keyword
MENU ▼
Read by QxMD icon Read
search

Medication

keyword
https://www.readbyqxmd.com/read/29475122/blue-light-irradiation-triggers-the-antimicrobial-potential-of-zno-nanoparticles-on-drug-resistant-acinetobacter-baumannii
#1
Ming-Yeh Yang, Kai-Chih Chang, Liang-Yu Chen, Po-Ching Wang, Chih-Chiang Chou, Zhong-Bin Wu, Anren Hu
Photodynamic inactivation (PDI) is a non-invasive and safe therapeutic method for microbial infections. Bacterial antibiotic resistance is caused by antibiotics abuse. Drug-resistant Acinetobacter spp. is a serious problem in hospitals around the world. These pathogens from nosocomial infections have high mortality rates in frailer people, and Acinetobacter spp. is commonly found in immunocompromised patients. Visible light is safer than ultraviolet light (UV) for PDI of nosocomial pathogens with mammalian cells...
February 6, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29475120/infant-fatality-case-with-excessive-chylous-ascites
#2
Nozomi Idota, Mami Nakamura, Misa Tojo, Hiroaki Ichioka, Kaori Shintani-Ishida, Hiroshi Ikegaya
An 11-month-old boy with marked abdominal distension was found dead in the prone position at home. Since there were many bruises in the non-protruding regions of the head, face, and abdomen, a medicolegal autopsy was performed the following day. The boy was smaller than average (height: 68.5 cm; weight: 7.8 kg); his extremities were thin; and his abdomen was remarkably bulging. Chylous ascites (1600 mL) was observed in the peritoneal cavity and chylous pleural effusion (left: 5 mL; right: 10 mL) in the thoracic cavity...
February 16, 2018: Legal Medicine
https://www.readbyqxmd.com/read/29475098/xq-1h-protects-against-ischemic-stroke-by-regulating-microglia-polarization-through-ppar%C3%AE-pathway-in-mice
#3
Rui Liu, Junjian Diao, Shucheng He, Binbin Li, Yuxiang Fei, Yunman Li, Weirong Fang
Cerebral ischemic and reperfusion injury often accompany with inflammation, and lead to severe neuronal damage, which further result in neurological disorders and memory disorders. In this study, we researched XQ-1H, a novel derivative of ginkgolide B, protecting against ischemic stroke in mice through regulation of microglia polarization. Middle cerebral artery occlusion (MCAO)/reperfusion in mice is applied to mimic ischemic stroke in vivo. Immediately after MCAO, mice are intragastric administrated with different dose (31 or 62 mg/kg) of XQ-1H for one or continuative three days...
February 20, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29475093/nurse-practitioner-independence-health-care-utilization-and-health-outcomes
#4
Jeffrey Traczynski, Victoria Udalova
Many states allow nurse practitioners (NPs) to practice and prescribe drugs without physician oversight, increasing the number of autonomous primary care providers. We estimate the causal impact of NP independence on population health care utilization rates and health outcomes, exploiting variation in the timing of state law passage. We find that NP independence increases the frequency of routine checkups, improves care quality, and decreases emergency room use by patients with ambulatory care sensitive conditions...
January 17, 2018: Journal of Health Economics
https://www.readbyqxmd.com/read/29475026/results-of-interdisciplinary-management-of-693-patients-with-aneurysmal-subarachnoid-hemorrhage-clinical-outcome-and-relevant-prognostic-factors
#5
Muhammad AlMatter, Marta Aguilar Péreza, Pervinder Bhogal, Victoria Hellstern, Oliver Ganslandt, Hans Henkes
OBJECTIVES: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high rates of morbidities and fatalities. The continuous evolution of neurosurgical, endovascular and neuro-intensive cares has improved the overall mortality. In this study we sought to evaluate the clinical outcome after aSAH from a single tertiary center. PATIENTS AND METHODS: We retrospectively identified and reviewed all consecutive patients with aSAH treated at our center between 2007 and 2016...
February 13, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29475010/impact-of-a-mental-health-based-primary-care-program-on-emergency-department-visits-and-inpatient-stays
#6
Joshua Breslau, Emily Leckman-Westin, Bing Han, Riti Pritam, Diana Guarasi, Marcela Horvitz-Lennon, Deborah M Scharf, Molly T Finnerty, Hao Yu
OBJECTIVE: Integrating primary care services into specialty mental health clinics has been proposed as a method for improving health care utilization for medical conditions by adults with serious mental illness. This paper examines the impact of a mental health based primary care program on emergency department (ED) visits and hospitalizations. METHOD: The program was implemented in seven New York City outpatient mental health clinics in two waves. Medicaid claims were used to identify patients treated in intervention clinics and a control group of patients treated in otherwise similar clinics in New York City...
February 17, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29474972/risk-factors-for-fecal-urgency-among-individuals-with-and-without-diarrhea-based-on-data-from-the-national-health-and-nutrition-examination-survey
#7
Vikram Rangan, Shuji Mitsuhashi, Prashant Singh, Sarah Ballou, William Hirsch, Thomas Sommers, Judy Nee, Johanna Iturrino, Anthony Lembo
BACKGROUND & AIMS: Fecal urgency is a common symptom among patients with gastrointestinal disorders, but can also occur in healthy individuals with normal bowel habits. There have been few studies of fecal urgency in the general population. We performed a cross-sectional analysis of data from the National Health and Nurition Examination Survey (NHANES) to analyze the prevalence of and risk factors for this symptom. METHODS: We analyzed data from 4,676 persons who completed the Bowel Health Questionnaire from the NHANES, from 2009 through 2010...
February 20, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29474971/pre-diagnosis-use-of-statins-associates-with-increased-survival-times-of-patients-with-pancreatic-cancer
#8
Tsuyoshi Hamada, Natalia Khalaf, Chen Yuan, Vicente Morales-Oyarvide, Ana Babic, Jonathan A Nowak, Zhi Rong Qian, Kimmie Ng, Douglas A Rubinson, Peter Kraft, Edward L Giovannucci, Meir J Stampfer, Charles S Fuchs, Shuji Ogino, Brian M Wolpin
BACKGROUND & AIMS: Statin medications, most commonly prescribed to reduce lipid levels and prevent cardiovascular disease, may be associated with longer survival times of patients with cancer. However, the association of statins with outcomes of patients with pancreatic adenocarcinoma is not clear. METHODS: We analyzed the association of statin use before a diagnosis of pancreatic cancer with survival times of 648 participants in the Nurses' Health Study and Health Professionals Follow-up Study who were diagnosed with pancreatic adenocarcinoma from 2000 through 2013...
February 20, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29474911/identifying-medical-diagnoses-and-treatable-diseases-by-image-based-deep-learning
#9
Daniel S Kermany, Michael Goldbaum, Wenjia Cai, Carolina C S Valentim, Huiying Liang, Sally L Baxter, Alex McKeown, Ge Yang, Xiaokang Wu, Fangbing Yan, Justin Dong, Made K Prasadha, Jacqueline Pei, Magdalena Ting, Jie Zhu, Christina Li, Sierra Hewett, Jason Dong, Ian Ziyar, Alexander Shi, Runze Zhang, Lianghong Zheng, Rui Hou, William Shi, Xin Fu, Yaou Duan, Viet A N Huu, Cindy Wen, Edward D Zhang, Charlotte L Zhang, Oulan Li, Xiaobo Wang, Michael A Singer, Xiaodong Sun, Jie Xu, Ali Tafreshi, M Anthony Lewis, Huimin Xia, Kang Zhang
The implementation of clinical-decision support algorithms for medical imaging faces challenges with reliability and interpretability. Here, we establish a diagnostic tool based on a deep-learning framework for the screening of patients with common treatable blinding retinal diseases. Our framework utilizes transfer learning, which trains a neural network with a fraction of the data of conventional approaches. Applying this approach to a dataset of optical coherence tomography images, we demonstrate performance comparable to that of human experts in classifying age-related macular degeneration and diabetic macular edema...
February 22, 2018: Cell
https://www.readbyqxmd.com/read/29474887/genome-writing-current-progress-and-related-applications
#10
Yueqiang Wang, Yue Shen, Ying Gu, Shida Zhu, Ye Yin
The ultimate goal of synthetic biology is to build customized cells or organisms to meet specific industrial or medical needs. The most important part of the customized cell is a synthetic genome. Advanced genomic writing technologies are required to build such an artificial genome. Recently, the partially-completed synthetic yeast genome project represents a milestone in this field. In this mini review, we briefly introduce the techniques for de novo genome synthesis and genome editing. Furthermore, we summarize recent research progresses and highlight several applications in the synthetic genome field...
February 20, 2018: Genomics, Proteomics & Bioinformatics
https://www.readbyqxmd.com/read/29474881/ruptured-extracranial-carotid-artery-endovascular-treatment-with-covered-stent-graft
#11
Ho Cheol Choi, Sung Eun Park, Dae Seob Choi, Hwa Seon Shin, Ji-Eun Kim, Hye Young Choi, Mi Jung Park, Eun Ha Koh
BACKGROUND AND PURPOSE: Rupture of the extracranial carotid artery is a rare, but potentially disastrous event. We aimed to review the clinical presentations and radiologic findings of this entity and to evaluate the efficacy of endovascular treatment with covered stent graft. MATERIALS AND METHODS: Since January 2009, eight patients with extracranial carotid artery rupture received endovascular treatment with covered stent graft. We retrospectively reviewed their medical records and radiologic findings...
February 20, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29474877/the-grp78-bip-inhibitor-ha15-synergizes-with-mitotane-action-against-adrenocortical-carcinoma-cells-through-convergent-activation-of-er-stress-pathways
#12
Carmen Ruggiero, Mabrouka Doghman-Bouguerra, Cyril Ronco, Rachid Benhida, Stéphane Rocchi, Enzo Lalli
Many types of cancer cells present constitutively activated ER stress pathways because of their significant burden of misfolded proteins coded by mutated and rearranged genes. Further increase of ER stress by pharmacological intervention may shift the balance towards cell death and can be exploited therapeutically. Recent studies have shown that an important component in the mechanism of action of mitotane, the only approved drug for the medical treatment of adrenocortical carcinoma (ACC), is represented by activation of ER stress through inhibition of the SOAT1 enzyme and accumulation of toxic lipids...
February 20, 2018: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/29474865/trajectories-of-plasma-igf-1-igfbp-3-and-their-ratio-in-the-mayo-clinic-study-of-aging
#13
Alexandra M V Wennberg, Clinton E Hagen, Ronald C Petersen, Michelle M Mielke
Insulin-like growth factor 1 (IGF-1) has been associated with osteoporosis, cardiovascular disease, cancer, neurodegenerative diseases, and mortality in middle and older aged adults. Cross-sectionally, IGF-1 decreases with age and levels of IGF-1 are markedly different between individuals. However, little is known about intra-individual trajectories of IGF-1. We examined baseline and serial measures of plasma total IGF-1, IGF binding protein (IGFBP)-3, and their ratio, which is a proxy for bioavailable IGF-1, among 1618 adults, aged 50-95, enrolled in the Mayo Clinic Study of Aging...
February 20, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29474791/just-another-ordinary-bad-birth-a-narrative-analysis-of-first-time-mothers-traumatic-birth-experiences
#14
Helen Murphy, Joanna Strong
A difficult birth experience can have long lasting psychological effects on both mother and baby and this study details 4 in-depth accounts of first time mothers who described their birth experience as traumatizing. Narrative analysis was used to record discrepancies between the ideal and the real and produced narrative accounts that highlighted how these mothers felt invisible and dismissed in a medical culture of engineering obstetrics. Participants also detailed how their birth experience could be improved and this is set in context alongside current recommendations in maternal health care and the complexities of delivering such care in UK health settings...
February 23, 2018: Health Care for Women International
https://www.readbyqxmd.com/read/29474707/immune-relevant-models-for-ocular-inflammatory-diseases
#15
Brian C Gilger
Ocular inflammatory diseases, such as dry eye and uveitis, are common, painful, difficult to treat, and may result in vision loss or blindness. Ocular side effects from the use of antiinflammatory drugs (such as corticosteroids or nonsteroidal antiinflammatories) to treat ocular inflammation have prompted development of more specific and safer medications to treat inflammatory and immune-mediated diseases of the eye. To assess the efficacy and safety of these new therapeutics, appropriate immune-relevant animal models of ocular inflammation are needed...
February 21, 2018: ILAR Journal
https://www.readbyqxmd.com/read/29474687/enhanced-automatic-action-imitation-and-intact-imitation-inhibition-in-schizophrenia
#16
Arndis Simonsen, Riccardo Fusaroli, Joshua Charles Skewes, Andreas Roepstorff, Daniel Campbell-Meiklejohn, Ole Mors, Vibeke Bliksted
Imitation plays a key role in social learning and in facilitating social interactions and likely constitutes a basic building block of social cognition that supports higher-level social abilities. Recent findings suggest that patients with schizophrenia have imitation impairments that could contribute to the social impairments associated with the disorder. However, extant studies have specifically assessed voluntary imitation or automatic imitation of emotional stimuli without controlling for potential confounders...
February 21, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29474659/communication-failure-analysis-of-prescribers-use-of-an-internal-free-text-field-on-electronic-prescriptions
#17
Angela Ai, Adrian Wong, Mary Amato, Adam Wright
Importance: Electronic prescribing promises to improve the safety and clarity of prescriptions. However, it also can introduce miscommunication between prescribers and pharmacists. There are situations where information that is meant to be sent to pharmacists is not sent to them, which has the potential for dangerous errors. Objective: To examine how frequently prescribers or administrative personnel put information intended for pharmacists in a field not sent to pharmacists, classify the type of information included, and assess the potential harm associated with these missed messages...
February 21, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29474638/star-chimeric-post-for-rapid-detection-of-circular-rna-and-fusion-transcripts
#18
Nicholas K Akers, Eric E Schadt, Bojan Losic
Motivation: The biological relevance of chimeric RNA alignments is now well established. Chimera arising as chromosomal fusions are often drivers of cancer, and recently discovered circular RNA are only now being characterized. While software already exists for fusion discovery and quantitation, high false positive rates and high run-times hamper scalable fusion discovery on large datasets. Furthermore, software available for circular RNA detection and quantification is limited. Results: Here we present STAR Chimeric Post (STARChip), a novel software package that processes chimeric alignments from the STAR aligner and produces annotated circular RNA and high precision fusions in a rapid, efficient, and scalable manner that is appropriate for high dimensional medical omics datasets...
February 20, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29474481/a-dual-boundary-classifier-for-predicting-acute-hypotensive-episodes-in-critical-care
#19
Sakyajit Bhattacharya, Vijay Huddar, Vaibhav Rajan, Chandan K Reddy
An Acute Hypotensive Episode (AHE) is the sudden onset of a sustained period of low blood pressure and is one among the most critical conditions in Intensive Care Units (ICU). Without timely medical care, it can lead to an irreversible organ damage and death. By identifying patients at risk for AHE early, adequate medical intervention can save lives and improve patient outcomes. In this paper, we design a novel dual-boundary classification based approach for identifying patients at risk for AHE. Our algorithm uses only simple summary statistics of past Blood Pressure measurements and can be used in an online environment facilitating real-time updates and prediction...
2018: PloS One
https://www.readbyqxmd.com/read/29474391/support-service-utilization-and-out-of-pocket-payments-for-health-services-in-a-population-based-sample-of-adults-with-neurological-conditions
#20
Adebimpe O Obembe, Charlie H Goldsmith, Lisa A Simpson, Brodie M Sakakibara, Janice J Eng
BACKGROUND: Social support can help to deal with the consequences of neurological conditions and promote functional independence and quality of life. Our aim was to evaluate the impact of neurological conditions on the use of support and health-care services in a population-based sample of community-dwelling adults with neurological conditions. METHODS: Data were from the Survey of Living with Neurological Conditions in Canada, which was derived from a representative sample of household residents...
2018: PloS One
keyword
keyword
2379
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"