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Lobar pneumonia

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https://www.readbyqxmd.com/read/27927829/lesson-of-the-month-1-lobar-pulmonary-consolidation-in-an-immunocompromised-host
#1
Daniel J Reynolds, Carl A Andersen, Sumedh S Hoskote, Hee Eun Lee, Aditya Raghunathan, Sanjay Kalra, Andrew H Limper
A 19-year-old male with a history of idiopathic panuveitis, currently taking methotrexate and infliximab, presented to our institution with 6 weeks of cough, dyspnoea and fevers. He had failed outpatient antimicrobial therapy. Computerised tomography (CT) of the chest revealed the presence of a lobar pneumonia and he was treated with broad spectrum antibiotics, which did not improve his symptoms. Bronchoalveolar lavage was performed with a transbronchial lung biopsy because of the diagnostic uncertainty of the patient's presentation...
December 2016: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/27924204/combined-use-of-a-double-lumen-tube-and-fogarty-catheter-to-prevent-the-endobronchial-spread-of-infection-a-case-report
#2
Jaewon Kim, Hyelim Lee, Han Park, Chang-Young Jeong
Huntington's disease is a neurodegenerative disorder with an autosomal dominant inheritance pattern. Patients with Huntington's disease show an increased risk of aspiration pneumonia when the pharyngeal muscle is invaded. We report a case of advanced-stage Huntington's disease in which the patient received right middle lobectomy for a lung abscess caused by repeated aspiration. The best lung isolation technique has not yet been established in these patients. We successfully performed selective lobar isolation of the right lower and middle lobes using a double lumen tube and a Fogarty embolectomy catheter...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27899697/sudden-death-of-a-child-due-to-pyogenic-bacterial-myocarditis
#3
Asit K Sikary, Asit R Mridha, Chittaranjan Behera
Bacterial myocarditis is an uncommon condition and only a few fatal cases in adults are reported in the scientific literature. Death from acute bacterial myocarditis in children is extremely rare. We report an unusual case of fatal bacterial myocarditis in a seven-year-old girl, who had a history of cough for a month and fever for two days. She was given symptomatic treatment by a local physician without suspecting her clinical condition. Her condition rapidly deteriorated and she was brought in dead to the hospital...
November 28, 2016: Medico-legal Journal
https://www.readbyqxmd.com/read/27893684/ct-findings-of-small-cell-lung-carcinoma-can-recognizable-features-be-found
#4
Dongjun Lee, Ji Young Rho, Seunghun Kang, Koun Joy Yoo, Hye Jeong Choi
The purpose of this study was to clarify the recognizable computed tomography (CT) features of small cell lung carcinoma (SCLC).Contrast enhanced CT scans were reviewed retrospectively for mass location, mediastinal extension, and other concomitant findings in 142 patients with pathologically proven SCLC. SCLC was classified into hilar mass only (type I), hilar mass with ipsilateral mediastinal extension (type II), hilar mass with bilateral mediastinal extension (type III), and peripheral mass (type IV). When mediastinal lymphadenopathy (m-LAP) was indistinguishable from a hilar mass, we defined it as a mediastinal conglomerate mass (m-CM)...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27817772/-an-epidemiological-study-on-human-rhinovirus-c-in-hospitalized-children-with-respiratory-tract-infections
#5
Li Li, Wei Ji, Xue-Jun Shao, Jun Xu, Wu-Jun Jiang, Zheng-Rong Chen, Yong-Dong Yan
OBJECTIVE: To investigate the detection rates, epidemical characteristics, and clinical features of human rhinovirus C (HRV-C) in hospitalized children with respiratory tract infections (RTIs) in Suzhou, China. METHODS: A total of 1 702 hospitalized children with RTIs from January to December, 2014 were enrolled, and 1 702 nasopharyngeal aspirate samples were collected from all children. RT-PCR was used to measure HRV mRNA, and quantitative real-time PCR combined with high-resolution melting curve was used to measure HRV-C...
November 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27789057/a-case-control-study-of-community-acquired-acinetobacter-baumannii-pneumonia-and-melioidosis-pneumonia-in-northeast-thailand-an-emerging-fatal-disease-with-unique-clinical-features
#6
Samadhi Patamatamkul, Voravan Klungboonkrong, Pakawas Praisarnti, Kittitouch Jirakiat
Acinetobacter baumannii is the emerging cause of severe and often fatal gram-negative, community-acquired pneumonia (CAP-AB) in Thailand. Due to its rarity, its specific clinical features are ill defined. In this retrospective study, we compared the demographic data, risk factors, clinical characteristics, radiographic pattern, and microbiological data between CAP-AB and Burkholderia pseudomallei CAP (CAP-BP) to identify the clinical features and risk factors of CAP-AB. CAP-AB was associated with a more productive cough and a shorter duration of symptoms, while CAP-BP was associated with more musculoskeletal symptoms...
October 11, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27786573/effect-and-mechanism-of-calpains-on-pediatric-lobar-pneumonia
#7
Genquan Yin, Qiang Zeng, Haijin Zhao, Peiqiong Wu, Shaoxi Cai, Li Deng, Wenhui Jiang
BACKGROUND: Lobar pneumonia, one of the community-acquired pneumonia (CAP), is a common pediatric low respiratory tract infection. Calpains are Ca(2+)-activated cysteine proteases whose activation mechanism is elusive. The present study was undertaken to detect the role and mechanism of calpains in pediatric lobar pneumonia. MATERIAL AND METHODS: The human acute lung infection model (ALIM) was constructed and infected by Streptococcus. Enzyme-linked immunosorbent assay (ELISA) was used to measure interleukin (IL)-6, IL-8 and tumor necrosis factor (TNF)-α...
October 27, 2016: Bioengineered
https://www.readbyqxmd.com/read/27785538/cholinergic-pet-imaging-in-infections-and-inflammation-using-11-c-donepezil-and-18-f-feobv
#8
Nis Pedersen Jørgensen, Aage K O Alstrup, Frank V Mortensen, Karoline Knudsen, Steen Jakobsen, Line Bille Madsen, Dirk Bender, Peter Breining, Mikkel Steen Petersen, Mariane Høgsberg Schleimann, Frederik Dagnæs-Hansen, Lars C Gormsen, Per Borghammer
INTRODUCTION: Immune cells utilize acetylcholine as a paracrine-signaling molecule. Many white blood cells express components of the cholinergic signaling pathway, and these are up-regulated when immune cells are activated. However, in vivo molecular imaging of cholinergic signaling in the context of inflammation has not previously been investigated. METHODS: We performed positron emission tomography (PET) using the glucose analogue 18F-FDG, and 11C-donepezil and 18F-FEOBV, markers of acetylcholinesterase and the vesicular acetylcholine transporter, respectively...
October 26, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27684805/reversible-splenial-lesion-syndrome-associated-with-lobar-pneumonia-case-report-and-review-of-literature
#9
Chunrong Li, Xiujuan Wu, Hehe Qi, Yanwei Cheng, Bing Zhang, Hongwei Zhou, Xiaohong Lv, Kangding Liu, Hong-Liang Zhang
BACKGROUND: Reversible splenial lesion syndrome (RESLES) is a rare clinico-radiological disorder with unclear pathophysiology. Clinically, RESLES is defined as reversible isolated splenial lesions in the corpus callosum, which can be readily identified by magnetic resonance imaging (MRI) and usually resolve completely over a period of time. RESLES could be typically triggered by infection, antiepileptic drugs (AEDs), poisoning, etc. More factors are increasingly recognized. METHODS AND RESULTS: We reported herein an 18-year-old female patient with lobar pneumonia who developed mental abnormalities during hospitalization...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27679757/community-acquired-lobar-pneumonia-encountered-at-autopsy
#10
Marcello DiStasio, Karoly Balogh
No abstract text is available yet for this article.
2016: IDCases
https://www.readbyqxmd.com/read/27516892/pulmonary-mycobacterium-avium-infection-demonstrating-unusual-lobar-caseous-pneumonia
#11
Shinichi Okuzumi, Naoto Minematsu, Mamoru Sasaki, Kazuma Ohsawa, Marohito Murakami
Mycobacterium avium complex (MAC) infection is a major medical concern in Japan because of its increased prevalence and associated mortality. A common radiological feature in pulmonary MAC infection is a mixture of two basic patterns: fibrocavitary and nodular bronchiectatic; however, lobar consolidation is rare. We report an 83-year-old man with lobar caseous pneumonia caused by pulmonary MAC infection. Radiological findings were predominantly composed of dense lobar consolidation and ground-glass opacity...
September 2016: Respirology Case Reports
https://www.readbyqxmd.com/read/27473947/evaluation-of-a-programme-for-rapid-assessment-of-febrile-travelers-raft-a-clinic-based-quality-improvement-initiative
#12
Farah Jazuli, Terence Lynd, Jordan Mah, Michael Klowak, Dale Jechel, Stefanie Klowak, Howard Ovens, Sam Sabbah, Andrea K Boggild
BACKGROUND: Fever in the returned traveller is a potential medical emergency warranting prompt attention to exclude life-threatening illnesses. However, prolonged evaluation in the emergency department (ED) may not be required for all patients. As a quality improvement initiative, we implemented an algorithm for rapid assessment of febrile travelers (RAFT) in an ambulatory setting. METHODS: Criteria for RAFT referral include: presentation to the ED, reported fever and travel to the tropics or subtropics within the past year...
2016: BMJ Open
https://www.readbyqxmd.com/read/27413717/recurrent-pneumonia-in-left-lower-lobe-lasting-for-8-years-a-case-report
#13
Dong-Mei Yuan, Yan-Wen Yao, Qian Li, Chen-Yang Liu, Pei Li, E-Hong Cao, Xin-Wu Xiao, Xin Su, Yong Song
Bronchioloalveolar carcinoma (BAC) is a unique lung neoplasm with variable forms, such as single nodular, multifocal and lobar pneumonic types. The pneumonic type BAC is often difficult to differentiate from pneumonia. Here we present a case of 63-year-old Chinese male, who had recurrent cough, white sputum with pneumonic lesions in left lower lobe. He suffered from lung biopsies for three times, and finally diagnosed as high differentiated adenocarcinoma 8 years later. He was treated with four cycles of pemetrexed and cisplatin, and four cycles of docetaxel and nedaplatin...
June 2016: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/27335360/congenital-lobar-emphysema-diagnostic-and-therapeutic-challenges
#14
James Jackson Mulvany, Andrew Weatherall, Amanda Charlton, Hiran Selvadurai
Congenital lobar emphysema (CLE), a rare condition that usually presents in the neonatal period, can be a diagnostic and therapeutic challenge for the treating clinician. If unrecognised, it is a significant risk at the time of anaesthetic induction. We describe a case of CLE in a 3-month-old boy who was initially treated for suspected aspiration pneumonia at the referring hospital. We highlight the importance of careful consideration of common childhood respiratory illness as well as pneumothorax in the differential diagnosis, and the significance of appropriate preoperative anaesthetic management...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27319003/outcomes-and-infectious-etiologies-of-febrile-neutropenia-in-non-immunocompromised-children-who-present-in-an-emergency-department
#15
C Pascual, V Trenchs, S Hernández-Bou, A Català, A F Valls, C Luaces
There are no unified protocols governing the management of healthy children with febrile neutropenia in the emergency department (ED). Conservative management is the norm, with admission and empirical broad-spectrum antibiotics prescribed, although viral infections are considered the most frequent etiology. The aim of this study was to describe the clinical outcomes and identified etiologies of unsuspected neutropenia in febrile immunocompetent children assessed in the ED. This was a retrospective study: well-appearing healthy children <18 years old with febrile moderate [absolute neutrophil count (ANC) 500-999 neutrophils ×10(9)/l] or severe (ANC <500 neutrophils ×10(9)/l) neutropenia diagnosed in ED between 2005 and 2013 were included...
October 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27185998/congenital-lobar-emphysema-pitfalls-in-diagnosis
#16
Abhishek Chinya, Prince Raj Pandey, Shandip Kumar Sinha, Yogesh Kumar Sarin
Congenital lobar emphysema (CLE) is a rare but life-threatening congenital anomaly leading to respiratory distress in early childhood. Diagnosis requires a strong clinical suspicion. We report a case of a 31/2-month-old infant who was initially diagnosed with pneumonia requiring multiple hospital admissions. After computed tomography of the thorax, a diagnosis on CLE was made. The child was planned for surgery in the next available routine operation theatre. However, suddenly in the evening, she developed respiratory distress and needed emergency surgical intervention...
May 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27184935/a-case-of-lobar-pneumonia-and-sepsis-with-death-caused-by-invasive-klebsiella-rhinoscleromatis-infection
#17
Eri Kumade, Norihiro Furusyo, Norito Takeshima, Yasuhiro Kishihara, Fujiko Mitsumoto-Kaseida, Yoshitaka Etoh, Masayuki Murata, Jun Hayashi
Klebsiella pneumoniae often causes pneumonia and other infections in heavy drinkers and patients with diabetes. Pneumonia caused by Klebsiella rhinoscleromatis, a subspecies of K. pneumoniae, has not been previously reported. We report a case of pneumonia caused by K. rhinoscleromatis. A 68-year-old man with type 2 diabetes visited our department complaining fever and fatigue for 10 days and cough and bloody sputum for two days. His Japan Coma Scale score was I-1, body temperature 38.3 °C, blood pressure 85/51 mmHg, pulse 135 bpm, and peripheral capillary oxygen saturation level 92% (room air)...
October 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/27165585/-early-predictors-of-necrotizing-pneumonia-in-children
#18
Shuai-Shuai Liu, Li-Jun Song, Fan-Zheng Meng, Li Peng, Yu-Huan Liu
OBJECTIVE: To investigate the early predictors of necrotizing pneumonia in children. METHODS: The clinical data of 43 children with necrotizing pneumonia and 83 children with lobar pneumonia were retrospectively analyzed. Sex, age, the number of days with fever, laboratory examination results, and bronchoscopic findings were compared between the two groups. The multiple logistic regression analysis was used to identify the early predictors of necrotizing pneumonia...
May 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27085876/pulmonary-actinomycosis-presenting-as-post-obstructive-pneumonia
#19
K Kassab, M Karnib, P K Bou-Khalil, A R Bizri
Actinomycosis is a chronic suppurative infection caused by filamentous Gram-positive bacilli, leading to a purulent discharge due to sulfur granule formation. Thoracic actinomycosis represents around 20% of Actinomyces infections, with endobronchial involvement being fairly uncommon. Pulmonary actinomycosis should be considered in the differential diagnosis of non-resolving lobar pneumonia or a lobar mass suspicious for malignancy on endobronchial biopsy. A case of endobronchial actinomycosis presenting as post-obstructive pneumonia and mimicking right upper lobe endobronchial carcinoma, which was associated with foreign body aspiration, is reported here...
July 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27043691/low-serum-fetuin-a-as-a-biomarker-to-predict-pneumococcal-necrotizing-pneumonia-and-hemolytic-uremic-syndrome-in-children
#20
Rajendra Prasad Janapatla, Mei-Hua Hsu, Wan-Ting Liao, Kun-Yi Chien, Hao-Yuan Lee, Cheng-Hsun Chiu
Streptococcus pneumoniae, a neuraminidase-producing pathogen, can cause invasive pneumococcal disease (IPD) with or without hemolytic uremic syndrome (HUS) in humans. We aimed to identify serum sialoglycoproteins that are targeted by neuraminidases in severe pneumococcal infection. We hypothesized that serum sialoglycoprotein such as fetuin-A can serve as a biomarker to predict IPD or HUS. We constructed serum sialoglycoprotein profiles before and after pneumococcal neuraminidase treatment using liquid chromatography-tandem mass spectrometry (LC-MS/MS), a proteomic approach...
March 2016: Medicine (Baltimore)
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