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https://www.readbyqxmd.com/read/28742717/integrating-an-interprofessional-education-experience-into-a-human-physiology-course
#1
Scott Edwards, Patricia E Molina, Kathleen H McDonough, Donald E Mercante, Tina P Gunaldo
PURPOSE: To obtain physician assistant (PA) student perceptions about an interprofessional education (IPE) training experience embedded in a multidisciplinary science course. METHODS: An IPE training experience was integrated into a graduate human physiology course offered to PA, physical therapy, and graduate studies students. The focus of the activity related to the Interprofessional Education Collaborative (IPEC) competency domains of (1) roles and responsibilities and (2) teams and teamwork...
July 20, 2017: Journal of Physician Assistant Education
https://www.readbyqxmd.com/read/28742479/understanding-and-combating-resistance-to-online-learning
#2
John Vivolo
Resistance to change is an easy thing for human beings to understand. It is at the heart of our desire to find comfort with the familiar such as family, friends and our homes. We create homes that are designed a certain way and usually are slow to change. We make friends for years and keep those memories etched in stone, even though time and age create a romanticised version of the past. Change scares us so much that we reflect on our past, the old days, with such reverence that we paint over the ugly parts...
December 1, 2016: Science Progress
https://www.readbyqxmd.com/read/28741081/capuchin-monkeys-use-of-human-and-conspecific-cues-to-solve-a-hidden-object-choice-task
#3
Jennifer L Essler, Lindsay P Schwartz, Mattea S Rossettie, Peter G Judge
Learning by watching others can provide valuable information with adaptive consequences, such as identifying the presence of a predator or locating a food source. The extent to which nonhuman animals can gain information by reading the cues of others is often tested by evaluating responses to human gestures, such as a point, and less often evaluated by examining responses to conspecific cues. We tested whether ten brown capuchin monkeys (Cebus [Sapajus] apella) were able to use cues from monkeys and a pointing cue from a human to obtain hidden rewards...
July 24, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28741028/transfer-of-time-based-task-expectancy-across-different-timing-environments
#4
Stefanie Aufschnaiter, Andrea Kiesel, Roland Thomaschke
Recent research on time-based expectancy has shown that humans base their expectancies for responses on representations of temporal relations (e.g., shorter vs. longer duration), rather than on representations of absolute durations (e.g., 500 vs. 1000 ms). In the present study, we investigated whether this holds also true for time-based expectancy of tasks instead of responses. Using a combination of the time-event correlation paradigm and the standard task-switching paradigm, participants learned to associate two different time intervals with two different tasks in a learning phase...
July 24, 2017: Psychological Research
https://www.readbyqxmd.com/read/28740664/development-of-a-novel-ex-vivo-porcine-laparoscopic-heller-myotomy-and-nissen-fundoplication-training-model-toronto-lap-nissen-simulator
#5
Hideki Ujiie, Tatsuya Kato, Hsin-Pei Hu, Patrycja Bauer, Priya Patel, Hironobu Wada, Daiyoon Lee, Kosuke Fujino, Colin Schieman, Andrew Pierre, Thomas K Waddell, Shaf Keshavjee, Gail E Darling, Kazuhiro Yasufuku
BACKGROUND: Surgical trainees are required to develop competency in a variety of laparoscopic operations. Developing laparoscopic technical skills can be difficult as there has been a decrease in the number of procedures performed. This study aims to develop an inexpensive and anatomically relevant model for training in laparoscopic foregut procedures. METHODS: An ex vivo, anatomic model of the human upper abdomen was developed using intact porcine esophagus, stomach, diaphragm and spleen...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28736771/on-interestingness-measures-for-mining-statistically-significant-and-novel-clinical-associations-from-emrs
#6
Orhan Abar, Richard J Charnigo, Abner Rayapati, Ramakanth Kavuluru
Association rule mining has received significant attention from both the data mining and machine learning communities. While data mining researchers focus more on designing efficient algorithms to mine rules from large datasets, the learning community has explored applications of rule mining to classification. A major problem with rule mining algorithms is the explosion of rules even for moderate sized datasets making it very difficult for end users to identify both statistically significant and potentially novel rules that could lead to interesting new insights and hypotheses...
October 2016: ACM-BCB: ACM Conference on Bioinformatics, Computational Biology and Biomedicine
https://www.readbyqxmd.com/read/28736770/classification-of-helpful-comments-on-online-suicide-watch-forums
#7
Ramakanth Kavuluru, Amanda G Williams, María Ramos-Morales, Laura Haye, Tara Holaday, Julie Cerel
Among social media websites, Reddit has emerged as a widely used online message board for focused mental health topics including depression, addiction, and suicide watch (SW). In particular, the SW community/subreddit has nearly 40,000 subscribers and 13 human moderators who monitor for abusive comments among other things. Given comments on posts from users expressing suicidal thoughts can be written from any part of the world at any time, moderating in a timely manner can be tedious. Furthermore, Reddit's default comment ranking does not involve aspects that relate to the "helpfulness" of a comment from a suicide prevention (SP) perspective...
October 2016: ACM-BCB: ACM Conference on Bioinformatics, Computational Biology and Biomedicine
https://www.readbyqxmd.com/read/28736474/phenotype-analysis-of-early-risk-factors-from-electronic-medical-records-improves-image-derived-diagnostic-classifiers-for-optic-nerve-pathology
#8
Shikha Chaganti, Kunal P Nabar, Katrina M Nelson, Louise A Mawn, Bennett A Landman
We examine imaging and electronic medical records (EMR) of 588 subjects over five major disease groups that affect optic nerve function. An objective evaluation of the role of imaging and EMR data in diagnosis of these conditions would improve understanding of these diseases and help in early intervention. We developed an automated image-processing pipeline that identifies the orbital structures within the human eyes from computed tomography (CT) scans, calculates structural size, and performs volume measurements...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28736170/overlap-among-spatial-memories-triggers-repulsion-of-hippocampal-representations
#9
Avi J H Chanales, Ashima Oza, Serra E Favila, Brice A Kuhl
Across the domains of spatial navigation and episodic memory, the hippocampus is thought to play a critical role in disambiguating (pattern separating) representations of overlapping events. However, it is not fully understood how and why hippocampal patterns become separated. Here, we test the idea that event overlap triggers a "repulsion" among hippocampal representations that develops over the course of learning. Using a naturalistic route-learning paradigm and spatiotemporal pattern analysis of human fMRI data, we found that hippocampal representations of overlapping routes gradually diverged with learning to the point that they became less similar than representations of non-overlapping events...
July 15, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28735144/entorhinal-tau-pathology-disrupts-hippocampal-prefrontal-oscillatory-coupling-during-associative-learning
#10
Stephanie E Tanninen, Bardia Nouriziabari, Mark D Morrissey, Rami Bakir, Robert D Dayton, Ronald L Klein, Kaori Takehara-Nishiuchi
A neural signature of asymptomatic preclinical Alzheimer's disease (AD) is disrupted connectivity between brain regions; however, its underlying mechanisms remain unknown. Here, we tested whether a preclinical pathologic feature, tau aggregation in the entorhinal cortex (EC) is sufficient to disrupt the coordination of local field potentials (LFPs) between its efferent regions. P301L-mutant human tau or green fluorescent protein (GFP) was virally overexpressed in the EC of adult rats. LFPs were recorded from the dorsal hippocampus and prelimbic medial prefrontal cortex while the rats underwent trace eyeblink conditioning where they learned to associate 2 stimuli separated by a short time interval...
July 6, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28734837/neural-reuse-of-action-perception-circuits-for-language-concepts-and-communication
#11
REVIEW
Friedemann Pulvermüller
Neurocognitive and neurolinguistics theories make explicit statements relating specialized cognitive and linguistic processes to specific brain loci. These linking hypotheses are in need of neurobiological explanation. Recent mathematical models of human language mechanisms constrained by fundamental neuroscience principles and established knowledge about comparative neuroanatomy offer explanations for where, when and how language is processed in the human brain. In these models, network structure and connectivity along with action- and perception-induced correlation of neuronal activity co-determine neurocognitive mechanisms...
July 19, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28734509/global-disability-empowering-children-of-all-abilities
#12
REVIEW
Rebecca J Scharf, Angelina Maphula, Paige C Pullen, Rita Shrestha, Gaynell Paul Matherne, Reeba Roshan, Beena Koshy
Worldwide, children are often not meeting their developmental potential owing to malnutrition, infection, lack of stimulation, and toxic stress. Children with disabilities are more likely to experience poverty, neglect, and abuse, and are less likely to have adequate access to education and medical care. Early childhood developmental stimulation can improve language, learning, and future participation in communities. Therapeutic supports and endeavors to reduce stigma for people of all abilities strengthen communities and allow for human thriving...
August 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/28733591/predictive-and-tempo-flexible-synchronization-to-a-visual-metronome-in-monkeys
#13
Ryuji Takeya, Masashi Kameda, Aniruddh D Patel, Masaki Tanaka
Predictive and tempo-flexible synchronization to an auditory beat is a fundamental component of human music. To date, only certain vocal learning species show this behaviour spontaneously. Prior research training macaques (vocal non-learners) to tap to an auditory or visual metronome found their movements to be largely reactive, not predictive. Does this reflect the lack of capacity for predictive synchronization in monkeys, or lack of motivation to exhibit this behaviour? To discriminate these possibilities, we trained monkeys to make synchronized eye movements to a visual metronome...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733358/pattern-analyses-reveal-separate-experience-based-fear-memories-in-the-human-right-amygdala
#14
Senne Braem, Jan De Houwer, Jelle Demanet, Kenneth S L Yuen, Raffael Kalisch, Marcel Brass
Learning fear via the experience of contingencies between a conditioned stimulus (CS) and an aversive unconditioned stimulus (US) is often assumed to be fundamentally different from learning fear via instructions. An open question is whether fear-related brain areas respond differently to experienced CS-US contingencies than to merely instructed CS-US contingencies. Here, we contrasted two experimental conditions where subjects were instructed to expect the same CS-US contingencies while only one condition was characterized by prior experience with the CS-US contingency...
July 21, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28733248/pupil-dilations-induced-by-barely-conscious-reward-goal-priming
#15
Yudai Takarada, Daichi Nozaki
The topic of unconscious influences on behavior has long been explored as a way of understanding human performance and the neurobiological correlates of intention, motivation and action. Previous research using transcranial magnetic stimulation has demonstrated that barely visible priming of an action concept, when combined with reward in the form of a consciously perceived positive stimulus, can alter the state of the motor system and enhance the maximal voluntary force level. One possible explanation is that positive stimulus-induced reward signals are processed by the dopaminergic system in the basal ganglia, motivating individuals to increase the effort they invest in particular behaviors, or to recruit the resources necessary for maintaining those behaviors...
July 18, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28732303/do-analog-number-representations-underlie-the-meanings-of-young-children-s-verbal-numerals
#16
Susan Carey, Anna Shusterman, Paul Haward, Rebecca Distefano
Children learn to count, and even learn the cardinal meanings of the first three or four verbal numerals ("one" through "three" or "four"), before they master the numerical significance of counting. If so, it follows that the cardinal meanings of those first few numerals cannot be derived, initially, from their place in the count list and the counting routine. What non-verbal representations, then, support the cardinal meanings of verbal numerals before children have mastered how counting does so? Four experiments addressed the commonly adopted assumption that in the earliest period of learning the meanings of number words, children map verbal numerals to regions of the analog number system (ANS), a system of representation with numerical content that is widely attested in animals and in human infants...
July 18, 2017: Cognition
https://www.readbyqxmd.com/read/28731839/cost-benefit-arbitration-between-multiple-reinforcement-learning-systems
#17
Wouter Kool, Samuel J Gershman, Fiery A Cushman
Human behavior is sometimes determined by habit and other times by goal-directed planning. Modern reinforcement-learning theories formalize this distinction as a competition between a computationally cheap but inaccurate model-free system that gives rise to habits and a computationally expensive but accurate model-based system that implements planning. It is unclear, however, how people choose to allocate control between these systems. Here, we propose that arbitration occurs by comparing each system's task-specific costs and benefits...
July 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28731432/multivariate-approach-for-alzheimer-s-disease-detection-using-stationary-wavelet-entropy-and-predator-prey-particle-swarm-optimization
#18
Yudong Zhang, Shuihua Wang, Yuxiu Sui, Ming Yang, Bin Liu, Hong Cheng, Junding Sun, Wenjuan Jia, Preetha Phillips, Juan Manuel Gorriz
BACKGROUND: The number of patients with Alzheimer's disease is increasing rapidly every year. Scholars often use computer vision and machine learning methods to develop an automatic diagnosis system. OBJECTIVE: In this study, we developed a novel machine learning system that can make diagnoses automatically from brain magnetic resonance images. METHODS: First, the brain imaging was processed, including skull stripping and spatial normalization...
July 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28731306/historical-view-on-lead-guidelines-and-regulations
#19
Hana R Pohl, Susan Z Ingber, Henry G Abadin
Lead has been used in many commodities for centuries. As a result, human exposure has occurred through the production and use of these lead-containing products. For example, leaded gasoline, lead-based paint, and lead solder/pipes in water distribution systems have been important in terms of exposure potential to the general population. Worker exposures occur in various industrial activities such as lead smelting and refining, battery manufacturing, steel welding or cutting operations, printing, and construction...
April 10, 2017: Metal Ions in Life Sciences
https://www.readbyqxmd.com/read/28731294/the-bioinorganic-chemistry-of-lead-in-the-context-of-its-toxicity
#20
Wolfgang Maret
Owing to its abundance on earth and its multiple uses by humans, lead (Pb) is a major toxicant that has threatened human health for millennia and continues to do so. There is no safe level of exposure, necessitating a nuanced approach to its control in the food we consume, the water we drink, and the air we breathe. Turnover in soft tissues is within days. In contrast, lead accumulates in bone and turns over with a half-life of about 30 years, though it can be mobilized from bone under physiological and pathophysiological conditions of bone resorption...
April 10, 2017: Metal Ions in Life Sciences
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