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https://www.readbyqxmd.com/read/29337720/update-on-the-role-of-actovegin-in-musculoskeletal-medicine-a-review-of-the-past-10-years
#1
James Brock, David Golding, Paul M Smith, Len Nokes, Alvin Kwan, Paul Y F Lee
BACKGROUND: Actovegin is a biological drug with a controversial history of use in the treatment of sports injuries during the past 60 years. Particular concerns have been raised about its ergogenic potential to enhance performance, but some of these have been based on little more than anecdote. OBJECTIVES: In this article, we review the most recent scientific evidence to determine the clinical efficacy, safety profile, and legal status of Actovegin. METHODS: We considered all studies directly commenting on experience with Actovegin use as the primary intervention within the past 10 years...
January 15, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29336958/prehospital-emergencies-in-illegal-gold-mining-sites-in-french-guiana
#2
Gérald Egmann, Pierre Tattevin, Renaud Palancade, Matthieu Nacher
INTRODUCTION: Illegal gold mining is flourishing in French Guiana, existing outside the law due to both the high cost of gold mining permits and the challenges of law enforcement within the Amazon forest. We report the characteristics of, and the medical responses to, medical emergencies in illegal gold mining sites. METHODS: We performed a retrospective study of all medical emergencies reported from illegal gold mining sites to the centralized call office of SAMU 973 from 1998 through 2000 and from 2008 through 2010...
January 11, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29324320/first-survey-of-forensically-important-insects-from-human-corpses-in-shiraz-iran
#3
Mohammad D Moemenbellah-Fard, Davood Keshavarzi, Mehran Fereidooni, Aboozar Soltani
The presence of insects on human cadavers has potential judicial value in medicolegal cases. This research emphasized the important role of insects in postmortem decomposition. It was conducted to investigate the composition and abundance of insects from human corpses during autopsies in legal medicine. It was implemented in the city of Shiraz, south Iran. Insects associated with human corpses were carefully collected and put into labelled vials. They were then identified using valid taxonomic keys. Fifteen outdoor (67%) and indoor discovered cadavers were examined...
January 3, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29321805/simultaneous-measurement-of-formic-acid-methanol-and-ethanol-in-vitreous-and-blood-samples-of-postmortem-by-headspace-gc-fid
#4
Hamideh Ghorbani, Alireza Nezami, Behjat Sheikholeslami, Arya Hedjazi, Mahnaz Ahmadimanesh
Background: Formic acid (formate) is the main reason for toxicity and death through methanol poisoning. The simultaneous determination of methanol, ethanol, and formate in the body can help to discover the cause of death and is useful in the diagnosis of acute methanol poisoning. The measurement of formate is not yet available in Iran. With regard to the increasing rate of methanol poisoning and its related mortality in Iran, as well as the main role of formate in methanol poisoning, this study was designed to set up an analytical method for the concurrent determination of ethanol, methanol, and formate...
2018: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/29317918/awareness-of-the-implementation-of-the-falsified-medicines-directive-among-pharmaceutical-companies-professionals-in-the-european-economic-area
#5
Urszula WŁodarczak, Damian Swieczkowski, Urszula Religioni, Milosz Jaguszewski, Jerzy Krysinski, Piotr Merks
Background: The Falsified Medicines Directive (FMD) is a response of the European Union to the increasing number of falsified medicines present in the legal supply chain within the Member States of the community. Effective implementation of the new regulations will depend on the effective cooperation of all parties involved in the distribution of medicinal products including the managers of pharmaceutical companies. Objective: The objective of the study was to examine awareness of the Implementation of the FMD among pharmaceutical company professionals in the European Economic Area...
October 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/29307505/practical-considerations-in-medical-cannabis-administration-and-dosing
#6
REVIEW
Caroline A MacCallum, Ethan B Russo
Cannabis has been employed medicinally throughout history, but its recent legal prohibition, biochemical complexity and variability, quality control issues, previous dearth of appropriately powered randomised controlled trials, and lack of pertinent education have conspired to leave clinicians in the dark as to how to advise patients pursuing such treatment. With the advent of pharmaceutical cannabis-based medicines (Sativex/nabiximols and Epidiolex), and liberalisation of access in certain nations, this ignorance of cannabis pharmacology and therapeutics has become untenable...
January 4, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29306883/clinical-decisions-presented-to-patients-in-hospital-encounters-a-cross-sectional-study-using-a-novel-taxonomy
#7
Eirik Hugaas Ofstad, Jan C Frich, Edvin Schei, Richard M Frankel, Jūratė Šaltytė Benth, Pål Gulbrandsen
OBJECTIVE: To identify and classify all clinical decisions that emerged in a sample of patient-physician encounters and compare different categories of decisions across clinical settings and personal characteristics. DESIGN: Cross-sectional descriptive evaluation of hospital encounters videotaped in 2007-2008 using a novel taxonomy to identify and classify clinically relevant decisions (both actions and judgements). PARTICIPANTS AND SETTING: 372 patients and 58 physicians from 17 clinical specialties in ward round (WR), emergency room (ER) and outpatient (OP) encounters in a Norwegian university hospital...
January 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/29306816/-you-got-to-love-rosin-solventless-dabs-pure-clean-natural-medicine-exploring-twitter-data-on-emerging-trends-in-rosin-tech-marijuana-concentrates
#8
Francois R Lamy, Raminta Daniulaityte, Mussah Zatreh, Ramzi W Nahhas, Amit Sheth, Silvia S Martins, Edward W Boyer, Robert G Carlson
BACKGROUND: "Rosin tech" is an emerging solventless method consisting in applying moderate heat and constant pressure on marijuana flowers to prepare marijuana concentrates referred to as "rosin." This paper explores rosin concentrate-related Twitter data to describe tweet content and analyze differences in rosin-related tweeting across states with varying cannabis legal statuses. METHOD: English language tweets were collected between March 15, 2015 and April 17, 2017, using Twitter API...
December 27, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29306378/an-evaluation-of-the-educational-requirements-to-practise-radiography-in-the-european-union
#9
J G Couto, S McFadden, P Bezzina, P McClure, C Hughes
INTRODUCTION: Radiography is practised world wide, however, the definition of the profession varies across countries. As there is no regulation of the profession or education at EU level, different national regulations might result in educational differences that can compromise the movement of professionals or the safety of patients. The aim of this study was to identify the commonalities and discrepancies in national regulation of radiography. METHODS: National competent authorities from all EU countries where the profession is regulated (n = 27) were invited to identify the legal requirements to practise radiography and the data was analysed using thematic analysis...
February 2018: Radiography
https://www.readbyqxmd.com/read/29302196/when-good-times-go-bad-managing-legal-high-complications-in-the-emergency-department
#10
REVIEW
Charles R Caffrey, Patrick M Lank
Patients can use numerous drugs that exist outside of existing regulatory statutes in order to get "legal highs." Legal psychoactive substances represent a challenge to the emergency medicine physician due to the sheer number of available agents, their multiple toxidromes and presentations, their escaping traditional methods of analysis, and the reluctance of patients to divulge their use of these agents. This paper endeavors to cover a wide variety of "legal highs," or uncontrolled psychoactive substances that may have abuse potential and may result in serious toxicity...
2018: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/29301148/current-perspectives-on-biotechnological-cannabinoid-production-in-plants
#11
Julia Schachtsiek, Heribert Warzecha, Oliver Kayser, Felix Stehle
The plant Cannabis sativa contains a number of psychoactive chemical compounds, the cannabinoids, which possess a significant pharmaceutical potential. Recently, the usage of Cannabis for medicinal purposes was legalized in many countries. Thus, the study on the influence of different cannabinoids in combination with other Cannabis-derived compounds with respect to the treatment of various diseases becomes increasingly important. Besides the production of distinct cannabinoids in a heterologous host, like tobacco or yeast, transgenic Cannabis plants would be a suitable alternative to modify and therefore optimize the cannabinoid profile...
January 4, 2018: Planta Medica
https://www.readbyqxmd.com/read/29296130/driving-and-dementia-workshop-module-on-communicating-cessation-to-drive
#12
Anna Byszewski, Barbara Power, Linda Lee, Glara Gaeun Rhee, Bob Parson, Frank Molnar
Background: For persons with dementia (PWD), driving becomes very dangerous. Physicians in Canada are legally responsible to report unfit drivers and then must disclose that decision to their patients. That difficult discussion is fraught with challenges: physicians want to maintain a healthy relationship; patients often lack insight into their cognitive loss and have very strong emotional reactions to the loss of their driving privileges. All of which may stifle the exchange of accurate information...
December 2017: Canadian Geriatrics Journal: CGJ
https://www.readbyqxmd.com/read/29294707/physical-violence-against-children-and-adolescents-in-porto-a-5-year-study
#13
Humberto Gomes Vidal, Inês Morais Caldas, Arnaldo de França Caldas, Luiz Gutenberg Toledo de Miranda Coelho Júnior, Eliane Helena Alvim de Souza, Maria Lurdes Pereira
The aim of the present study was to analyze the prevalence of physical violence against children and adolescents (PVCA) in a 5-year period in the city of Porto, Portugal. All forensic reports between 2009 and 2013 in the clinical services of the North Branch of the National Institute of Legal Medicine and forensic sciences were analyzed. Victims were classified according to sex, age, relationship with perpetrator, traumatic consequences of the event, and year of occurrence. Statistical analysis was performed using SPSS (Version 22...
April 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29284138/psychiatry-the-psychedelic-drugs-past-present-future
#14
REVIEW
James J H Rucker, Jonathan Iliff, David J Nutt
The classical psychedelic drugs, including psilocybin, lysergic acid diethylamide and mescaline, were used extensively in psychiatry before they were placed in Schedule I of the UN Convention on Drugs in 1967. Experimentation and clinical trials undertaken prior to legal sanction suggest that they are not helpful for those with established psychotic disorders and should be avoided in those liable to develop them. However, those with so-called 'psychoneurotic' disorders sometimes benefited considerably from their tendency to 'loosen' otherwise fixed, maladaptive patterns of cognition and behaviour, particularly when given in a supportive, therapeutic setting...
December 25, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29283643/-let-s-get-in-formation-on-becoming-a-psychologist-activist-in-the-21st-century
#15
Kevin L Nadal
Throughout the history of the United States, there have been many social movements that have resulted in an array of historic societal outcomes-ranging from the end of racial segregation to women's voting rights to the legalization of same-sex marriages. Despite the positive outcomes derived from political activism, many psychologists have struggled with how to advocate for social justice while maintaining their professional responsibilities and ethical boundaries. The current article reviews the historical ways that psychologists have participated in political movements-from the use of psychological research in landmark U...
December 2017: American Psychologist
https://www.readbyqxmd.com/read/29277174/characteristics-of-managed-entry-agreements-in-australia
#16
Maxine F Robinson, Cathrine Mihalopoulos, Tracy Merlin, Elizabeth Roughead
OBJECTIVES: Australia relies on managed entry agreements (MEAs) for many medicines added to the national Pharmaceutical Benefits Scheme (PBS). Previous studies of Australian MEAs examined public domain documents and were not able to provide a comprehensive assessment of the types and operation of MEAs. This study used government documents approved for release to examine the implementation and administration of MEAs implemented January 2012 to May 2016. METHODS: We accessed documents for medicines with MEAs on the PBS between January 2012 and May 2016...
December 26, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29273824/accuracy-of-the-third-molar-maturity-index-in-assessing-the-legal-age-of-18%C3%A2-years-a-systematic-review-and-meta-analysis
#17
Bianca Marques Santiago, Leopoldina Almeida, Yuri Wanderley Cavalcanti, Marcela Baraúna Magno, Lucianne Cople Maia
The age estimation is a complex procedure required in the daily practice of legal medicine. The maturity of third molars stands out by the age of 18 because these teeth are still in development. This systematic review aimed to assess the accuracy of the third molar maturity index (I 3M), proposed by Cameriere et al. (2008), in discriminating whether an individual is under or over 18 years. Seven electronic databases were screened: PubMed, Scopus, ISI Web of Science, Cochrane Library, LILACS, SIGLE, and CAPES...
December 22, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29247863/becoming-a-medical-marijuana-user
#18
Stephen E Lankenau, Avat Kioumarsi, Megan Reed, Miles McNeeley, Ellen Iverson, Carolyn F Wong
BACKGROUND: Since marijuana became legal for medical use in California in 1996, reasons for medical use among medical marijuana patients (MMP) have become increasingly well described in qualitative studies. However, few studies have detailed how the use of marijuana for medical purposes fits into the broader career trajectories of either becoming a marijuana user or becoming a MMP, including the social influences on medical use. METHODS: Young adult MMP (N=40) aged 18 to 26 years old were recruited in Los Angeles, CA in 2014-15 and administered a semi-structured interview that included questions focusing on marijuana use practices before and after becoming MMP...
December 13, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29247094/oral-medicine-modification-for-older-adults-a-qualitative-study-of-nurses
#19
Aoife Mc Gillicuddy, Abina M Crean, Maria Kelly, Laura Sahm
OBJECTIVE: Oral medicines are frequently modified (eg, tablets crushed) for older adults. However, these modifications can have clinical, legal and/or ethical implications. Nurses bear responsibility for medicine administration and hence, perform these modifications. The aim of this study was to investigate the knowledge, attitudes and beliefs of nurses about oral medicine modification for older adults. DESIGN: A qualitative study was conducted using semi-structured, face-to-face interviews with nurses providing care to older adults in acute and long-term care settings...
December 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29233952/epidemiological-study-of-mortality-rate-from-alcohol-and-illicit-drug-abuse-in-iran
#20
Seyed Mohammad Sadegh Ghoreishi, Fatemeh Shahbazi, Seyed Davood Mirtorabi, Mohammad Reza Ghadirzadeh, Seyed Saeed Hashemi Nazari
BACKGROUND: The estimate of mortality associated with illicit opiate use provides useful information to those directing and monitoring local, national and international policies and programs. This study investigated the epidemiology of mortality due to the illegal consumption of narcotics and psychotropic substances in the Iran to provide evidence-based public health data for useful programs and actions aimed at preventing drug-related mortality. STUDY DESIGN: A cross-sectional study...
October 14, 2017: Journal of Research in Health Sciences
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