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https://www.readbyqxmd.com/read/28212648/formulation-of-evidence-based-messages-to-promote-the-use-of-physical-activity-to-prevent-and-manage-alzheimer-s-disease
#1
Kathleen A Martin Ginis, Jennifer Heisz, John C Spence, Ilana B Clark, Jordan Antflick, Chris I Ardern, Christa Costas-Bradstreet, Mary Duggan, Audrey L Hicks, Amy E Latimer-Cheung, Laura Middleton, Kirk Nylen, Donald H Paterson, Chelsea Pelletier, Michael A Rotondi
BACKGROUND: The impending public health impact of Alzheimer's disease is tremendous. Physical activity is a promising intervention for preventing and managing Alzheimer's disease. However, there is a lack of evidence-based public health messaging to support this position. This paper describes the application of the Appraisal of Guidelines Research and Evaluation II (AGREE-II) principles to formulate an evidence-based message to promote physical activity for the purposes of preventing and managing Alzheimer's disease...
February 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28212145/assessing-and-managing-acute-pain-a-call-to-action
#2
Carla R Jungquist, April Hazard Vallerand, Corinna Sicoutris, Kyung N Kwon, Rosemary C Polomano
: Acute pain, which is usually sudden in onset and time limited, serves a biological protective function, warning the body of impending danger. However, while acute pain often resolves over time with normal healing, unrelieved acute pain can disrupt activities of daily living and transition to chronic pain. This article describes the effects of unrelieved acute pain on patients and clinical outcomes. The authors call on nurses to assess and manage acute pain in accordance with evidence-based guidelines, expert consensus reports, and position statements from professional nursing organizations in order to minimize the likelihood of its becoming chronic...
March 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28210230/acute-mental-discomfort-associated-with-suicide-behavior-in-a-clinical-sample-of-patients-with-affective-disorders-ascertaining-critical-variables-using-artificial-intelligence-tools
#3
Susana Morales, Jorge Barros, Orietta Echávarri, Fabián García, Alex Osses, Claudia Moya, María Paz Maino, Ronit Fischman, Catalina Núñez, Tita Szmulewicz, Alemka Tomicic
AIM: In efforts to develop reliable methods to detect the likelihood of impending suicidal behaviors, we have proposed the following. OBJECTIVE: To gain a deeper understanding of the state of suicide risk by determining the combination of variables that distinguishes between groups with and without suicide risk. METHOD: A study involving 707 patients consulting for mental health issues in three health centers in Greater Santiago, Chile. Using 345 variables, an analysis was carried out with artificial intelligence tools, Cross Industry Standard Process for Data Mining processes, and decision tree techniques...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28209473/analysis-of-peripheral-t-cell-lymphoma-diagnostic-workup-in-the-united-states
#4
Eric D Hsi, Steven M Horwitz, Kenneth R Carson, Lauren C Pinter-Brown, Steven T Rosen, Barbara Pro, Massimo Federico, Christian Gisselbrecht, Marc Schwartz, Lisa A Bellm, Mark Acosta, Angela M Collie, Aaron M Gruver, Bartosz J Grzywacz, Samir Turakhia, Andrei R Shustov, Ranjana H Advani, Tatyana Feldman, Mary Jo Lechowicz, Sonali M Smith, Frederick Lansigan, Anil Tulpule, Michael D Craig, John P Greer, Brad S Kahl, Joseph W Leach, Neil Morganstein, Carla Casulo, Steven I Park, Francine M Foss
BACKGROUND: With increased understanding of the unique entities, subtype-specific approaches for peripheral T-cell lymphoma (PTCL) are emerging, and more precise diagnoses are becoming increasingly important. PATIENTS AND METHODS: We analyzed the approach to the histopathologic diagnosis of PTCL using data from the comprehensive oncology measures of peripheral T-cell lymphoma (COMPLETE) study. The COMPLETE trial is a large prospective cohort study of patients with newly diagnosed PTCL in the United States...
January 10, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28209144/modified-enhanced-recovery-after-surgery-eras-protocols-for-patients-with-obstructive-colorectal-cancer
#5
Dai Shida, Kyoko Tagawa, Kentaro Inada, Keiichi Nasu, Yasuji Seyama, Tsuyoshi Maeshiro, Sachio Miyamoto, Satoru Inoue, Nobutaka Umekita
BACKGROUND: Enhanced recovery after surgery (ERAS) protocols are now well-known to be useful for elective colorectal surgery, as they result in shorter hospital stays without adversely affecting morbidity. However, the efficacy and safety of ERAS protocols for patients with obstructive colorectal cancer have yet to be clarified. METHODS: We evaluated 122 consecutive resections for obstructive colorectal cancer performed between July 2008 and November 2012 at Tokyo Metropolitan Bokutoh Hospital...
February 16, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28207809/kazakhstan-can-achieve-ambitious-hiv-targets-despite-expected-donor-withdrawal-by-combining-improved-art-procurement-mechanisms-with-allocative-and-implementation-efficiencies
#6
Andrew J Shattock, Clemens Benedikt, Aliya Bokazhanova, Predrag Đurić, Irina Petrenko, Lolita Ganina, Sherrie L Kelly, Robyn M Stuart, Cliff C Kerr, Tatiana Vinichenko, Shufang Zhang, Christoph Hamelmann, Manoela Manova, Emiko Masaki, David P Wilson, Richard T Gray
BACKGROUND: Despite a non-decreasing HIV epidemic, international donors are soon expected to withdraw funding from Kazakhstan. Here we analyze how allocative, implementation, and technical efficiencies could strengthen the national HIV response under assumptions of future budget levels. METHODOLOGY: We used the Optima model to project future scenarios of the HIV epidemic in Kazakhstan that varied in future antiretroviral treatment unit costs and management expenditure-two areas identified for potential cost-reductions...
2017: PloS One
https://www.readbyqxmd.com/read/28196033/thromboembolic-disease-in-patients-with-metastatic-femoral-lesions-a-comparison-between-prophylactic-fixation-and-fracture-fixation
#7
Arun Aneja, Jimmy J Jiang, Anna Cohen-Rosenblum, Hue L Luu, Terrance D Peabody, Samer Attar, T David Luo, Rex C Haydon
BACKGROUND: We are not aware of any previous studies that have compared the rate of venous thromboembolic events in patients who underwent prophylactic intramedullary nailing because of an impending fracture with the rate in patients who underwent intramedullary nailing after a pathological fracture. The objective of the present study was to determine if the rate of venous thromboembolic events varies between patients who are managed with prophylactic fixation and those who are managed with fixation after a pathological fracture...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28190872/upper-airway-obstruction-requiring-emergent-tracheostomy-secondary-to-laryngeal-sarcoidosis-a-case-report
#8
Changwan Ryu, Erica L Herzog, Hongyi Pan, Robert Homer, Mridu Gulati
BACKGROUND Laryngeal sarcoidosis is a rare extrapulmonary manifestation of sarcoidosis, accounting for 0.33-2.1% of cases. A life-threatening complication of laryngeal sarcoidosis is upper airway obstruction. In this report we describe our experience in the acute and chronic care of a patient who required an emergent tracheostomy, with the aim to provide further insight into this difficult to manage disease. CASE REPORT A 37-year-old African American female with a 10-year history of stage 1 sarcoidosis presented with severe dyspnea...
February 13, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28190790/knowing-one-s-death-philosophical-considerations
#9
Siby K George
Coming to know and accept one's impending death allows terminally ill persons to face their mortality without deception. While life as such is a constant race towards death, terminal illness brings one's own death closer to experience. Being in the face of death in this manner can be transformed into an ontologically rewarding experience. Research on medical practices of truth telling in cases of terminal illness tends to show that there is healthy acceptance of impending death in western contexts, whereas in other contexts patients are more likely to do well when poor prognosis is concealed from them...
January 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28188956/the-neural-substrate-of-gait-and-executive-function-relationship-in-elderly-women-a-pet-study
#10
Ryota Sakurai, Kenji Ishii, Masashi Yasunaga, Rumi Takeuchi, Yoh Murayama, Naoko Sakuma, Muneyuki Sakata, Keiichi Oda, Kenji Ishibashi, Kiichi Ishiwata, Yoshinori Fujiwara, Manuel Montero-Odasso
AIM: Understanding the relationship between age-related gait impairment, such as slow gait, and executive functioning in seniors may help identify individuals at higher risk of mobility decline, falls, and progression to dementia at earlier stages. We aim to identify brain regions concomitantly associated with poor gait and executive functioning in a cohort of well-functioning elderly women. METHODS: In total, 149 well-functioning women aged 70.1 ± 6.2 years underwent FDG-PET to evaluate regional cerebral metabolic rates of glucose normalized in reference to cerebellar glucose metabolic value (normalized-rCMRglc) in 16 brain areas...
February 11, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28183325/percutaneous-internal-fixation-with-y-strut%C3%A2-device-to-prevent-both-osteoporotic-and-pathological-hip-fractures-a-prospective-pilot-study
#11
François H Cornelis, Lambros Tselikas, Thibault Carteret, Bruno Lapuyade, Thierry De Baere, Jean Charles Le Huec, Frédéric Deschamps
BACKGROUND: We studied Y-STRUT® (Hyprevention, France), a new percutaneous internal fixation device, in combination with bone cementoplasty to prevent hip fracture. METHODS: Between February 2013 and February 2015, a total of 16 femoral necks in 4 osteoporotic and 12 oncologic patients have been considered for prophylactic consolidation in this prospective multicentre pilot study involving 4 different hospitals. These consolidations were performed percutaneously under fluoroscopic guidance using Y-STRUT®, a dedicated internal fixation device...
February 9, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28182781/test-anxiety-in-medical-school-is-unrelated-to-academic-performance-but-correlates-with-an-effort-reward-imbalance
#12
Henry Hahn, Peter Kropp, Timo Kirschstein, Gernot Rücker, Brigitte Müller-Hilke
PURPOSE: During their early years at medical school, students repeatedly criticize their workload, time constraints and test associated stress. At the same time, depressiveness and anxiety among first and second year medical students are on the rise. We therefore hypothesized that test anxiety may be related to depressiveness and considered cognitive and academic performances as confounders for the former and psychosocial distress for the latter. METHODS: A whole class of 200 second year students was invited to participate in the study...
2017: PloS One
https://www.readbyqxmd.com/read/28169209/place-of-death-for-hospice-cared-terminal-patients-with-cancer-a-nationwide-retrospective-study-in-taiwan
#13
Heng-Yi Lin, Shih-Chao Kang, Yu-Chun Cheng, Yin-Chieh Chang, Wei-Shu Wang, Su-Shun Lo
BACKGROUND: Hospice care has been part of the Taiwan health-care system for 20 years. Detailed information on the place of death for terminal cancer patients is lacking. Impending death discharge (IDD) is unique in Taiwan, and our study aims to compare IDD with in-hospice death among terminal cancer patients under hospice care. METHODS: This retrospective study used claims data of decedents of cancer from the National Health Insurance Research Database of Taiwan from 2007 to 2010...
February 3, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28162788/pathways-of-impending-disease-flare-in-african-american-systemic-lupus-erythematosus-patients
#14
Melissa E Munroe, Evan S Vista, Joan T Merrill, Joel M Guthridge, Virginia C Roberts, Judith A James
Immune dysregulation in systemic lupus erythematosus (SLE) contributes to increased disease activity. African-American (AA) SLE patients have an increased prevalence of complications from disease flares and end-organ damage that leads to increased morbidity and early mortality. We previously reported alterations in inflammatory and regulatory immune mediator levels prior to disease flare in European American (EA) SLE patients. In the current study, we assessed baseline and follow-up plasma levels of 52 soluble mediators, including innate, adaptive, chemokine, and TNF superfamily members, in AA SLE patients who developed SELENA-SLEDAI defined flare 6 or 12 weeks after baseline assessment...
February 2, 2017: Journal of Autoimmunity
https://www.readbyqxmd.com/read/28159523/a-novel-automated-somatosensory-evoked-potential-ssep-monitoring-device-for-detection-of-intraoperative-peripheral-nerve-injury-in-cardiac-surgery-a-clinical-feasibility-study
#15
Jason Chui, John M Murkin, Timothy Turkstra, Neil McKenzie, Linrui Guo, Mackenzie Quantz
OBJECTIVE: Peripheral nerve injury (PNI) is a common and potentially devastating complication in cardiac surgery. Somatosensory evoked potential (SSEP) monitoring is one of the modalities for PNI; however, its application is limited by complicated logistics. This study aimed to assess the feasibility of using a novel, automated SSEP device (EPAD; SafeOp Surgical, Hunt Valley, MD) for detection of intraoperative PNI during cardiac surgery. DESIGN: Prospective, observational study...
November 17, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28154015/potential-ways-to-address-shortage-situations-of-mo-99-tc-99m
#16
Leah Filzen, Lacey Ellingson, Andrew Paulsen, Joseph Hung
: Technetium 99m (Tc-99m) is the most common radioisotope used in nuclear medicine, which is produced in a nuclear reactor from the decay of molybdenum-99 (Mo-99). There are only a few aging nuclear reactors around the world that produce Mo-99 and one of the major contributors, the NRU (National Research Universal, Canada), will cease production on October 31, 2016. The NRU produces approximately 40% of the world's Mo-99 supply, so with its impending shut down, shortages of Mo-99/Tc-99m are expected...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28149807/continuous-intraoperative-neural-monitoring-of-the-recurrent-nerves-in-thyroid-surgery-a-quantum-leap-in-technology
#17
REVIEW
Rick Schneider, Gregory W Randolph, Marcin Barczynski, Gianlorenzo Dionigi, Che-Wei Wu, Feng-Yu Chiang, Andreas Machens, Dipti Kamani, Henning Dralle
The continuous intraoperative neural monitoring (CIONM) technique is increasingly acknowledged as a useful tool to recognize impending nerve injury and to abort the related manoeuvre to prevent nerve injury during thyroid surgery. CIONM provides valuable real-time information constantly, which is really useful during complex thyroid surgeries especially in the settings of unusual anatomy. Thus, CIONM overcomes the key methodological limitation inherent in intermittent nerve monitoring (IINOM); which is allowing the nerve to be at risk in between the stimulations...
December 2016: Gland Surgery
https://www.readbyqxmd.com/read/28138372/ethnomedicinal-cichorium-intybus-seed-extracts-an-impending-preparation-against-multidrug-resistant-bacterial-pathogens
#18
Hazir Rahman, Usman Ali Khan, Muhammad Qasim, Noor Muhammad, Muhammad Daud Khan, Muhammad Asif, Azizullah Azizullah, Muhammad Adnan, Waheed Murad
BACKGROUND: The present study was undertaken to analyze the phytochemical content and biological activity of Cichorium intybus seeds traditionally used in Charsadda, Pakistan against multidrug resistant (MDR) bacterial pathogens. OBJECTIVES: This study explored the qualitative and quantitative antibacterial potential of C. intybus. Further qualitative analysis of phytochemical content was performed. METHODS: Cichorium intybus seed extracts were prepared in aqueous, chloroform, ethanol, and hexane separately...
November 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/28138360/serum-levels-of-undercarboxylated-osteocalcin-are-related-to-cardiovascular-risk-factors-in-patients-with-type-2-diabetes-mellitus-and-healthy-subjects
#19
Sergio Sanchez-Enriquez, Isabel Thalia Ballesteros-Gonzalez, José Rafael Villafán-Bernal, Sara Pascoe-Gonzalez, Edgar Alfonso Rivera-Leon, Blanca Estela Bastidas-Ramirez, Jorge David Rivas-Carrillo, Juan Luis Alcala-Zermeno, Juan Armendariz-Borunda, Iris Monserrat Llamas-Covarrubias, Abraham Zepeda-Moreno
AIM: To determine a potential relationship between serum undercarboxylated (ucOC) concentration and cardiovascular risk factors in type 2 diabetes (T2D) patients and healthy subjects (HS). METHODS: A cross-sectional study was conducted on 140 subjects classified into two groups, 70 with T2D and 70 HS. Medical history and physical examination with anthropometric measurements were obtained from all subjects. Body fat percentage was determined by bioelectrical impendency analysis...
January 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28125898/mechanisms-and-factors-associated-with-tackle-related-injuries-in-south-african-youth-rugby-union-players
#20
Nicholas Burger, Mike Ian Lambert, Wayne Viljoen, James Craig Brown, Clint Readhead, Steve den Hollander, Sharief Hendricks
BACKGROUND: The majority of injuries in rugby union occur during tackle events. The mechanisms and causes of these injuries are well established in senior rugby union. PURPOSE: To use information from an injury database and assess video footage of tackle-related injuries in youth rugby union matches to identify environmental factors and mechanisms that are potentially confounding to these injuries. STUDY DESIGN: Descriptive epidemiological study...
February 2017: American Journal of Sports Medicine
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