Read by QxMD icon Read

Parotid Gland Tumor

Yuki Sakamoto, Shuichi Fujita, Masaki Adachi, Hiroshi Sakamoto, Tomofumi Naruse, Souichi Yanamoto, Toru Ikeda, Masahiro Umeda
Carcinoma ex pleomorphic adenoma (CEPA) is a carcinoma that shows histologic evidence of arising in or from a benign pleomorphic adenoma. Carcinoma ex pleomorphic adenoma often occurs in parotid glands, but is extremely rarely in the tongue. A 53-year-old Japanese woman was referred to the Department of Oral and Maxillofacial Surgery, Nagasaki University Hospital, because of tumor of the right dorsum tongue. She had a history of surgery of breast cancer (invasive ductal carcinoma) and it was disseminated to the lung and bone...
October 14, 2016: Journal of Craniofacial Surgery
Min-Hui Hung, Chun-Ta Liao, Chung-Jan Kang, Shiang-Fu Huang
Most parotid tumors grow slowly, and sometimes these patients do not request surgical treatment until the tumors become large and affect their appearance. The surgical treatment of these large tumors is usually accompanied by large skin defects after excision, and it is challenging for surgeons to close the defect primarily. This report describes the case of a 68-year-old man with a left parotid gland tumor (largest dimension, 110 mm) and the case of a 79-year-old man with a left parotid gland tumor measuring approximately 77 mm that had existed for decades...
September 21, 2016: Journal of Oral and Maxillofacial Surgery
Ali Khalife, Mehdi Bakhshaee, Behrouz Davachi, Leila Mashhadi, Kamran Khazaeni
INTRODUCTION: Different imaging modalities are used to evaluate salivary gland diseases, including tumors. Ultrasonography (US) is the preferred method on account of its ease of use, affordability, safety profile, and good tolerance among patients. The aim of this study was to evaluate the role of US in differentiating malignant from benign parotid tumors, in the context of previous controversy in the literature on this subject. MATERIALS AND METHODS: A cross-sectional study was performed in patients who presented to Qaem Medical Center with parotid masses and who were candidates for parotidectomy between June 2013 and January 2015...
September 2016: Iranian Journal of Otorhinolaryngology
Matthew L Carlson, Nicholas L Deep, Neil S Patel, Larry B Lundy, Nicole M Tombers, Christine M Lohse, Michael J Link, Colin L Driscoll
OBJECTIVE: To elucidate the long-term clinical behavior, treatment, and outcomes of sporadic facial nerve schwannoma (FNS) in a large cohort of patients managed in the post-magnetic resonance imaging era. PATIENTS AND METHODS: Retrospective review at a single tertiary health care system (January 1, 1990, through December 31, 2015), evaluating 80 consecutive patients with sporadic FNS. RESULTS: Ninety-eight patients with FNS were identified; 10 with incomplete data and 8 with neurofibromatosis type 2 were excluded...
October 5, 2016: Mayo Clinic Proceedings
Lorenz Kadletz, Stefan Grasl, Matthäus C Grasl, Christos Perisanidis, Boban M Erovic
BACKGROUND: The purpose of this study was to evaluate the clinical outcome in patients with benign parotid gland tumors after extracapsular dissection or superficial parotidectomy (SP). METHODS: Eight hundred ninety-four patients with primary pleomorphic adenoma or Warthin's tumor were included from this study. Type and length of surgery, tumor size, resection margins, and complication rates were assessed. RESULTS: Three hundred ninety-five (44...
October 5, 2016: Head & Neck
Justin T Easley, Christina L M Maruyama, Ching-Shuen Wang, Olga J Baker
Sjögren's syndrome (SS) is an autoimmune disorder characterized by chronic inflammation and destruction of salivary and lacrimal glands leading to dry mouth and dry eyes, respectively. Currently, the etiology of SS is unknown and the current therapies have no permanent benefit; therefore, new approaches are necessary to effectively treat this condition. Resolvins are highly potent endogenous lipid mediators that are synthesized during the resolution of inflammation to restore tissue homeostasis. Previous studies indicate that the resolvin family member, RvD1, binds to the ALX/FPR2 receptor to block inflammatory signals caused by tumor necrosis factor-alpha (TNF-α) in the salivary epithelium...
October 2016: Physiological Reports
Silvia Potenziani, Danielle Applebaum, Bhuvaneswari Krishnan, Carolina Gutiérrez, A Hafeez Diwan
Cowden Syndrome (CS) is an uncommon autosomal dominant multiorgan/system genodermatosis. It is characterized by the development of multiple hamartomas of endodermal, mesodermal and ectodermal origin, an increased lifetime risk of breast, thyroid, endometrial, and other cancers and an identifiable germline mutation. Mucocutaneous hamartomas are the most common lesions seen and mainly include facial trichilemmomas, oral mucosal papillomas, and benign acral keratoses. Herein, we report a case of a 63-year-old Caucasian male with a long-established diagnosis of CS and history of thyroid cancer, colonic polyps, and innumerable trichilemmomas, seborrheic keratoses, squamous papillomas, and non-melanoma skin cancers excised in the past...
September 28, 2016: Journal of Cutaneous Pathology
Stuart E Samuels, Avraham Eisbruch, Karen Vineberg, Jae Lee, Choonik Lee, Martha M Matuszak, Randall K Ten Haken, Kristy K Brock
PURPOSE: Strategies to reduce the toxicities of head and neck radiation (ie, dysphagia [difficulty swallowing] and xerostomia [dry mouth]) are currently underway. However, the predicted benefit of dose and planning target volume (PTV) reduction strategies is unknown. The purpose of the present study was to compare the normal tissue complication probabilities (NTCP) for swallowing and salivary structures in standard plans (70 Gy [P70]), dose-reduced plans (60 Gy [P60]), and plans eliminating the PTV margin...
November 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Michael Coulter, Jingxuan Liu, Mark Marzouk
There is only one previously reported incident in the English literature of sarcoma ex pleomorphic adenoma of the parotid and there are only 8 cases of primary parotid leiomyosarcoma. In our case, a 79-year-old female patient presented to our care with left preauricular pain, swelling, and facial weakness. After CT imaging, she underwent left total parotidectomy. A spindle cell lesion was identified intraoperatively and the facial nerve was sacrificed. Subsequent analysis of the lesion yielded a diagnosis of leiomyosarcoma ex pleomorphic adenoma...
2016: Case Reports in Otolaryngology
Shozo Okamoto, Anne Thieme, Jakob Allmann, Calogero D'Alessandria, Tobias Maurer, Margitta Retz, Robert Tauber, Matthias M Heck, Hans-Juergen Wester, Nagara Tamaki, Wolfgang P Fendlder, Ken Herrmann, Christian H Pfob, Klemens Scheidhauer, Markus Schwaiger, Sibylle Ziegler, Matthias Eiber
PURPOSE: Prostate-specific membrane antigen (PSMA) targeted radioligand therapy (RLT) is increasingly used in metastatic castration-resistant prostate cancer (mCRPC). We aimed to estimate the absorbed doses for normal organs and tumor lesions using (177)Lu-PSMA-I&T in patients undergoing up to four cycles RLT. Results were compared to pre-therapeutic (68)Ga-PSMA-HBED-CC positron-emission-tomography (PET). METHODS: A total of 34 cycles in 18 patients were analyzed retrospectively...
September 22, 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
Anja Lieder, Thomas Guenzel, Steffen Lebentrau, Constanze Schneider, Achim Franzen
PURPOSE: Renal cell carcinoma (RCC) is a malignant tumor that metastasizes early, and patients often present with metastatic disease at the time of diagnosis. The aim of our evaluation was to assess the diagnostic and differential diagnostic relevance of metastatic renal cell carcinoma (RCC) with particular emphasis on head and neck manifestations in a large patient series. PATIENTS AND METHODS: We retrospectively evaluated 671 consecutive patients with RCC who were treated in our urology practice between 2000 and 2013...
September 20, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Peter Grzesik, Cary Passik, Amirhossein Mahfoozi
Sialadenoma papilliferum is a tumor of salivary gland origin. It is believed that sialadenoma papilliferum is a benign lesion usually known to occur in the hard palate, retromolar fat pads, lips, and parotid glands. Its origin in the bronchial tree is an extremely rare occurrence. We report only the fourth known case of bronchial sialadenoma papilliferum and the first to originate in the trachea. The patient underwent successful resection of the lesion, with complete relief of his dyspnea.
October 2016: Annals of Thoracic Surgery
Uday Shankar Yaga, Nishanth Gollamudi, Ashwini Kumar Mengji, Radhika Besta, Prashanth Panta, Bhanu Prakash, Edunuri Rajashekar
Adenoid Cystic Carcinoma (ACC) is a rare tumor constitutes for less than 1% of head and neck malignancies and 10% of all salivary gland tumors. Palate is the most common site to be involved in the oral cavity followed by parotid gland and submandibular gland. They are usually asymptomatic, slow growing, characteristically shows infiltrative growth and perineural invasion. This paper reports a case of Adenoid Cystic Carcinoma in a 35 year old female man reported with a swelling on the left side of palate involving the hard and soft palate since 8 months which was diagnosed histopathologically and review of literature of the peculiar clinical, and histopathological features...
2016: Pan African Medical Journal
Nobuo Kashiwagi, Takamichi Murakami, Masafumi Toguchi, Katsuyuki Nakanishi, Shojiro Hidaka, Hideyuki Fukui, Masatomo Kimura, Mutsukazu Kitano, Noriyuki Tomiyama
OBJECTIVES: To present and characterize CT and MR imaging findings of metastases to the parotid nodes. METHODS: CT (n = 10) and MR (n = 11) images from 14 patients with metastases to the parotid nodes were reviewed. The primary tumour sites were the ocular adnexa in five patients, facial skin in four patients, upper aerodigestive tract in four patients and thyroid gland in one patient. CT and MR images were evaluated with emphasis on the size and number of parotid tumours, their location in the parotid gland, the presence of associated clinically pathological cervical nodes or previous history of cervical node metastasis, margin characteristics and the presence of central necrosis...
October 11, 2016: Dento Maxillo Facial Radiology
Olga Martínez-Sáez, Javier Molina-Cerrillo, Carmen Moreno García Del Real, Rafael Barberá Durban, Juan J Díez, Teresa Alonso-Gordoa, Enrique Grande Pulido
Neuroendocrine tumors (NETs) comprise a heterogeneous group of malignancies from cells derived from the neural crest with neuroendocrine differentiation. Despite the differences in the site of origin, nomenclature, biological behavior, and functional status, NETs share certain ultrastructural and immunohistochemical features. NETs are relative rare tumors with an annual incidence of 5.76 new cases per 100.000 inhabitants and they usually appear in the gastrointestinal tract or in the pulmonary system. Head and neck NETs are uncommon with limited information regarding frequency, most of them showing small cell carcinoma features...
2016: Case Reports in Otolaryngology
Farahnaz Bidari-Zerehpoosh, Bijan Naghibzadeh, Elena Jamali, Moein Jamali, Amirali Mafi, Hooman Bahrami-Motlagh
INTRODUCTION: Mucoepidermoid carcinoma represents one of the most common malignant salivary gland tumors. However, the sclerosing morphologic variant is extremely rare with only 23 reported cases in the English-language literature since it was discovered in 1987. CASE REPORT: Herein, we describe another case that was diagnosed in a 25-year-old woman presenting with a posterior auricular mass, as well as a review of the literature, which demonstrates that this is an extremely rare malignancy with no strict protocol for treatment...
July 2016: Iranian Journal of Otorhinolaryngology
Ritika Singh, Sufian Zaheer, Ashish K Mandal
Primary osteoclast-like giant cell tumor (OC-GCT) has been rarely described in extraskeletal sites. The diagnosis primarily hinges on the detection of giant cells. However, these giant cells are also seen in many giant cell lesions, thus creating diagnostic confusion and dilemma. Here, we describe a rare case of a 24-year-old male with primary extraskeletal, OC-GCT presenting as a swelling in the right parotid region and highlight its cytological, histological and immunohistochemical characteristics with diagnostic challenges...
May 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
Archana Shetty, V Geethamani
INTRODUCTION: Neoplastic lesions of salivary glands present an interesting subject because of their histologic diversification. Complex features exhibited by them have aroused considerable speculations concerning their histogenesis and continues to hold the interest of clinicians and pathologists. Major salivary glands are superficial and have easy accessibility for fine-needle aspiration cytology (FNAC). These glands are generally not subjected to incisional or core needle biopsy, because of the possible risks of fistula formation and tumor seedling...
May 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
Hélios Bertin, Raphael Bonnet, Anne-Sophie Delemazure, Emmanuelle Mourrain-Langlois, Jacques Mercier, Pierre Corre
OBJECTIVE: Non-tumor salivary diseases are common. Imaging studies are essential for their diagnosis and before undergoing an endoscopic or surgical treatment. In this study we aimed at presenting our procedure and results obtained with three dimensional cone-beam CT (3D-CBCT) sialography for non-tumor salivary gland diseases. METHODS: Patients with parotid or submandibular salivary symptoms were examined by 3D-CBCT sialography. They received an intraductal injection of 0...
September 2, 2016: Dento Maxillo Facial Radiology
Eric C Huang, Varand Ghazikhanian, Xiaohua Qian
Giant cell-rich osteosarcoma is a rare histologic variant of conventional osteosarcoma that affects mainly the extremities. Extraskeletal giant cell-rich osteosarcoma is therefore exceedingly rare. Here, we report the first case of this uncommon tumor involving the parotid gland in a 62-year-old male who presented with initial right jaw swelling. Radiologic work-up revealed a 6.2 cm mass involving the right parotid gland. Fine-needle aspiration cytology showed numerous multinucleated giant cells in a background of dyshesive epithelioid cells and rare clusters of spindle stromal cells, suspicious for malignancy...
August 26, 2016: Diagnostic Cytopathology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"