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https://www.readbyqxmd.com/read/29049257/management-of-moisture-associated-skin-damage-a-scoping-review
#1
Kevin Y Woo, Dimitri Beeckman, Debashish Chakravarthy
BACKGROUND: Protecting the skin against moisture-associated damage is an important component of comprehensive skin and wound care. Based on a review of literature, the authors propose key interventions to protect and prevent damage in the skin folds, perineum, and areas surrounding a wound or stoma. OBJECTIVE: The aim of this scoping review is to identify and provide a narrative integration of the existing evidence related to the management and prevention of moisture-associated skin damage (MASD)...
November 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29048948/the-spectrum-of-sickle-hemoglobin-related-nephropathy-from-sickle-cell-disease-to-sickle-trait
#2
Rakhi P Naik, Vimal K Derebail
Renal dysfunction is among the most common complication of sickle cell disease (SCD), from hyposthenuria in children to progression to overt chronic kidney disease (CKD) in young adults. Emerging evidence now suggests that sickle hemoglobin-related nephropathy extends to individuals with sickle cell trait (SCT). Areas covered: This review will highlight the pathophysiology, epidemiology, and management recommendations for sickle nephropathy in both SCD and SCT. In addition, it will focus on the major demographic and genetic modifiers of renal disease in sickling hemoglobinopathies...
October 19, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/29047332/a-set-of-systematic-reviews-to-help-reduce-inappropriate-prescribing-to-older-people-study-protocol
#3
Yolanda V Martinez, Anna Renom-Guiteras, David Reeves, R Erandie Ediriweera de Silva, Aneez Esmail, Ilkka Kunnamo, Anja Rieckert, Christina Sommerauer, Andreas Sönnichsen
BACKGROUND: Multimorbidity and polypharmacy are common in older people. Assessment tools or lists of criteria aimed at supporting prescription decisions for older people exist, but have often been based on expert opinion with insufficient consideration of the evidence available. The present paper describes the methods we are using to systematically review the existing evidence on the efficacy and safety of the most commonly prescribed drugs for older people in the management of their chronic medical conditions and to develop recommendations to reduce inappropriate prescriptions for incorporation into the Comprehensive Medication Review (CMR) tool developed by the PRIMA-eDS European project...
October 16, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29045232/imaging-neoadjuvant-therapy-response-in-breast-cancer
#4
Amy M Fowler, David A Mankoff, Bonnie N Joe
The use of neoadjuvant systemic therapy in the treatment of breast cancer patients is increasing beyond the scope of locally advanced disease. Imaging provides important information in assessing response to therapy as a complement to conventional tumor measurements via physical examination. The purpose of this article is to discuss the advantages and limitations of current assessment methods, as well as review functional and molecular imaging approaches being investigated as emerging techniques for evaluating neoadjuvant therapy response for patients with primary breast cancer...
November 2017: Radiology
https://www.readbyqxmd.com/read/29042760/a-scoping-review-of-crisis-teams-managing-dementia-in-older-people
#5
Amy Streater, Donna Maria Coleston-Shields, Jennifer Yates, Miriam Stanyon, Martin Orrell
BACKGROUND: Research on crisis teams for older adults with dementia is limited. This scoping review aimed to 1) conduct a systematic literature review reporting on the effectiveness of crisis interventions for older people with dementia and 2) conduct a scoping survey with dementia crisis teams mapping services across England to understand operational procedures and identify what is currently occurring in practice. METHODS: For the systematic literature review, included studies were graded using the Critical Appraisal Skills Programme checklist...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29042375/non-invasive-brain-stimulation-interventions-for-management-of-chronic-central-neuropathic-pain-a-scoping-review-protocol
#6
Mei Lin Chen, Lin Yao, Jennifer Boger, Kathryn Mercer, Benjamin Thompson, Ning Jiang
INTRODUCTION: Pain can affect people regardless of age, gender or ethnicity. Chronic central neuropathic pain (CCNP) is a debilitating condition that affects populations such as stroke survivors, amputees, spinal cord injury patients and patients with multiple sclerosis, with prevalence rates between 30% and 80%. This condition can be caused by a lesion or disease affecting the somatosensory system. CCNP is notoriously drug resistant, and few effective CCNP treatment or management strategies exist...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29040028/elaboration-in-type-primary-structure-and-bioactivity-of-polysaccharides-derived-from-mollusks
#7
Ling Chong Wang, Liu Qing Di, Jun Song Li, Li Hong Hu, Jian Ming Cheng, Hao Wu
Over the past decades, numerous Mollusca species have received more attention in development and utilization as valuable bio-resources. Many efforts have been focused on investigating mollusk polysaccharides because of their rich content, ease of extraction, diversified sorts, specific structure, various biofunctions and potent activities. To date, many mollusks, especially species of gastropods, bivalves, or cephalopods, have been reported containing polysaccharide compounds in tissues with abundant amount, and most of polysaccharides are obtainable through combining techniques of extraction, separation and purification...
October 17, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29039980/advances-in-the-chromosome-centric-human-proteome-project-looking-to-the-future
#8
Young-Ki Paik, Gilbert S Omenn, Lydie Lane, Christopher M Overall
The mission of the Chromosome-Centric Human Proteome Project (C-HPP), is to map and annotate the entire predicted human protein set (~20,000 proteins) encoded by each chromosome. The initial steps of the project are focused on "missing proteins (MPs)", which lacked documented evidence for existence at protein level. In addition to remaining 2,579 MPs, we also target those annotated proteins having unknown functions, uPE1 proteins, alternative splice isoforms and post-translational modifications. We also consider how to investigate various protein functions involved in cis-regulatory phenomena, amplicons lncRNAs and smORFs...
October 17, 2017: Expert Review of Proteomics
https://www.readbyqxmd.com/read/29039762/marine-derived-2-aminoimidazolone-alkaloids-leucettamine-b-related-polyandrocarpamines-inhibit-mammalian-and-protozoan-dyrk-clk-kinases
#9
Nadège Loaëc, Eletta Attanasio, Benoît Villiers, Emilie Durieu, Tania Tahtouh, Morgane Cam, Rohan A Davis, Aline Alencar, Mélanie Roué, Marie-Lise Bourguet-Kondracki, Peter Proksch, Emmanuelle Limanton, Solène Guiheneuf, François Carreaux, Jean-Pierre Bazureau, Michelle Klautau, Laurent Meijer
A large diversity of 2-aminoimidazolone alkaloids is produced by various marine invertebrates, especially by the marine Calcareous sponges Leucetta and Clathrina. The phylogeny of these sponges and the wide scope of 2-aminoimidazolone alkaloids they produce are reviewed in this article. The origin (invertebrate cells, associated microorganisms, or filtered plankton), physiological functions, and natural molecular targets of these alkaloids are largely unknown. Following the identification of leucettamine B as an inhibitor of selected protein kinases, we synthesized a family of analogues, collectively named leucettines, as potent inhibitors of DYRKs (dual-specificity, tyrosine phosphorylation regulated kinases) and CLKs (cdc2-like kinases) and potential pharmacological leads for the treatment of several diseases, including Alzheimer's disease and Down syndrome...
October 17, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29039387/personal-health-record-a-scoping-review
#10
Asma Hidki, Matthijs Denbesten
No abstract text is available yet for this article.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29038182/protocol-for-a-scoping-review-to-identify-and-map-the-global-health-personnel-considered-skilled-attendants-at-birth-in-low-and-middle-income-countries-between-2000-and-2015
#11
Amy J Hobbs, Ann-Beth Moller, Liliana Carvajal-Aguirre, Agbessi Amouzou, Doris Chou, Lale Say
INTRODUCTION: Despite progress towards the Millennium Development Goals (MDG), maternal mortality remains high in countries where there are shortages of skilled personnel able to manage and provide quality care during pregnancy and childbirth. The 'percentage of births attended by skilled health personnel' (SAB, skilled attendants at birth) was a key indicator for tracking progress since the MDGs and is part of the Sustainable Development Goal agenda. However, due to contextual differences between and within countries on the definition of SAB, a lack of clarity exists around the training, competencies, and skills they are qualified to perform...
October 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29037963/conversion-between-noise-exposure-indicators-leq24h-lday-levening-lnight-ldn-and-lden-principles-and-practical-guidance
#12
Mark Brink, Beat Schäffer, Reto Pieren, Jean Marc Wunderli
This article presents empirically derived conversion rules between the environmental noise exposure metrics Leq24h, LDay, LEvening, LNight, Ldn, and Lden for the noise sources road, rail and air traffic. It caters to researchers that need to estimate the value of one (unknown) noise metric from the value of another (known) metric, e.g. in the scope of epidemiological meta-analyses or systematic reviews, when results from different studies are pooled and need to be related to one common exposure metric. Conversion terms are derived using two empirical methods a) based on analyzing the diurnal variation of traffic, and b) by analyzing differences between calculated noise exposure metrics...
October 9, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29037573/pharmacists-scope-of-practice-supports-for-canadians-with-diabetes
#13
Kerry Mansell, Kirsten Edmunds, Lisa Guirguis
OBJECTIVES: The pharmacists' role in Canada has significantly advanced over the past decade, resulting in increasing access to primary care services. This study aimed to characterize pharmacists' expanded scope of practice as it relates to providing services to Canadians with diabetes. METHODS: This environmental scan characterized services that could be useful to Canadians with diabetes in each of the provinces (excluding the territories): immunizations, medication prescribing, ordering and interpreting laboratory tests, and medication reviews...
October 13, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29036502/three-cases-of-fatal-acrylfentanyl-toxicity-in-the-united-states-and-a-review-of-literature
#14
Daniel C Butler, Kevin Shanks, George S Behonick, Dustin Smith, Susan E Presnell, Lee Marie Tormos
Fentanyl analogs pose a unique challenge for forensic pathologists and toxicologists. The extreme potency of these analogs results in minute blood, urine and vitreous concentrations that are technically difficult to identify. This in addition to their absence from standard drug screening may potentiate a setting of apparent drug overdose without an immediately identifiable source. The following case series illustrates three such encounters with acrylfentanyl, an analog whose presence has not yet been reported in the scientific literature in the United States...
September 28, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/29035964/medication-safety-programs-in-primary-care-a-scoping-review
#15
Hanan Khalil, Monica Shahid, Libby Roughead
BACKGROUND: Medication safety plays an essential role in all healthcare organizations; improving this area is paramount to quality and safety of any wider healthcare program. While several medication safety programs in the hospital setting have been described and the associated impact on patient safety evaluated, no systematic reviews have described the impact of medication safety programs in the primary care setting. A preliminary search of the literature demonstrated that no systematic reviews, meta-analysis or scoping reviews have reported on medication safety programs in primary care; instead they have focused on specific interventions such as medication reconciliation or computerized physician order entry...
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035960/web-based-therapeutic-interventions-for-assessing-managing-and-treating-health-conditions-in-indigenous-people-a-scoping-review-protocol
#16
Odette Gibson, Rachel Reilly, Stephen Harfield, Catalin Tufanaru, James Ward
The objective of the scoping review is to map the international scientific literature on web-based therapeutic interventions (WBTI) used by Indigenous people for assessing, managing and treating health conditions. The focus of this review is WBTIs for a broad range of health conditions, including but not limited to, communicable and non-communicable diseases, mental health conditions (including the broader concept of social and emotional wellbeing), use of harmful substances and gambling.The questions for the scoping review are...
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035958/forgiveness-facilitation-in-palliative-care-a-scoping-review-protocol
#17
Rita Santos Silva, Sílvia Caldeira, Adriana Neves Coelho, João Luís Alves Apóstolo
The objective of this scoping review is to map the nature and extent of forgiveness facilitation interventions that have been implemented and evaluated in palliative care contexts. More specifically, the review questions are.
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035956/information-overload-in-consumers-of-health-related-information-a-scoping-review-protocol
#18
Kenneth Lee, Erin Roehrer, Elizabeth Cummings
The objective of this scoping review is to examine and map the breadth of evidence on information overload in lay adult and adolescent consumers of health-related information.
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035953/rehabilitation-for-tibial-plateau-fractures-in-adults-a-scoping-review-protocol
#19
Tri M Phan, John Arnold, Lucian B Solomon
Based on the observation that rehabilitation practices for tibial plateau fractures are inconsistent and lack uniformity in the published literature, this scoping review will seek to identify all relevant studies that have reported on rehabilitation for tibial plateau fractures in order to comprehensively map the characteristics of the practices. This scoping review will then be used to identify commonalities across the included studies in order to identify potential focus questions for subsequent systematic reviews...
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035951/anthropometric-prediction-equations-for-estimating-body-mass-composition-a-scoping-review-protocol
#20
Kandiah Umapathysivam, Catalin Tufanaru, Renuka Visvanathan, Solomon Yu
The overall aim of this scoping review is to determine the optimal anthropometric variable parameters used to develop predictive equation(s) to estimate the components of body mass composition.The objectives of the scoping review are:The questions for the scoping review are.
October 2017: JBI Database of Systematic Reviews and Implementation Reports
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