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Artificial disc

Andreas Reinke, Michael Behr, Alexander Preuss, Jimmy Villard, Bernhard Meyer, Florian Ringel
OBJECT: Total disc replacement (TDR) is typically indicated in young patients with a cervical soft disc herniation. To date, there are few data on the activity level of patients after cervical TDR; in particular, from young patients who are expected to have a high activity level with frequent exercising. The expectation is that returning to active sports after cervical TDR is not restricted. METHODS: Fifty patients were treated with a monosegmental cervical TDR at our department between May 2006 and March 2012...
October 14, 2016: World Neurosurgery
Hang Feng, Xiangyi Fang, Dageng Huang, Chengcheng Yu, Songchuan Zhao, Dingjun Hao
BACKGROUND CONTEXT: Cervical disc arthroplasty has been gradually adopted as an alternative for the treatment of cervical degenerative disease. However, there is a large discrepancy between footprints of currently available cervical disc prostheses and anatomic dimensions of cervical end plates. PURPOSE: This study aimed to accurately and comprehensively quantify the three-dimensional (3D) anatomic morphology of the cervical vertebral end plate and provide a theoretical basis for designing appropriate disc prostheses...
October 3, 2016: Spine Journal: Official Journal of the North American Spine Society
Yixuan Wang, Yun Chen, Hongxu Du, Jingjing Yang, Ke Ming, Meiyun Song, Jiaguo Liu
Duck hepatitis A virus (DHAV) (Picornaviridae) causes an infectious disease in ducks which results in severe losses in duck industry. However, the proper antiviral supportive drugs for this disease have not been discovered. Polysaccharide is the main ingredient of Astragalus that has been demonstrated to directly and indirectly inhibit RNA of viruses replication. In this study, the antiviral activities of Astragalus polysaccharide (APS) and its derivatives against DHAV were evaluated and compared. APS was modified via the sodium trimetaphosphate and sodium tripolyphosphate (STMP-STPP) method and chlorosulfonic acid-pyridine method to obtain its phosphate (pAPS) and sulfate (sAPS), respectively...
October 4, 2016: Experimental Biology and Medicine
Yiqin Duan, Yuhong Liu, Caixia Zhang, Zhe Chen, Shizhu Wen
Liposomes are widely used in drug delivery and gene therapy, and their new role as boundary lubricant in natural/artificial joints has been found in recent years. In this study, the tribological properties of liposomes on titanium alloy (Ti6Al4 V)/UHMWPE interface were studied by a ball-on-disc tribometer. The efficient reduction of friction coefficient and wear on both surfaces under various velocities and loads is found. A multilayer structure of physically adsorbed liposomes on Ti6Al4 V surface was also observed by atomic force microscope (AFM)...
October 10, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
Monish M Maharaj, Ralph J Mobbs, Jarred Hogan, Dong Fang Zhao, Prashanth J Rao, Kevin Phan
BACKGROUND: Surgical approaches are usually required in cases of severe cervical disc disease. The traditional method of anterior cervical disc fusion (ACDF) has been associated with reduced local mobility and increased occurrence of adjacent segment disease. The newer method of anterior cervical disc arthroplasty (ACDA) relies upon artificial discs of various products. Current literature is inconsistent in the comparative performance of these methods with regards to clinical, radiological and patient outcomes...
December 2015: J Spine Surg
Klara Midander, Anneli Julander, Jolinde Kettelarij, Carola Lidén
Metal release from materials immersed in artificial sweat can function as a measure of potential skin exposure. Several artificial sweat models exist that, to various degree, mimic realistic conditions. Study objective was to evaluate metal release from previously examined and well characterized materials in two different artificial sweat solutions; a comprehensive sweat model intended for use within research, based on the composition of human sweat; and the artificial sweat, EN1811, intended for testing compliance with the nickel restriction in REACH...
September 21, 2016: Regulatory Toxicology and Pharmacology: RTP
Elena Provaggi, Julian J H Leong, Deepak M Kalaskar
The latest and fastest-growing innovation in the medical field has been the advent of three-dimensional printing technologies, which have recently seen applications in the production of low-cost, patient-specific medical implants. While a wide range of three-dimensional printing systems has been explored in manufacturing anatomical models and devices for the medical setting, their applications are cutting-edge in the field of spinal surgery. This review aims to provide a comprehensive overview and classification of the current applications of three-dimensional printing technologies in spine care...
September 22, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Jian Song, Yuhong Liu, Zhenhua Liao, Song Wang, Rajnesh Tyagi, Weiqiang Liu
Polyetheretherketone (PEEK) and its composite coatings are believed to be the potential candidates' bio-implant materials. However, these coatings have not yet been used on the surface of titanium-based orthopedics and joint products and very few investigations on the tribological characteristics could be found in the published literature till date. In this study, the wettabilities, composition and micro-hardness were characterized using contact angle measurement, scanning electron microscopy (SEM) and hardness tester...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
Huan Zhang, Meng-Long Zhang, Li-Hong Qiu, Jing-Tao Yu, Fu-Liang Zhan
PURPOSE: To compare the abrasion resistance and flexure strength of three bulk-fill resin composites with an universal nano-hybrid composite resins. METHODS: The specimens were prepared with three kinds of bulk fill composites (SDR , sonicfill, Tetric N-Ceram Bulk Fill) and an universal nano-hybrid composite resins(Herculite Precis). 10 mm in diameter × 2mm in height specimens were prepared for abrasion resistance, while 2 mm in width × 2 mm in depth×25 mm in length specimens were prepared for flexure strength...
June 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
Andrew Turner, Kevin R Solman
Marine litter represents a pervasive environmental problem that poses direct threats to wildlife and habitats. Indirectly, litter can also act as a vehicle for the exposure and bioaccumulation of chemicals that are associated with manufactured or processed solids. In this study, we describe the use of a Niton field-portable-x-ray fluorescence (FP-XRF) spectrometer to determine the content of 17 elements in beached plastics, foams, ropes and painted items. The instrument was used in a 'plastics' mode configured for complex, low density materials, and employed a thickness correction algorithm to account for varying sample depth...
October 1, 2016: Talanta
Rodrigo Cuevas Arenas, Johannes Klingler, Carolyn Vargas, Sandro Keller
Copolymers of styrene and maleic acid (SMA) have gained great attention as alternatives to conventional detergents, as they offer decisive advantages for studying membrane proteins and lipids in vitro. These polymers self-insert into artificial and biological membranes and, at sufficiently high concentrations, solubilise them into disc-shaped nanostructures containing a lipid bilayer core surrounded by a polymer belt. We have used (31)P nuclear magnetic resonance spectroscopy and dynamic light scattering to systematically study the solubilisation of vesicles composed of saturated or unsaturated phospholipids by an SMA copolymer with a 3 : 1 styrene/maleic acid molar ratio at different temperatures...
August 11, 2016: Nanoscale
L Guan, W L Wang, Y Hai, Y Z Liu, X L Chen, L Chen
OBJECTIVE: To evaluate the clinical and radiological outcomes of artificial cervical disc replacement (Prodisc-C), dynamic cervical implant and anterior cervical discectomy and fusion (ACDF) in the treatment of cervical spondylosis. METHOD: From May 2011 to May 2013, a total of 44 cervical spondylosis patients that received cervical disc arthroplasty (Prodisc-C), dynamic cervical implant (DCI) or ACDF were retrospectively reviewed in Orthopedics Department, Beijing Chaoyang Hospital, Capital Medical University...
July 5, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Sheng Shi, Shuang Zheng, Xin-Feng Li, Li-Li Yang, Zu-De Liu, Wen Yuan
OBJECTIVES: Cervical disc arthroplasty (CDA) with Discover prosthesis or anterior cervical discectomy and fusion (ACDF) with Zero-P cage has been widely used in the treatment of cervical spondylotic myelopathy (CSM). However, little is known about the comparison of the 2 zero-profile implants in the treatment of single-level CSM. The aim was to compare the clinical outcomes and radiographic parameters of CDA with Discover prosthesis and ACDF with Zero-P cage for the treatment of single-level CSM...
2016: PloS One
Jun Gue Lee, Hyeun Sung Kim, Chang Il Ju, Seok Won Kim
OBJECTIVE: The anterior approach for C7-T1 disc herniation may be challenging because of obstruction by the manubrium and the narrow operative field. This study aimed to investigate the clinical and neurological outcomes of anterior approach for C7-T1 disc herniation. METHODS: We retrospectively evaluated 13 patients who underwent the anterior approach for C7-T1 disc herniation by a single surgeon within a period of 11 years (2003-2014). The minimum follow-up duration was 6 months...
June 2016: Korean Journal of Spine
Yi Yang, Litai Ma, Hao Liu, Yilian Liu, Ying Hong, Beiyu Wang, Chen Ding, Yuxiao Deng, Yueming Song, Limin Liu
PURPOSE: Compared with anterior cervical discectomy and fusion (ACDF), cervical disc replacement (CDR) has provided satisfactory clinical results. The incidence of post-operative dysphagia between ACDF with a traditional anterior plate and CDR remains controversial. Considering the limited studies and knowledge in this area, a retrospective study focusing on post-operative dysphagia was conducted. METHODS: The Bazaz grading system was used to assess the severity of dysphagia at post-operative intervals including 1 week, 1 month, 3 months, 6 months, 12 months and 24 months respectively...
September 2016: Clinical Neurology and Neurosurgery
Jisoo Choi, Dong-Ah Shin, Sohee Kim
STUDY DESIGN: A three dimensional finite element model of intact lumbar spine was constructed and four surgical finite element models implanted with ball-and-socket artificial discs with four different radii of curvature were compared. OBJECTIVE: To investigate biomechanical effects of the curvature of ball-and-socket artificial disc using finite element analysis. SUMMARY OF BACKGROUND DATA: Total disc replacement (TDR) has been accepted as an alternative treatment due to its advantages over spinal fusion methods in degenerative disc disease...
July 14, 2016: Spine
Pavan S Upadhyayula, John K Yue, Reid Hoshide, Erik Curtis, Joseph D Ciacci
INTRODUCTION: We conducted a retrospective cohort analysis of early outcomes after elective anterior cervical discectomy and fusion (ACDF) vs cervical artificial disc replacement (C-ADR) using the National Surgical Quality Improvement Program database. Risk factors associated with operation time, hospital length of stay, early complications, and discharge destination were studied. METHODS: Adult patients undergoing elective ACDF or C-ADR were abstracted from American College of Surgeons National Surgical Quality Improvement Program years 2011 to 2014...
August 2016: Neurosurgery
Luiz Pimenta, Luis Marchi, Rodrigo Augusto Amaral, Leonardo Oliveira, Joes Nogueira-Neto, Rubens Jensen, Etevaldo Coutinho
INTRODUCTION: The XL-TDR artificial disc is placed by the lateral approach with maintenance of the anterior longitudinal ligament. The purpose of this study was to analyze results of XL-TDR for the treatment of symptomatic degenerative disc disease. METHODS: This is a prospective nonrandomized single-center study. Sixty cases were enrolled (31 males; 66 levels; average age 42.8 years). Eleven of 60 patients (18%) had not completed at least a 5-year follow-up (FUP), and 49 were enrolled (53 levels) in the analysis...
August 2016: Neurosurgery
A M M Giongo, J D Vendramim, S D L Freitas, M F G F Silva
The study was carried out to evaluate the bioactivity of secondary metabolites from Trichilia pallida, Trichilia pallens, and Toona ciliata against fall armyworm Spodoptera frugiperda (J. E. Smith) larvae. The studied compounds included (+/-)-catechins, a triglyceride, and cedrelone isolated from T. ciliata branches, fruits, and stems, respectively; dammaradienol isolated from T. pallida leaves; and scopoletin isolated from T. pallens branches. The compounds' activity was evaluated through ingestion and topic treatment...
July 5, 2016: Neotropical Entomology
Wei Tian, Han Wang, Kai Yan, Xiao Han, Peihao Jin
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To identify the potential preoperative factors and surgical technique factors that are associated with long-term range of motion (ROM) after surgery. Further, this article aimed to guide selection of CADR patients and a fine surgical technique. SUMMARY OF BACKGROUND DATA: Segmental ROM is the most important parameter concerning cervical kinematics after a CADR. There are few researches regarding the influencing factors on postoperative ROM, and consistent results have not yet been reported...
June 28, 2016: Clinical Spine Surgery
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