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https://www.readbyqxmd.com/read/28633386/oral-administration-of-tea-saponins-to-relive-oxidative-stress-and-immune-suppression-in-chickens
#1
X Chi, S Bi, W Xu, Y Zhang, S Liang, S Hu
The present study was designed to evaluate the effects of tea saponins on oxidative stress induced by cyclophosphamide in chickens. One hundred twenty chickens were randomly divided into 5 groups. Groups 3 to 4 received intramuscular injection of cyclophosphamide to induce oxidative stress and immunosuppression. After that, groups 2 and 4 were orally administered tea saponins in drinking water for 7 d. Then, groups 1 to 4 were immunized with a live, bivalent vaccine of Newcastle disease virus and infectious bronchitis virus...
June 15, 2017: Poultry Science
https://www.readbyqxmd.com/read/28624261/dutch-health-websites-and-their-ability-to-inform-people-with-low-health-literacy
#2
Corine S Meppelink, Julia C M van Weert, Anna Brosius, Edith G Smit
OBJECTIVE: To evaluate whether Dutch online health information (OHI) generally reflects message elements that support information processing and understanding among people with low health literacy. METHODS: We content-analyzed one hundred Dutch webpages about Ebola, fibromyalgia, ALS, losing weight, borderline personality disorder, hemorrhoids, ADD, bladder infection, shingles, and chicken pox. The codebook covered the following domains: images and videos, readability level, Suitability Assessment of Materials (SAM), advertising, interactive features, and reliability cues...
June 10, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28620135/ammonium-glycyrrhizin%C3%A2-counteracts-liver-injury-caused-by-lipopolysaccharide-amoxicillin-clavulanate-potassium
#3
Zugong Yu, Feng Wu, Jing Tian, Xuewen Guo, Ran An, Yangyang Guo
We treated isolated chicken primary hepatocytes with lipopolysaccharide/amoxicillin clavulanate potassium (LPS/AC) to model liver injury and investigate its underlying mechanisms. We also used this model to assess the cytoprotective effects of compound ammonium glycyrrhizin (CAG) in vitro. LPS/AC-induced injury decreased cell viability and increased the activity of serum aspartate transaminase and alanine transaminase. Levels of superoxide dismutase, glutathione, and glutathione peroxidase were lower than control, while levels of the oxidative product malondialdehyde and reactive oxygen species were higher...
May 30, 2017: Oncotarget
https://www.readbyqxmd.com/read/28618762/antiinflammatory-and-antioxidant-effects-of-gemcitabine-in-collagen-induced-arthritis-model
#4
Adile Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Metin Özgen, Kazım Şahin, Süleyman Serdar Koca
BACKGROUND/AIM: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on collagen-induced arthritis (CIA). MATERIALS AND METHODS: Arthritis was induced by the intradermal injection of chicken type II collagen with incomplete Freund's adjuvant into albino Wistar rats. Doses of 5 and 20 mg/kg GEM were administered twice a week after the 14th day, which marked the onset the arthritis...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28516388/effects-of-different-selenium-sources-on-growth-performance-antioxidant-capacity-and-meat-quality-of-local-chinese-subei-chickens
#5
J L Li, L Zhang, Z Y Yang, Z Y Zhang, Y Jiang, F Gao, G H Zhou
Despite increasing evidence indicating the essential involvement of selenium (Se) on growth performance, antioxidant capacity, and meat quality of commercial broilers, the effects of different Se sources on local Chinese Subei chickens is unclear. A total of 360 50-day-old male chickens were individually weighed and randomly allocated to four treatment groups. Chickens in each of the four groups were fed diets supplemented with 0.3 mg Se/kg as sodium Se (SS), Se-enriched yeast (SY), selenomethionine (Met-Se), or nano red element Se (Nano-Se) for 40 days...
May 17, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28432527/effects-of-agaricus-blazei-murill-polysaccharide-on-cadmium-poisoning-on-the-mda5-signaling-pathway-and-antioxidant-function-of-chicken-peripheral-blood-lymphocytes
#6
Ai Lv, Ming Ge, Xuequan Hu, Wenjing Liu, Guangxing Li, Ruili Zhang
This experimental study investigated the effect of Agaricus blazei Murill polysaccharide (ABP) on cadmium (Cd) poisoning on the melanoma differentiation-associated gene 5 (MDA5) signaling pathway and antioxidant function of peripheral blood lymphocytes (PBLs) in chickens. The experiments were divided into four groups: 7-day-old chickens with normal saline (0.2 mL single/day), Cd (140 mg/kg), ABP (30 mg/mL, 0.2 mL single/day), and Cd + ABP(140 mg/kg/day + 0.2 mL ABP). Peripheral blood was collected on the 20th, 40th, and 60th days for each group, and PBLs were separated...
April 21, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28412990/influence-of-pre-storage-incubation-on-hatchability-traits-thyroid-hormones-antioxidative-status-and-immunity-of-newly-hatched-chicks-at-two-chicken-breeder-flock-ages
#7
T A Ebeid, F A Twfeek, M H Assar, A M Bealish, R E Abd El-Karim, M Ragab
Egg storage longer than 7 days is associated with negative effects on hatchability traits. Pre-storage incubation has been a suggested method to reduce the negative effects of long-term storage times by enhancing the developmental stage of the embryo and probably reducing the embryonic stress. The objective of the present study was to investigate the effects of pre-storage incubation and storage time on hatchability characteristics, chick quality and serum thyroid hormones, antioxidative properties and immunoglobulin Y (IgY) concentrations of newly hatched chicks at two breeder flock ages...
April 17, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28409411/attenuating-effect-of-zinc-and-vitamin-e-on-the-intestinal-oxidative-stress-induced-by-silver-nanoparticles-in-broiler-chickens
#8
Zhigang Song, Jiadong Lv, Ardashir Sheikhahmadi, Julie Uerlings, Nadia Everaert
Silver nanoparticles (AgNPs) have been increasingly used as antimicrobial and disinfectant. However, intestinal model studies have shown that AgNPs induce oxidative stress. Hence, this study aims to investigate the effects of dietary supplemental zinc (Zn) and vitamin E (VE; α-tocopherol acetate) on attenuating AgNP-induced intestinal oxidative stress in broiler chickens. The chickens were divided into two groups as follows: (1) control group fed with a corn-soybean meal basal diet and (2) nano group, received drinking water containing 1000 mg/kg AgNPs...
April 14, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28408118/a-novel-combined-vaccine-based-on-monochimeric-vlp-co-displaying-multiple-conserved-epitopes-against-enterovirus-71-and-varicella-zoster-virus
#9
Yangtao Wu, Rui Zhu, Longfa Xu, Yongchao Li, Shuxuan Li, Hai Yu, Shaowei Li, Hua Zhu, Tong Cheng, Ningshao Xia
Chicken pox and hand, foot and mouth disease (HFMD) are two major infectious diseases that mainly affect infants and children, causing significant morbidity annually. Varicella-zoster virus (VZV) and enterovirus 71 (EV71), respectively, are the principal epidemic pathogens causing these two diseases. To investigate the possibility of developing a novel combined vaccine to prevent chicken pox and HFMD, we constructed three chimeric virus-like particles (VLPs) (termed HBc-V/1/2, HBc-2/V/1 and HBc-1/2/V) based on the hepatitis B core antigen (HBc) carrier that display epitopes derived from VZV-gE, EV71-VP1, and EV71-VP2 in a varied tandem manner...
May 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28367398/varicella-zoster-virus-glycoproteins-entry-replication-and-pathogenesis
#10
Stefan L Oliver, Edward Yang, Ann M Arvin
Varicella-zoster virus (VZV), an alphaherpesvirus that causes chicken pox (varicella) and shingles (herpes zoster), is a medically important pathogen that causes considerable morbidity and, on occasion, mortality in immunocompromised patients. Herpes zoster can afflict the elderly with a debilitating condition, postherpetic neuralgia, triggering severe, untreatable pain for months or years. The lipid envelope of VZV, similar to all herpesviruses, contains numerous glycoproteins required for replication and pathogenesis...
December 2016: Current Clinical Microbiology Reports
https://www.readbyqxmd.com/read/28367146/lack-of-evidence-that-selenium-yeast-improves-chicken-health-and-modulates-the-caecal-microbiota-in-the-context-of-colonization-by-campylobacter-jejuni
#11
Alexandre Thibodeau, Ann Letellier, Étienne Yergeau, Guillaume Larrivière-Gauthier, Philippe Fravalo
Faced with ever-increasing demand, the industrial production of food animals is under pressure to increase its production. In order to keep productivity, quality, and safety standards up while reducing the use of antibiotics, farmers are seeking new feed additives. In chicken production, one of these additives is selenium. This element is expected to confer some advantages in terms of animal health and productivity, but its impact on chicken intestinal microbiota as well as on the carriage of foodborne pathogens is unknown...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28295656/effect-of-dietary-polyphenol-rich-grape-seed-on-growth-performance-antioxidant-capacity-and-ileal-microflora-in-broiler-chicks
#12
S H Abu Hafsa, S A Ibrahim
In this study, we examined the effect of dietary supplementation with grape seed (GS) on the performance, carcass traits, plasma biochemistry, antioxidant status and ileal microflora in broilers. Experiment diets included a control diet (without additive) and three levels of GS powder (10, 20 and 40 g/kg of diet). Each diet was fed to a total of 300 one-day-old Cobb-500 chicks for 42 days. The addition of 20 g/kg of GS to the basal diet increased final body weight and body weight gain, improved the feed conversion ratio and did not affect feed intake...
March 15, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28287424/keloid-and-hypertrophic-scars-are-the-result-of-chronic-inflammation-in-the-reticular-dermis
#13
REVIEW
Rei Ogawa
Keloids and hypertrophic scars are caused by cutaneous injury and irritation, including trauma, insect bite, burn, surgery, vaccination, skin piercing, acne, folliculitis, chicken pox, and herpes zoster infection. Notably, superficial injuries that do not reach the reticular dermis never cause keloidal and hypertrophic scarring. This suggests that these pathological scars are due to injury to this skin layer and the subsequent aberrant wound healing therein. The latter is characterized by continuous and histologically localized inflammation...
March 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28251482/analysis-of-the-interactions-between-thioredoxin-and-20-selenoproteins-in-chicken
#14
Qi Liu, Jie Yang, Jingzeng Cai, Yilin Luan, Hamid Sattar, Man Liu, Shiwen Xu, Ziwei Zhang
Thioredoxin (Trx) is a small molecular protein with complicated functions in a number of processes, including inflammation, apoptosis, embryogenesis, cardiovascular disease, and redox regulation. Some selenoproteins, such as glutathione peroxidase (Gpx), iodothyronine deiodinase (Dio), and thioredoxin reductase (TR), are involved in redox regulation. However, whether there are interactions between Trx and selenoproteins is still not known. In the present paper, we used a Modeller, Hex 8.0.0, and the KFC2 Server to predict the interactions between Trx and selenoproteins...
March 2, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28235456/detection-of-histidine-rich-glycoprotein-and-fibrinogen-with-nickel-enzyme-conjugates-purification-of-rabbit-hrg
#15
COMPARATIVE STUDY
Mathia Colwell, Najma Ahmed, Ralph Butkowski
Nickel-bound alkaline phosphatase and peroxidase enzymes were used to investigate nickel binding to plasma proteins. Rabbit plasma dilutions to 25,000 were positive by ELISA, while Western blot analysis showed a prominent reaction with histidine-rich glycoprotein (HRG)(1) and lower reaction with fibrinogen (Fgn). To confirm their identities, purified HRG and Fgn were demonstrated to react with the nickel-bound enzymes by Western analysis. With disulfide bonds reduced, HRG and Fgn α-chain reactions were demonstrated...
May 15, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28228180/age-related-oxidative-stress-and-antioxidant-capacity-in-heat-stressed-broilers
#16
A P Del Vesco, A S Khatlab, E S R Goes, K S Utsunomiya, J S Vieira, A R Oliveira Neto, E Gasparino
We aimed to evaluate the effects of acute heat stress (HS) and age on the redox state in broilers aged 21 and 42 days. We evaluated the expression of genes related to antioxidant capacity, the production of hydrogen peroxide (H2O2), and the activity of antioxidant enzymes in the liver, as well as oxidative stress markers in the liver and plasma. The experiment had a completely randomized factorial design with two thermal environments (thermoneutral and HS, 38°C for 24 h) and two ages (21 and 42 days). Twenty-one-day-old animals exposed to HS showed the highest thioredoxin reductase 1 (TrxR1) (P<0...
February 23, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28140330/insights-for-setting-of-nutrient-requirements-gleaned-by-comparison-of-selenium-status-biomarkers-in-turkeys-and-chickens-versus-rats-mice-and-lambs
#17
REVIEW
Roger A Sunde, Jin-Long Li, Rachel M Taylor
To gain insights into nutrient biomarkers and setting of dietary nutrient requirements, selenium biomarker levels and requirements in response to multiple graded levels of dietary selenium were compared between day-old turkeys and chickens versus weanling rats and mice and 2-d-old lambs supplemented with sodium selenite. In rodents, there was no significant effect of dietary selenium on growth, indicating that the minimum selenium requirement was <0.007 μg Se/g diet. In contrast, there was a significant effect in turkeys, chicks, and lambs, which showed selenium requirements for growth of 0...
November 2016: Advances in Nutrition
https://www.readbyqxmd.com/read/28116627/alleviation-of-lead-induced-oxidative-stress-and-immune-damage-by-selenium-in-chicken-bursa-of-fabricius
#18
Xiaoyan Jiao, Kai Yang, Yang An, Xiaojie Teng, Xiaohua Teng
We investigated lead (Pb)-induced oxidative stress and immune damage in the chicken bursa of Fabricius (BF) and the ameliorative effect of selenium (Se). Seven-day-old male chickens were randomly divided into four groups and were provided standard diet and drinking water, Na2SeO3 added to the standard diet and drinking water, standard diet and (CH3COO)2Pb added to drinking water, and Na2SeO3 added to the standard diet and (CH3COO)2Pb added to drinking water for 30, 60, and 90 days. The presence of Pb inhibited total antioxidant capacity (T-AOC), glutathione peroxidase (GPx), glutathione S-transferase (GST), superoxide dismutase (SOD), and catalase (CAT) activities; decreased glutathione (GSH) content; increased malondialdehyde (MDA) and hydrogen peroxide (H2O2) contents; inhibited interleukin (IL)-2 and interferon-γ (IFN-γ) messenger RNA (mRNA) expression; and increased IL-4, IL-6, IL-10, IL-12β, and IL-17 mRNA expression...
March 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28096619/detection-identification-and-differentiation-of-sheep-pox-virus-and-goat-pox-virus-from-clinical-cases-in-giza-governorate-egypt
#19
M A Mahmoud, M H Khafagi
AIM: To isolate, identify, and differentiate Capripoxviruses (CaPV) (sheep pox virus and goat pox virus) infections by egg inoculation, transmission electron microscopy (TEM), and 30 kDa RNA polymerase subunit gene-based polymerase chain reaction (PCR) (RPO30) in clinically affected animals in Hawamdia township of Giza Governorate, Egypt. MATERIALS AND METHODS: A total of 37 scab samples were collected from clinically suspected field cases of sheep pox and goat pox...
December 2016: Veterinary World
https://www.readbyqxmd.com/read/28088013/delineating-hierarchy-of-selenotranscriptome-expression-and-their-response-to-selenium-status-in-chicken-central-nervous-system
#20
Xiu-Qing Jiang, Chang-Yu Cao, Zhao-Yang Li, Wei Li, Cong Zhang, Jia Lin, Xue-Nan Li, Jing-Long Li
Selenium (Se) incorporated in selenoproteins as selenocysteine and supports various important cellular and organismal functions. We recently reported that chicken brain exhibited high priority for Se supply and retention under conditions of dietary Se deficiency and supernutrition Li et al. (2012) . However, the selenotranscriptome expressions and their response to Se status in chicken central nervous system (CNS) are unclear. To better understand the relationship of Se homeostasis and selenoproteins expression in chicken CNS, 1day-old HyLine White chickens were fed a low Se diet (Se-L, 0...
April 2017: Journal of Inorganic Biochemistry
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