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https://www.readbyqxmd.com/read/27786471/membrane-insertion-of-a-dinuclear-polypyridylruthenium-ii-complex-revealed-by-solid-state-nmr-and-molecular-dynamics-simulation-implications-for-selective-antibacterial-activity
#1
Daniel K Weber, Marc-Antoine Sani, Matthew T Downton, Frances Separovic, F Richard Keene, J Grant Collins
Dinuclear polypyridylruthenium(II) complexes bridged by a flexible methylene linker have received considerable interest as potential antibacterial agents. Their potency and uptake into bacterial cells is directly modulated by the length of the bridging linker, which has implicated membrane interactions as an essential feature of their mechanism of action. In this work, a combination of molecular dynamics (MD) simulations and solid-state NMR was used to present an atomistic model of a polypyridylruthenium(II) complex bound and incorporated into a bacterial membrane model...
October 27, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27747712/prospective-cohort-study-of-dental-implant-success-rate-in-patients-with-aids
#2
Michael Clayton May, Paul Nielsen Andrews, Shadi Daher, Uday Nitin Reebye
BACKGROUND: Oral health care of patients with acquired immune deficiency syndrome (AIDS) due to human immunodeficiency virus (HIV) is a growing area of concern, taking into consideration the increased life expectancy of patients resulting from antiretroviral therapy. There is insufficient literature regarding the impact of dental implants in AIDS patients. This study investigated the long-term clinical outcome of implant placement in patients diagnosed with AIDS. METHODS: This monocentric study included AIDS patients with CD4 <200 cells/μL, age 18 years or older, and a minimum of one edentulous space requiring implant...
December 2016: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/27607288/design-and-simulation-of-a-biconic-multipass-absorption-cell-for-the-frequency-stabilization-of-the-reference-seeder-laser-in-ipda-lidar
#3
Yongji Mu, Juan Du, Zhongguo Yang, Yanguang Sun, Jiqiao Liu, Xia Hou, Weibiao Chen
The design process and simulation method of a multipass absorption cell used for the frequency stabilization of the reference seeder laser in integrated path differential absorption (IPDA) lidar are presented. On the basis of the fundamental theory of the Herriott multipass cell comprising two spherical mirrors, the initial parameters of the multipass cell, which has an optical path greater than 10 m and consists of two biconic mirrors, were calculated. More than 30 light spots were distributed on each mirror, and the distance between adjacent spots was mostly optimized to greater than six times the beam waist...
September 1, 2016: Applied Optics
https://www.readbyqxmd.com/read/27519819/overproduction-of-individual-gas-vesicle-proteins-perturbs-flotation-antibiotic-production-and-cell-division-in-the-enterobacterium-serratia-sp-atcc-39006
#4
Rita E Monson, Yosuke Tashiro, George P C Salmond
Gas vesicles are intracellular proteinaceous organelles that facilitate bacterial colonization of static water columns. In the enterobacterium Serratia sp. ATCC 39006, gas vesicle formation requires the proteins GvpA1, GvpF1, GvpG, GvpA2, GvpK, GvpA3, GvpF2 and GvpF3 and the three gas vesicle regulatory proteins GvrA, GvrB and GvrC. Deletion of gvpC alters gas vesicle robustness and deletion of gvpN or gvpV results in small bicone vesicles. In this work, we assessed the impacts on gas vesicle formation when each of these 14 essential proteins was overexpressed...
September 2016: Microbiology
https://www.readbyqxmd.com/read/27412731/a-miniaturized-electrochemical-device-integrating-a-biconical-microchannel-and-carbon-fiber-disk-ultramicroelectrode
#5
Fengxia Chang, Xia Xie, Meixian Li, Zhiwei Zhu
A simple, cheap and practicable miniaturized electrochemical device based on a biconical microchannel was developed, for which only 1 μL sample solution was needed to implement a typical electrochemical experiment. The practicability of the designed device was validated by detecting uric acid as a model molecule in human serum.
August 2, 2016: Analyst
https://www.readbyqxmd.com/read/27380654/comparative-performance-of-traps-in-catching-tsetse-flies-diptera-glossinidae-in-tanzania
#6
Imna I Malele, Johnson O Ouma, Hamisi S Nyingilili, Winston A Kitwika, Deusdedit J Malulu, Henry B Magwisha, Eliningeya J Kweka
This study was conducted to determine the efficiency of different tsetse traps in 28 sites across Tanzania. The traps used were biconical, H, NGU, NZI, pyramidal, S3, mobile, and sticky panels. Stationary traps were deployed at a distance of 200 m apart and examined 72 h after deployment. The results showed that 117 (52.2%) out of the 224 traps deployed captured at least one Glossina species. A total of five Glossina species were captured, namely Glossina brevipalpis, Glossina pallidipes, Glossina swynnertoni, Glossina morsitans, and Glossina fuscipes martinii...
2016: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/27247477/evidence-based-evaluation-of-inferior-vena-cava-filter-complications-based-on-filter-type
#7
REVIEW
Steven E Deso, Ibrahim A Idakoji, William T Kuo
Many inferior vena cava (IVC) filter types, along with their specific risks and complications, are not recognized. The purpose of this study was to evaluate the various FDA-approved IVC filter types to determine device-specific risks, as a way to help identify patients who may benefit from ongoing follow-up versus prompt filter retrieval. An evidence-based electronic search (FDA Premarket Notification, MEDLINE, FDA MAUDE) was performed to identify all IVC filter types and device-specific complications from 1980 to 2014...
June 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27241335/thirteen-year-follow-up-of-a-cementless-femoral-stem-and-a-threaded-acetabular-cup-in-patients-younger-than-fifty%C3%A2-years-of-age
#8
Jan Schmolders, Grigoris Amvrazis, Peter H Pennekamp, Andreas Christian Strauss, Max Julian Friedrich, Matthias D Wimmer, Yorck Rommelspacher, Dieter Christian Wirtz, Thomas Wallny
PURPOSE: Compared to older patients undergoing total hip arthroplasty (THA) younger patients are considered to be more active, thereby exposing the implant to significantly higher loads over a much longer period of time. Additionally, cases of secondary osteoarthritis caused by hip dysplasia, femoral head necrosis or rheumatic diseases are much more frequent than among the average patient population. Therefore, durable implant fixation and low wear rates are extremely important to achieve good long-term implant survival in this group of patients...
May 30, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27239380/outcome-of-the-cementless-zweym%C3%A3-ller-bicon-plus-cup-and-sl-plus-stem-in-the-very-elderly-individuals
#9
Egbert J D Veen, Joost C M Schrier, Esther Van't Riet, Mark J Breslau, Alexander F W Barnaart
INTRODUCTION: There is current debate about which type of total hip prosthesis implants are best for the elderly patient. Implanting uncemented total hip arthroplasty (THA) in elderly people remains contested. The aim of present study was to evaluate the outcome of the uncemented Zweymüller BICON-PLUS THA in those with a minimum of 80 years of age. MATERIALS AND METHODS: A retrospective data collection was performed in a regional teaching hospital in the Netherlands...
June 2016: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/27229162/good-mid-to-long-term-tha-outcomes-with-a-modified-cementless-rectangular-biconical-stem-design
#10
Stefano Iori, Roberto Viganò
PURPOSE: Second- and third-generation cementless Zweymüller stems have achieved good long-term outcomes in total hip arthroplasty (THA). The PPF cementless proximal press-fit femoral stem (Biomet Inc.) is based on the Zweymüller stem, with some prominent design differences. This study was designed to assess its performance in terms of survivorship, clinical function, and radiographic outcomes. METHODS: We retrospectively analysed 250 patients (303 hips) who underwent THA between 1998 and 2011...
July 25, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27061509/design-of-psira-with-focusing-lens-concentrating-picosecond-impulse-on-biological-target
#11
A Petrishia, M Sasikala
The Prolate Spheroidal Impulse Radiating Antenna (PSIRA) is used to radiate very fast pulses in a narrow beam with low dispersion and high field amplitude. The PSIRA is suitable to apply fast, intense pulses without direct contact, for skin cancer treatment. In this proposed work, SWB (Slanted Wire Biconical), EPH (Elliptical Profile Horn), TSVS (Tapered Slot Vivaldi Shape) and Tapered Arm Conical Plate (TACP) feed antenna configurations for Prolate Spheroidal Reflector (PSR) are explored to enhance spatial resolution on biological targets...
March 4, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/26981275/feeding-patterns-and-xenomonitoring-of-trypanosomes-among-tsetse-flies-around-the-gashaka-gumti-national-park-in-nigeria
#12
Solomon Ngutor Karshima, Idris A Lawal, Oluseyi Oluyinka Okubanjo
In order to understand the epidemiology of trypanosomoses in Gashaka-Gumti National Park, Nigeria, we determined the density, infection rates, and feeding patterns of tsetse flies using biconical traps, ITS, and mitochondrial cytochrome b PCRs. A total of 631 tsetse flies were captured, of which 531 (84.2%) and 100 (15.8%) were analyzed for trypanosomes and blood meals, respectively. Tsetse distribution varied significantly (p < 0.05) across study sites with average trap and daily catches of 4.39 and 26...
2016: Journal of Parasitology Research
https://www.readbyqxmd.com/read/26875082/-ecology-of-glossina-palpalis-vanderplank-1949-diptera-glossinidae-in-mangrove-area-of-guinea-influence-of-tides-on-tsetse-densities
#13
S M Kagbadouno, E Salou, J B Rayaisse, F Courtin, A Sanon, P Solano, M Camara
The mangrove area on the Guinea littoral constitutes a favourable habitat for transmission of Trypanosoma brucei gambiens, the parasite causing sleeping sickness also called Human African Trypanosmosis (HAT), due the simultaneous presence of the vector (tsetse flies) and the human hosts. In order to assess the influence of the sea tides on the densities of Glossina palpalis gambiensis (Gpg), major vector of HAT in the mangrove, entomological surveys were performed using two transects, according to tides coefficient (great and small) and tide daily fluctuations (high and low)...
May 2016: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/26743231/molecular-genetic-and-physical-analysis-of-gas-vesicles-in-buoyant-enterobacteria
#14
Yosuke Tashiro, Rita E Monson, Joshua P Ramsay, George P C Salmond
Different modes of bacterial taxis play important roles in environmental adaptation, survival, colonization and dissemination of disease. One mode of taxis is flotation due to the production of gas vesicles. Gas vesicles are proteinaceous intracellular organelles, permeable only to gas, that enable flotation in aquatic niches. Gene clusters for gas vesicle biosynthesis are partially conserved in various archaea, cyanobacteria, and some proteobacteria, such as the enterobacterium, Serratia sp. ATCC 39006 (S39006)...
April 2016: Environmental Microbiology
https://www.readbyqxmd.com/read/26698452/rapid-3d-%C3%A2%C2%B5-printing-of-polymer-optical-whispering-gallery-mode-resonators
#15
Jushuai Wu, Xin Guo, A Ping Zhang, Hwa-Yaw Tam
A novel microfabrication method for rapid printing of polymer optical whispering-gallery mode (WGM) resonators is presented. A 3D micro-printing technology based on high-speed optical spatial modulator (SLM) and high-power UV light source is developed to fabricate suspended-disk WGM resonator array using SU-8 photoresist. The optical spectral responses of the fabricated polymer WGM resonators were measured with a biconically tapered optical fiber. Experimental results reveal that the demonstrated method is very flexible and time-saving for rapid fabrication of complex polymer WGM resonators...
November 16, 2015: Optics Express
https://www.readbyqxmd.com/read/26339989/a-bidirection-adjustable-ionic-current-rectification-system-based-on-a-biconical-micro-channel
#16
Fengxia Chang, Cheng Chen, Xia Xie, Lisha Chen, Meixian Li, Zhiwei Zhu
We developed a simple, cheap and bidirectional ionic current rectification system based on the integration of a biconical micro-channel, working electrode and reference electrode. This system may have potential and realistic future value for studying two-way ionic transport in the cell membrane.
October 25, 2015: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/26125383/mode-multiplexer-based-on-integrated-horizontal-and-vertical-polymer-waveguide-couplers
#17
Jiangli Dong, Kin Seng Chiang, Wei Jin
We demonstrate a mode demultiplexer with two cascaded few-mode polymer waveguide directional couplers fabricated on the same substrate along the horizontal and vertical directions, respectively. The three waveguides that form the two couplers have the same core size. The horizontal and vertical couplers are designed to provide complete power transfer for the LP(11a) and LP(11b) modes, with the LP(01) mode staying in the central core that incorporates a biconical taper to suppress any remaining LP(11) modes...
July 1, 2015: Optics Letters
https://www.readbyqxmd.com/read/26074312/probability-of-survival-of-implant-supported-metal-ceramic-and-cad-cam-resin-nanoceramic-crowns
#18
Estevam A Bonfante, Marcelo Suzuki, Fábio C Lorenzoni, Lídia A Sena, Ronaldo Hirata, Gerson Bonfante, Paulo G Coelho
OBJECTIVES: To evaluate the probability of survival and failure modes of implant-supported resin nanoceramic relative to metal-ceramic crowns. METHODS: Resin nanoceramic molar crowns (LU) (Lava Ultimate, 3M ESPE, USA) were milled and metal-ceramic (MC) (Co-Cr alloy, Wirobond C+, Bego, USA) with identical anatomy were fabricated (n=21). The metal coping and a burnout-resin veneer were created by CAD/CAM, using an abutment (Stealth-abutment, Bicon LLC, USA) and a milled crown from the LU group as models for porcelain hot-pressing (GC-Initial IQ-Press, GC, USA)...
August 2015: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/26040845/tsetse-diversity-and-abundance-in-southern-burkina-faso-in-relation-with-the-vegetation
#19
J-B Rayaisse, E Salou, S Kiema, M Akoudjin, D Kaba, M Kagbadouno, V Djohan, M Camara, G-K Dayo, F Courtin, P Solano, J Bouyer
The increase of human population, combined with climatic changes, contributed to the modification of spatial distribution of tsetse flies, main vector of trypanosomiasis. In order to establish and compare tsetse presence and their relationship with vegetation, entomological survey was performed using biconical traps deployed in transects, simultaneously with phyto-sociological study, on the Comoe river at its source in the village of Moussodougou, and in the semi-protected area of Folonzo, both localities in Southern Burkina Faso...
September 2015: Parasitology Research
https://www.readbyqxmd.com/read/26035296/detection-and-identification-of-pathogenic-trypanosome-species-in-tsetse-flies-along-the-como%C3%A3-river-in-c%C3%A3-te-d-ivoire
#20
COMPARATIVE STUDY
Vincent Djohan, Dramane Kaba, Jean-Baptiste Rayaissé, Guiguigbaza-Kossigan Dayo, Bamoro Coulibaly, Ernest Salou, Fabien Dofini, Alain De Marie Koffi Kouadio, Hervé Menan, Philippe Solano
In order to identify pathogenic trypanosomes responsible for African trypanosomiasis, and to better understand tsetse-trypanosome relationships, surveys were undertaken in three sites located in different eco-climatic areas in Côte d'Ivoire during the dry and rainy seasons. Tsetse flies were caught during five consecutive days using biconical traps, dissected and microscopically examined looking for trypanosome infection. Samples from infected flies were tested by PCR using specific primers for Trypanosoma brucei s...
2015: Parasite: Journal de la Société Française de Parasitologie
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