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https://www.readbyqxmd.com/read/29136306/patient-and-physician-satisfaction-in-an-observational-study-with-methyl-aminolevulinate-daylight-photodynamic-therapy-in-the-treatment-of-multiple-actinic-keratoses-of-the-face-and-scalp-in-6-european-countries
#1
M C Fargnoli, S H Ibbotson, R E Hunger, G Rostain, M T W Gaastra, L Eibenschutz, C Cantisani, A W Venema, S Medina, N Kerrouche, B Pérez-Garcia
BACKGROUND: Guidelines recommend treating actinic keratoses (AK) as they are recognized as precursors of invasive squamous cell carcinoma. OBJECTIVE: The objective of this study was to collect real-world clinical data on the use of methyl aminolevulinate daylight-photodynamic therapy (MAL DL-PDT) for the treatment of face and scalp AK in Europe. METHODS: A prospective, multicenter, non-interventional study was conducted in 6 European countries in patients receiving a single treatment of MAL DL-PDT for face and/or scalp AK...
November 14, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29106837/evaluation-of-industrial-compensation-to-cardiologists-in-2015
#2
Muhammad Shahzeb Khan, Tariq Jamal Siddiqi, Kaneez Fatima, Haris Riaz, Faisal Khosa, Warren J Manning, Richard Krasuski
The categorization and characterization of pharmaceutical and device manufacturers or group purchasing organization payments to clinicians is an important step toward assessing conflicts of interest and the potential impact of these payments on practice patterns. Payments have not previously been compared among the subspecialties of cardiology. This is a retrospective analysis of the Open Payments database, including all installments and payments made to doctors in the calendar year 2015 by pharmaceutical and device manufacturers or group purchasing organization...
September 19, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29069076/childhood-stunting-in-relation-to-the-pre-and-postnatal-environment-during-the-first-2-years-of-life-the-mal-ed-longitudinal-birth-cohort-study
#3
(no author information available yet)
BACKGROUND: Stunting is the most prevalent manifestation of childhood malnutrition. To characterize factors that contribute to stunting in resource-poor settings, we studied a priori selected biological and social factors collected longitudinally in a cohort of newborns. METHODS AND FINDINGS: We enrolled 1,868 children across 7 resource-poor settings in Bangladesh, Brazil, India, Nepal, Peru, South Africa, and Tanzania shortly after birth and followed them for 24 months between 2 November 2009 and 28 February 2014...
October 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29037267/tracking-of-infant-and-young-child-feeding-practices-among-9-to-24-month-old-children-in-nepal-the-mal-ed-birth-cohort-study
#4
Marianne S Morseth, Liv Elin Torheim, Mekdes K Gebremariam, Ram K Chandyo, Manjeswori Ulak, Sanjaya K Shrestha, Binob Shrestha, Sigrun Henjum
OBJECTIVE: The present study aimed to assess infant and young child feeding (IYCF) practices and the tracking of dietary diversity score (DDS), intakes of Fe- and vitamin A-rich foods and meal frequency in a peri-urban area in Nepal. Furthermore, to explore whether sociodemographic factors were associated with tracking patterns of these IYCF practices. DESIGN: Longitudinal study. Monthly food intake was measured by 24 h recall. Four time slots were used (9-12, 13-16, 17-20 and 21-24 months)...
October 17, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28958169/recommendations-for-infant-feeding-policy-and-programs-in-dzimauli-region-south-africa-results-from-the-mal-ed-birth-cohort
#5
Lindelani Fhumudzani Mushaphi, Tjale Cloupas Mahopo, Cebisa Noxolo Nesamvuni, Brenda Baloyi, Ellen Mashau, Jeniata Richardson, Rebecca Dillingham, Richard Guerrant, Ramya Ambikapathi, Pascal Bessong
BACKGROUND: There is strong evidence that exclusive breastfeeding (EBF) in the first 6 months of life reduces the risk of diseases in infancy and in later life. OBJECTIVE: To understand the maternal reasoning that influences optimum infant feeding practices of caregivers in semirural communities of Limpopo province. METHODS: Nested qualitative study among mothers in an ongoing birth cohort study was conducted; structured and semi-structured interviews were used to collect data...
September 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28905294/high-patient-satisfaction-with-daylight-activated-methyl-aminolevulinate-cream-in-the-treatment-of-multiple-actinic-keratoses-results-of-an-observational-study-in-australia
#6
Jo-Ann See, Kurt Gebauer, Jason K Wu, Shobhan Manoharan, Nabil Kerrouche, John Sullivan
INTRODUCTION: Actinic keratoses (AK) are treated to reduce the risk of progression to squamous cell carcinoma and for symptomatic and cosmetic benefits. The objective of this observational study was to generate real-life data on the use of daylight photodynamic therapy with methyl aminolevulinate cream (MAL DL-PDT) in treating mild to moderate facial/scalp AK. METHODS: A multicenter, prospective, observational study was conducted in Australia in patients receiving a single treatment of MAL DL-PDT for mild to moderate AK...
December 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28893223/brca2-carriers-with-male-breast-cancer-show-elevated-tumour-methylation
#7
Siddhartha Deb, Kylie L Gorringe, Jia-Min B Pang, David J Byrne, Elena A Takano, kConFab Investigators, Alexander Dobrovic, Stephen B Fox
BACKGROUND: Male breast cancer (MBC) represents a poorly characterised group of tumours, the management of which is largely based on practices established for female breast cancer. However, recent studies demonstrate biological and molecular differences likely to impact on tumour behaviour and therefore patient outcome. The aim of this study was to investigate methylation of a panel of commonly methylated breast cancer genes in familial MBCs. METHODS: 60 tumours from 3 BRCA1 and 25 BRCA2 male mutation carriers and 32 males from BRCAX families were assessed for promoter methylation by methylation-sensitive high resolution melting in a panel of 10 genes (RASSF1A, TWIST1, APC, WIF1, MAL, RARβ, CDH1, RUNX3, FOXC1 and GSTP1)...
September 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28782337/diagnosis-management-and-prevention-of-hepatitis-c-in-pakistan-2017
#8
Muhammad Umar, Hamama-Tul-Bushra Khaar, Tayyab Saeed Akhter, Faiza Aslam, Syed Irfan Ahmad, Rai Mohammad Asghar, Mohammad Khurram, Tassawar Hussain, Amjad Salamat, Anwar A Khan, Fazal-E-Hadi, Zahid Mahmood Minhas, Hasnain Ali Shah, Javed Farooqui, Asif Abbas Naqvi, Aftab Mohsin, Waseem-Ud-Din, Sohail Iqbal Bhutta, Sibt Ul Hasnain Syed, Saleem Qureshi, Tashfeen Adam, Moazzam Uddin, Ghias-U-Nabi Tayyab, Najeeb Ul Haq, Atifa Shoaib, Saima Ambreen, Arslan Shahzad, Nadeem Ikram, Gul Nisar, Mohammad Mujeeb Khan, Mohammad Osama
Aims and Objectives: Since the advent of direct acting antiviral agents, there is a revolutionary change in the management of HCV infection. Newer drugs with different mechanism of action are being introduced and are expected to be available in coming few months in Pakistan as well. The main purpose of the guideline is to review and induct the latest research in field of HCV infection in Pakistani perspective so that our healthcare professionals can apply the new recommendations in timely and judicial manner...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28719336/infant-nutritional-status-feeding-practices-enteropathogen-exposure-socioeconomic-status-and-illness-are-associated-with-gut-barrier-function-as-assessed-by-the-lactulose-mannitol-test-in-the-mal-ed-birth-cohort
#9
Gwenyth O Lee, Benjamin J J McCormick, Jessica C Seidman, Margaret N Kosek, Rashidul Haque, Maribel Paredes Olortegui, Aldo A M Lima, Zulfiqar A Bhutta, Gagandeep Kang, Amidou Samie, Caroline Amour, Carl J Mason, Tahmeed Ahmed, Pablo Peñataro Yori, Domingos B Oliveira, Didar Alam, Sudhir Babji, Pascal Bessong, Estomih Mduma, Sanjaya K Shrestha, Ramya Ambikapathi, Dennis R Lang, Michael Gottlieb, Richard L Guerrant, Laura E Caulfield, For The Mal-Ed Network Investigators
The lactulose mannitol (LM) dual sugar permeability test is the most commonly used test of environmental enteropathy in developing countries. However, there is a large but conflicting literature on its association with enteric infection and host nutritional status. We conducted a longitudinal cohort using a single field protocol and comparable laboratory procedures to examine intestinal permeability in multiple, geographically diverse pediatric populations. Using a previously published systematic review to guide the selection of factors potentially associated with LM test results, we examined the relationships between these factors and mucosal breach, represented by percent lactulose excretion; absorptive area, represented by percent mannitol excretion; and gut barrier function, represented by the L/M ratio...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28611900/replacement-of-dislodged-gastrostomy-tubes-after-stoma-dilation-in-the-pediatric-emergency-department
#10
Shiloni Bhambani, Tammy H Phan, Lance Brown, Andrea W Thorp
INTRODUCTION: A dislodged gastrostomy tube (GT) is a common complaint that requires evaluation in the pediatric emergency department (ED) and, on occasion, will require stoma dilation to successfully replace the GT. The objective of this study was to describe the frequency that stoma dilation is required, the success rate of replacement, complications encountered, and the techniques used to confirm placement of the GT after dilation. METHODS: We conducted a retrospective medical record review of children 0-18 years who presented to the pediatric ED from February 2013 through February 2015 with a dislodged GT that required stoma dilation by pediatric emergency physicians with serially increasing Foley catheter sizes prior to successful placement of the GT...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28573783/towards-a-science-and-practice-of-resilience-in-the-face-of-pain
#11
REVIEW
L Goubert, H Trompetter
The primary objective of this paper is to discuss how a resilience approach to (chronic) pain may advance our current understanding of (mal)adaptation to pain. Different resilience perspectives are described, and future challenges for research, prevention and treatment of (chronic) pain are discussed. Literature searches were performed in Web of Science and PubMed to identify relevant literature on risk and resilience in the context of pain. Resilience can be best defined as the ability to restore and sustain living a fulfilling life in the presence of pain...
September 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28460757/our-intellectuals-have-failed-us-system-of-a-down
#12
EDITORIAL
Sundeep Mishra
Medical profession is at cross-roads. On one hand are issues like medical mal-practice and negligence but on the other are loss of respect, low re-imbursement, lawsuits against medical professionals, violence against physicians all contributing to a lot of stress as also a high suicide rate among medical practitioners. While some of the problems seem related to changing societal norms, most of them seem to stem from a failure, active or passive on the part of medical intellectual, moving away from altruism, justice and self regulation to pursuance of self interest with a consequent loss of trust in doctor-patient relationship...
March 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28383850/-the-school-doctorand-suspected-child-abuse-towards-good-practice-recommendations-in-the-child-s-interest
#13
REVIEW
F Noirhomme-Renard, A Blavier, S Lachaussée, C Monville, C Nihoul, C Gosset
Child maltreatment, including all forms of mal¬treatment, remains a major public health problem in high-income countries. Healthcare professionals only contribute to a small proportion of reports. In French-speaking Belgium, almost 100 % of school-aged children are regularly submitted to periodical school health visits. The school health doctor is well placed to recognize neglected or abused children. Based on international good practice recommendations, this paper proposes means for the detection and management of child abuse in the context of school medicine...
October 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28360880/-mal-adaptive-psychological-functioning-of-students-utilizing-university-counseling-services
#14
Valeria Biasi, Rita Cerutti, Luca Mallia, Francesca Menozzi, Nazarena Patrizi, Cristiano Violani
Background: University students confront psychological difficulties that can negatively influence their academic performance. The present study aimed to assess several areas of adaptive and maladaptive psychological functioning among university students who request counseling services. Method: One hundred eighty-four young female students seeking professional psychological help (Counseling seekers) and 185 young female students who have never asked for psychological help (Non-counseling seekers) were asked to complete the Adult Self-Report (ASR) to evaluate both their internalizing and externalizing problems through DSM-oriented scales as well as their adaptive functioning...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28318153/-dental-alveolar-bone-and-dental-arch-remodeling-in-children-orthodontic-diagnosis-and-treatments-based-on-individual-child-arch-development
#15
Li Xiaobing
The etiology of malocclusions basically involves both congenital and environmental factors. Malocclusion is the result of the abnormal development of the orofacial complex (including tooth, dental alveolar bone, upper and lower jaws). Early orthodontic interceptive treatments involve the elimination of all congenital and environmental factors that contribute to the malformation of the orofacial complex, as well as interrupt the deviated development of the orofacial complex and the occlusion. Early orthodontic interceptive treatments mainly aim to use children's growth potential to correct abnormal developments of occlusions and orthodontically treat malocclusions more efficiently...
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28079114/discovering-potential-serological-biomarker-for-chronic-hepatitis-b-virus-related-hepatocellular-carcinoma-in-chinese-population-by-mal-associated-serum-glycoproteomics-analysis
#16
Tianhua Liu, Denghe Liu, Riqiang Liu, Hucong Jiang, Guoquan Yan, Wei Li, Lu Sun, Shu Zhang, Yinkun Liu, Kun Guo
The accuracy of current biomarkers for the diagnosis of hepatocellular carcinoma (HCC), especially chronic Hepatitis B Virus (HBV)-related HCC, is limited. Recent progress in glycoproteomics has provided a novel platform for screening novel serological biomarkers of HCC. In this study, lectin affinity chromatography by Maackia amurensis lectin (MAL) and iTRAQ combined with mass spectrometric analysis were performed to enrich and identify the glycoprotein fractions in serum samples from HBV-related HCC patients and from healthy controls...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28042933/teaching-peritoneal-dialysis-in-australia-an-opportunity-for-improvement
#17
N Boudville, Y Cho, K L Equinox, A E Figueiredo, C M Hawley, K Howard, D W Johnson, M Jose, A Lee, Mal Maley, J Moodie, E M Pascoe, G Z Steiner, M Tomlins, D Voss, J Chow
INTRODUCTION: Up to a 10-fold difference in clinical outcomes between Australian peritoneal dialysis (PD) units exists. There is an international focus on the harmonisation of educational practices in PD to determine whether this may lead to improved patient outcomes. AIMS: Evaluate the current teaching practices of nurses and patients in Australian PD units. METHODS: An online survey with questions on nurse and patient training was made available to PD units in Australia...
January 2, 2017: Nephrology
https://www.readbyqxmd.com/read/27994110/dynamics-and-trends-in-fecal-biomarkers-of-gut-function-in-children-from-1-24-months-in-the-mal-ed-study
#18
Benjamin J J McCormick, Gwenyth O Lee, Jessica C Seidman, Rashidul Haque, Dinesh Mondal, Josiane Quetz, Aldo A M Lima, Sudhir Babji, Gagandeep Kang, Sanjaya K Shrestha, Carl J Mason, Shahida Qureshi, Zulfiqar A Bhutta, Maribel Paredes Olortegui, Pablo Peñataro Yori, Amidou Samie, Pascal Bessong, Caroline Amour, Estomih Mduma, Crystal L Patil, Richard L Guerrant, Dennis R Lang, Michael Gottlieb, Laura E Caulfield, Margaret N Kosek
Growth and development shortfalls that are disproportionately prevalent in children living in poor environmental conditions are postulated to result, at least in part, from abnormal gut function. Using data from The Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) longitudinal cohort study, we examine biomarkers of gut inflammation and permeability in relation to environmental exposures and feeding practices. Trends in the concentrations of three biomarkers, myeloperoxidase (MPO), neopterin (NEO), and α-1-antitrypsin (AAT), are described from fecal samples collected during the first 2 years of each child's life...
February 8, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27879516/performance-of-a-commercially-available-mal-antibody-in-the-diagnosis-of-primary-mediastinal-large-b-cell-lymphoma
#19
Michael Gentry, Juraj Bodo, Lisa Durkin, Eric D Hsi
Myelin and lymphocyte (MAL) protein has been previously reported as a highly specific marker for distinguishing primary mediastinal large B-cell lymphoma (PMBL) from diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS). However, there has not been a commercially available MAL antibody for immunohistochemistry. We identified a commercially available MAL monoclonal antibody and evaluated it by immunohistochemistry on 43 cases of PMBL and 63 cases of DLBCL, NOS. We also compared this with a CD200 antibody that was previously reported useful in distinguishing PMBL and DLBCL, NOS...
February 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27821974/effect-of-mental-practice-using-inverse-video-of-the-unaffected-upper-limb-in-a-subject-with-chronic-hemiparesis-after-stroke
#20
Naoki Iso, Shirou Ooso, Noboru Yamamoto, Takefumi Moriuchi, Akira Sagari, Fumiko Iso, Koji Tanaka, Takayuki Tabira, Toshio Higashi
[Purpose] The aim of this case study was to investigate whether a method of mental practice (MP) using an inverse video of a subject's unaffected limb to complement the vividness of motor imagery (MI) would be effective for improving affected upper limb function. [Subjects and Methods] The participant was 60-year-old male in the chronic stage of stroke recovery with left sided hemiparesis. The design of the study was AB method of Single-System-Design. He performed the MP as a home program with DVD. The intervention lasted 30 minutes a session, twice a day, 5 times a week, over 6 weeks...
October 2016: Journal of Physical Therapy Science
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