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Quality use of pathology

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https://www.readbyqxmd.com/read/28231390/intraoperative-assessment-of-laryngeal-pathologies-with-optical-coherence-tomography-integrated-into-a-surgical-microscope
#1
Anna S Englhard, Tom Betz, Veronika Volgger, Eva Lankenau, Georg J Ledderose, Herbert Stepp, Christian Homann, Christian S Betz
OBJECTIVE: Endoscopic examination followed by tissue biopsy is the gold standard in the evaluation of lesions of the upper aerodigestive tract. However, it can be difficult to distinguish between healthy mucosa, dysplasia, and invasive carcinoma. Optical coherence tomography (OCT) is a non-invasive technique which acquires high-resolution, cross-sectional images of tissue in vivo. Integrated into a surgical microscope, it allows the intraoperative evaluation of lesions simultaneously with microscopic visualization...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28231320/improved-image-quality-and-diagnostic-potential-using-ultra-high-resolution-computed-tomography-of-the-lung-with-small-scan-fov-a-prospective-study
#2
Huiyuan Zhu, Lian Zhang, Yali Wang, Preeti Hamal, Xiaofang You, Haixia Mao, Fei Li, Xiwen Sun
The aim of this study was to assess whether CT imaging using an ultra-high-resolution CT (UHRCT) scan with a small scan field of view (FOV) provides higher image quality and helps to reduce the follow-up period compared with a conventional high-resolution CT (CHRCT) scan. We identified patients with at least one pulmonary nodule at our hospital from July 2015 to November 2015. CHRCT and UHRCT scans were conducted in all enrolled patients. Three experienced radiologists evaluated the image quality using a 5-point score and made diagnoses...
2017: PloS One
https://www.readbyqxmd.com/read/28229625/is-pain-at-discharge-a-risk-factor-for-unplanned-hospital-readmission
#3
Mieke Deschepper, Peter Vermeir, Dirk Vogelaers, Jacques Devulder, Kristof Eeckloo
INTRODUCTION: Unplanned readmissions are associated with a high cost to health insurances and the incidence of preventable readmissions could be considered as a quality indicator for the initial hospital admission. We aimed to assess the predictive value for unplanned readmission of higher pain scores at discharge of the initial admission as well as of other pain and demographic characteristics. The documentation of significant associations would provide further support for a structured pain management policy...
February 23, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28228347/effect-of-hyaluronic-acid-on-the-regulation-of-inflammatory-mediators-in-osteoarthritis-of-the-temporomandibular-joint-a-systematic-review
#4
REVIEW
V Iturriaga, T Bornhardt, C Manterola, P Brebi
Osteoarthritis is one of the most frequent pathologies affecting the temporomandibular joint (TMJ). There is evidence that the use of intra-articular hyaluronic acid (HA) for the treatment of this disorder achieves positive effects through a reduction in inflammatory mediators. A systematic review of the available evidence regarding the regulation of inflammatory mediators when applying HA in osteoarthritis of the TMJ in humans was performed. The Web of Science, Embase, ScienceDirect, MEDLINE, Scopus, EBSCOhost, and LILACS databases, SciELO library, and search engine Trip Database were searched systematically...
February 19, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28227762/single-shot-turbo-spin-echo-acquisition-for-in-vivo-cardiac-diffusion-mri
#5
Masoud Edalati, Gregory R Lee, Hui Wang, Michael D Taylor, Yu Y Li, Masoud Edalati, Gregory R Lee, Hui Wang, Michael D Taylor, Yu Y Li, Masoud Edalati, Gregory R Lee, Michael D Taylor, Hui Wang, Yu Y Li
Diffusion MRI offers the ability to noninvasively characterize the microstructure of myocardium tissue and detect disease related pathology in cardiovascular examination. This study investigates the feasibility of in vivo cardiac diffusion MRI under free-breathing condition. A high-speed imaging technique, correlation imaging, is used to enable single-shot turbo spin echo for free-breathing cardiac data acquisition. The obtained in vivo cardiac diffusion-weighted images illustrate robust image quality and minor geometry distortions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227729/high-frame-rate-medical-quality-video-compression-for-tele-eeg
#6
Laurent Lambert, Syed Zahid Ahmed, Khalil Hachicha, Andrea Pinna, Patrick Garda, Laurent Lambert, Syed Zahid Ahmed, Khalil Hachicha, Andrea Pinna, Patrick Garda, Syed Zahid Ahmed, Andrea Pinna, Laurent Lambert, Patrick Garda, Khalil Hachicha
More and more, exams require medical images as a tool to diagnose pathologies. Thus, the transfer and storage of the exam data becomes a critical issue. To address this issue, an image compression algorithm called Waaves has been developed and certified for medical imaging. Our work in this paper deals with a scenario of EEG exams where video of the patient is also recorded in order to correctly diagnose myoclonus pathologies. To achieve this goal, the video needs to be of high quality and at frame rate of at least 100 frames per second...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227360/unsupervised-abnormality-detection-using-saliency-and-retinex-based-color-enhancement
#7
Farah Deeba, Shahed K Mohammed, Francis M Bui, Khan A Wahid, Farah Deeba, Shahed K Mohammed, Francis M Bui, Khan A Wahid, Shahed K Mohammed, Francis M Bui, Khan A Wahid, Farah Deeba
An efficient and automated abnormality detection method can significantly reduce the burden of screening of the enormous visual information resulting from capsule endoscopic procedure. As a pre-processing stage, color enhancement could be useful to improve the image quality and the detection performance. Therefore, in this paper, we have proposed a two-stage automated abnormality detection algorithm. In the first stage, an adaptive color enhancement method based on Retinex theory is applied on the endoscopic images...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227154/teaching-cardiopulmonary-auscultation-in-workshops-using-a-virtual-patient-simulation-technology-a-pilot-study
#8
D Pereira, P Gomes, S Faria, R Cruz-Correia, M Coimbra, D Pereira, P Gomes, S Faria, R Cruz-Correia, M Coimbra, P Gomes, R Cruz-Correia, S Faria, M Coimbra, D Pereira
Auscultation is currently both a powerful screening tool, providing a cheap and quick initial assessment of a patient's clinical condition, and a hard skill to master. The teaching of auscultation in Universities is today reduced to an unsuitable number of hours. Virtual patient simulators can potentially mitigate this problem, by providing an interesting high-quality alternative to teaching with real patients or patient simulators. In this paper we evaluate the pedagogical impact of using a virtual patient simulation technology in a short workshop format for medical students, training them to detect cardiac pathologies...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224029/designing-clinical-and-genetic-guidelines-of-colorectal-cancer-screening-as-an-effective-roadmap-for-risk-management
#9
Mohammad Reza Zali, Reza Safdari, Elham Maserat, Hamid Asadzadeh Aghdaei
AIM: We aimed to present clinical and genetic guidelines of colorectal cancer screening for risk assessment of populations at risk. BACKGROUND: National guidelines can be used as a guide for choosing the method of screening for each individual. These guidelines facilitate decision making and support the delivery of cancer screening service. METHODS: In the first step, a comparative study was performed by using secondary data extracted from the literature review...
December 2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28220804/impact-of-symptomatic-skeletal-events-on-health-care-resource-utilization-and-quality-of-life-among-patients-with-castration-resistant-prostate-cancer-and-bone-metastases
#10
R McKay, B Haider, M S Duh, A Valderrama, M Nakabayashi, M Fiorillo, L Ristovska, L Wen, P Kantoff
BACKGROUND: Data regarding the impact of symptomatic skeletal events (SSEs) on health economics and patient-reported outcomes in men with castration-resistant prostate cancer (CRPC) and bone metastases from a clinical setting are lacking. Hence, this study aimed to quantify the effects of SSEs on health-care resource utilization (HRU), health-related quality of life (HRQoL) and pain in men with CRPC metastasized to bone. METHODS: This cohort study included men with CRPC and bone metastasis treated at a tertiary center during December 1996-July 2015...
February 21, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28216385/the-role-of-mitochondria-in-cardiac-development-and-protection
#11
REVIEW
Jaakko L Pohjoismäki, Steffi Goffart
Mitochondria are essential for the development as well as maintenance of the myocardium, the most energy consuming tissue in the human body. Mitochondria are not only a source of ATP energy but also generators of reactive oxygen species (ROS), that cause oxidative damage, but also regulate physiological processes such as the switch from hyperplastic to hypertrophic growth after birth. As excess ROS production and oxidative damage are associated with cardiac pathology, it is not surprising that much of the research focused on the deleterious aspects of free radicals...
February 16, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28215407/a-simplified-vocal-profile-analysis-protocol-for-the-assessment-of-voice-quality-and-speaker-similarity
#12
Eugenia San Segundo, Jose A Mompean
OBJECTIVES: A simplified perceptual protocol for the assessment of voice quality (VQ) is attempted based on the Vocal Profile Analysis (VPA) scheme, with the aim of alleviating typical issues associated with the multidimensionality of VQ and enabling an easy quantification of speaker similarity. STUDY DESIGN: Twenty-four non-pathological male speakers (12 monozygotic twin pairs) of Standard Peninsular Spanish were perceptually evaluated by two trained phoneticians using the simplified VPA (SVPA)...
February 15, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28210788/surgical-management-of-degenerative-meniscus-lesions-the-2016-esska-meniscus-consensus
#13
Ph Beaufils, R Becker, S Kopf, M Englund, R Verdonk, M Ollivier, R Seil
PURPOSE: A degenerative meniscus lesion is a slowly developing process typically involving a horizontal cleavage in a middle-aged or older person. When the knee is symptomatic, arthroscopic partial meniscectomy has been practised for a long time with many case series reporting improved patient outcomes. Since 2002, several randomised clinical trials demonstrated no additional benefit of arthroscopic partial meniscectomy compared to non-operative treatment, sham surgery or sham arthroscopic partial meniscectomy...
February 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28209159/do-coursework-summative-assessments-predict-clinical-performance-a-systematic-review
#14
Rebecca Terry, Wayne Hing, Robin Orr, Nikki Milne
BACKGROUND: Two goals of summative assessment in health profession education programs are to ensure the robustness of high stakes decisions such as progression and licensing, and predict future performance. This systematic and critical review aims to investigate the ability of specific modes of summative assessment to predict the clinical performance of health profession education students. METHODS: PubMed, CINAHL, SPORTDiscus, ERIC and EMBASE databases were searched using key terms with articles collected subjected to dedicated inclusion criteria...
February 16, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28208056/oral-rehabilitation-of-a-patient-with-ectodermal-dysplasia-treated-with-fresh-frozen-bone-allografts-and-computer-guided-implant-placement-a-clinical-case-report
#15
Carlo Maiorana, Pier Paolo Poli, Carlo Poggio, Paola Barbieri, Mario Beretta
Ectodermal dysplasia (ED) is an inherited disorder characterized by abnormality of ectodermally derived structures. A recurrent oral finding is oligodontia, which in turn leads to a severely hypotrophic alveolar process with typical knife-edge morphology and adverse ridge contours. This unfavorable anatomy can seriously hamper proper implant placement. Fresh-frozen bone (FFB) allografts recently have been proposed to augment the residual bone volume for implant placement purposes; however, scientific evidence concerning the use of FFB to treat ED patients is absent...
January 20, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28196217/pathologic-outcomes-of-laparoscopic-vs-open-mesorectal-excision-for-rectal-cancer-a-systematic-review-and-meta-analysis
#16
Aleix Martínez-Pérez, Maria Clotilde Carra, Francesco Brunetti, Nicola de'Angelis
Importance: Rectal resection with mesorectal excision is the mainstay treatment for rectal cancer. Objective: To review and analyze the evidence concerning the pathologic outcomes of laparoscopic (LRR) vs open (ORR) rectal resection for rectal cancer. Data Sources: The Cochrane Central Register of Controlled Trials, MEDLINE (through PubMed), EMBASE, Scopus databases, and clinicaltrials.gov were searched for randomized clinical trials (RCTs) comparing LRR vs ORR...
February 8, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28195993/subcutaneous-testosterone-letrozole-therapy-before-and-concurrent-with-neoadjuvant-breast-chemotherapy-clinical-response-and-therapeutic-implications
#17
Rebecca L Glaser, Anne E York, Constantine Dimitrakakis
OBJECTIVE: Hormone receptor-positive breast cancers respond favorably to subcutaneous testosterone combined with an aromatase inhibitor. However, the effect of testosterone combined with an aromatase inhibitor on tumor response to chemotherapy was unknown. This study investigated the effect of testosterone-letrozole implants on breast cancer tumor response before and during neoadjuvant chemotherapy. METHODS: A 51-year-old woman on testosterone replacement therapy was diagnosed with hormone receptor-positive invasive breast cancer...
February 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28195621/histopathologic-analysis-of-the-posterior-segment-for-terson-s-syndrome-the-giobiopsy-technique
#18
Jerome V Giovinazzo, Vincent J Giovinazzo, Codrin Iacob, Richard B Rosen, Paul T Finger
The purpose of this study was to report on a case of Terson's syndrome (TS) using a novel instrument and technique to harvest posterior pole pathology from a postmortem eye. A modified ocular clamp was used to remove the posterior pole from the postmortem enucleated eye. Gross photographs were taken and an ocular sample of the posterior pole was sent to The New York Eye and Ear Pathology Laboratory. TS was identified from gross pathology and histologic examinations. The case history was consistent with that diagnosis...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28190674/neuronal-loss-and-%C3%AE-synuclein-pathology-in-the-superior-colliculus-and-its-relationship-to-visual-hallucinations-in-dementia-with-lewy-bodies
#19
Daniel Erskine, Alan J Thomas, John-Paul Taylor, Michael A Savage, Johannes Attems, Ian G McKeith, Christopher M Morris, Ahmad A Khundakar
OBJECTIVE: Patients with dementia with Lewy bodies (DLB) often experience visual hallucinations, which are related to decreased quality of life for patients and increased caregiver distress. The pathologic changes that contribute to visual hallucinations are not known, but several hypotheses implicate deficient attentional processing. The superior colliculus has a role in visual attention and planning eye movements and has been directly implicated in several models of visual hallucinations...
January 10, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28187030/evolution-of-quality-assurance-for-clinical-immunohistochemistry-in-the-era-of-precision-medicine-part-3-technical-validation-of-immunohistochemistry-ihc-assays-in-clinical-ihc-laboratories
#20
Emina E Torlakovic, Carol C Cheung, Corrado D'Arrigo, Manfred Dietel, Glenn D Francis, C Blake Gilks, Jacqueline A Hall, Jason L Hornick, Merdol Ibrahim, Antonio Marchetti, Keith Miller, J Han van Krieken, Soren Nielsen, Paul E Swanson, Mogens Vyberg, Xiaoge Zhou, Clive R Taylor
Validation of immunohistochemistry (IHC) assays is a subject that is of great importance to clinical practice as well as basic research and clinical trials. When applied to clinical practice and focused on patient safety, validation of IHC assays creates objective evidence that IHC assays used for patient care are "fit-for-purpose." Validation of IHC assays needs to be properly informed by and modeled to assess the purpose of the IHC assay, which will further determine what sphere of validation is required, as well as the scope, type, and tier of technical validation...
February 9, 2017: Applied Immunohistochemistry & Molecular Morphology: AIMM
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