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https://www.readbyqxmd.com/read/29667227/effects-of-knockout-of-the-receptor-for-advanced-glycation-end-products-on-bone-mineral-density-and-synovitis-in-mice-with-intra-articular-fractures
#1
Dongrim Seol, Yuki Tochigi, Ashley M Bogner, Ino Song, Douglas C Fredericks, Gail L Kurriger, Sonja M Smith, Jessica E Goetz, Joseph A Buckwalter, James A Martin
Our group employed the mouse closed intra-articular fracture (IAF) model to test the hypothesis that the innate immune system plays a role in initiating synovitis and post-traumatic osteoarthritis (PTOA) in fractured joints. A transgenic strategy featuring knockout of the receptor for advanced glycation end-products (RAGE -/- ) was pursued. The 42 and 84 mJ impacts used to create fractures were in the range previously reported to cause PTOA at 60 days post-fracture. MicroCT (µCT) was used to assess fracture patterns and epiphyseal and metaphyseal bone loss at 30 and 60 days post-fracture...
April 17, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29666736/intra-articular-entrapment-of-the-medial-epicondyle-following-a-traumatic-fracture-dislocation-of-the-elbow-in-an-adult
#2
Hicham G Abdel Nour, George S El Rassi, Jack C Daoud, Youssef G Hassan, Rami A Ayoubi, Nabih I Joukhadar
Medial epicondyle entrapment after an acute fracture dislocation of the elbow is a common finding in the pediatric population, but a rare finding in adults. We present a case of an adult patient diagnosed with a traumatic fracture dislocation of the elbow joint with intra-articular entrapment of the medial epicondyle. After initial evaluation, closed reduction was done. Stability testing after reduction showed an unstable joint; thus, open reduction and internal fixation was decided.
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29665704/low-dose-ct-of-postoperative-pelvic-fractures-a-comparison-with-radiography
#3
Thomas Eriksson, Per Berg, Claes Olerud, Adel Shalabi, Mari Hänni
Background Computed tomography (CT) is superior to conventional radiography (CR) for assessing internal fixation of pelvic fractures, but with a higher radiation exposure. Low-dose CT (LDCT) could possibly have a sufficient diagnostic accuracy but with a lower radiation dose. Purpose To compare postoperative diagnostic accuracy of LDCT and CR after open reduction and internal fixation of pelvic fracture. Material and Methods Twenty-one patients were examined with LDCT and CR 0-9 days after surgery. The examinations were reviewed by two musculoskeletal radiologists...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29665618/pseudo-and-conditional-score-approach-to-joint-analysis-of-current-count-and-current-status-data
#4
Chi-Chung Wen, Yi-Hau Chen
We develop a joint analysis approach for recurrent and nonrecurrent event processes subject to case I interval censorship, which are also known in literature as current count and current status data, respectively. We use a shared frailty to link the recurrent and nonrecurrent event processes, while leaving the distribution of the frailty fully unspecified. Conditional on the frailty, the recurrent event is assumed to follow a nonhomogeneous Poisson process, and the mean function of the recurrent event and the survival function of the nonrecurrent event are assumed to follow some general form of semiparametric transformation models...
April 17, 2018: Biometrics
https://www.readbyqxmd.com/read/29665605/-shoulder-arthroplasty
#5
Anna Krukenberg, Jan-Philipp Imiolczyk, Philipp Moroder, Markus Scheibel
Shoulder arthroplasty has been performed increasingly during the last years. The concept of modern anatomic shoulder arthroplasty is based on C. S. Neer's first shoulder prosthesis in the 1950s which was originally designed for the treatment of fractures of the proximal humerus. Since then, this monoblock prosthesis has undergone many changes and improvements. By now, an anatomic reconstruction of the joint is possible. Hence, the indications for anatomic shoulder arthroplasty have been added amongst others by osteoarthritis, necrosis, rheumatoid arthritis or posttraumatic arthritis...
April 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29664804/temporary-bridge-plate-stabilization-of-unstable-elbow-fractures-and-dislocations
#6
David Edelman, Asif M Ilyas
Unstable fracture-dislocations of the elbow, and in particular the "terrible triad" injury consisting of an elbow dislocation with a fracture of the radial head and coronoid, are complex injuries that can be plagued and complicated by persistent instability. Acute and chronic instability is a difficult problem and is best managed early by avoidance and restoration of stability. A number of treatment options have been proposed to manage acute postfixation instability of the elbow joint. Traditional stabilization options include immobilization with splinting or casting, cross-articular pinning, and external fixation (hinged or static), followed by early physical therapy...
April 11, 2018: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/29664526/-perioperative-care-of-older-patients-with-hip-fractures
#7
Francisco Bengoa, Marcela Carrasco, Pedro Pablo Amenábar, Daniel Schweitzer, Eduardo Botello, Ianiv Klaber
The number of osteoporotic fractures is increasing along with population aging. Most patients with these type of fractures are older than 65 years, with multiple chronic conditions and different degrees of disability. Hip fracture is the most relevant osteoporotic fracture due to its frequency, costs, severity and complications. Multidisciplinary management is of the utmost importance to obtain good therapeutic results. We herein review the management of this fracture. Orthogeriatric joint management should be incorporated in fragility fracture treatment...
November 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29663487/relationship-between-arthroscopic-findings-of-synovitis-and-levels-of-tumor-necrosis-factor-alpha-and-matrix-metalloproteinases-in-synovial-lavage-fluid-from-patients-with-unilateral-high-mandibular-condyle-fractures
#8
Shinnosuke Nogami, Tetsu Takahashi, Kensuke Yamauchi, Yuri Takeda, Ko Ito, Masatoshi Chiba, Alexander Gaggl
BACKGROUND: Arthrocentesis has an effect of washing out inflammatory products that accumulate in the joint compartment of a dysfunctional TMJ. The procedure removes inflammatory cytokines, which are pain-causing substances, for early reduction of TMJ pain and quick recovery of jaw function, thus increasing the possibility of a successful rehabilitation. OBJECTIVE: The aim of the present study was to investigate the relationship between arthroscopy synovitis grade in patients with unilateral high condylar fractures and concentrations of the pro-inflammatory cytokines tumor necrosis factor (TNF)-alpha as well as of matrix metalloproteinases (MMPs) in washed-out synovial fluid (SF) samples obtained from those patients...
April 16, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29662775/relationship-between-heterotopic-ossification-and-traumatic-brain-injury-why-severe-traumatic-brain-injury-increases-the-risk-of-heterotopic-ossification
#9
REVIEW
Huan Huang, Wen-Xiang Cheng, Yi-Ping Hu, Jian-Hai Chen, Zheng-Tan Zheng, Peng Zhang
Heterotopic ossification (HO) is a pathological phenomenon in which ectopic lamellar bone forms in soft tissues. HO involves many predisposing factors, including congenital and postnatal factors. Postnatal HO is usually induced by fracture, burn, neurological damage (brain injury and spinal cord injury) and joint replacement. Recent studies have found that patients who suffered from bone fracture combined with severe traumatic brain injury (S-TBI) are at a significantly increased risk for HO occurrence. Thus, considerable research focused on the influence of S-TBI on fracture healing and bone formation, as well as on the changes in various osteogenic factors with S-TBI occurrence...
January 2018: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29662767/reconstruction-of-the-lateral-tibia-plateau-fracture-with-a-third-triangular-support-screw-a-biomechanical-study
#10
Eduardo Moran, Ivan Zderic, Kajetan Klos, Paul Simons, Miguel Triana, R Geoff Richards, Boyko Gueorguiev, Mark Lenz
Background: Split fractures of the lateral tibia plateau in young patients with good bone quality are commonly treated using two minimally invasive percutaneous lag screws, followed by unloading of the knee joint. Improved stability could be achieved with the use of a third screw inserted either in the jail-technique fashion or with a triangular support screw configuration. The aim of this study was to investigate under cyclic loading the compliance and endurance of the triangular support fixation in comparison with the standard two lag-screw fixation and the jail technique...
October 2017: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29661673/the-use-of-pediatric-flexible-intramedullary-nails-for-minimally-invasive-fibular-fracture-fixation
#11
James C Connors, Mark A Hardy, Duane J Ehredt, Michael A Coyer
Fibular fractures in the setting of an unstable ankle joint require surgical fixation; however, several factors contradict open surgical correction. Severe soft tissue compromise can delay adequate fracture reduction and preclude the standard incisional approach. The soft tissue envelope in the setting of obesity, diabetes, and/or peripheral vascular disease further complicates definitive treatment. Poorly timed open fixation can lead to delayed healing of the incision site, with wound breakdown and the potential for hardware failure...
April 13, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29661672/development-and-validation-of-the-foot-union-scoring-evaluation-tool-for-arthrodesis-of-foot-structures
#12
Timothy A Karthas, Jeremy J Cook, Michael R Matthews, Michael L Sganga, Daniel D Hansen, Byron Collier, Philip Basile, Emily A Cook
Reliable evaluation of osseous consolidation after pedal arthrodesis can be difficult, and the presence or absence of radiographic healing often dictates care. Plain radiographs remain the mainstay imaging tool owing to their cost, efficiency, and low radiation exposure. Applying radiographic parameters that can reliably determine osseous healing is essential. However, currently, no reliable or validated measures are available to determine osseous union of any joint in the foot or ankle. The purpose of the present study was to develop a radiographic healing scoring system that would enhance the diagnostic healing assessment after joint arthrodesis of the foot or ankle...
April 13, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29659947/pediatric-thoracic-trauma-in-iraq-and-afghanistan
#13
Ryan J Keneally, Cynthia H Shields, Albert Hsu, Howard I Prior, Kevin M Creamer
Introduction: The objective of this study is to review available data on pediatric thoracic trauma seen at U.S. military treatment facilities in Iraq and Afghanistan and describe the scope of injuries, patterns seen, and associated mortality. The results were compared with adults injured in Iraq and Afghanistan and other reports of pediatric thoracic trauma in the literature. Materials and Methods: The investigators received approval from the Uniformed Services University of the Health Sciences' institutional review board before the study...
April 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29658534/the-influence-of-osteoporotic-bone-structures-of-the-pelvic-hip-complex-on-stress-distribution-under-impact-load
#14
Katarzyna Arkusz, Tomasz Klekiel, Niezgoda Niezgoda, Romuald Będziński
PURPOSE: The aim of this study was to determine the effect of bone mineral density (BMD) on the stress distribution in pelvic-hip complex (PHC) model which included bone structures and soft tissues. Bone mass changes in osteoporosis and osteopenia were considered in this analysis. In addition, the relations between force direction and stress distribution causing PHC fractures were determined. METHODS: This paper presents the development and validation of a detailed 3D finite element model with high anatomical fidelity of the PHC and BMD changes in trabecular and cortical bones, modelled based on CT scans...
2018: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29657849/talar-process-fractures-an-overview-and-update-of-the-literature
#15
Haroon Majeed, Donald J McBride
Fractures of the lateral and the posterior processes of the talus are uncommon and frequently missed because of a low level of suspicion and difficulty in interpretation on plain radiographs. Missed fractures can lead to persistent pain and reduced function.Lateral process fractures are usually a consequence of forced dorsiflexion and inversion of fixed pronated foot. These are also commonly known as snowboarder's fractures.The posterior process of the talus is composed of medial and lateral tubercles, separated by the groove for the flexor hallucis longus tendon...
March 2018: EFORT Open Reviews
https://www.readbyqxmd.com/read/29657444/radial-axial-interosseous-load-rail-test-for-essex-lopresti-type-injuries
#16
REVIEW
Zachary C Lum, Eric G Huish, Marc A Trzeciak
Background: When approaching radial head and neck fractures, the decision for ORIF, resection, or arthroplasty is often performed intraoperatively. Factors that contribute include ligamentous and bony stability, cartilage injury, mechanical alignment as well as patient factors. Recent data has suggested conventional methods may not be sufficiently sensitive in detecting Essex Lopresti injuries. Here we describe an intraoperative technique that could objectively assess proximal radio-ulnar stability with subsequent disruption of the ligamentous structures...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29655591/open-reduction-and-internal-fixation-in-a-one-stage-anterior-cruciate-ligament-reconstruction-surgery-for-the-treatment-of-tibial-plateau-fractures-a-case-report-and-literature-review
#17
Yiqun Wang, Lianyou Wang, Tongtong Zhu, Zhongguo Liu, Guangyao Liu
Treatment of tibial plateau fractures associated with anterior cruciate ligament (ACL) injuries can be challenging. Maintaining the joint surface and axis are two main principles for the management of patients with tibial plateau fractures. Herein, we describe a patient with tibial plateau fracture of Schatzker type VI associated with complete ACL rupture. Although in a two-stage reconstruction surgery for treatment of its rupture seem to be accepted by most orthopaedic surgeons in cases of ACL injuries, we treated our patient with ORIF in a one-stage ACL reconstruction surgery...
March 15, 2018: Injury
https://www.readbyqxmd.com/read/29653443/the-role-of-clinical-examination-in-predicting-relevant-mri-findings-in-acute-knee-injuries-a-retrospective-study
#18
Daoud Makki, Saleem Mastan, Daniel Ness, Raghuram Thonse
The objective of this study was to delineate the usefulness of clinical examination and magnetic resonance imaging (MRI) in acute knee injuries. We aim to establish whether the time period post acute knee injury is related to the diagnostic accuracy of clinical examination and to investigate the strength of specific clinical examination findings in predicting a clinically relevant MRI abnormality. Seventy patients were referred to fracture clinic with an acute knee injury who subsequently went on to be investigated with MRI over 12 months...
April 13, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29653241/navigation-for-lower-limb-alignment-during-internal-fixation-of-complex-tibial-plateau-fractures
#19
B Vibert, R Pailhé, V Morin, B Rubens-Duval, D Saragaglia
In complex fractures of the proximal tibial metaphysis and epiphysis, possible adverse outcomes after internal fixation include not only joint surface incongruity, but also lower limb malalignment requiring revision surgery. Navigation has been proven effective for the intra-operative control of lower limb alignment during osteotomy and knee arthroplasty. In complex traumatic fractures, temporary fixation by a locking screw plate allows sensor positioning followed by navigation manoeuvres to adjust lower limb alignment...
April 10, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29644290/posterior-dislocation-of-a-native-hip-joint-associated-with-ipsilateral-per-trochanteric-fracture-a-rare-case-report
#20
Mazin Fageir, Manoj Kumar Puthiyavaniya Veettil
We describe a case of traumatic posterior dislocation of a native hip joint associated with ipsilateral comminuted inter-trochanteric femoral fracture. In our case, closed reduction was attempted but proved unsuccessful. Taking into account the planned subsequent intra-medullary femoral nail, open reduction through a lateral incision was undertaken. Post-operatively, the planned mobility was for a non-weight bearing period of 6 weeks followed by a partial-weight bearing period of 6 weeks before progressing to full-weight bearing...
February 2018: Trauma Case Reports
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