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https://www.readbyqxmd.com/read/29215782/the-effect-of-urinary-foley-catheter-substrate-material-on-the-antimicrobial-potential-of-calixerene-based-molecules
#1
A Guildford, C Morris, O Kitt, I Cooper
AIMS: This study was to investigate the antimicrobial activity of a modified calixarene polymer bound to a silicone substrate in the presence of pathogens associated with catheter infections, Escherichia coli and Proteus mirabilis. METHODS AND RESULTS: The molecule and its constituent parts, were studied bound and unbound to silicone substrates to ascertain growth effects. Minimum inhibitory and bactericidal concentrations were determined against E.coli and Pr.mirabilis...
December 7, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29192178/characterisation-of-porous-knitted-titanium-for-replacement-of-intervertebral-disc-nucleus-pulposus
#2
Gauri Tendulkar, Vrinda Sreekumar, Frank Rupp, Arun K Teotia, Kiriaki Athanasopulu, Ralf Kemkemer, Alfred Buck, Alfred Buck, Hans-Peter Kaps, Jürgen Geis-Gerstorfer, Ashok Kumar, Andreas K Nussler
Effective restoration of human intervertebral disc degeneration is challenged by numerous limitations of the currently available spinal fusion and arthroplasty treatment strategies. Consequently, use of artificial biomaterial implant is gaining attention as a potential therapeutic strategy. Our study is aimed at investigating and characterizing a novel knitted titanium (Ti6Al4V) implant for the replacement of nucleus pulposus to treat early stages of chronic intervertebral disc degeneration. Specific knitted geometry of the scaffold with a porosity of 67...
November 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29175428/developing-an-in-vitro-artificial-sebum-model-to-study-propionibacterium-acnes-biofilms
#3
Karl-Jan Spittaels, Tom Coenye
AIM: The aim of the present study was to develop a new model system to study Propionibacterium acnes biofilms. This model should be representative for the conditions encountered in the pilosebaceous unit. METHODS AND RESULTS: The new model, consists of an artificial sebum pellet supported by a silicone disc. Sebum pellets were inoculated with various P. acnes strains isolated from both normal and acneic skin. Growth and biofilm formation was verified by conventional plating at different time points, as well as by resazurin assays and fluorescence microscopy after LIVE/DEAD staining...
November 21, 2017: Anaerobe
https://www.readbyqxmd.com/read/29144007/analysis-of-surface-roughness-fracture-toughness-and-weibull-characteristics-of-different-framework-veneer-dental-ceramic-assemblies-after-grinding-polishing-and-glazing
#4
Guillermo Pradíes, Laura Godoy-Ruiz, Mutlu Özcan, Isabel Moreno-Hay, Francisco Martínez-Rus
PURPOSE: To compare the surface roughness and biaxial flexural strength of dental ceramics obtained after chairside surface modification by mechanical polishing procedures, versus laboratory reglazing. MATERIALS AND METHODS: Discs (16 × 1.5 ± 1.6 mm) (N = 90) of various framework-veneering combinations were fabricated: D/FC: lithium disilicate/feldspathic ceramic; Z/AL: zirconium dioxide/aluminous ceramic; N/FC: noble alloy/feldspathic ceramic; N/FF: noble alloy feldspathic with fluorapatite; B/FC: base alloy/feldspathic ceramic; B/FF: base alloy/feldspathic ceramic with fluorapatite...
November 16, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29142627/a-comparison-of-anterior-cervical-discectomy-and-fusion-versus-fusion-combined-with-artificial-disc-replacement-for-treating-3-level-cervical-spondylotic-disease
#5
Seo-Ryang Jang, Sang-Bok Lee, Kyoung-Suok Cho
Objective: The purpose of this study is to evaluate the efficacy and safety of 3-level hybrid surgery (HS), which combines fusion and cervical disc replacement (CDR), compared to 3-level fusionin patient with cervical spondylosis involving 3 levels. Methods: Patients in the anterior cervical discectomy and fusion (ACDF) group (n=30) underwent 3-level fusion and the HS group (n=19) underwent combined surgery with fusion and CDR. Clinical outcomes were evaluated using the visual analogue scale for the arm, the neck disability index (NDI), Odom criteria and postoperative complications...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29101314/clinical-and-radiological-analysis-of-bryan-cervical-artificial-disc-replacement-for-skip-multi-segment-cervical-spondylosis-long-term-follow-up-results
#6
Zikun Shang, Yingze Zhang, Di Zhang, Wenyuan Ding, Yong Shen
BACKGROUND The aim of this study was to retrospectively analyze the clinical and radiological efficacy of Bryan cervical artificial disc replacement (ADR) for "skip" multi-segment cervical spondylosis (SCS). MATERIAL AND METHODS We enrolled 49 patients with SCS treated with either Bryan cervical ADR (18 cases) or ACDF (31 cases). Each case was evaluated preoperatively and at more than 48 months postoperatively in follow-up using the JOA, NDI, and VAS. Cervical sagittal curvature, total cervical ROM, and degree of middle segments of motion were also evaluated...
November 4, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29097902/using-a-bayesian-network-to-predict-l5-s1-spinal-compression-force-from-posture-hand-load-anthropometry-and-disc-injury-status
#7
Richard E Hughes
Stochastic biomechanical modeling has become a useful tool most commonly implemented using Monte Carlo simulation, advanced mean value theorem, or Markov chain modeling. Bayesian networks are a novel method for probabilistic modeling in artificial intelligence, risk modeling, and machine learning. The purpose of this study was to evaluate the suitability of Bayesian networks for biomechanical modeling using a static biomechanical model of spinal forces during lifting. A 20-node Bayesian network model was used to implement a well-established static two-dimensional biomechanical model for predicting L5/S1 compression and shear forces...
2017: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/29097158/induction-of-liver-proliferation-using-a-polymeric-platform-in-mice
#8
Marcela Guimarães Takahashi de Lazari, Luciana Xavier Pereira, Celso Tarso Rodrigues Viana, Laura Alejandra Ariza Orellano, Simone Aparecida de Almeida, Anilton Cesar Vasconcelos, Giani Barbosa Ribeiro, Leticia Chinait Couto, Silvia Passos Andrade, Paula Peixoto Campos
AIMS: Currently, animal models of liver regeneration are based on extensive lesions of the native organ and on cellular approaches using biomaterials to host growth factors and extracellular components to create artificial liver systems. We report a polymeric biological platform, minimally invasive, that induced sequential proliferation of liver parenchyma inside the scaffold in mice. MAIN METHODS: Porous discs of polyether-polyurethane were surgically placed under the left liver lobe and removed at days 4, 8, 12 and 25 after implantation...
October 31, 2017: Life Sciences
https://www.readbyqxmd.com/read/29080374/the-unfolded-protein-response-mediated-by-perk-is-casually-related-to-the-pathogenesis-of-intervertebral-disc-degeneration
#9
Takeshi Fujii, Nobuyuki Fujita, Satoshi Suzuki, Takashi Tsuji, Takashi Takaki, Kazuo Umezawa, Kota Watanabe, Takeshi Miyamoto, Keisuke Horiuchi, Morio Matsumoto, Masaya Nakamura
Although the number of patients with intervertebral disc (IVD) degeneration is increasing in aging societies, its etiology and pathogenesis remain elusive and there is currently no effective treatment to prevent this undesirable condition. The unfolded protein response (UPR) is a cellular machinery that plays critical roles in handling endoplasmic reticulum (ER) stress, a condition caused by the accumulation of unfolded proteins in the ER lumen. This study aimed to elucidate the potential role of the UPR mediated by pancreatic endoplasmic reticulum kinase (PERK), one of the major ER stress sensors in mammalian cells, in the development of IVD degeneration...
October 28, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29076467/-analysis-of-the-results-of-total-cervical-disc-arthroplasty-using-a-m6-c-prosthesis-a-multicenter-study
#10
V A Byval'tsev, A A Kalinin, I A Stepanov, Yu Ya Pestryakov, V V Shepelev
Cervical spondylosis and intervertebral disc (IVD) degeneration are the most common cause for compression of the spinal cord and/or its roots. Total IVD arthroplasty, as a modern alternative to surgical treatment of IVD degeneration, is gaining popularity in many neurosurgical clinics around the world. Aim - the study aim was to conduct a multicenter analysis of cervical spine arthroplasty with an IVD prosthesis M6-C ('Spinal Kinetics', USA). MATERIAL AND METHODS: The study included 112 patients (77 males and 35 females)...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/29050419/successful-chilling-of-red-legged-partridge-alectoris-rufa-sperm-for-use-in-artificial-insemination
#11
J Santiago-Moreno, C Castaño, A Toledano-Díaz, M C Esteso, A López-Sebastián, S Villaverde-Morcillo, S G Dávila, M G Gil, E Blesbois
The fertilizing capacity of pure, fresh avian semen may disappear in just half an hour, hindering its successful use in artificial insemination (AI) projects. Longer storage requires the use of infra-physiological temperatures and of semen diluents that help preserve the spermatozoa but that do not interfere with their fertilizing capacity. This study examines the effect on sperm quality of storing red-legged partridge sperm for 3 h at 5°C with 2 different semen extenders: 1) a medium referred to as L&R-84, composed of sodium glutamate, glucose, magnesium acetate, potassium acetate, and polyvinylpyrrolidone, and 2) Lake 7...
September 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/29042733/effect-of-melaleuca-alternifolia-mixed-with-tissue-conditioners-in-varying-doses-on-colonization-and-inhibition-of-candida-albicans-an-in-vitro-study
#12
Siva Kumar Vankadara, Rajendra Basavaraj Hallikerimath, Viraj Patil, Kishore Bhat, Mallikarjun Hanumantappa Doddamani
AIMS AND OBJECTIVES: The study was conducted to evaluate the Colonization & Inhibition of Candida albicans in selected commercially available denture lining materials material by mixing them with varying concentrations and doses of tea tree oil. MATERIALS AND METHODS: Five test discs of 10mm diameter and 1.5mm thickness were prepared using commercially available soft denture lining materials (Viscogel and GC-soft). Tea tree oil of varying concentrations (10%, 20%, 30%, and 40%) and doses (0...
July 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29041323/boundary-element-method-for-2d-materials-and-thin-films
#13
M Hrtoň, V Křápek, T Šikola
2D materials emerge as a viable platform for the control of light at the nanoscale. In this context the need has arisen for a fast and reliable tool capable of capturing their strictly 2D nature in 3D light scattering simulations. So far, 2D materials and their patterned structures (ribbons, discs, etc.) have been mostly treated as very thin films of subnanometer thickness with an effective dielectric function derived from their 2D optical conductivity. In this study an extension to the existing framework of the boundary element method (BEM) with 2D materials treated as a conductive interface between two media is presented...
October 2, 2017: Optics Express
https://www.readbyqxmd.com/read/29019902/in-vitro-biomechanical-comparison-after-fixed-and-mobile-core-artificial-cervical-disc-replacement-versus-fusion
#14
COMPARATIVE STUDY
Jigang Lou, Yuanchao Li, Beiyu Wang, Yang Meng, Tingkui Wu, Hao Liu
In vitro biomechanical analysis after cervical disc replacement (CDR) with a novel artificial disc prosthesis (mobile core) was conducted and compared with the intact model, simulated fusion, and CDR with a fixed-core prosthesis. The purpose of this experimental study was to analyze the biomechanical changes after CDR with a novel prosthesis and the differences between fixed- and mobile-core prostheses.Six human cadaveric C2-C7 specimens were biomechanically tested sequentially in 4 different spinal models: intact specimens, simulated fusion, CDR with a fixed-core prosthesis (Discover, DePuy), and CDR with a mobile-core prosthesis (Pretic-I, Trauson)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28973309/nunec%C3%A2-cervical-disc-arthroplasty-improves-quality-of-life-in-cervical-radiculopathy-and-myelopathy-a-2-yr-follow-up
#15
Isobel Turner, David Choi
BACKGROUND: Anterior cervical disc replacement is an alternative to fusion for the treatment of selected cases of radiculopathy and myelopathy. We report clinical and radiological outcomes after disc replacement with the NuNec™ artificial cervical disc (Pioneer® Surgical Technology, Marquette, Michigan) with subgroup analysis. OBJECTIVE: To review clinical and radiological outcomes after anterior cervical disc replacement with the NuNec™ artificial cervical disc...
August 3, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28902569/a-new-classification-of-glaridacris-cooper-1920-cestoda-caryophyllidea-parasites-of-suckers-catostomidae-in-north-america-including-erection-of-a-new-genuspseudoglaridacris-n-gen
#16
Mikulas Oros, Dalibor Uhrovic, Tomáš Scholz
A taxonomic study of monozoic cestodes of the genus Glaridacris Cooper, 1920 (Cestoda: Caryophyllidea), parasites of catostomid fishes in North America, confirmed artificial character of the genus which is split to 2 different, morphologically distinct and not closely related genera. Glaridacris is newly circumscribed to include only 3 species, Glaridacris. catostomi Cooper, 1920 (type species), Glaridacris. terebrans (Linton, 1893) and Glaridacris. vogei Mackiewicz, 1976, which are characterized by an elongate body, a cuneiloculate or wedge-shaped scolex with six 6 shallow loculi, male and female gonopores at a distance from each other, follicular ovary and circum-medullary vitelline follicles (lateral and median)...
November 8, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28882520/dynamic-foraminal-dimensions-during-neck-extension-and-rotation-in-fusion-and-artificial-disc-replacement-an-observational-study
#17
Yener N Yeni, Timothy Baumer, Daniel Oravec, Azam Basheer, Colin P McDonald, Michael J Bey, Stephen W Bartol, Victor Chang
BACKGROUND: Changes in the dimensions of the cervical neural foramina (CNF) are considered to be a key factor in nerve root compression and development of cervical radiculopathy. However, to what extent foraminal geometry differs between patients who underwent anterior cervical discectomy and fusion (ACDF) and those who underwent total disc arthroplasty with an artificial disc (AD) during physiological motion is largely unknown. PURPOSE: The objective of this study is to compare CNF dimensions during physiological neck motion between ACDF and AD...
September 4, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28781915/cervical-artificial-disc-extrusion-after-a-paragliding-accident
#18
Tianyi Niu, Haydn Hoffman, Daniel C Lu
BACKGROUND: Cervical total disc replacement (TDR) is an established alternative to anterior cervical discectomy and fusion (ACDF) with excellent long-term outcomes and low failure rates. Cases of implant failure and migration are scarce and primarily limited to several years postoperatively. The authors report a case of anterior extrusion of a C4-C5 ProDisc-C (DePuy Synthes, West Chester, PA, USA) cervical artificial disc (CAD) 14 months after placement due to minor trauma. CASE DESCRIPTION: A 33-year-old female who had undergone C4-C5 CAD implantation presented with neck pain and spasm after experiencing a paragliding accident...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28779946/fertility-disturbances-of-dimethylacetamide-and-glycerol-in-rooster-sperm-diluents-discrimination-among-effects-produced-pre-and-post-freezing-thawing-process
#19
F M K Abouelezz, M A M Sayed, J Santiago-Moreno
With avian sperm cryopreservation protocols, the most widely used cryoprotectants (CPAs) are the glycerol (GLY; in gradual freezing: in-straw freezing method), and the dimethylacetamide (DMA; in pellets by plunging into liquid nitrogen: in-pellet rapid freezing method). Use of both methods results in a small portion of thawed live sperm with lesser fertilizing ability compared with the semen samples immediately after collection. This study was conducted to assess the pre-freezing damage occurring to the sperm due to the interaction with the cryoprotectants (CPAs) GLY (8%) and DMA (5%), as well as the post-freezing damage resulting from both freezing methods Data for each treatment, in fresh and frozen-thawed samples, were compared for sperm motility, fertilizing capacity and sperm-egg penetration holes/germinal disc (SP holes/GD)...
July 29, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28765799/fortifying-the-bone-implant-interface-part-1-an-in-vitro-evaluation-of-3d-printed-and-tps-porous-surfaces
#20
Regina F MacBarb, Derek P Lindsey, Chelsea S Bahney, Shane A Woods, Mark L Wolfe, Scott A Yerby
BACKGROUND: An aging society and concomitant rise in the incidence of impaired bone health have led to the need for advanced osteoconductive spinal implant surfaces that promote greater biological fixation (e.g. for interbody fusion cages, sacroiliac joint fusion implants, and artificial disc replacements). Additive manufacturing, i.e. 3D-printing, may improve bone integration by generating biomimetic spinal implant surfaces that mimic bone morphology. Such surfaces may foster an enhanced cellular response compared to traditional implant surfacing processes...
2017: International Journal of Spine Surgery
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