Read by QxMD icon Read


Andrea Droghetti, Alessandro Locatelli, Bruno Casiraghi, Maurizio Malacrida, Michele Arupi, Mark Ragusa
The subcutaneous implantable cardioverter-defibrillator (S-ICD) is a safe alternative to transvenous ICD. We describe a submuscular S-ICD placement technique in a severely obese with an oversized chest. Submuscular configuration allows optimal system positioning and impendence values warranting a safe and effective shock transmission. This technique is safe and improves patients comfort.
October 2016: Clinical Case Reports
Patrick J Buchanan, Robert H Gilman
Vitamin A-containing products have been used topically since the early 1940s to treat various skin conditions. To date, there are four generations of retinoids, a family of Vitamin A-containing compounds. Tretinoin, all-trans-retinoic acid, is a first-generation, naturally occurring, retinoid. It is available, commercially, as a gel or cream. The authors conducted a complete review of all studies, clinical- and basic science-based studies, within the literature involving tretinoin treatment recommendations for impending facial procedures...
July 2016: Journal of Cutaneous and Aesthetic Surgery
Giacomo Murana, Mariano Cefarelli, Geoffrey Kloppenburg, Wim J Morshuis, Robin H Heijmen
In adult the patent ductus arteriosus is a rare condition associated sometimes with lethal complications. We describe the case of a 44-year-old woman with a history of systemic lupus erythematosus admitted to our hospital with hoarseness and severe dyspnea. Clinical imaging examinations indicated a saccular aneurysm within a persistent ductus arteriosus with signs of impending rupture. Patient was not considered suitable for transcatheter closure and therefore she underwent open aortic repair. The procedure was uneventful and any significant complications occurred during postoperative course...
October 19, 2016: Future Cardiology
Sheila M Gephart, Michelle Fleiner, Amy Kijewski
BACKGROUND: Necrotizing enterocolitis (NEC) can become severe quickly, making early recognition a priority and understanding the occurrence of abdominal and clinical signs of impending NEC important. PURPOSE: The purpose of this study was to examine relationships of abdominal signs up to 36 hours before diagnosis of NEC within subgroups treated medically, surgically, or those who died. METHODS: A 3-site, descriptive correlational case-control design with retrospective data collection was used matching each NEC case to 2 controls (N = 132)...
October 14, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Q M J van der Vliet, N R Paulino Pereira, S J Janssen, F J Hornicek, M L Ferrone, J A M Bramer, C N van Dijk, J H Schwab
BACKGROUND: It would be helpful for the decision-making process of patients with metastatic bone disease to understand which patients are at risk for worse quality of life (QOL), pain, anxiety, and depression. Normative data, and where these stand compared with general population scores, can be useful to compare and interpret results of similar patients or patient groups, but to our knowledge, there are no such robust data. QUESTIONS/PURPOSES: We wished (1) to assess what factors are independently associated with QOL, pain interference, anxiety, and depression in patients with metastatic bone disease, and (2) to compare these outcomes with general US population values...
October 17, 2016: Clinical Orthopaedics and related Research
Yoav Nahum, Irit Bahar, Massimo Busin
PURPOSE: To report the use of Descemet stripping automated endothelial keratoplasty (DSAEK) for treatment of sterile corneal perforations accompanying endothelial decompensation. METHODS: In this multicenter interventional case series, we reviewed the medical records of all tectonic DSAEK surgeries performed at Villa Serena-Villa Igea private Hospitals (Forlì, Italy) and Rabin Medical Center (Petach Tikva, Israel) between January 2014 and March 2016. RESULTS: Three patients with endothelial decompensation and sterile corneal perforation (n = 2) or impending corneal perforation (n = 1) underwent DSAEK between 2014 and 2015 at Villa Igea Hospital, Forlì, Italy, and Rabin Medical Center, Petach Tikva, Israel...
October 5, 2016: Cornea
Sushanto Gouda, Gitishree Das, Sandeep K Sen, Han-Seung Shin, Jayanta Kumar Patra
Endophytes are an endosymbiotic group of microorganisms that colonize in plants and microbes that can be readily isolated from any microbial or plant growth medium. They act as reservoirs of novel bioactive secondary metabolites, such as alkaloids, phenolic acids, quinones, steroids, saponins, tannins, and terpenoids that serve as a potential candidate for antimicrobial, anti-insect, anticancer and many more properties. While plant sources are being extensively explored for new chemical entities for therapeutic purposes, endophytic microbes also constitute an important source for drug discovery...
2016: Frontiers in Microbiology
Danica Železnik, Peter Kokol, Helena Blažun Vošner
BACKGROUND: New emerging technologies, health globalization, demographic change, new healthcare paradigms, advances in healthcare delivery and social networking will change the needs of patients in the future and consequently will require that new knowledge, competence and skill sets be acquired by nurses. METHOD: Checkland's Soft Systems Methodology, focusing on the enriched CATWOE and PQR elements of the root definitions, combined with our own developed "Too much - Too little constraint" approach was used to devise impending knowledge, competence and skill sets...
September 28, 2016: Nurse Education Today
Neil M Drummond, Alexandra Leguerrier, Anthony N Carlsen
During a simple reaction time (RT) task, movements can be initiated early and involuntarily through presentation of a loud startling acoustic stimulus (SAS), a phenomenon termed the StartReact effect. In order to infer that activity in startle-related structures led to the early response triggering, it is important to observe a concurrent startle reflex in sternocleidomastoid. It is generally accepted that to consistently elicit a startle reflex, the SAS must be both intense and unpredictable. However, it remains unclear what effect explicit foreknowledge of an impending SAS has on the effectiveness of a SAS to elicit a startle reflex when preparing a motor response...
October 13, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Ebru Yalın İmamoğlu, Ayşe Güler Eroğlu
AIM: To investigate ventricular arrhythmias in children with primary mitral valve prolapse and to evaluate its relation with QT length, QT dispersion, autonomic function tests and heart rate variability measurements. MATERIAL AND METHODS: Fourty two children with mitral valve prolapse and 32 healthy children were enrolled into the study. Twelve-lead electrocardiograms, autonomic function tests, echocardiography and 24-hour rhythm Holter tests were performed. Electrocardiograms were magnified digitally...
September 2016: Türk Pediatri Arşivi
Emer McGowan, Emma Stokes
BACKGROUND: Health service reform, physiotherapy graduate unemployment, and the impending introduction of state regulation mean that physiotherapists in Ireland today are facing many challenges. Leadership is needed to ensure that the profession will be able to adapt to the demands and inevitable changes ahead. OBJECTIVE: To investigate the perceptions of physiotherapists in Ireland of leadership and leadership characteristics, and to explore their participation in leadership development training...
October 13, 2016: Physiotherapy Theory and Practice
Paul M Speight, Joel Epstein, Omar Kujan, Mark W Lingen, Toru Nagao, Kannan Ranganathan, Pablo Vargas
Screening for oral cancer should be defined as the application of a test to people who are apparently free of disease to identify those who may have oral cancer and to distinguish them from those who may not. The aim of the test is not to be diagnostic but to identify changes that may be the earliest signs of impending disease. Defined in this way, screening is an ongoing public health measure, often funded by governments. A screening program must do no harm and must be cost effective. Governments demand that strict evidence of benefits and cost effectiveness be met before a program may be implemented...
September 9, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Wei Long Ng, Shuai Wang, Wai Yee Yeong, May Win Naing
No abstract text is available yet for this article.
October 7, 2016: Trends in Biotechnology
Robert J M Hermosillo, Jacqueline Carmody, Nazum Ugoalah, Ji-Hang Lee, Gordon Binsted, Paul van Donkelaar
The authors characterized how motor planning influences temporal order judgment (TOJ) tasks. They examined this by applying vibrotactile stimulation during the planning stages of a bimanual arm movement that would bring the arms into a crossed configuration. The authors have previously shown that planning to cross the arms induces a subjective reversal of spatially defined temporal order judgments that evolves over the course of the planning period. It was unclear, however, whether this effect is modulated by the extent to which the arms would be crossed after movement...
August 11, 2016: Journal of Motor Behavior
Sebastian Hormigo, German Vega-Flores, Manuel A Castro-Alamancos
: Engrained avoidance behavior is highly adaptive when it keeps away harmful events and can be highly maladaptive when individuals elude harmless situations in anxiety disorders, but the neural circuits that mediate avoidance are poorly understood. Using DREADDs and optogenetics in mice, we show that the output of the basal ganglia through the substantia nigra pars reticulata (SNr) controls active avoidance. SNr excitation blocks avoidance to a conditioned sensory stimulus while preserving the ability to escape the harmful event...
October 5, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Virginia Ahalt, Nilay Tanık Argon, Serhan Ziya, Jeff Strickler, Abhi Mehrotra
According to American College of Emergency Physicians, emergency department (ED) crowding occurs when the identified need for emergency services exceeds available resources for patient care in the ED, hospital, or both. ED crowding is a widely reported problem and several crowding scores are proposed to quantify crowding using hospital and patient data as inputs for assisting healthcare professionals in anticipating imminent crowding problems. Using data from a large academic hospital in North Carolina, we evaluate three crowding scores, namely, EDWIN, NEDOCS, and READI by assessing strengths and weaknesses of each score, particularly their predictive power...
October 4, 2016: Health Care Management Science
Ida Odh, Martina Löfving, Kicki Klaeson
PURPOSE: In Sweden, approximately 500 people between the ages of 15 and 39 are diagnosed with cancer each year. When someone is diagnosed with a life-threatening disease, existential issues are easily triggered. Young adults are in a developmental phase of life and are exposed to an extra amount of pressure. The Internet and social media are a daily part of the life of young adults and the use of blogs is common. The aim of this study was to elucidate the theoretical framework of Yalom and his four 'givens' expressed in blogs written by young adults living with various cancer diagnoses in Sweden...
October 2016: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
Keith A Vossel, Kamalini G Ranasinghe, Alexander J Beagle, Danielle Mizuiri, Susanne M Honma, Anne F Dowling, Sonja M Darwish, Victoria Van Berlo, Deborah E Barnes, Mary Mantle, Anna M Karydas, Giovanni Coppola, Erik D Roberson, Bruce L Miller, Paul A Garcia, Heidi E Kirsch, Lennart Mucke, Srikantan S Nagarajan
OBJECTIVE Seizures are more frequent in patients with Alzheimer's disease (AD) and can hasten cognitive decline. However, the incidence of subclinical epileptiform activity in AD and its consequences are unknown. Motivated by results from animal studies, we hypothesized higher than expected rates of subclinical epileptiform activity in AD with deleterious effects on cognition. METHODS We prospectively enrolled 33 patients (mean age 62 years) who met criteria for AD, but had no history of seizures, and 19 age-matched, cognitively normal controls...
October 1, 2016: Annals of Neurology
P Padmapriya, V Senthil Kumar, R Senthil Raja, A Khaleefathullah Sheriff, T S Uma, S Mohana, Kavita Arunagiri, A Anupama, N Saran, R Kiruba, K Saravana Murali, B V Suresh Babu, N Nivas Chakravarthy, K Saraswathi, K Kaveri, P Gunasekaran
Dengue is a public health problem with an increasing global incidence and geographic distribution in almost all tropical and subtropical countries, with a transition from epidemic to endemic occurrence. In this study, we report a six-year analysis (2009-2014) performed at the Department of Virology, King Institute of Preventive Medicine, Chennai, Tamil Nadu, India. Our data confirm earlier findings that dengue is highly endemic in Chennai. In the present study, 10,099 serum samples from suspected dengue cases were tested for IgM ELISA (NIV Capture) and IgG Panbio ELISA (Australia)...
September 30, 2016: Archives of Virology
Ravi Gondhalekar, Eyal Dassau, Francis J Doyle
A novel Model Predictive Control (MPC) law for an Artificial Pancreas (AP) to automatically deliver insulin to people with type 1 diabetes is proposed. The MPC law is an enhancement of the authors' zone-MPC approach that has successfully been trialled in-clinic, and targets the safe outpatient deployment of an AP. The MPC law controls blood-glucose levels to a diurnally time-dependent zone, and enforces diurnal, hard input constraints. The main algorithmic novelty is the use of asymmetric input costs in the MPC problem's objective function...
September 2016: Automatica: the Journal of IFAC, the International Federation of Automatic Control
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"