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Mal practice

Amit Kumar, Sungi Kim, Jwa-Min Nam
The localized surface plasmon resonance of metal nanopar-ticles is the collective oscillation of electrons on particle surface, and is a particle composition, morphology and cou-pling-dependent property. Plasmonic engineering deals with highly precise formation of the targeted nanostructures with targeted plasmonic properties (e.g., electromagnetic field distribution and enhancement) via controlled synthetic, assembling and atomic/molecular tuning strategies. These plasmonically engineered nanostructures (PENs) have a variety of unique and beneficial physical, chemical and bio-logical properties including optical signal enhancement, catalytic property and local temperature-tuning photother-mal property...
October 10, 2016: Journal of the American Chemical Society
Hyun Seung Oh, Eun Joo Kim, Doo Young Kim, Soo Jeong Kim
OBJECTIVE: To investigate the effects of adjuvant mental practice (MP) on affected upper limb function following a stroke using three-dimensional (3D) motion analysis. METHODS: In this AB/BA crossover study, we studied 10 hemiplegic patients who had a stroke within the past 6 months. The patients were randomly allocated to two groups: one group received MP combined with conventional rehabilitation therapy for the first 3 weeks followed by conventional rehabilitation therapy alone for the final 3 weeks; the other group received the same therapy but in reverse order...
June 2016: Annals of Rehabilitation Medicine
Carmen Cantisani, Giovanni Paolino, Giovanni Pellacani, Dario Didona, Marco Scarno, Valentina Faina, Tommaso Gobello, Stefano Calvieri
Non-melanoma skin cancer is the most common skin cancer with an incidence that varies widely worldwide. Among them, actinic keratosis (AK), considered by some authors as in situ squamous cell carcinoma (SCC), are the most common and reflect an abnormal multistep skin cell development due to the chronic ultraviolet (UV) light exposure. No ideal treatment exists, but the potential risk of their development in a more invasive form requires prompt treatment. As patients usually present with multiple AK on fields of actinic damage, there is a need for effective, safe, simple and short treatments which allow the treatment of large areas...
2016: International Journal of Molecular Sciences
Mayra Montalvo, Rushna Ali, Brian Silver, Muhib Khan
Cryptogenic stroke and transient ischemic attack (TIA) account for approximately one-third of stroke patients [1]. Paroxys-mal atrial fibrillation (PAF) has been suggested as a major etiology of these cryptogenic strokes [2, 3]. PAF can be difficult to diagnose because it is intermittent, often brief, and asymptomatic. PAF might be more prevalent than persistent atrial fibrillation in stroke and TIA patients, especially in younger populations [4, 5]. In patients with atrial fibrillation, anticoagulation provides significant risk reduction [6]...
2016: Open Cardiovascular Medicine Journal
Samuel J E Lucas, Jørn W Helge, Uwe H W Schütz, Ralph F Goldman, James D Cotter
This review addresses human capacity for movement in the context of extreme loading and with it the combined effects of metabolic, biomechanical and gravitational stress on the human body. This topic encompasses extreme duration, as occurs in ultra-endurance competitions (e.g. adventure racing and transcontinental races) and expeditions (e.g. polar crossings), to the more gravitationally limited load carriage (e.g. in the military context). Juxtaposed to these circumstances is the extreme metabolic and mechanical unloading associated with space travel, prolonged bedrest and sedentary lifestyle, which may be at least as problematic, and are therefore included as a reference, e...
2016: Extreme Physiology & Medicine
Manoj Kumar, Ashok Kumar Yadav, Vinod Verma, Birbal Singh, Gorakh Mal, Ravinder Nagpal, Rajkumar Hemalatha
Despite the use of microorganisms as therapeutics for over a century, the scientific and clinical admiration of their potential is a recent phenomenon. Genome sequencing and genetic engineering has enabled researchers to develop novel strategies, such as bioengineered probiotics or pharmabiotics, which may become a therapeutic strategy. Bioengineered probiotics with multiple immunogenic or antagonistic properties could be a viable option to improve human health. The bacteria are tailored to deliver drugs, therapeutic proteins or gene therapy vectors with precision and a higher degree of site specificity than conventional drug administration regimes...
2016: Future Microbiology
Vaishnevi N Thirunavukkarasu, Srinivas Sulugodu Ramachandra, Daniel D Dicksit, Kalyan C Gundavarapu
BACKGROUND AND OBJECTIVES: Various extraction protocols have been followed for successful orthodontic treatment. The purpose of this study was to evaluate the extraction protocols in patients who had previously undergone orthodontic treatment and also who had reported for continuing orthodontic treatment from other clinics. MATERIALS AND METHODS: One hundred thirty eight patients who registered for orthodontic treatment at the Faculty of Dentistry were divided into 10 extraction protocols based on the Orthodontic treatment protocol given by Janson et al...
January 2016: Contemporary Clinical Dentistry
Melissa S Y Thong, Adrian A Kaptein, Pauline A J Vissers, Gerard Vreugdenhil, Lonneke V van de Poll-Franse
PURPOSE: Cancer survivors construct perceptions of illness as a (mal)adaptive mechanism. These perceptions motivate/drive subsequent self-management behaviors toward symptoms and treatment that influence health outcomes. Negative illness perceptions have been associated with increased mortality in other chronically ill groups. However, this association is under-researched in cancer survivors. We aimed to explore the association between illness perceptions and mortality in stage I-III progression-free colorectal cancer (CRC) survivors...
October 2016: Journal of Cancer Survivorship: Research and Practice
Esther Blanco, Beatriz Guerra, Beatriz G de la Torre, Sira Defaus, Aldo Dekker, David Andreu, Francisco Sobrino
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals. We have reported (Cubillos et al., 2008) that a synthetic dendrimeric peptide consisting of four copies of a B-cell epitope [VP1(136-154)] linked through thioether bonds to a T-cell epitope [3A(21-35)] of FMDV [B4T(thi)] elicits potent B- and T-cell specific responses and confers solid protection in pigs to type C FMDV challenge. Herein we show that downsized versions of this peptide bearing two copies of a B-cell epitope from a type O isolate and using thioether [B2T(thi)] or maleimide [B2T(mal)] conjugation chemistries for their synthesis elicited in swine similar or higher B and T-cell specific responses than tetravalent B4T(thi)...
May 2016: Antiviral Research
Brian G A Dalton, Katherine W Gonzalez, Michael C Keirsy, Douglas C Rivard, Shawn D St Peter
PURPOSE: Historically, a chest radiograph was obtained after central line placement in the operating room. Recent retrospective studies have questioned the need for this radiograph. The prevailing current practice at our center is to order chest radiograph only for symptomatic patients. This study examines the outcomes of selective chest radiography after fluoroscopic guided central line placement. METHODS: After obtaining institutional review board approval, a single institution retrospective chart review of patients undergoing central venous catheter placement by the pediatric surgery or interventional radiology service between January 2010 and July 2014 was performed...
September 2016: Journal of Pediatric Surgery
Maryam Sadat Fakhri-Bafghi, Seyedeh Farnaz Ghasemi-Niri, Sara Mostafalou, Mona Navaei-Nigjeh, Maryam Baeeri, Azadeh Mohammadirad, Mohammad Abdollahi
OBJECTIVE: Organophosphorus (OP) compounds are used to control pests, however they can reach the food chain and enter the human body causing serious health problems by means of acetylcholinesterase (AChE) inhibition and oxidative stress (OS). Among the OPs, chlorpyrifos (CHP), malathion (MAL), and diazinon (DIA) are commonly used for commercial extermination purposes, in addition to veterinary practices, domestic, agricul- ture and public health applications. Two new recently registered medicines that contain selenium and other antioxidants, IMOD and angipars (ANG), have shown beneficial ef- fects for OS related disorders...
2016: Cell Journal
Gibson Erick Kapanda, Charles Muiruri, Ahaz T Kulanga, Chrispina N Tarimo, Esther Lisasi, Lucy Mimano, Kien Mteta, John A Bartlett
BACKGROUND: Mal-distribution of health care workers is a global health challenge that exacerbates health disparities, especially in resource-limited settings. Interventions to mitigate the problem have targeted qualified personnel with little focus on medical students. However, studies have demonstrated that rural rotations positively influence students to practice in rural settings upon graduation. To evaluate the influence of peripheral rotations in a resource-limited setting, the Kilimanjaro Christian Medical University College introduced a 12-week clerkship rotation in peripheral hospitals for third-year medical (MD3) students in 2012...
2016: BMC Medical Education
Stephen J Page, Peter G Levine, Brittani A Basobas
OBJECTIVE: To determine the impact of repetitive task-specific practice (RTP) integrating electrical stimulation and behavioral supports on upper extremity (UE) impairment, gross manual dexterity, and paretic UE amount and quality of use in chronic stroke survivors exhibiting moderate, stable UE deficits. DESIGN: Case series with 3-month follow-up. SETTING: Outpatient rehabilitation hospital. PARTICIPANTS: Persons (N=9) who experienced a stroke >12 months before enrollment and exhibiting chronic, moderate, stable UE impairment...
May 2016: Archives of Physical Medicine and Rehabilitation
Alessia Cusimano, Ahmed Mohammed Alaaeldien Beniamin Abdelghany, Andrea Donadini
BACKGROUND: There are a lot of different causes of abdominal pain; in this case, a young woman suffers from three diseases with similar symptoms. Adult intestinal mal-rotation is a rare condition of deviation from the normal 270° counter clockwise rotation of the midgut resulting in, not only mal-position of the small intestine, but also mal-fixation of the mesentery. Fitz-Hugh-Curtis syndrome is a rare complication of pelvic inflammatory disease; it involves liver capsule inflammation associated with genital tract infection, which is usually caused by Neisseria gonorrhoea and Chlamydia trachomatis...
2016: BMC Women's Health
Wolfgang G Philipp-Dormston, Sigrid Karrer, Holger Petering, Claas Ulrich, Thomas Dirschka, Carola Berking, Anke S Lonsdorf, Peter Arne Gerber, Sonja Radakovic, Robert E Hunger, Rolf-Markus Szeimies
Photodynamic Therapy (PDT) is one of the standard treatment modalities for actinic keratoses (AKs). Daylight PDT (DL-PDT) with MAL cream is a rather recent development, which, instead of an artificial light source, uses daylight for the activation of the photosensitizer. The present review summarizes available data based on a selective literature search, highlights practical aspects, and reflects the authors' expert knowledge in using DL-PDT. With respect to efficacy, study data shows that DL-PDT is noninferior to conventional PDT (cPDT)...
December 2015: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Kevin Judd McKernan
We sequenced several cannabis genomes in 2011 of June and the first and the longest contigs to emerge were the chloroplast and mitochondrial genomes. Having been a contributor to the Human Genome Project and an eye-witness to the real benefits of immediate data release, I have first hand experience with the potential mal-investment of millions of dollars of tax payer money narrowly averted due to the adopted global rapid data release policy. The policy was vital in reducing duplication of effort and economic waste...
October 21, 2015: Mitochondrial DNA
Roberto Campos Navarro
"Empacho" (abdominal pain and bloating), "mal de ojo" (evil eye), "los aires" (illnesses said to be caught by catching draughts), "el susto" or "espanto" (fright or panic), are the principal and most well-known popular Latin American illnesses. As regards empacho, the medical, historical and ethnographic information is extensive and detailed, since there documents recording it from the 16th century until recent times (2014), and in the case of Chile since 1674. For this review, 109 source documents from libraries in Chile, including some foreign ones, were consulted...
January 2016: Revista Chilena de Pediatría
Anne Barzel, Gesche Ketels, Anne Stark, Britta Tetzlaff, Anne Daubmann, Karl Wegscheider, Hendrik van den Bussche, Martin Scherer
BACKGROUND: Constraint-induced movement therapy (CIMT) is recommended for patients with upper limb dysfunction after stroke, yet evidence to support the implementation of CIMT in ambulatory care is insufficient. We assessed the efficacy of home CIMT, a modified form of CIMT that trains arm use in daily activities within the home environment. METHODS: In this parallel, cluster-randomised controlled trial, we selected 71 therapy practices in northern Germany that treat adult patients with upper limb dysfunction after stroke...
September 2015: Lancet Neurology
Catharina Fluehler, Claudia Colli, Alessandro Gatti, Giusto Trevisan
No abstract text is available yet for this article.
2015: Acta Dermatovenerologica Croatica: ADC
Y Balavarca, K Pearce, J Norden, M Collin, G Jackson, E Holler, R Dressel, H-J Kolb, H Greinix, G Socie, A Toubert, V Rocha, E Gluckman, I Hromadnikova, P Sedlacek, D Wolff, U Holtick, A Dickinson, H Bickeböller
Previous studies of non-histocompatibility leukocyte antigen (HLA) gene single-nucleotide polymorphisms (SNPs) on subgroups of patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT) revealed an association with transplant outcome. This study further evaluated the association of non-HLA polymorphisms with overall survival in a cohort of 762 HSCT patients using data on 26 polymorphisms in 16 non-HLA genes. When viewed in addition to an already established clinical risk score (EBMT-score), three polymorphisms: rs8177374 in the gene for MyD88-adapter-like (MAL; P=0...
November 2015: Bone Marrow Transplantation
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