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https://www.readbyqxmd.com/read/27902945/artificial-cervical-disc-replacement-with-the-prestige-lp-prosthesis-for-the-treatment-of-non-contiguous-2-level-cervical-degenerative-disc-disease-a-minimum-24-month-follow-up
#1
Tingkui Wu, Beiyu Wang, Chen Ding, Yang Meng, Jigang Lou, Yi Yang, Hao Liu
OBJECTIVE: We describe the features of non-contiguous 2-level cervical degenerative disc disease (NCDDD), investigate the safety and feasibility of artificial cervical disc replacement (ACDR) for the treatment of NCDDD, and expect that our study will provide spine surgeons with an alternative procedure for NCDDD. METHODS: Twenty-five patients with NCDDD received ACDR with a Prestige-LP prosthesis. Clinical outcomes were evaluated using the 36-Short Form (SF-36, Mental Component Summary [MCS] and Physical Component Summary [PCS]), Visual Analog Scale (VAS), Japanese Orthopedic Association (JOA), and Neck Disability Index (NDI) scores...
November 17, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27891466/an-in-vitro-evaluation-of-retention-colonization-and-penetration-of-commonly-used-denture-lining-materials-by-candida-albicans
#2
Sushma Krishnamurthy, Rajendra B Hallikerimath
INTRODUCTION: Colonization of the surface by Candida albicans and related Candida species is one of the major concerns of denture lining materials. AIM: We evaluated retention, colonization and penetration of the four denture lining materials namely Molloplast B, Permaflex, GC Soft Liner and Ufi Gel Hard C by Candida albicans. MATERIAL AND METHODS: a) Evaluation of retention: Five test discs of each material with smooth surface on one side and rough on the other were prepared and surface roughness (Ra) was measured with profilometer...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890691/minimum-four-year-subsequent-surgery-rates-of-cervical-disc-replacement-versus-fusion-a-meta-analysis-of-prospective-randomized-clinical-trials
#3
Tingkui Wu, Hao Liu, Beiyu Wang, Yang Meng
: InstructionAnterior cervical discectomy and fusion (ACDF) is a well-accepted surgical management strategy for radiculopathy and/or myelopathy.However, complications sometimes required subsequent surgery at the operated and adjacent levels. Artificial cervical disc replacement (ACDR) has been accepted as the most extensive non-fusion procedure and is designed to preserve motion. However, some specific complications can resultinsubsequent surgery, thus attracting the attention of investigators...
November 24, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27888676/revision-surgery-for-cervical-artificial-disc-surgical-technique-and-clinical-results
#4
J Onken, A Reinke, J Radke, T Finger, S Bayerl, P Vajkoczy, B Meyer
OBJECTIVE: Cervical artificial disc replacement (C-ADR) was developed with the goal of preserving mobility of the cervical segment in patients with degenerative disc disease. So far, little is known about experiences with revision surgery and explantation of C-ADRs. Here, we report our experience with revision the third generation, Galileo-type disc prosthesis from a retrospective study of two institutions. PATIENTS AND METHODS: Between November 2008 and July 2016, 16 patients with prior implantation of C-ADR underwent removal of the Galileo-type disc prosthesis (Signus, Medizintechnik, Germany) due to a call back by industry...
October 31, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27871028/microstructure-analysis-method-for-evaluating-degenerated-intervertebral-disc-tissue
#5
Andrea Friedmann, Felix Goehre, Christopher Ludtka, Thomas Mendel, Hans-Joerg Meisel, Andreas Heilmann, Stefan Schwan
Degeneration of intervertebral disc (IVD) tissue is characterized by several structural changes that result in variations in disc physiology and loss of biomechanical function. The complex process of degeneration exhibits highly intercorrelated biomechanical, biochemical, and cellular interactions. There is currently some understanding of the cellular changes in degenerated intervertebral disc tissue, but microstructural changes and deterioration of the tissue matrix has previously been rarely explored. In this work, sequestered IVD tissue was successfully characterized using histology, light microscopy, and scanning electron microscopy (SEM) to quantitatively evaluate parameters of interest for intervertebral disc degeneration (IDD) such as delamination of the collagenous matrix, cell density, cell size, and extra cellular matrix (ECM) thickness...
October 21, 2016: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/27836574/towards-bioreactor-development-with-physiological-motion-control-and-its-applications
#6
Marcus Stoffel, Wolfgang Willenberg, Marzieh Azarnoosh, Nadine Fuhrmann-Nelles, Bei Zhou, Bernd Markert
In biomedical applications bioreactors are used, which are able to apply mechanical loadings under cultivation conditions on biological tissues. However, complex mechanobiological evolutions, such as the dependency between mechanical properties and cell activity, depend strongly on the applied loading conditions. This requires correct physiological movements and loadings in bioreactors. The aim of the present study is to develop bioreactors, in which native and artificial biological tissues can be cultivated under physiological conditions in knee joints and spinal motion segments...
November 8, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27836147/effect-of-artificial-toothbrushing-and-water-storage-on-the-surface-roughness-and-micromechanical-properties-of-tooth-colored-cad-cam-materials
#7
Simon Flury, Elisabeth Diebold, Anne Peutzfeldt, Adrian Lussi
STATEMENT OF PROBLEM: Because of the different composition of resin-ceramic computer-aided design and computer-aided manufacturing (CAD-CAM) materials, their polishability and their micromechanical properties vary. Moreover, depending on the composition of the materials, their surface roughness and micromechanical properties are likely to change with time. PURPOSE: The purpose of this in vitro study was to investigate the effect of artificial toothbrushing and water storage on the surface roughness (Ra and Rz) and the micromechanical properties, surface hardness (Vickers [VHN]) and indentation modulus (EIT), of 5 different tooth-colored CAD-CAM materials when polished with 2 different polishing systems...
November 14, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27826089/ulf-fernstrom-1915-1985-and-his-contributions-to-the-development-of-artificial-disc-replacements-a-historical-vignette
#8
REVIEW
Christian Fisahn, Brittni Burgess, Joe Iwanaga, Jens R Chapman, Rod J Oskouian, R Shane Tubbs
INTRODUCTION: Artificial disc replacements, which serve the function of separating vertebrae to allow for proper spinal alignment, can help treat debilitating low back pain in patients who have failed other conservative methods of treatment. Ulf Fernstrom was the pioneer of artificial disc replacement, and his contribution in the way of Fernstrom "Balls" dramatically altered spinal surgery and technique by demonstrating the proper technique and implant that should be utilized for areas requiring motion in many planes...
November 5, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27807981/evaluation-of-aesculap-implant-systems-activl-artificial-disc-for-the-treatment-of-degenerative-disc-disease
#9
Daniel Shein, Jennifer Shue, Federico Girardi
A primary cause of chronic low back pain and disability is lumbar degenerative disc disease (DDD). Surgical treatments are available for DDD including fusion or lumbar total disc replacement (TDR). Lumbar TDR is performed as a motion-preserving alternative to lumbar fusion. There are several marketed lumbar TDR devices including the Aesculap Implant Systems activL Artificial Disc, Charité Artificial Disc and the ProDisc-L Total Disc Replacement. Areas covered: Considering the various surgical options by which lumbar DDD can be managed, here we evaluate the biologic and biomechanical benefits and concerns of the Aesculap activL Artificial Disc...
December 2016: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/27751923/return-to-sports-after-cervical-total-disc-replacement
#10
Andreas Reinke, Michael Behr, Alexander Preuss, Jimmy Villard, Bernhard Meyer, Florian Ringel
OBJECT: Total disc replacement (TDR) is typically indicated in young patients with a cervical soft disc herniation. To date, there are few data on the activity level of patients after cervical TDR; in particular, from young patients who are expected to have a high activity level with frequent exercising. The expectation is that returning to active sports after cervical TDR is not restricted. METHODS: Fifty patients were treated with a monosegmental cervical TDR at our department between May 2006 and March 2012...
October 14, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27713104/quantitative-morphometric-study-of-the-subaxial-cervical-vertebrae-end-plate
#11
Hang Feng, Xiangyi Fang, Dageng Huang, Chengcheng Yu, Songchuan Zhao, Dingjun Hao
BACKGROUND CONTEXT: Cervical disc arthroplasty has been gradually adopted as an alternative for the treatment of cervical degenerative disease. However, there is a large discrepancy between footprints of currently available cervical disc prostheses and anatomic dimensions of cervical end plates. PURPOSE: This study aimed to accurately and comprehensively quantify the three-dimensional (3D) anatomic morphology of the cervical vertebral end plate and provide a theoretical basis for designing appropriate disc prostheses...
October 3, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27703041/comparison-of-the-anti-duck-hepatitis-a-virus-activities-of-phosphorylated-and-sulfated-astragalus-polysaccharides
#12
Yixuan Wang, Yun Chen, Hongxu Du, Jingjing Yang, Ke Ming, Meiyun Song, Jiaguo Liu
Duck hepatitis A virus (DHAV) (Picornaviridae) causes an infectious disease in ducks which results in severe losses in duck industry. However, the proper antiviral supportive drugs for this disease have not been discovered. Polysaccharide is the main ingredient of Astragalus that has been demonstrated to directly and indirectly inhibit RNA of viruses replication. In this study, the antiviral activities of Astragalus polysaccharide (APS) and its derivatives against DHAV were evaluated and compared. APS was modified via the sodium trimetaphosphate and sodium tripolyphosphate (STMP-STPP) method and chlorosulfonic acid-pyridine method to obtain its phosphate (pAPS) and sulfate (sAPS), respectively...
October 4, 2016: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27687876/insight-into-the-tribological-behavior-of-liposomes-in-artificial-joints
#13
Yiqin Duan, Yuhong Liu, Caixia Zhang, Zhe Chen, Shizhu Wen
Liposomes are widely used in drug delivery and gene therapy, and their new role as boundary lubricant in natural/artificial joints has been found in recent years. In this study, the tribological properties of liposomes on titanium alloy (Ti6Al4 V)/UHMWPE interface were studied by a ball-on-disc tribometer. The efficient reduction of friction coefficient and wear on both surfaces under various velocities and loads is found. A multilayer structure of physically adsorbed liposomes on Ti6Al4 V surface was also observed by atomic force microscope (AFM)...
October 10, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27683682/anterior-cervical-disc-arthroplasty-acda-versus-anterior-cervical-discectomy-and-fusion-acdf-a-systematic-review-and-meta-analysis
#14
Monish M Maharaj, Ralph J Mobbs, Jarred Hogan, Dong Fang Zhao, Prashanth J Rao, Kevin Phan
BACKGROUND: Surgical approaches are usually required in cases of severe cervical disc disease. The traditional method of anterior cervical disc fusion (ACDF) has been associated with reduced local mobility and increased occurrence of adjacent segment disease. The newer method of anterior cervical disc arthroplasty (ACDA) relies upon artificial discs of various products. Current literature is inconsistent in the comparative performance of these methods with regards to clinical, radiological and patient outcomes...
December 2015: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/27664322/testing-in-artificial-sweat-is-less-more-comparison-of-metal-release-in-two-different-artificial-sweat-solutions
#15
Klara Midander, Anneli Julander, Jolinde Kettelarij, Carola Lidén
Metal release from materials immersed in artificial sweat can function as a measure of potential skin exposure. Several artificial sweat models exist that, to various degree, mimic realistic conditions. Study objective was to evaluate metal release from previously examined and well characterized materials in two different artificial sweat solutions; a comprehensive sweat model intended for use within research, based on the composition of human sweat; and the artificial sweat, EN1811, intended for testing compliance with the nickel restriction in REACH...
November 2016: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/27658427/applications-of-3d-printing-in-the-management-of-severe-spinal-conditions
#16
Elena Provaggi, Julian J H Leong, Deepak M Kalaskar
The latest and fastest-growing innovation in the medical field has been the advent of three-dimensional printing technologies, which have recently seen applications in the production of low-cost, patient-specific medical implants. While a wide range of three-dimensional printing systems has been explored in manufacturing anatomical models and devices for the medical setting, their applications are cutting-edge in the field of spinal surgery. This review aims to provide a comprehensive overview and classification of the current applications of three-dimensional printing technologies in spine care...
September 22, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/27612794/wear-studies-on-zro2-filled-peek-as-coating-bearing-materials-for-artificial-cervical-discs-of-ti6al4v
#17
Jian Song, Yuhong Liu, Zhenhua Liao, Song Wang, Rajnesh Tyagi, Weiqiang Liu
Polyetheretherketone (PEEK) and its composite coatings are believed to be the potential candidates' bio-implant materials. However, these coatings have not yet been used on the surface of titanium-based orthopedics and joint products and very few investigations on the tribological characteristics could be found in the published literature till date. In this study, the wettabilities, composition and micro-hardness were characterized using contact angle measurement, scanning electron microscopy (SEM) and hardness tester...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27609380/-comparison-of-wear-resistance-and-flexural-strength-of-three-kinds-of-bulk-fill-composite-resins
#18
Huan Zhang, Meng-Long Zhang, Li-Hong Qiu, Jing-Tao Yu, Fu-Liang Zhan
PURPOSE: To compare the abrasion resistance and flexure strength of three bulk-fill resin composites with an universal nano-hybrid composite resins. METHODS: The specimens were prepared with three kinds of bulk fill composites (SDR , sonicfill, Tetric N-Ceram Bulk Fill) and an universal nano-hybrid composite resins(Herculite Precis). 10 mm in diameter × 2mm in height specimens were prepared for abrasion resistance, while 2 mm in width × 2 mm in depth×25 mm in length specimens were prepared for flexure strength...
June 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/27474307/analysis-of-the-elemental-composition-of-marine-litter-by-field-portable-xrf
#19
Andrew Turner, Kevin R Solman
Marine litter represents a pervasive environmental problem that poses direct threats to wildlife and habitats. Indirectly, litter can also act as a vehicle for the exposure and bioaccumulation of chemicals that are associated with manufactured or processed solids. In this study, we describe the use of a Niton field-portable-x-ray fluorescence (FP-XRF) spectrometer to determine the content of 17 elements in beached plastics, foams, ropes and painted items. The instrument was used in a 'plastics' mode configured for complex, low density materials, and employed a thickness correction algorithm to account for varying sample depth...
October 1, 2016: Talanta
https://www.readbyqxmd.com/read/27471007/influence-of-lipid-bilayer-properties-on-nanodisc-formation-mediated-by-styrene-maleic-acid-copolymers
#20
Rodrigo Cuevas Arenas, Johannes Klingler, Carolyn Vargas, Sandro Keller
Copolymers of styrene and maleic acid (SMA) have gained great attention as alternatives to conventional detergents, as they offer decisive advantages for studying membrane proteins and lipids in vitro. These polymers self-insert into artificial and biological membranes and, at sufficiently high concentrations, solubilise them into disc-shaped nanostructures containing a lipid bilayer core surrounded by a polymer belt. We have used (31)P nuclear magnetic resonance spectroscopy and dynamic light scattering to systematically study the solubilisation of vesicles composed of saturated or unsaturated phospholipids by an SMA copolymer with a 3 : 1 styrene/maleic acid molar ratio at different temperatures...
August 11, 2016: Nanoscale
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