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Infectious chronic sinusitis

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https://www.readbyqxmd.com/read/27879058/sinus-surgery-can-improve-quality-of-life-lung-infections-and-lung-function-in-patients-with-primary-ciliary-dyskinesia
#1
Mikkel Christian Alanin, Kasper Aanaes, Niels Høiby, Tania Pressler, Marianne Skov, Kim Gjerum Nielsen, Helle Krogh Johansen, Christian von Buchwald
BACKGROUND: Chronic rhinosinusitis (CRS) and bacterial sinusitis are ubiquitous in patients with primary ciliary dyskinesia (PCD). From the sinuses, Pseudomonas aeruginosa can infect the lungs. METHODS: We studied the effect of endoscopic sinus surgery (ESS) on symptoms of CRS and lower airway infections in PCD patients in a prospective single-arm intervention study of ESS with adjuvant therapy using nasal irrigation with saline, topical nasal steroids, and 2 weeks of systemic antibiotics...
November 23, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27833296/three-rare-cases-of-cutaneous-phaeohyphomycosis
#2
Aditi Chhonkar, Deepti Kataria, Swagata Tambe, Chitra S Nayak
Phaeohyphomycosis is a chronic infectious condition caused by dematiaceous fungi which usually involve the skin and subcutaneous tissue. Subcutaneous phaeohyphomycosis is characterised by papulonodules, verrucous, hyperkeratotic or ulcerated plaques, cysts, abscesses, pyogranuloma, non-healing ulcers or sinuses. In India, commonly associated genera are Exophiala, Phialophora, Cladosporium, Curvularia, Fonsecaea and Alternaria. This condition involves the presence of brown-walled hyphal structures in the dermis and epidermis...
May 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/27598436/a-chronic-rhinosinusitis-derived-isolate-of-pseudomonas-aeruginosa-induces-acute-and-pervasive-effects-on-the-murine-upper-airway-microbiome-and-host-immune-response
#3
Emily K Cope, Andrew N Goldberg, Steven D Pletcher, Susan V Lynch
BACKGROUND: Diverse microbial communities colonize healthy sinus mucosa and specific species within these communities are capable of protecting the host from pathogenic infection. However, little is known of the dynamics of upper airway infection and the role of the sinus mucosal microbiome in short- and longer-term outcomes using clinical isolates from patients with chronic rhinosinusitis. METHODS: We examine microbiome and immune dynamics after murine sinus infection with Pseudomonas aeruginosa EC1, isolated previously from a chronic rhinosinusitis patient...
September 6, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27456595/association-of-oral-flora-with-orbital-complications-of-acute-sinusitis
#4
Juliette O Flam, Michael P Platt, Rachel Sobel, Anand K Devaiah, Christopher D Brook
BACKGROUND: Acute and chronic sinusitis in children and adults can spread to the orbit. Oral flora has been seen in orbital infections, but the extent of synergy between pathogens in such infections remains unknown. METHODS: A retrospective case series of patients with complicated sinusitis that involved the orbit from acute sinusitis who were admitted to a tertiary care hospital from January 2000 to December 2014 and who had surgical cultures obtained. Patients were identified by the International Classification of Diseases, Ninth Revision code for periorbital cellulitis, subperiosteal abscess, or orbital abscess...
July 2016: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/27403111/orbital-pseudotumor-as-a-rare-extrahepatic-manifestation-of-hepatitis-c-infection
#5
Benjamin Misselwitz, Jana Epprecht, Joachim Mertens, Luc Biedermann, Michael Scharl, Eugenia Haralambieva, Andreas Lutterotti, Konrad P Weber, Beat Müllhaupt, Karla Chaloupka
Hepatitis C is frequently accompanied by immune-related extrahepatic manifestations affecting the skin, kidneys, central and peripheral nervous system and exocrine glands. We present the case of a 40-year-old man with left-sided ptosis, exophthalmos and headache. MRI demonstrated left-sided orbital pseudotumor with lacrimal and retro-orbital contrast enhancement extending to the cavernous sinus and the vestibulocochlear nerve. Immunological tests of serum and cerebrospinal fluid identified hepatitis C virus (HCV) as a potential causative agent but did not indicate any additional infectious, malignant or immunological disorder...
January 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27252811/bilateral-maxillary-sphenoid-sinuses-and-lumbosacral-spinal-cord-extramedullary-relapse-of-cml-following-allogeneic-stem-cell-transplant
#6
Soudabeh Hosseini, Shahla Ansari, Parvaneh Vosough, Gholamreza Bahoush, Amir Ali Hamidieh, Bahram Chahardouli, Morteza Shamsizadeh, Mitra Mehrazma, Akbar Dorgalaleh
Isolated extramedullary relapse of chronic myelogenous leukemia (CML) after allogeneic stem cell transplant is rare. There is a case report of a child who developed a granulocytic sarcoma of the maxillary and sphenoid sinuses and lumbosacral spinal cord mass 18 months after allogeneic bone marrow transplant for CML. He was presented with per orbital edema and neurological deficit of lower extremities and a mass lesion was found on spinal cord imaging. No evidence of hematologic relapse was identified at that time by bone marrow histology or cytogenetic...
April 1, 2016: International Journal of Hematology-oncology and Stem Cell Research
https://www.readbyqxmd.com/read/27240496/pediatric-otitis-media-in-fiji-survey-findings-2015
#7
Te-Yung Fang, Eric Rafai, Pa-Chun Wang, Chiy-Huey Bai, Peng-Long Jiang, Shu-Nuan Huang, You-Ju Chen, Yi-Ting Chao, Chen-Hsu Wang, Chia-Hsiu Chang
OBJECTIVE: Otitis media (OM), as a common infectious disease, is a major cause of hearing impairment among the general population. OM remains a major public health threat in the Pacific islands, but the risks of OM have not been thoroughly explored in this region. The objective of this study is to investigate the prevalence, clinical features, and quality-of-life impacts of OM in Fiji. METHODS: In the medical service trip entitled "Healing and Hope - Taiwan Cathay Heart and Hearing Medical Mission to Fiji" (TCHHMMF), we conducted a cross-sectional OM survey study in Suva and Sigatoka areas (Korolevu, Cuvu, and Lomawai) in the summer of 2015...
June 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27189378/hyper-igm-syndrome-a-report-from-the-usidnet-registry
#8
Emily A Leven, Patrick Maffucci, Hans D Ochs, Paul R Scholl, Rebecca H Buckley, Ramsay L Fuleihan, Raif S Geha, Coleen K Cunningham, Francisco A Bonilla, Mary Ellen Conley, Ronald M Ferdman, Vivian Hernandez-Trujillo, Jennifer M Puck, Kathleen Sullivan, Elizabeth A Secord, Manish Ramesh, Charlotte Cunningham-Rundles
PURPOSE: The United States Immunodeficiency Network (USIDNET) patient registry was used to characterize the presentation, genetics, phenotypes, and treatment of patients with Hyper IgM Syndrome (HIGM). METHODS: The USIDNET Registry was queried for HIGM patient data collected from October 1992 to July 2015. Data fields included demographics, criteria for diagnosis, pedigree analysis, mutations, clinical features, treatment and transplant records, laboratory findings, and mortality...
July 2016: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/26793412/granulomatosis-with-polyangiitis-a-case-of-nasal-mass-necrotic-lung-and-normal-kidneys
#9
Ittikorn Spanuchart, Nath Zungsontiporn, Pichaya O-charoen, Bhisit Changcharoen, Dennis T Bolger
A diagnosis of granulomatosis with polyangiitis (GPA) can be challenging given various clinical manifestations. We report an incident case of GPA presenting with chronic sinusitis and mimicking an early lung abscess without renal involvement. A 51 year-old woman with chronic obstructive sinusitis presented with subacute dyspnea, pleuritic chest pain and fever. Physical examination revealed a right nasal mass without discharge or bleeding. Decreased to absent breath sounds and dullness to percussion were noted at the left lung base...
September 2015: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/26738743/carcinogenesis-of-nasopharyngeal-carcinoma-an-alternate-hypothetical-mechanism
#10
Sharon Shuxian Poh, Melvin Lee Kiang Chua, Joseph T S Wee
Current proposed mechanisms implicate both early and latent Epstein-Barr virus (EBV) infection in the carcinogenic cascade, whereas epidemiological studies have always associated nasopharyngeal carcinoma (NPC) with early childhood EBV infection and with chronic ear, nose, and sinus conditions. Moreover, most patients with NPC present with IgA antibody titers to EBV capsid antigen (VCA-IgA), which can precede actual tumor presentation by several years. If early childhood EBV infection indeed constitutes a key event in NPC carcinogenesis, one would have to explain the inability to detect the virus in normal nasopharyngeal epithelium of patients at a high risk for EBV infection...
2016: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/26678532/fighting-sinus-derived-staphylococcus-aureus-biofilms-in-vitro-with-a-bacteriophage-derived-muralytic-enzyme
#11
Amanda J Drilling, Clare Cooksley, Chun Chan, Peter-John Wormald, Sarah Vreugde
BACKGROUND: Staphylococcus aureus biofilms are a nidus for exacerbation of infectious conditions including chronic rhinosinusitis (CRS). Resistance of biofilms to current therapeutics stresses the need for the development of novel anti-biofilm strategies. The chimeric muralytic enzyme P128 was specifically engineered to target Staphylococcal sp. by combining the cell wall binding domain of lysostaphin and the peptidoglycan-degrading murein hydrolase derived from phage K. This study assessed the anti-biofilm activity of P128 against sinus-derived S...
April 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/26623567/evaluation-of-vitamin-d-levels-in-allergic-fungal-sinusitis-chronic-rhinosinusitis-and-chronic-rhinosinusitis-with-polyposis
#12
Badr El-Din Mostafa, Mohammed Shehata Taha, Tarek Abdel Hamid, Azza Omran, Neema Lotfi
BACKGROUND: Vitamin D3 (VD3 ) levels have been recently found to be responsible for a number of immunological, anti-inflammatory and anti-infectious roles. Some studies reported that some forms of allergic fungal rhinosinusitis (AFRS), occurs more commonly in patients who are more susceptible to VD3 deficiency. The aim of this work was to measure VD3 levels in patients with AFRS and chronic rhinosinusitis (CRS). METHODS: We report a prospective case control study conducted at Ain Shams University...
February 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/26488532/chronic-nasal-dysfunction-in-children-allergic-rhinitis-infectious-what-to-do-if-neither
#13
REVIEW
Julie L Wei
PURPOSE OF REVIEW: To review challenges in the diagnosis, work-up, and management of healthy children who present to the otolaryngologist with nasal dysfunction. Common symptoms include chronic nasal congestion, with or without rhinorrhea, with or without previous empirically treated 'allergic rhinitis' and/or 'sinus' infection. Symptoms are often unresolved despite chronic use of intranasal steroid, antihistamine, and/or leukotriene receptor antagonists. RECENT FINDINGS: There are no published studies addressing nasal symptoms in children who test negative for allergies yet report persistent nasal obstruction, congestion, and/or rhinorrhea...
December 2015: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/26148205/chronic-active-epstein-barr-virus-infection-with-cutaneous-and-sinus-lymphoproliferation-in-a-white-female-patient-with-25%C3%A2-years-follow-up-an-original-case-report
#14
C Picard, S Gouarin, F Comoz, M Barreau, L Verneuil, X Troussard, A Dompmartin
Chronic active Epstein-Barr virus infection (CAEBV) is characterized by chronic infectious mononucleosis-like symptoms associated with very high viral load, as assessed by quantitative polymerase chain reaction. We present an unusual case in a French woman who was followed up over 25 years with cutaneous and sinus lymphoproliferation. This white woman presented with a long history of recurrent cutaneous necrotic papules of the skin, which started during childhood and healed spontaneously with depressed scars...
November 2015: British Journal of Dermatology
https://www.readbyqxmd.com/read/26092582/immunoglobulin-g4-related-diseases-in-the-head-and-neck-a-systematic-review
#15
REVIEW
Graeme B Mulholland, Caroline C Jeffery, Paras Satija, David W J Côté
BACKGROUND: Immunoglobulin G4 related disease (IgG4-RD) is a poorly understood chronic inflammatory disorder affecting the middle-aged and elderly that can present to the otolaryngologist. We aim to summarize the current literature regarding the manifestations and management of IgG4-RD in the head and neck. METHODS: Pubmed and EMBASE were searched using the term relevant search algorithm utilizing keywords such as: IgG4 related disease, head and neck, orbit, salivary glands, sialadenitis, Kuttner, angiocentric eosinophilic fibrosis, submandibular, lacrimal, thyroid, dacryoadenitis, nasal, sinus, and Mikulicz's...
2015: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/26016054/a-curious-case-of-yellow-nail-syndrome
#16
Radu Crişan-Dabija, Traian Mihăescu
The Yellow Nail Syndrome is a rare clinical entity, first described in 1967 by P.D. Samman and W.F. White. The triad slow-growing dystrophic yellow nails, lymphedema and chronic respiratory disorders is the typical manifestation of the disease but some variations have been described as well as associations with chylothorax, chylous ascites, intestinal lymphangiectasia, thyroid abnormalities, malignancies and immunoglobulin A (IgA) deficiency. We present a case of a 55-years-old woman that had an insidious onset of respiratory disorders and chronic sinusitis, suspected to be infectious throughout the hospitalizations, associated with therapeutically neglected autoimmune thyroiditis...
January 2015: Pneumologia: Revista Societății Române de Pneumologie
https://www.readbyqxmd.com/read/26004175/nationwide-surveillance-of-6-otorhinolaryngological-infectious-diseases-and-antimicrobial-susceptibility-pattern-in-the-isolated-pathogens-in-japan
#17
Kenji Suzuki, Yuichi Kurono, Katsuhisa Ikeda, Akira Watanabe, Aikichi Iwamoto, Kyoichi Totsuka, Mitsuo Kaku, Satoshi Iwata, Jun-ichi Kadota, Hideaki Hanaki
The Japanese Three Academic Societies Joint Antimicrobial Susceptibility Surveillance Committee has conducted a nationwide surveillance on antimicrobial susceptibility patterns and rates of isolation in 6 otolaryngological diseases. The surveillance program was conducted in the otorhinolaryngological departments of 29 universities, and their 26 affiliated hospitals. Patients suffering from acute otitis media, chronic otitis media, acute nasal sinusitis, chronic nasal sinusitis, acute tonsillitis, and peritonsillar abscess between January 2011 and June 2012 were investigated...
July 2015: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/25890929/paraneoplastic-brainstem-encephalomyelitis-and-atypical-form-of-chronic-inflammatory-demyelinating-polyneuropathy-in-patient-with-testicular-germinal-tumor-is-this-an-overlap-syndrome-a-case-report
#18
Paweł Gogol, Anna Gogol, Andrzej Opuchlik, Dorota Dziewulska
Paraneoplastic neurologic syndromes are diagnosed when neurologic symptoms are associated with neoplasm and other causative factors are excluded. They may precede or be simultaneous to various types of neoplasms, mainly malignant. In men up to 45-50 years old the most common cancer causing the paraneoplastic syndrome is testicle tumor, manifesting usually as limbic/brain stem encephalitis and myelitis. Usually effective treatment of underlying neoplasm brings resolution of neurologic symptoms. But corticosteroids and intravenuous immunoglobulins are also used...
2015: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/25874470/-plastic-reconstructive-options-for-chronic-pilonidal-disease
#19
REVIEW
B Behr, A Ring, J Kolbenschlag, H-G Damert, M Lehnhardt, A Daigeler
INTRODUCTION: Chronic pilonidal disease represents an infectious disease of the gluteal cleft that often requires surgical resection. AIM: In this article, several plastic-surgical reconstructions are presented. METHODS AND RESULTS: Based on our experience and the current literature, different plastic surgical reconstructive methods are presented and discussed. Thorough debridement including sinus tracts and follicles represents an important step in the treatment algorithm...
April 2015: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/25774265/outcome-of-allogeneic-hematopoietic-stem-cell-transplantation-in-patients-with-hematological-malignancies
#20
Mohammad Faizan Zahid, Natasha Ali, Mohammad Usman Shaikh, Salman Naseem Adil
INTRODUCTION: Allogeneic hematopoietic stem cell transplantation is a potentially curative treatment modality for hematological malignancies. We evaluated the outcome of patients suffering from hematological malignancies, including acute leukemias, chronic myeloid leukemia and myelodysplastic syndrome after allogeneic transplantation. METHODS: All patients having hematological malignancies with HLA identical sibling donors who underwent allogeneic transplantation were included...
October 1, 2014: International Journal of Hematology-oncology and Stem Cell Research
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