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https://www.readbyqxmd.com/read/28781915/cervical-artificial-disc-extrusion-after-a-paragliding-accident
#1
Tianyi Niu, Haydn Hoffman, Daniel C Lu
BACKGROUND: Cervical total disc replacement (TDR) is an established alternative to anterior cervical discectomy and fusion (ACDF) with excellent long-term outcomes and low failure rates. Cases of implant failure and migration are scarce and primarily limited to several years postoperatively. The authors report a case of anterior extrusion of a C4-C5 ProDisc-C (DePuy Synthes, West Chester, PA, USA) cervical artificial disc (CAD) 14 months after placement due to minor trauma. CASE DESCRIPTION: A 33-year-old female who had undergone C4-C5 CAD implantation presented with neck pain and spasm after experiencing a paragliding accident...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28779946/fertility-disturbances-of-dimethylacetamide-and-glycerol-in-rooster-sperm-diluents-discrimination-among-effects-produced-pre-and-post-freezing-thawing-process
#2
F M K Abouelezz, M A M Sayed, J Santiago-Moreno
With avian sperm cryopreservation protocols, the most widely used cryoprotectants (CPAs) are the glycerol (GLY; in gradual freezing: in-straw freezing method), and the dimethylacetamide (DMA; in pellets by plunging into liquid nitrogen: in-pellet rapid freezing method). Use of both methods results in a small portion of thawed live sperm with lesser fertilizing ability compared with the semen samples immediately after collection. This study was conducted to assess the pre-freezing damage occurring to the sperm due to the interaction with the cryoprotectants (CPAs) GLY (8%) and DMA (5%), as well as the post-freezing damage resulting from both freezing methods Data for each treatment, in fresh and frozen-thawed samples, were compared for sperm motility, fertilizing capacity and sperm-egg penetration holes/germinal disc (SP holes/GD)...
July 29, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28765799/fortifying-the-bone-implant-interface-part-1-an-in-vitro-evaluation-of-3d-printed-and-tps-porous-surfaces
#3
Regina F MacBarb, Derek P Lindsey, Chelsea S Bahney, Shane A Woods, Mark L Wolfe, Scott A Yerby
BACKGROUND: An aging society and concomitant rise in the incidence of impaired bone health have led to the need for advanced osteoconductive spinal implant surfaces that promote greater biological fixation (e.g. for interbody fusion cages, sacroiliac joint fusion implants, and artificial disc replacements). Additive manufacturing, i.e. 3D-printing, may improve bone integration by generating biomimetic spinal implant surfaces that mimic bone morphology. Such surfaces may foster an enhanced cellular response compared to traditional implant surfacing processes...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28752986/analysis-of-medium-long-term-therapeutic-effect-of-pcm-artificial-cervical-disc-replacement
#4
Haibo Li, Yiping Weng, Dong Zhou, Luming Nong, Nanwei Xu
No abstract text is available yet for this article.
July 28, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28743798/essential-basal-cytonemes-take-up-hedgehog-in-the-drosophila-wing-imaginal-disc
#5
Weitao Chen, Hai Huang, Ryo Hatori, Thomas B Kornberg
Morphogen concentration gradients that extend across developmental fields form by dispersion from source cells. In the Drosophila wing disc, Hedgehog (Hh) produced by posterior compartment cells distributes in a concentration gradient to adjacent cells of the anterior compartment. We monitored Hh:GFP after pulsed expression and analyzed movements and co-localization of Hh, Patched (Ptc) and Smoothened (Smo) proteins tagged with GFP or mCherry and expressed at physiological levels from bacterial artificial chromosome transgenes...
July 25, 2017: Development
https://www.readbyqxmd.com/read/28738168/role-of-age-and-injury-mechanism-in-cervical-spine-injury-tolerance-under-head-contact-loading
#6
Narayan Yoganandan, Sajal Chirvi, Liming Voo, Frank A Pintar, Anjishnu Banerjee
OBJECTIVE: To determine the influence of age on cervical spine tolerance to injury from head contact loading using survival analysis. METHODS: This study analyzed data from previously conducted experiments using Post Mortem Human Subject specimens (PMHS). Group A tests used the upright intact head-cervical column experimental model. The inferior end of the specimen was fixed, head was balanced by a mechanical system, and natural lordosis was removed. Specimens were placed on a testing device via a load cell...
July 24, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28723737/how-to-choose-when-implants-of-adjacent-height-both-fit-the-disc-space-properly-in-single-level-cervical-artificial-disc-replacement
#7
Xin Rong, Jigang Lou, Huibo Li, Yang Meng, Hao Liu
In cervical artificial disc replacement (C-ADR), sometimes we encountered with such cases that implants of adjacent height both fit the target disc space properly. No study was available discussing the choice of implant height and the clinical outcomes under such circumstance. The purpose of this study was to evaluate the impact of different implant heights on the clinical outcomes and radiographic results when the implants of adjacent height both fit the disc space properly. This retrospective study included 34 patients underwent single-level C-ADR at the C5-C6 level at our institution...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28718168/higher-reoperation-rate-following-cervical-disc-replacement-in-a-retrospective-long-term-comparative-study-of-715-patients
#8
Martin Skeppholm, Thomas Henriques, Tycho Tullberg
PURPOSE: To evaluate rates of secondary surgical interventions in a cohort treated with fusion (ACDF), artificial disc replacement (ADR) or a posterior surgical procedure (PP) because of a cervical degenerative pathology. METHODS: 715 patients treated with any primary cervical surgical intervention between the years 2000 and 2010 were retrospectively evaluated regarding frequency of secondary surgery between the years 2000 and 2015, thus giving a follow-up time of minimum 5 years...
July 17, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28717846/effects-of-xylitol-and-sucrose-mint-products-on-streptococcus-mutans-colonization-in-a-dental-simulator-model
#9
Krista M Salli, Ulvi K Gürsoy, Eva M Söderling, Arthur C Ouwehand
Few laboratory methods exist for evaluating the cariogenicity of food ingredients. In this study, a dental simulator was used to determine the effects of commercial sucrose and xylitol mint products on the adherence and planktonic growth of Streptococcus mutans. Solutions (3% w/v) of sucrose, xylitol, sucrose mints, xylitol mints, xylitol with 0.02% peppermint oil (PO), and 0.02% PO alone were used to test the levels of planktonic and adhered S. mutans. A dental simulator with continuous artificial saliva flow, constant temperature, and mixing was used as a test environment and hydroxyapatite (HA) discs were implemented into the model to simulate the tooth surface...
July 17, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28679056/self-healing-dynamic-hydrogel-as-injectable-shock-absorbing-artificial-nucleus-pulposus
#10
Adrián Pérez-San Vicente, Marianna Peroglio, Manuela Ernst, Pablo Casuso, Iraida Loinaz, Hans-Jürgen Grande, Mauro Alini, David Eglin, Damien Dupin
The intervertebral discs (IVDs) provide unique flexibility to the spine and exceptional shock absorbing properties under impact. The inner core of the IVD, the nucleus pulposus (NP) is responsible for this adaptive behavior. Herein, we evaluate an injectable, self-healing dynamic hydrogel (DH) based on gold(I)-thiolate/disulfide (Au-S/SS) exchange as NP replacement in a spine motion segment model. For the first time, we report the application of dynamic covalent hydrogels inside biological tissues. The dynamic exchange between Au-S species and disulfide bonds (SS) resulted in self-healing ability and frequency-dependent stiffness of the hydrogel, which was also confirmed in spine motion segments...
July 19, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28673830/motion-preservation-following-total-lumbar-disc-replacement-at-the-lumbosacral-junction-a-prospective-long-term-clinical-and-radiographic-investigation
#11
Christoph Wuertinger, Raphael Dàgostino Annes, Wolfgang Hitzl, Christoph J Siepe
BACKGROUND CONTEXT: Total lumbar disc replacement (TDR) intends to avoid fusion related negative side effects by means of motion preservation. Despite of their widespread use, the adequate quality and quantity of motion as well as the correlation between radiographic data with the patient's clinical symptomatology remains to be established. Long-term data are lacking in particular. PURPOSE: To perform a clinical and radiographic long-term investigation following TDR with special emphasis on motion preservation assessment and to establish any potential correlation with patient reported outcome parameters...
June 30, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28617725/depth-profile-assessment-of-the-early-phase-deposition-of-lysozyme-on-soft-contact-lens-materials-using-a-novel-in-vitro-eye-model
#12
Han Qiao, Chau-Minh Phan, Hendrik Walther, Lakshman N Subbaraman, Lyndon Jones
OBJECTIVE: To characterize the location of fluorescently labeled lysozyme on commercial contact lenses (CLs) using an in vitro eye model that simulates tear volume, tear flow, air exposure, and mechanical wear. METHODS: One commercially available conventional hydrogel CL material (etafilcon A) and three silicone hydrogel CL materials (balafilcon A, lotrafilcon B, and senofilcon A) were evaluated in this study. The CLs were mounted on the in vitro eye model and exposed to artificial tear fluid containing fluorescein isothiocyanate (FITC)-labeled lysozyme for 2 and 10 hrs...
June 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28614250/the-prevalence-of-heterotopic-ossification-among-patients-after-cervical-artificial-disc-replacement-a-systematic-review-and-meta-analysis
#13
REVIEW
Lingde Kong, Qinghua Ma, Fei Meng, Junming Cao, Kunlun Yu, Yong Shen
BACKGROUND: Prevalence estimates of heterotopic ossification (HO) following cervical artificial disc replacement (ADR) varied widely in previous studies. We conducted a systematic review and meta-analysis to summarize its point prevalence. METHODS: Electronic searches of PubMed, Web of Science, Embase, and Cochrane Library databases were conducted to identify studies that reported prevalence of HO. Definitions of HO and severe HO were based on McAfee grading system...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28597519/feasibility-study-on-robot-assisted-retinal-vascular-bypass-surgery-in-an-ex%C3%A2-vivo-porcine-model
#14
Yi Qi Chen, Ji Wei Tao, Liang Li, Jian Bo Mao, Chen Ting Zhu, Ji Meng Lao, Yang Yang, Li-Jun Shen
PURPOSE: To describe a new robot-assisted surgical system for retinal vascular bypass surgery (RVBS) and to compare the success rate with freehand RVBS. METHODS: A robot-assisted system for retinal microsurgery was constructed to include two independent robotic arms. A 23-gauge light probe and an intraocular forceps were affixed to the arm end effectors to perform the intraocular manipulation. Harvested porcine eyes were introduced to be established animal models of closed-sky eyeballs after that pars plana vitrectomy using temporary keratoprosthesis was performed by a skilful surgeon...
June 9, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28597366/finite-element-model-predicts-the-biomechanical-performance-of-cervical-disc-replacement-and-fusion-hybrid-surgery-with-various-geometry-of-ball-and-socket-artificial-disc
#15
Yang Li, Guy R Fogel, Zhenhua Liao, Weiqiang Liu
PURPOSE: Few finite element studies have investigated changes in cervical biomechanics with various prosthesis design parameters using hybrid surgery (HS), and none have investigated those combined different HS strategies. The aim of our study was to investigate the effect of ball-and-socket prosthesis geometry on the biomechanical performance of the cervical spine combined with two HS constructs. METHODS: Two HS strategies were conducted: (1) ACDF at C4-C5 and anterior cervical disc replacement (ACDR) at C5-C6 (ACDF/ACDR), and (2) ACDR/ACDF...
August 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28582418/an-in-vivo-comparison-study-in-goats-for-a-novel-motion-preserving-cervical-joint-system
#16
Jie Qin, Chenguang Zhao, Dong Wang, Bo Zhao, Jun Dong, Haopeng Li, Rongxia Sang, Shuang Wang, Jiao Fu, Rangrang Kong, Xijing He
Cervical degenerative disease is one of the most common spinal disorders worldwide, especially in older people. Anterior cervical corpectomy and fusion (ACCF) is a useful method for the surgical treatment of multi-level cervical degenerative disease. Anterior cervical disc replacement (ACDR) is considered as an alternative surgical method. However, both methods have drawbacks, particularly the neck motion decrease observed after arthrodesis, and arthroplasty should only be performed on patients presenting with cervical disc disease but without any vertebral body disease...
2017: PloS One
https://www.readbyqxmd.com/read/28574978/adjacent-segment-degeneration-following-anterior-cervical-discectomy-and-fusion-versus-the-bryan-cervical-disc-arthroplasty
#17
Suo-Zhou Yan, Jun Di, Yong Shen
BACKGROUND Anterior cervical discectomy and fusion (ACDF) is an established treatment for degenerative disease of the cervical disc, but adjacent segment degeneration or instability may develop long term. The aim of this study was to investigate the risk factors for adjacent segment degeneration following ACDF compared with the use of the Bryan artificial disc for cervical disc arthroplasty (CDA). MATERIAL AND METHODS A prospective comparative study included 93 patients who underwent ACDF or CDA with the Bryan artificial cervical disc between 2002 and 2004, and who had more than eight years of follow-up...
June 2, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28574094/effect-of-storage-medium-and-aging-duration-on-mechanical-properties-of-self-adhesive-resin-based-cements
#18
Anja Liebermann, Nicoleta Ilie, Malgorzata Roos, Bogna Stawarczyk
BACKGROUND: The aim of this study was to investigate the effects of storage medium and aging duration on Martens hardness (HM) and indentation modulus (EIT) of self-adhesive resin-based cements (SARCs). METHODS: A total of 416 discs were fabricated from 8 SARCs (n = 52 per SARC): (i) BeautyCem (BEA), (ii) Bifix SE (BIF), (iii) Clearfil SA Cement Automix (CLE), (iv) RelyX Unicem2 Automix (RXU), (v) SeT (SET), (vi) SmartCem 2 (SMC), (vii) SoloCem (SOC) and (viii) SpeedCEM (SPC)...
May 24, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28571254/quantitative-analysis-of-remineralization-of-artificial-carious-lesions-with-commercially-available-newer-remineralizing-agents-using-sem-edx-in-vitro-study
#19
Zaheer Ahmed Shaik, Tanikonda Rambabu, Girija Sajjan, Madhu Varma, Kalyan Satish, Vijayalakshmi Bhupathi Raju, Sirisha Ganguru, Nagalkashmi Ventrapati
INTRODUCTION: The basic principle of remineralization is by advocating a biological or non-invasive approach rather than the surgical approach for early enamel lesions. There are relatively newer products available for remineralization, latest being the resin-infiltration technique, commercially available as Icon. AIM: The aim of the study was to evaluate the remineralizing potential of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP), Vantej and Icon by the quantitative evaluation of mineral gain...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28536978/a-6-dof-parallel-bone-grinding-robot-for-cervical-disc-replacement-surgery
#20
Heqiang Tian, Chenchen Wang, Xiaoqing Dang, Lining Sun
Artificial cervical disc replacement surgery has become an effective and main treatment method for cervical disease, which has become a more common and serious problem for people with sedentary work. To improve cervical disc replacement surgery significantly, a 6-DOF parallel bone-grinding robot is developed for cervical bone-grinding by image navigation and surgical plan. The bone-grinding robot including mechanical design and low level control is designed. The bone-grinding robot navigation is realized by optical positioning with spatial registration coordinate system defined...
May 24, 2017: Medical & Biological Engineering & Computing
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