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https://www.readbyqxmd.com/read/28335579/application-of-a-mems-based-trng-in-a-chaotic-stream-cipher
#1
Miguel Garcia-Bosque, Adrián Pérez, Carlos Sánchez-Azqueta, Santiago Celma
In this work, we used a sensor-based True Random Number Generator in order to generate keys for a stream cipher based on a recently published hybrid algorithm mixing Skew Tent Map and a Linear Feedback Shift Register. The stream cipher was implemented and tested in a Field Programmable Gate Array (FPGA) and was able to generate 8-bit width data streams at a clock frequency of 134 MHz, which is fast enough for Gigabit Ethernet applications. An exhaustive cryptanalysis was completed, allowing us to conclude that the system is secure...
March 21, 2017: Sensors
https://www.readbyqxmd.com/read/28335260/a-label-free-microelectrode-array-based-on-one-step-synthesis-of-chitosan-multi-walled-carbon-nanotube-thionine-for-ultrasensitive-detection-of-carcinoembryonic-antigen
#2
Huiren Xu, Yang Wang, Li Wang, Yilin Song, Jinping Luo, Xinxia Cai
Carcinoembryonic antigen (CEA) has been an extensively used tumor marker responsible for clinical early diagnosis of cervical carcinomas, and pancreatic, colorectal, gastric and lung cancer. Combined with micro-electro mechanical system (MEMS) technology, it is important to develop a novel immune microelectrode array (MEA) not only for rapid analysis of serum samples, but also for cell detection in vitro and in vivo. In this work, we depict a simple approach to modify chitosan-multi-walled carbon nanotubes-thionine (CS-MWCNTs-THI) hybrid film through one-step electrochemical deposition and the CS-MWCNTs-THI hybrid films are successfully employed to immobilize anti-CEA for fabricating simple, label-free, and highly sensitive electro-chemical immune MEAs...
July 11, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334787/the-development-and-validation-of-novel-simple-high-performance-liquid-chromatographic-method-with-refractive-index-detector-for-quantification-of-memantine-hydrochloride-in-dissolution-samples
#3
Tukaram B Sawant, Vikas S Wakchaure, Udyakumar K Rakibe, Prashant B Musmade, Bhata R Chaudhari, Dhananjay V Mane
The present study was aimed to develop an analytical method for quantification of memantine (MEM) hydrochloride in dissolution samples using high-performance liquid chromatography with refractive index (RI) detector. The chromatographic separation was achieved on C18 (250 × 4.5 mm, 5 μm) column using isocratic mobile phase comprises of buffer (pH 5.2):methanol (40:60 v/v) pumped at a flow rate of 1.0 mL/min. The column effluents were monitored using RI detector. The retention time of MEM was found to be ~6...
March 4, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28333587/variational-latent-gaussian-process-for-recovering-single-trial-dynamics-from-population-spike-trains
#4
Yuan Zhao, Il Memming Park
When governed by underlying low-dimensional dynamics, the interdependence of simultaneously recorded populations of neurons can be explained by a small number of shared factors, or a low-dimensional trajectory. Recovering these latent trajectories, particularly from single-trial population recordings, may help us understand the dynamics that drive neural computation. However, due to the biophysical constraints and noise in the spike trains, inferring trajectories from data is a challenging statistical problem in general...
March 23, 2017: Neural Computation
https://www.readbyqxmd.com/read/28333312/establishment-maintenance-and-functional-integrity-of-the-blood-testis-barrier-in-organotypic-cultures-of-fresh-and-frozen-thawed-prepubertal-mouse-testes
#5
C Rondanino, A Maouche, L Dumont, A Oblette, N Rives
STUDY QUESTION: Can the spatio-temporal formation of an intact blood-testis barrier (BTB), which is essential for the progression of spermatogenesis, be reproduced in cultures of fresh or frozen/thawed prepubertal mouse testes? SUMMARY ANSWER: Organotypic cultures allow the establishment and maintenance of major BTB components and the formation of a functional BTB in mouse testicular tissues. WHAT IS KNOWN ALREADY: In vitro maturation of prepubertal testicular tissues is a promising approach to restore fertility in adult survivors of childhood cancer...
March 17, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28332837/molecular-recognition-based-dna-nanoassemblies-on-the-surfaces-of-nanosized-exosomes
#6
Shuo Wan, Liqin Zhang, Sai Wang, Yuan Liu, Cuichen Wu, Cheng Cui, Hao Sun, Muling Shi, Ying Jiang, Long Li, Liping Qiu, Weihong Tan
Exosomes are membrane-enclosed extracellular vesicles derived from cells, carrying biomolecules that include pro-teins and nucleic acids for intercellular communication. Owning to their advantages of size, structure, stability and biocompatibility, exosomes have been used widely as natu-ral nanocarriers for intracellular delivery of theranostic agents. Meanwhile, surface modifications needed to endow exosomes with additional functionalities remain challeng-ing by their small size and the complexity of their mem-brane surfaces...
March 23, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28332815/detecting-subtle-vibrations-using-graphene-based-cellular-elastomers
#7
M Bulut Coskun, Ling Qiu, Md Shamsul Arefin, Adrian Neild, Mehmet Yuce, Dan Li, Tuncay Alan
Ultralight graphene elastomer-based flexible sensors are developed to detect subtle vibrations within a broad frequency range. The same device can be employed as an accelerometer, tested within the experimental bandwidth of 20-300 Hz as well as a microphone, monitoring sound pressures from 300 to 20 000 Hz. The sensing element does not contain any metal parts, making them undetectable by external sources and can provide an acceleration sensitivity of 2.6 mV/g, which is higher than or comparable to those of rigid Si-based piezoresistive microelectromechanical systems (MEMS)...
March 23, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28320724/piperacillin-tazobactam-versus-other-antibacterial-agents-for-treatment-of-bloodstream-infections-due-to-ampc-beta-lactamase-producing-enterobacteriaceae
#8
Lucy Cheng, Brian C Nelson, Monica Mehta, Nikhil Seval, Sarah Park, Marla J Giddins, Qiuhu Shi, Susan Whittier, Angela Gomez-Simmonds, Anne-Catrin Uhlemann
In vivo induction of AmpC beta-lactamases produces high-level resistance to many beta-lactam antibiotics in Enterobacteriaceae, often resulting in the use of carbapenems or cefepime (FEP). The clinical effectiveness of piperacillin-tazobactam (TZP), a weak inducer of AmpC beta-lactamases, is poorly understood. Here we conducted a case-control study of adult inpatients with bloodstream infections (BSIs) due to Enterobacter, Serratia, or Citrobacter spp. from 2009 to 2015 to assess outcomes following treatment with TZP compared to FEP or meropenem (MEM)...
March 20, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28317360/-construction-of-epithelial-membrane-protein-1-eukaryotic-expression-vector-and-its-influence-on-migration-and-invasion-of-human-oral-tongue-squamous-carcinoma-cells
#9
Dai Xiaohua, Zhang Jun, Zou Huiru, Lian Xiaoli, Li Yanni, Wang Guanhua, Yan Yan
OBJECTIVE: This study aimed to construct a eukaryotic expression vector pEGFP-N1-EMP1 of epithelial mem-brane protein 1 (EMP1) and investigate its influence on migration and invasion of human oral tongue squamous carcinoma cells. METHODS: The human EMP1 gene was amplified by reverse transcription polymerase chain reaction and then ligated into the pEGFP-N1 vector by double restriction endonuclease digestion to construct pEGFP-N1-EMP1 recombinant plasmid. After sequencing identification, pEGFP-N1-EMP1 recombinant plasmid and pEGFP-N1 plasmid were transfected into human oral tongue squamous carcinoma Tb3...
August 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28316089/optimal-mems-device-for-mobility-and-zeta-potential-measurements-using-dc-electrophoresis
#10
Pascal Karam, Andrei Dukhin, Sumita Pennathur
We have developed a novel microchannel geometry that allows us to perform simple DC electrophoresis to measure the electrophoretic mobility and zeta potential of analytes and particles. In standard capillary geometries, mobility measurements using DC fields are difficult to perform. Specifically, measurements in open capillaries require knowledge of the hard to measure and often dynamic wall surface potential. Although measurements in closed capillaries eliminate this requirement, the measurements must be performed at infinitesimally small regions of zero flow where the pressure driven-flow completely cancels the electroosmotic flow (Komagata Planes)...
March 18, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28303411/identifying-the-origin-of-effects-of-contralateral-noise-on-transient-evoked-otoacoustic-emissions-in-unanesthetized-mice
#11
Yingyue Xu, Mary Ann Cheatham, Jonathan H Siegel
Descending neural pathways in the mammalian auditory system are known to modulate the function of the peripheral auditory system. These pathways include the medial olivocochlear (MOC) efferent innervation to outer hair cells (OHCs) and the acoustic reflex pathways mediating middle ear muscle (MEM) contractions. Based on measurements in humans (Marks and Siegel, companion paper), we applied a sensitive method to attempt to differentiate MEM and MOC reflexes using contralateral acoustic stimulation in mice under different levels of anesthesia...
March 16, 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/28303246/cytotoxicity-and-antimicrobial-effects-of-a-new-fast-set-mta
#12
Michelle Shin, Jung-Wei Chen, Chi-Yang Tsai, Raydolfo Aprecio, Wu Zhang, Ji Min Yochim, Naichia Teng, Mahmoud Torabinejad
Purpose. To compare the biocompatibility and antimicrobial effectiveness of the new Fast-Set MTA (FS-MTA) with ProRoot MTA (RS-MTA). Methods. The agar overlay method with neutral red dye was used. L929 mouse fibroblast cells were cultured. The liquid and oil extracts and solid test material were placed on the agar overlay, four samples for each material. Phenol was used as the positive control and cottonseed oil and MEM extracts were used as negative controls. Cytotoxicity was examined by measuring the zones of decolorization and evaluating cell lysis under an inverted microscope using the established criteria after 24 and 48 hours...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28300526/effects-of-bone-morphogenetic-protein-4-bmp4-on-in-vitro-development-and-survival-of-bovine-preantral-follicles-enclosed-in-fragments-ovarian-tissue
#13
Ellen de Vasconcelos da Cunha, Glaucinete Borges de Souza, José Renato de Sousa Passos, Anderson Weiny Barbalho Silva, Andressa Minussi Dau, Márcia Viviane Alves Saraiva, Raimundo Nonato Braga Lobo, José Roberto Viana Silva
The aim of this study was to evaluate the effects of different concentrations of BMP4 on activation, development and mRNA expression of GDF9, BMP15, PCNA, Bax and Bcl2 in cultured bovine follicles enclosed in ovarian tissues. Ovarian tissue fragments were cultured for 6 days in α-MEM+ alone or supplemented with different concentrations of BMP4 (10, 50 or 100 ng/ml). Classical histology was performed to analyze follicle growth and morphology, while real-time PCR was used to analyze mRNA levels in fresh and cultured tissues...
March 16, 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28296643/hed-tie-a-wafer-scale-approach-for-fabricating-hybrid-electronic-devices-with-trench-isolated-electrodes
#14
Sreetama Banerjee, Daniel Bülz, Dmytro Solonenko, Danny Reuter, Carsten Deibel, Karla Hiller, Dietrich Zahn, Georgeta Salvan
Organic-inorganic hybrid electronic devices (HEDs) offer opportunities for functionalities that are not easily obtainable with either organic or inorganic materials individually. In the strive for down-scaling the channel length in planar geometry HEDs the records were achieved with electron beam lithography or nanoimprint lithography. Their application on the wafer level is, however, cost intensive and time consuming. Here, we propose the trench isolated electrodes (TIE) technology as a fast, cost effective, wafer level approach for fabrication of planar HEDs with electrode gaps in the range of 100 nm...
March 15, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28295692/addressable-and-color-tunable-piezophotonic-light-emitting-stripes
#15
Yan Chen, Yang Zhang, Daniil Karnaushenko, Li Chen, Jianhua Hao, Fei Ding, Oliver G Schmidt
Piezophotonic light-emitting devices have great potential for future microelectromechanical systems (MEMS) and nanoelectromechanical systems (NEMS) due to the added functionality provided by the electromechanical transduction coupled with the ability of light emission. Piezophotonic light-emitting source based on Pb(Mg1/3 Nb2/3 )O3 -PbTiO3 (PMN-PT) bulk is severely restricted by many challenges, such as high voltage burden, low integration density, and micromanufacturing complexity. Developing chip-integrated devices or incorporating such photonic components onto a Si platform is highly sought after in this field...
March 15, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28287483/mems-and-fog-technologies-for-tactical-and-navigation-grade-inertial-sensors-recent-improvements-and-comparison
#16
Olaf Deppe, Georg Dorner, Stefan König, Tim Martin, Sven Voigt, Steffen Zimmermann
In the following paper, we present an industry perspective of inertial sensors for navigation purposes driven by applications and customer needs. Microelectromechanical system (MEMS) inertial sensors have revolutionized consumer, automotive, and industrial applications and they have started to fulfill the high end tactical grade performance requirements of hybrid navigation systems on a series production scale. The Fiber Optic Gyroscope (FOG) technology, on the other hand, is further pushed into the near navigation grade performance region and beyond...
March 11, 2017: Sensors
https://www.readbyqxmd.com/read/28276745/predicting-adherence-to-combination-antiretroviral-therapy-for-hiv-in-tanzania-a-test-of-an-extended-theory-of-planned-behaviour-model
#17
Kasia Banas, Ramsey A Lyimo, Harm J Hospers, Andre van der Ven, Marijn de Bruin
OBJECTIVES: Combination antiretroviral therapy (cART) for HIV is widely available in sub-Saharan Africa. Adherence is crucial to successful treatment. This study aimed to apply an extended theory of planned behaviour (TPB) model to predict objectively measured adherence to cART in Tanzania. DESIGN: Prospective observational study (n = 158) where patients completed questionnaires on demographics (Month 0), socio-cognitive variables including intentions (Month 1), and action planning and self-regulatory processes hypothesised to mediate the intention-behaviour relationship (Month 3), to predict adherence (Month 5)...
February 13, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28273880/5-v-compatible-two-axis-pzt-driven-mems-scanning-mirror-with-mechanical-leverage-structure-for-miniature-lidar-application
#18
Liangchen Ye, Gaofei Zhang, Zheng You
The MEMS (Micro-Electronical Mechanical System) scanning mirror is an optical MEMS device that can scan laser beams across one or two dimensions. MEMS scanning mirrors can be applied in a variety of applications, such as laser display, bio-medical imaging and Light Detection and Ranging (LiDAR). These commercial applications have recently created a great demand for low-driving-voltage and low-power MEMS mirrors. However, no reported two-axis MEMS scanning mirror is available for usage in a universal supplying voltage such as 5 V...
March 5, 2017: Sensors
https://www.readbyqxmd.com/read/28273047/sensing-of-single-electrons-using-micro-and-nano-technologies-a-review
#19
Jubayer Jalil, Yong Zhu, Chandima Ekanayake, Yong Ruan
During the last three decades, the remarkable dynamic features of microelectromechanical systems (MEMS) and nanoelectromechanical systems (NEMS), and advances in solid-state electronics hold much potential for the fabrication of extremely sensitive charge sensors. These sensors have a broad range of applications, such as those involving the measurement of ionization radiation, detection of bio-analyte and aerosol particles, mass spectrometry, scanning tunneling microscopy, and quantum computation. Designing charge sensors (also known as charge electrometers) for electrometry is deemed significant because of the sensitivity and resolution issues in the range of micro- and nano-scales...
April 7, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28272330/design-and-optimization-of-a-stationary-electrode-in-a-vertically-driven-mems-inertial-switch-for-extending-contact-duration
#20
Qiu Xu, Zhuo-Qing Yang, Bo Fu, Yan-Ping Bao, Hao Wu, Yun-Na Sun, Meng-Yuan Zhao, Jian Li, Gui-Fu Ding, Xiao-Lin Zhao
A novel micro-electro-mechanical systems (MEMS) inertial microswitch with a flexible contact-enhanced structure to extend the contact duration has been proposed in the present work. In order to investigate the stiffness k of the stationary electrodes, the stationary electrodes with different shapes, thickness h, width b, and length l were designed, analyzed, and simulated using ANSYS software. Both the analytical and the simulated results indicate that the stiffness k increases with thickness h and width b, while decreasing with an increase of length l, and it is related to the shape...
March 7, 2017: Sensors
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