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https://www.readbyqxmd.com/read/28721511/molecular-and-phylogenetic-characterization-of-bovine-coronavirus-virus-isolated-from-dairy-cattle-in-central-region-thailand
#1
Kanokwan Singasa, Taweesak Songserm, Preeda Lertwatcharasarakul, Pipat Arunvipas
Bovine coronavirus (BCoV) is involved mainly in enteric infections in cattle. This study reports the first molecular detection of BCoV in a diarrhea outbreak in dairy cows in the Central Region, Thailand. BCoV was molecularly detected from bloody diarrheic cattle feces by using nested PCR. Agarose gel electrophoresis of three diarrheic fecal samples yielded from the 25 samples desired amplicons that were 488 base pairs and sequencing substantiated that have BCoV. The sequence alignment indicated that nucleotide and amino acid sequences, the three TWD isolated in Thailand, were more quite homologous to each other (amino acid at position 39 of TWD1, TWD3 was proline, but TWD2 was serine) and closely related to OK-0514-3strain (virulent respiratory strain; RBCoV)...
July 18, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28708077/environmental-drivers-and-predicted-risk-of-bacillary-dysentery-in-southwest-china
#2
Han Zhang, Yali Si, Xiaofeng Wang, Peng Gong
Bacillary dysentery has long been a considerable health problem in southwest China, however, the quantitative relationship between anthropogenic and physical environmental factors and the disease is not fully understand. It is also not clear where exactly the bacillary dysentery risk is potentially high. Based on the result of hotspot analysis, we generated training samples to build a spatial distribution model. Univariate analyses, autocorrelation and multi-collinearity examinations and stepwise selection were then applied to screen the potential causative factors...
July 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28706469/metabolic-response-of-porcine-colon-explants-to-in-vitro-infection-by-brachyspira-hyodysenteriae-a-leap-into-disease-pathophysiology
#3
Thijs Welle, Anna T Hoekstra, Ineke A J J M Daemen, Celia R Berkers, Matheus O Costa
INTRODUCTION: Swine dysentery caused by Brachyspira hyodysenteriae is a production limiting disease in pig farming. Currently antimicrobial therapy is the only treatment and control method available. OBJECTIVE: The aim of this study was to characterize the metabolic response of porcine colon explants to infection by B. hyodysenteriae. METHODS: Porcine colon explants exposed to B. hyodysenteriae were analyzed for histopathological, metabolic and pro-inflammatory gene expression changes...
2017: Metabolomics: Official Journal of the Metabolomic Society
https://www.readbyqxmd.com/read/28694749/variability-of-antioxidant-and-biological-activities-of-rhus-tripartitum-related-to-phenolic-compounds
#4
Hanène Ben Miled, Mariem Saada, Ines Jallali, Zaineb Ben Barka, Mounira Tlili, Hichem Alimi, Mohsen Sakly, Khémais Ben Rhouma, Manef Abderrabba, Hafedh Abdelmelek, Olfa Tebourbi, Riadh Ksouri
Rhus species are known in traditional medicine for their therapeutic virtue and their extracts showed numerous important properties including antimalarial, antimicrobial, antiviral, and hypoglycemic and anticonvulsant activities. Rhus tripartitum (Ucria) is a medicinal plant widely used in Tunisia folk medicine against chronic diarrhea and gastric ulcer. This study was designed to examine in vitro and ex vivo antioxidant, anti-inflammatory and anticancer activities of four extracts of Rhus tripartitum root cortex with increasing solvent polarity (hexane, dichloromethane, methanol and water)...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28687951/approach-to-upset-stomach
#5
Rishi Bolia
An "Upset stomach" is a common problem encountered by physicians involved in the care of children. It includes, diarrhea, vomiting or abdominal pain. Though often mild and self-limiting, at times there are uncommon life-threatening conditions that require urgent care. It is important for primary physicians to recognize "alarm signs" and make a referral to the specialist at the right time. At the same time it is important to recognize what is normal and re-assure the caregivers. A detailed history and a proper systemic examination are important at presentation, looking for any "red flags"...
July 8, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28671329/suppression-of-il-8-release-by-sweet-olive-ethanolic-extract-and-compounds-in-widr-colon-adenocarcinoma-cells
#6
Yi-Ling Ye, Huei-Shin Chang, Yu-Fang Tseng, Li-Shian Shi
Oxidative stress can stimulate the secretion of pro-inflammatory cytokines. Interleukin-8 (IL-8) has been implicated in the pathogenesis of inflammatory bowel disease and the metastatic spread of colorectal cancer. The flowers of Osmanthus fragrans (sweet olive) are used to alleviate dysentery with blood in the bowel, as well as stomach ache and diarrhea. However, the evidence of their therapeutic effects on these symptoms remains unclear. In the present study, the protective effects of sweet olive flower ethanolic extract (OFE) against oxidative stress in WiDr cells was assessed by evaluating its 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity...
July 3, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28659988/systems-pharmacological-approach-of-pulsatillae-radix-on-treating-crohn-s-disease
#7
Su Yeon Suh, Won G An
In East Asian traditional medicine, Pulsatillae Radix (PR) is widely used to treat amoebic dysentery and renowned for its anti-inflammatory effects. This study aimed to confirm evidence regarding the potential therapeutic effect of PR on Crohn's disease using a system network level based in silico approach. Study results showed that the compounds in PR are highly connected to Crohn's disease related pathways, biological processes, and organs, and these findings were confirmed by compound-target network, target-pathway network, and gene ontology analysis...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28651094/in-vitro-susceptibility-of-brachyspira-hyodysenteriae-to-a-commercial-citrus-fruit-extract
#8
Pedro J G de Nova, Ana Carvajal, Miguel Prieto, Pedro Rubio
Brachyspira hyodysenteriae is the main etiological agent of swine dysentery (SD). Nowadays, treatment and control of SD is increasingly difficult due to the emergence of antimicrobial resistance together with the restrictions on the use of antibiotics in veterinary practice. The aim of this study was to evaluate, as an alternative in the control of this disease, the antimicrobial activity and the main mechanism of action of BIOCITRO, a citrus extract commercialized as raw material and used as feed additive, against B...
June 20, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28649416/educational-intervention-to-reduce-disease-related-to-sub-optimal-basic-hygiene-in-rwanda-initial-evaluation-and-feasibility-study
#9
Margaret A Stone, Hormisdas Ndagijimana
BACKGROUND: Despite a global reduction in morbidity related to sub-optimal water, sanitation and hygiene, the incidence of such diseases remains a significant problem in sub-Saharan Africa. This study aimed to initially assess the potential effectiveness (primarily in terms of impact on morbidity) of a simple educational intervention delivered in Rwanda. Additionally, we sought to explore feasibility relating to the practicality of evaluating and implementing this type of intervention in a low- and middle-income country...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28638879/traditional-knowledge-of-medicinal-plants-in-tribes-of-tripura-in-northeast-india
#10
Maria Debbarma, Nazir A Pala, Munesh Kumar, Rainer W Bussmann
BACKGROUND: The present study was carried out in Mandwi area and its outskirts of Tripura district of tribal areas Autonomous district council to document the available ethno-medicinal plants and their traditional application among Mandwi tribes. METHODOLOGY: Field explorations were carried out during the months of March-June 2013. The ethno-medicinal survey was conducted particularly with Tripuri tribe in Mandai area, with the help of local medicine men, locally known as bhoidho (Tripuri)...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28637484/seasonal-and-geographical-distribution-of-bacillary-dysentery-shigellosis-and-associated-climate-risk-factors-in-kon-tam-province-in-vietnam-from-1999-to-2013
#11
Hu Suk Lee, T T Ha Hoang, Phuc Pham-Duc, Mihye Lee, Delia Grace, Dac Cam Phung, Vu Minh Thuc, Hung Nguyen-Viet
BACKGROUND: Bacillary dysentery (BD) is an acute bacterial infection of the intestine caused by Shigella spp., with clinical symptoms ranging from fever to bloody diarrhoea to abdominal cramps to tenesmus. In Vietnam, enteric bacterial pathogens are an important cause of diarrhoea and most cases in children under 5 years of age are due to Shigella strains. The serogroups S. flexneri and S. sonnei are considered to be the most common. The main objective of this study was to, for the first time, assess the seasonal patterns and geographic distribution of BD in Vietnam, and to determine the climate risk factors associated with the incidence of BD in Kon Tum Province, where the highest rate of bacillary dysentery was observed from 1999 to 2013...
June 21, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28635648/deoxyelephantopin-and-isodeoxyelephantopin-as-potential-anticancer-agents-with-effects-on-multiple-signaling-pathways
#12
REVIEW
Tahir Mehmood, Amara Maryam, Hamed A Ghramh, Muhammad Khan, Tonghui Ma
Cancer is the 2nd leading cause of death worldwide. The development of drugs to target only one specific signaling pathway has limited therapeutic success. Developing chemotherapeutics to target multiple signaling pathways has emerged as a new prototype for cancer treatment. Deoxyelephantopin (DET) and isodeoxyelephantopin (IDET) are sesquiterpene lactone components of "Elephantopus scaber and Elephantopus carolinianus", traditional Chinese medicinal herbs that have long been used as folk medicines to treat liver diseases, diabetes, diuresis, bronchitis, fever, diarrhea, dysentery, cancer, and inflammation...
June 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28629185/leptadenia-reticulata-retz-wight-arn-jivanti-botanical-agronomical-phytochemical-pharmacological-and-biotechnological-aspects
#13
REVIEW
Sudipta Kumar Mohanty, Mallappa Kumara Swamy, Uma Rani Sinniah, Maniyam Anuradha
Leptadenia reticulata (Retz.) Wight & Arn. (Apocynaceae), is a traditional medicinal plant species widely used to treat various ailments such as tuberculosis, hematopoiesis, emaciation, cough, dyspnea, fever, burning sensation, night blindness, cancer, and dysentery. In Ayurveda, it is known for its revitalizing, rejuvenating, and lactogenic properties. This plant is one of the major ingredients in many commercial herbal formulations, including Speman, Envirocare, Calshakti, Antisept, and Chyawanprash. The therapeutic potential of this herb is because of the presence of diverse bioactive compounds such as α-amyrin, β-amyrin, ferulic acid, luteolin, diosmetin, rutin, β-sitosterol, stigmasterol, hentricontanol, a triterpene alcohol simiarenol, apigenin, reticulin, deniculatin, and leptaculatin...
June 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28621111/antiamoebic-activity-of-petiveria-alliacea-leaves-and-their-main-component-isoarborinol
#14
Lizeth Zavala Ocampo, Eva Aguirre HernÁndez, Nury Pérez HernÁndez, Gildardo Rivera SÁnchez, Laurence A Marchat, Esther Ramírez Moreno
Petiveria alliacea L. (Phytolacaceae) is a medicinal plant with a broad range of traditional therapeutic properties, including the treatment of dysentery and intestinal infections caused by protozoan parasites. However its effects against Entamoeba histolytica have not been reported yet. We here investigated the antiamoebic activity present in the leaves of P. alliacea L. Antiamoebic activity was evaluated in methanolic and aqueous extract, as well as in the hexanic, methanolic and EtOAc fractions. P. alliacea L...
June 16, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28618272/shigella-sonnei-encodes-a-functional-t6ss-used-for-interbacterial-competition-and-niche-occupancy
#15
Mark C Anderson, Pascale Vonaesch, Azadeh Saffarian, Benoit S Marteyn, Philippe J Sansonetti
Shigella is a leading cause of dysentery worldwide, with the majority of infections caused by two subgroups, S. flexneri and S. sonnei. Although S. flexneri has been highly prevalent in low-income countries, global development has brought an increase in S. sonnei at the expense of S. flexneri. However, the mechanisms behind this shift are not understood. Here we report that S. sonnei, but not S. flexneri, encodes a type VI secretion system (T6SS) that provides a competitive advantage in the gut. S. sonnei competes against E...
June 14, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28611956/comparative-genomic-and-phylogenetic-analysis-of-a-shiga-toxin-producing-shigella-sonnei-stss-strain
#16
Domonkos Sváb, Balázs Bálint, Bálint Vásárhelyi, Gergely Maróti, István Tóth
Shigella strains are important agents of bacillary dysentery, and in recent years Shigella sonnei has emerged as the leading cause of shigellosis in industrialized and rapidly developing countries. More recently, several S. sonnei and Shigella flexneri strains producing Shiga toxin (Stx) have been reported from sporadic cases and from an outbreak in America. In the present study we aimed to shed light on the evolution of a recently identified Shiga toxin producing S. sonnei (STSS) isolated in Europe. Here we report the first completely assembled whole genome sequence of a multidrug resistant (MDR) Stx-producing S...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28609838/hepatoprotective-mechanism-of-lygodium-microphyllum-cav-r-br-through-ultrastructural-signaling-prevention-against-carbon-tetrachloride-ccl4-mediated-oxidative-stress
#17
Charles Gnanaraj, Muhammad Dawood Shah, Tan Tek Song, Mohammad Iqbal
Plants have been consumed in medicinal practices for centuries. Lygodium microphyllum (Cav.) R.Br. (Lygodiaceae), also known as Old World Climbing Fern, is a medicinal plant used by local communities in Sabah for skin and dysentery ailments. This study aims to test aqueous extract of L. microphyllum leaves for hepatoprotective and immunosuppressive activity in rats. Animal studies were carried out to evaluate hepatoprotection of aqueous extract of L. microphyllum at different doses (200, 400 and 600mg/kg b...
August 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28605848/projected-burden-of-disease-for-bacillary-dysentery-due-to-flood-events-in-guangxi-china
#18
Xuena Liu, Zhidong Liu, Guoyong Ding, Baofa Jiang
Many researchers have been studying the influence of floods on intestinal infection in recent years. This study aimed to project the future disease burden of bacillary dysentery associated with floods in Guangxi, China. Relying on the longitudinal data, a generalized additive mixed model was applied to quantify the relationship between the monthly morbidity of bacillary dysentery and floods with two severity levels from 2004 to 2010, controlling for other meteorological variables. Years Lived with Disability (YLDs) was used as the measure of the burden of bacillary dysentery in the future of Guangxi, China...
June 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28601443/a-cohort-study-of-the-effect-of-winter-dysentery-on-herd-level-milk-production
#19
Ingrid Toftaker, Ingrid Holmøy, Ane Nødtvedt, Olav Østerås, Maria Stokstad
Winter dysentery (WD) is a contagious disease caused by bovine coronavirus. It is characterized by acute onset of diarrhea, fever, depression, and reduced milk yield in adult cattle. Although production loss is a well-known consequence of WD, large-scale studies estimating the effect on milk production are lacking. The objective of this study was to estimate the effect of farmer-reported WD on herd-level milk production and milk composition. A cohort study was performed based on reports of herd outbreaks of winter dysentery during a regional epidemic in Norway during the winter of 2011-2012...
June 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28595500/the-genus-patrinia-a-review-of-traditional-uses-phytochemical-and-pharmacological-studies
#20
Xirui He, Fei Luan, Zefeng Zhao, Ning Ning, Maoxing Li, Ling Jin, Yu Chang, Qiang Zhang, Ni Wu, Linhong Huang
The aim of the present review is to comprehensively outline the botanical description, traditional uses, phytochemistry, pharmacology and toxicology of Patrinia, and to discuss possible trends for the further study of medicinal plants from the genus Patrinia. The genus Patrinia plays an important role in Asian medicine for the treatment of erysipelas, conjunctival congestion with swelling and pain, peri-appendicular abscesses, lung carbuncle, dysentery, leucorrhea, and postpartum disease. More than 210 chemical constituents have been isolated and identified from Patrinia plants, especially P...
2017: American Journal of Chinese Medicine
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