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https://www.readbyqxmd.com/read/28719336/infant-nutritional-status-feeding-practices-enteropathogen-exposure-socioeconomic-status-and-illness-are-associated-with-gut-barrier-function-as-assessed-by-the-lactulose-mannitol-test-in-the-mal-ed-birth-cohort
#1
Gwenyth O Lee, Benjamin J J McCormick, Jessica C Seidman, Margaret N Kosek, Rashidul Haque, Maribel Paredes Olortegui, Aldo A M Lima, Zulfiqar A Bhutta, Gagandeep Kang, Amidou Samie, Caroline Amour, Carl J Mason, Tahmeed Ahmed, Pablo Peñataro Yori, Domingos B Oliveira, Didar Alam, Sudhir Babji, Pascal Bessong, Estomih Mduma, Sanjaya K Shrestha, Ramya Ambikapathi, Dennis R Lang, Michael Gottlieb, Richard L Guerrant, Laura E Caulfield, For The Mal-Ed Network Investigators
The lactulose mannitol (LM) dual sugar permeability test is the most commonly used test of environmental enteropathy in developing countries. However, there is a large but conflicting literature on its association with enteric infection and host nutritional status. We conducted a longitudinal cohort using a single field protocol and comparable laboratory procedures to examine intestinal permeability in multiple, geographically diverse pediatric populations. Using a previously published systematic review to guide the selection of factors potentially associated with LM test results, we examined the relationships between these factors and mucosal breach, represented by percent lactulose excretion; absorptive area, represented by percent mannitol excretion; and gut barrier function, represented by the L/M ratio...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28611900/replacement-of-dislodged-gastrostomy-tubes-after-stoma-dilation-in-the-pediatric-emergency-department
#2
Shiloni Bhambani, Tammy H Phan, Lance Brown, Andrea W Thorp
INTRODUCTION: A dislodged gastrostomy tube (GT) is a common complaint that requires evaluation in the pediatric emergency department (ED) and, on occasion, will require stoma dilation to successfully replace the GT. The objective of this study was to describe the frequency that stoma dilation is required, the success rate of replacement, complications encountered, and the techniques used to confirm placement of the GT after dilation. METHODS: We conducted a retrospective medical record review of children 0-18 years who presented to the pediatric ED from February 2013 through February 2015 with a dislodged GT that required stoma dilation by pediatric emergency physicians with serially increasing Foley catheter sizes prior to successful placement of the GT...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28573783/towards-a-science-and-practice-of-resilience-in-the-face-of-pain
#3
REVIEW
L Goubert, H Trompetter
The primary objective of this paper is to discuss how a resilience approach to (chronic) pain may advance our current understanding of (mal)adaptation to pain. Different resilience perspectives are described, and future challenges for research, prevention and treatment of (chronic) pain are discussed. Literature searches were performed in Web of Science and PubMed to identify relevant literature on risk and resilience in the context of pain. Resilience can be best defined as the ability to restore and sustain living a fulfilling life in the presence of pain...
June 2, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28460757/our-intellectuals-have-failed-us-system-of-a-down
#4
EDITORIAL
Sundeep Mishra
Medical profession is at cross-roads. On one hand are issues like medical mal-practice and negligence but on the other are loss of respect, low re-imbursement, lawsuits against medical professionals, violence against physicians all contributing to a lot of stress as also a high suicide rate among medical practitioners. While some of the problems seem related to changing societal norms, most of them seem to stem from a failure, active or passive on the part of medical intellectual, moving away from altruism, justice and self regulation to pursuance of self interest with a consequent loss of trust in doctor-patient relationship...
March 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28383850/-the-school-doctorand-suspected-child-abuse-towards-good-practice-recommendations-in-the-child-s-interest
#5
REVIEW
F Noirhomme-Renard, A Blavier, S Lachaussée, C Monville, C Nihoul, C Gosset
Child maltreatment, including all forms of mal¬treatment, remains a major public health problem in high-income countries. Healthcare professionals only contribute to a small proportion of reports. In French-speaking Belgium, almost 100 % of school-aged children are regularly submitted to periodical school health visits. The school health doctor is well placed to recognize neglected or abused children. Based on international good practice recommendations, this paper proposes means for the detection and management of child abuse in the context of school medicine...
October 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28360880/-mal-adaptive-psychological-functioning-of-students-utilizing-university-counseling-services
#6
Valeria Biasi, Rita Cerutti, Luca Mallia, Francesca Menozzi, Nazarena Patrizi, Cristiano Violani
Background: University students confront psychological difficulties that can negatively influence their academic performance. The present study aimed to assess several areas of adaptive and maladaptive psychological functioning among university students who request counseling services. Method: One hundred eighty-four young female students seeking professional psychological help (Counseling seekers) and 185 young female students who have never asked for psychological help (Non-counseling seekers) were asked to complete the Adult Self-Report (ASR) to evaluate both their internalizing and externalizing problems through DSM-oriented scales as well as their adaptive functioning...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28318153/-dental-alveolar-bone-and-dental-arch-remodeling-in-children-orthodontic-diagnosis-and-treatments-based-on-individual-child-arch-development
#7
Li Xiaobing
The etiology of malocclusions basically involves both congenital and environmental factors. Malocclusion is the result of the abnormal development of the orofacial complex (including tooth, dental alveolar bone, upper and lower jaws). Early orthodontic interceptive treatments involve the elimination of all congenital and environmental factors that contribute to the malformation of the orofacial complex, as well as interrupt the deviated development of the orofacial complex and the occlusion. Early orthodontic interceptive treatments mainly aim to use children's growth potential to correct abnormal developments of occlusions and orthodontically treat malocclusions more efficiently...
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28079114/discovering-potential-serological-biomarker-for-chronic-hepatitis-b-virus-related-hepatocellular-carcinoma-in-chinese-population-by-mal-associated-serum-glycoproteomics-analysis
#8
Tianhua Liu, Denghe Liu, Riqiang Liu, Hucong Jiang, Guoquan Yan, Wei Li, Lu Sun, Shu Zhang, Yinkun Liu, Kun Guo
The accuracy of current biomarkers for the diagnosis of hepatocellular carcinoma (HCC), especially chronic Hepatitis B Virus (HBV)-related HCC, is limited. Recent progress in glycoproteomics has provided a novel platform for screening novel serological biomarkers of HCC. In this study, lectin affinity chromatography by Maackia amurensis lectin (MAL) and iTRAQ combined with mass spectrometric analysis were performed to enrich and identify the glycoprotein fractions in serum samples from HBV-related HCC patients and from healthy controls...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28042933/teaching-peritoneal-dialysis-in-australia-an-opportunity-for-improvement
#9
N Boudville, Y Cho, K L Equinox, A E Figueiredo, C M Hawley, K Howard, D W Johnson, M Jose, A Lee, Mal Maley, J Maley, E M Pascoe, G Z Steiner, M Tomlins, D Voss, J Chow
INTRODUCTION: Up to a 10-fold difference in clinical outcomes between Australian peritoneal dialysis (PD) units exists. There is an international focus on the harmonisation of educational practices in PD to determine whether this may lead to improved patient outcomes. AIMS: Evaluate the current teaching practices of nurses and patients in Australian PD units. METHODS: An online survey with questions on nurse and patient training was made available to PD units in Australia...
January 2, 2017: Nephrology
https://www.readbyqxmd.com/read/27994110/dynamics-and-trends-in-fecal-biomarkers-of-gut-function-in-children-from-1-24-months-in-the-mal-ed-study
#10
Benjamin J J McCormick, Gwenyth O Lee, Jessica C Seidman, Rashidul Haque, Dinesh Mondal, Josiane Quetz, Aldo A M Lima, Sudhir Babji, Gagandeep Kang, Sanjaya K Shrestha, Carl J Mason, Shahida Qureshi, Zulfiqar A Bhutta, Maribel Paredes Olortegui, Pablo Peñataro Yori, Amidou Samie, Pascal Bessong, Caroline Amour, Estomih Mduma, Crystal L Patil, Richard L Guerrant, Dennis R Lang, Michael Gottlieb, Laura E Caulfield, Margaret N Kosek
Growth and development shortfalls that are disproportionately prevalent in children living in poor environmental conditions are postulated to result, at least in part, from abnormal gut function. Using data from The Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) longitudinal cohort study, we examine biomarkers of gut inflammation and permeability in relation to environmental exposures and feeding practices. Trends in the concentrations of three biomarkers, myeloperoxidase (MPO), neopterin (NEO), and α-1-antitrypsin (AAT), are described from fecal samples collected during the first 2 years of each child's life...
February 8, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27879516/performance-of-a-commercially-available-mal-antibody-in-the-diagnosis-of-primary-mediastinal-large-b-cell-lymphoma
#11
Michael Gentry, Juraj Bodo, Lisa Durkin, Eric D Hsi
Myelin and lymphocyte (MAL) protein has been previously reported as a highly specific marker for distinguishing primary mediastinal large B-cell lymphoma (PMBL) from diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS). However, there has not been a commercially available MAL antibody for immunohistochemistry. We identified a commercially available MAL monoclonal antibody and evaluated it by immunohistochemistry on 43 cases of PMBL and 63 cases of DLBCL, NOS. We also compared this with a CD200 antibody that was previously reported useful in distinguishing PMBL and DLBCL, NOS...
February 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27821974/effect-of-mental-practice-using-inverse-video-of-the-unaffected-upper-limb-in-a-subject-with-chronic-hemiparesis-after-stroke
#12
Naoki Iso, Shirou Ooso, Noboru Yamamoto, Takefumi Moriuchi, Akira Sagari, Fumiko Iso, Koji Tanaka, Takayuki Tabira, Toshio Higashi
[Purpose] The aim of this case study was to investigate whether a method of mental practice (MP) using an inverse video of a subject's unaffected limb to complement the vividness of motor imagery (MI) would be effective for improving affected upper limb function. [Subjects and Methods] The participant was 60-year-old male in the chronic stage of stroke recovery with left sided hemiparesis. The design of the study was AB method of Single-System-Design. He performed the MP as a home program with DVD. The intervention lasted 30 minutes a session, twice a day, 5 times a week, over 6 weeks...
October 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27793071/self-training-to-improve-ue-function-at-the-chronic-stage-post-stroke-a-pilot-randomized-controlled-trial
#13
Debbie Rand, Harold Weingarden, Ronit Weiss, Anat Yacoby, Shlomit Reif, Rachel Malka, David Andrew Shiller, Gabi Zeilig
BACKGROUND AND PURPOSE: On-going practice and use of the weaker upper extremity (UE) are important for maintaining and improving function in individuals with chronic stroke. The effectiveness of two self-training programs for UE function and daily-use was compared. METHODS: In this pilot, single-blinded clinical trial, individuals with chronic stroke were randomized to video-games or traditional self-training (1-hour/day, 6-times/week, 5 weeks). Assessments were performed pre-intervention (an average of two assessments), post-intervention, and at 4-week follow-up...
October 28, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27788605/a-consensus-on-the-use-of-daylight-photodynamic-therapy-in-the-uk
#14
Sally Ibbotson, Robin Stones, Jonathan Bowling, Sandra Campbell, Stephen Kownacki, Muthu Sivaramakrishnan, Ronan Valentine, Colin A Morton
BACKGROUND: Actinic keratoses (AKs) are a consequence of chronic exposure to ultraviolet radiation. Treatment of chronically photo-damaged skin and AKs is driven by risk of progression to squamous cell carcinoma, as well as for symptomatic relief. Conventional photodynamic therapy (c-PDT) is indicated when AKs are multiple or confluent and if patients respond poorly or are unable to tolerate other therapies. c-PDT is limited by the field size that can be treated in single sessions and can cause significant discomfort...
June 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27723324/plasmonically-engineered-nanoprobes-for-biomedical-applications
#15
Amit Kumar, Sungi Kim, Jwa-Min Nam
The localized surface plasmon resonance of metal nanoparticles is the collective oscillation of electrons on particle surface, induced by incident light, and is a particle composition-, morphology-, and coupling-dependent property. Plasmonic engineering deals with highly precise formation of the targeted nanostructures with targeted plasmonic properties (e.g., electromagnetic field distribution and enhancement) via controlled synthetic, assembling, and atomic/molecular tuning strategies. These plasmonically engineered nanoprobes (PENs) have a variety of unique and beneficial physical, chemical, and biological properties, including optical signal enhancement, catalytic, and local temperature-tuning photothermal properties...
November 9, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27446776/effects-of-adjuvant-mental-practice-on-affected-upper-limb-function-following-a-stroke-results-of-three-dimensional-motion-analysis-fugl-meyer-assessment-of-the-upper-extremity-and-motor-activity-logs
#16
Hyun Seung Oh, Eun Joo Kim, Doo Young Kim, Soo Jeong Kim
OBJECTIVE: To investigate the effects of adjuvant mental practice (MP) on affected upper limb function following a stroke using three-dimensional (3D) motion analysis. METHODS: In this AB/BA crossover study, we studied 10 hemiplegic patients who had a stroke within the past 6 months. The patients were randomly allocated to two groups: one group received MP combined with conventional rehabilitation therapy for the first 3 weeks followed by conventional rehabilitation therapy alone for the final 3 weeks; the other group received the same therapy but in reverse order...
June 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27409613/mal-daylight-photodynamic-therapy-for-actinic-keratosis-clinical-and-imaging-evaluation-by-3d-camera
#17
Carmen Cantisani, Giovanni Paolino, Giovanni Pellacani, Dario Didona, Marco Scarno, Valentina Faina, Tommaso Gobello, Stefano Calvieri
Non-melanoma skin cancer is the most common skin cancer with an incidence that varies widely worldwide. Among them, actinic keratosis (AK), considered by some authors as in situ squamous cell carcinoma (SCC), are the most common and reflect an abnormal multistep skin cell development due to the chronic ultraviolet (UV) light exposure. No ideal treatment exists, but the potential risk of their development in a more invasive form requires prompt treatment. As patients usually present with multiple AK on fields of actinic damage, there is a need for effective, safe, simple and short treatments which allow the treatment of large areas...
July 11, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27347225/long-term-arrhythmia-monitoring-in-cryptogenic-stroke-who-how-and-for-how-long
#18
Mayra Montalvo, Rushna Ali, Brian Silver, Muhib Khan
Cryptogenic stroke and transient ischemic attack (TIA) account for approximately one-third of stroke patients [1]. Paroxys-mal atrial fibrillation (PAF) has been suggested as a major etiology of these cryptogenic strokes [2, 3]. PAF can be difficult to diagnose because it is intermittent, often brief, and asymptomatic. PAF might be more prevalent than persistent atrial fibrillation in stroke and TIA patients, especially in younger populations [4, 5]. In patients with atrial fibrillation, anticoagulation provides significant risk reduction [6]...
2016: Open Cardiovascular Medicine Journal
https://www.readbyqxmd.com/read/27110357/moving-in-extreme-environments-extreme-loading-carriage-versus-distance
#19
REVIEW
Samuel J E Lucas, Jørn W Helge, Uwe H W Schütz, Ralph F Goldman, James D Cotter
This review addresses human capacity for movement in the context of extreme loading and with it the combined effects of metabolic, biomechanical and gravitational stress on the human body. This topic encompasses extreme duration, as occurs in ultra-endurance competitions (e.g. adventure racing and transcontinental races) and expeditions (e.g. polar crossings), to the more gravitationally limited load carriage (e.g. in the military context). Juxtaposed to these circumstances is the extreme metabolic and mechanical unloading associated with space travel, prolonged bedrest and sedentary lifestyle, which may be at least as problematic, and are therefore included as a reference, e...
2016: Extreme Physiology & Medicine
https://www.readbyqxmd.com/read/27070955/bioengineered-probiotics-as-a-new-hope-for-health-and-diseases-an-overview-of-potential-and-prospects
#20
REVIEW
Manoj Kumar, Ashok Kumar Yadav, Vinod Verma, Birbal Singh, Gorakh Mal, Ravinder Nagpal, Rajkumar Hemalatha
Despite the use of microorganisms as therapeutics for over a century, the scientific and clinical admiration of their potential is a recent phenomenon. Genome sequencing and genetic engineering has enabled researchers to develop novel strategies, such as bioengineered probiotics or pharmabiotics, which may become a therapeutic strategy. Bioengineered probiotics with multiple immunogenic or antagonistic properties could be a viable option to improve human health. The bacteria are tailored to deliver drugs, therapeutic proteins or gene therapy vectors with precision and a higher degree of site specificity than conventional drug administration regimes...
2016: Future Microbiology
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