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https://www.readbyqxmd.com/read/28530314/-presentation-of-ocular-problems-among-displaced-persons-from-sudan-and-eritrea-at-the-tel-aviv-medical-center
#1
Roy Schwartz, Michaella Goldstein, Anat Loewenstein, Adiel Barak
INTRODUCTION: Illegal immigration from Africa to Israel expanded in recent years, bringing illegal immigrants, mostly from Eritrea and Sudan. No data regarding the ophthalmic conditions of this population was previously published. AIMS: To delineate reasons for ophthalmologic emergency room visits and hospitalizations in the ophthalmology department at a tertiary center in Tel Aviv, Israel. METHODS: In this retrospective study we reviewed the records of patients of Eritrean and Sudanese origin arriving at the ophthalmic emergency room at the Tel Aviv Sourasky Medical Center between June 2012 and August 2012 and hospitalized in the ophthalmology ward between August 2011 and August 2012...
January 2017: Harefuah
https://www.readbyqxmd.com/read/28525756/immunization-elicited-broadly-protective-antibody-reveals-ebolavirus-fusion-loop-as-a-site-of-vulnerability
#2
Xuelian Zhao, Katie A Howell, Shihua He, Jennifer M Brannan, Anna Z Wec, Edgar Davidson, Hannah L Turner, Chi-I Chiang, Lin Lei, J Maximilian Fels, Hong Vu, Sergey Shulenin, Ashley N Turonis, Ana I Kuehne, Guodong Liu, Mi Ta, Yimeng Wang, Christopher Sundling, Yongli Xiao, Jennifer S Spence, Benjamin J Doranz, Frederick W Holtsberg, Andrew B Ward, Kartik Chandran, John M Dye, Xiangguo Qiu, Yuxing Li, M Javad Aman
While neutralizing antibodies are highly effective against ebolavirus infections, current experimental ebolavirus vaccines primarily elicit species-specific antibody responses. Here, we describe an immunization-elicited macaque antibody (CA45) that clamps the internal fusion loop with the N terminus of the ebolavirus glycoproteins (GPs) and potently neutralizes Ebola, Sudan, Bundibugyo, and Reston viruses. CA45, alone or in combination with an antibody that blocks receptor binding, provided full protection against all pathogenic ebolaviruses in mice, guinea pigs, and ferrets...
May 18, 2017: Cell
https://www.readbyqxmd.com/read/28523485/report-of-mesocaval-shunt-in-the-management-of-variceal-hemorrhage-following-gastric-bypass-surgery
#3
Anurag Shrimal, Ranjan Sudan, Gaurav Chaubal, Ahmad Zaaroura, Kitza Williams, Kadiyala Ravindra
Gastrointestinal bleeding following Roux-en- Y gastric bypass (RYGB) is rare. We report an unusual cause of upper gastrointestinal bleeding following RYGB that was complicated by porto- splenic vein thrombosis. A 35- year- old woman was successfully treated by mesocaval surgical shunt for recurrent variceal hemorrhage in the excluded stomach following RYGB.
May 18, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28523007/transcriptomic-identification-of-drought-related-genes-and-ssr-markers-in-sudan-grass-based-on-rna-seq
#4
Yongqun Zhu, Xia Wang, Linkai Huang, Chaowen Lin, Xinquan Zhang, Wenzhi Xu, Jianhua Peng, Zhou Li, Haidong Yan, Fuxiang Luo, Xie Wang, Li Yao, Dandan Peng
Sudan grass (Sorghum sudanense) is an annual warm-season gramineous forage grass that is widely used as pasture, hay, and silage. However, drought stress severely impacts its yield, and there is limited information about the mechanisms of drought tolerance in Sudan grass. In this study, we used next-generation sequencing to identify differentially expressed genes (DEGs) in the Sudan grass variety Wulate No.1, and we developed simple sequence repeat (SSR) markers associated with drought stress. From 852,543,826 raw reads, nearly 816,854,366 clean reads were identified and used for analysis...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28521827/antioxidant-activity-acetylcholinesterase-inhibitory-potential-and-phytochemical-analysis-of-sarcocephalus-latifolius-sm-bark-used-in-traditional-medicine-in-sudan
#5
Alsiddig Osama, Sufyan Awadelkarim, Amna Ali
BACKGROUND: Sarcocephalus latifolius is used as a traditional medicine for curing many diseases in Sudan. The main objective of the current study was to determine the antioxidant activity and acetylcholinesterase inhibition (AChEI) of S. latifolius, and to estimate its total phenolic and flavonoid contents. METHODS: Antioxidant activity of the tested plant extracts was carried out by determining their ability to scavenge the 2,2-diphenyl-1-picryl hydrazyl (DPPH) free radical...
May 18, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28508324/impact-of-clinical-pharmacist-intervention-in-anticoagulation-clinic-in-sudan
#6
Nahid Osman Ahmed, Bashier Osman, Yassein Mohamed Abdelhai, Tariq Muhammed Hashim El-Hadiyah
Background Many trials have compared anticoagulation management provided by a pharmacist led anticoagulation clinic versus usual physician care showing the role for clinical pharmacist in the management of anticoagulant therapy, and demonstrating excellent outcomes. In Sudan, there is no published research evaluating the role of pharmacist in providing pharmaceutical care for patients taking warfarin. Objective The objective of the study is to assess the role of clinical pharmacist intervention in warfarin patients compared to usual medical care...
May 15, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28504464/skeletal-maturity-of-the-hand-in-an-east-african-group-from-sudan
#7
Fadil Elamin, Nihal Abdelazeem, Ahmed Elamin, Duaa Saif, Helen M Liversidge
OBJECTIVES: Studies of skeletal maturity from Africa indicate a delay, reflected in a negative relative skeletal age (RSA). This study aims to evaluate the influence of age, socioeconomic status (SES) and nutritional status on skeletal maturation in a large sample of children from North Sudan. MATERIALS: The sample consisted 665 males and 1018 females from 3-25 years from Khartoum. Height, weight, age of menarche and, SES were recorded of patients attending for dental treatment...
May 15, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28495200/genotyping-of-theileria-lestoquardi-from-sheep-and-goats-in-sudan-to-support-control-of-malignant-ovine-theileriosis
#8
A M Ali, D A Salih, M N Njahira, S K Hassan, A M El Hussein, Z Liu, H Yin, R Pelle, R A Skilton
Theileriosis, caused by parasitic protozoa of the genus Theileria parasites, are among the major tick-borne diseases of ruminant livestock. The largest economic losses are attributed in particular to those caused by the leukoproliferative species of Theileria: T. parva, T. annulata and T. lestoquardi. Theileria lestoquardi is transmitted by Hyalomma ticks and causes malignant ovine theileriosis (MOT), a disease that is particularly prevalent in Sudan. The disease is considered of a high economic importance in Sudan, where export of sheep is a major component of the national economy...
May 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28494701/spindle-cell-lipoma-in-dogs
#9
Giancarlo Avallone, Valeria Pellegrino, Luisa V Muscatello, Giuseppe Sarli, Paola Roccabianca
Spindle cell lipoma (SCL) is a benign neoplasm of the adipose tissue that may resemble an undifferentiated soft tissue sarcoma (STS). This report describes the histopathological features of 6 SCLs in dogs. All SCLs were located in the subcutis and were composed of bland, occasionally vacuolated spindle cells intermixed with ropey collagen and myxoid matrix. Sudan IV stain performed in 1 case demonstrated the lipid content of vacuoles. Mature adipocytes represented less than 10% of the neoplasm in 3 cases and were absent in the remaining 3...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28487659/optimizing-immunostaining-of-enamel-matrix-application-of-sudan-black-b-and-minimization-of-false-positives-from-normal-sera-and-iggs
#10
Xu Yang, Alexander J Vidunas, Elia Beniash
Non-specific fluorescence from demineralized enamel matrix can significantly compromise the immunofluorescence studies and lead to false positives. Our goal was to assess degrees of non-specific binding under different conditions and try to optimize procedures for immunofluorescence studies of forming enamel. Firstly, we compared two methods for background fluorescence elimination, i.e., sodium borohydride and Sudan Black B treatments. The results demonstrated that Sudan Black B is far superior to sodium borohydride in reducing the background fluorescence in dental tissues...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28485694/childhood-pneumonia-diagnostics-community-health-workers-and-national-stakeholders-differing-perspectives-of-new-and-existing-aids
#11
Hollie Spence, Kevin Baker, Alexandra Wharton-Smith, Akasiima Mucunguzi, Lena Matata, Tedila Habte, Diana Nanyumba, Anteneh Sebsibe, Thol Thany, Karin Källander
BACKGROUND: Pneumonia heavily contributes to global under-five mortality. Many countries use community case management to detect and treat childhood pneumonia. Community health workers (CHWs) have limited tools to help them assess signs of pneumonia. New respiratory rate (RR) counting devices and pulse oximeters are being considered for this purpose. OBJECTIVE: To explore perspectives of CHWs and national stakeholders regarding the potential usability and scalability of seven devices to aid community assessment of pneumonia signs...
2017: Global Health Action
https://www.readbyqxmd.com/read/28470406/targeting-mannose-receptor-expression-on-macrophages-in-atherosclerotic-plaques-of-apolipoprotein-e-knockout-mice-using-111-in-tilmanocept
#12
Zohreh Varasteh, Fabien Hyafil, Nadège Anizan, Devy Diallo, Rachida Aid-Launais, Sarajo Mohanta, Yuanfang Li, Miriam Braeuer, Katja Steiger, Jonathan Vigne, Zhengtao Qin, Stephan G Nekolla, Jean-Etienne Fabre, Yvonne Döring, Dominique Le Guludec, Andreas Habenicht, David R Vera, Markus Schwaiger
BACKGROUND: Atherosclerotic plaque phenotypes are classified based on the extent of macrophage infiltration into the lesions, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR) is over-expressed in activated macrophages. Tilmanocept is a tracer that targets MR and is approved in Europe and the USA for the detection of sentinel lymph nodes. In this study, our aim was to evaluate the potential of (111)In-labelled tilmanocept for the detection of MR-positive macrophages in atherosclerotic plaques of apolipoprotein E-knockout (ApoE-KO) mouse model...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28469316/cervical-cytopathological-changes-among-women-with-vaginal-discharge-attending-teaching-hospital
#13
Magdi M Salih, Fatma Tage El Sir AlHag, Mohammed Ahmed Khalifa, Abdulla H El Nabi
AIMS: To find cytology changes among women attending obstetrics and gynaecology clinic with complaints of vaginal discharges. SETTINGS AND DESIGN: This descriptive hospital-based cytological study was conducted at the outpatient clinic of the obstetrics and gynaecology department. MATERIALS AND METHODS: Two hundred women with complaints of vaginal discharge were selected. Their detailed histories were documented on a special request form. Pap smears were then obtained and sent for cytological examination to the cytopathology department...
April 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28467674/evaluation-of-a-mixed-anionic-nonionic-surfactant-modified-eggshell-membrane-as-an-advantageous-adsorbent-for-the-solid-phase-extraction-of-sudan-i-iv-as-model-analytes
#14
Ying Li, Anyi Wang, Yunfei Bai, Shiping Wang
The coadsorption of mixed anionic-nonionic surfactants, sodium dodecylbenzenesulfonate with Triton X-100, on the surface of eggshell membrane was investigated based on adsorption isotherms to improve the solid-phase extraction performance of eggshell membrane towards organic contaminants. Results showed that even though excess Triton X-100 might inhibit the adsorption of sodium dodecylbenzenesulfonate, a low dosage of Triton X-100 can significantly improve sodium dodecylbenzenesulfonate modification and enhance the extraction efficiency of eggshell membrane from 73...
May 3, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28466035/analysis-of-ebola-virus-polymerase-domains-to-find-strain-specific-differences-and-to-gain-insight-on-their-pathogenicity
#15
Seema Patel, Snigdha Patel
Ebola virus, a member of the family Filoviridae has caused immense morbidity and mortality in recent times, especially in West Africa. The infection characterized by chills, fever, diarrhea, and myalgia can progress to hemorrhage and death. Hence, it is a high priority area to better understand its biology in order to expedite vaccine development pipelines. In this regard, this study analyzes the domains in RNA polymerase of fifteen publicly-available Ebola isolates belonging to three strains (Zaire, Sudan and Reston)...
September 2016: Virusdisease
https://www.readbyqxmd.com/read/28465098/flex-nucleoside-analogues-novel-therapeutics-against-filoviruses
#16
Mary K Yates, Mithun R Raje, Payel Chatterjee, Christina F Spiropoulou, Sina Bavari, Mike Flint, Veronica Soloveva, Katherine L Seley-Radtke
Fleximers, a novel type of flexible nucleoside that have garnered attention due to their unprecedented activity against human coronaviruses, have now exhibited highly promising levels of activity against filoviruses. The Flex-nucleoside was the most potent against recombinant Ebola virus in Huh7 cells with an EC50=2μM, while the McGuigan prodrug was most active against Sudan virus-infected HeLa cells with an EC50 of 7μM.
April 22, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28458866/a-live-term-intra-abdominal-pregnancy-in-a-field-hospital-a-case-report
#17
Shadi Abdelrahman, Matthew Deeter, Anitha Muthusami, Trine G Peterson, Leen Wackenier
Abdominal pregnancy is a rare form of ectopic pregnancy with high morbidity and mortality for both the mother and the fetus. Diagnosis can be challenging, especially in a resource-limited setting. We report a case of abdominal pregnancy that presented to Médecins Sans Frontières field hospital in Agok, South Sudan, with abdominal pain. Examination revealed a term pregnancy and a live fetus in transverse lie. The diagnosis of abdominal pregnancy was made intraoperatively, with successful management and delivery of a healthy baby...
March 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28451049/sero-prevalence-for-hepatitis-b-virus-among-pregnant-women-attending-antenatal-clinic-in-juba-teaching-hospital-republic-of-south-sudan
#18
Anthony Laku Stephen Kirbak, Zipporah Ng'ang'a, Jared Omolo, Hakim Idris, Abdulmumini Usman, William Baguma Mbabazi
INTRODUCTION: Hepatitis B virus infection is a major public health problem worldwide and in Africa. This would be the first ever documented study on epidemiology of Hepatitis B infections in the newly formed Republic of South Sudan. This study was designed to estimate the sero-prevalence of Hepatitis B virus infection amongst pregnant women attending antenatal services in Juba. METHODS: A cross-sectional study was conducted among pregnant women attending antenatal clinic services in Juba Teaching Hospital, in the period between December 2012 and March 2013...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28451021/depression-among-hiv-aids-sudanese-patients-a-cross-sectional-analytic-study
#19
Abdulateef Elbadawi, Hyder Mirghani
INTRODUCTION: Depression and HIV/AIDS are common morbid health problems; the relationship is bidirectional exacerbating each other with deleterious consequences. There are limited studies on this topic in Sudan. In this study, we investigated depression among HIV/AIDS in Sudan. METHODS: A cross-sectional analytic study was conducted among 362 HIV/AIDS patients from three centers in Khartoum, Sudan. Data were collected by the Hospital Depression and Anxiety (HADS) questionnaire...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28450836/renal-denervation-promotes-atherosclerosis-in-hypertensive-apolipoprotein-e-deficient-mice-infused-with-angiotensin-ii
#20
Yutang Wang, Tam N Dinh, Alexander Nield, Smriti M Krishna, Kate Denton, Jonathan Golledge
Objective: To determine the effect of renal denervation (RDN) on the severity of atherosclerosis and aortic aneurysm in hypertensive mice. Methods: Hypertension, atherosclerosis and aortic aneurysm were induced by subcutaneous infusion of angiotensin II (1 μg/kg/min) for 28 days in apolipoprotein E-deficient mice. RDN was conducted using combined surgical and local chemical denervation. The norepinephrine concentration in the kidney was measured by high-performance liquid chromatography. Blood pressure was measured by the tail-cuff method...
2017: Frontiers in Physiology
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