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https://www.readbyqxmd.com/read/28721865/eliminating-acute-rheumatic-fever-and-rheumatic-heart-disease
#1
Magdi Yacoub, Bongani Mayosi, Ahmed ElGuindy, Alain Carpentier, Salim Yusuf
No abstract text is available yet for this article.
July 15, 2017: Lancet
https://www.readbyqxmd.com/read/28718586/-adverse-events-of-biologic-therapies
#2
Gregory Fleury, Cem Gabay
Biological therapies have revolutionized the management and the outcome of patients with inflammatory rheumatic diseases. The prescription and the number of patients under biotherapies have greatly increased. Unfortunately, these treatments are occasionally accompanied by side effects usually reversible upon treatment discontinuation. Some are preventable or can be reduced, including through the screening and prevention (tuberculosis screening, vaccination…). It is important to be aware of these different side effects to adapt the prescription of biologics according to the patient's profile (history of infection, malignancy, heart failure…)...
March 8, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28716486/the-impact-of-a-peer-support-group-for-children-with-rheumatic-heart-disease-in-uganda
#3
Amy Scheel, Andrea Beaton, Emmy Okello, Chris T Longenecker, Isaac Omara Otim, Peter Lwabi, Craig Sable, Allison R Webel, Twalib Aliku
OBJECTIVE: To assess the impact of a peer-support group on knowledge, quality of life, and social support for children with rheumatic heart disease (RHD). METHODS: Children diagnosed with RHD and receiving 4-weekly injectable penicillin were invited to participate in a monthly support group for 6 months. Pre- and post-intervention assessments included a baseline RHD knowledge assessment, a measure of health related quality of life (HRQOL) (PedsQLTM4.0), and a measure of social support (Hawthorne Friendship Scale)...
July 11, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28702827/a-case-of-atrial-cardiomyopathy-in-a-patient-with-rheumatic-heart-disease-with-massive-left-atrial-calcification
#4
Megumi Shimada, Makoto Akaishi, Atsuko Hara
No abstract text is available yet for this article.
July 12, 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/28700476/peripheral-monocytosis-as-a-predictive-factor-for-adverse-outcome-in-the-emergency-department-survey-based-on-a-register-study
#5
Mathias Hensel, Lena Grädel, Alexander Kutz, Sebastian Haubitz, Andreas Huber, Beat Mueller, Philipp Schuetz, Thomas Hügle
Monocytosis is associated with chronic infections such as tuberculosis or endocarditis as well as rheumatic and myeloproliferative disorders. Monocytes are also involved in the pathogenesis of atherosclerosis, coronary artery disease, and stroke. The value of monocytosis as a prognostic marker in different diagnostic groups in the emergency setting, however, has not been investigated so far.The aim of the article is to study monocytosis as an outcome factor in the emergency setting.In a Swiss register study, we analyzed monocyte counts in 4238 patients aged >18 years who were admitted to the emergency department of a regional tertiary care hospital...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28690220/-investigation-and-analysis-for-current-situation-and-pathogenesis-relevant-to-pulmonary-hypertension
#6
Si Lei, Doudou Tang, Nianru Xu, Shangjie Wu
To investigate the demographic characteristics and the causes for pulmonary hypertension (PH) in adult patients.
 Methods: A total of 2 508 adult patients diagnosed as PH, who came from the Second Xiangya Hospital of Central South University from January 2010 to December 2014, were retrospectively investigated. All subjects underwent the clinical diagnosis, or the echocardiographic diagnosis, or thetraditional hemodynamic criteria by right heart catheterization (RHC). The patient's data including hospital numbers, gender, ages, primary diseases, etc, are collected and analyzed...
June 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28683722/epidemiology-of-pharyngitis-as-reported-by-zambian-school-children-and-their-families-implications-for-demand-side-interventions-to-prevent-rheumatic-heart-disease
#7
John Musuku, Joyce C Lungu, Elizabeth Machila, Catherine Jones, Laurence Colin, Sherri Schwaninger, Patrick Musonda, Brigitta Tadmor, Jonathan M Spector, Mark E Engel, Liesl J Zühlke
BACKGROUND: Prompt and appropriate treatment of streptococcal pharyngitis decreases the risk of acute rheumatic fever and rheumatic heart disease (RHD). Understanding public perceptions and behaviors related to sore throat is fundamental to inform health programs aimed at eliminating new cases of RHD in endemic regions. We sought to describe the epidemiology of pediatric pharyngitis and its treatment, as reported by children and their parents or guardians in Lusaka, Zambia. METHODS: This was a cross-sectional investigation using interviews and written surveys, nested in a school-based RHD prevalence study...
July 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28681803/molecular-biology-of-group-a-streptococcus-and-its-implications-in-vaccine-strategies
#8
REVIEW
N K Brahmadathan
Infections due to Streptococcus pyogenes and their complications are a problem of major concern in many countries, including India. Primary prophylaxis with benzathine penicillin is the key to control and prevent sequelae such as acute rheumatic fever and rheumatic heart disease (RF/RHD) or post-streptococcal glomerulonephritis (PSGN). Non-compliance to prophylaxis due to fear of injection and anaphylaxis is major issues in RF/RHD control in India and leads to continued high prevalence of infection and post-streptococcal sequelae...
April 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28678926/late-results-of-cox-maze-iii-procedure-in-patients-with-atrial-fibrillation-associated-with-structural-heart-disease
#9
Gustavo Gir Gomes, Wagner Luis Gali, Alvaro Valentim Lima Sarabanda, Claudio Ribeiro da Cunha, Iruena Moraes Kessler, Fernando Antibas Atik
Background: Cox-Maze III procedure is one of the surgical techniques used in the surgical treatment of atrial fibrillation (AF). Objectives: To determine late results of Cox-Maze III in terms of maintenance of sinus rhythm, and mortality and stroke rates. Methods: Between January 2006 and January 2013, 93 patients were submitted to the cut-and-sew Cox-Maze III procedure in combination with structural heart disease repair. Heart rhythm was determined by 24-hour Holter monitoring...
June 29, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28678069/echocardiographic-assessment-of-mitral-stenosis-orifice-area-a-comparison-of-a-novel-three-dimensional-method-versus-conventional-techniques
#10
Sergey Karamnov, Nelson Burbano-Vera, Chuan-Chin Huang, John A Fox, Stanton K Shernan
BACKGROUND: A comprehensive evaluation of mitral stenosis (MS) severity commonly utilizes two-dimensional (2D) echocardiography techniques. However, the complex three-dimensional (3D) structure of the mitral valve (MV) poses challenges to accurate measurements of its orifice area by 2D imaging modalities. We aimed to assess MS severity by comparing measurements of the MV orifice area using conventional echocardiography methods to 3D orifice area (3DOA), a novel echocardiographic technique which minimizes geometric assumptions...
July 1, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28673022/secondary-prevention-for-screening-detected-rheumatic-heart-disease-opportunities-to-improve-adherence
#11
Daniel Engelman, Maureen Ah Kee, Reapi L Mataika, Joseph H Kado, Samantha M Colquhoun, Jim Tulloch, Andrew C Steer
Background: Secondary prevention is an effective treatment for rheumatic heart disease (RHD), but ensuring high adherence to prophylaxis over many years is challenging and requires understanding of local factors. Methods: Participants were young people diagnosed with RHD through echocardiographic screening in Fiji. We used a structured interview to evaluate the following: health seeking behaviours; attitudes, practice, barriers and potential improvement strategies for adherence to antibiotic prophylaxis; and adolescent-friendly qualities of the health service...
April 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28671804/valvular-heart-disease-in-adults-etiologies-classification-and-diagnosis
#12
Steven M Hollenberg
The prevalence of valvular heart disease (VHD) in the United States was estimated to be approximately 2.5% in the 1990s. The prevalence currently is thought to be increasing because of more accurate diagnostic methods and aging of the population. Mitral regurgitation (MR) is the most common valve defect, followed by aortic stenosis (AS) and aortic regurgitation (AR). Degenerative disease is the most common etiology of MR, AS, and AR, though these forms of VHD also can be caused by congenital valve defects, systemic inflammatory diseases, endocarditis, and many other conditions...
June 2017: FP Essentials
https://www.readbyqxmd.com/read/28662157/sex-dependent-aortic-valve-pathology-in-patients-with-rheumatic-heart-disease
#13
Feng Xiao, Rui Zheng, Di Yang, Kejiang Cao, Shijiang Zhang, Bingruo Wu, Yongfeng Shao, Bin Zhou
BACKGROUND: Rheumatic heart disease is an autoimmune disease caused by group A streptococci infection and frequently affects the aortic valve. Sex differences are common in the disease progression, treatment, and outcome. However, little is known about the sex differences in the pathology of aortic valves in rheumatic heart disease. DESIGN: We studied the end-stage calcific aortic valves from male versus female patients to reveal the sex-dependent pathology differences and molecular changes associated with requiring valve replacement...
2017: PloS One
https://www.readbyqxmd.com/read/28659116/cardiac-care-for-indigenous-australians-practical-considerations-from-a-clinical-perspective
#14
Warren F Walsh, Nadarajah Kangaharan
Indigenous Australians have a much high burden of cardiovascular disease, which occurs at an earlier age than in the non-Indigenous population. Comorbidities such as diabetes are common. Early diagnosis of ischaemic heart disease may be difficult because of barriers such as distance to medical centres, communication problems and family and cultural responsibilities. Disparities in cardiac care between Indigenous and non-Indigenous populations are well documented, with examples including reduced angiography and revascularisation rates in Indigenous patients...
July 3, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28658377/variations-and-particularities-in-cardiovascular-disease-mortality-in-brazil-and-brazilian-states-in-1990-and-2015-estimates-from-the-global-burden-of-disease
#15
Luisa Campos Caldeira Brant, Bruno Ramos Nascimento, Valéria Maria Azeredo Passos, Bruce Bartholow Duncan, Isabela Judith Martins Bensenõr, Deborah Carvalho Malta, Maria de Fatima Marinho de Souza, Lenice Harumi Ishitani, Elizabeth França, Mateus S Oliveira, Meghan Mooney, Mohsen Naghavi, Gregory Roth, Antonio Luiz Pinho Ribeiro
Objective: To analyze variations and particularities in mortality due to cardiovascular disease (CVD) in Brazil and in Brazilian states, in 1990 and 2015. Methods: We used data compiled from the Global Burden of Disease (GBD) 2015, obtained from the database of the Mortality Information System (SIM) of the Brazilian Ministry of Health. Correction of the sub-registry of deaths and reclassification of the garbage codes were performed using specific algorithms. The cardiovascular causes were subdivided into 10 specific causes...
May 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/28652669/early-postoperative-paravalvular-leak-among-egyptian-population-an-observational-study
#16
Noha Hassanin, Yasser Sharaf, Waleed Ammar, Amr Y H Sayed
OBJECTIVES: Several reports described the incidence of postoperative paravalvular leakage (PVL) early after valve replacement surgery, however, there is a paucity of data regarding the outcomes and complications correlated to the severity of PVL. The aim of the current study was to evaluate the incidence, causes, and short term outcome of early postoperative PVL. METHODS: Data were collected from patients presenting to the cardiovascular department at Cairo University Hospital for aortic and/or mitral valve replacement surgery from May 2014 to May 2015...
July 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28623907/dna-methylation-dysregulations-in-rheumatic-heart-valve-disease
#17
Kangjun Shen, Hui Liu, Ran Jing, Jiangfeng Yi, Xinmin Zhou
BACKGROUND: The epigenetic changes underlying the development of rheumatic heart valve disease (RHVD) remain incompletely understood. Limited evidence suggests that abnormal DNA methylation might be involved in the pathogenesis of RHVD. In the present study, we evaluated the DNA methylation dysregulations from myocardial tissue in RHVD patients systematically. METHODS: Right atrial myocardial tissue obtained from rheumatic valvular patients who had undergone valve replacements surgery (n = 73) and were compared to healthy controls (n = 4)...
June 17, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28618423/long-term-clinical-outcomes-of-the-carpentier-edwards-perimount-pericardial-bioprosthesis-in-chinese-patients-with-single-or-multiple-valve-replacement-in-aortic-mitral-or-tricuspid-positions
#18
Huiming Guo, Cong Lu, Huanlei Huang, Bin Xie, Jian Liu, Shaoyi Zheng, Ruixin Fan, Jimei Chen, Jian Zhuang
OBJECTIVES: To report the safety and efficacy results of a 9- to 15-year follow-up investigation among patients who had received Carpentier-Edwards Perimount (CE-P) bovine pericardial bioprostheses (Edwards Lifesciences, Irvine, CA, USA) for valve replacement. METHODS: This retrospective study investigated freedom from structural valve deterioration (SVD) as well as survival and reoperation among different age and etiology groups in patients who were implanted with a CE-P bioprosthesis at Guangdong General Hospital between 2001 and 2007...
June 16, 2017: Cardiology
https://www.readbyqxmd.com/read/28617789/adequate-adherence-to-benzathine-penicillin-secondary-prophylaxis-following-the-diagnosis-of-rheumatic-heart-disease-by-echocardiographic-screening
#19
COMPARATIVE STUDY
Nicola Culliford-Semmens, Elizabeth Tilton, Rachel Webb, Diana Lennon, Belinda Paku, John Malcolm, Sandi French, Nikki Blair, Nigel Wilson
AIMS: The primary aim of this study was to determine adherence to benzathine penicillin (BPG) for individuals diagnosed with rheumatic heart disease (RHD) by echocardiographic screening between 2007-2012. METHODS: BPG records were obtained for 57 patients, median age 12 at time of diagnosis. A 'days at risk' analysis was undertaken. Annual adherence was calculated for each individual. A comparison with the Wellington region's Rheumatic Fever 2013 adherence data was undertaken...
June 16, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28616570/a-study-of-spectrum-of-rheumatic-heart-disease-in-a-tertiary-care-hospital-in-central-nepal
#20
S Laudari, G Subramanyam
BACKGROUND AND AIMS: Rheumatic heart disease is one of the most common cause for heart failure and associated mortalities/morbidities in the young population in developing countries like Nepal imparting huge familial, social and manpower burden. MATERIALS AND METHODS: This is a hospital based descriptive cross-sectional study during June 2014 to April 2016 over a period of 22 months at College of Medical Sciences-Bharatpur including 235 patients with clinical and/or echocardiographic evidence of definite rheumatic heart disease...
June 2017: IJC Heart & Vasculature
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