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Parotid Gland Tumor

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https://www.readbyqxmd.com/read/28076460/the-accuracy-of-fine-needle-aspiration-cytology-for-diagnosis-of-parotid-gland-masses-a-clinicopathological-study-of-114-patients
#1
Jens Kristjan Gudmundsson, Aida Ajan, Jahan Abtahi
Objective: Fine-needle aspiration cytology is a valuable method for preoperative assessment of head and neck tumors. However, its accuracy in detection of salivary gland masses is controversial compared with other methods. The aim of this work was to evaluate the effectiveness and accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of parotid gland masses. Material and Methods: Over a 10-year period, 126 parotid gland masses were resected. Retrospective chart reviews of 114 patients were performed...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28074380/usefulness-of-diffusion-weighted-mr-imaging-for-differentiating-between-warthin-s-tumor-and-oncocytoma-of-the-parotid-gland
#2
Hiroki Kato, Keita Fujimoto, Masayuki Matsuo, Keisuke Mizuta, Mitsuhiro Aoki
PURPOSE: To assess the efficacy of diffusion-weighted (DW) MR imaging for differentiating between Warthin's tumor and oncocytoma of the parotid gland. METHODS: Forty-five histopathologically confirmed parotid gland tumors (41 Warthin's tumors and 4 oncocytomas) were examined by MR imaging including DW imaging. (18)F-fluorodeoxyglucose PET/CT was also performed in 9 Warthin's tumors and 3 oncocytomas. We retrospectively reviewed the images and compared the MR signal intensities, apparent diffusion coefficients (ADCs), and maximum standardized uptake values (SUVmax) of the solid components between the two pathologies...
January 10, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28071626/prognostic-factors-in-postoperative-radiotherapy-in-salivary-gland-carcinoma-a-single-institution-experience-from-turkey
#3
M Kandaz, G Soydemir, Z Bahat, E Canyılmaz, A Yöney
BACKGROUND: We reviewed clinical characteristics, treatment outcomes, local and distant failure and prognostic factors in patients with salivary gland carcinoma treated with surgery and postoperative radiotherapy. MATERIALS AND METHODS: We retrospectively reviewed 75 patients with salivary gland cancer. 69 (%92) patients had cancer of the parotid gland, 3 (%4) patients had cancer of the submandibular gland and 3 (%4) patients had cancer of the minor salivary gland...
April 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28055973/outcome-and-long-term-efficacy-of-four-facio-cervical-fields-conformal-radiotherapy-for-nasopharyngeal-carcinoma
#4
Wang Fangzheng, Jiang Chuner, Wang Lei, Chen Weijun, Xu Min, Sun Quanquan, Liu Tongxin, Rihito Aizawa, Masoto Sakamoto, Fu Zhenfu
PURPOSE: To evaluate the outcomes of 255 patients with nasopharyngeal carcinoma (NPC) treated with four facio-cervical fields conformal radiotherapy (4F-CRT). RESULTS: In one patient's 3 different RT treatment modalities, the 4F-CRT techniques resulted in sharper of the dose-volume histograms (DVHs) for primary gross tumor volume (PGTVnx) and planning target volume (PTVnx), similar to the intensity modulated radiation therapy (IMRT). The median follow-up duration was 43 months...
December 31, 2016: Oncotarget
https://www.readbyqxmd.com/read/28050002/pulmonary-tumor-thrombotic-microangiopathy-caused-by-a-parotid-tumor-early-antemortem-diagnosis-and-long-term-survival
#5
Haruka Toyonaga, Michiko Tsuchiya, Chikara Sakaguchi, Hitomi Ajimizu, Yosuke Nakanishi, Seiya Nishiyama, Noboru Morikawa, Yasuyuki Hayashi, Yukio Nagasaka, Hiroshi Yasui
Pulmonary tumor thrombotic microangiopathy (PTTM) is a high-mortality disease that is difficult to diagnose clinically. Our patient was an 80-year-old woman who came to us due to symptoms of increasing dyspnea. A clinical evaluation showed that she had hypoxemia and pulmonary arterial hypertension without any abnormalities in the major pulmonary arteries, bronchi, or alveoli. A lung perfusion scan showed multiple wedge-shaped perfusion defects. Further examination revealed adenocarcinoma in her right parotid gland with metastasis to the submandibular lymph nodes...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28048629/tu-h-campus-jep2-04-deriving-delivered-doses-to-assess-the-viability-of-2-5-mm-margins-in-head-and-neck-sbrt
#6
S Lin, Q Shang, S Pirozzi, A Godley
PURPOSE: To calculate the delivered dose for head and neck SBRT patients using pre-treatment images. This delivered dose was then used to determine the viability of 2.5 mm margins. METHODS: Daily cone beam CTs (CBCTs) were collected for 20 patients along with a planning CT, planned dose, and planning structures. The day 1 CBCT was aligned to the planning CT using the treatment shifts (six degrees of freedom) and then the dose and contours were transferred to the CBCT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048228/su-f-p-26-study-of-radiation-dose-evaluation-for-organs-at-risk-using-mri-in-intensity-modulated-radiation-therapy-for-nasopharyngeal-carcinoma
#7
G Gong, Y Guo, Y Yin
PURPOSE: To study the contour and dosimetric feature of organs at risk (OARs) applying magnetic resonance imaging (MRI) images in intensity modulated radiation therapy (IMRT) of nasopharyngeal carcinoma (NPC) compared to computed tomography (CT) images. METHODS: 35 NPC patients was selected into this trail. CT simulation with non-contrast and contrast enhanced scan, MRI simulation with non-contrast and contrast enhanced T1, T2 and diffusion weighted imaging were achieved sequentially...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047821/su-f-t-523-radiobiological-comparison-of-helical-tomotherapy-and-vmat-in-the-treatment-of-head-and-neck-tumors
#8
R Woods, P Mavroidis, M Lehman-Davis, M Kostich, T Cook, B Chera, S Das, J Lian
PURPOSE: This study aims at comparing the efficacy of Helical Tomotherapy (TOMO) and Volumetric Modulated Arc Therapy (VMAT) in producing highly conformal dose distributions in challenging head & neck cancer patients. Furthermore, to interpret the dosimetric findings into expected tissue response rates in order to estimate their clinical impact. METHODS: Seven patients were studied and for each patient two treatment plans (one TOMO and one VMAT) were created. Structures used for optimization were: high risk PTV, standard risk PTV, brainstem, spinal cord, parotid gland, larynx, mandible and surrounding tissue...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047089/th-cd-206-05-machine-learning-based-segmentation-of-organs-at-risks-for-head-and-neck-radiotherapy-planning
#9
B Ibragimov, F Pernus, P Strojan, L Xing
PURPOSE: Accurate and efficient delineation of tumor target and organs-at-risks is essential for the success of radiotherapy. In reality, despite of decades of intense research efforts, auto-segmentation has not yet become clinical practice. In this study, we present, for the first time, a deep learning-based classification algorithm for autonomous segmentation in head and neck (HaN) treatment planning. METHODS: Fifteen HN datasets of CT, MR and PET images with manual annotation of organs-at-risk (OARs) including spinal cord, brainstem, optic nerves, chiasm, eyes, mandible, tongue, parotid glands were collected and saved in a library of plans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047063/tu-h-campus-jep3-02-automated-dose-accumulation-and-dose-accuracy-assessment-for-online-or-offline-adaptive-replanning
#10
G Chen, E Ahunbay, X Li
PURPOSE: With introduction of high-quality treatment imaging during radiation therapy (RT) delivery, e.g., MR-Linac, adaptive replanning of either online or offline becomes appealing. Dose accumulation of delivered fractions, a prerequisite for the adaptive replanning, can be cumbersome and inaccurate. The purpose of this work is to develop an automated process to accumulate daily doses and to assess the dose accumulation accuracy voxel-by-voxel for adaptive replanning. METHODS: The process includes the following main steps: 1) reconstructing daily dose for each delivered fraction with a treatment planning system (Monaco, Elekta) based on the daily images using machine delivery log file and considering patient repositioning if applicable, 2) overlaying the daily dose to the planning image based on deformable image registering (DIR) (ADMIRE, Elekta), 3) assessing voxel dose deformation accuracy based on deformation field using predetermined criteria, and 4) outputting accumulated dose and dose-accuracy volume histograms and parameters...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046893/su-d-204-05-fitting-four-ntcp-models-to-treatment-outcome-data-of-salivary-glands-recorded-six-months-after-radiation-therapy-for-head-and-neck-tumors
#11
P Mavroidis, A Price, M Kostich, R Amdur, W Mendenhall, N Sheets, R Green, S Das, L Marks, B Chera
PURPOSE: To estimate the radiobiological parameters of four popular NTCP models that describe the dose-response relations of salivary glands to the severity of patient reported dry mouth 6 months post chemo-radiotherapy. To identify the glands, which best correlate with the manifestation of those clinical endpoints. Finally, to evaluate the goodness-of-fit of the NTCP models. METHODS: Forty-three patients were treated on a prospective multiinstitutional phase II study for oropharyngeal squamous cell carcinoma...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28028340/diffuse-large-b-cell-lymphoma-of-the-parotid-gland-cytological-histopathological-and-immunohistochemical-features-a-rare-case-report
#12
Sainath K Andola, Meenakshi M Masgal, Rajeev M Reddy
Primary malignant lymphomas of the salivary glands are rare, accounting for 2-5% of salivary gland tumors and 5% of extranodal lymphomas, frequently seen in the parotid gland. There are single case reports mentioned in the literature. Clinical presentation is not characteristic and the disease is often overlooked with delay in diagnosis and treatment. We are reporting a case of bilateral parotid gland lymphoma in a 55-year-old male, presented with bilateral enlarged parotids. Magnetic resonance imaging (MRI) showed bilateral enlarged parotid glands with multiple well-defined intraparotid lesions...
October 2016: Journal of Cytology
https://www.readbyqxmd.com/read/28013343/warthin-tumor-within-the-superficial-lobe-of-the-parotid-gland-a-suggested-criterion-for-diagnosis
#13
Doron Sagiv, Robert L Witt, Eran Glikson, Jobran Mansour, Bruria Shalmon, Arkadi Yakirevitch, Michael Wolf, Eran E Alon, Guy Slonimsky, Yoav P Talmi
The location of Warthin tumor (WT) in the parotid gland impacts the surgical approach and may be indicative of the elusive origin of this intriguing entity. Location in the deep versus superficial lobe of the gland is not directly addressed when defining WT characteristics. Our observation, of rare occurrence of deep lobe WT, if at all, led to the current investigation. The study design is cohort study. This is a retrospective chart review of all patients undergoing parotidectomy for WT in two tertiary academic referral centers: the Sheba Medical Center (SMC), Israel, and the Christiana Care (CC), Newark, Delaware, USA...
December 24, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28006083/definitive-carbon-ion-radiotherapy-for-locally-advanced-parotid-gland-carcinomas
#14
Masashi Koto, Azusa Hasegawa, Ryo Takagi, Hiroaki Ikawa, Kensuke Naganawa, Jun-Etsu Mizoe, Keiichi Jingu, Hirohiko Tsujii, Hiroshi Tsuji, Tadashi Kamada, Yoshitaka Okamoto
BACKGROUND: The purpose of this study was to present our evaluation of the safety and efficacy of carbon-ion radiotherapy (C-ion RT) for locally advanced parotid gland carcinomas. METHODS: Clinicopathological features and outcomes were evaluated in 46 patients receiving C-ion RT for parotid gland carcinomas. RESULTS: Sixteen patients had adenoid cystic carcinoma; 8 had adenocarcinoma, 8 had mucoepidermoid carcinoma, and 14 had other carcinomas...
December 22, 2016: Head & Neck
https://www.readbyqxmd.com/read/28002989/fine-needle-aspiration-cytology-fnac-is-it-useful-in-preoperative-diagnosis-of-parotid-gland-lesions
#15
Inês Correia-Sá, Mário Correia-Sá, Pedro Costa-Ferreira, Álvaro Silva, Marisa Marques
BACKGROUND: Salivary gland tumors are an uncommon entity and its histopathology is highly varied due to heterogeneous cellular composition. The role of the preoperative fine-needle aspiration cytology (FNAC) remains controversial. The purpose of this study is to compare the cytologic findings of salivary gland lesions with the histologic diagnoses, in order to assess the usefulness and accuracy of fine-needle aspiration cytology in the diagnosis of parotid gland tumors. METHODS: A retrospective study was performed, regarding patients (n = 65) submitted to surgery for the treatment of parotid gland disease, who had performed preoperative FNAC, in our department between 2002 and 2012...
December 21, 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28001329/fna-biopsy-of-secondary-nonlymphomatous-malignancies-in-salivary-glands-a-multi-institutional-study-of-184-cases
#16
He Wang, Raza S Hoda, William Faquin, Esther Diana Rossi, Nihar Hotchandani, Tianlin Sun, Marc Pusztaszeri, Tommaso Bizzarro, Massimo Bongiovanni, Viren Patel, Nirag Jhala, Guido Fadda, Yun Gong
BACKGROUND: Secondary malignancies of salivary glands (SMSGs) are among the most common malignant neoplasms to involve the salivary glands. Fine-needle aspiration biopsy (FNAB) of SMSG can present diagnostic challenges. The current report presents the largest such FNAB series to date. METHODS: A search of the pathology database from 6 academic institutions identified 184 FNAB cases of nonlymphomatous SMSG. RESULTS: Of the 184 cases, 171 were of the parotid glands, and 13 were of the submandibular glands; 130 patients were men, and 54 were women, and the mean patient age at diagnosis was 68 years...
December 21, 2016: Cancer
https://www.readbyqxmd.com/read/27997063/investigation-of-arguments-against-properly-indicated-extracapsular-dissection-in-the-parotid-gland
#17
Konstantinos Mantsopoulos, Claudia Scherl, Heinrich Iro
BACKGROUND: The ideal extent of surgical intervention for benign parotid tumors remains a matter of controversy. The purpose of this study was to examine the existing arguments against extracapsular dissection and present our experience over the last 16 years. METHODS: A retrospective evaluation was carried out on the records of all patients who underwent extracapsular dissection for benign parotid tumors at a tertiary referral center between 2000 and 2015. RESULTS: A total of 1359 cases were included in the study...
December 20, 2016: Head & Neck
https://www.readbyqxmd.com/read/27960047/incidence-and-risk-factors-of-late-recurrence-in-patients-with-salivary-gland-cancer
#18
G C Park, J-L Roh, K-J Cho, M H Jin, S-H Choi, S Y Nam, S Y Kim
OBJECTIVES: Recurrence in the late post-treatment period is relatively common in salivary gland cancer (SGC), but risk factors and survival associated with late recurrence have been rarely studied. We investigated the incidence and risk factors of SGC recurrence >5 years after treatment and associated survival. DESIGN: A retrospective cohort study. SETTING: University hospital. PARTICIPANTS: A total of 240 patients with previously untreated SGC who underwent definitive treatment...
December 13, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27957284/report-of-a-case-of-acinic-cell-carcinoma-of-the-upper-lip-and-review-of-japanese-cases-of-acinic-cell-carcinoma-of-the-minor-salivary-glands
#19
Shigeo Ishikawa, Hitoshi Ishikawa, Shigemi Fuyama, Takehito Kobayashi, Takayoshi Waki, Yukio Taira, Mitsuyoshi Iino
Acinic cell carcinoma (ACC) is a malignant tumor of the salivary glands. The majority of ACCs occur in the parotid gland, and ACCs of the minor salivary glands (MSGs) are relatively infrequent. We describe here a patient with ACC of the upper lip. The patient was a 31-year-old male who presented with a nodular mass on the left upper lip. The preoperative diagnosis was benign tumor or cyst, and the lesion was surgically excised. The histological diagnosis was ACC. The postoperative course was uneventful. No recurrence or metastasis was detected at 13 months postoperatively...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27935126/does-cell-phone-use-increase-the-chances-of-parotid-gland-tumor-development-a-systematic-review-and-meta-analysis
#20
REVIEW
Elisa Carvalho de Siqueira, Fabrício Tinoco Alvim de Souza, Ricardo Santiago Gomez, Carolina Cavalieri Gomes, Renan Pedra de Souza
BACKGROUND: Prior epidemiological studies had examined the association between cell phone use and the development of tumors in the parotid glands. However there is no consensus about the question of whether cell phone use is associated with increased risk of tumors in the parotid glands. We performed a meta-analysis to evaluate the existing literature about the mean question and to determine their statistical significance. METHODS: Primary association studies. Papers that associated cell phone use and parotid gland tumors development were included, with no restrictions regarding publication date, language and place of publication...
December 9, 2016: Journal of Oral Pathology & Medicine
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