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https://www.readbyqxmd.com/read/29920992/solution-proceed-air-stable-copper-bismuth-iodide-cubii%C3%A2-for-photovoltaics
#1
Zhaosheng Hu, Zhen Wang, Gaurav Kapil, Tingli Ma, Satoshi Iikubo, Takashi Minemoto, Kenji Yoshino, Taro Toyoda, Qing Shen, Shuzi Hayase
Bismuth based solar cells have been under intensive interest as an efficient non-toxic absorber in photovoltaics. Within this new family of semiconductors, we herein, report a new, long-term stable material copper bismuth iodide (CuBiI₄). A solution-processed method is provided under air atmosphere. The adopted HI assisted Dimethylacetamide (DMA) co-solvent can completely dissolve CuI and BiI₃ powders with high concentration compared to other organic solvent. Moreover, high vapor pressure of Tributyl phosphate, we select for the solvent vapor annealing (SVA), enables the whole low-temperature (≤70⁰C) film preparation...
June 19, 2018: ChemSusChem
https://www.readbyqxmd.com/read/29920723/protective-effects-of-timosaponin-bii-on-oxidative-stress-damage-in-pc12-cells-based-on-metabolomic
#2
REVIEW
Qinmei Xie, Hongxia Zhao, Na Li, Li Su, Xu Xu, Zhanying Hong
Peroxide and oxygen free radical are parts of the causes of oxidative stress in brain tissue, which could lead to the change of brain structure and function. Besides, oxidative damage is one of the most important causes of the aging of the vast majority of tissues. The aim of this study is to investigate the protective effect of Timosaponin BII on oxidative stress damage of PC12 induced by H2 O2 using metabolomics based on the UHPLC-Q-TOF-MS technique. Partial least-squares discriminant analysis (PLS-DA) method was used to identify 35 metabolites as decisive marker compounds that preliminary interpret the mechanism of antioxidative effect of Timosaponin BII...
June 19, 2018: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29902048/measuring-variations-in-bicultural-identity-across-u-s-ethnic-and-generational-groups-development-and-validation-of-the-bicultural-identity-integration-scale-version-2-biis-2
#3
Que-Lam Huynh, Verònica Benet-Martínez, Angela-MinhTu D Nguyen
Bicultural Identity Integration (BII) is an individual difference construct that captures variations in the experience of biculturalism. Using multiple samples in a series of steps, we refined BII measurement and then tested the construct in a diverse sample of bicultural individuals. Specifically, we wrote new BII items based on qualitative data ( n = 108), examined the quality of the new measure using subject-matter experts ( n = 23) and bicultural individuals ( n = 5), and then collected validation data from bicultural college students ( n = 1049)...
June 14, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29883223/respiratory-insufficiency-from-myasthenia-gravis-and-polymyositis-due-to-malignant-thymoma-triggering-takotsubo-syndrome
#4
Josef Finsterer, Claudia Stöllberger, Chen-Yu Ho
BACKGROUND: Takotsubo syndrome (TTS) is a non-ischemic cardiomyopathy with sudden but transient systolic dysfunction. TTS mimics myocardial infarction clinically, chemically, and electrocardiographically but echocardiography typically shows apical ballooning and coronary angiography is normal. TTS has not been reported in a patient with myasthenia gravis (MG) and polymyositis due to a malignant thymoma. CASE REPORT: Two weeks prior to admission, a 76yo female developed dysarthria, chronic coughing, and disabling myalgias of the entire musculature...
June 8, 2018: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29805716/isolation-and-identification-of-an-anthracimycin-analogue-from-nocardiopsis-kunsanensis-a-halophile-from-a-saltern-by-genomic-mining-strategy
#5
Fernanda L Sirota, Falicia Goh, Kia-Ngee Low, Lay-Kien Yang, Sharon C Crasta, Birgit Eisenhaber, Frank Eisenhaber, Yoganathan Kanagasundaram, Siew Bee Ng
Modern medicine is unthinkable without antibiotics; yet, growing issues with microbial drug resistance require intensified search for new active compounds. Natural products generated by Actinobacteria have been a rich source of candidate antibiotics, for example anthracimycin that, so far, is only known to be produced by Streptomyces species. Based on sequence similarity with the respective biosynthetic cluster, we sifted through available microbial genome data with the goal to find alternative anthracimycin-producing organisms...
2018: Journal of Genomics
https://www.readbyqxmd.com/read/29780535/-de-novo-design-of-d-%C3%AF-a-molecules-as-universal-hosts-for-monochrome-and-white-phosphorescent-organic-light-emitting-diodes
#6
Wen-Cheng Chen, Yi Yuan, Ze-Lin Zhu, Zuo-Quan Jiang, Shi-Jian Su, Liang-Sheng Liao, Chun-Sing Lee
Two novel D-σ-A host materials 11,11-bis(9-phenyl-9 H -carbazol-3-yl)-11 H -benzo[4,5]imidazo[1,2- a ]indole (BII-BCz) and 4,4'-(11 H -benzo[4,5]imidazo[1,2- a ]indole-11,11-diyl)bis( N , N -diphenylaniline) (BII-TPA) are synthesized by using the sp3 carbon attached to a newly designed 11 H -benzo[4,5]imidazo[1,2- a ]indole building block to link two electron-donating groups. The resulting materials feature high triplet energy levels, good thermal properties and suitable photophysical properties as universal hosts for full-color phosphorescent organic light-emitting diodes (OLEDs)...
May 7, 2018: Chemical Science
https://www.readbyqxmd.com/read/29757957/arthroprotective-effects-of-cf-02-sharing-structural-similarity-with-quercetin
#7
Feng-Cheng Liu, Jeng-Wei Lu, Chiao-Yun Chien, Hsu-Shan Huang, Chia-Chung Lee, Shiu-Bii Lien, Leou-Chyr Lin, Liv Weichien Chen, Yi-Jung Ho, Min-Chung Shen, Ling-Jun Ho, Jenn-Haung Lai
In this study, we synthesized hundreds of analogues based on the structure of small-molecule inhibitors (SMIs) that were previously identified in our laboratory with the aim of identifying potent yet safe compounds for arthritis therapeutics. One of the analogues was shown to share structural similarity with quercetin, a potent anti-inflammatory flavonoid present in many different fruits and vegetables. We investigated the immunomodulatory effects of this compound, namely 6-(2,4-difluorophenyl)-3-(3-(trifluoromethyl)phenyl)-2 H -benzo[ e ][1,3]oxazine-2,4(3 H )-dione (Cf-02), in a side-by-side comparison with quercetin...
May 14, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29686187/contribution-to-the-knowledge-of-chinese-phasmatodea-iv-taxonomy-on-medaurini-phasmatodea-phasmatidae-clitumninae-of-china
#8
George Wai-Chun Ho
This paper deals with the taxonomy of Chinese Medaurini with descriptions of two new genera, 14 new species and two new subspecies, proposal of two new combinations and report of two new records for China. A total of seven genera and 42 species are recognised in the tribe. Ten new species and two new subspecies from four recognised genera including Cnipsomorpha Hennemann, Conle, Zhang Liu, 2008, Interphasma Chen He, 2008, Medauroidea Zompro, 2000 and Parapachymorpha Brunner von Wattenwyl, 1893 are described...
December 20, 2017: Zootaxa
https://www.readbyqxmd.com/read/29655325/an-atomic-mean-field-spin-orbit-approach-within-exact-two-component-theory-for-a-non-perturbative-treatment-of-spin-orbit-coupling
#9
Junzi Liu, Lan Cheng
An atomic mean-field (AMF) spin-orbit (SO) approach within exact two-component theory (X2C) is reported, thereby exploiting the exact decoupling scheme of X2C, the one-electron approximation for the scalar-relativistic contributions, the mean-field approximation for the treatment of the two-electron SO contribution, and the local nature of the SO interactions. The Hamiltonian of the proposed SOX2CAMF scheme comprises the one-electron X2C Hamiltonian, the instantaneous two-electron Coulomb interaction, and an AMF SO term derived from spherically averaged Dirac-Coulomb Hartree-Fock calculations of atoms; no molecular relativistic two-electron integrals are required...
April 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29649637/angiogenesis-impairment-by-the-nadph-oxidase-triggered-oxidative-stress-at-the-bone-implant-interface-critical-mechanisms-and-therapeutic-targets-for-implant-failure-under-hyperglycemic-conditions-in-diabetes
#10
Xiao-Fan Hu, Lin Wang, Geng Xiang, Wei Lei, Ya-Fei Feng
Mechanism underlying the diabetes-induced poor osteointegration of implants remains elusive, making it a challenge to develop corresponding solutions. Here, we studied the role of angiogenesis in the diabetes-induced poor bone repair at the bone-implant interface (BII) and the related mechanisms. In vivo, titanium screws were implanted in the femurs of mice, and, in vitro, vascular endothelial cell (VEC) was cultured on titanium surface. Results showed that, compared with normal milieu (NM), diabetic milieu (DM) led to angiogenesis inhibition around implants which resulted in reduced osteoprogenitors and poor bone formation on BII in vivo...
June 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29643985/replication-incompetent-gammaretroviral-and-lentiviral-vector-based-insertional-mutagenesis-screens-identify-prostate-cancer-progression-genes
#11
Victor M Bii, Casey P Collins, Jonah D Hocum, Grant D Trobridge
Replication-incompetent gammaretroviral (γRV) and lentiviral (LV) vectors have both been used in insertional mutagenesis screens to identify cancer drivers. In this approach the vectors stably integrate in the host cell genome and induce cancers by dysregulating nearby genes. The cells that contain a retroviral vector provirus in or near a proto-oncogene or tumor suppressor are preferentially enriched in a tumor. γRV and LV vectors have different integration profiles and genotoxic potential, making them potentially complementary tools for insertional mutagenesis screens...
March 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29625790/transfusion-associated-hazards-a-revisit-of-their-presentation
#12
O Garraud, C Sut, A Haddad, S Tariket, C Aloui, S Laradi, H Hamzeh-Cognasse, T Bourlet, F Zeni, C Aubron, Y Ozier, S Laperche, T Peyrard, P Buffet, D Guyotat, E Tavernier, F Cognasse, B Pozzetto, G Andreu
As a therapy or a support to other therapies, despite being largely beneficial to patients in general, transfusion it is not devoid of some risks. In a moderate number of cases, patients may manifest adverse reactions, otherwise referred to as transfusion-associated hazards (TAHs). The latest French 2016 haemovigilance report indicates that 93% of TAHs are minor (grade 1), 5.5% are moderate (grade 2) and 1.6% are severe (grade 3), with only five deaths (grade 4) being attributed to transfusion with relative certainty (imputability of level [or grade] 1 to 3)...
May 2018: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29608059/-c-6-h-13-n-2-bii-5-a-one-dimensional-lead-free-perovskite-derivative-photoconductive-light-absorber
#13
Weichuan Zhang, Kewen Tao, Chengmin Ji, Zhihua Sun, Shiguo Han, Jing Zhang, Zhenyue Wu, Junhua Luo
Lead-free organic-inorganic hybrid perovskites have recently attracted intense interest as environmentally friendly, low-cost, chemically stable light absorbers. Here, we reported a new one-dimensional (1D) zigzag chainlike light-absorbing hybrid material of (C6 H13 N)2 BiI5 , in which the corner-sharing octahedral bismuth halide chains are surrounded by organic cations of tetramethylpiperidinium. This unique zigzag 1D hybrid perovskite-derivative material shows a narrow direct band gap of 2.02 eV and long-lived photoluminescence, which is encouraging for optoelectronic applications...
April 16, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/29600908/pedicle-screws-with-a-thin-hydroxyapatite-coating-for-improving-fixation-at-the-bone-implant-interface-in-the-osteoporotic-spine-experimental-study-in-a-porcine-model
#14
Makoto Ohe, Hiroshi Moridaira, Satoshi Inami, Daisaku Takeuchi, Yutaka Nohara, Hiroshi Taneichi
OBJECTIVE Instrumentation failure caused by the loosening of pedicle screws (PSs) in patients with osteoporosis is a serious problem after spinal surgery. The addition of a thin hydroxyapatite (HA) surface coating applied by using a sputtering process was reported recently to be a promising method for providing bone conduction around an implant without a significant risk of coating-layer breakage. In this study, the authors evaluated the biomechanical and histological features of the bone-implant interface (BII) of PSs with a thin HA coating in an in vivo porcine osteoporotic spine model...
March 30, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29577220/-comparison-of-the-safety-and-the-costs-between-laparoscopic-assisted-or-totally-laparoscopic-uncut-roux-en-y-and-billrothii-braun-reconstruction-a-single-center-prospective-cohort-study
#15
Yinkui Wang, Ziyu Li, Fei Shan, Lianhai Zhang, Shuangxi Li, Yongning Jia, Yufan Chen, Kan Xue, Rulin Miao, Zhemin Li, Xiangyu Gao, Chao Yan, Shen Li, Zhouqiao Wu, Jiafu Ji
OBJECTIVE: To compare the short-term safety and costs between laparoscopic assisted or totally laparoscopic uncut Roux-en-Y and Billroth II((BII() + Braun reconstruction after radical gastrectomy of distal gastric cancer. METHODS: Clinical data from our prospective database of radical gastrectomy were systematically analyzed. The patients who underwent laparoscopic gastrectomy with uncut Roux-en-Y or BII(+ Braun reconstruction between March 1st, 2015 and June 30th, 2017 were screened out for further analysis...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29534535/chondroprotective-effects-and-mechanisms-of-dextromethorphan-repurposing-antitussive-medication-for-osteoarthritis-treatment
#16
Liv Weichien Chen, Feng-Cheng Liu, Li-Feng Hung, Chuan-Yueh Huang, Shiu-Bii Lien, Leou-Chyr Lin, Jenn-Haung Lai, Ling-Jun Ho
Osteoarthritis (OA) is the most common joint disorder and primarily affects older people. The ideal anti-OA drug should have a modest anti-inflammatory effect and only limited or no toxicity for long-term use. Because the antitussive medication dextromethorphan (DXM) is protective in atherosclerosis and neurological diseases, two common disorders in aged people, we examined whether DXM can be protective in pro-inflammatory cytokine-stimulated chondrocytes and in a collagen-induced arthritis (CIA) animal model in this study...
March 12, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29513847/building-infestation-index-for-aedes-aegypti-and-occurrence-of-dengue-fever-in-the-municipality-of-foz-do-igua%C3%A3-u-paran%C3%A3-brazil-from-2001-to-2016
#17
Açucena Veleh Rivas, Renata Defante, Robson Michael Delai, Jean Avemir Rios, André da Silva Britto, André de Souza Leandro, Daniela Dib Gonçalves
INTRODUCTION: the Building Infestation Index (BII) uses the Rapid Assay of the Larval Index for Aedes aegypti (LIRAa) to express the relationship between positive and surveyed properties. We evaluated LIRAa and the relationship between the BII and climate variables for dengue cases in Foz do Iguaçu municipality, Paraná. METHODS: Spearman's correlations for mean precipitation, mean temperature, BII, and dengue cases (time lag). RESULTS: positive correlations between BII and cases, and mean temperature and cases at two months...
January 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29513759/subtype-assignment-of-cll-based-on-b-cell-subset-associated-gene-signatures-from-normal-bone-marrow-a-proof-of-concept-study
#18
Caroline Holm Nørgaard, Lasse Hjort Jakobsen, Andrew J Gentles, Karen Dybkær, Tarec Christoffer El-Galaly, Julie Støve Bødker, Alexander Schmitz, Preben Johansen, Tobias Herold, Karsten Spiekermann, Jennifer R Brown, Josephine L Klitgaard, Hans Erik Johnsen, Martin Bøgsted
Diagnostic and prognostic evaluation of chronic lymphocytic leukemia (CLL) involves blood cell counts, immunophenotyping, IgVH mutation status, and cytogenetic analyses. We generated B-cell associated gene-signatures (BAGS) based on six naturally occurring B-cell subsets within normal bone marrow. Our hypothesis is that by segregating CLL according to BAGS, we can identify subtypes with prognostic implications in support of pathogenetic value of BAGS. Microarray-based gene-expression samples from eight independent CLL cohorts (1,024 untreated patients) were BAGS-stratified into pre-BI, pre-BII, immature, naïve, memory, or plasma cell subtypes; the majority falling within the memory (24...
2018: PloS One
https://www.readbyqxmd.com/read/29505032/single-cell-developmental-classification-of-b-cell-precursor-acute-lymphoblastic-leukemia-at-diagnosis-reveals-predictors-of-relapse
#19
Zinaida Good, Jolanda Sarno, Astraea Jager, Nikolay Samusik, Nima Aghaeepour, Erin F Simonds, Leah White, Norman J Lacayo, Wendy J Fantl, Grazia Fazio, Giuseppe Gaipa, Andrea Biondi, Robert Tibshirani, Sean C Bendall, Garry P Nolan, Kara L Davis
Insight into the cancer cell populations that are responsible for relapsed disease is needed to improve outcomes. Here we report a single-cell-based study of B cell precursor acute lymphoblastic leukemia at diagnosis that reveals hidden developmentally dependent cell signaling states that are uniquely associated with relapse. By using mass cytometry we simultaneously quantified 35 proteins involved in B cell development in 60 primary diagnostic samples. Each leukemia cell was then matched to its nearest healthy B cell population by a developmental classifier that operated at the single-cell level...
May 2018: Nature Medicine
https://www.readbyqxmd.com/read/29473301/a-novel-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-method-for-the-simultaneous-determination-of-xanthones-and-steroidal-saponins-in-crude-and-salt-processed-anemarrhenae-rhizoma-aqueous-extracts
#20
De Ji, Xiaonan Su, Ziyan Huang, Qiaohan Wang, Tulin Lu
We established a rapid and sensitive ultra high-performance liquid chromatography tandem mass spectrometry method for the simultaneous quantification of xanthones and steroidal saponins in rat plasma. Chromatographic separation was achieved on a C18 column with a mobile phase comprising acetonitrile and 0.1% formic acid. The detection was performed by negative electrospray ionization in multiple reaction monitoring mode. The validated method showed good linearity within the tested range (r > 0.9945). The intra- and interday precision at high, medium, and low concentrations was less than 7...
February 23, 2018: Journal of Separation Science
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