keyword
MENU ▼
Read by QxMD icon Read
search

Complementary

keyword
https://www.readbyqxmd.com/read/29031213/impairment-of-heart-rhythm-complexity-in-patients-with-drug-resistant-epilepsy-an-assessment-with-multiscale-entropy-analysis
#1
Hongyun Liu, Zhao Yang, Fangang Meng, Yuguang Guan, Yanshan Ma, Shuli Liang, Jiuluan Lin, Longsheng Pan, Mingming Zhao, Wei Qu, Hongwei Hao, Guoming Luan, Jianguo Zhang, Luming Li
OBJECTIVE: Epilepsy and seizures can have dramatic effects on the cardiac function. The aim of this study was to investigate the heart rhythm complexity in patients with drug-resistant epilepsy (DRE). METHODS: Ambulatory 24-h electrocardiograms (ECG) from 70 DRE patients and 50 healthy control subjects were analyzed using conventional heart rate variability (HRV) and multiscale entropy (MSE) methods The variation of complexity indices (CI), which was calculated from MSE profile, was determined...
October 5, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29029282/ecoinformatics-can-infer-causal-effects-of-crop-variety-on-insect-attack-by-capitalizing-on-pseudoexperiments-created-when-different-crop-varieties-are-interspersed-a-case-study-in-almonds
#2
Jay A Rosenheim, Bradley S Higbee, Jonathan D Ackerman, Matthew H Meisner
Capturing the complementary strengths of observational and experimental research methods usually requires the researcher to gather separate experimental and observational data sets. In some cases, however, commercial agricultural practices produce the spatial and temporal mixing of 'treatments' independently of other possibly covarying factors that is normally achieved only with formal experimentation. The resulting 'pseudoexperiments' can provide strong evidence for causal relationships. Here, we analyze a large observational data set that creates a series of such pseudoexperiments to assess the effect of different commercial varieties of almond, Prunus dulcis (Mill...
September 27, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29028923/detecting-presence-of-mutational-signatures-in-cancer-with-confidence
#3
Xiaoqing Huang, Damian Wojtowicz, Teresa M Przytycka
Motivation: Cancers arise as the result of somatically acquired changes in the DNA of cancer cells. However, in addition to the mutations that confer a growth advantage, cancer genomes accumulate a large number of somatic mutations resulting from normal DNA damage and repair processes as well as carcinogenic exposures or cancer related aberrations of DNA maintenance machinery. These mutagenic processes often produce characteristic mutational patterns called mutational signatures. The decomposition of a cancer genome's mutation catalog into mutations consistent with such signatures can provide valuable information about cancer etiology...
September 22, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29028779/an-investigation-of-the-use-of-traditional-chinese-medicine-and-complementary-and-alternative-medicine-in-stroke-patients
#4
Mei-Ling Yeh, Wei-Ling Chiu, Yu-Jen Wang, Chyi Lo
This study aimed to investigate the use of traditional Chinese medicine and complementary and alternative medicine in stroke patients in Taiwan. Chinese herbal medicine, massage, acupuncture, natural products, and exercise were widely used among stroke patients. Integrating safe and effective traditional Chinese medicine and complementary and alternative medicine into conventional therapies is suggested.
November 2017: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29028603/a-surface-confined-dna-assembly-amplification-strategy-on-dna-nanostructural-scaffold-for-electrochemiluminescence-biosensing
#5
Qiu-Mei Feng, Yue-Hua Guo, Jing-Juan Xu, Hong-Yuan Chen
A critical challenge in surface-based DNA assembly amplification is the reduced accessibility of DNA strands arranged on a heterogeneous surface compared to that in homogeneous solution. Here, a novel in situ surface-confined DNA assembly amplification electrochemiluminescence (ECL) biosensor based on DNA nanostructural scaffold was presented. In this design, a stem-loop structural DNA segment (Hairpin 1) was constructed on the vertex of DNA nanostructural scaffold as recognition probe. In the present of target DNA, the hairpin structure changed to rod-like through complementary hybridization with target DNA, resulting in the formation of Hairpin 1:target DNA...
September 22, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29028465/cultivating-humility-and-diagnostic-openness-in-clinical-judgment
#6
John R Stone
In this case, a physician rejects a patient's concerns that tainted water is harming the patient and her community. Stereotypes and biases regarding socioeconomic class and race/ethnicity, constraining diagnostic frameworks, and fixed first impressions could skew the physician's judgment. This paper narratively illustrates how cultivating humility could help the physician truly hear the patient's suggestions. The discussion builds on the multifaceted concept of cultural humility as a lifelong journey that addresses not only stereotypes and biases but also power inequalities and community inequities...
October 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29028397/detection-of-gas-traces-using-semiconductor-sensors-ion-mobility-spectrometry-and-mass-spectrometry
#7
Yulia R Shaltaeva, Boris I Podlepetsky, Vyacheslav S Pershenkov
This article deals with the state-of-the-art instrumentation and application in the field of solid state gas sensorics, ion mobility spectrometry and mass-spectrometry-related research for the detection and measurements of low gas and vapor concentrations. The advantages and disadvantages of gas-analytical devices and systems are discussed, as well as the possibilities of its complex and/or complementary applications. Ion mobility spectrometry-mass spectrometry and subsequent techniques based on solid-state gas sensors are proposed for planned medical study...
August 2017: European Journal of Mass Spectrometry
https://www.readbyqxmd.com/read/29028334/dynamic-control-of-aptamer-ligand-activity-using-strand-displacement-reactions
#8
Jonathan Lloyd, Claire H Tran, Krishen Wadhwani, Christian Cuba Samaniego, Hari K K Subramanian, Elisa Franco
Nucleic acid aptamers are an expandable toolkit of sensors and regulators. To employ aptamer regulators within non-equilibrium molecular networks, the aptamer-ligand interactions should be tunable over time, so that functions within a given system can be activated or suppressed on demand. This is accomplished through complementary sequences to aptamers, which achieve programmable aptamer-ligand dissociation by displacing the aptamer from the ligand. We demonstrate the effectiveness of our simple approach on light-up aptamers as well as on aptamers inhibiting viral RNA polymerases, dynamically controlling the functionality of the aptamer-ligand complex...
October 13, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/29028298/ultrathin-nanocrystalline-diamond-films-with-silicon-vacancy-color-centers-via-seeding-by-2-nm-detonation-nanodiamonds
#9
Stepan Stehlik, Marian Varga, Pavla Štenclová, Lukáš Ondič, Martin Ledinsky, Jiří Pangrác, Ondrej Vanek, Jan Lipov, Alexander Kromka, Bohuslav Rezek
Color centers in diamond have shown excellent potential for applications in quantum information processing, photonics, and biology. Here we report chemical vapor deposition (CVD) growth of as thin as 5-6 nm nanocrystalline diamond (NCD) films with photoluminescence (PL) from silicon-vacancy (SiV) centers at 739 nm. Instead of conventional 4-6 nm detonation nanodiamonds (DNDs) we prepared and employed hydrogenated 2 nm DNDs (zeta potential +36 mV) to form extremely dense (~ 1.3 × 1013 cm-2), thin (2 ± 1 nm) and smooth (RMS roughness < 0...
October 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29027931/discovering-the-biological-target-of-5-epi-sinuleptolide-using-a-combination-of-proteomic-approaches
#10
Elva Morretta, Roberta Esposito, Carmen Festa, Raffaele Riccio, Agostino Casapullo, Maria Chiara Monti
Sinuleptolide and its congeners are diterpenes with a norcembranoid skeleton isolated from the soft coral genus Sinularia. These marine metabolites are endowed with relevant biological activities, mainly associated with cancer development. 5-epi-sinuleptolide has been selected as a candidate for target discovery studies through the application of complementary proteomic approaches. Specifically, a combination of conventional chemical proteomics based on affinity chromatography, coupled with high-resolution mass spectrometry and bioinformatics, as well as drug affinity responsive target stability (DARTS), led to a clear identification of actins as main targets for 5-epi-sinuleptolide...
October 13, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29027921/binding-direction-based-two-dimensional-flattened-contact-area-computing-algorithm-for-protein-protein-interactions
#11
Beom Sik Kang, GaneshKumar Pugalendhi, Ku-Jin Kim
Interactions between protein molecules are essential for the assembly, function, and regulation of proteins. The contact region between two protein molecules in a protein complex is usually complementary in shape for both molecules and the area of the contact region can be used to estimate the binding strength between two molecules. Although the area is a value calculated from the three-dimensional surface, it cannot represent the three-dimensional shape of the surface. Therefore, we propose an original concept of two-dimensional contact area which provides further information such as the ruggedness of the contact region...
October 13, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29027863/potential-utility-of-flair-in-mri-negative-cushing-s-disease
#12
Grégoire P Chatain, Nicholas Patronas, James G Smirniotopoulos, Martin Piazza, Sarah Benzo, Abhik Ray-Chaudhury, Susmeeta Sharma, Maya Lodish, Lynnette Nieman, Constantine A Stratakis, Prashant Chittiboina
OBJECTIVE Accurate presurgical localization of microadenomas in Cushing's disease (CD) leads to improved remission rates and decreased adverse events. Volumetric gradient recalled echo (3D-GRE) MRI detects pituitary microadenomas in CD in up to 50%-80% cases as a focus of hypointensity due to delayed contrast wash-in. The authors have previously reported that postcontrast FLAIR imaging may be useful in detecting otherwise MRI-negative pituitary microadenomas as foci of hyperintensity. This reflects theoretically complementary imaging of microadenomas due to delayed contrast washout...
October 13, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29027787/detection-of-t4-polynucleotide-kinase-via-allosteric-aptamer-probe-platform
#13
Mingxuan Gao, Jingjing Guo, Yanling Song, Zhi Zhu, Chaoyong James Yang
As a vital enzyme in DNA phosphorylation and restoration, T4 polynuceotide kinase (T4 PNK) has aroused great interest in recent years. Numerous strategies have been established for highly sensitive detection of T4 PNK based on diverse signal amplification techniques. However, they often need sophisticated design, a variety of auxiliary reagents and enzymes, or cumbersome manipulations. Herein, we have designed a new kind of allosteric aptamer probe consisting of streptavidin aptamer (SA aptamer) and the complementary DNA (cDNA) for simple detection of T4 PNK without signal amplification and with minimized interference in complex biological samples...
October 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29027752/label-free-multiplex-dna-detection-utilizing-projected-capacitive-touchscreen
#14
Joon Young Lee, Byoung Yeon Won, Hyun Gyu Park
We have developed a novel strategy to achieve label-free multiplex DNA detection system based on the projected capacitive touchscreen. Touchscreen panel was first fabricated by patterning the ITO (indium-tin-oxide) electrode array on the glass wafer, and the electrodes were modified with the respective capture probe DNA sequences complementary to hemagglutinin1 (H1), neuraminidase1 (N1), and matrix1 (M1) DNA to demonstrate the molecular diagnosis of H1N1 influenza virus as a model pathogen. DNA sample was then applied to the electrodes to allow hybridization of target DNA with the corresponding complementary capture probe...
October 13, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#15
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29027330/poor-nutrition-from-first-foods-a-cross-sectional-study-of-complementary-feeding-of-infants-and-young-children-in-six-remote-aboriginal-communities-across-northern-australia
#16
Dympna Leonard, Danielle Aquino, Nyssa Hadgraft, Fintan Thompson, Julia V Marley
AIM: To describe the first foods of Aboriginal and Torres Strait Islander infants and young children who were recruited to a nutrition promotion and anaemia prevention program conducted from 2010 to 2012, in six remote communities across northern Australia. METHODS: Food records (24-hour diet history, food variety checklist) were completed on recruitment by interview with a parent or carer. Cross-sectional analysis assessed the proportion of participants consuming recommended and not-recommended foods and drinks and meeting recommendations for meal frequency and dietary diversity...
October 13, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29027117/immature-platelet-fraction-ipf-as-a-predictive-value-for-thrombopoietic-recovery-after-allogeneic-stem-cell-transplantation
#17
Mikiko Sakuragi, Satoru Hayashi, Miho Maruyama, Tomoko Kiyokawa, Keisuke Nagamine, Jiro Fujita, Tetsuo Maeda, Hisashi Kato, Hirokazu Kashiwagi, Yuzuru Kanakura, Yoshiaki Tomiyama
We consecutively examined the utility of measurements of percentage of immature platelet fraction (IPF%) and absolute IPF number (A-IPF) in predicting thrombopoietic recovery in 15 adult patients who underwent allogeneic hematopoietic stem cell transplantation (allo-SCT). Four patients were excluded from the evaluation due to insufficient data. Platelet count and IPF were measured by Sysmex XN-1000 (XN), a newer generation analyzer. First, we confirmed that platelet count measured by XN was more accurate than by XE-2100 (XE)...
October 12, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/29027089/a-decade-of-a-thrips-invasion-in-china-lessons-learned
#18
Shengyong Wu, Liangde Tang, Xingrui Zhang, Zhenlong Xing, Zhongren Lei, Yulin Gao
The Western flower thrips, Frankliniella occidentalis Pergande (Thysanoptera: Thripidae) is an invasive polyphagous pest with an expanding global range that damages a wide variety of crops. F. occidentalis was first reported in China from Yunnan province during 2000, and has rapidly expanded its range since then. It is currently distributed across at least 10 provinces in China and has become a particularly devastating pest, causing substantial damage and economic losses. At present, the still heavy reliance on frequent use of insecticides for control of F...
October 11, 2017: Ecotoxicology
https://www.readbyqxmd.com/read/29027087/the-effect-of-using-a-dielectric-matching-medium-in-focused-microwave-radiometry-an-anatomically-detailed-head-model-study
#19
Maria Koutsoupidou, Evangelos Groumpas, Irene S Karanasiou, Maria Christopoulou, Konstantina Nikita, Nikolaos Uzunoglu
Microwave radiometry is a passive technique used to measure in-depth temperature distributions inside the human body, potentially useful in clinical applications. Experimental data imply that it may provide the capability of detecting in-depth local variations of temperature and/or conductivity of excitable tissues at microwave frequencies. Specifically, microwave radiometry may allow the real-time monitoring of brain temperature and/or conductivity changes, associated with local brain activation. In this paper, recent results of our ongoing research regarding the capabilities of focused microwave radiometry for brain intracranial applications are presented...
October 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29026998/acetolactate-synthase-alss-in-bacillus-licheniformis-wx-02-enzymatic-properties-and-efficient-functions-for-acetoin-butanediol-and-l-valine-biosynthesis
#20
Yanli Huo, Yangyang Zhan, Qin Wang, Shunyi Li, Shihui Yang, Christopher T Nomura, Changjun Wang, Shouwen Chen
Acetolactate synthase catalyzes two molecules of pyruvates to form α-acetolactate, which is further converted to acetoin and 2,3-butanediol. In this study, by heterologous expression in Escherichia coli, the enzymatic properties of acetolactate synthase (AlsS) from Bacillus licheniformis WX-02 were characterized. Its K m and k cat for pyruvate were 3.96 mM and 514/s, respectively. It has the optimal activity at pH 6.5, 37 °C and was feedback inhibited by L-valine, L-leucine and L-isoleucine. Furthermore, the alsS-deficient strain could not produce acetoin, 2,3-butanediol, and L-valine, while the complementary strain was able to restore these capacities...
October 11, 2017: Bioprocess and Biosystems Engineering
keyword
keyword
2381
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"