keyword
https://read.qxmd.com/read/38547461/effects-of-h-2-o-on-improving-the-performance-of-a-solid-composite-electrolyte-fabricated-via-an-air-processable-technique
#1
JOURNAL ARTICLE
Xine Fan, Yanmin Zhou, Mingda Wang, Junbao Lai, Wenzhe Shan, Zhen Xing, Hao Tang, Guiping Dai, Gaixia Zhang, Long Tan
Inert atmosphere is normally necessary for fabrication of solid composite electrolytes (SCEs) as a crucial part of solid-state Li-metal batteries in order to avoid undesirable reactions induced by ambient moisture. Herein, we developed an air-processable technique to fabricate SCEs by employing LiCF3 SO3 (LiOTf) as the Li salt, which was combined with Li6.4 La3 Zr1.4 Ta0.6 O12 (LLZTO) as the fast Li-conductor and polyvinylidene difluoroethylene/polyvinyl acetate (PVDF/PVAC) as the polymer matrix. With the assistance of trace H2 O dissolved in electrolyte solution, the room-temperature Li+ conductivity of the obtained aSCE reached as high as 5...
March 28, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38547271/a-hyperelastic-hydrogel-with-an-ultralarge-reversible-biaxial-strain
#2
JOURNAL ARTICLE
Lili Chen, Zhekai Jin, Wenwen Feng, Lin Sun, Hao Xu, Chao Wang
Hyperelastic materials exhibit a nonlinear elastic response to large strains, whereas hydrogels typically possess a low elastic range due to the nonuniform cross-linking and limited chain segments among cross-links. We developed a hyperelastic hydrogel that possesses a broader elastic range by introducing a reversible pearl-necklace structure, in which beads are connected by strings. The subnanometric beads can efficiently unfold and refold under cyclic mechanical strains; thus, the hydrogel can rapidly recover after being stretched to an areal strain of more than 10,000%...
March 29, 2024: Science
https://read.qxmd.com/read/38547216/movement-goal-relevant-object-shape-properties-act-as-poor-but-viable-cues-for-the-attribution-of-motor-errors-to-external-objects
#3
JOURNAL ARTICLE
Shanaathanan Modchalingam, Maria N Ayala, Denise Y P Henriques
When a context change is detected during motor learning, motor memories-internal models for executing movements within some context-may be created or existing motor memories may be activated and modified. Assigning credit to plausible causes of errors can allow for fast retrieval and activation of a motor memory, or a combination of motor memories, when the presence of such causes is detected. Features of the movement-context intrinsic to the movement dynamics, such as posture of the end effector, are often effective cues for detecting context change whereas features extrinsic to the movement dynamics, such as the colour of an object being moved, are often not...
2024: PloS One
https://read.qxmd.com/read/38547176/optimization-of-a-fast-and-sensitive-method-based-on-matrix-solid-phase-dispersion-lc-ms-ms-for-simultaneous-determination-of-phthalates-and-bisphenols-in-mussel-samples
#4
JOURNAL ARTICLE
Federica Castellani, Matteo Vitali, Arianna Antonucci, Giammarco Del Morrone, Luigi Cofone, Gabriele D'Ancona, Ivano Pindinello, Simonetta Mattiucci, Carmela Protano
Bisphenols and phthalates are wide classes of endocrine disrupting chemicals (EDCs) extensively used as additives in plastic products. In this study, a fast and reliable analytical method based on matrix solid-phase dispersion (MSPD) coupled with LC-MS/MS was developed and optimized for simultaneous determination of 8 bisphenols and 7 phthalates in raw mussel extract. The LC-MS/MS method was tested for linearity (R2 ), inter- and intra-day repeatability, limit of detection and quantification, both for matrix-free and matrix-matched solutions...
March 28, 2024: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://read.qxmd.com/read/38547143/quantitative-imaging-and-semiotic-phenotyping-of-mitochondrial-network-morphology-in-live-human-cells
#5
JOURNAL ARTICLE
Sophie Charrasse, Victor Racine, Charlotte Saint-Omer, Titouan Poquillon, Loïc Lionnard, Marine Ledru, Christophe Gonindard, Sandrine Delaunois, Karima Kissa, Richard E Frye, Manuela Pastore, Christelle Reynes, Mathilde Frechet, Hanane Chajra, Abdel Aouacheria
The importance of mitochondria in tissue homeostasis, stress responses and human diseases, combined to their ability to transition between various structural and functional states, makes them excellent organelles for monitoring cell health. There is therefore a need for technologies to accurately analyze and quantify changes in mitochondrial organization in a variety of cells and cellular contexts. Here we present an innovative computerized method that enables accurate, multiscale, fast and cost-effective analysis of mitochondrial shape and network architecture from confocal fluorescence images by providing more than thirty features...
2024: PloS One
https://read.qxmd.com/read/38547096/a-new-automatic-sugarcane-seed-cutting-machine-based-on-internet-of-things-technology-and-rgb-color-sensor
#6
JOURNAL ARTICLE
Liu Yang, Loai S Nasrat, Mohamed E Badawy, Daniel Eutyche Mbadjoun Wapet, Manar A Ourapi, Tamer M El-Messery, Irina Aleksandrova, Mohamed Metwally Mahmoud, Mahmoud M Hussein, Abdallah E Elwakeel
Egypt is among the world's largest producers of sugarcane. This crop is of great economic importance in the country, as it serves as a primary source of sugar, a vital strategic material. The pre-cutting planting mode is the most used technique for cultivating sugarcane in Egypt. However, this method is plagued by several issues that adversely affect the quality of the crop. A proposed solution to these problems is the implementation of a sugarcane-seed-cutting device, which incorporates automatic identification technology for optimal efficiency...
2024: PloS One
https://read.qxmd.com/read/38547056/dna-nanomachines-reveal-an-adaptive-energy-mode-in-confinement-induced-amoeboid-migration-powered-by-polarized-mitochondrial-distribution
#7
JOURNAL ARTICLE
Yixin Liu, Ya-Jun Wang, Yang Du, Wei Liu, Xuedong Huang, Zihui Fan, Jiayin Lu, Runqiu Yi, Xiao-Wei Xiang, Xinwei Xia, Hongzhou Gu, Yan-Jun Liu, Baohong Liu
Energy metabolism is highly interdependent with adaptive cell migration in vivo. Mechanical confinement is a critical physical cue that induces switchable migration modes of the mesenchymal-to-amoeboid transition (MAT). However, the energy states in distinct migration modes, especially amoeboid-like stable bleb (A2) movement, remain unclear. In this report, we developed multivalent DNA framework-based nanomachines to explore strategical mitochondrial trafficking and differential ATP levels during cell migration in mechanically heterogeneous microenvironments...
April 2, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38547054/kombucha-tea-associated-microbes-remodel-host-metabolic-pathways-to-suppress-lipid-accumulation
#8
JOURNAL ARTICLE
Rachel N DuMez-Kornegay, Lillian S Baker, Alexis J Morris, Whitney L M DeLoach, Robert H Dowen
The popularity of the ancient, probiotic-rich beverage Kombucha Tea (KT) has surged in part due to its purported health benefits, which include protection against metabolic diseases; however, these claims have not been rigorously tested and the mechanisms underlying host response to the probiotics in KT are unknown. Here, we establish a reproducible method to maintain C. elegans on a diet exclusively consisting of Kombucha Tea-associated microbes (KTM), which mirrors the microbial community found in the fermenting culture...
March 2024: PLoS Genetics
https://read.qxmd.com/read/38546986/size-tunable-manganese-doped-spheroidal-cspbcl-3-quantum-dots
#9
JOURNAL ARTICLE
Patrick von Schwerin, Markus Döblinger, Tushar Debnath, Jochen Feldmann, Quinten A Akkerman
Manganese doping has been demonstrated as a versatile tool to tune the emission of CsPbCl3 nanocrystals (NCs). Although this has been demonstrated in nanocubes and nanoplatelets, strategies for doping Mn2+ in size-tunable, excitonic CsPbCl3 quantum dots (QDs) remain absent. In this work, we demonstrate the synthesis of size-tunable spheroidal CsPbCl3 :Mn2+ QDs, which can be obtained by a water-hexane interfacial combined anion and cation exchange strategy starting from CsPbBr3 QDs. Interestingly, the QDs exhibit a fast 0...
March 28, 2024: Journal of Physical Chemistry Letters
https://read.qxmd.com/read/38546872/robust-thalamic-nuclei-segmentation-from-t1-weighted-mri-using-polynomial-intensity-transformation
#10
JOURNAL ARTICLE
Julie P Vidal, Lola Danet, Patrice Péran, Jérémie Pariente, Meritxell Bach Cuadra, Natalie M Zahr, Emmanuel J Barbeau, Manojkumar Saranathan
Accurate segmentation of thalamic nuclei, crucial for understanding their role in healthy cognition and in pathologies, is challenging to achieve on standard T1-weighted (T1w) magnetic resonance imaging (MRI) due to poor image contrast. White-matter-nulled (WMn) MRI sequences improve intrathalamic contrast but are not part of clinical protocols or extant databases. In this study, we introduce histogram-based polynomial synthesis (HIPS), a fast preprocessing transform step that synthesizes WMn-like image contrast from standard T1w MRI using a polynomial approximation for intensity transformation...
March 28, 2024: Brain Structure & Function
https://read.qxmd.com/read/38546834/integrating-recombinase-polymerase-amplification-and-photosensitization-colorimetric-detection-in-one-tube-for-fast-screening-of-c-sakazakii-in-formula-milk-powder
#11
JOURNAL ARTICLE
Yanying Wang, Ting Zheng, Xianming Li, Peng Wu
Cronobacter sakazakii ( C. sakazakii ) is a widely existing opportunistic pathogen and thus threatens people with low immunity, especially infants. To prevent the outbreak, a rapid and accurate on-site testing method is required. The current standard culture-based method is time-consuming (3-4 days), while the nucleic acid amplification (PCR)-based detection is mostly carried out in central laboratories. Herein, isothermal recombinase polymerase amplification (RPA) coupled with a photosensitization colorimetric assay (PCA) was adopted for the on-site detection of C...
March 28, 2024: Analytical Chemistry
https://read.qxmd.com/read/38546821/integration-of-a-fasting-mimicking-diet-programme-in-primary-care-for-type-2-diabetes-reduces-the-need-for-medication-and-improves-glycaemic-control-a-12-month-randomised-controlled-trial
#12
JOURNAL ARTICLE
Elske L van den Burg, Marjolein P Schoonakker, Petra G van Peet, Elske M van den Akker-van Marle, Hildo J Lamb, Valter D Longo, Mattijs E Numans, Hanno Pijl
AIMS/HYPOTHESIS: The aim of this study was to evaluate the impact on metabolic control of periodic use of a 5-day fasting-mimicking diet (FMD) programme as an adjunct to usual care in people with type 2 diabetes under regular primary care surveillance. METHODS: In this randomised, controlled, assessor-blinded trial, people with type 2 diabetes using metformin as the only glucose-lowering drug and/or diet for glycaemic control were randomised to receive 5-day cycles of an FMD monthly as an adjunct to regular care by their general practitioner or to receive regular care only...
March 28, 2024: Diabetologia
https://read.qxmd.com/read/38546706/evaluation-of-telehealth-services-that-are-clinically-appropriate-for-reimbursement-in-the-us-medicaid-population-mixed-methods-study
#13
JOURNAL ARTICLE
Sanjeev Saravanakumar, Andrey Ostrovsky
BACKGROUND: When the US Department of Health and Human Services instituted a State of Public Health Emergency (PHE) during the COVID-19 pandemic, many telehealth flexibilities were fast-tracked to allow state Medicaid agencies to reimburse new specialty services, sites of care, and mediums such as FaceTime to communicate with patients.. This resulted in expanded access to care for financially vulnerable Medicaid patients, as evidenced by an uptick in telehealth use. Research has mostly focused on telehealth reimbursement for limited use cases such as rural primary care, without broader consideration for how telehealth can be appropriately mainstreamed and maintained...
March 28, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38546632/machine-learning-aided-design-and-optimization-of-thermal-metamaterials
#14
REVIEW
Changliang Zhu, Emmanuel Anuoluwa Bamidele, Xiangying Shen, Guimei Zhu, Baowen Li
Artificial Intelligence (AI) has advanced material research that were previously intractable, for example, the machine learning (ML) has been able to predict some unprecedented thermal properties. In this review, we first elucidate the methodologies underpinning discriminative and generative models, as well as the paradigm of optimization approaches. Then, we present a series of case studies showcasing the application of machine learning in thermal metamaterial design. Finally, we give a brief discussion on the challenges and opportunities in this fast developing field...
March 28, 2024: Chemical Reviews
https://read.qxmd.com/read/38546439/electrochromic-devices-based-on-2d-moo-3-x-pedot-pss-composite-film-with-boosted-ion-transport
#15
JOURNAL ARTICLE
Haolin Yu, Huajing Fang, Kai Jing, Hailong Ma, Lingqi Wu, Yang Chai
Electrochromic materials allow for optical modulation and have attracted much attention due to their bright future in applications such as smart windows and energy-saving displays. Two-dimensional (2D) molybdenum oxide nanoflakes with combined advantages of high active specific surface area and natural layered structure should be highly potential candidates for electrochromic devices. However, the efficient top-down preparation of 2D MoO3 nanoflakes is still a huge challenge and the sluggish ionic kinetics hinder its electrochromic performance...
March 28, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38546423/antidiabetic-evaluation-of-kigelia-pinnata-root-bark-extract-in-streptozotocin-induced-type-2-diabetes-model-of-rats
#16
JOURNAL ARTICLE
Ravindra Kumar, Neeraj Kumar, Satyendra Kumar Rajput, Sudhanshu Mallan, Arun Kumar, Balwant Singh Rawat, Naresh Kumar Rangra, Shamsher Singh
Diabetes mellitus (DM) is the most common endocrine disorder characterized by increased blood glucose levels resulting from defective insulin secretion, resistance to insulin action, or both. DM is often associated with severe complications, and there is an increasing appreciation that cognitive function declines in DM. The aim of this research work was to evaluate Kigelia pinnata root bark extract in Streptozotocin (STZ)-induced type-2 diabetes. Experimental diabetes was induced by a single administration of STZ (60 mg/kg, intraperitoneal [i...
March 28, 2024: Assay and Drug Development Technologies
https://read.qxmd.com/read/38546310/a-case-report-of-unilateral-syphilitic-uveitis-a-diagnostic-challenge-and-the-role-of-point-of-care-ultrasound
#17
JOURNAL ARTICLE
Susana Gutierrez-Luke, Thijs Wolf, Kyle Green, Philip Graber
INTRODUCTION: Syphilis presents with diverse clinical manifestations, posing challenges for diagnosis, especially in the fast-paced emergency department (ED) setting. CASE REPORT: We report a rare case of unilateral syphilitic uveitis in an individual who had been sexually abstinent for 13 years. Using ocular point-of-care ultrasound in the ED, we successfully diagnosed this uncommon ocular manifestation. CONCLUSION: Our case highlights the diagnostic challenges of ocular syphilis and emphasizes the crucial nature of timely identification...
February 2024: Clinical Practice and Cases in Emergency Medicine
https://read.qxmd.com/read/38546276/isothermal-amplification-of-long-dna-fragments-at-low-temperature-by-improved-strand-displacement-amplification
#18
JOURNAL ARTICLE
Yinhua Zhang, Ashley N Luck, Nathan A Tanner
Strand displacement amplification (SDA) is an isothermal amplification technique wherein amplification of a nucleic acid is initiated by nicking enzyme activity at sites flanking the target. Diagnostic SDA is very fast but requires precise optimization and is limited to very short amplicons. Here we report an enhanced approach by addition of single-stranded DNA binding protein, crowding agents and dUTP to enable amplification of kilobase-length products at low temperatures. Additionally, we pair this improved SDA with a novel carryover contamination prevention, eliminating amplifiable DNA at the end of the reaction to reduce contamination risk...
March 28, 2024: BioTechniques
https://read.qxmd.com/read/38546251/fast-track-versus-conventional-perioperative-care-protocols-in-paediatric-intestinal-stoma-closure-%C3%A2-a-randomised-study
#19
JOURNAL ARTICLE
Tanzil Farhad, Md Khurshid Alam Sarwar, Mohammad Zonaid Chowdhury, Adnan Walid, Ayesha Sadia, Tanvir Kabir Chowdhury
BACKGROUND: It is still unclear to what extent fast-track (FT) surgery is applicable in paediatric surgery. The aim of the study was to compare the outcome between FT and conventional perioperative care protocols in paediatric intestinal stoma closure to assess the safety for future application. MATERIALS AND METHODS: This study was a prospective randomised study. Twenty-six paediatric patients who underwent intestinal stoma closure from December 2019 to March 2021 were divided into two groups: group A, conventional methods and Group B FT protocol...
April 1, 2024: African Journal of Paediatric Surgery: AJPS
https://read.qxmd.com/read/38546192/comparison-of-doppler-ultrasonic-sphygmomanometry-oscillometry-and-high-definition-oscillometry-for-non-invasive-blood-pressure-measurement-in-conscious-cats
#20
JOURNAL ARTICLE
Marieke Knies, Erik Teske, Hans Kooistra
OBJECTIVES: Systemic arterial hypertension is a common occurrence and can have serious adverse consequences in cats. Therefore, measuring blood pressure is very important. There are many indirect blood pressure measurement devices available. This study compared Doppler, oscillometric (petMAP Graphic II, SunTech Vet20, the Cardell Insight-X0000) and high-definition oscillometry devices for the non-invasive measurement of blood pressure in conscious cats. METHODS: In this prospective study, blood pressure was measured in 32 cats using the different devices according to the recommendations of the American College of Veterinary Internal Medicine Consensus Statement...
March 2024: Journal of Feline Medicine and Surgery
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