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https://www.readbyqxmd.com/read/28110158/general-distress-is-more-important-than-ptsd-s-cognition-and-mood-alterations-factor-in-accounting-for-ptsd-and-depression-s-comorbidity
#1
Brianna M Byllesby, Jon D Elhai, Marijo Tamburrino, Thomas H Fine, Gregory Cohen, Laura Sampson, Edwin Shirley, Philip K Chan, Israel Liberzon, Sandro Galea, Joseph R Calabrese
BACKGROUND: Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are highly comorbid and exhibit strong correlations with each other at both the symptom level and latent factor level. Various theories have attempted to explain this relationship. Results have been inconsistent regarding whether PTSD's negative alterations in cognition and mood factor (NACM) is significantly more related to depression, in contrast to other factors of PTSD. METHODS: Confirmatory factor analysis was used to attempt to address the relationships between PTSD and MDD in a large sample of trauma-exposed combat veterans from the Ohio National Guard as part of a larger longitudinal study...
January 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28110057/real-life-outcomes-for-patients-with-asthma-prescribed-spacers-for-use-with-either-extrafine-or-fine-particle-inhaled-corticosteroids
#2
Theresa W Guilbert, Gene Colice, Jonathan Grigg, Wim van Aalderen, Richard J Martin, Elliot Israel, Dirkje S Postma, Nicolas Roche, Wanda Phipatanakul, Elizabeth V Hillyer, Jennifer M Evans, Myrna B Dolovich, David B Price
BACKGROUND: Spacers are often used with pressurized metered-dose inhalers (pMDIs) to eliminate the need for coordinating inhalation with actuation. OBJECTIVE: To investigate the real-life effectiveness of spacers prescribed for use with either extrafine- or fine-particle inhaled corticosteroids (ICSs). METHODS: This historical matched cohort study examined anonymous medical record data over 2 years (1-year baseline, 1-year outcome) for patients with asthma aged 12 to 80 years initiating ICSs by pMDI with or without prescribed spacer...
January 18, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28109885/hetero-and-homodimerization-of-arabidopsis-thaliana-arginine-decarboxylase-atadc1-and-atadc2
#3
Israel Maruri-López, Juan F Jiménez-Bremont
The arginine decarboxylase enzyme (ADC) carries out the production of agmatine from arginine, which is the precursor of the first polyamine (PA) known as putrescine; subsequently, putrescine is turned into the higher PAs, spermidine and spermine. In Arabidopsis thaliana PA production occurs only from arginine and this step is initiated by two ADC paralogous, AtADC1 and AtADC2. PA production is essential for A. thaliana life cycle. Here, we analyzed the sub-cellular localization of AtADC1 and AtADC2 enzymes through GFP translational fusions...
January 18, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28108759/from-microhabitat-of-floral-nectar-up-to-biogeographic-scale-novel-insights-on-neutral-and-niche-bacterial-assemblies
#4
Yana Aizenberg-Gershtein, Ido Izhaki, Malka Halpern
Microbial model systems are very useful in addressing macro-ecological questions. Two major theories exist to date, to explain the community structure of organisms: (1) the dispersal (neutral) assembly theory which predicts that community similarity decreases with increasing geographic distance, independent of any environmental variables, and (2) the niche assembly theory which predicts that the communities' compositions are more homogeneous among sites characterized by similar environmental conditions. Our study system offered a unique opportunity to investigate the relative role of environmental conditions and spatial factors in shaping community composition...
January 20, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28108143/corrigendum-to-adrenomedullin-and-angiotensin-ii-signaling-pathways-involved-in-the-effects-on-cerebellar-antioxidant-enzymes-activity-brain-res-bull-128-2017-83-91
#5
Leticia Figueira, Anita Israel
No abstract text is available yet for this article.
January 17, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28107687/do-recreational-cannabis-users-unlicensed-and-licensed-medical-cannabis-users-form-distinct-groups
#6
Sharon R Sznitman
BACKGROUND: This study aims to gain a more nuanced perspective on the differences between recreationally and medically motivated cannabis use by distinguishing between people who use cannabis for recreational purposes, unlicensed and licensed medical users. METHODS: Data collection was conducted online from a convenience sample of 1479 Israeli cannabis users. Multinomial regression analysis compared unlicensed medical users (38%) with recreational (42%) and licensed medical (5...
January 17, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28107419/a-new-israeli-tobamovirus-isolate-infects-tomato-plants-harboring-tm-22-resistance-genes
#7
Neta Luria, Elisheva Smith, Victoria Reingold, Ilana Bekelman, Moshe Lapidot, Ilan Levin, Nadav Elad, Yehudit Tam, Noa Sela, Ahmad Abu-Ras, Nadav Ezra, Ami Haberman, Liron Yitzhak, Oded Lachman, Aviv Dombrovsky
An outbreak of a new disease infecting tomatoes occurred in October-November 2014 at the Ohad village in Southern Israel. Symptomatic plants showed a mosaic pattern on leaves accompanied occasionally by narrowing of leaves and yellow spotted fruit. The disease spread mechanically and rapidly reminiscent of tobamovirus infection. Epidemiological studies showed the spread of the disease in various growing areas, in the South and towards the Southeast and Northern parts of the country within a year. Transmission electron microscope (TEM) analysis showed a single rod-like form characteristic to the Tobamovirus genus...
2017: PloS One
https://www.readbyqxmd.com/read/28107026/impact-of-mobile-intensive-care-unit-use-on-total-ischemic-time-and-clinical-outcomes-in-st-elevation-myocardial-infarction-patients-real-world-data-from-the-acute-coronary-syndrome-israeli-survey
#8
Edward Koifman, Roy Beigel, Zaza Iakobishvili, Nir Shlomo, Yitschak Biton, Avi Sabbag, Elad Asher, Shaul Atar, Shmuel Gottlieb, Ronny Alcalai, Doron Zahger, Amit Segev, Ilan Goldenberg, Rafael Strugo, Shlomi Matetzky
BACKGROUND: Ischemic time has prognostic importance in ST-elevation myocardial infarction patients. Mobile intensive care unit use can reduce components of total ischemic time by appropriate triage of ST-elevation myocardial infarction patients. METHODS: Data from the Acute Coronary Survey in Israel registry 2000-2010 were analyzed to evaluate factors associated with mobile intensive care unit use and its impact on total ischemic time and patient outcomes. RESULTS: The study comprised 5474 ST-elevation myocardial infarction patients enrolled in the Acute Coronary Survey in Israel registry, of whom 46% ( n=2538) arrived via mobile intensive care units...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28106927/cationic-au-iii-versus-au-i-catalyst-controlled-divergent-reactivity-of-alkyne-tethered-lactams
#9
Pedro Almendros, Benito Alcaide, Sara Cembellín, Israel Fernández, Teresa Martínez Del Campo
Switchable reactivity through cationic gold-based catalyst control built on the oxidation state, namely cationic Au(III) versus Au(I), has been achieved in the direct functionalization of 2-azetidinone-tethered alkynyl indoles.
January 20, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28105299/geographic-variation-in-selected-hospital-procedures-and-services-in-the-israeli-health-care-system
#10
Joseph Mendlovic, Ethel-Sherry Gordon, Ziona Haklai, Jill Meron, Arnon Afek
BACKGROUND: Medical practice variation refers to differences in health service utilization among regions in the same country. It is used as a tool for studying health inequities. In 2011, the OECD launched a Medical Practice Variation Project which examines regional differences within countries and explores the sources of the inter-regional differences. The aim of this study is to examine the patterns and trends in geographic variation for selected health services in Israel. METHODS: The analysis is based on data from the National Hospital Discharges Database (NHDD) of the Israeli Ministry of Health...
2017: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/28104991/prevalence-of-hepatitis-c-virus-infection-among-hemodialysis-patients-in-the-middle-east-a-systematic-review-and-meta-analysis
#11
Soheil Ashkani-Esfahani, Seyed Moayed Alavian, Mohammad Salehi-Marzijarani
AIM: To determine hepatitis C virus (HCV) infection prevalence in each country of the Middle-East and the overall prevalence of the region. METHODS: In this systematic review, we gathered all documents related to HCV infection prevalence among hemodialysis patients in 17 middle-east countries from April 2006 to March 2016. We selected only cross-sectional studies that had proper sampling and measurement methods as well as a valid statistical analysis. RESULTS: After screening of 7311 documents, 56 studies were selected reporting the prevalence of HCV infection among hemodialysis patients from 10 countries of the region...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28104610/external-validation-and-comparison-of-three-prediction-tools-for-risk-of-osteoporotic-fractures-using-data-from-population-based-electronic-health-records-retrospective-cohort-study
#12
Noa Dagan, Chandra Cohen-Stavi, Maya Leventer-Roberts, Ran D Balicer
OBJECTIVE:  To directly compare the performance and externally validate the three most studied prediction tools for osteoporotic fractures-QFracture, FRAX, and Garvan-using data from electronic health records. DESIGN:  Retrospective cohort study. SETTING:  Payer provider healthcare organisation in Israel. PARTICIPANTS:  1 054 815 members aged 50 to 90 years for comparison between tools and cohorts of different age ranges, corresponding to those in each tools' development study, for tool specific external validation...
January 19, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28104565/matter-of-will-the-association-between-posttraumatic-stress-symptoms-and-the-will-to-live
#13
Yuval Palgi
The present study examined how posttraumatic-stress-symptoms presented after prolonged traumatic exposure to rocket attacks are related to the perception of the worthiness of life among individuals in the second half of their lives. Additionally, it was questioned whether the subjective evaluation of the time one has left to live affects this relationship. Using an in-region random digit dialing methodology, phone calls made to residents in the south of Israel, we sampled 339 community-dwelling older adults (age range 50-90; M=65...
January 10, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28104544/molecular-genetics-of-familial-hypercholesterolemia-in-israel-revisited
#14
Ronen Durst, Uche Ken Ibe, Shoshi Shpitzen, Daniel Schurr, Osnat Eliav, Marta Futema, Ros Whittall, Auryan Szalat, Vardiella Meiner, Hilla Knobler, Dov Gavish, Yaakov Henkin, Avishay Ellis, Ardon Rubinstein, Dror Harats, Rafael Bitzur, Bruno Hershkovitz, Steve E Humphries, Eran Leitersdorf
BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is an autosomal dominant disease caused by mutations in the genes for LDL receptor (LDLR), apolipoprotein B (APOB) and proprotein convertase subtilisin/kexin type9 (PCSK9). The purpose of the current investigation was to define the current spectrum of mutations causing FH in Israel. METHODS: New families were collected through the MEDPED (Make Early Diagnosis Prevent Early Death) FH program. Molecular analysis of the LDLR, PCSK9 and APOB genes was done using High Resolution Melt and direct sequencing in 67 index cases...
December 18, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/28104419/pelvic-hardware-eroding-into-the-bladder-a-rare-case-presentation-of-gross-hematuria-bladder-pain-and-refractory-luts
#15
Kristen E Gurtner, Jonathan A Israel, Michael R Pinsky, James F Mautner, June B Miguez, Daniel J Canter
We present a 60 year-old male who presented with gross hematuria, refractory lower urinary tract symptoms, and increasing bladder pain for 3 months. The patient had a prior history of a motorcycle accident and pelvic fracture requiring an extensive pelvic open reduction and internal fixation. During evaluation, the patient was found to have an orthopedic screw from his hardware eroding through the left lateral wall of his bladder and irritating his trigone. The patient underwent pelvic exploration with open cystotomy and hardware removal with the orthopedic service...
January 16, 2017: Urology
https://www.readbyqxmd.com/read/28104089/prediction-of-radiofrequency-ablation-lesion-formation-using-a-novel-temperature-sensing-technology-incorporated-in-a-force-sensing-catheter
#16
Guy Rozen, Leon Ptaszek, Israel Zilberman, Kevin Cordaro, E Kevin Heist, Christopher Beeckler, Andres Altmann, Zhang Ying, Zhenjiang Liu, Jeremy N Ruskin, Assaf Govari, Moussa Mansour
BACKGROUND: Real-time radiofrequency (RF) ablation lesion assessment is a major unmet need in cardiac electrophysiology. OBJECTIVE: The purpose of this study was to assess whether improved temperature measurement using a novel thermocoupling (TC) technology combined with information derived from impedance change, contact force (CF) sensing, and catheter orientation allows accurate real-time prediction of ablation lesion formation. METHODS: RF ablation lesions were delivered in the ventricles of 15 swine using a novel externally irrigated-tip catheter containing 6 miniature TC sensors in addition to force sensing technology...
February 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28103732/evaluation-of-antivenom-therapy-for-vipera-palaestinae-bites-in-children-experience-of-two-large-tertiary-care-pediatric-hospitals
#17
Dikla Pivko-Levy, Itamar Munchnak, Ayelet Rimon, Uri Balla, Dennis Scolnik, Christopher Hoyte, Yair Voliovitch, Miguel Glatstein
BACKGROUND: Antivenom has been successfully used to treat systemic and progressive, local manifestations of envenomation inflicted by Vipera (V.) palaestinae, the most common venomous snake in Israel. The objective of this study was to evaluate the fixed dose V. palaestinae monovalent (equine) immunoglobulin G antivenom used in two pediatric emergency departments. In particular, we wanted to assess the need for repeated antivenom administration and the rate of adverse antivenom effects in children...
January 20, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28103192/audio-visual-speaker-diarization-based-on-spatiotemporal-bayesian-fusion
#18
Israel Gebru, Sileye Ba, Xiaofei Li, Radu Horaud
Speaker diarization consists of assigning speech signals to people engaged in a dialogue. An audio-visual spatiotemporal diarization model is proposed. The model is well suited for challenging scenarios that consist of several participants engaged in multi-party interaction while they move around and turn their heads towards the other participants rather than facing the cameras and the microphones. Multiple-person visual tracking is combined with multiple speech-source localization in order to tackle the speech-to-person association problem...
January 5, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28102979/changes-in-salivary-cortisol-during-psychotherapy-for-posttraumatic-stress-disorder-a-pilot-study-in-30-veterans
#19
Sheila A M Rauch, Anthony P King, Israel Liberzon, Rebecca K Sripada
BACKGROUND: Convergent evidence suggests that the hypothalamic-pituitary-adrenal (HPA) axis is disrupted in posttraumatic stress disorder (PTSD) and that HPA axis normalization may be associated with symptom improvement. Thus, the current study was designed to test the association between HPA axis reactivity and treatment response in psychotherapy for PTSD. METHODS: Thirty returning veterans with DSM-IV-TR PTSD were randomly assigned to receive 10 sessions of prolonged exposure therapy or present-centered therapy as part of a previously published randomized clinical trial (2008-2010)...
January 17, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28102056/asthma-related-outcomes-in-patients-initiating-extrafine-ciclesonide-or-fine-particle-inhaled-corticosteroids
#20
Dirkje S Postma, Richard Dekhuijzen, Thys van der Molen, Richard J Martin, Wim van Aalderen, Nicolas Roche, Theresa W Guilbert, Elliot Israel, Daniela van Eickels, Javaria Mona Khalid, Ron M C Herings, Jetty A Overbeek, Cristiana Miglio, Victoria Thomas, Catherine Hutton, Elizabeth V Hillyer, David B Price
PURPOSE: Extrafine-particle inhaled corticosteroids (ICS) have greater small airway deposition than standard fine-particle ICS. We sought to compare asthma-related outcomes after patients initiated extrafine-particle ciclesonide or fine-particle ICS (fluticasone propionate or non-extrafine beclomethasone). METHODS: This historical, matched cohort study included patients aged 12-60 years prescribed their first ICS as ciclesonide or fine-particle ICS. The 2 cohorts were matched 1:1 for key demographic and clinical characteristics over the baseline year...
March 2017: Allergy, Asthma & Immunology Research
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