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https://www.readbyqxmd.com/read/28091786/a-new-look-at-the-drug-resistance-investigation-of-uropathogenic-e-coli-strains
#1
Wioletta Adamus-Białek, Łukasz Lechowicz, Anna B Kubiak-Szeligowska, Monika Wawszczak, Ewelina Kamińska, Magdalena Chrapek
Bacterial drug resistance and uropathogenic tract infections are among the most important issues of current medicine. Uropathogenic Escherichia coli strains are the primary factor of this issue. This article is the continuation of the previous study, where we used Kohonen relations to predict the direction of drug resistance. The characterized collection of uropathogenic E. coli strains was used for microbiological (the disc diffusion method for antimicrobial susceptibility testing), chemical (ATR/FT-IR) and mathematical (artificial neural networks, Ward's hierarchical clustering method, the analysis of distributions of inhibition zone diameters for antibiotics, Cohen's kappa measure of agreement) analysis...
January 13, 2017: Molecular Biology Reports
https://www.readbyqxmd.com/read/28042725/stepwise-illustration-of-teeth-fixation-semi-constrained-cervical-disc-arthroplasty
#2
Chih-Chang Chang, Jau-Ching Wu, Peng-Yuan Chang, Mei-Yin Yeh, Yi-Hsuan Kuo, Li-Yu Fay, Tsung-Hsi Tu, Wen-Cheng Huang, Henrich Cheng
There are many kinds of artificial discs available for cervical disc arthroplasty (CDA), with various designs of fixation and articulation mechanisms. Each of these designs has different features and theoretically fits most optimally in selected types of patients. However, there has been insufficient literature to guide individualized selection among these CDA devices. Since CDA aims to restore the joint function rather than arthrodesis, tailor-made size, shape, and mechanical properties should be taken into account for each candidate's target disc...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28042722/m6-c-artificial-disc-placement
#3
Domagoj Coric, John Parish, Margaret O Boltes
There has been a steady evolution of cervical total disc replacement (TDR) devices over the last decade resulting in surgical technique that closely mimics anterior cervical discectomy and fusion as well as disc design that emphasizes quality of motion. The M6-C TDR device is a modern-generation artificial disc composed of titanium endplates with tri-keel fixation as well as a polyethylene weave with a polyurethane core. Although not yet approved by the FDA, M6-C has finished a pilot and pivotal US Investigational Device Exemption (IDE) study...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28042721/surgical-technique-for-revision-surgery-of-cervical-artificial-disc-replacements
#4
Julia Onken, Bernhard Meyer, Peter Vajkoczy
OBJECTIVE Cervical artificial disc replacement (C-ADR) is a widely used procedure with low risk at implantation. Few cases have been reported about the surgical techniques of C-ADR revision. The authors describe their surgical experience with the explantation of a Galileo C-ADR. METHODS Revision surgery was performed in a 58-year-old patient. Patient positioning and surgical opening techniques were performed as appropriate for anterior cervical decompression. RESULTS Revision surgery via the initial anterior approach was successful following an atraumatic removal of the implant...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28042720/resection-of-uncovertebral-joints-and-posterior-longitudinal-ligament-for-cervical-disc-arthroplasty
#5
Tsung-Hsi Tu, Chih-Chang Chang, Jau-Ching Wu, Li-Yu Fay, Wen-Cheng Huang, Henrich Cheng
The most commonly accepted indications for cervical disc arthroplasty (CDA) are 1- and 2-level cervical disc herniation or spondylosis causing radiculopathy or myelopathy that is refractory to medical management. Unlike anterior cervical discectomy and fusion (ACDF), which eliminates motion, CDA aims to restore the physiological range of motion of the indexed joint. Thus, the effect of indirect decompression gained by the insertion of a sufficiently large interbody graft and incorporation into arthrodesis after ACDF cannot be duplicated for CDA...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28032699/an-analysis-of-paravertebral-ossification-in-cervical-artificial-disc-replacement-a-novel-classification-based-on-computed-tomography
#6
Wei Tian, Ming-Xing Fan, Ya-Jun Liu, Xiao Han, Kai Yan, Han Wang, Yan-Wei Lyu
OBJECTIVE: Cervical artificial disc replacement (CADR) is a new technology in cervical spine surgery. However, CADR may result in paravertebral ossification (PO) after surgery and affect the mobility of the related spinal segments. The present widely used assessment method based on X-ray tomography cannot provide the position information of PO, and also PO detection rates by X-ray are low. The incidence of PO varies dramatically between studies. This study built a novel classification system based on cervical computer tomography (CT) scan to re-evaluate the incidence of PO and its influence on CADR, and also analyzed the predisposing factors of PO...
November 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28019063/interaction-of-transgenic-and-natural-insect-resistance-mechanisms-against-spodoptera-littoralis-in-cotton
#7
Steffen Hagenbucher, Michael Eisenring, Michael Meissle, Jörg Romeis
BACKGROUND: Insect-resistant transgenic plants that express insecticidal Cry proteins from Bacillus thuringiensis (Bt), are grown on millions of hectares worldwide. While these proteins are efficient in controlling key lepidopteran pests, not all pests are affected and the development of resistance in target pests is always a danger. These short-comings could be supplemented by exploiting the natural insect resistance of cotton, especially inducible terpenoids like gossypol. RESULTS: To assess the potential of gossypol in supplementing Cry proteins as a resistance-trait, we conducted a range of feeding assays with Spodoptera littoralis using artificial diet with defined amounts of Cry proteins and gossypol...
December 26, 2016: Pest Management Science
https://www.readbyqxmd.com/read/28002363/comparison-of-outcomes-of-single-level-anterior-cervical-discectomy-with-fusion-and-single-level-artificial-cervical-disc-replacement-for-single-level-cervical-degenerative-disc-disease
#8
Praveen Kumar Pandey, Inder Pawar, Jyoti Gupta, Raaghav Rai Verma
STUDY DESIGN: A single-center, prospective comparative study of prospectively collected outcomes, with a minimum 12 months follow-up. OBJECTIVES: The primary purpose of the study is to investigate the clinical, functional, and radiological outcomes of cervical total disc replacement (CTDR) in comparison with anterior cervical discectomy and fusion (ACDF) in the treatment of single-level cervical disc degenerative disease, prospectively. SUMMARY OF BACKGROUND DATA: CTDR has recently been an alternative to ACDF in cervical disc degenerative disease to preserve the motion at the treated level...
January 1, 2017: Spine
https://www.readbyqxmd.com/read/27939974/revision-surgeries-following-artificial-disc-replacement-of-cervical-spine
#9
Jong-Beom Park, Han Chang, Jin S Yeom, Kyung-Soo Suk, Dong-Ho Lee, Jae Chul Lee
OBJECTIVE: We investigated causes and results of revision surgeries after artificial disc replacement of cervical spine (C-ADR). METHODS: Twenty-one patients (mean age: 52.8) who underwent revision surgery after C-ADR and who had a minimum 2-year of follow-up were included into this study. The mean time between the primary and revision surgeries was 21 months. During their primary surgeries, 14 patients underwent single level C-ADR, 2 two-level C-ADR, and 5 two-level hybrid surgery for 16 radiculopathy, 3 myelopathy, and 2 adjacent segment diseases...
December 8, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27928240/color-stability-of-nanofilled-and-microhybrid-resin-based-composites-following-exposure-to-chlorhexidine-mouthrinses-an-in-vitro-study
#10
Mahmood Khosravi, Behnaz Esmaeili, Forough Nikzad, Soraya Khafri
OBJECTIVES: This study aimed to evaluate the effects of chlorhexidine mouthrinses on color stability of nanofilled and micro-hybrid resin-based composites. MATERIALS AND METHODS: In this in-vitro study, 160 disc-shaped specimens (7x2mm) were fabricated of Filtek Z250 and Filtek Z350XT Enamel (A2 shade). The samples of each group were randomly divided into eight subgroups (n=10). The specimens were incubated in artificial saliva at 37°C for 24 hours. The baseline color values (L*, a*, b*) of each specimen were measured according to CIE LAB system using a reflection spectrophotometer...
March 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/27928237/effect-of-accelerated-artificial-aging-on-translucency-of-methacrylate-and-silorane-based-composite-resins
#11
Mehdi Shirinzad, Loghman Rezaei-Soufi, Maryam Sadat Mirtorabi, Farshid Vahdatinia
OBJECTIVES: Composite restorations must have tooth-like optical properties namely color and translucency and maintain them for a long time. This study aimed to compare the effect of accelerated artificial aging (AAA) on the translucency of three methacrylate-based composites (Filtek Z250, Filtek Z250XT and Filtek Z350XT) and one silorane-based composite resin (Filtek P90). MATERIALS AND METHODS: For this in vitro study, 56 composite discs were fabricated (n=14 for each group)...
March 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/27902945/artificial-cervical-disc-replacement-with-the-prestige-lp-prosthesis-for-the-treatment-of-non-contiguous-2-level-cervical-degenerative-disc-disease-a-minimum-24-month-follow-up
#12
Tingkui Wu, Beiyu Wang, Chen Ding, Yang Meng, Jigang Lou, Yi Yang, Hao Liu
OBJECTIVE: We describe the features of non-contiguous 2-level cervical degenerative disc disease (NCDDD), investigate the safety and feasibility of artificial cervical disc replacement (ACDR) for the treatment of NCDDD, and expect that our study will provide spine surgeons with an alternative procedure for NCDDD. METHODS: Twenty-five patients with NCDDD received ACDR with a Prestige-LP prosthesis. Clinical outcomes were evaluated using the 36-Short Form (SF-36, Mental Component Summary [MCS] and Physical Component Summary [PCS]), Visual Analog Scale (VAS), Japanese Orthopedic Association (JOA), and Neck Disability Index (NDI) scores...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27891466/an-in-vitro-evaluation-of-retention-colonization-and-penetration-of-commonly-used-denture-lining-materials-by-candida-albicans
#13
Sushma Krishnamurthy, Rajendra B Hallikerimath
INTRODUCTION: Colonization of the surface by Candida albicans and related Candida species is one of the major concerns of denture lining materials. AIM: We evaluated retention, colonization and penetration of the four denture lining materials namely Molloplast B, Permaflex, GC Soft Liner and Ufi Gel Hard C by Candida albicans. MATERIAL AND METHODS: a) Evaluation of retention: Five test discs of each material with smooth surface on one side and rough on the other were prepared and surface roughness (Ra) was measured with profilometer...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890691/minimum-four-year-subsequent-surgery-rates-of-cervical-disc-replacement-versus-fusion-a-meta-analysis-of-prospective-randomized-clinical-trials
#14
T K Wu, H Liu, B Y Wang, Y Meng
INSTRUCTION: Anterior cervical discectomy and fusion (ACDF) is a well-accepted surgical management strategy for radiculopathy and/or myelopathy. However, complications sometimes required subsequent surgery at the operated and adjacent levels. Artificial cervical disc replacement (ACDR) has been accepted as the most extensive non-fusion procedure and is designed to preserve motion. However, some specific complications can result in subsequent surgery, thus, attracting the attention of investigators...
November 24, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27888676/revision-surgery-for-cervical-artificial-disc-surgical-technique-and-clinical-results
#15
J Onken, A Reinke, J Radke, T Finger, S Bayerl, P Vajkoczy, B Meyer
OBJECTIVE: Cervical artificial disc replacement (C-ADR) was developed with the goal of preserving mobility of the cervical segment in patients with degenerative disc disease. So far, little is known about experiences with revision surgery and explantation of C-ADRs. Here, we report our experience with revision the third generation, Galileo-type disc prosthesis from a retrospective study of two institutions. PATIENTS AND METHODS: Between November 2008 and July 2016, 16 patients with prior implantation of C-ADR underwent removal of the Galileo-type disc prosthesis (Signus, Medizintechnik, Germany) due to a call back by industry...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27871028/microstructure-analysis-method-for-evaluating-degenerated-intervertebral-disc-tissue
#16
Andrea Friedmann, Felix Goehre, Christopher Ludtka, Thomas Mendel, Hans-Joerg Meisel, Andreas Heilmann, Stefan Schwan
Degeneration of intervertebral disc (IVD) tissue is characterized by several structural changes that result in variations in disc physiology and loss of biomechanical function. The complex process of degeneration exhibits highly intercorrelated biomechanical, biochemical, and cellular interactions. There is currently some understanding of the cellular changes in degenerated intervertebral disc tissue, but microstructural changes and deterioration of the tissue matrix has previously been rarely explored. In this work, sequestered IVD tissue was successfully characterized using histology, light microscopy, and scanning electron microscopy (SEM) to quantitatively evaluate parameters of interest for intervertebral disc degeneration (IDD) such as delamination of the collagenous matrix, cell density, cell size, and extra cellular matrix (ECM) thickness...
October 21, 2016: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/27836574/towards-bioreactor-development-with-physiological-motion-control-and-its-applications
#17
Marcus Stoffel, Wolfgang Willenberg, Marzieh Azarnoosh, Nadine Fuhrmann-Nelles, Bei Zhou, Bernd Markert
In biomedical applications bioreactors are used, which are able to apply mechanical loadings under cultivation conditions on biological tissues. However, complex mechanobiological evolutions, such as the dependency between mechanical properties and cell activity, depend strongly on the applied loading conditions. This requires correct physiological movements and loadings in bioreactors. The aim of the present study is to develop bioreactors, in which native and artificial biological tissues can be cultivated under physiological conditions in knee joints and spinal motion segments...
January 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27836147/effect-of-artificial-toothbrushing-and-water-storage-on-the-surface-roughness-and-micromechanical-properties-of-tooth-colored-cad-cam-materials
#18
Simon Flury, Elisabeth Diebold, Anne Peutzfeldt, Adrian Lussi
STATEMENT OF PROBLEM: Because of the different composition of resin-ceramic computer-aided design and computer-aided manufacturing (CAD-CAM) materials, their polishability and their micromechanical properties vary. Moreover, depending on the composition of the materials, their surface roughness and micromechanical properties are likely to change with time. PURPOSE: The purpose of this in vitro study was to investigate the effect of artificial toothbrushing and water storage on the surface roughness (Ra and Rz) and the micromechanical properties, surface hardness (Vickers [VHN]) and indentation modulus (EIT), of 5 different tooth-colored CAD-CAM materials when polished with 2 different polishing systems...
November 14, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27826089/ulf-fernstrom-1915-1985-and-his-contributions-to-the-development-of-artificial-disc-replacements-a-historical-vignette
#19
REVIEW
Christian Fisahn, Brittni Burgess, Joe Iwanaga, Jens R Chapman, Rod J Oskouian, R Shane Tubbs
INTRODUCTION: Artificial disc replacements, which serve the function of separating vertebrae to allow for proper spinal alignment, can help treat debilitating low back pain in patients who have failed other conservative methods of treatment. Ulf Fernstrom was the pioneer of artificial disc replacement, and his contribution in the way of Fernstrom "Balls" dramatically altered spinal surgery and technique by demonstrating the proper technique and implant that should be utilized for areas requiring motion in many planes...
November 5, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27807981/evaluation-of-aesculap-implant-systems-activl-artificial-disc-for-the-treatment-of-degenerative-disc-disease
#20
Daniel Shein, Jennifer Shue, Federico Girardi
A primary cause of chronic low back pain and disability is lumbar degenerative disc disease (DDD). Surgical treatments are available for DDD including fusion or lumbar total disc replacement (TDR). Lumbar TDR is performed as a motion-preserving alternative to lumbar fusion. There are several marketed lumbar TDR devices including the Aesculap Implant Systems activL Artificial Disc, Charité Artificial Disc and the ProDisc-L Total Disc Replacement. Areas covered: Considering the various surgical options by which lumbar DDD can be managed, here we evaluate the biologic and biomechanical benefits and concerns of the Aesculap activL Artificial Disc...
December 2016: Expert Review of Medical Devices
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