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https://www.readbyqxmd.com/read/28207905/the-one-health-approach-to-identify-knowledge-attitudes-and-practices-that-affect-community-involvement-in-the-control-of-rift-valley-fever-outbreaks
#1
Osama Ahmed Hassan, Hippolyte Affognon, Joacim Rocklöv, Peter Mburu, Rosemary Sang, Clas Ahlm, Magnus Evander
Rift Valley fever (RVF) is a viral mosquito-borne disease with the potential for global expansion, causes hemorrhagic fever, and has a high case fatality rate in young animals and in humans. Using a cross-sectional community-based study design, we investigated the knowledge, attitudes and practices of people living in small village in Sudan with respect to RVF outbreaks. A special One Health questionnaire was developed to compile data from 235 heads of household concerning their knowledge, attitudes, and practices with regard to controlling RVF...
February 16, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28197041/authors-reply
#2
Madhu Sudan Agrawal, Dilip Kumar Mishra
No abstract text is available yet for this article.
January 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28197030/superperc-a-new-technique-in-minimally-invasive-percutaneous-nephrolithotomy
#3
Kaushik Shah, Madhu Sudan Agrawal, Dilip Kumar Mishra
INTRODUCTION: Percutaneous nephrolithotomy (PCNL) has undergone significant changes in recent years in the quest for improving efficacy and reducing morbidity. Newer minimally-invasive modalities of PCNL such as mini-PCNL, ultra-mini PCNL, and micro-PCNL have evolved with advancement in optics and technology. However, with these newer advancements, migration of small fragments produced with laser lithotripsy remains a concern, which may result in incomplete stone clearance. We describe a new technique of PCNL termed "Superperc", that utilizes suction to remove all the fragments and maintain one-way flow...
January 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28196336/regression-of-atherosclerosis-with-apple-procyanidins-by-activating-the-atp-binding-cassette-subfamily-a-member-1-in-a-rabbit-model
#4
Liang Wang, Toshio Fumoto, Saeko Masumoto, Toshihiko Shoji, Tomisato Miura, Masato Naraoka, Naoya Matsuda, Tadaatsu Imaizumi, Hiroki Ohkuma
BACKGROUND AND AIMS: Apple polyphenol contains abundant procyanidins, which have been associated with an anti-atherosclerosis and cholesterol-lowering effect. The aim of this study was to investigate whether apple procyanidins (APCs) feature therapeutic efficacy in terms of regressing atherosclerosis and whether this efficacy is due to mechanisms other than a cholesterol-lowering effect. METHODS: After eight weeks on an atherogenic diet, rabbits were given a normal diet for another eight weeks to normalize the increased serum lipids level...
January 27, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28193398/incidence-of-invasive-salmonella-disease-in-sub-saharan-africa-a-multicentre-population-based-surveillance-study
#5
Florian Marks, Vera von Kalckreuth, Peter Aaby, Yaw Adu-Sarkodie, Muna Ahmed El Tayeb, Mohammad Ali, Abraham Aseffa, Stephen Baker, Holly M Biggs, Morten Bjerregaard-Andersen, Robert F Breiman, James I Campbell, Leonard Cosmas, John A Crump, Ligia Maria Cruz Espinoza, Jessica Fung Deerin, Denise Myriam Dekker, Barry S Fields, Nagla Gasmelseed, Julian T Hertz, Nguyen Van Minh Hoang, Justin Im, Anna Jaeger, Hyon Jin Jeon, Leon Parfait Kabore, Karen H Keddy, Frank Konings, Ralf Krumkamp, Benedikt Ley, Sandra Valborg Løfberg, Jürgen May, Christian G Meyer, Eric D Mintz, Joel M Montgomery, Aissatou Ahmet Niang, Chelsea Nichols, Beatrice Olack, Gi Deok Pak, Ursula Panzner, Jin Kyung Park, Se Eun Park, Henintsoa Rabezanahary, Raphaël Rakotozandrindrainy, Tiana Mirana Raminosoa, Tsiriniaina Jean Luco Razafindrabe, Emmanuel Sampo, Heidi Schütt-Gerowitt, Amy Gassama Sow, Nimako Sarpong, Hye Jin Seo, Arvinda Sooka, Abdramane Bassiahi Soura, Adama Tall, Mekonnen Teferi, Kamala Thriemer, Michelle R Warren, Biruk Yeshitela, John D Clemens, Thomas F Wierzba
BACKGROUND: Available incidence data for invasive salmonella disease in sub-Saharan Africa are scarce. Standardised, multicountry data are required to better understand the nature and burden of disease in Africa. We aimed to measure the adjusted incidence estimates of typhoid fever and invasive non-typhoidal salmonella (iNTS) disease in sub-Saharan Africa, and the antimicrobial susceptibility profiles of the causative agents. METHODS: We established a systematic, standardised surveillance of blood culture-based febrile illness in 13 African sentinel sites with previous reports of typhoid fever: Burkina Faso (two sites), Ethiopia, Ghana, Guinea-Bissau, Kenya, Madagascar (two sites), Senegal, South Africa, Sudan, and Tanzania (two sites)...
March 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28191742/a-tethered-ru-s-complex-with-an-axial-chiral-thiolate-ligand-for-cooperative-si-h-bond-activation-application-to-enantioselective-imine-reduction
#6
Simon Wübbolt, Modhu Sudan Maji, Elisabeth Irran, Martin Oestreich
An axial chiral version of the 2,6-dimesitylphenyl group attached to sulfur is reported. Its multistep preparation starts from (S)-binol, and the thiol group is established by a racemization-free thermal Newman-Kwart rearrangement. The new chiral thiolate ligand decorated with one mesityl group is used in the synthesis of a tethered ruthenium chloride complex. Its spectroscopic characterization revealed solvent-dependent epimerization at the ruthenium center. The major diastereomer is crystallographically characterized...
February 13, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28186591/-application-of-recombinant-gp%C3%A2-a-combined-luminex-beads-for-the-detection-of-hpa-1a-antibody
#7
Sudan Tao, Ying Liu, Yanming He, Yanling Ying, Ji He, Faming Zhu
OBJECTIVE: To generate recombinant GPⅢa as an alternative source for HPA-1a antigen and combine it with Luminex xMAP beads for the detection of HPA-1a-specific alloantibody. METHODS: The full coding region of ITGB3 gene was amplified and ligated with pcDNA3.1. The recombinant plasmid was transfected into CHO cells, and those with stable expression were screened with G418. Expressed protein was identified and coupled with Luminex xMAP beads, which were then reacted with sera samples...
February 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28185406/detecting-senescence-a-new-method-for-an-old-pigment
#8
Hanna Salmonowicz, João F Passos
Cellular senescence is a state of irreversible cell cycle arrest induced by different types of cellular stresses. The field of senescence has made significant advances in the understanding of many of the mechanisms governing this phenomenon; however, a universal biomarker that unambiguously distinguishes senescent from proliferating cells has not been found. In this issue of Aging Cell, Evangelou and colleagues developed a sensitive method for identification of senescent cells in different types of biological material based on the detection of lipofuscin using an analogue of Sudan Black B (SBB) histochemical dye coupled with biotin, which they named GL13...
February 9, 2017: Aging Cell
https://www.readbyqxmd.com/read/28183739/association-of-sociodemographic-and-household-characteristics-with-non-fatal-burns-among-children-under-the-age-of-10%C3%A2-years-in-sudan-an-exploratory-secondary-analysis-of-the-sudan-household-health-survey-2010
#9
Safa Abdalla, Muna Abdel Aziz, Igbal Basheir
BACKGROUND: Globally, children have the highest mortality rates from fire-related burns. Sudan is no exception, but there had been no prior investigations of potentially preventable risk factors. We undertook this analysis to investigate the role of various sociodemographic and household factors. METHODS: We used Sudan Household Health Survey 2010 data from a national stratified multistage cluster sample of 15 000 households. The dependent variable was whether the child had a non-fatal burn in the 12 months preceding the survey, based on the most recent injury...
February 9, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28182726/spatial-patterns-of-multidrug-resistant-tuberculosis-and-relationships-to-socio-economic-demographic-and-household-factors-in-northwest-ethiopia
#10
Kefyalew Addis Alene, Kerri Viney, Emma S McBryde, Archie C A Clements
BACKGROUND: Understanding the geographical distribution of multidrug-resistant tuberculosis (MDR-TB) in high TB burden countries such as Ethiopia is crucial for effective control of TB epidemics in these countries, and thus globally. We present the first spatial analysis of multidrug resistant tuberculosis, and its relationship to socio-economic, demographic and household factors in northwest Ethiopia. METHODS: An ecological study was conducted using data on patients diagnosed with MDR-TB at the University of Gondar Hospital MDR-TB treatment centre, for the period 2010 to 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28182652/nakalanga-syndrome-clinical-characteristics-potential-causes-and-its-relationship-with-recently-described-nodding-syndrome
#11
REVIEW
Kathrin Föger, Gina Gora-Stahlberg, James Sejvar, Emilio Ovuga, Louise Jilek-Aall, Erich Schmutzhard, Christoph Kaiser, Andrea S Winkler
Nakalanga syndrome is a condition that was described in Uganda and various other African countries decades ago. Its features include growth retardation, physical deformities, endocrine dysfunction, mental impairment, and epilepsy, amongst others. Its cause remains obscure. Nodding syndrome is a neurological disorder with some features in common with Nakalanga syndrome, which has been described mainly in Uganda, South Sudan, and Tanzania. It has been considered an encephalopathy affecting children who, besides head nodding attacks, can also present with stunted growth, delayed puberty, and mental impairment, amongst other symptoms...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28180226/facile-fabrication-of-sudan-red-particle-microcapsules-by-a-polymerizable-gemini-surfactant-and-molecular-assembly-mechanisms
#12
Yaqian Wu, Haike Yan, Xuefeng Shi, Jinben Wang
An efficient method was developed to encapsulate water insoluble organic particles of Sudan red III (SR) in aqueous suspensions by using a polymerizable cationic gemini surfactant, 1,3-bis(N,N-dimethyl-N-cetylammonium)-2-(propylacrylate dibromide) (AGC16). The AGC16 coated SR microcapsules (AGC16@SR) were prepared by absorption of AGC16 on the surface of SR, followed by in situ homopolymerization (PAGC16). Several measurements, including transmission and scanning electron microscopy, isothermal titration calorimetry, zeta potential, electron paramagnetic resonance and small angle X-ray scattering, were performed to determine the adsorption amount of AGC16, and the layer structures and the molecular assembly mechanism in the AGC16@SR and PAGC16@SR systems, respectively...
February 9, 2017: Soft Matter
https://www.readbyqxmd.com/read/28179495/a-new-immunomodulatory-role-for-peroxisomes-in-macrophages-activated-by-the-tlr4-ligand-lipopolysaccharide
#13
Vijith Vijayan, Tumpara Srinu, Srikanth Karnati, Vannuruswamy Garikapati, Monika Linke, Lilit Kamalyan, Srihari Reddy Mali, Kritika Sudan, Andreas Kollas, Tobias Schmid, Sabine Schulz, Bernhard Spengler, Thomas Weichhart, Stephan Immenschuh, Eveline Baumgart-Vogt
Peroxisomes are proposed to play an important role in the regulation of systemic inflammation; however, the functional role of these organelles in inflammatory responses of myeloid immune cells is largely unknown. In this article, we demonstrate that the nonclassical peroxisome proliferator 4-phenyl butyric acid is an efficient inducer of peroxisomes in various models of murine macrophages, such as primary alveolar and peritoneal macrophages and the macrophage cell line RAW264.7, but not in primary bone marrow-derived macrophages...
February 8, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28178973/mortality-from-tetanus-between-1990-and-2015-findings-from-the-global-burden-of-disease-study-2015
#14
Hmwe H Kyu, John Everett Mumford, Jeffrey D Stanaway, Ryan M Barber, Jamie R Hancock, Theo Vos, Christopher J L Murray, Mohsen Naghavi
BACKGROUND: Although preventable, tetanus still claims tens of thousands of deaths each year. The patterns and distribution of mortality from tetanus have not been well characterized. We identified the global, regional, and national levels and trends of mortality from neonatal and non-neonatal tetanus based on the results from the Global Burden of Disease Study 2015. METHODS: Data from vital registration, verbal autopsy studies and mortality surveillance data covering 12,534 site-years from 1980 to 2014 were used...
February 8, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28177110/oral-health-status-knowledge-and-practice-among-pregnant-women-attending-omdurman-maternity-hospital-sudan
#15
H M El-Mahdi Ibrahim, A M Mudawi, I A Ghandour
Good oral health is important in pregnancy but little is known about the oral health and knowledge and practices of pregnant Sudanese women. This cross-sectional study was conducted to address this gap. A sample of 420 pregnant women attending the prenatal clinic at Omdurman maternity hospital were interviewed and examined for caries and periodontal disease. The mean age of the women was 27.1 (SD 5.8) years, 52.4% had > primary school education and 7.1% were employed. Only 12% had a high level of oral health knowledge and 21...
February 1, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/28173839/characterisation-of-larval-habitats-species-composition-and-factors-associated-with-the-seasonal-abundance-of-mosquito-fauna-in-gezira-sudan
#16
Mostafa M Mahgoub, Eliningaya J Kweka, Yousif E Himeidan
BACKGROUND: Larval source management (LSM), which requires an understanding of the ecology and composition of the local mosquito fauna, is an important parameter in successful vector control programmes. The present study was conducted to understand the distribution of larval habitats, species composition and factors associated with the seasonal abundance of mosquito larvae in Gezira irrigation Scheme in Gezira state, central Sudan. METHODS: Cross-sectional larval surveys were carried out in the communities of Barakat (urban) and El-Kareiba (semi-urban), in Wad Madani, Gezira...
February 8, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28169066/standardization-and-validation-of-simple-pcr-duplex-pcr-and-rapd-in-comparison-to-blood-smear-examination-for-diagnosing-bovine-tropical-theileriosis
#17
Vikrant Sudan, Daya Shanker, Amit Jaiswal, Amit Singh, Vijay Pandey
Bovine Tropical Theileriosis (BTT) is an important vector-borne protozoan disease that imposing serious constraints on the health and productivity of domestic cattle. It is matter of common fact that following recovery from primary infection, cattle become persistent carriers and act as reservoirs of infection thereby, playing a critical role in disease epidemiology. The present study describes the comparative diagnostic efficiency of simplex PCR, duplex PCR and RAPD assays for detection of Theileria annulata in cattle...
February 3, 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28167539/chemically-modified-human-serum-albumin-potently-blocks-entry-of-ebola-pseudoviruses-and-virus-like-particles
#18
Haoyang Li, Fei Yu, Shuai Xia, Yufeng Yu, Qian Wang, Ming Lv, Yan Wang, Shibo Jiang, Lu Lu
Ebola virus (EBOV), causative pathogen of the deadly Ebola virus disease (EVD), can be transmitted via contact with EVD patients, including sexual contact with EVD survivors. At present, no licensed vaccine or therapeutic is available. In this study, we compared eight anhydride-modified proteins for their inhibitory activity against entry of the pseudovirus (PsV) carrying the envelope glycoprotein (GP) of EBOV Zaire or Sudan species. We found that 3-hydroxyphthalic anhydride-modified human serum albumin (HP-HSA) was most effective in inhibiting entry of both Zaire-PsV and Sudan-PsV, with EC50 at nanomolar level, more potent than EBOV-neutralizing antibody, MIL77-2 (4G7)...
February 6, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28165661/robust-universal-biomarker-assay-to-detect-senescent-cells-in-biological-specimens
#19
Konstantinos Evangelou, Nikolaos Lougiakis, Sophia V Rizou, Athanassios Kotsinas, Dimitris Kletsas, Daniel Muñoz-Espín, Nikolaos G Kastrinakis, Nicole Pouli, Panagiotis Marakos, Paul Townsend, Manuel Serrano, Jiri Bartek, Vassilis G Gorgoulis
Cellular senescence contributes to organismal development, aging, and diverse pathologies, yet available assays to detect senescent cells remain unsatisfactory. Here, we designed and synthesized a lipophilic, biotin-linked Sudan Black B (SBB) analogue suitable for sensitive and specific, antibody-enhanced detection of lipofuscin-containing senescent cells in any biological material. This new hybrid histo-/immunochemical method is easy to perform, reliable, and universally applicable to assess senescence in biomedicine, from cancer research to gerontology...
February 2017: Aging Cell
https://www.readbyqxmd.com/read/28162058/prevalence-of-epilepsy-in-74-949-school-children-in-khartoum-state-sudan
#20
Inaam N Mohamed, Maha A Elseed, Ahlam A Hamed, Manar E Abdel-Rahman, Sarah M El-Sadig, Ilham M Omer, Abdelgadir H Osman, Ammar E Ahmed, Zein A Karrar, Mustafa A Salih
BACKGROUND: Data on childhood epilepsy in Sudan are scarce and the only published study on its prevalence was published in 1983. This study aimed to determine the current prevalence of epilepsy in school children in Khartoum State. METHODS: This is an analytical population-based, cross-sectional study conducted in Khartoum State, Sudan. The study included students in the basic (primary) schools aged 6-14 years. Simple random sampling was used to draw a cluster of four of the seven localities comprising Khartoum State...
February 6, 2017: Paediatrics and International Child Health
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