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https://www.readbyqxmd.com/read/28937916/nanoparticles-for-advanced-photodynamic-therapy-of-cancer
#1
Heidi Abrahamse, Cherie Ann Kruger, Sania Kadanyo, Ajay Mishra
The world widespread rise in cancer incidence has caused an increase in the demand for effective and safe materials for treatment. One of the most prevalent forms of treatment for cancer is photodynamic therapy (PDT), which is seen as an alternative to radiotherapy, as well as chemotherapy. In more recent years, researchers are exploring new nanotechnology-based strategies to improve the effectiveness of PDT. OBJECTIVE: The objective of this review is to explore the current trends and research findings associated with PDT and the development of nanotechnology as treatment modality for cancer...
September 21, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28937751/high-precision-simultaneous-18-o-16-o-13-c-12-c-and-17-o-16-o-analyses-for-%C3%A2%C2%B5g-quantities-of-caco3-by-tunable-infrared-laser-absorption-spectroscopy
#2
Saburo Sakai, Shinichi Matsuda, Toshihide Hikida, Akio Shimono, Barry J McManus, Mark S Zahniser, David D Nelson, David Dettman, Danzhou Yang, Naohiko Ohkouchi
Stable isotope ratios ((18)O/(16)O, (13)C/(12)C and (17)O/(16)O) in carbonates have contributed greatly to understanding of Earth and planetary systems, climates, and history. Current methods for measuring isotopologues of CO2 derived from CaCO3 are primarily gas-source isotope ratio mass spectroscopy (IRMS). However, IRMS has drawbacks, such as mass overlap by multiple CO2 isotopologues and contaminants, the requirement of careful sample purification, and use of major instrumentation needing permanent installation and a high power electrical supply...
September 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28937748/bio-optics-and-bio-inspired-optical-materials
#3
Sirimuvva Tadepalli, Joseph M Slocik, Maneesh K Gupta, Rajesh R Naik, Srikanth Singamaneni
Through the use of the limited materials palette, optimally designed micro- and nanostructures, and tightly regulated processes, nature demonstrates exquisite control of light-matter interactions at various length scales. In fact, control of light-matter interactions is an important element in the evolutionary arms race and has led to highly engineered optical materials and systems. In this review, we present a detailed summary of various optical effects found in nature with a particular emphasis on the materials and optical design aspects responsible for their optical functionality...
September 22, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28937646/effects-of-liposomes-contained-in-thermosensitive-hydrogels-as-biomaterials-useful-in-neural-tissue-engineering
#4
Yusser Olguín, Cristian Campos, Javiera Catalán, Luís Velásquez, Fernando Osorio, Iván Montenegro, Alejandro Madrid, Cristian Acevedo
Advances in the generation of suitable thermosensitive hydrogels for the delivery of cells in neural tissue engineering demonstrate a delicate relationship between physical properties and capabilities to promote cell proliferation and differentiation. To improve the properties of these materials, it is possible to add liposomes for the controlled release of bioactive elements, which in turn can affect the physical and biological properties of the hydrogels. In the present investigation, different hydrogels based on Pluronic F127 have been formulated with the incorporation of chitosan and two types of liposomes of two different sizes...
September 22, 2017: Materials
https://www.readbyqxmd.com/read/28937212/tunable-electrochemistry-via-controlling-lattice-water-in-layered-oxides-of-sodium-ion-batteries
#5
Kai Zhu, Shaohua Guo, Qi Li, Yingjin Wei, Gang Chen, Haoshen Zhou
Layered oxides based on abundant elements have been extensively studied as cathodes of sodium-ion batteries. Among them, Birnessite-type sodium manganese oxide containing lattice water meets the low-cost and high-performance requirement for stationary batteries. Herein, we for the first time present the controllable states of lattice water via adjusting the cut-off voltages, effectively enhancing the reversible capacity, cycling stability and rate ability of the materials. The current investigation not only highlights the significance of intercalated lattice water for reversible Na-(de)insertion of Birnessite as well as other similar compounds, but also opens up new opportunities for advanced cathode materials for sodium storage...
September 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28936647/3d-imaging-of-whole-mount-ovules-at-cellular-resolution-to-study-female-germline-development-in-rice
#6
Ethel Mendocilla-Sato, Wenjing She, Célia Baroux
Recent advances in fluorescence-based staining of cellular compartments coupled with confocal microscopy imaging have allowed the visualization of three-dimensional (3D) structures with cellular resolution in various intact plant tissues and species. Such approaches are of particular interest for the analysis of the reproductive lineage in plants including the meiotic precursor cells deeply embedded within the ovary of the gynoecium enclosed in the flower. Yet, their relative inaccessibility and the lack of optical clarity of plant tissues prevent robust staining and imaging across several cell layers...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28936500/confined-naalh4-nanoparticles-inside-ceo2-hollow-nanotubes-towards-enhanced-hydrogen-storage
#7
Qili Gao, Guanglin Xia, Xuebin Yu
NaAlH4 has been widely regarded as a potential hydrogen storage material due to its favorable thermodynamics and high energy density. The high activation energy barrier and high dehydrogenation temperature, however, significantly hinder its practical application. In this paper, CeO2 hollow nanotubes (HNTs) prepared by a simple electrospinning technique are adopted as functional scaffolds to support NaAlH4 nanoparticles (NPs) towards advanced hydrogen storage performance. The nanoconfined NaAlH4 inside CeO2 HNTs, synthesized via the infiltration of molten NaAlH4 into the CeO2 HNTs under high hydrogen pressure, exhibited significantly improved dehydrogenation properties compared with both bulk and ball-milled CeO2 HNTs-catalyzed NaAlH4...
September 22, 2017: Nanoscale
https://www.readbyqxmd.com/read/28935259/module-based-systematic-construction-of-plasmids-for-episomal-gene-expression-in-fission-yeast
#8
Keita Kiriya, Hayato Tsuyuzaki, Masamitsu Sato
The fission yeast Schizosaccharomyces pombe is a powerful model organism for cell biology and molecular biology, as genetic manipulation is easily achieved. Introduction of exogenous genes cloned in episomal plasmids into yeast cells can be done through well-established transformation methods. For expression of genes in S. pombe cells, the multi-copy plasmid pREP1 and its derivatives, including pREP41 and pREP81, have been widely used as vectors. Although recent advancement of technology brought a number of useful genetic elements such as new promoters, selection marker genes and fluorescent protein tags, introduction of those elements into conventional pREP1 requires a large commitment of both time and effort because cloning procedures need to be repeated until the final products are constructed...
September 18, 2017: Gene
https://www.readbyqxmd.com/read/28934899/knowledge-about-and-attitude-towards-fertility-preservation-in-young-female-cancer-patients-a-cross-sectional-online-survey
#9
Corinne Urech, Verena Ehrbar, Jacky Boivin, Madleina Müller, Judith Alder, Rosanna Zanetti Dällenbach, Christoph Rochlitz, Sibil Tschudin
Recent advances in cancer therapy have resulted in an increased number of long-term cancer survivors. However, because of their treatment, women might be confronted with impaired fertility. The options of fertility preservation (FP) techniques are increasing. The goal of this study was to assess knowledge about, and attitudes towards, fertility preservation in young female cancer patients. A cross-sectional online survey was conducted including 155 former female cancer patients from English and German speaking countries...
September 22, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28934809/ct-and-mri-techniques-for-imaging-around-orthopedic-hardware
#10
Thuy Duong Do, Reto Sutter, Stephan Skornitzke, Marc-André Weber
Orthopedic hardware impairs image quality in cross-sectional imaging. With an increasing number of orthopedic implants in an aging population, the need to mitigate metal artifacts in computed tomography and magnetic resonance imaging is becoming increasingly relevant. This review provides an overview of the major artifacts in CT and MRI and state-of-the-art solutions to improve image quality. All steps of image acquisition from device selection, scan preparations and parameters to image post-processing influence the magnitude of metal artifacts...
September 21, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28934673/an-analysis-of-chemicals-and-other-constituents-found-in-produced-water-from-hydraulically-fractured-wells-in-california-and-the-challenges-for-wastewater-management
#11
Emily A Chittick, Tanja Srebotnjak
As high-volume hydraulic fracturing (HF) has grown substantially in the United States over the past decade, so has the volume of produced water (PW), i.e., briny water brought to the surface as a byproduct of oil and gas production. According to a recent study (Groundwater Protection Council, 2015), more than 21 billion barrels of PW were generated in 2012. In addition to being high in TDS, PW may contain hydrocarbons, PAH, alkylphenols, naturally occurring radioactive material (NORM), metals, and other organic and inorganic substances...
September 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28934176/positron-emission-tomographic-imaging-elucidates-the-complex-relationship-between-glucose-uptake-and-tissue-blood-flow-mechanism-in-squamous-cell-oral-cancer-patients
#12
Ping Xu, Yan Li, Shuyong Yang, Mingzhe Li, Chenjun Li
BACKGROUND Through the clinical use of positron emission tomography, we aimed to elucidate the complex relationship between glucose uptake and squamous cell oral cancer (ScOC) growth, along with its mechanism with respect to tissue blood flow (tBF). MATERIAL AND METHODS We retrospectively reviewed a total of 69 newly diagnosed ScOC patients by Fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET). Maximum and mean standard uptake values (SUV↑ and SUV) were recorded to assess glucose uptake...
September 21, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28934127/removal-of-phenolic-compounds-from-water-using-sewage-sludge-based-activated-carbon-adsorption-a-review
#13
REVIEW
Nuhu Dalhat Mu'azu, Nabeel Jarrah, Mukarram Zubair, Omar Alagha
Due to their industrial relevance, phenolic compounds (PC) are amongst the most common organic pollutants found in many industrial wastewater effluents. The potential detrimental health and environmental impacts of PC necessitate their removal from wastewater to meet regulatory discharge standards to ensure meeting sustainable development goals. In recent decades, one of the promising, cost-effective and environmentally benign techniques for removal of PC from water streams has been adsorption onto sewage sludge (SS)-based activated carbon (SBAC)...
September 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28933826/a-modern-twist-to-a-classic-synthetic-route-ph3bi-based-redox-transmetalation-protolysis-rtp-for-the-preparation-of-barium-metalorganic-species
#14
Yuriko Takahashi, Anna O'Brien, Glen B Deacon, Philip C Andrews, Melanie Wolf, Ana Torvisco, Miriam M Gillett-Kunnath, Karin Ruhlandt-Senge
This paper reports advances in redox transmetalation/protolysis (RTP) utilizing the readily available Ph3Bi for the synthesis of a series of barium metal-organic species. On the basis of easily available starting materials, an easy one-pot procedure, and workup, we have obtained BaL2 compounds (L = bis(trimethylsilyl)amide, phenyl(trimethylsilyl)amide, pentamethylcyclopentadienide, fluorenide, 2,6-di-isopropylphenolate, and 3,5-diphenylpyrazolate) quantitatively by sonication of an excess of barium metal with triphenylbismuth and HL in perdeuterotetrahydrofuran, as established by NMR measurements...
September 21, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28933464/highlights-from-the-faraday-discussion-on-new-directions-in-porous-crystalline-materials-edinburgh-uk-june-2017
#15
Matthew A Addicoat, Thomas D Bennett, Ivo Stassen
A lively discussion on new directions in porous crystalline materials took place in June 2017, with the beautiful city of Edinburgh as a backdrop, in the context of the unique Faraday Discussions format. Here, 5 minute presentations were given on papers which had been submitted in advance of the conference, with copious time allocated for in-depth discussion of the work presented. Prof. Mircea Dincă (MIT), chair of the scientific committee, opened the conference by welcoming the many different nationalities attending, and outlining the format of discussions...
September 21, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28933330/-short-term-results-of-surgical-treatment-of-patients-with-hallux-rigidus
#16
M Dygrýnová, M Uvízl, J Gallo
PURPOSE OF THE STUDY Hallux rigidus is common and degenerative arthritis of the first metatarsophalangeal joint. The aim of this study was to assess the results of cheilectomy and total joint replacement (TJR) in patients with hallux rigidus. Minimum duration of followup was 18 months. MATERIAL AND METHODS The study included fifty-nine patients who underwent surgery at our Department due to hallux rigidus between January 2013 and December 2014. Thirty-seven patients underwent cheilectomy and twenty-two patients had total joint arthroplasty using METIS®...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28933299/hydrogel-dressings-for-advanced-wound-management
#17
Antonio Francesko, Petya Petkova, Tzanko Tzanov
Composed in a large extent of water and due to their non-adhesiveness, hydrogels found their way to the wound dressing market as materials that provide a moisture environment for healing while being comfortable to the patient. Hydrogels' exploitation is constantly increasing after evidences of their even broader therapeutic potential due to resemblance to dermal tissue and ability to induce partial skin regeneration. The innovation in advanced wound care is further directed to the development of so-called active dressings, where hydrogels are combined with components that enhance the primary purpose of providing a beneficial environment for wound healing...
September 20, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28932928/a-phase-i-study-to-assess-the-mass-balance-excretion-and-pharmacokinetics-of-14-c-ixazomib-an-oral-proteasome-inhibitor-in-patients-with-advanced-solid-tumors
#18
Neeraj Gupta, Steven Zhang, Sandeepraj Pusalkar, Mihaela Plesescu, Swapan Chowdhury, Michael J Hanley, Bingxia Wang, Cindy Xia, Xiaoquan Zhang, Karthik Venkatakrishnan, Dale R Shepard
This two-part, phase I study evaluated the mass balance, excretion, pharmacokinetics (PK), and safety of ixazomib in patients with advanced solid tumors. In Part A of the study, patients received a single 4.1 mg oral solution dose of [(14)C]-ixazomib containing ~500 nCi total radioactivity (TRA), followed by non-radiolabeled ixazomib (4 mg capsule) on days 14 and 21 of the 35-day PK cycle. Patients were confined to the clinic for the first 168 h post dose and returned for 24 h overnight clinic visits on days 14, 21, 28, and 35...
September 21, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28932919/how-does-homelessness-affect-parenting-behaviour-a-systematic-critical-review-and-thematic-synthesis-of-qualitative-research
#19
REVIEW
Caroline Bradley, John McGowan, Daniel Michelson
The adverse social and physical conditions of homelessness pose significant developmental risks for children, which may be compounded or buffered by the quality of parenting behaviour they are exposed to. There is currently a limited understanding of how parents approach their care-giving role and responsibilities while adjusting to the experience of homelessness. Advancing knowledge in this area is essential for developing acceptable, appropriate and effective interventions to support highly marginalised and vulnerable homeless families...
September 20, 2017: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/28932664/strong-electro-optic-effect-and-spontaneous-domain-formation-in-self-assembled-peptide-structures
#20
Barak Gilboa, Clément Lafargue, Amir Handelman, Linda J W Shimon, Gil Rosenman, Joseph Zyss, Tal Ellenbogen
Short peptides made from repeating units of phenylalanine self-assemble into a remarkable variety of micro- and nanostructures including tubes, tapes, spheres, and fibrils. These bio-organic structures are found to possess striking mechanical, electrical, and optical properties, which are rarely seen in organic materials, and are therefore shown useful for diverse applications including regenerative medicine, targeted drug delivery, and biocompatible fluorescent probes. Consequently, finding new optical properties in these materials can significantly advance their practical use, for example, by allowing new ways to visualize, manipulate, and utilize them in new, in vivo, sensing applications...
September 2017: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
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