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Artificial disc

Qingpeng Song, Wei Tian, Da He, Xiao Han, Ning Zhang, Jinchao Wang, Zuchang Li
Objective: To evaluate the long-term efficacy and influencing factors of cervical artificial disc replacement (CADR) for patients with cervical spondylotic radiculopathy (CSR). Methods: The data of 29 CSR patients who underwent Bryan artificial disc replacement between December 2003 and December 2007 and followed up more than 10 years were retrospectively analysed. There were 16 males and 13 females with an average age of 54.1 years (range, 40-70 years). The disease duration was 2-144 months (mean, 19...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
My Pham, Kevin Phan, Ian Teng, Ralph J Mobbs
OBJECTIVE: Cervical spondylosis affects a huge proportion of the middle-aged population. Degenerative changes can occur in multiple regions of the cervical spine typically affecting the joints, intervertebral discs and endplates. These changes lead to compression of adjacent nervous structures, which results in radiculopathic and myelopathic pain. Various treatment modalities are currently available with non-surgical approaches the initial go to if there is no symptomatic cord compression...
May 2018: Orthopaedic Surgery
Luiza Pereira Dias da Cruz, Robert G Hill, Xiaojing Chen, David G Gillam
There are numerous over-the-counter (OTC) and professionally applied (in-office) products and techniques currently available for the treatment of dentine hypersensitivity (DH), but more recently, the use of bioactive glasses in toothpaste formulations have been advocated as a possible solution to managing DH. Aim . The aim of the present study, therefore, was to compare several bioactive glass formulations to investigate their effectiveness in an established in vitro model. Materials and Methods . A 45S5 glass was synthesized in the laboratory together with several other glass formulations: (1) a mixed glass (fluoride and chloride), (2) BioMinF, (3) a chloride glass, and (4) an amorphous chloride glass...
2018: International Journal of Dentistry
Qingpeng Song, Wei Tian, Da He, Xiao Han, Ning Zhang, Jinchao Wang, Zuchang Li, Xiao Feng
Objective: To evaluate the influence of the shell angle of cervical artificial disc on long-term effectiveness of cervical artificial disc replacement (CADR). Methods: The clinical data of 71 patients who were treated with single-level CADR with Bryan prosthesis between December 2003 and December 2007 and followed up more than 10 years, were retrospectively analyzed. There were 44 males and 27 females with an age of 26-69 years (mean, 45.9 years). According to the shell angle of the cervical artificial disc which was measured on the postoperative lateral X-ray film, the patients were divided into kyphotic group (shell angle was negative) and non-kyphotic group...
May 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
Yang Meng, Xiaofei Wang, Zhengyang Zhao, Beiyu Wang, Tingkui Wu, Hao Liu
BACKGROUND: Two-level artificial cervical disc replacement (ACDR) is gaining attention because of its unique advantages. Among the artificial discs designed for use in ACDR, the Prestige-LP cervical disc is widely used and FDA approved. However, there are no standard implantation sequences for two-level ACDR using the Prestige-LP disc, and complications due to inappropriate implantation sequences remain unknown. CASE DESCRIPTION: A 45-year-old female underwent continuous, two-level ACDR using the Prestige-LP disc and experienced anterior migration of a previously inserted artificial disc after secondary disc implantation at an upper segment due to an inappropriate implantation sequence during surgery...
May 23, 2018: World Neurosurgery
Vineet Tyagi, Russell Strom, Omar Tanweer, Anthony K Frempong-Boadu
Fusion and rigid instrumentation have been the mainstay for the surgical treatment of degenerative diseases of the spine for many years. Dynamic stabilization provides a theoretical advantage of decreased biomechanical stress on adjacent spinal segments and decreased fatigue failure of implants. Artificial discs provide an alternative treatment and have been well-studied in the literature. Another technology that is currently used in Europe but rarely in the USA is flexible rods attached to pedicle screws instead of rigid rods or bone fusion...
June 2018: Bulletin of the Hospital for Joint Diseases
Q P Song, W Tian, D He, X Han, N Zhang, J C Wang, Z C Li
Objective: To evaluate the long-term efficacy of cervical artificial disc replacement for patients with cervical disc herniation and degenerative cervical canal stenosis. Methods: Total of sixty-eight patients underwent single-level Bryan artificial disc replacement in Beijing Jishuitan Hospital from December 2003 to December 2007 with a minimum 10-year follow-up were retrospectively analyzed. There were 43 males and 25 females with a mean age of (46±8) years. According to preoperative CT and MRI, the patients were divided into two groups: 27 patients in cervical disc herniation group and 41 patients in degenerative cervical canal stenosis group...
May 8, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
David Nečas, Martin Vrbka, Ivan Křupka, Martin Hartl
The paper introduces an experimental investigation of frictional behaviour of materials used for joint replacements. The measurements were performed using a ball-on-disc tribometer, while four material combinations were tested; metal-on-metal, ceramic-on-ceramic, metal-on-polyethylene, and ceramic-on-polyethylene, respectively. The contact was lubricated by pure saline and various protein solutions. The experiments were realized at two mean speeds equal to 5.7 mm/s and 22 mm/s and two slide-to-roll ratios, −150% and 150%...
May 10, 2018: Materials
A L Reyaz, N Balakrishnan, V Udayasuriyan
The pink bollworm (PBW), Pectinophora gossypiella (Saund.) does not feed on leaves in natural circumstances. We made an attempt with the first instar larva (5 days old) and found it eats the leaf in the absence of other foods. Utilizing this new feeding behaviour, a simple methodology was developed for screening of resistance in PBW against Bt cotton plants. The PBW collected from BGII Bt cotton fields (BGII-resistant population) and NBAIR culture (susceptible population) were reared under laboratory conditions for two generations...
May 2018: 3 Biotech
A Lucchese, A Bertacci, S Zanna, S Chersoni, M Manuelli, A Visone, D Moro, G Valdrè
This study aims to evaluate the effectiveness in reducing dentine permeability of three different toothpastes comparing with a sodium fluoride one. Dentine permeability was measured by a fluid filtration system. Dentin discs were randomized in four experimental groups and treated with different commercial toothpastes, as it follows. Group A: Sensodyne® Rapid, with strontium acetate; group B: Elmex Sensitive ProfessionalTM, with arginine and 450 ppm monofluoro-phosphate; group C: Colgate Total Advanced®, with 1450 ppm NaF; group D: AZ Pro-Expert®, with 1100 ppm SnF2...
March 2018: Journal of Biological Regulators and Homeostatic Agents
Diana G Soares, Giovanna Anovazzi, Ester Alves F Bordini, Uxua O Zuta, Maria Luísa A Silva Leite, Fernanda G Basso, Josimeri Hebling, Carlos A de Souza Costa
INTRODUCTION: The improvement of biomaterials capable of driving the regeneration of the pulp-dentin complex mediated by resident cells is the goal of regenerative dentistry. In the present investigation, a chitosan scaffold (CHSC) that released bioactive concentrations of simvastatin (SIM) was tested, aimed at the development of a cell-free tissue engineering system. METHODS: First, we performed a dose-response assay to select the bioactive dose of SIM capable of inducing an odontoblastic phenotype in dental pulp cells (DPCs); after which we evaluated the synergistic effect of this dosage with the CHSC/DPC construct...
June 2018: Journal of Endodontics
Yang Li, Jia Zhu, Zhenhua Liao, Zhenjun Zhang, Weiqiang Liu
OBJECTIVE: To systematically investigate the effect of 3-level hybrid constructs on the cervical spine biomechanics based on a validated model of the C3-C7 segments. METHODS: Three hybrid constructs with 2 U-shaped dynamic cervical implants and 1 cage were simulated. The 3 constructs were 1) Cage-U-U (cage implanted at the C3-C4 level and U-shaped dynamic cervical implants implanted at the C4-C5 and C5-C6 levels), 2) U-Cage-U, and 3) U-U-Cage. Biomechanical parameters including moments, cervical motions, and stresses in the facet and implants were analyzed in flexion and extension...
June 2018: World Neurosurgery
Miguel Gonzalez-Andrades, Roholah Sharifi, Mohammad-Mirazul Islam, Thibaut Divoux, Michael Haist, Eleftherios Paschalis, Larisa Gelfand, Shamina Mamodaly, Luca Di Cecilia, Andrea Cruzat, Franz-Josef Ulm, James Chodosh, Francois Delori, Claes H Dohlman
PURPOSE: To make the Boston keratoprosthesis (B-KPro), together with its carrier corneal graft, more easily procured, transported and stored, as well as less expensive, easier for the surgeon to implant and safer for the patient, it is proposed that the B-KPro-graft combination be pre-assembled by an expert technician, followed by sterilization with gamma ray irradiation (GI) allowing long-term storage at room temperature. For this to be possible, it must be shown that the B-KPro itself (not only the graft) remains unharmed by the irradiation...
April 5, 2018: Ocular Surface
Junichi Kushioka, Takashi Kaito, Takahiro Makino, Hiroyasu Fujiwara, Hiroyuki Tsukazaki, Shota Takenaka, Yusuke Sakai, Hideki Yoshikawa
BACKGROUND: Lateral inter-body fusion (LIF) using cages with a large bone grafting space can lead to a shortage of autologous grafting materials. The use of artificial bone is an option to increase the volume of grafting materials. However, the rate of bony fusion for these materials compared to that of autologous bone is unclear. METHODS: The bone fusion rate for artificial bone (HAp/Col) and autologous iliac bone (IBG) graft among 23 patients who had undergone LIF (total 66 disc levels) combined with multilevel posterior corrective fusion for the treatment of adult spinal deformity was retrospectively evaluated...
April 4, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
Michael P Kelly, Claire D Eliasberg, Max S Riley, Remi M Ajiboye, Nelson F SooHoo
PURPOSE: The aim of this study was to analyze rates of perioperative complications and subsequent cervical surgeries in patients treated for cervical degenerative disc disease with anterior cervical discectomy and fusion (ACDF) and those treated with artificial cervical disc arthroplasty (ACDA) for up to 5-year follow-up. METHODS: California's Office of Statewide Health Planning and Development discharge database was analyzed for patients aged 18-65 years undergoing single-level ACDF or ACDA between 2003 and 2010...
June 2018: European Spine Journal
He Zhao, Li-Jun Duan, Yu-Shan Gao, Yong-Dong Yang, Xiang-Sheng Tang, Ding-Yan Zhao, Yang Xiong, Zhen-Guo Hu, Chuan-Hong Li, Xing Yu
BACKGROUND: Nowadays, anterior cervical artificial disc replacement (ACDR) has achieved favorable outcomes in treatment for patients with single-level cervical spondylosis. However, It is still controversial that whether or not it will become a potent therapeutic alternation in treating 2 contiguous levels cervical spondylosis compared with anterior cervical decompression and fusion (ACDF). Therefore, we conducted a systematic review and meta-analysis to compare the efficacy and safety of ACDR and ACDF in patients with 2 contiguous levels cervical spondylosis...
March 2018: Medicine (Baltimore)
Yan-Yan Bian, Lei Zhou, Gang Zhou, Zhong-Min Jin, Shi-Xuan Xin, Zi-Kai Hua, Xi-Sheng Weng
Ultra-low-wear polyethylene (ULWPE) is a new type polyethylene made by experts who are from China petrochemical research institute, which is easy to process and implant. Preliminary test showed it was more resistant to wear than that of Ultra-high-molecular weight polyethylene (UHMWPE). The purpose of the research is to study biocompatibility, bio-tribological properties and debris characterization of ULWPE. Cytotoxicity test, hemolysis test, acute/chronic toxicity and muscular implantation test were conducted according to national standard GB/T-16886/ISO-10993 for evaluation requirements of medical surgical implants...
June 2018: Journal of the Mechanical Behavior of Biomedical Materials
Jin Huang, Wan Tang, Shengquan Zhu, Meini Du
Butyric acid (C3 H7 COOH) is an important chemical that is widely used in foodstuffs along with in the chemical and pharmaceutical industries. The bioproduction of butyric acid through large-scale fermentation has the potential to be more economical and efficient than petrochemical synthesis. In this paper, the metabolic pathways involved in the production of butyric acid from Clostridium tyrobutyricum using hexose and pentose as substrates are investigated, and approaches to enhance butyric acid production through genetic modification are discussed...
May 28, 2018: Preparative Biochemistry & Biotechnology
Yad Ram Yadav, Shailendra Ratre, Vijay Parihar, Amitesh Dubey, Mashoo N Dubey
Symptomatic ventral cervical cord compressions have been treated by anterior discectomy with fusion, anterior corpectomy and fusion, discectomy with an artificial disc, and minimally invasive techniques. There are complications associated with the fusion procedure, especially when a long segment fusion is undertaken. Partial removal of the vertebral body without fusion could help in avoiding fusion and its associated complications. We are describing the detailed surgical technique, indications, limitations, and early results of endoscopic partially corpectomy...
March 2018: Neurology India
Yu Moriguchi, Dae-Sung Lee, Ryota Chijimatsu, Khair Thamina, Kazuto Masuda, Dai Itsuki, Hideki Yoshikawa, Satoshi Hamaguchi, Akira Myoui
In the physiochemical sciences, plasma is used to describe an ionized gas. Previous studies have implicated plasma surface treatment in the enhancement of hydrophilicity of implanted musculoskeletal reconstructive materials. Hydroxyapatite (HA) ceramics, widely used in bone tissue regeneration, have made great advancements to skeletal surgery. In the present study, we investigate the impact of low-pressure plasma on the interconnected porous calcium hydroxyapatite (IP-CHA) both in vitro and in vivo. Our results indicate that dielectric barrier discharge (DBD) plasma, when used with oxygen, can augment the hydrophilicity of non-porous HA surfaces and the osteoconductivity of the IP-CHA disc via increased water penetration of inner porous structures, as demonstrated through microfocus computed tomography (μCT) assay...
2018: PloS One
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