keyword
MENU ▼
Read by QxMD icon Read
search

Rheumatic heart disease

keyword
https://www.readbyqxmd.com/read/27924645/cardiovascular-outcomes-and-tumour-necrosis-factor-antagonists-in-chronic-inflammatory-rheumatic-disease-a-focus-on-rheumatoid-arthritis
#1
Giuliano Tocci, Delia Goletti, Valentina Marino, Andrea Matucci, Giuseppe Maria Milano, Fabrizio Cantini, Raffaele Scarpa
Many chronic rheumatic diseases have an inflammatory etiology, leading to accelerated atherosclerosis and increased occurrence of vascular diseases. In rheumatoid arthritis (RA), a reduction in cardiovascular (CV) events has been reported under treatments reducing systemic inflammation. Areas covered: Given the central role of tumour necrosis factor alpha (TNFα) in chronic inflammatory conditions and in atherosclerosis, it has been suggested that TNFα-antagonists may reduce CV risk and mortality. Although there are no randomized controlled or head-to-head trials investigating the effect of specific anti-TNF-agents on CV outcomes, observational cohort studies, national registry data, and meta-analyses in RA have reported improved CV outcomes with anti-TNF therapy...
December 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/27920275/hypermethylation-of-brain-natriuretic-peptide-bnp-gene-is-associated-with-the-risk-of-rheumatic-heart-disease
#2
Ni Li, Dawei Zheng, Lebo Sun, Huoshun Shi, Xiuying Zhu, Guodong Xu, Qinning Wang, Caimin Zhu, Guofeng Shao
To investigate the contribution of BNP promoter DNA methylation to the risk of rheumatic heart disease (RHD) and the influence of warfarin anticoagulant therapy on BNP methylation levels for RHD patients after surgery.BNP methylation levels were determined by bisulfite pyrosequencing from plasma samples of RHD patients compared with healthy controls. Several factors influencing the RHD patients were included age, smoking, and cholesterol levels. A fragment of 5 CG sites (CpG1-5) in the promoter region of BNP gene was measured...
December 5, 2016: Bioscience Reports
https://www.readbyqxmd.com/read/27918954/interleukin-10-role-in-increasing-susceptibility-and-pathogenesis-of-rheumatic-fever-rheumatic-heart-disease
#3
REVIEW
Neha Sharma, Devinder Toor
Streptococcus pyogenes (group A streptococcus) causes rheumatic fever (RF) which later progresses towards rheumatic heart disease (RHD) in the susceptible individuals. RF and RHD both contribute towards increasing global burden of disease, especially in developing countries. RHD is one of the most common acquired heart diseases causing permanent damage to heart valves which ultimately leads to heart failure. In RHD, heart valve lesions are formed which are mediated by autoimmune reaction between streptococcal antigens (M protein and group A carbohydrate epitope GlcNAc) and heart tissues...
December 2, 2016: Cytokine
https://www.readbyqxmd.com/read/27910004/dabigatran-overdose-a-case-report-of-acute-hepatitis-extracorporeal-treatment
#4
Mariagrazia Porru, Antonella Mameli, Maria E Cianchetti, Mario Musu, Paola Schirru, Maria F Ruberto, Doris Barcellona, Francesco Marongiu
Dabigatran is an oral, direct thrombin inhibitor approved by international regulatory agencies for stroke prevention in patients with paroxysmal or persistent non-rheumatic atrial fibrillation (AF). The benefits of dabigatran are widely described, but its use in the geriatric population is not without risk. Chronic kidney disease is a common comorbidity with AF, and thus frequent checks of renal function in elderly patients are recommended. We report a case of dabigatran intoxication in an elderly man affected by heart failure and worsening renal function, who developed acute hepatitis and coma, which was successfully treated with continuous veno-venous hemodiafiltration...
December 1, 2016: International Journal of Hematology
https://www.readbyqxmd.com/read/27908608/a-hospital-based-survey-of-patients-with-severe-valvular-heart-disease-in-china
#5
Po Hu, Xian-Bao Liu, Jie Liang, Qi-Feng Zhu, Chao-Xia Pu, Meng-Yao Tang, Jian-An Wang
OBJECTIVES: Due to increasing aging, the epidemiology of VHD may have changed in China. This study aimed to provide contemporary information on the prevalence, distribution patterns, and etiology of severe VHD in China. METHODS: This was a retrospective survey at Second Affiliated Hospital of Zhejiang University, which included all consecutive patients between 2010 and 2015. RESULTS: In all, 139,496 patients were enrolled. Among severe valve diseases, MR was the most frequent (n=946, 0...
November 25, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27906042/what-is-the-impact-of-biologic-therapies-on-common-co-morbidities-in-patients-with-rheumatoid-arthritis
#6
REVIEW
Jenny Humphreys, Kimme Hyrich, Deborah Symmons
Biologic therapies have revolutionised disease control in patients with rheumatoid arthritis (RA). Theoretically, they have the potential to influence co-morbid disease associated with RA through better control of systemic inflammation. Conversely, co-morbidity may occur as an adverse effect of the drugs. The latest evidence from observational data shows an increased risk of infection in the first 6 months of treatment with tumour necrosis factor inhibitor (TNFi) therapies and potentially other biologic therapies...
December 1, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27904843/cardiac-surgery-in-africa-a-thirty-five-year-experience-on-open-heart-surgery-in-cote-d-ivoire
#7
Koffi Herve Yangni-Angate, Christophe Meneas, Florent Diby, Manga Diomande, Anicet Adoubi, Yves Tanauh
BACKGROUND: Few centers for open heart surgery (OHS) are in Sub-Saharan Africa. Lack of OHS results is also noted. By reporting our African experience on OHS, the aim of this study was to fill the gap. METHODS: It is a retrospective study on 2,612 patients who were subject to an OHS between 1978 and 2013. Data were collected from demographical, clinical, investigative studies, surgical and outcomes parameters. RESULTS: There were 1,475 cases of rheumatic heart diseases (RHD), 126 endomyocardial fibrosis (EMF), 741 congenital heart diseases (CHDs) and 270 various affections...
October 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/27904841/the-rebirth-of-cardiac-surgery-in-sudan
#8
Ahmed ElSayed, Elamin Elawad Elnur
BACKGROUND: Cardiac surgery is nowadays an integral part of a complete national health service. METHODS: In this paper the rebirth of cardiac surgery in Sudan from 1998 till 2007 is given by means of a literature search, personal interviews and searching hospital records. RESULTS: A summary of the initial birth of these services in 1959 till its demise in 1993 is first mentioned to set the stage for the subsequent period of sustainable growth...
October 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/27892897/the-importance-of-selected-spices-in-cardiovascular-diseases
#9
Bartosz Kulczyński, Anna Gramza-Michałowska
Cardiovascular diseases are the leading cause of death worldwide. Literature data indicate that, due to these diseases, approximately 17.5 million people died in 2012. Types of cardiovascular disease include ischemic heart disease, cerebrovascular disease, peripheral vascular disease, congenital heart disease, rheumatic heart disease, cardiomyopathy and arrhythmia. Proper nutrition is an important factor in reducing the risk of cardiovascular events. An interesting element of our diets is spices. For thousands of years, they have been used in the treatment of many diseases: bacterial infections, coughs, colds, and liver diseases...
November 14, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/27886787/rheumatic-heart-disease-the-unfinished-global-agenda
#10
REVIEW
Shanti Nulu, Gene Bukhman, Gene F Kwan
Primarily affecting the young, rheumatic heart disease (RHD) is a neglected chronic disease commonly causing premature morbidity and mortality among the global poor. Standard clinical prevention and treatment is based on studies from the early antimicrobial era, as research investment halted soon after the virtual eradication of the disease from developed countries. The emergence of new global data on disease burden, new technologies, and a global health equity platform have revitalized interest and investment in RHD...
February 2017: Cardiology Clinics
https://www.readbyqxmd.com/read/27886692/cardiovascular-disease-risk-in-patients-with-rheumatic-diseases
#11
REVIEW
Rachel H Mackey, Lewis H Kuller, Larry W Moreland
Evidence suggests the greater than 1.5 increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) is related to an accelerated burden of subclinical atherosclerosis that develops before the diagnosis of RA. Dyslipidemia in RA is better quantified by lipoproteins and apolipoproteins than cholesterol levels. Current risk factors likely underestimate CVD risk partly by underestimating prior risk factor levels. To reduce CVD risk in RA, control disease activity and aggressively treat CVD risk factors...
February 2017: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/27883978/outcomes-of-borderline-rheumatic-heart-disease-a-prospective-cohort-study
#12
Geneviève Bertaina, Bernard Rouchon, Bertrand Huon, Nina Guillot, Corinne Robillard, Baptiste Noël, Marie Nadra, Christophe Tribouilloy, Eloi Marijon, Xavier Jouven, Mariana Mirabel
CONTEXT AND AIMS: The advent of systematic screening for rheumatic heart disease (RHD) by echocardiography in endemic regions has led to a new entity: borderline RHD. The pathogenicity and natural history of borderline RHD needs to be addressed. The aim of this study was to assess the outcomes of children detected by echocardiography as having borderline RHD. METHODS: Schoolchildren in 4th grade (i.e., aged 9-10years) who were prospectively echo-screened for RHD (2012-2014) in Nouméa, New Caledonia, were asked to participate...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27883972/rheumatic-heart-disease-in-a-developing-country-incidence-and-trend-monastir-tunisia-2000-2013
#13
Asma Sriha Belguith, Afifa Koubaa Abdelkafi, Sana El Mhamdi, Manel Ben Fredj, Hela Abroug, Arwa Ben Salah, Inès Bouanene, Fahima Hassine, Amal Amara, Sana Bhiri, Abdelkarim Derbel, Habib Gamra, Faouzi Maatouk, Mohamed Soussi Soltani
BACKGROUND: The penicillin therapy of β hemolytic streptococcal pharyngitis has aided in the decrease of rheumatic heart disease (RHD) in developing countries. Tunisia is an endemic area, however, and incidence of RHD is weakly documented. We aimed at establishing the standardized incidence rate (SIR) of RHD in Monastir governorate and at determining RHD prevalence among hospitalized patients in two cardiology departments. METHODS: From the regional register of Monastir Hospital morbidity, we have selected newly diagnosed patients with RHD, residents of Monastir, and hospitalized to the 2 cardiology departments between 2000 and 2013 (2001 not included)...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27876696/stroke-prevention-strategies-in-patients-with-atrial-fibrillation-and-heart-valve-abnormalities-perceptions-of-valvular-atrial-fibrillation-results-of-the-european-heart-rhythm-association-survey
#14
Tatjana S Potpara, Gregory Y H Lip, Torben B Larsen, Antonio Madrid, Dan Dobreanu, Ewa Jędrzejczyk-Patej, Nikolaos Dagres
The purpose of this European Heart Rhythm Association (EHRA) Survey was to assess the perceptions of 'valvular' atrial fibrillation (AF) and management of AF patients with various heart valve abnormalities in daily clinical practice in European electrophysiology (EP) centres. Questionnaire survey was sent via the Internet to the EHRA-EP Research Network Centres. Of the 52 responding centres, 42 (80.8%) were university hospitals. Choosing the most comprehensive definition of valvular AF, a total of 49 centres (94...
October 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27876001/severe-mitral-regurgitation-due-to-mitral-leaflet-aneurysm-diagnosed-by-three-dimensional-transesophageal-echocardiography-a-case-report
#15
Takao Konishi, Naohiro Funayama, Tadashi Yamamoto, Daisuke Hotta, Kenjiro Kikuchi, Katsumi Ohori, Hiroshi Nishihara, Shinya Tanaka
BACKGROUND: A small mitral valve aneurysm (MVA) presenting as severe mitral regurgitation (MR) is uncommon. CASE PRESENTATION: A 47-year-old man with a history of hypertension complained of exertional chest discomfort. A transthoracic echocardiogram (TTE) revealed the presence of MR and prolapse of the posterior leaflet. A 6-mm in diameter MVA, not clearly visualized by TTE, was detected on the posterior leaflet on a three-dimensional (3D) transesophageal echocardiography (TEE)...
November 22, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27868419/-research-progress-on-pharmacotherapy-of-calcific-aortic-valve-disease
#16
Miaomiao DU, Gaigai Ma, Yuping Shi
With the population aging and declining incidence of rheumatic heart disease, calcific aortic valve disease (CAVD) has become the most frequent valve disease and the common cause of aortic valve replacement. Patients with CAVD need to cope with a deteriorating quality of life and valve replacement is the only effective clinical option for the patients. Therefore, early pharmacotherapy is of great significance in prevention or slow-down of the progression of CAVD. For years CAVD was considered to be a passive wear and tear process of valves, but now it is recognized as an active and multi-factorial process...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/27867464/rheumatic-fever-and-rheumatic-heart-disease-a-historical-perspective
#17
Rachel Hajar
No abstract text is available yet for this article.
July 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27861628/characteristics-of-infective-endocarditis-in-a-tertiary-hospital-in-east-china
#18
Huimin Xu, Siyu Cai, Haibin Dai
The epidemiology, clinical presentation, and treatment of infective endocarditis (IE) has significantly changed over the past few years in developed countries. However, relevant data from developing countries are different and remain scarce. The objective of this study was to evaluate the clinical presentations, treatment and outcomes of IE patients in a tertiary hospital in East China over an 8-year period. This was a retrospective observational study of consecutive cases of definite or possible IE as per the modified Duke criteria between January 2008 and December 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27861189/oral-anticoagulation-for-stroke-prevention-amongst-atrial-fibrillation-patients-with-valvular-heart-disease-an-update
#19
Andrew C T Ha, Atul Verma, Subodh Verma
PURPOSE OF REVIEW: The majority of evidence on the safety and efficacy of oral anticoagulation for stroke prevention amongst patients with atrial fibrillation is derived from those without significant valvular heart disease. This article will review current knowledge, areas of uncertainty and controversy, and ongoing research on oral anticoagulation for stroke prevention amongst patients with valvular heart disease. RECENT FINDINGS: The rates of stroke, systemic embolism, and major bleeding were similar for patients with and without significant native valvular disease when treated with direct oral anticoagulants (DOACs) or vitamin K antagonists...
November 18, 2016: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/27855287/the-burden-and-implications-of-preoperative-atrial-fibrillation-in-australian-heart-valve-surgery-patients
#20
E Anne Russell, Warren F Walsh, Lavinia Tran, Robert Tam, Christopher M Reid, Alex Brown, Jayme S Bennetts, Robert A Baker, Graeme P Maguire
BACKGROUND: Atrial fibrillation (AF) is the most common preoperative arrhythmia in heart valve surgery patients and its prevalence is rising. This study aims to investigate the impact of AF on valve surgery early complications and survival and on valve disease of different aetiologies and populations with particular reference to Indigenous Australians with rheumatic heart disease (RHD). METHODS: The Australian and New Zealand Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database was analysed to determine the association between preoperative AF and valve surgery outcome...
November 9, 2016: International Journal of Cardiology
keyword
keyword
23656
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"