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Parotid Gland Tumor

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https://www.readbyqxmd.com/read/28207533/lymphoepithelial-carcinoma-of-the-salivary-glands
#1
Yeun J Kim, Hyun S Hong, Sun H Jeong, Eun H Lee, Min J Jung
RATIONALE: Lymphoepithelial carcinoma (LEC) is a rare malignancy with the histopathological feature of undifferentiated carcinoma and an intermixed reactive lymphoplasmacytic infiltration. Although clinically significant because of its malignant nature, it is difficult to make a differential diagnosis by preoperative imaging. Here, we report 3 cases of primary LEC arising in the major salivary glands, which showed unusual imaging features unlike other malignant tumors. PATIENT CONCERNS: Our first case is a 44-year-old man with LEC in the right parotid gland, the second case is a 71-year-old woman with LEC in the right submandibular gland, and the third case is a 35-year-old woman with LEC in the right parotid gland...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28180194/prospective-evaluation-of-quasistatic-ultrasound-elastography-use-compared-with-baseline-us-for-parotid-gland-lesions-preliminary-results-of-elasticity-contrast-index-eci-evaluation
#2
Vito Cantisani, Emanuele David, Armando De Virgilio, Paul S Sidhu, Hektor Grazhdani, Antonio Greco, Marco De Vincentiis, Alessandro Corsi, Flaminia De Cristofaro, Luca Brunese, Fabrizio Calliada, Alfredo Blandino, Mario Tombolini, Giorgio Ascenti, Roberto Stramare, Marcello Caratozzolo, Ferdinando D'Ambrosio
AIMS: To assess the diagnostic value of elasticity contrast index (ECI) elastography, in comparison with conventional ultrasound for the differentiation of benign and malignant parotid lesions. MATERIAL AND METHODS: Sixty-three consecutive patients with parotid gland tumors, treated surgically at a single tertiary center were enrolled. Ultrasound evaluation consisted of B-mode, color-Doppler and quasistatic ultrasound elastography (USE), conducted with the ECI technique...
January 31, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28160579/retrospective-study-of-149-cases-of-salivary-gland-carcinoma-in-a-spanish-hospital-population
#3
L Collazo-Fernández, J Campo-Trapero, J Cano-Sánchez, R García-Martín, C Ballestín-Carcavilla
BACKGROUND: The clinical and histological characteristics of salivary gland tumors vary widely, complicating their diagnosis and management, and major differences have been recorded in the distribution of histopathological diagnoses among different countries. MATERIAL AND METHODS: This retrospective study reviewed the demographic (age, sex) and clinicopathological (pathology diagnosis and localization) characteristics of cases diagnosed with primary SGC between June 1992 and May 2014 in the Pathology Department of the 12 de Octubre Hospital of Madrid...
February 4, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28145103/extracapsular-dissection-as-sole-therapy-for-small-low-grade-malignant-tumors-of-the-parotid-gland
#4
Konstantinos Mantsopoulos, Michael Koch, Heinrich Iro
OBJECTIVE: The aim of the study was to investigate whether extracapsular dissection of a primarily unsuspected lesion in the parotid gland could be oncologically sufficient for carefully selected cases of parotid gland malignomas. STUDY DESIGN: Retrospective clinical study. METHODS: The records of all patients treated for primary malignant tumors of the parotid gland solely by means of extracapsular dissection between 2006 and 2013 were studied retrospectively...
January 31, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28141643/primary-carcinosarcoma-of-the-parotid-gland-mimicking-as-parotid-abscess-with-deep-neck-infection
#5
Huu Ngoc Minh Phan, Yong Tae Hong, Ki Hwan Hong
Carcinosarcoma, true malignant mixed tumor, of the parotid is an extremely rare tumor. Pathologically, it is composed of malignant epithelial and malignant mesenchymal elements. The carcinosarcoma of the salivary glands comprised only 0.04% to 0.16% of all malignant salivary tumors with 65% occurring in the parotid gland. This tumor has an aggressive characteristic and is often regarded as a high-grade tumor with distant metastasis occurring in 54% of the patients. Patients usually present between 60 and 65 years of age and most series report no sex predominance...
January 30, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28139343/lymphoepithelial-carcinoma-in-parotid-gland-related-to-ebv-infection-a-case-report
#6
Hiroyuki Maeda, Takuya Yamashiro, Yukashi Yamashita, Hitoshi Hirakawa, Shinya Agena, Takayuki Uehara, Sen Matayoshi, Mikio Suzuki
Lymphoepithelial carcinoma commonly occurs at the nasopharynx and rarely occurs at other sites in the head and neck region. It is well known to occur at limited patients of local area as Asia or Arctic Circle. Related to this point, it is pointed out that this tumor has strong relation with Epstein-Barr Virus (EBV) infection. In this time, we experienced to treat lymphoepithelial carcinoma with metastatic cervical lymph nodes occurring at parotid gland. The morbidity ratio of this tumor is less than one percent of all parotid gland tumors...
January 27, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28133208/-a-case-of-primary-acinic-cell-carcinoma-acc-of-the-breast
#7
Hiroshi Kawai, Ryoma Sugimoto, Norichika Iga, Hirokuni Ikeda, Ryosuke Yoshida, Naohisa Waki, Masahiro Ishizaki, Hideyuki Nishi, Kazuki Yamashita
A49 -year-old woman presented with a 3.5 cm mass in her right breast. Mammography revealed a lobular mass with poorly defined margins and no microcalcification. Ultrasonography showed a hypoechoic mass with an irregular margin. The tumor was diagnosed as breast carcinoma using a core needle biopsy. The patient underwent a modified radical mastectomy with sentinel lymph node biopsy, and received adjuvant chemotherapy. The tumor consisted of 2 types of carcinoma. The center of the tumor was solid-tubular carcinoma, and the periphery was acinic cell carcinoma(ACC)...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28119092/a-new-electroneurography-as-a-prognostic-tool-for-marginal-mandibular-nerve-paralysis-after-parotid-gland-surgery-a-preliminary-evaluation
#8
Shin-Ichi Haginomori, Shin-Ichi Wada, Takahiro Ichihara, Tetsuya Terada, Ryo Kawata
OBJECTIVE: Marginal mandibular nerve paralysis is the most frequent complication of benign parotid tumor surgery and results in cosmetic deformity. The purpose of this study was to develop a new electroneurography method for marginal mandibular nerve paralysis using electroneurography (ENoG) and judge its usefulness for clinical practice. METHODS: Twenty-seven patients who underwent surgery for benign parotid tumor were enrolled. We proposed and use the mandibular angle method, in which the recording electrode was placed on the skin above the depressor anguli oris muscle while the reference electrode was placed on the skin of the parietal region, and percutaneous electrical stimulation was applied to enclose the mandibular angle that could measure the function of the marginal mandibular nerve solely...
January 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28108853/brain-metastasis-of-carcinoma-ex-pleomorphic-adenoma-of-the-parotid-gland-case-report-and-review-of-the-literature
#9
Ruth Lau, Alejandro Fernández-Coello, Noemí Vidal-Sarró, Dennis Céspedes, Angels Camins, Miren Taberna, Andreu Gabarrós
We present an extremely infrequent case of brain metastasis of a parotid tumor. To our knowledge, this is the second case reported of a brain metastasis of a malignant parotid tumor, carcinoma ex pleomorphic adenoma. Pleomorphic adenoma represents 60% of tumors of the parotid gland, and although it is a benign tumor, it can transform into carcinoma ex pleomorphic adenoma in 5% of cases, one of the most aggressive neoplasms of the salivary glands. We want to note the need for an accurate diagnostic. Thanks to aggressive surgical management, our patient survived more than 1½ years...
March 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28095049/rai-avid-warthin-s-tumor-of-the-parotid-gland
#10
Daniel C Rafii, Eric F Greif, Howard Finestone, Jocelyne Karam
No abstract text is available yet for this article.
January 17, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28076460/the-accuracy-of-fine-needle-aspiration-cytology-for-diagnosis-of-parotid-gland-masses-a-clinicopathological-study-of-114-patients
#11
Jens Kristjan Gudmundsson, Aida Ajan, Jahan Abtahi
Objective: Fine-needle aspiration cytology is a valuable method for preoperative assessment of head and neck tumors. However, its accuracy in detection of salivary gland masses is controversial compared with other methods. The aim of this work was to evaluate the effectiveness and accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of parotid gland masses. Material and Methods: Over a 10-year period, 126 parotid gland masses were resected. Retrospective chart reviews of 114 patients were performed...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28074380/usefulness-of-diffusion-weighted-mr-imaging-for-differentiating-between-warthin-s-tumor-and-oncocytoma-of-the-parotid-gland
#12
Hiroki Kato, Keita Fujimoto, Masayuki Matsuo, Keisuke Mizuta, Mitsuhiro Aoki
PURPOSE: To assess the efficacy of diffusion-weighted (DW) MR imaging for differentiating between Warthin's tumor and oncocytoma of the parotid gland. METHODS: Forty-five histopathologically confirmed parotid gland tumors (41 Warthin's tumors and 4 oncocytomas) were examined by MR imaging including DW imaging. (18)F-fluorodeoxyglucose PET/CT was also performed in 9 Warthin's tumors and 3 oncocytomas. We retrospectively reviewed the images and compared the MR signal intensities, apparent diffusion coefficients (ADCs), and maximum standardized uptake values (SUVmax) of the solid components between the two pathologies...
January 10, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28071626/prognostic-factors-in-postoperative-radiotherapy-in-salivary-gland-carcinoma-a-single-institution-experience-from-turkey
#13
M Kandaz, G Soydemir, Z Bahat, E Canyılmaz, A Yöney
BACKGROUND: We reviewed clinical characteristics, treatment outcomes, local and distant failure and prognostic factors in patients with salivary gland carcinoma treated with surgery and postoperative radiotherapy. MATERIALS AND METHODS: We retrospectively reviewed 75 patients with salivary gland cancer. 69 (%92) patients had cancer of the parotid gland, 3 (%4) patients had cancer of the submandibular gland and 3 (%4) patients had cancer of the minor salivary gland...
April 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28055973/outcome-and-long-term-efficacy-of-four-facio-cervical-fields-conformal-radiotherapy-for-nasopharyngeal-carcinoma
#14
Wang Fangzheng, Jiang Chuner, Wang Lei, Chen Weijun, Xu Min, Sun Quanquan, Liu Tongxin, Rihito Aizawa, Masoto Sakamoto, Fu Zhenfu
PURPOSE: To evaluate the outcomes of 255 patients with nasopharyngeal carcinoma (NPC) treated with four facio-cervical fields conformal radiotherapy (4F-CRT). RESULTS: In one patient's 3 different RT treatment modalities, the 4F-CRT techniques resulted in sharper of the dose-volume histograms (DVHs) for primary gross tumor volume (PGTVnx) and planning target volume (PTVnx), similar to the intensity modulated radiation therapy (IMRT). The median follow-up duration was 43 months...
December 31, 2016: Oncotarget
https://www.readbyqxmd.com/read/28050002/pulmonary-tumor-thrombotic-microangiopathy-caused-by-a-parotid-tumor-early-antemortem-diagnosis-and-long-term-survival
#15
Haruka Toyonaga, Michiko Tsuchiya, Chikara Sakaguchi, Hitomi Ajimizu, Yosuke Nakanishi, Seiya Nishiyama, Noboru Morikawa, Yasuyuki Hayashi, Yukio Nagasaka, Hiroshi Yasui
Pulmonary tumor thrombotic microangiopathy (PTTM) is a high-mortality disease that is difficult to diagnose clinically. Our patient was an 80-year-old woman who came to us due to symptoms of increasing dyspnea. A clinical evaluation showed that she had hypoxemia and pulmonary arterial hypertension without any abnormalities in the major pulmonary arteries, bronchi, or alveoli. A lung perfusion scan showed multiple wedge-shaped perfusion defects. Further examination revealed adenocarcinoma in her right parotid gland with metastasis to the submandibular lymph nodes...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28048629/tu-h-campus-jep2-04-deriving-delivered-doses-to-assess-the-viability-of-2-5-mm-margins-in-head-and-neck-sbrt
#16
S Lin, Q Shang, S Pirozzi, A Godley
PURPOSE: To calculate the delivered dose for head and neck SBRT patients using pre-treatment images. This delivered dose was then used to determine the viability of 2.5 mm margins. METHODS: Daily cone beam CTs (CBCTs) were collected for 20 patients along with a planning CT, planned dose, and planning structures. The day 1 CBCT was aligned to the planning CT using the treatment shifts (six degrees of freedom) and then the dose and contours were transferred to the CBCT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048228/su-f-p-26-study-of-radiation-dose-evaluation-for-organs-at-risk-using-mri-in-intensity-modulated-radiation-therapy-for-nasopharyngeal-carcinoma
#17
G Gong, Y Guo, Y Yin
PURPOSE: To study the contour and dosimetric feature of organs at risk (OARs) applying magnetic resonance imaging (MRI) images in intensity modulated radiation therapy (IMRT) of nasopharyngeal carcinoma (NPC) compared to computed tomography (CT) images. METHODS: 35 NPC patients was selected into this trail. CT simulation with non-contrast and contrast enhanced scan, MRI simulation with non-contrast and contrast enhanced T1, T2 and diffusion weighted imaging were achieved sequentially...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047821/su-f-t-523-radiobiological-comparison-of-helical-tomotherapy-and-vmat-in-the-treatment-of-head-and-neck-tumors
#18
R Woods, P Mavroidis, M Lehman-Davis, M Kostich, T Cook, B Chera, S Das, J Lian
PURPOSE: This study aims at comparing the efficacy of Helical Tomotherapy (TOMO) and Volumetric Modulated Arc Therapy (VMAT) in producing highly conformal dose distributions in challenging head & neck cancer patients. Furthermore, to interpret the dosimetric findings into expected tissue response rates in order to estimate their clinical impact. METHODS: Seven patients were studied and for each patient two treatment plans (one TOMO and one VMAT) were created. Structures used for optimization were: high risk PTV, standard risk PTV, brainstem, spinal cord, parotid gland, larynx, mandible and surrounding tissue...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047089/th-cd-206-05-machine-learning-based-segmentation-of-organs-at-risks-for-head-and-neck-radiotherapy-planning
#19
B Ibragimov, F Pernus, P Strojan, L Xing
PURPOSE: Accurate and efficient delineation of tumor target and organs-at-risks is essential for the success of radiotherapy. In reality, despite of decades of intense research efforts, auto-segmentation has not yet become clinical practice. In this study, we present, for the first time, a deep learning-based classification algorithm for autonomous segmentation in head and neck (HaN) treatment planning. METHODS: Fifteen HN datasets of CT, MR and PET images with manual annotation of organs-at-risk (OARs) including spinal cord, brainstem, optic nerves, chiasm, eyes, mandible, tongue, parotid glands were collected and saved in a library of plans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047063/tu-h-campus-jep3-02-automated-dose-accumulation-and-dose-accuracy-assessment-for-online-or-offline-adaptive-replanning
#20
G Chen, E Ahunbay, X Li
PURPOSE: With introduction of high-quality treatment imaging during radiation therapy (RT) delivery, e.g., MR-Linac, adaptive replanning of either online or offline becomes appealing. Dose accumulation of delivered fractions, a prerequisite for the adaptive replanning, can be cumbersome and inaccurate. The purpose of this work is to develop an automated process to accumulate daily doses and to assess the dose accumulation accuracy voxel-by-voxel for adaptive replanning. METHODS: The process includes the following main steps: 1) reconstructing daily dose for each delivered fraction with a treatment planning system (Monaco, Elekta) based on the daily images using machine delivery log file and considering patient repositioning if applicable, 2) overlaying the daily dose to the planning image based on deformable image registering (DIR) (ADMIRE, Elekta), 3) assessing voxel dose deformation accuracy based on deformation field using predetermined criteria, and 4) outputting accumulated dose and dose-accuracy volume histograms and parameters...
June 2016: Medical Physics
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