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He-Feng Huang

Yanyan Fang, Zhiqiang Nie, Jinzhong Yang, Qingqi Die, Yajun Tian, Feng Liu, Jie He, Jianyuan Wang, Qifei Huang
Soil, air, tree bark, rice, wheat, invertebrates, and chicken tissues around a typical endosulfan-contaminated site were analyzed in each season in each of two years. The total endosulfan (the sum of α-, β-endosulfan and endosulfan sulfate) were significantly different in soil and air samples collected in the four seasons (P < 0.01) and the mean concentrations were 6.53 ng/g dry weight (d.w.) and 2.40 ng/m3 , respectively, in autumn, 3.32 ng/g d.w. and 2.48 ng/m3 , respectively, in winter, 2...
June 12, 2018: Ecotoxicology and Environmental Safety
Renyao Huang, Li He, Tao Zhang, Dianqing Li, Pinggui Tang, Yongjun Feng
It is of great and increasing interest to explore porous adsorption films to reduce heavy metal ions in aqueous solution. Here, we for the first time fabricated carbon paper@magnesium silicate (CP@MS) composite films for the high-efficiency removal of Zn2+ and Cu2+ by a solid-phase transformation from hydromagnesite coated carbon paper (CP@MCH) precursor film in a hydrothermal route, and detailedly examined adsorption process for Zn2+ and Cu2+ as well as the adsorption mechanism. The suitable initial pH range is beyond 4...
June 14, 2018: ACS Applied Materials & Interfaces
Zhong-You Zeng, Zhao-Wan Xu, Deng-Wei He, Xing Zhao, Wei-Hu Ma, Wen-Fei Ni, Yong-Xing Song, Jian-Qiao Zhang, Wei Yu, Xiang-Qian Fang, Zhi-Jie Zhou, Nan-Jian Xu, Wen-Jian Huang, Zhi-Chao Hu, Ai-Lian Wu, Jian-Fei Ji, Jian-Fu Han, Shun-Wu Fan, Feng-Dong Zhao, Hui Jin, Fei Pei, Shi-Yang Fan, De-Xiu Sui
OBJECTIVE: To analyze the early complications and causes of oblique lateral interbody fusion, and put forward preventive measures. METHODS: There were 235 patients (79 males and 156 females) analyzed in our study from October 2014 to May 2017. The average age was 61.9 ± 0.21 years (from 32 to 83 years). Ninety-one cases were treated with oblique lateral interbody fusion (OLIF) alone (OLIF alone group) and 144 with OLIF combined with posterior pedicle screw fixation through the intermuscular space approach (OLIF combined group)...
May 2018: Orthopaedic Surgery
Xianshuang Wang, An Li, Nasrullah Wazir, Shiqi Huang, Shuai Guo, Liang Liang, Min Zhang, Bingsuo Zou, Yan Hao, Feng He, Yufeng Bai, Weipeng Sun, Mulin Hu, Ruibin Liu
Improvement in detection accuracy is an important and hot topic for laser induced breakdown spectroscopy (LIBS). Discharged-pulse assisted (DPA) plasma has been investigated as an effective way to enhance analytical capabilities and accuracy of LIBS. Most of reported DPA experiments have been performed using high voltage and power to comprehend spectrum enhancement. For safety concerns and maneuverability of LIBS equipment; low power and small current discharge are viable for industrial application. In this paper, the enhanced spectra with many extra peaks and higher line intensities were also detected, realized by a low-power discharge assisted LIBS (Max...
May 28, 2018: Optics Express
Tanzil Ur Rahman, Kamran Ullah, Meng-Xi Guo, Hai-Tao Pan, Juan Liu, Jun Ren, Lu-Yang Jin, Yu-Zhong Zhou, Yi Cheng, Jian-Zhong Sheng, He-Feng Huang
High androgen level impairs endometrial receptivity in women experiences the recurrent miscarriage. The mechanism of androgen actions on endometrium is still uncertain. We hypothesized that androgen has a direct effect on the endometrium in women with recurrent miscarriage. In the present study, we assess the impact of androgen (A2 ) at high concentration (10-7 M) on Ishikawa cells compared with the physiological concentration of androgen (10-9 M). To go into deeper analysis, we use global stable isotopes labeled profiling tactic using iTRAQ reagents, followed by 2D LC-MS/MS...
May 15, 2018: Oncotarget
Quan Zhou, Xi Hong, He-Zhen Cui, Shuang Huang, Ying Yi, Xiu-Feng Hou
Herein, a general and practical route to 2-(2-aminophenyl)- and 2-(2-alkoxyphenyl)-substituted benzazoles by nucleophilic aromatic substitution (SN Ar) is described. Upon treatment with Cs2 CO3 , the formation of C-N, C-O bonds occur between fluorine-substituted 2-aryl benzazoles and a diverse range of nitrogen, oxygen nucleophiles to provide the targets in good to excellent yields. Commercially available nucleophiles and high atom economy are notable features of the protocol. Meanwhile, the construction of C(sp2 )-C(sp3 ) bond was also furnished in the presence of palladium catalyst...
June 5, 2018: Journal of Organic Chemistry
Li Hu, Fengli He, Meifeng Huang, Meihua Peng, Zhiguang Zhou, Feng Liu, Yan-Shan Dai
Nuclear factors of activated T-cells (NFAT) c3 has a prominent role in regulation of proinflammatory factors in immune cells. The classically activated M1 macrophages are key players in the initiation and maintenance of adipose tissue (AT) inflammation. The role of NFATc3 in obesity and AT inflammation is unknown. We set out to determine how deficiency of NFATc3 effected macrophage polarization, inflammation and insulin resistance in visceral adipose tissue of high fat diet (HFD)-fed mice. Nfatc3-/- and wild type (WT) mice were fed a HFD for 8 to 17 weeks...
June 4, 2018: Journal of Molecular Endocrinology
Shuxian Wu, Yajuan Huang, Siping Li, Haishen Wen, Meizhao Zhang, Jifang Li, Yun Li, Changwei Shao, Feng He
Japanese flounder (Paralichthys olivaceus) undergoes metamorphosis by changing its body from the larval to the juvenile form, and this process involves muscle development. Smyd1, a histone methyltransferase, plays a role in the skeletal muscle. In the present study, the Smyd1a and Smyd1b expression patterns and their 5' UTR and exon 1 DNA methylation levels were analyzed during metamorphosis of the Japanese flounder. Sample were analyzed 21 days post-hatching (dph) (with no migration of right eye; M1stage), 28 dph (during migration of right eye; M2 stage), and 35 dph (after migration of right eye; M3 stage)...
June 1, 2018: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
Jing Xia, Xiao He, Li-Jing Du, Yue-Yue Liu, Guo-Jin You, Shu-Yun Li, Ping Liu, San-Jie Cao, Xin-Feng Han, Yong Huang
Avian infectious bronchitis (IB) is a highly contagious disease, and hazardous to the poultry industry. Immune failure often occurs due to the emergence of new serotypes or field strains antigenically different from the vaccine strains. To prepare a candidate vaccine against the prevalent avian infectious bronchitis virus (IBV) in China, the GI-19/QX-like field isolate Sczy3 was selected as the progenitor strain and attenuated via passaging in chicken embryo kidney (CEK) cells for 100 times. The 100th generation of CEK-adapted strain, designated SczyC100, was safe to use on one-day old specific pathogen-free (SPF) chicken as determined by pathogenicity and virulence reversion test...
May 30, 2018: Vaccine
Lingwen Jiang, Mingsong Zou, He Huang, Xuelei Feng
Based on the three-dimensional sono-elasticity theory for ship structures, the Green's function is incorporated and an integrated calculation method of acoustic radiation and propagation for floating bodies in shallow water considering the sound velocity profile is proposed. The near-field and arbitrary far-field acoustic radiation problem can be efficiently calculated. A numerical example of a rigid sphere is given and the results are compared with the finite element method solution to validate the reliability and demonstrate improvements in efficiency...
May 2018: Journal of the Acoustical Society of America
Yu Shi, Olga A Guryanova, Wenchao Zhou, Chong Liu, Zhi Huang, Xiaoguang Fang, Xiuxing Wang, Cong Chen, Qiulian Wu, Zhicheng He, Wei Wang, Wei Zhang, Tao Jiang, Qing Liu, Yaping Chen, Wenying Wang, Jingjing Wu, Leo Kim, Ryan C Gimple, Hua Feng, Hsiang-Fu Kung, Jennifer S Yu, Jeremy N Rich, Yi-Fang Ping, Xiu-Wu Bian, Shideng Bao
Glioblastoma (GBM) is the most lethal primary brain tumor and is highly resistant to current treatments. GBM harbors glioma stem cells (GSCs) that not only initiate and maintain malignant growth but also promote therapeutic resistance including radioresistance. Thus, targeting GSCs is critical for overcoming the resistance to improve GBM treatment. Because the bone marrow and X-linked (BMX) nonreceptor tyrosine kinase is preferentially up-regulated in GSCs relative to nonstem tumor cells and the BMX-mediated activation of the signal transducer and activator of transcription 3 (STAT3) is required for maintaining GSC self-renewal and tumorigenic potential, pharmacological inhibition of BMX may suppress GBM growth and reduce therapeutic resistance...
May 30, 2018: Science Translational Medicine
Shun Zhi He, Jing Li, Hong Chu Bao, Mei Mei Wang, Xin Rong Wang, Xin Huang, Feng Hua Li, Wei Zhang, An Li Xu, Hao Cui Fang, Yang Xing Sheng
The focus of the current study was a G protein‑coupled estrogen receptor (GPER)/microRNA (miR)‑148a/human leukocyte antigen‑G (HLA‑G) signaling pathway in ovarian endometriosis. Reverse transcription‑quantitative polymerase chain reaction was performed to analyze the changes in miR‑148a expression. A MTT assay, flow cytometry and caspase‑3/9 activity assays were performed to analyze cell proliferation, apoptosis and caspase‑3/9 activity levels, respectively. Protein expression was measured using western blot analysis...
May 21, 2018: Molecular Medicine Reports
Xinyi Yu, Feng Liu, Liyi Zeng, Fang He, Ruyi Zhang, Shujuan Yan, Zongyue Zeng, Yi Shu, Chen Zhao, Xingye Wu, Jiayan Lei, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Liping An, Shifeng Huang, Xiaojuan Ji, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Yixiao Feng, Bo Huang, Wei Liu, Bo Zhang, Zhengyu Dai, Xi Wang, Bo Liu, Rex C Haydon, Hue H Luu, Hua Gan, Tong-Chuan He, Liqun Chen
BACKGROUND/AIMS: As the most lethal urological cancers, renal cell carcinoma (RCC) comprises a heterogeneous group of cancer with diverse genetic and molecular alterations. There is an unmet clinical need to develop efficacious therapeutics for advanced, metastatic and/or relapsed RCC. Here, we investigate whether anthelmintic drug Niclosamide exhibits anticancer activity and synergizes with targeted therapy Sorafenib in suppressing RCC cell proliferation. METHODS: Cell proliferation and migration were assessed by Crystal violet staining, WST-1 assay, cell wounding and cell cycle analysis...
May 24, 2018: Cellular Physiology and Biochemistry
Abishek Jung Poudel, Feng He, Lixia Huang, Lin Xiao, Guang Yang
A supramolecular hydrogel system was prepared by the host-guest interaction between the α-cyclodextrin (α-CD) and poly (ethylene glycol) (PEG) chains of the poly (ethylene glycol)-block-poly (lactic acid) (PEG-b-PLA) micelles. The formation of inclusion complex (IC) crystals between α-CD and the PEG chains of the micelles was verified by different techniques. Rheological studies indicated that the gelation kinetics and the mechanical strength of the hydrogels could be modulated by the α-CD concentration...
August 15, 2018: Carbohydrate Polymers
Jun Ren, Yi Cheng, Zhen-Hua Ming, Xin-Yan Dong, Yu-Zhong Zhou, Guo-Lian Ding, Hai-Yan Pang, Tanzil Ur Rahman, Rubab Akbar, He-Feng Huang, Jian-Zhong Sheng
BACKGROUND: The existing reports about intergenerational or transgenerational effects of intrauterine hyperglycemia have included both intrauterine and postnatal metabolic exposure factors, while the impact of intrauterine hyperglycemia per se has not been assessed alone. A number of studies suggest DNA methylation reprogramming of gametes plays a crucial role in the metabolic inheritance, but it is unclear when and how DNA methylation patterns are altered when exposed to intrauterine hyperglycemia...
May 25, 2018: Epigenetics & Chromatin
Junlei He, Meixin Feng, Yaozong Zhong, Jin Wang, Rui Zhou, Hongwei Gao, Yu Zhou, Qian Sun, Jianxun Liu, Yingnan Huang, Shuming Zhang, Huaibing Wang, Masao Ikeda, Hui Yang
Direct bandgap III-V semiconductor lasers grown on silicon (Si) are highly desired for monolithic integration with Si photonics. Fabrication of semiconductor lasers with a Fabry-Pérot cavity usually includes facet cleavage, however, that is not compatible with on-chip photonic integration. Etching as an alternative approach holds a great advantage in preparing cavity mirrors with no need of breaking wafer into bars. However, gallium nitride (GaN) sidewalls prepared by dry etching often have a large roughness and etching damages, which would cause mirror loss due to optical scattering and carrier injection loss because of surface non-radiative recombination...
May 21, 2018: Scientific Reports
Cheng Chang, Minghui Wu, Dongsheng He, Yanling Pei, Chao-Feng Wu, Xuefeng Wu, Hulei Yu, Fangyuan Zhu, Kedong Wang, Yue Chen, Li Huang, Jing-Feng Li, Jiaqing He, Li-Dong Zhao
Thermoelectric technology enables the harvest of waste heat and its direct conversion into electricity. The conversion efficiency is determined by the materials figure of merit ZT Here we show a maximum ZT of ~2.8 ± 0.5 at 773 kelvin in n-type tin selenide (SnSe) crystals out of plane. The thermal conductivity in layered SnSe crystals is the lowest in the out-of-plane direction [two-dimensional (2D) phonon transport]. We doped SnSe with bromine to make n-type SnSe crystals with the overlapping interlayer charge density (3D charge transport)...
May 18, 2018: Science
Qiang Cai, Lulu Qiao, Ming Wang, Baoye He, Feng-Mao Lin, Jared Palmquist, Hsien-Da Huang, Hailing Jin
Some pathogens and pests deliver small RNAs (sRNAs) into host cells to suppress host immunity. Conversely, hosts also transfer sRNAs into pathogens and pests to inhibit their virulence. Although sRNA trafficking has been observed in a wide variety of interactions, how sRNAs are transferred, especially from hosts to pathogens/pests, is still unknown. Here we show that host Arabidopsis cells secrete exosome-like extracellular vesicles to deliver sRNAs into fungal pathogen Botrytis cinerea These sRNA-containing vesicles accumulate at the infection sites and are taken up by the fungal cells...
May 17, 2018: Science
Tian Fang, Dan-Dan Liu, He-Ming Ning, Dan Liu, Jing-Ya Sun, Xiao-Jing Huang, Yu Dong, Mei-Yu Geng, Shi-Feng Yun, Jun Yan, Rui-Min Huang
Modified citrus pectin (MCP) is a carbohydrate enriched complex, which has been implicated in cancer treatment and prevention. However, the effects of MCP on urinary bladder cancer (UBC) are unknown. In this study, MCP was first tested in T24 and J82 human UBC cells and showed the inhibition of cell viability by the sulforhodamine B (SRB) assay. The MCP-treated UBC cells exhibited G2 /M phase arrest with the decrease of Cyclin B1 and phosphorylated Cdc2. Caspase-3 was also activated, leading to the cleavage of Caspase-3 and PARP...
May 16, 2018: Acta Pharmacologica Sinica
Li-Rong Wu, Huan-Feng Zhu, Jianhua Xu, Xue-Song Jiang, Li Yin, Ning Jiang, Dan Zong, Fei-Jiang Wang, Sheng-Fu Huang, Xiu-Hua Bian, Jian-Feng Wu, Dan Song, Wen-Jie Guo, Ju-Ying Liu, Xia He
Background : This study aimed to compare concurrent chemoradiotherapy (CCRT) plus cetuximab (C) with CCRT alone in locoregionally advanced nasopharyngeal carcinoma(NPC). Methods : A total of 682 locoregionally advanced NPC patients who had undergone chemoradiotherapy with or without cetuximab were included. Propensity score-matching method was used to match patients. Progression-free survival (PFS), overall survival (OS), locoregional relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) were compared between the two treatment arms...
2018: Journal of Cancer
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