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Acute decompensated heart failure

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https://www.readbyqxmd.com/read/28069685/associations-of-body-mass-index-with-laboratory-and-biomarkers-in-patients-with-acute-heart-failure
#1
Koen W Streng, Jozine M Ter Maaten, John G Cleland, Christopher M O'Connor, Beth A Davison, Marco Metra, Michael M Givertz, John R Teerlink, Piotr Ponikowski, Daniel M Bloomfield, Howard C Dittrich, Hans L Hillege, Dirk J van Veldhuisen, Adriaan A Voors, Peter van der Meer
BACKGROUND: Plasma concentrations of natriuretic peptides decline with obesity in patients with heart failure. Whether this is true for other biomarkers is unknown. We investigated a wide range of biomarker profiles in acute heart failure across the body mass index (BMI) spectrum. METHODS AND RESULTS: A total of 48 biomarkers, assessing multiple pathophysiological pathways, were measured in 2033 patients included in PROTECT (Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function), a trial comparing the effects of rolofylline to placebo in patients with acute heart failure...
January 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28062350/discordance-of-patient-reported-and-clinician-ordered-resuscitation-status-in-patients-hospitalized-with-acute-decompensated-heart-failure
#2
Kathleen A Young, Sara E Wordingham, Jacob J Strand, Vėronique L Roger, Shannon M Dunlay
CONTEXT: Accurate documentation of preferences for cardiopulmonary resuscitation at hospital admission is critical to ensure that patients receive resuscitation or not in accordance with their wishes. OBJECTIVES: We sought to identify and characterize inconsistencies in patient-reported and clinician-ordered resuscitation status in patients hospitalized with acute decompensated heart failure (ADHF). METHODS: Southeastern Minnesota residents hospitalized with ADHF were prospectively enrolled into a study that included the administration of face-to-face questionnaires from January 2014 through February 2016...
January 3, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28059841/insights-into-cardiorenal-interactions-in-acute-decompensated-heart-failure
#3
Feras M Bader, Nizar Attallah
PURPOSE OF REVIEW: Acute decompensated heart failure (ADHF) is one of the biggest challenges in the management of chronic heart failure. Despite the advances in medical and device therapy, high readmission and mortality rates continue to be a burden on healthcare systems worldwide. One of the strongest predictors of adverse outcomes in ADHF is renal dysfunction, referred to as cardiorenal syndrome (CRS) type 1. This review discusses some of the recently introduced findings related to the pathophysiology, diagnosis, and management of this disorder...
January 3, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28057363/association-of-new-york-heart-association-functional-class-iv-symptoms-at-admission-and-clinical-features-with-outcomes-in-patients-hospitalized-for-acute-heart-failure-syndromes
#4
Ryotaro Asano, Katsuya Kajimoto, Toshiaki Oka, Ryo Sugiura, Hisayuki Okada, Kazuho Kamishima, Tetsuo Hirata, Naoki Sato
BACKGROUND: It remains unclear whether there are subgroups of acute heart failure syndromes (AHFS) patients in whom New York Heart Association (NYHA) class IV symptoms at admission is related to a higher risk of mortality because of the heterogeneity of this patient population. The aim of this study was to evaluate the association of NYHA class IV symptoms at baseline with in-hospital mortality in subgroups of patients with AHFS. METHODS AND RESULTS: Of the 4842 patients enrolled in the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, 4786 patients were included in this analysis...
December 26, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28050472/use-of-lung-ultrasound-for-diagnosing-acute-heart-failure-in-emergency-department-of-southern-india
#5
Manav Aggarwal, Mrigakshi Gupta, Vikrant Vijan, Anjith Vupputuri, Sanjeev Chintamani, Bishnukiran Rajendran, Rajesh Thachathodiyal, Rajiv Chandrasekaran
INTRODUCTION: Diagnosing heart failure is often a challenge for the healthcare providers due to it's non-specific and usually subtle physical presentations. The outcomes for treatment are strongly related to the stage of the disease. Considering the importance of early and accurate diagnosis, it is important to have an easy, inexpensive, non-invasive, reliable and reproducible method for diagnosis of heart failure. Recent advancement in radiology and cardiology are supporting the emerging technique of lung ultrasound through B-line evaluation for identifying extravascular lung water...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28045409/turkish-registry-for-diagnosis-and-treatment-of-acute-heart-failure-taktik-study
#6
Mehmet Eren, Mehdi Zoghi, Mustafa Tuncer, Yüksel Çavuşoğlu, Recep Demirbağ, Mahmut Şahin, Osman Akın Serdar, Ersel Onrat, Haşim Mutlu, Dursun Dursunoğlu, Mehmet Birhan Yılmaz, Ahmet Temizhan
OBJECTIVE: The goal of this study was to develop a national database of patients hospitalized in Turkey with acute heart failure (AHF) using evaluations of diagnostic and therapeutic approaches. METHODS: Patient data were collected using an Internet-based survey. A total of 588 patients were enrolled from 36 participating medical centers across the country. RESULTS: Mean age was 62±13 years and 38% of the patients were female. Ratio of de novo AHF to study cohort was 24%...
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28040759/novel-application-of-a-percutaneous-left-ventricular-assist-device-as-a-bridge-to-transplant-in-a-paediatric-patient-with-severe-heart-failure-due-to-viral-myocarditis
#7
Paul Perry, Elizabeth David, Broadus Atkins, Gary Raff
A 13-year obese female with suspected viral myocarditis presented with acute decompensated heart failure. Due to her body habitus, she was a poor candidate for immediate heart transplantation. A peripherally inserted left ventricular assist device (LVAD) was implanted via the right axillary artery. Following device insertion the patient experienced rapid improvement in symptoms. The LVAD provided effective left ventricular unloading for 50 days, promoting myocardial recovery and maintaining excellent patient performance status...
December 31, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28040396/the-prognostic-impact-of-gender-in-patients-with-acute-heart-failure-an-evaluation-of-the-age-of-female-patients-with-severely-decompensated-acute-heart-failure
#8
Ayaka Nozaki, Akihiro Shirakabe, Noritake Hata, Nobuaki Kobayashi, Hirotake Okazaki, Masato Matsushita, Yusaku Shibata, Suguru Nishigoori, Saori Uchiyama, Yoshiki Kusama, Kuniya Asai, Wataru Shimizu
BACKGROUND: The gender differences in the prognosis of Asian patients with acute heart failure (AHF) remain to be elucidated. METHODS AND RESULTS: One thousand fifty AHF patients were enrolled. The patients were assigned to a female group (n=354) and a male group (n=696). A Kaplan-Meier curve showed that the cardiovascular survival rate of the female group was significantly lower than that of the male group (p=0.005). A multivariate Cox regression model identified female gender [hazard ratio (HR): 1...
December 28, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/28034373/body-weight-change-during-and-after%C3%A2-hospitalization-for-acute-heart%C3%A2-failure-%C3%A2-patient-characteristics-markers-of-congestion-and-outcomes-findings-from-the-ascend-hf-trial
#9
Andrew P Ambrosy, Lukasz P Cerbin, Paul W Armstrong, Javed Butler, Adrian Coles, Adam D DeVore, Mark E Dunlap, Justin A Ezekowitz, G Michael Felker, Marat Fudim, Stephen J Greene, Adrian F Hernandez, Christopher M O'Connor, Philip Schulte, Randall C Starling, John R Teerlink, Adriaan A Voors, Robert J Mentz
OBJECTIVES: This study sought to examine the relationships between in-hospital and post-discharge body weight changes and outcomes among patients hospitalized for acute heart failure (AHF). BACKGROUND: Body weight changes during and after hospitalization for AHF and the relationships with outcomes have not been well characterized. METHODS: A post hoc analysis was performed of the ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure) trial, which enrolled patients admitted for AHF regardless of ejection fraction...
January 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28030747/factors-associated-with-and-prognostic-implications-of-cardiac-troponin-elevation-in-decompensated-heart-failure-with-preserved-ejection-fraction-findings-from-the-american-heart-association-get-with-the-guidelines-heart-failure-program
#10
Ambarish Pandey, Harsh Golwala, Shubin Sheng, Adam D DeVore, Adrian F Hernandez, Deepak L Bhatt, Paul A Heidenreich, Clyde W Yancy, James A de Lemos, Gregg C Fonarow
Importance: Elevated levels of cardiac troponins are associated with adverse clinical outcomes among patients with heart failure (HF) and reduced ejection fraction. However, the clinical significance of troponin elevation in the setting of decompensated HF with preserved ejection fraction (HFpEF) is not well established. Objective: To determine the clinical predictors of troponin elevation and its association with in-hospital and long-term outcomes among patients with decompensated HFpEF...
December 28, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/28028584/the-prognostic-significance-of-atrial-fibrillation-in-heart-failure-with-preserved-ejection-function-insights-from-karen-a-prospective-and-multicenter-study
#11
Christian Bosseau, Erwan Donal, Lars H Lund, Emmanuel Oger, Camilla Hage, Geneviève Mulak, Jean-Claude Daubert, Cecilia Linde
The prognostic value of atrial fibrillation (AF) in heart failure with preserved ejection fraction (HFPEF) remains controversial. We sought to study the prognostic value of AF in a prospective cohort and to characterize the HFPEF patients with AF. KaRen was a prospective, multicenter, international, observational study intended to characterize HFPEF; 538 patients presenting with an acute decompensated cardiac failure and a left ventricular EF > 45% were included. EKG and echocardiogram performed 4-8 week following the index hospitalization were analyzed in core centers...
December 27, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/28017346/body-weight-change-during-and-after%C3%A2-hospitalization-for-acute-heart%C3%A2-failure-%C3%A2-patient-characteristics-markers-of-congestion-and-outcomes-findings-from-ascend-hf
#12
Andrew P Ambrosy, Lukasz P Cerbin, Paul W Armstrong, Javed Butler, Adrian Coles, Adam D DeVore, Mark E Dunlap, Justin A Ezekowitz, G Michael Felker, Marat Fudim, Stephen J Greene, Adrian F Hernandez, Christopher M O'Connor, Philip Schulte, Randall C Starling, John R Teerlink, Adriaan A Voors, Robert J Mentz
OBJECTIVES: This study sought to examine the relationships between in-hospital and post-discharge body weight changes and outcomes among patients hospitalized for acute heart failure (AHF). BACKGROUND: Body weight changes during and after hospitalization for AHF and the relationships with outcomes have not been well characterized. METHODS: A post hoc analysis was performed of the ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure) trial, which enrolled patients admitted for AHF regardless of ejection fraction...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017276/patient-journey-in-decompensated-heart-failure-an-analysis-in-departments-of-cardiology-and-geriatrics-in-the-greater-paris-university-hospitals
#13
Florent Laveau, Nadjib Hammoudi, Emmanuelle Berthelot, Joël Belmin, Patrick Assayag, Ariel Cohen, Thibaud Damy, Denis Duboc, Olivier Dubourg, Albert Hagege, Olivier Hanon, Richard Isnard, Guillaume Jondeau, Florian Labouree, Damien Logeart, Nicolas Mansencal, Christophe Meune, Eric Pautas, Yves Wolmark, Michel Komajda
BACKGROUND: Hospitalization for worsening/acute heart failure is increasing in France, and limited data are available on referral/discharge modalities. AIM: To evaluate patients' journeys before and after hospitalization for this condition. METHODS: On 1 day per week, between October 2014 and February 2015, this observational study enrolled 260 consecutive patients with acute/worsening heart failure in all 10 departments of cardiology and four of the departments of geriatrics in the Greater Paris University Hospitals...
December 21, 2016: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28011313/prognostic-value-of-high-sensitivity-cardiac-troponin-t-compared-to-riskscores-in-stable-cardiovascular-disease
#14
Moritz Biener, Evangelos Giannitsis, Manuel Kuhner, Thomas Zelniker, Matthias Mueller-Hennessen, Mehrshad Vafaie, Dietmar Trenk, Franz-Josef Neumann, Willibald Hochholzer, Hugo A Katus
BACKGROUND: Risk stratification of patients with cardiovascular disease remains challenging despite consideration of risk scores. METHODS: We aimed to evaluate the prognostic performance of high-sensitivity cardiac troponin T (hs-cTnT) in a low-risk outpatient population presenting for non-secondary and secondary prevention. All-cause mortality, a composite of all-cause mortality, acute myocardial infarction and stroke (endpoint 2) and a composite of all-cause mortality, acute myocardial infarction, stroke and re-hospitalization for acute coronary syndrome and decompensated heart failure (endpoint 3) were defined...
December 20, 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/28008296/point-of-care-ultraportable-echocardiography-predicts-diuretic-response-in-patients-admitted-with-acute-decompensated-heart-failure
#15
Dena K Krishnan, Barbara Pawlaczyk, Peter A McCullough, Susan Enright, Arvind Kunadi, Thomas E Vanhecke
BACKGROUND: Routine management of patients with acute decompensated heart failure (ADHF) requires careful attentiveness to fluid status and diuretic treatment efficacy. New advances in ultrasound have made ultraportable echocardiography (UE) available to physicians for point-of-care use. The purpose of this study is to explore physiologic measures of intravascular fluid volume derived from UE and explore predictors of diuretic response in ADHF. METHODS: Various echocardiography imaging measurements, particularly diameter and collapse of inferior vena cava (IVC), were collected from 77 patients admitted with a primary diagnosis of ADHF...
2016: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/28005170/improv-ed-study-outcomes-after-discharge-for-an-episode-of-acute-decompensated-heart-failure-and-comparison-between-patients-discharged-from-the-emergency-department-and-hospital-wards
#16
Òscar Miró, Víctor Gil, Carolina Xipell, Carolina Sánchez, Sira Aguiló, Francisco J Martín-Sánchez, Pablo Herrero, Javier Jacob, Alexandre Mebazaa, Veli-Pekka Harjola, Pere Llorens
OBJECTIVE: To define the short- and mid-term outcomes of patients discharged after an episode of acute-decompensated heart failure (ADHF) and evaluate the differences between patients discharged directly from the emergency department (ED) and those discharged after hospitalization. METHODS: We performed a prospective, multicenter, cohort-designed study, including consecutive patients diagnosed with ADHF in 27 Spanish EDs. Thirty-four variables on epidemiology, comorbidity, baseline status, vital signs, signs of congestion, laboratory tests, and treatment were collected in every patient...
December 22, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27990720/a-functional-variant-of-the-neuropeptide-s-receptor-1-gene-modulates-clinical-outcomes-and-healthcare-utilization-in-patients-with-systolic-heart-failure-results-from-the-interdisciplinary-network-heart-failure-inh-study
#17
Christiane E Angermann, Mathias Kaspar, Almuth Marx, Sarah Kittel-Schneider, Dominik Menhofer, Stefan Störk, Georg Ertl, Katharina Domschke, Jürgen Deckert, Andreas Reif
AIMS: Psychopathologies may occur in heart failure (HF) and can be associated with adverse outcomes. Amongst neuropeptide S receptor gene functional sequence variants, the T-allele [asparagine(107)isoleucine, NPSR1 rs324981] has been identified as a risk factor for increased anxiety/overinterpretation of bodily symptoms. We investigated all-cause death and re-hospitalization (composite primary endpoint, CPEP) and healthcare utilization in patients hospitalized for decompensated systolic HF with the TT vs...
December 18, 2016: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27972086/budget-impact-analysis-of-standard-care-with-serelaxin-in-treatment-of-patients-with-acute-decompensated-heart-failure
#18
G Tolordava, E Arinina, R Yagudina, A Kulikov
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27972082/cost-effectiveness-analysis-of-serelaxin-in-treatment-of-patients-with-acute-decompensated-heart-failure
#19
G Tolordava, E Arinina, R Yagudina, A Kulikov
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27970284/tct-122-use-of-the-impella-5-0-circulatory-support-device-for-bridge-to-decision-during-acute-decompensation-of-advanced-heart-failure
#20
Shelley Hall, Nir Uriel, Sandra Carey, Michelle Edens, Michele Esposito, Ryan O'Kelly, Shiva Annamalai, Nima Aghili, Sirtaz Adatya, Navin Kapur
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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