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Ivan Z Nenadic, Bo Qiang, Matthew W Urban, Heng Zhao, William Sanchez, James F Greenleaf, Shigao Chen
Ultrasound and magnetic resonance elastography techniques are used to assess mechanical properties of soft tissues. Tissue stiffness is related to various pathologies such as fibrosis, loss of compliance, and cancer. One way to perform elastography is measuring shear wave velocity of propagating waves in tissue induced by intrinsic motion or an external source of vibration, and relating the shear wave velocity to tissue elasticity. All tissues are inherently viscoelastic and ignoring viscosity biases the velocity-based estimates of elasticity and ignores a potentially important parameter of tissue health...
December 21, 2016: Physics in Medicine and Biology
Mireen Friedrich-Rust, Fabian Schoelzel, Sven Linzbach, Joerg Bojunga, Stefan Zeuzem, Florian Seeger
BACKGROUND: At present the use of transient elastography (TE) in patients with pacemaker (PM) or implantable cardioverter defibrillator (ICD) devices is not recommended, since the safety due to the electromagnet embarked in the vibrator for producing the shearwave has not been evaluated. However, no adverse events of sonographic examinations in this patient group have been reported. AIMS: The aim of the present study was to evaluate the safety of TE in patients with PM or ICD...
November 17, 2016: Digestive and Liver Disease
Haoming Lin, Yuanyuan Shen, Xin Chen, Ying Zhu, Yi Zheng, Xinyu Zhang, Yanrong Guo, Tianfu Wang, Siping Chen
BACKGROUND: Ultrasound elastography has been widely used to measure liver stiffness. However, the accuracy of liver viscoelasticity obtained by ultrasound elastography has not been well established. OBJECTIVE: To assess the accuracy of ultrasound elastography for measuring liver viscoelasticity and compare to conventional rheometry methods. In addition, to determine if combining these two methods could delineate the rheological behavior of liver over a wide range of frequencies...
November 14, 2016: Biorheology
Haoming Lin, Xinyu Zhang, Yuanyuan Shen, Yi Zheng, Yanrong Guo, Ying Zhu, Xianfen Diao, Tianfu Wang, Siping Chen, Xin Chen
This study assesses gradations of hepatic fibrosis in rat livers using both model-dependent and model-independent approaches. Liver fibrosis was induced in 37 rats using carbon tetrachloride (CCl4); 6 rats served as the controls. Shear wave velocity as a function of frequency, referred to as velocity dispersion, was measured in vitro by an ultrasound elastography method called shearwave dispersion ultrasound vibrometry (SDUV). For the model-dependent approach, the velocity dispersion data were fit to the Voigt model to solve the viscoelastic modulus...
January 2017: Medical Engineering & Physics
Shuling Chen, Bing Liao, Zhihai Zhong, Yanling Zheng, Baoxian Liu, Quanyuan Shan, Xiaoyan Xie, Luyao Zhou
To explore an effective noninvasive tool for monitoring liver fibrosis of children with biliary atresia (BA) is important but evidences are limited. This study is to investigate the predictive accuracy of supersonic shearwave elastography (SSWE) in liver fibrosis for postoperative patients with BA and to compare it with aspartate aminotransferase to platelet ratio index (APRI) and fibrosis-4 (FIB-4). 24 patients with BA received SSWE and laboratory tests before scheduled for liver biopsy. Spearman rank coefficient and receiver operating characteristic (ROC) were used to analyze data...
2016: Scientific Reports
X-H Qiao, J-J Zhang, F Gao, F Li, M Bai, L-F Du, J-F Xing
The purpose of this study was to explore the value of two-dimensional ShearWave(™) Elastography (2D-SWE) on quantitatively evaluating the change of the content of collagen fibres in penis. Twenty male Sprague Dawley rats were divided into the pre-sexual maturity group (Group 1) and the sexual decline group (Group 2) according to age. The ultrafast ultrasound device Aixplorer(®) (SuperSonic Imagine, Aix-en-Provence, France) was used for 2D-SWE imaging of penis, and the measurement index was shear wave stiffness (SWS)...
July 12, 2016: Andrologia
E Quarello, R Lacoste, J Mancini, S Melot-Dusseau, G Gorincour
PURPOSE: The purpose of this study was to evaluate the feasibility and reproducibility of transabdominal ShearWave elastography of fetal lungs in pregnant baboons. MATERIALS AND METHODS: During a 9-month period (03/2013-12/2013), two operators prospectively performed ultrasound examinations of fetal lung in pregnant baboons in a primate research center. Evaluation of fetal lungs was first performed in B mode. The ShearWave elastography mode was then activated. Three elasticity measurements were performed by each operator for each lung...
June 2016: Diagnostic and Interventional Imaging
Wei Lin Ng, Kartini Rahmat, Farhana Fadzli, Faizatul Izza Rozalli, Mohammad Nazri Mohd-Shah, Patricia Ann Chandran, Caroline Judy Westerhout, Anushya Vijayananthan, Yang Faridah Abdul Aziz
The purpose of this study was to investigate the diagnostic efficacy of shearwave elastography (SWE) in differentiating between benign and malignant breast lesions.One hundred and fifty-nine lesions were assessed using B-mode ultrasound (US) and SWE parameters were recorded (Emax, Emean, Emin, Eratio, SD). SWE measurements were then correlated with histopathological diagnosis.The final sample contained 85 benign and 74 malignant lesions. The maximum stiffness (Emax) with a cutoff point of ≥ 56.0 kPa (based on ROC curves) provided sensitivity of 100...
March 2016: Medicine (Baltimore)
Pierre Joanne, Maria Kitsara, Solène-Emmanuelle Boitard, Hany Naemetalla, Valérie Vanneaux, Mathieu Pernot, Jérôme Larghero, Patricia Forest, Yong Chen, Philippe Menasché, Onnik Agbulut
Limited data are available on the effects of stem cells in non-ischemic dilated cardiomyopathy (DCM). Since the diffuse nature of the disease calls for a broad distribution of cells, this study investigated the scaffold-based delivery of human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) in a mouse model of DCM. Nanofibrous scaffolds were produced using a clinical grade atelocollagen which was electrospun and cross-linked under different conditions. As assessed by scanning electron microscopy and shearwave elastography, the optimum crosslinking conditions for hiPS-CM colonization proved to be a 10% concentration of citric acid crosslinking agent and 150 min of post-electrospinning baking...
February 2016: Biomaterials
Jan Keller, Tanja Eva-Maria Kaltenbach, Mark Martin Haenle, Suemeyra Oeztuerk, Tilmann Graeter, Richard Andrew Mason, Thomas Seufferlein, Wolfgang Kratzer
BACKGROUND: Objective of the study was to evaluate the diagnostic value of novel ultrasonographic modalities in comparison with simultaneously performed liver biopsy. METHODS: The results of simultaneously performed examinations using Acoustic Structure Quantification (ASQ), Virtual Touch Imaging and Quantification (VTIQ) and Virtual Touch Tissue Quantification (VTTQ) were compared with the findings of liver biopsy in patients with a wide variety of diffuse hepatopathies (n = 51)...
December 3, 2015: BMC Medical Imaging
A C L Lam, S W A Pang, A T Ahuja, K S S Bhatia
OBJECTIVES: To investigate the influence of variations in resting pressure (precompression) on thyroid ultrasound supersonic shear wave elastography (SWE). METHODS: Thirty-five normal thyroid glands (Norm), 55 benign hyperplastic nodules (BHN), and 17 papillary thyroid cancers (PTC) in 96 subjects underwent thyroid SWE. Four precompression levels were applied manually by the operator, ranging from A (baseline, 0 % strain) to D (high, 22-30 % strain). SWE results at each precompression level were compared using ANOVA tests with P < 0...
August 2016: European Radiology
Aymeric Guibal
No abstract text is available yet for this article.
July 2015: Radiology Management
Edwin Quarello, Romain Lacoste, Julien Mancini, Sandrine Melot-Dusseau, Guillaume Gorincour
OBJECTIVES: The purpose of this study was to assess the feasibility and reproducibility of transabdominal ShearWave(TM) elastography of fetal organs in pregnant baboons. MATERIALS AND METHODS: Fetal ultrasounds of all pregnant baboons in a single primate research center were performed prospectively during 9 months. The visualization of fetal targeted organs (liver, proximal and distal lungs, brain white matter and periventricular gray matter) was initially performed using 2D ultrasound, and then elastography mode was activated...
November 2015: Prenatal Diagnosis
Z J Zhang, G Y F Ng, S N Fu
PURPOSE: Tendon mechanical properties are linked to sports performance and tendon-related injuries, such as tendinopathy. Whether habitual loading, such as participation in regular jumping activities, would induce adaptation on tendon mechanical properties remains unclear. METHOD: Forty healthy subjects (10 sedentary, 15 volleyball players, and 15 basketball players) aged between 18 and 35 years were recruited. Supersonic shearwave imaging was used to measure the shear elastic modulus and thickness and cross-sectional area (CSA) of the proximal patellar tendons of both knees at 30° of flexion...
November 2015: European Journal of Applied Physiology
Nan Li, Yu-kun Luo, Wen-bo Tang
OBJECTIVE: To explore the difference between acoustic radiation force impulse (ARFI) and two-dimensional shearwave elastography (2D-SWE) in grading liver fibrosis (LF). METHODS: Sixty New Zealand rabbits were divided into control group (n=10; without any treatment) and LF group (n=50; treated with CCl4 to induce LF at different degrees). Liver stiffness (LS) were measured in all the animals using ARFI and 2D-SWE, and liver tissues in the same sites were collected for pathological analysis...
April 2015: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
Fahrettin Kılıç, Yasemin Kayadibi, Pinar Kocael, Mehmet Velidedeoglu, Ahmet Bas, Selim Bakan, Fatih Aydogan, Adem Karatas, Mehmet Halit Yılmaz
OBJECTIVE: Shear-wave elastography (SWE) presents quantitative data that thought to represent intrinsic features of the target tissue. Factors affecting the metabolism of the breast parenchyma as well as age, menstrual cycle, hormone levels, pregnancy and lactation, pre-compression artifact during the examination could affect these elastic intrinsic features. Aim of our study is to determine variation of fibroadenoma elasticity during the menstrual cycle (MC) by means of real-time shear-wave elastography (SWE) and identify the optimal time for SWE evaluation...
June 2015: European Journal of Radiology
E Quarello, R Lacoste, J Mancini, S Melot-Dusseau, G Gorincour
OBJECTIVES: To evaluate tissue characteristics of the placenta by transabdominal ShearWave Elastography in pregnant baboon. MATERIALS AND METHOD: For 9 months (03/2013-12/2013) two operators (EQ, GG) performed ultrasound of the placenta during pregnancy pregnant baboons station partner primatology project. The identification of the placenta was performed previously in 2D ultrasound. The elastography method was then activated. Three measurements were carried out by operator for each placenta...
March 2015: Gynécologie, Obstétrique & Fertilité
Sung Ii Hwang, Hak Jong Lee
Prostate cancer is one of the most common neoplasms in men. Transrectal ultrasound (TRUS)-guided systematic biopsy has a crucial role in the diagnosis of prostate cancer. However, it shows limited value with gray-scale ultrasound alone because only a small number of malignancies are visible on TRUS. Recently, new emerging technologies in TRUS-guided prostate biopsy were introduced and showed high potential in the diagnosis of prostate cancer. High echogenicity of ultrasound contrast agent reflect the increased status of angiogenesis in tumor...
December 2014: Prostate International
Congzhi Wang, Bo Zeng, Weibao Qiu, Hairong Zheng
Acoustic radiation force impulse (ARFI) technique is a quantitative method for tissue stiffness assessment. It has been proved to be less operator dependent than the quasi-static elastography, and has more simple hardware architecture than the supersonic shearwave imaging (SSI) technique, which make it easier to be miniaturized for some special clinical applications. However, unlike the SSI, ARFI cannot provide real-time 2D images of tissue stiffness distribution mainly due to its data-intensive and time-consuming algorithms...
2014: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Ahmet Bas, Cesur Samanci, Fatih Gulsen, Murat Cantasdemir, Levent Kabasakal, Fatih Kantarci, Furuzan Numan
PURPOSE: To evaluate the effect of ShearWave(™) elastography (SWE) for the assessment of liver fibrosis after radioembolization (RE) in patients with liver malignancies. MATERIALS AND METHODS: We prospectively examined the effects of SWE before and after RE in 17 adult patients, from June 2012 to September 2013. All patients underwent SWE within 1 month before and 3 months (96.3 ± 22.9 days) after RE. Measurements were taken in segments III, IV, V, and VI (lateral/medial left lobe and anterior/posterior right lobe, respectively)...
August 2015: Cardiovascular and Interventional Radiology
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