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https://www.readbyqxmd.com/read/28931244/the-importance-of-frailty-in-the-assessment-of-influenza-vaccine-effectiveness-against-influenza-related-hospitalization-in-elderly-people
#1
Melissa K Andrew, Vivek Shinde, Lingyun Ye, Todd Hatchette, François Haguinet, Gael Dos Santos, Janet E McElhaney, Ardith Ambrose, Guy Boivin, William Bowie, Ayman Chit, May ElSherif, Karen Green, Scott Halperin, Barbara Ibarguchi, Jennie Johnstone, Kevin Katz, Joanne Langley, Jason Leblanc, Mark Loeb, Donna MacKinnon-Cameron, Anne McCarthy, Allison McGeer, Jeff Powis, David Richardson, Makeda Semret, Grant Stiver, Sylvie Trottier, Louis Valiquette, Duncan Webster, Shelly A McNeil
Background: Influenza is an important cause of morbidity and mortality among older adults. Even so, effectiveness of influenza vaccine for older adults has been reported to be lower than for younger adults, and the impact of frailty on vaccine effectiveness (VE) and outcomes is uncertain. We aimed to study VE against influenza hospitalization in older adults, focusing on the impact of frailty. Methods: We report VE of trivalent influenza vaccine (TIV) in people ≥65 years of age hospitalized during the 2011-2012 influenza season using a multicenter, prospective, test-negative case-control design...
August 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28931027/characteristics-of-informal-caregivers-who-provide-transportation-assistance-to-older-adults
#2
David W Eby, Lisa J Molnar, Lidia P Kostyniuk, Renée M St Louis, Nicole Zanier
The study aim was to gain a better understanding of the characteristics of informal caregivers who provide transportation assistance and to explore the types and frequency of this assistance. A telephone survey was administered to a representative sample of 268 informal caregivers (age 45-80) who provide transportation assistance to older adults (age 70 and older) in Michigan. Responses were analyzed overall and by the caregiver sex and care recipient age. Informal transportation caregivers were: most often women; on average 61 years old; generally college educated; employed full- or part-time jobs; relatively healthy; providing care to a parent/family member 1-4 times per week, living close to the care recipient; and providing assistance by giving rides...
2017: PloS One
https://www.readbyqxmd.com/read/28929999/effects-of-cognitive-training-on-cognitive-performance-of-healthy-older-adults
#3
Mariana Teles Santos Golino, Carmen Flores Mendoza, Hudson Fernandes Golino
The purpose of this study was to determine the immediate effects of cognitive training on healthy older adults and verify the transfer effects of targeted and non-targeted abilities. The design consisted of a semi-randomized clinical controlled trial. The final sample was composed of 80 volunteers recruited from a Brazilian community (mean age = 69.69; SD = 7.44), which were separated into an intervention group (N = 47; mean age = 69.66, SD = 7.51) and a control group (N = 33; mean age = 69.73, SD = 7.45). Intervention was characterized by adaptive cognitive training with 12 individual training sessions of 60 to 90 minutes (once a week)...
September 20, 2017: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/28929520/a-short-report-on-tooth-replacement-in-an-older-suburban-population-in-nigeria
#4
Olushola Ibiyemi, Folake B Lawal
OBJECTIVES: To determine: the knowledge of the participants about removable dentures, importance of tooth replacement; prevalence of tooth loss and denture use; and factors associated with its non-use among an elderly population in Nigeria. BACKGROUND: Tooth loss without replacement can impact negatively on the quality of life of the elders, thus making use of denture a basic requirement for those with partial or complete edentulous arches in developed countries...
September 20, 2017: Gerodontology
https://www.readbyqxmd.com/read/28927581/differential-aging-signals-in-abdominal-ct-scans
#5
Nikita V Orlov, Sokratis Makrogiannis, Luigi Ferrucci, Ilya G Goldberg
RATIONALE AND OBJECTIVES: Changes in the composition of body tissues are major aging phenotypes, but they have been difficult to study in depth. Here we describe age-related change in abdominal tissues observable in computed tomography (CT) scans. We used pattern recognition and machine learning to detect and quantify these changes in a model-agnostic fashion. MATERIALS AND METHODS: CT scans of abdominal L4 sections were obtained from Baltimore Longitudinal Study of Aging (BLSA) participants...
September 15, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28926363/blood-pressure-measurements-over-thin-and-thick-sleeves-in-the-frail-elderly
#6
Sachiko Ozone, Mikiya Sato, Ayumi Takayashiki, Takuya Sato, Aya Matsushita, Hisashi Yoshimoto, Tetsuhiro Maeno
OBJECTIVE: Blood pressure (BP) measurement is recommended on bare arms, but undressing the arms for BP measurements is often difficult for frail elderly individuals. We aimed to assess the accuracy of BP measurements over arms with thin and thick clothing among the frail elderly. PARTICIPANTS AND METHODS: This is a cross-sectional study. Individuals aged 65 years or older were recruited from three long-term care facilities in Japan between April and May 2016. The main outcome measures were BP measurements (a) on a bare arm, (b) over a thin shirt, (c) over a thin shirt and a cardigan, and (d) over the sleeve of a thin shirt and a cardigan rolled up to the elbow...
September 18, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28926326/prevalence-of-hepatitis-a-virus-antibody-in-portuguese-travelers-a-new-paradigm
#7
Sónia Rocha, Sandra Tejo, Eugénia Ferreira, Luís Trindade, Eduardo Rabadão, Nuno Marques, José Saraiva da Cunha
INTRODUCTION: In Portugal, the prevalence of hepatitis A virus infection has decreased in the past decades, especially in young adults. The aim of this study was to detect the prevalence of antibody to hepatitis A virus in a population observed in our Travel Clinic. MATERIAL AND METHODS: Antibodies against hepatitis A, hepatitis B, hepatitis C and human immunodeficiency virus were tested using standard enzyme immunoassay in patients older than 18. The exclusion criteria were: prior vaccination for hepatitis A virus, previous diagnosis of infection with hepatitis B virus, hepatitis C virus and/or human immunodeficiency virus, foreign travelers and long-term expatriates...
August 31, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28926125/the-prevalence-of-vertebral-fractures-is-associated-with-reduced-hip-bone-density-and-inferior-peripheral-appendicular-volumetric-bone-density-and-structure-in-older-women
#8
Lisa Johansson, Daniel Sundh, Michael Zoulakis, Robert Rudäng, Anna Darelid, Helena Brisby, Anna G Nilsson, Dan Mellström, Mattias Lorentzon
Vertebral fractures (VF) are among the most severe and prevalent osteoporotic fractures. Their association with bone microstructure have been investigated in several retrospective case-control studies with spine radiography for diagnosis of VF. The aim of this population-based cross-sectional study of 1027 women aged 75-80 years, was to investigate if prevalent VF, identified by vertebral fracture assessment (VFA) by dual-energy X-ray absorptiometry (DXA), was associated with appendicular volumetric bone density, structure and bone material strength index (BMSi), independently of hip areal bone mineral density (aBMD)...
September 19, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28923181/centenarians-in-europe
#9
Laetitia Teixeira, Lia Araújo, Daniela Jopp, Oscar Ribeiro
OBJECTIVES: The group of individuals aged 80 and over is growing faster than other segments of the population, and within this group the number of centenarians has risen exponentially worldwide. This paper reports the numbers of centenarians (total, and ratio relative to total population) in 32 European countries and their key characteristics: gender distribution, level of education, and type of residence. STUDY DESIGN: Population based study. MEASURES: We used national census data collected in 2011 for individuals aged 100 and over living in Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland and the UK...
October 2017: Maturitas
https://www.readbyqxmd.com/read/28921721/effects-of-the-availability-of-accurate-proprioceptive-information-on-older-adults-postural-sway-and-muscle-co-contraction
#10
Chesney E Craig, Glenn H M Calvert, Michail Doumas
During conditions of increased postural instability, older adults exhibit greater lower-limb muscle co-contraction. This response has been interpreted as a compensatory postural strategy, which may be used to i006Ecrease proprioceptive information from muscle spindles or to stiffen the lower limb as a general response to minimise postural sway. The current study aimed to test these two hypotheses by investigating use of muscle co-contraction during sensory transitions that manipulated proprioceptive input. Surface EMG was recorded from the bilateral tibialis anterior and gastrocnemius medialis muscles, in young (aged 18-30) and older adults (aged 68-80) during blind-folded postural assessment...
September 16, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28921036/long-term-outcomes-and-predictors-of-failure-after-surgery-for-stage-iv-apical-pelvic-organ-prolapse
#11
Brian J Linder, Sherif A El-Nashar, Alain A Mukwege, Amy L Weaver, Michaela E McGree, Deborah J Rhodes, John B Gebhart, Christopher J Klingele, John A Occhino, Emanuel C Trabuco
INTRODUCTION AND HYPOTHESIS: The aim of this study was to compare outcomes after uterosacral ligament suspension (USLS) or sacrocolpopexy for symptomatic stage IV apical pelvic organ prolapse (POP) and evaluate predictors of prolapse recurrence. METHODS: The medical records of patients managed surgically for stage IV apical POP from January 2002 to June 2012 were reviewed. A follow-up survey was sent to these patients. The primary outcome, prolapse recurrence, was defined as recurrence of prolapse symptoms measured by validated questionnaire or surgical retreatment...
September 18, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28919313/periprocedural-outcomes-of-carotid-artery-stenting-in-elderly-patients
#12
Masataka Nanto, Yudai Goto, Hiroyuki Yamamoto, Seisuke Tanigawa, Michiko Takado, Takahiro Ogawa, Yoshikazu Nakahara
BACKGROUND: Carotid artery stenting has emerged as an alternative to carotid endarterectomy especially in patients with high risk of carotid endarterectomy. Older age (≥80 years old) was recognized as one of the high risk factors of carotid endarterectomy. However, the association between older age and increased risk of adverse events for carotid artery stenting has been reported. The purpose of this study was to evaluate the association between age and periprocedural outcomes after carotid artery stenting...
September 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28919116/global-regional-and-national-age-sex-specific-mortality-for-264-causes-of-death-1980-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#13
(no author information available yet)
BACKGROUND: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluation of the expected epidemiological transition with changes in development and where local patterns deviate from these trends. METHODS: We estimated cause-specific deaths and years of life lost (YLLs) by age, sex, geography, and year...
September 16, 2017: Lancet
https://www.readbyqxmd.com/read/28918171/the-association-between-delirium-and-sarcopenia-in-older-adult-patients-admitted-to-acute-geriatrics-units-results-from-the-glisten-multicenter-observational-study
#14
Giuseppe Bellelli, Antonella Zambon, Stefano Volpato, Pasquale Abete, Lara Bianchi, Mario Bo, Antonio Cherubini, Francesco Corica, Mauro Di Bari, Marcello Maggio, Giovanna Maria Manca, Maria Rosaria Rizzo, Andrea Rossi, Francesco Landi
BACKGROUND & AIMS: To date, studies assessing the relationship between sarcopenia and delirium, two of the most common geriatric syndromes, are lacking. We sought to explore this association by investigating the co-occurrence of these two conditions and the independent association between them in a population of hospitalized older adults. METHODS: Cross-sectional multicenter analysis of older adults consecutively admitted to 12 acute geriatric units (AGUs). Sarcopenia was assessed upon admission by evaluating the presence of low skeletal mass index (kg/m(2)), and either low handgrip strength or low walking speed (European Working Group on Sarcopenia in Older People, EWGSOP criteria)...
September 5, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28916571/effect-of-soy-and-soy-isoflavones-on-obesity-related-anthropometric-measures-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#15
REVIEW
Masoumeh Akhlaghi, Morteza Zare, Fatemeh Nouripour
Soy may be a suitable food for anti-obesity efforts because of its high protein and isoflavone content. We conducted this meta-analysis to evaluate potential effects of soy and soy isoflavones on weight, waist circumference, and fat mass. PubMed, MEDLINE, Scopus, EMBASE, and Cochrane databases were searched. Twenty-four trials with soy and 17 trials with isoflavones passed the eligibility stage. According to the results, soy showed no overall statistically significant effect on weight, waist circumference, or fat mass, but a significant increasing effect on weight was observed in some circumstances: for instance, in obese subjects [mean difference (MD): 0...
September 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28914998/clinicopathological-characteristics-of-distant-metastases-of-adenocarcinoma-squamous-cell-carcinoma-and-urothelial-carcinoma-an-autopsy-study-of-older-japanese-patients
#16
Yoko Matsuda, Atsuko Seki, Keisuke Nonaka, Mototsune Kakizaki, Tan Wang, Junko Aida, Naoshi Ishikawa, Yuta Nakano, Daita Kaneda, Tadayuki Takata, Junko Takahashi-Fujigasaki, Shigeo Murayama, Kaiyo Takubo, Toshiyuki Ishiwata, Motoji Sawabe, Tomio Arai
AIM: We aimed to clarify the characteristics of malignancies in older adults focusing on distant metastasis in the whole body. METHODS: We retrospectively evaluated 7710 cases of autopsies (4011 men, 3699 women, median age of 80 years), and analyzed the characteristics of metastasis of adenocarcinoma, squamous cell carcinoma and urothelial carcinoma in each organ. RESULTS: The total number of cases with adenocarcinoma, squamous cell carcinoma or urothelial carcinoma was 2856, and most of them were adenocarcinomas...
September 15, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28914959/nocturia-is-associated-with-poor-sleep-quality-among-older-women-in-the-study-of-osteoporotic-fractures
#17
Constance H Fung, Camille P Vaughan, Alayne D Markland, Alison J Huang, Michael N Mitchell, Donald L Bliwise, Sonia Ancoli-Israel, Susan Redline, Cathy A Alessi, Katie Stone
OBJECTIVES: (1) To examine relationships between frequency of nocturia and self-reported sleep quality and objective sleep measures in older women, and (2) to estimate the amount of variation in sleep measures that is specifically attributable to frequency of nocturia. DESIGN AND SETTING: Secondary, cross sectional analysis of the multicenter prospective cohort Study of Osteoporotic Fractures (SOF). PARTICIPANTS: Community-dwelling women aged ≥80 years...
September 15, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28914724/the-role-of-brain-structure-in-predicting-adherence-to-a-physical-activity-regimen
#18
Swathi Gujral, Edward McAuley, Lauren E Oberlin, Arthur F Kramer, Kirk I Erickson
OBJECTIVE: Physical activity is important for maintaining health throughout the lifespan. However, adherence to PA regimens is poor with approximately 50% of older adults terminating activity intervention programs within 6 months. In this study we tested whether gray matter volume and white matter microstructural integrity prior to the initiation of a PA intervention predicts PA adherence. METHODS: 159 adults aged 60-80 years were randomly assigned to a moderate-intensity aerobic walking condition or a non-aerobic stretching and toning condition...
September 13, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28914585/planning-future-care-services-analyses-of-investments-in-norwegian-municipalities
#19
Terje P Hagen, Laila Tingvold
AIMS: To analyse whether the Norwegian Central Government's goal of subsidizing 12,000 places in nursing homes or sheltered housing using an earmarked grant was reached and to determine towards which group of users the planned investments were targeted. METHODS: Data from the investment plans at municipal level were provided by the Norwegian Housing Bank and linked to variables describing the municipalities' financial situation as well as variables describing the local needs for services provided by Statistics Norway...
September 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28914446/risk-factors-for-thiopurine-induced-myelosuppression-and-infections-in-inflammatory-bowel-disease-patients-with-a-normal-tpmt-genotype
#20
M M T J Broekman, M J H Coenen, G J Wanten, C J van Marrewijk, O H Klungel, A L M Verbeek, P M Hooymans, H-J Guchelaar, H Scheffer, L J J Derijks, D R Wong, D J de Jong
BACKGROUND: Leucopenia is a common side effect in patients treated with thiopurines. Variants in the thiopurine S-methyltransferase (TPMT) gene are the best-known risk factor, but only explain up to 25% of leucopenia cases. AIM: To identify the clinical risk factors for thiopurine-induced leucopenia in patients without a common TPMT variant, and explore if these patients are at increased risk for infections. METHODS: Post hoc analysis of the Thiopurine response Optimisation by Pharmacogenetic testing in Inflammatory bowel disease Clinics (TOPIC) trial...
September 15, 2017: Alimentary Pharmacology & Therapeutics
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