supportive designs have gained increasing attraction to improve people's waiting experience...
July 2017: HERD
https://www.readbyqxmd.com/read/28641817/-preventing-violence-in-schizophrenia-with-cognitive-remediation
#20
C Darmedru, C Demily, N Franck
OBJECTIVES: The association between schizophrenia and violence represents an important issue in psychiatry. Often highly publicized, violent acts raise the question of their detection, prevention, management and treatment. There is no single, direct and exclusive link between aggressiveness and the underlying psychiatric disorder. On the contrary, the processes underlying this violence are multiple and interlinked. In addition to static and dynamic risk factors, cognitive deficits play an important role in the genesis and maintenance of violent and aggressive behavior...
June 19, 2017: L'Encéphale
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