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Parotid Gland Tumor

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https://www.readbyqxmd.com/read/29017678/mammary-analogue-secretory-carcinoma-of-parotid-gland-in-a-teenage-boy
#1
Humera Mahmood, Hadia Fatima, Mohammad Faheem
Mammary analogue secretory carcinoma (MASC) is a rare salivary gland malignancy that exhibits resemblance with secretory carcinoma of the breast (SC) due to the presence of ETV6-NTRK3 gene fusion, formerly classified as acinic cell carcinoma. It is a slowly growing painless tumor that exhibits wide range of clinical behavior. This tumor typically affects middle aged people. Less than 100 such cases have been reported in the literature so far with only 8 case reports of patients less than 19 years of age. Very little is known about the clinical management of such cases...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28990673/clinical-characteristics-and-outcomes-of-major-salivary-gland-malignancies-in-children
#2
Shannon Radomski, Sarah Dermody, Earl H Harley
OBJECTIVES/HYPOTHESIS: Determine demographics, clinical characteristics, and survival rates for children with primary salivary gland malignancies. STUDY DESIGN: Retrospective, population-based cohort study. METHODS: All cases of primary salivary gland malignancies diagnosed between the years of 2002 and 2013 in patients ages 0 to 19 years were extracted from the National Cancer Institute's Surveillance, Epidemiology, and End Results database...
October 9, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28987676/value-of-diffusion-tensor-imaging-in-differentiating-malignant-from-benign-parotid-gland-tumors
#3
Koji Takumi, Yoshihiko Fukukura, Hiroto Hakamada, Junichi Ideue, Yuichi Kumagae, Takashi Yoshiura
PURPOSE: To evaluate whether diffusion tensor imaging (DTI) can be used to differentiate malignant parotid gland tumors from the benign ones. MATERIALS AND METHODS: The study population comprised 59 parotid gland tumors (24 Warthin's tumors, 19 pleomorphic adenomas, seven other benign tumors, and nine malignant tumors). Single-shot echo-planar DTI was performed with motion-probing gradients along 30 noncollinear directions (b=1000s/mm(2)) at 3.0T. Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values for benign and malignant tumors were compared using the Mann-Whitney U test...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28987229/controversies-in-oral-and-maxillofacial-oncology
#4
REVIEW
Jacob G Yetzer
Imaging studies are essential components of tumor diagnosis, staging, assessing tumor response to neoadjuvant and adjuvant therapies, and postoperative surveillance on completion of definitive treatment. Treatment of early stage clinically node negative oral cavity squamous cell carcinoma is controversial. Approximately 3% of all head and neck tumors arise within the parotid gland and most often within the superficial lobe, lateral to the facial nerve; about 80% are benign and most are pleomorphic adenoma. In patients with dry eyes failing multiple other treatment modalities and facing ongoing pain and loss of vision, microvascular transplant of the submandibular gland is a viable option...
November 2017: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/28978266/parapharyngeal-space-tumor-surgery-using-a-modified-cervical-parotid-approach
#5
Isaku Okamoto, Kiyoaki Tsukahara, Hiroki Sato
OBJECTIVES: The cervical approach to parapharyngeal space tumors is blind in cases involving an approach to the vicinity of the skull base from below. We therefore devised a procedure to improve the safety of surgery in the vicinity of the skull base. METHODS: With this surgical technique, the temporal branch from the main trunk is first identified, as in the case of parotid gland tumor surgery. We then approach the skull base by entering the posterior aspect of the parotid gland tissue from above the temporal branch and anterior auricular space, allowing clear visual confirmation of the upper part of the tumor...
October 5, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28978260/presentation-of-chronic-lymphocytic-leukemia-small-lymphocytic-lymphoma-in-a-warthin-tumor-case-report-and-literature-review
#6
Hadeel Jawad, Peter McCarthy, Gerard O'Leary, Cynthia C Heffron
Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painless mass of the right parotid gland of 2 years duration with recent ulceration of the overlying skin and right cervical lymphadenopathy underwent a surgical resection of parotid mass and biopsy of the periglandular lymph nodes...
October 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28976348/-renal-cell-carcinoma-metastases-in-the-maxillofacial-area-case-series
#7
Sara Ruiz-Oslé, Carlos Prol, Rosa Lardies, Ayman Gaafar, Luis Barbier, Antón Arruza
Renal cell carcinoma is an unpredictable malignancy. Sometimes, metastases are the disease debut. On the other hand, metastases could present years after treatment of the primary tumor. Four clinical cases of atypical metastases in the head and neck location are presented: parotid gland, mandibular bone, attached molar gingiva and masticator space. Physiopathology, clinics, histology and management of metastatic renal cell carcinoma at those anatomical regions are reviewed.
October 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28963786/correlation-between-the-pathology-and-clinical-presentations-in-patients-with-adenoid-cystic-carcinoma-of-the-external-auditory-canal
#8
Hongyan Liu, Yibo Zhang, Ting Zhang, Feitian Li, Chunfu Dai
BACKGROUND: The purpose of this study was to analyze the correlation between the pathology and clinical presentations in patients with adenoid cystic carcinoma (ACC) of the external auditory canal. METHODS: Twenty-nine patients with ACC of the external auditory canal who underwent surgery were retrospectively reviewed. RESULTS: Fifty percent of patients with solid pattern disease had recurrences, followed by those with cribriform (33%) and tubular (0%) pattern...
September 30, 2017: Head & Neck
https://www.readbyqxmd.com/read/28953638/anti-interferon-%C3%AE-autoantibody-associated-disseminated-mycobacterium-abscessus-infection-mimicking-parotid-cancer-with-multiple-metastases-a-case-report
#9
Po-Hsiung Chang, Yu-Chung Chuang
RATIONALE: Among the nontuberculous mycobacteria, Mycobacterium abscessus is a common cause of skin, soft tissue, and bone infections. However, disseminated M. abscessus infection that mimics cancer metastasis with an underlying relatively immunocompetent condition has rarely been reported. PATIENT CONCERNS: A nonsmoking 73-year-old man with an underlying relatively immunocompetent condition reported a 2-month history of a mass in the region of his right parotid gland that had been steadily increasing in size...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28947094/extraskeletal-osteosarcoma-in-the-parotid-gland-a-case-report
#10
Takao Hamamoto, Takashi Kono, Hiromi Furuie, Tsutomu Ueda, Sachio Takeno, Katsuhiro Hirakawa, Koji Arihiro
Extraskeletal osteosarcoma is a very rare tumor and accounts for 4-5% of all osteosarcomas. We describe a 47-year-old Japanese man who presented with a right parotid tumor. The patient underwent total resection with postoperative radiotherapy; however, the tumor recurred in the lung, whereupon he underwent chemotherapy and partial lung resection. After surgery, a hemorrhagic brain metastasis appeared; this tumor was extirpated to prevent bleeding into the brain, after which additional chemotherapy was administered...
September 22, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28943045/prognostic-factors-for-tube-feeding-dependence-after-curative-chemo-radiation-in-head-and-neck-cancer-a-systematic-review-of-literature
#11
REVIEW
Kim Wopken, Hendrik P Bijl, Johannes A Langendijk
BACKGROUND: Tube feeding dependence is a commonly observed debilitating side-effect of curative (chemo-) radiation in head and neck cancer patients that severely affects quality of life. Prevention of this side-effect can be obtained using advanced radiation techniques, such as IMRT. For radiotherapy treatment plan optimization, it has become increasingly important to develop prediction models that enable clinicians to predict the risk of tube feeding dependence for individual patients...
September 21, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28939075/incidence-of-facial-nerve-sacrifice-in-parotidectomy-for-primary-and-metastatic-malignancies
#12
Brian Swendseid, Shawn Li, Jason Thuener, Rod Rezaee, Pierre Lavertu, Nicole Fowler, Chad Zender
INTRODUCTION: The parotid gland may become involved by primary parotid malignancies and secondarily by metastases from other primary sites. Surgical resection of these tumors can be technically challenging due to the intimate relationship of the parotid gland and the facial nerve. The primary aim of this project was to determine the incidence of facial nerve sacrifice in parotidectomy for primary and secondary malignancies of the parotid. METHODS: A retrospective chart review of was performed...
October 2017: Oral Oncology
https://www.readbyqxmd.com/read/28932166/salivary-duct-carcinoma-of-accessory-parotid
#13
Mohammed A Al-Hashim, Nasser A Al-Jazan
Accessory parotid gland (APG) is seen in around 21%-56% of individuals. Tumors of accessory parotid are uncommon with an incidence rate of 1%-8% of all parotid tumors. Ductal carcinoma of APG is rare, so no reported incidence was seen in the literature. However, salivary gland ductal carcinoma is reported to be 1% of all salivary gland neoplasms. We report here a case of salivary duct carcinoma of APG. Clinical presentation, investigation, and management are discussed. A 69-year-old female presented with a history of the left cheek progressive swelling of 6 years' duration...
September 2017: Journal of Family & Community Medicine
https://www.readbyqxmd.com/read/28932028/cytological-spectrum-of-salivary-gland-lesions-and-their-correlation-with-epidemiological-parameters
#14
Vaneet Kaur Sandhu, Upender Sharma, Navtej Singh, Arun Puri
BACKGROUND: The role fine-needle aspiration (FNA) in the diagnosis of salivary gland lesions has evolved over the years. Although clinical and radiological parameters help to narrow the differential diagnosis the tissue diagnosis still remains the gold standard. MATERIALS AND METHODS: This study is from January 2013 to December 2015 in our Department of Pathology where 170 salivary gland lesions were aspirated. The aim of the present study was to analyze adequacy rate in relation to the size of lesion and to evaluate varied cytological spectrum of salivary gland lesions with emphasis on differential diagnosis and to correlate cytological diagnosis with age, gender and anatomical site...
May 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28927073/surgical-treatment-of-parapharyngeal-space-tumors-a-report-of-29-cases
#15
Kei Ijichi, Shingo Murakami
The present study aimed to establish a strategy for parapharyngeal space (PPS) tumor surgery based on preoperative symptoms, clinical signs, imaging and histological examination. A retrospective cohort study was conducted with 29 adult patients who underwent surgery for primary PPS tumors from 2008-2015. The following data was obtained: Preoperative symptoms of the patient, histological type of the tumor, surgical approach and complications. Of the 29 patients who underwent surgery to remove a PPS tumor, 16 presented with neurogenic tumors and 13 with salivary gland tumors...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28917063/accuracy-of-preoperative-fine-needle-aspiration-in-diagnosis-of-malignant-parotid-tumors
#16
Hani Z Marzouki, Mohammed A Altabsh, Mohammed O Albakrei, Talal A Al-Khatib, Mazin A Merdad, Nada J Farsi
To determine the diagnostic accuracy of fine needle aspiration (FNA) for detecting malignant parotid tumors. Methods: We conducted a retrospective study of all patients diagnosed with benign or malignant parotid gland tumors in King Abdulaziz University Hospital,  Jeddah, Saudi Arabia, between January 2004 and May 2015. The records of 65 subjects were obtained. Histopathological findings and data from FNA examinations were obtained from medical records. Twenty-three subjects were excluded due to missing FNA, histopathology results or both...
October 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28913321/mixed-tumor-in-deep-lobe-and-versatility-of-acellular-dermal-matrix
#17
Jin Hwan Byun, Jung Soo Lim, Hye Kyung Lee
Frey's syndrome and infra-auricular depressed deformities are the ones of the most common complications that can occur after total parotidectomy. We report 1 case of pleomorphic adenoma occurred in the deep lobe that obtained good results from using acellular dermal matrix (ADM) after total parotidectomy. A 24-year-old man visited the hospital with oval shape mass in right mandibular angle which of 4 cm in size was found in the deep lobe of right parotid gland from Magnetic resonance imaging scanning and a pleomorphic adenoma was suspected...
June 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28910871/-mucosa-associated-lymphoid-tissue-lymphoma-in-children-and-adolescents-a-clinicopathologic-study-of-5-cases
#18
J Hu, J L Xie, Z J Zhou, X G Zhou
Objective: To investigate the pathological features and clinical manifestations of mucosa-associated lymphoid tissue (MALT) lymphoma in children and adolescents. Methods: Five cases of MALT lymphoma in children were investigated by morphology and immunophenotyping along with clinical follow-up. Results: Five cases of MALT lymphoma occurred in the antrum, orbit, parotid gland and nasopharynx. All patients had no B symptoms and only one patient showed a local mass with ulcer. One case presented with cervical lymph node enlargement, and 4 cases showed no evidence of lymphadenopathy...
September 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28903405/uptake-of-psma-ligands-in-normal-tissues-is-dependent-on-tumor-load-in-patients-with-prostate-cancer
#19
Florian C Gaertner, Khalil Halabi, Hojjat Ahmadzadehfar, Stefan Kürpig, Elisabeth Eppard, Charalambos Kotsikopoulos, Nikolaos Liakos, Ralph A Bundschuh, Holger Strunk, Markus Essler
Radioligand therapy (RLT) with Lu-177-labeled PSMA-ligands is a new therapy option for prostate cancer. Biodistribution in normal tissues is of interest for therapy planning. We evaluated if the biodistribution of Ga-68-PSMA-11 is influenced by tumor load. RESULTS: In patients with high tumor load, SUVmean was reduced to 61.5% in the lacrimal glands, to 56.6% in the parotid glands, to 63.7% in the submandibular glands, to 61.3% in the sublingual glands and to 55.4% in the kidneys (p < 0...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28900549/myoepithelioma-of-the-parotid-gland-a-case-report-with-review-of-the-literature-and-classic-histopathology
#20
Mark Weitzel, Jason E Cohn, Harvey Spector
Myoepithelioma is a rare salivary gland neoplasm. They most commonly affect the major and minor salivary glands with the parotid gland being the most common, approximately 40%. Only 1% of all salivary gland neoplasms are myoepitheliomas. Myoepithelioma is usually a benign tumor arising from neoplastic myoepithelial or basket cells which are found between the basement membrane and the basal plasma membrane of acinar cells. They also contain multiple cellular elements. We present a case of a 73-year-old female with myoepithelioma of the parotid gland, an extremely rare neoplasm...
2017: Case Reports in Otolaryngology
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