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Yu-Mee Sohn, Mirinae Seo
PURPOSE: To compare breast stiffness based on shear-wave elastography (SWE) quantitative parameters with histopathologic results diagnosed by ultrasound (US)-guided core needle biopsy (CNB) to determine their association with upgrade rates after surgical excision or follow-up US as well as clinico-radiologic differences between upgrade and non-upgrade groups. MATERIALS AND METHODS: This retrospective study enrolled 225 breast lesions from 225 patients, including 159 benign lesions, 38 high risk lesions and 28 ductal carcinoma in situ (DCIS) diagnosed by US-guided CNB...
March 3, 2018: Clinical Imaging
Paolo Borro, Silvana G Dellepiane, Rinaldo Pellicano, Laura Gemme, Sharmila Fagoonee, Gianni Testino
OBJECTIVE: The need for a staging of hepatic fibrosis has become particularly urgent in the last few years in order to start new therapeutic treatments. The objective of this study is to identify ultrasound descriptors and achieve a staging of hepatic fibrosis with non-invasive, rapid and inexpensive methods, both as an alternative and a support to the ultrasound elastography examination. MATERIALS AND METHODS: This study evaluated 196 patients under treatment at the Alcohological Regional Center...
February 13, 2018: Panminerva Medica
C R C Fontenelle, P Mannarino, F B D O Ribeiro, M A Milito, A C P Carvalho, L L Menegaldo, L F Oliveira
PURPOSE: Shear modulus (μ) is directly correlated to the tissue stiffness and can predict the tendon ultimate force to failure. With the knee extended 0° (K0), semitendinosus tendon (ST) is tensioned while patellar tendon (PT) is relaxed. At 80o , knee flexion (K80) tendons present an opposite stress pattern; however, the relation between ST and PT μ in both situations was not studied yet. METHOD: We accessed the μ of the ST and PT at 0o and 80o knee flexion by supersonic shear wave imaging (SSI) elastography from 18 healthy males...
February 7, 2018: Clinical Physiology and Functional Imaging
L Elkrief, M Ronot, F Andrade, M Dioguardi Burgio, T Issoufaly, M Zappa, O Roux, J Bissonnette, A Payancé, D Lebrec, C Francoz, O Soubrane, D Valla, F Durand, V Vilgrain, L Castera, P-E Rautou
BACKGROUND: Two algorithms based on sequential measurements of liver and spleen stiffness using two-dimensional shearwave elastography (2D-SWE) have been recently proposed to estimate clinically significant portal hypertension (hepatic venous pressure gradient [HVPG] ≥10 mm Hg) in patients with cirrhosis, with excellent diagnostic accuracy. AIM: To validate externally these algorithms in a large cohort of patients with cirrhosis. METHODS: One hundred and ninety-one patients with stable cirrhosis (Child-Pugh class A 39%, B 29% and C 31%) who underwent liver and spleen stiffness measurements using 2D-SWE at the time of HVPG measurement were included...
March 2018: Alimentary Pharmacology & Therapeutics
Su Joa Ahn, Jeong Min Lee, Won Chang, Sang Min Lee, Hyo-Jin Kang, Hyunkyung Yang, Jeong Hee Yoon, Sae Jin Park, Joon Koo Han
OBJECTIVE: To assess intra- and inter-observer reproducibility of a new point shear wave elastography technique (pSWE, S-Shearwave, Samsung Medison) and compare its accuracy in assessing liver stiffness (LS) with an established pSWE technique (Virtual Touch Quantification, VTQ). MATERIALS AND METHODS: Thirty-three patients were enrolled in this Institutional Review Board-approved prospective study. LS values were measured by VTQ on an Acuson S2000 system (Siemens Healthineer) and S-Shearwave on an RS-80A (Samsung Medison) in the same session, followed by two further S-Shearwave sessions for inter- and intra-observer variation at 8-hour intervals...
November 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
Matthias Gatz, Simone Schrading, Timm Dirrichs, Marcel Betsch, Markus Tingart, Björn Rath, Christiane Kuhl, Valentin Quack
BACKGROUND: Highly operator-based injection therapy with vasosclerosing and anesthetic polidocanol is used for tendinopathies. This pilot-study evaluates the topical application of polidocanol gel. METHODS: Prospective case series. 39 patients with tendinopathies (14 Achilles, 14 patella, 11 wrist extensors) with a symptom duration > 6 months were included. Polidocanol and static stretching were the therapy in the first 2 weeks, while static stretching was continuously performed for 6 months...
January 2017: Muscles, Ligaments and Tendons Journal
P Mannarino, K M M Lima, C R C Fontenelle, T T Matta, B F de Salles, R Simão, L F Oliveira
PURPOSE: Quadriceps strength and patellar tendon (PT) are directly linked and intimately related to daily activities and lower limb function. However, the correlation between knee extension torque (KT) and PT Young's modulus (E) measured directly is still unknown. METHOD: We used supersonic shearwave imaging (SSI) to evaluate the elastic property of PT in healthy young men and analysed its correlation with KT. Twenty-two healthy young males were included and both knees were examined...
July 14, 2017: Clinical Physiology and Functional Imaging
Laure Mathevon, F Michel, S Aubry, R Testa, T Lapole, L F Arnaudeau, B Fernandez, B Parratte, P Calmels
INTRODUCTION: Few data exist on the feasibility and reliability of measuring muscular atrophy in 2 dimensions (2D) by ultrasonography (US) and elasticity with shear wave elastography (SWE) in spastic muscles. METHODS: Fourteen patients with chronic stroke took part in 2 intersession reliability experiments performed with 1-week intervals between sessions. Pennation angle (PA), muscle thickness (MT), and shear elastic modulus (µ) were measured in spastic gastrocnemius medialis (GM) muscles at rest and at maximal passive stretching in paretic and nonparetic legs...
February 2018: Muscle & Nerve
Ivan Z Nenadic, Bo Qiang, Matthew W Urban, Heng Zhao, William Sanchez, James F Greenleaf, Shigao Chen
Ultrasound and magnetic resonance elastography techniques are used to assess mechanical properties of soft tissues. Tissue stiffness is related to various pathologies such as fibrosis, loss of compliance, and cancer. One way to perform elastography is measuring shear wave velocity of propagating waves in tissue induced by intrinsic motion or an external source of vibration, and relating the shear wave velocity to tissue elasticity. All tissues are inherently viscoelastic and ignoring viscosity biases the velocity-based estimates of elasticity and ignores a potentially important parameter of tissue health...
January 21, 2017: Physics in Medicine and Biology
Mireen Friedrich-Rust, Fabian Schoelzel, Sven Linzbach, Joerg Bojunga, Stefan Zeuzem, Florian Seeger
BACKGROUND: At present the use of transient elastography (TE) in patients with pacemaker (PM) or implantable cardioverter defibrillator (ICD) devices is not recommended, since the safety due to the electromagnet embarked in the vibrator for producing the shearwave has not been evaluated. However, no adverse events of sonographic examinations in this patient group have been reported. AIMS: The aim of the present study was to evaluate the safety of TE in patients with PM or ICD...
March 2017: Digestive and Liver Disease
Haoming Lin, Yuanyuan Shen, Xin Chen, Ying Zhu, Yi Zheng, Xinyu Zhang, Yanrong Guo, Tianfu Wang, Siping Chen
BACKGROUND: Ultrasound elastography has been widely used to measure liver stiffness. However, the accuracy of liver viscoelasticity obtained by ultrasound elastography has not been well established. OBJECTIVE: To assess the accuracy of ultrasound elastography for measuring liver viscoelasticity and compare to conventional rheometry methods. In addition, to determine if combining these two methods could delineate the rheological behavior of liver over a wide range of frequencies...
2016: Biorheology
Haoming Lin, Xinyu Zhang, Yuanyuan Shen, Yi Zheng, Yanrong Guo, Ying Zhu, Xianfen Diao, Tianfu Wang, Siping Chen, Xin Chen
This study assesses gradations of hepatic fibrosis in rat livers using both model-dependent and model-independent approaches. Liver fibrosis was induced in 37 rats using carbon tetrachloride (CCl4 ); 6 rats served as the controls. Shear wave velocity as a function of frequency, referred to as velocity dispersion, was measured in vitro by an ultrasound elastography method called shearwave dispersion ultrasound vibrometry (SDUV). For the model-dependent approach, the velocity dispersion data were fit to the Voigt model to solve the viscoelastic modulus...
January 2017: Medical Engineering & Physics
Shuling Chen, Bing Liao, Zhihai Zhong, Yanling Zheng, Baoxian Liu, Quanyuan Shan, Xiaoyan Xie, Luyao Zhou
To explore an effective noninvasive tool for monitoring liver fibrosis of children with biliary atresia (BA) is important but evidences are limited. This study is to investigate the predictive accuracy of supersonic shearwave elastography (SSWE) in liver fibrosis for postoperative patients with BA and to compare it with aspartate aminotransferase to platelet ratio index (APRI) and fibrosis-4 (FIB-4). 24 patients with BA received SSWE and laboratory tests before scheduled for liver biopsy. Spearman rank coefficient and receiver operating characteristic (ROC) were used to analyze data...
2016: Scientific Reports
X-H Qiao, J-J Zhang, F Gao, F Li, M Bai, L-F Du, J-F Xing
The purpose of this study was to explore the value of two-dimensional ShearWave(™) Elastography (2D-SWE) on quantitatively evaluating the change of the content of collagen fibres in penis. Twenty male Sprague Dawley rats were divided into the pre-sexual maturity group (Group 1) and the sexual decline group (Group 2) according to age. The ultrafast ultrasound device Aixplorer(®) (SuperSonic Imagine, Aix-en-Provence, France) was used for 2D-SWE imaging of penis, and the measurement index was shear wave stiffness (SWS)...
June 2017: Andrologia
E Quarello, R Lacoste, J Mancini, S Melot-Dusseau, G Gorincour
PURPOSE: The purpose of this study was to evaluate the feasibility and reproducibility of transabdominal ShearWave elastography of fetal lungs in pregnant baboons. MATERIALS AND METHODS: During a 9-month period (03/2013-12/2013), two operators prospectively performed ultrasound examinations of fetal lung in pregnant baboons in a primate research center. Evaluation of fetal lungs was first performed in B mode. The ShearWave elastography mode was then activated. Three elasticity measurements were performed by each operator for each lung...
June 2016: Diagnostic and Interventional Imaging
Wei Lin Ng, Kartini Rahmat, Farhana Fadzli, Faizatul Izza Rozalli, Mohammad Nazri Mohd-Shah, Patricia Ann Chandran, Caroline Judy Westerhout, Anushya Vijayananthan, Yang Faridah Abdul Aziz
The purpose of this study was to investigate the diagnostic efficacy of shearwave elastography (SWE) in differentiating between benign and malignant breast lesions.One hundred and fifty-nine lesions were assessed using B-mode ultrasound (US) and SWE parameters were recorded (Emax, Emean, Emin, Eratio, SD). SWE measurements were then correlated with histopathological diagnosis.The final sample contained 85 benign and 74 malignant lesions. The maximum stiffness (Emax) with a cutoff point of ≥ 56.0 kPa (based on ROC curves) provided sensitivity of 100...
March 2016: Medicine (Baltimore)
Pierre Joanne, Maria Kitsara, Solène-Emmanuelle Boitard, Hany Naemetalla, Valérie Vanneaux, Mathieu Pernot, Jérôme Larghero, Patricia Forest, Yong Chen, Philippe Menasché, Onnik Agbulut
Limited data are available on the effects of stem cells in non-ischemic dilated cardiomyopathy (DCM). Since the diffuse nature of the disease calls for a broad distribution of cells, this study investigated the scaffold-based delivery of human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) in a mouse model of DCM. Nanofibrous scaffolds were produced using a clinical grade atelocollagen which was electrospun and cross-linked under different conditions. As assessed by scanning electron microscopy and shearwave elastography, the optimum crosslinking conditions for hiPS-CM colonization proved to be a 10% concentration of citric acid crosslinking agent and 150 min of post-electrospinning baking...
February 2016: Biomaterials
Jan Keller, Tanja Eva-Maria Kaltenbach, Mark Martin Haenle, Suemeyra Oeztuerk, Tilmann Graeter, Richard Andrew Mason, Thomas Seufferlein, Wolfgang Kratzer
BACKGROUND: Objective of the study was to evaluate the diagnostic value of novel ultrasonographic modalities in comparison with simultaneously performed liver biopsy. METHODS: The results of simultaneously performed examinations using Acoustic Structure Quantification (ASQ), Virtual Touch Imaging and Quantification (VTIQ) and Virtual Touch Tissue Quantification (VTTQ) were compared with the findings of liver biopsy in patients with a wide variety of diffuse hepatopathies (n = 51)...
December 3, 2015: BMC Medical Imaging
A C L Lam, S W A Pang, A T Ahuja, K S S Bhatia
OBJECTIVES: To investigate the influence of variations in resting pressure (precompression) on thyroid ultrasound supersonic shear wave elastography (SWE). METHODS: Thirty-five normal thyroid glands (Norm), 55 benign hyperplastic nodules (BHN), and 17 papillary thyroid cancers (PTC) in 96 subjects underwent thyroid SWE. Four precompression levels were applied manually by the operator, ranging from A (baseline, 0 % strain) to D (high, 22-30 % strain). SWE results at each precompression level were compared using ANOVA tests with P < 0...
August 2016: European Radiology
Aymeric Guibal
No abstract text is available yet for this article.
July 2015: Radiology Management
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