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Lobar pneumonia

Chunrong Li, Xiujuan Wu, Hehe Qi, Yanwei Cheng, Bing Zhang, Hongwei Zhou, Xiaohong Lv, Kangding Liu, Hong-Liang Zhang
BACKGROUND: Reversible splenial lesion syndrome (RESLES) is a rare clinico-radiological disorder with unclear pathophysiology. Clinically, RESLES is defined as reversible isolated splenial lesions in the corpus callosum, which can be readily identified by magnetic resonance imaging (MRI) and usually resolve completely over a period of time. RESLES could be typically triggered by infection, antiepileptic drugs (AEDs), poisoning, etc. More factors are increasingly recognized. METHODS AND RESULTS: We reported herein an 18-year-old female patient with lobar pneumonia who developed mental abnormalities during hospitalization...
September 2016: Medicine (Baltimore)
Marcello DiStasio, Karoly Balogh
No abstract text is available yet for this article.
2016: IDCases
Shinichi Okuzumi, Naoto Minematsu, Mamoru Sasaki, Kazuma Ohsawa, Marohito Murakami
Mycobacterium avium complex (MAC) infection is a major medical concern in Japan because of its increased prevalence and associated mortality. A common radiological feature in pulmonary MAC infection is a mixture of two basic patterns: fibrocavitary and nodular bronchiectatic; however, lobar consolidation is rare. We report an 83-year-old man with lobar caseous pneumonia caused by pulmonary MAC infection. Radiological findings were predominantly composed of dense lobar consolidation and ground-glass opacity...
September 2016: Respirology Case Reports
Farah Jazuli, Terence Lynd, Jordan Mah, Michael Klowak, Dale Jechel, Stefanie Klowak, Howard Ovens, Sam Sabbah, Andrea K Boggild
BACKGROUND: Fever in the returned traveller is a potential medical emergency warranting prompt attention to exclude life-threatening illnesses. However, prolonged evaluation in the emergency department (ED) may not be required for all patients. As a quality improvement initiative, we implemented an algorithm for rapid assessment of febrile travelers (RAFT) in an ambulatory setting. METHODS: Criteria for RAFT referral include: presentation to the ED, reported fever and travel to the tropics or subtropics within the past year...
2016: BMJ Open
Dong-Mei Yuan, Yan-Wen Yao, Qian Li, Chen-Yang Liu, Pei Li, E-Hong Cao, Xin-Wu Xiao, Xin Su, Yong Song
Bronchioloalveolar carcinoma (BAC) is a unique lung neoplasm with variable forms, such as single nodular, multifocal and lobar pneumonic types. The pneumonic type BAC is often difficult to differentiate from pneumonia. Here we present a case of 63-year-old Chinese male, who had recurrent cough, white sputum with pneumonic lesions in left lower lobe. He suffered from lung biopsies for three times, and finally diagnosed as high differentiated adenocarcinoma 8 years later. He was treated with four cycles of pemetrexed and cisplatin, and four cycles of docetaxel and nedaplatin...
June 2016: Translational Lung Cancer Research
James Jackson Mulvany, Andrew Weatherall, Amanda Charlton, Hiran Selvadurai
Congenital lobar emphysema (CLE), a rare condition that usually presents in the neonatal period, can be a diagnostic and therapeutic challenge for the treating clinician. If unrecognised, it is a significant risk at the time of anaesthetic induction. We describe a case of CLE in a 3-month-old boy who was initially treated for suspected aspiration pneumonia at the referring hospital. We highlight the importance of careful consideration of common childhood respiratory illness as well as pneumothorax in the differential diagnosis, and the significance of appropriate preoperative anaesthetic management...
2016: BMJ Case Reports
C Pascual, V Trenchs, S Hernández-Bou, A Català, A F Valls, C Luaces
There are no unified protocols governing the management of healthy children with febrile neutropenia in the emergency department (ED). Conservative management is the norm, with admission and empirical broad-spectrum antibiotics prescribed, although viral infections are considered the most frequent etiology. The aim of this study was to describe the clinical outcomes and identified etiologies of unsuspected neutropenia in febrile immunocompetent children assessed in the ED. This was a retrospective study: well-appearing healthy children <18 years old with febrile moderate [absolute neutrophil count (ANC) 500-999 neutrophils ×10(9)/l] or severe (ANC <500 neutrophils ×10(9)/l) neutropenia diagnosed in ED between 2005 and 2013 were included...
October 2016: European Journal of Clinical Microbiology & Infectious Diseases
Abhishek Chinya, Prince Raj Pandey, Shandip Kumar Sinha, Yogesh Kumar Sarin
Congenital lobar emphysema (CLE) is a rare but life-threatening congenital anomaly leading to respiratory distress in early childhood. Diagnosis requires a strong clinical suspicion. We report a case of a 31/2-month-old infant who was initially diagnosed with pneumonia requiring multiple hospital admissions. After computed tomography of the thorax, a diagnosis on CLE was made. The child was planned for surgery in the next available routine operation theatre. However, suddenly in the evening, she developed respiratory distress and needed emergency surgical intervention...
May 2016: Lung India: Official Organ of Indian Chest Society
Eri Kumade, Norihiro Furusyo, Norito Takeshima, Yasuhiro Kishihara, Fujiko Mitsumoto-Kaseida, Yoshitaka Etoh, Masayuki Murata, Jun Hayashi
Klebsiella pneumoniae often causes pneumonia and other infections in heavy drinkers and patients with diabetes. Pneumonia caused by Klebsiella rhinoscleromatis, a subspecies of K. pneumoniae, has not been previously reported. We report a case of pneumonia caused by K. rhinoscleromatis. A 68-year-old man with type 2 diabetes visited our department complaining fever and fatigue for 10 days and cough and bloody sputum for two days. His Japan Coma Scale score was I-1, body temperature 38.3 °C, blood pressure 85/51 mmHg, pulse 135 bpm, and peripheral capillary oxygen saturation level 92% (room air)...
October 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
Shuai-Shuai Liu, Li-Jun Song, Fan-Zheng Meng, Li Peng, Yu-Huan Liu
OBJECTIVE: To investigate the early predictors of necrotizing pneumonia in children. METHODS: The clinical data of 43 children with necrotizing pneumonia and 83 children with lobar pneumonia were retrospectively analyzed. Sex, age, the number of days with fever, laboratory examination results, and bronchoscopic findings were compared between the two groups. The multiple logistic regression analysis was used to identify the early predictors of necrotizing pneumonia...
May 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
K Kassab, M Karnib, P K Bou-Khalil, A R Bizri
Actinomycosis is a chronic suppurative infection caused by filamentous Gram-positive bacilli, leading to a purulent discharge due to sulfur granule formation. Thoracic actinomycosis represents around 20% of Actinomyces infections, with endobronchial involvement being fairly uncommon. Pulmonary actinomycosis should be considered in the differential diagnosis of non-resolving lobar pneumonia or a lobar mass suspicious for malignancy on endobronchial biopsy. A case of endobronchial actinomycosis presenting as post-obstructive pneumonia and mimicking right upper lobe endobronchial carcinoma, which was associated with foreign body aspiration, is reported here...
July 2016: International Journal of Infectious Diseases: IJID
Rajendra Prasad Janapatla, Mei-Hua Hsu, Wan-Ting Liao, Kun-Yi Chien, Hao-Yuan Lee, Cheng-Hsun Chiu
Streptococcus pneumoniae, a neuraminidase-producing pathogen, can cause invasive pneumococcal disease (IPD) with or without hemolytic uremic syndrome (HUS) in humans. We aimed to identify serum sialoglycoproteins that are targeted by neuraminidases in severe pneumococcal infection. We hypothesized that serum sialoglycoprotein such as fetuin-A can serve as a biomarker to predict IPD or HUS. We constructed serum sialoglycoprotein profiles before and after pneumococcal neuraminidase treatment using liquid chromatography-tandem mass spectrometry (LC-MS/MS), a proteomic approach...
March 2016: Medicine (Baltimore)
Yunqiang Nie, Cuiyun Li, Jingling Zhang, Hui Wang, Ping Han, Xin Lv, Xinyi Xu, Miao Guo
BACKGROUND: This article discusses the value of high-resolution computed tomography (HRCT) in the diagnosis and treatment of pulmonary infections. Lung infection caused by pathogens is an important cause of death. Traditional methods to treat lung infection involved empirical antibiotic therapy. Thin-slice CT scanning is widely used in the clinical setting, and HRCT scan can very clearly show alveolar and bronchiolar involvement of infection. MATERIAL/METHODS: In total, 178 patients with community-acquired pneumonia (CAP) were enrolled...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Michael G Aman, Robert L Findling, Antonio Y Hardan, Robert L Hendren, Raun D Melmed, Ola Kehinde-Nelson, Hai-An Hsu, Joel M Trugman, Robert H Palmer, Stephen M Graham, Allyson T Gage, James L Perhach, Ephraim Katz
OBJECTIVE: Abnormal glutamatergic neurotransmission is implicated in the pathophysiology of autism spectrum disorder (ASD). In this study, the safety, tolerability, and efficacy of the glutamatergic N-methyl-d-aspartate (NMDA) receptor antagonist memantine (once-daily extended-release [ER]) were investigated in children with autism in a randomized, placebo-controlled, 12 week trial and a 48 week open-label extension. METHODS: A total of 121 children 6-12 years of age with Diagnostic and Statistical Manual of Mental Disorders, 4th ed...
March 15, 2016: Journal of Child and Adolescent Psychopharmacology
Michael Seear, Shally Awasthi, Vishwanath Gowraiah, Rashmi Kapoor, Aradhana Awasthi, Anilkumar Verma, Saud Al-Shabibi, Claire Gowdy
OBJECTIVE: To test the predictive accuracy and reporting reproducibility of digital chest radiographs under low-resource conditions. METHODS: One hundred thirty four tachypneic children who presented to two Indian hospitals were enrolled. Based on review of 16 variables recorded in the Emergency Room (ER) by a senior pediatrician, children were given one of the four clinical diagnoses: pneumonia, wheezy disease, mixed and non-respiratory. Every child also had a digital CXR...
September 2016: Indian Journal of Pediatrics
Silvia Mongodi, Gabriele Via, Martin Girard, Isabelle Rouquette, Benoit Misset, Antonio Braschi, Francesco Mojoli, Bélaïd Bouhemad
BACKGROUND: Lung ultrasound (LUS) has been successfully applied for monitoring aeration in ventilator-associated pneumonia (VAP) and to diagnose and monitor community-acquired pneumonia. However, no scientific evidence is yet available on whether LUS reliably improves the diagnosis of VAP. METHODS: In a multicenter prospective study of 99 patients with suspected VAP, we investigated the diagnostic performance of LUS findings of infection, subpleural consolidation, lobar consolidation, and dynamic arborescent/linear air bronchogram...
April 2016: Chest
Sriram Ramgopal, Yaron Ivan, Avinash Medsinge, Richard A Saladino
Necrotizing pneumonias occur infrequently in children but may be associated with significant morbidity. If not adequately treated, necrotizing pneumonia may lead to complications including bronchopleural fistula, empyema, respiratory failure, and septic shock. Staphylococcus aureus is the most commonly implicated agent, followed by Streptococcus pneumoniae. Antimicrobial treatment is the cornerstone of management, although surgical drainage may be required in some cases. We present the case of a 14-month-old child with fever and cough that persisted despite treatment with typical first-line oral antimicrobial therapy...
January 16, 2016: Pediatric Emergency Care
Jonathan H Chung, Gwen Huitt, Kunihiro Yagihashi, Stephen B Hobbs, Anna V Faino, Bradley D Bolster, Jürgen Biederer, Michael Puderbach, David A Lynch
RATIONALE: Computed tomographic (CT) radiography is the reference standard for imaging Mycobacterium avium complex (MAC) lung infection. Magnetic resonance imaging (MRI) has been shown to be comparable to CT for characterizing other pulmonary inflammatory conditions, but has not been rigorously tested for imaging MAC pneumonia. OBJECTIVES: To determine the feasibility of pulmonary MRI for imaging MAC pneumonia and to assess the degree of agreement between MRI and CT for assessing the anatomic features and lobar extent of MAC lung infections...
January 2016: Annals of the American Thoracic Society
Paula Moreno, Antonio Alvarez, Guadalupe Carrasco, Javier Redel, Hugo Dario Guaman, Carlos Baamonde, Francisco Javier Algar, Francisco Cerezo, Angel Salvatierra
OBJECTIVES: The survival benefit of lung transplantation (LTx) for cystic fibrosis (CF) patients is well demonstrated. We aim to compare children and adult CF recipients to assess whether there are differences in survival and clinical outcomes, and to identify risk factors for mortality. METHODS: A retrospective analysis of 442 consecutive LTx performed at our institution in a 20-year period was conducted. CF patients were distributed into two groups: children (age <18 years) and adults (age ≥18 years)...
May 2016: European Journal of Cardio-thoracic Surgery
Masakazu Kimura, Kuniharu Miyajima, Masakazu Kojika, Takafumi Kono, Harubumi Kato
Intractable advanced lung cancer can be treated palliatively with photodynamic therapy (PDT) combined with chemotherapy to remove central and peripheral (lobar or segmental bronchi) bronchial stenosis and obstruction. We present data for 12 (eight men, four women) consecutive patients with 13 advanced non-small cell lung carcinomas in whom curative operations were contraindicated, who underwent PDT combined with chemotherapy for local control of the intraluminal lesions. The mean age was 73.3 years (range, 58-80 years), and the stages of cancer were IIA-IV...
2015: International Journal of Molecular Sciences
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