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https://www.readbyqxmd.com/read/28938197/a-collagen-membrane-containing-osteogenic-protein-1-facilitates-bone-regeneration-in-a-rat-mandibular-bone-defect
#1
Manami Ozaki, Tadahiro Takayama, Takanobu Yamamoto, Yasumasa Ozawa, Mayu Nagao, Natsuko Tanabe, Akira Nakajima, Naoto Suzuki, Masao Maeno, Seiichi Yamano, Shuichi Sato
OBJECTIVES: Osteogenic protein-1 (OP-1) has shown osteoinductive activities and is useful for clinical treatments, including bone regeneration. Regenerative procedures using a bioabsorbable collagen membrane (BCM) are well established in periodontal and implant dentistry. We evaluated the subsequent effects of the BCM in combination with OP-1 on bone regeneration in a rat mandibular circular critical-sized bone defect in vivo. DESIGN: We used 8 rats that received surgery in both sides of the mandible, and created the total 16 defects which were divided into 4 groups: Group 1; no treatment, as a control, Group 2; BCM alone, Group 3; BCM containing low dose 0...
September 8, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28932049/evaluation-of-two-flap-designs-on-the-mandibular-second-molar-after-third-molar-extractions
#2
Nabeeh A Alqahtani, S Khaleelahmed, Farheen Desai
BACKGROUND: The extraction of third molars is associated with some clinical outcomes and periodontal problems. It is imperative to note that the type of incision used in the surgery for the removal of the impacted third molar is critical. The design of the flap influences the healing of the surgically created defect and damage to the distal periodontal area of the adjacent second molar. However, till date, there have been conflicting reports on the influence of different flap designs used for the surgical removal of impacted third molars...
May 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28927926/short-dental-implants-a-scoping-review-of-the-literature-for-patients-with-head-and-neck-cancer
#3
REVIEW
Faraj Edher, Caroline T Nguyen
STATEMENT OF PROBLEM: Dental implants can be essential in the rehabilitation of various cancer defects, but their ideal placement can be complicated by the limited dimensions of the available host bone. Surgical interventions developed to increase the amount of bone are not all predictable or successful and can sometimes be contraindicated. Short dental implants have been suggested as an alternative option in sites where longer implants are not possible. Whether they provide a successful treatment option is unclear...
September 16, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28914592/effect-of-topically-applied-hyaluronic-acid-on-pain-and-palatal-epithelial-wound-healing-an-examiner-blind-randomized-controlled-clinical-trial
#4
Selin Yıldırım, Hafize Öztürk Özener, Başak Doğan, Bahar Kuru
BACKGROUND: This study aimed to evaluate the effects of two different concentrations of topical hyaluronic-acid on post-operative patient discomfort and wound healing of palatal donor sites following free gingival graft (FGG) surgery. METHODS: Thirty-six patients requiring FGG were randomly assigned into three groups in an examiner-blind, randomized-controlled clinical trial. After harvesting palatal grafts, 0.2% and 0.8% hyaluronic-acid gels were used in the test-1 and -2 groups, respectively...
September 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28912859/multidisciplinary-therapy-for-the-treatment-of-malocclusion-in-a-patient-with-chronic-periodontitis-with-a-five-year-follow-up-a-case-report
#5
Dongmei Zhang, Li Lin, Xiaoling Tang, Chen Li, Jingbo Liu, Hongyang Wang, Yaping Pan
Multidisciplinary therapy is essential in dental practice to achieve optimized outcomes. The present case report describes the application of periodontal surgery with a five-year follow-up in a patient with malocclusion and chronic periodontitis. In the presence of periodontal inflammation, orthodontic therapy may result in further periodontal breakdown due to plaque accumulation. In order to prevent this progression, scaling and root planning with a periodontal endoscope was applied, and continuous clinical monitoring and risk assessment was performed every 3 months using a Florida Probe...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28905412/long-term-treatment-costs-for-aggressive-periodontitis-in-a-german-population
#6
Falk Schwendicke, Anne Sophie Biffar, Christian Graetz
AIM: This study assessed the long-term annual costs for treating aggressive periodontitis (AgP) patients. METHODS: A cohort of compliant AgP patients was retrospectively evaluated. Costs for active periodontal therapy (APT, including scaling and root planning, open flap debridement, root resections, but not pocket-elimination or regenerative surgery) and supportive periodontal therapy (SPT, including also costs for restorative, endodontic, prosthetic and surgical treatments) were estimated from a mixed payer-perspective in Germany...
September 14, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28898426/differences-between-inflammatory-and-catabolic-mediators-of-peri-implantitis-and-periodontitis-lesions-following-initial-mechanical-therapy-an-exploratory-study
#7
M Ghighi, A Llorens, B Baroukh, C Chaussain, P Bouchard, M Gosset
BACKGROUND AND OBJECTIVE: The aim of this study was to analyze the differences in inflammatory and catabolic mediators expressed in peri-implantitis compared to periodontitis lesions after non-surgical therapy. Peri-implantitis is associated with a faster rate of bone loss when compared with periodontitis, and peri-implant non-surgical therapy is ineffective to cure peri-implantitis. This may be due to persistent inflammation in peri-implantitis tissues after initial mechanical treatment...
September 12, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28893049/comparative-evaluation-of-the-efficacy-of-bioactive-ceramic-composite-granules-alone-and-in-combination-with-platelet-rich-fibrin-in-the-treatment-of-mandibular-class-ii-furcation-defects-a-clinical-and-radiographic-study
#8
Hima S Lohi, Dilip G Nayak, Ashita S Uppoor
INTRODUCTION: Predictable closure of furcation defects with bone grafts, Guided Tissue Regeneration (GTR) and a combination of the two has remained an elusive goal so far. Hence, evaluation of biomimetic agents as candidate technologies for periodontal regeneration merit due consideration. In this study, Choukroun's Platelet Rich Fibrin (PRF), a second generation platelet concentrate, is combined with bone graft to examine if the addition enhances the therapeutic potential of bone graft in the management of Class II furcation defects...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889194/functions-of-periostin-in-dental-tissues-and-its-role-in-periodontal-tissues-regeneration
#9
REVIEW
Juan Du, Minqi Li
The goal of periodontal regenerative therapy is to predictably restore the tooth's supporting periodontal tissues and form a new connective tissue attachment of periodontal ligament (PDL) fibers and new alveolar bone. Periostin is a matricellular protein so named for its expression primarily in the periosteum and PDL of adult mice. Its biological functions have been widely studied in areas such as cardiovascular physiology and oncology. Despite being initially identified in the dental tissues and bone, investigations of Periostin functions in PDL and alveolar-bone-related physiopathology are less abundant...
September 9, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28882408/dental-and-oropharyngeal-lesions-in-rats-with-chronic-acid-reflux-esophagitis
#10
Rintaro Shimazu, Mihoko Yamamoto, Akimichi Minesaki, Yuichiro Kuratomi
OBJECTIVE: In this study, we evaluated pathological changes in the tooth and pharynx of GERD rats to elucidate the association between gastric acid reflux and oral and pharyngeal diseases. METHODS: An experimental rat model of chronic acid reflux esophagitis was surgically created. The oral cavities were observed histologically every 2 weeks until 20 weeks after surgery. RESULTS: At 10 weeks after surgery, molar crown heights in GERD rats were shorter than that in control rats, and inflammatory cell infiltration by gastric acid reflux was found in the periodontal mucosa of GERD rats...
September 4, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28879344/prognosis-after-treatment-with-multiple-dental-implants-under-general-anesthesia-and-sedation-in-a-cerebral-palsy-patient-with-mental-retardation-a-case-report
#11
Young-Joon Hong, Jung-Bae Dan, Myung-Jin Kim, Hyun Jeong Kim, Kwang-Suk Seo
Cerebral palsy is a non-progressive disorder resulting from central nervous system damage caused by multiple factors. Almost all cerebral palsy patients have a movement disorder that makes dental treatment difficult. Oral hygiene management is difficult and the risks for periodontitis, dental caries and loss of multiple teeth are high. Placement of dental implants for multiple missing teeth in cerebral palsy patients needs multiple rounds of general anesthesia, and the prognosis is poor despite the expense...
June 2017: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/28865820/methodological-quality-assessment-of-systematic-reviews-on-autologous-platelet-concentrates-for-the-treatment-of-periodontal-defects
#12
REVIEW
Massimo Del Fabbro, Alessandra Lolato, Saurav Panda, Stefano Corbella, Anurag Satpathy, Abhaya Chandra Das, Manoj Kumar, Silvio Taschieri
OBJECTIVES: Evaluation of the methodological quality of systematic reviews (SRs) on the effectiveness of autologous platelet concentrates as an adjunct to regenerative procedures for the treatment of periodontal defects. MATERIAL AND METHODS: After a literature screening, eligible SRs were qualitatively assessed using 2 validated instruments: A Measurement Tool to Assess systematic Reviews checklist and Overview Quality Assessment Questionnaire. The characteristics and findings of SRs were also reported...
September 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28844190/smoking-may-lead-to-marginal-bone-loss-around-non-submerged-implant-during-bone-healing-by-altering-salivary-microbiome-a-prospective-study
#13
Xiaobo Duan, Tingxi Wu, Xin Xu, Demeng Chen, Anchun Mo, Yiling Lei, Lei Cheng, Yi Man, Xuedong Zhou, Yongyue Wang, Quan Yuan
BACKGROUND: This prospective and controlled study elucidates the impact of smoking on salivary microbiome and its further influence on marginal bone loss around the implant during a 3-month bone healing. METHODS: The saliva samples were collected preoperatively from 20 periodontally healthy patients with single-tooth replacement in posterior mandible jaw: smokers (n=10) and non-smokers (n=10). MiSeq sequencing of 16S rRNA gene amplicons was used to characterize the salivary microbiome...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28839422/clinical-and-radiographic-comparative-evaluation-of-buccal-and-palatal-corticotomy-with-buccal-corticotomy-in-periodontally-accelerated-osteogenic-orthodontics-with-surgical-bur
#14
Pavankumar Addanki, Jagadish Reddy Gooty, Rajababu Palaparthy
BACKGROUND: Periodontally accelerated osteogenic orthodontics is a clinical procedure that combines selective corticotomy, particulate grafting, and application of orthodontics. It reduces treatment time, increases stability of teeth, and prevents relapse of orthodontic tooth moment. The present study was aimed to explore the clinical and radiographic comparison of bone density changes, retraction time differences in buccal and palatal corticotomy with buccal corticotomy which was done by surgical bur...
April 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28834247/regeneration-of-the-cementum-and-periodontal-ligament-using-local-bdnf-delivery-in-class-ii-furcation-defects
#15
Ryo Jimbo, Jessica Singer, Nick Tovar, Charles Marin, Rodrigo Neiva, Estevam A Bonfante, Malvin N Janal, Hugues Contamin, Paulo G Coelho
Periodontal furcation defects are usually addressed by the placement of a physical barrier which may limit the regenerative potential of periodontal wounds. This study morphometrically quantified the regenerative effect of brain-derived neurotrophic factor (BDNF) in furcation defects in a non-human primate model. Grade II furcation defects (with and without induced inflammation prior to surgery) were created on the first and second molars of eight non-human primates. Defects were treated with open flap debridement and subsequently filled with either: Group A; BDNF (500 µg mL(-1) ) in high-molecular weight-hyaluronic acid (HMW-HA), Group B; BDNF (50 µg mL(-1) ) in HMW-HA, Group C; HMW-HA acid only, Group D; unfilled defect, or Group E; BDNF (500 µg mL(-1) ) in saline...
August 21, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28832673/consumption-and-direct-costs-of-dental-care-for-patients-with-head-and-neck-cancer-a-16-year-cohort-study
#16
Duangjai Lexomboon, Pär Karlsson, Jan Adolfsson, Anders Ekbom, Aron Naimi-Akbar, Shahram Bahmanyar, Scott Montgomery, Gunilla Sandborgh-Englund
Patients with head and neck (H&N) cancer are commonly treated with surgery and/or radiotherapy, which can increase the risk of oral infection, dental caries, and periodontal disease. The present study investigated dental care consumption and costs in patient with H&N cancer before and after the cancer diagnosis. Data from Swedish regional and national registers were used to follow up dental care utilization and dental procedure costs. The analysis included 2,754 patients who had been diagnosed with H&N cancer (exposed cohort) in Stockholm County, Sweden, during 2000-2012 and 13,036 matched persons without cancer (unexposed cohort)...
2017: PloS One
https://www.readbyqxmd.com/read/28831458/cemental-tears-a-report-of-four-cases-and-literature-review
#17
Chengjia Xie, Lu Wang, Pishan Yang, Shaohua Ge
PURPOSE: To present four different cases with a diagnosed cemental tear. The differences in aetiology, clinical diagnosis and treatment of cemental tears are described and discussed in order to provide guidance for clinical practice. CASES: Four patients of different ages presented with gingival swelling and other different complaints. Clinically, localised deep periodontal pockets and inflammation were noted on affected aspects in four cases. Radiographic examination revealed a prickly or flakey structure and bone loss on the affected side of the involved tooth...
2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28828758/open-versus-closed-surgical-exposure-of-canine-teeth-that-are-displaced-in-the-roof-of-the-mouth
#18
REVIEW
Nicola Parkin, Philip E Benson, Bikram Thind, Anwar Shah, Ismail Khalil, Saiba Ghafoor
BACKGROUND: Palatally displaced canines or PDCs are upper permanent canines, commonly known as 'eye' teeth, that are displaced in the roof of the mouth. This can leave unsightly gaps, cause damage to the surrounding roots (which can be so severe that neighbouring teeth are lost or have to be removed) and, occasionally, result in the development of cysts. PDCs are a frequent dental anomaly, present in 2% to 3% of young people.Management of this problem is both time consuming and expensive...
August 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28817738/compliance-with-supportive-periodontal-treatment-in-patients-with-dental-implants
#19
Kai-Fang Hu, Ying-Chu Lin, Kun-Yen Ho, Yu-Hsiang Chou
PURPOSE: The need for dental implants is increasing, and supportive periodontal treatment can achieve long-term success and prevent peri-implantitis. Contributing factors to noncompliance with long-term scheduled supportive periodontal treatment remain unclear. To investigate whether demographic and clinical characteristics are associated with noncompliance, the authors analyzed data for patients who had received dental implants. MATERIALS AND METHODS: The authors recruited patients participating in a supportive periodontal treatment program after receiving permanent prostheses on implants placed from 2005 to 2013...
August 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28817132/plasma-of-argon-cleaning-treatment-on-implant-abutments-in-periodontally-healthy-patients-six-years-postloading-results-of-a-randomized-controlled-trial
#20
Luigi Canullo, Marco Tallarico, Miguel Penarrocha, Giuseppe Corrente, Joseph Fiorellini, David Penarrocha
The aim of this randomized, match-paired, triple-blinded, controlled clinical trial was to assess the 6-year radiographic changes around customized platform-switched abutments placed according to the one abutment-one time concept, with and without plasma of argon cleaning treatment. A total of 20 periodontally healthy patients received one maxillary implant between the premolars. Immediately before stage 2 surgery and abutment connection, patients were randomly assigned to the control (cleaning protocol by steam) or test group (plasma of argon treatment)...
September 2017: International Journal of Periodontics & Restorative Dentistry
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