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https://www.readbyqxmd.com/read/28087547/risk-of-pneumonia-in-patients-with-isolated-minor-rib-fractures-a-nationwide-cohort-study
#1
Sai-Wai Ho, Ying-Hock Teng, Shun-Fa Yang, Han-Wei Yeh, Yu-Hsun Wang, Ming-Chih Chou, Chao-Bin Yeh
OBJECTIVES: Isolated minor rib fractures (IMRFs) after blunt chest traumas are commonly observed in emergency departments. However, the relationship between IMRFs and subsequent pneumonia remains controversial. This nationwide cohort study investigated the association between IMRFs and the risk of pneumonia in patients with blunt chest traumas. DESIGN: Nationwide population-based cohort study. SETTING: Patients with IMRFs were identified between 2010 and 2011 from the Taiwan National Health Insurance Research Database...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28087489/neurite-density-index-is-sensitive-to-age-related-differences-in-the-developing-brain
#2
Sila Genc, Charles B Malpas, Scott K Holland, Richard Beare, Timothy J Silk
PURPOSE: White matter development during childhood and adolescence is characterised by increasing white matter coherence and organisation. Commonly used scalar metrics, such as fractional anisotropy (FA), are sensitive to multiple mechanisms of white matter change and therefore unable to distinguish between mechanisms that change during development. We investigate the relationship between age and neurite density index (NDI) from neurite orientation dispersion and density imaging (NODDI), and the age-classification accuracy of NDI compared with FA, in a developmental cohort...
January 10, 2017: NeuroImage
https://www.readbyqxmd.com/read/28087388/unravelling-the-role-of-fatty-acid-metabolism-in-cancer-through-the-foxo3-foxm1-axis
#3
Paula Saavedra-García, Katie Nichols, Zimam Mahmud, Lavender Yuen-Nam Fan, Eric W-F Lam
Obesity and cachexia represent divergent states of nutritional and metabolic imbalance but both are intimately linked to cancer. There is an extensive overlap in their signalling pathways and molecular components involved such as fatty acids (FAs), which likely play a crucial role in cancer. Forkhead box (FOX) proteins are responsible of a wide range of transcriptional programmes during normal development, and the FOXO3-FOXM1 axis is associated with cancer initiation, progression and drug resistance. Free fatty acids (FFAs), FA synthesis and β-oxidation are associated with cancer development and progression...
January 10, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28086899/evaluations-of-diffusion-tensor-image-registration-based-on-fiber-tractography
#4
Yi Wang, Yu Shen, Dongyang Liu, Guoqin Li, Zhe Guo, Yangyu Fan, Yilong Niu
BACKGROUND: Diffusion Tensor Magnetic Resonance Imaging (DT-MRI, also known as DTI) measures the diffusion properties of water molecules in tissues and to date is one of the main techniques that can effectively study the microstructures of the brain in vivo. Presently, evaluation of DTI registration techniques is still in an initial stage of development. METHODS AND RESULTS: In this paper, six well-known open source DTI registration algorithms: Elastic, Rigid, Affine, DTI-TK, FSL and SyN were applied on 11 subjects from an open-access dataset, among which one was randomly chosen as the template...
January 10, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28081459/targeted-delivery-of-in-situ-pcr-amplified-sleeping-beauty-transposon-genes-to-cancer-cells-with-lipid-based-nanoparticle-like-protocells
#5
Kun Ma, Duo Fu, Dongli Yu, Changhao Cui, Li Wang, Zhaoming Guo, Chuanbin Mao
A Sleeping Beauty (SB) transposon system is made of a transposon plasmid (containing gene encoding a desired functional or therapeutic protein) and a transposase plasmid (encoding an enzyme capable of cutting and pasting the gene into the host cell genome). It is a kind of natural, nonviral gene delivery vehicle, which can achieve efficient genomic insertion, providing long-term transgenic expression. However, before the SB transposon system could play a role in promoting gene expression, it has to be delivered efficiently first across cell membrane and then into cell nuclei...
January 2, 2017: Biomaterials
https://www.readbyqxmd.com/read/28081037/higher-cd163-levels-are-associated-with-insulin-resistance-in-hepatitis-c-virus-infected-and-hiv-infected-adults
#6
Michael Reid, Yifei Ma, Rebecca Scherzer, Jennifer C Price, Audrey L French, Michael W Plankey, Carl Grunfeld, Phyllis C Tien
OBJECTIVES: HIV/hepatitis C virus (HCV) coinfection is associated with insulin resistance, but the mechanism is unclear. We hypothesized that intestinal epithelial damage and the consequent monocyte/macrophage activation and inflammation explain this perturbation. DESIGN: Cross-sectional study of 519 adults (220 HIV+/HCV-; 64 HIV-/HCV+; 89 HIV+/HCV+; 146 HIV-/HCV-). METHODS: We used multivariable linear regression to evaluate associations of HIV and HCV with the homeostasis model assessment of insulin resistance (HOMA-IR) and if intestinal fatty (FA) acid binding protein (I-FABP, a marker of gut epithelial integrity), soluble CD14 (sCD14) and soluble CD163 (sCD163) (markers of monocyte/macrophage activation), and IL-6 (an inflammatory cytokine) mediated this association...
January 28, 2017: AIDS
https://www.readbyqxmd.com/read/28079397/mixed-compared-with-single-source-proteins-in-high-protein-diets-affect-kidney-structure-and-function-differentially-in-obese-fa-fa-zucker-rats
#7
Jessay G Devassy, Jennifer L Wojcik, Naser H M Ibrahim, Peter Zahradka, Carla G Taylor, Harold M Aukema
Questions remain regarding the potential negative effects of dietary high protein (HP) on kidney health, particularly in the context of obesity in which the risk for renal disease is already increased. To examine whether some of the variability in HP effects on kidney health may be due to source of protein, obese fa/fa Zucker rats were given HP (35% of energy from protein) diets containing either casein, soy protein, or a mixed source of animal and plant proteins for 12 weeks. Control lean and obese rats were given diets containing casein at normal protein (15% of energy from protein) levels...
October 6, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28079361/controllable-synthesis-of-smart-multifunctional-nanoscal-metal-organic-framework-for-magnetic-resonance-optical-imaging-and-targeted-drug-delivery
#8
Xuechuan Gao, Manjue Zhai, Weihua Guan, Jingjuan Liu, Zhiliang Liu, Alatangaole Damirin
As a result of their extraordinarily large surfaces and well-defined pores, the design of multifunctional metal-organic framework (MOF) is crucial for drug delivery while has been rarely reported. In this paper, a novel drug delivery system (DDS) based on nanoscale metal-organic framework (MOF) was developed for using in cancer diagnosis and therapy. This MOF based tumour targeting DDS was fabricated by a simple post-synthetic surface modification process. Firstly, magnetic mesoporous nanomaterial Fe-MIL-53-NH2 was devoted for encapsulating the drug and served as a magnetic resonance (MR) contrast agent...
January 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28079023/incidence-and-growth-of-geographic-atrophy-during-5-years-of-comparison-of-age-related-macular-degeneration-treatments-trials
#9
Juan E Grunwald, Maxwell Pistilli, Ebenezer Daniel, Gui-Shuang Ying, Wei Pan, Glenn J Jaffe, Cynthia A Toth, Stephanie A Hagstrom, Maureen G Maguire, Daniel F Martin
PURPOSE: To estimate the incidence, size, and growth rate of geographic atrophy (GA) during 5 years of follow-up among participants in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). DESIGN: Cohort within a clinical trial. PARTICIPANTS: Participants included in CATT. METHODS: A total of 1185 CATT participants were randomly assigned to ranibizumab or bevacizumab treatment and to 3 treatment regimens...
January 2017: Ophthalmology
https://www.readbyqxmd.com/read/28078397/optimized-synthesis-of-novel-prenyl-ferulate-performed-by-feruloyl-esterases-from-myceliophthora-thermophila-in-microemulsions
#10
Io Antonopoulou, Laura Leonov, Peter Jütten, Gabriella Cerullo, Vincenza Faraco, Adamantia Papadopoulou, Dimitris Kletsas, Marianna Ralli, Ulrika Rova, Paul Christakopoulos
Five feruloyl esterases (FAEs; EC 3.1.1.73), FaeA1, FaeA2, FaeB1, and FaeB2 from Myceliophthora thermophila C1 and MtFae1a from M. thermophila ATCC 42464, were tested for their ability to catalyze the transesterification of vinyl ferulate (VFA) with prenol in detergentless microemulsions. Reaction conditions were optimized investigating parameters such as the medium composition, the substrate concentration, the enzyme load, the pH, the temperature, and agitation. FaeB2 offered the highest transesterification yield (71...
January 11, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28077731/%C3%AF-3-fatty-acid-supplementation-does-not-affect-autism-spectrum-disorder-in-children-a-systematic-review-and-meta-analysis
#11
Andrea Horvath, Jan Łukasik, Hania Szajewska
BACKGROUND: Effective treatments for the core symptoms of autism spectrum disorder (ASD) are still lacking. OBJECTIVE: We aimed to update the data on the effectiveness of ω-3 (n-3) fatty acid (FA) supplementation as a treatment for ASD. METHODS: The Cochrane Library, MEDLINE, and EMBASE databases were systematically searched up until August 2016, with no language restrictions for randomized controlled trials (RCTs) comparing ω-3 FA supplementation with placebo or with no supplementation...
January 11, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28077121/awareness-of-food-allergies-a-survey-of-pediatricians-in-kuwait
#12
Waleed Al-Herz, Khalid Husain, Ahmed Al-Khabaz, Mohamed A A Moussa, Fawaz Al-Refaee
BACKGROUND: Early diagnosis of food allergies (FA) is important for a favorable prognosis. This study aimed to determine the level of awareness of FA among pediatricians in Kuwait. METHOD: A 43-item self-administered questionnaire was designed and distributed to pediatricians working at 4 government hospitals in Kuwait. RESULTS: A total of 140 pediatricians completed the questionnaire, with a participation rate of 51.1% (81 males and 59 females)...
January 11, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28077028/ferulic-acid-suppresses-expression-of-tryptophan-metabolic-key-enzyme-indoleamine-2-3-dioxygenase-via-nf%C3%AE%C2%BAb-and-p38-mapk-in-lipopolysaccharide-stimulated-microglial-cells
#13
Manami Koshiguchi, Hitoshi Komazaki, Shizuka Hirai, Yukari Egashira
Ferulic acid (FA) is a phenol compound found in plants that has anti-inflammatory properties. Indoleamine 2, 3-dioxygenase (IDO) is a tryptophan catabolic enzyme induced in immune cells, including glial cells, during inflammation. Enhanced IDO expression leads to reduced tryptophan levels and increased levels of toxic metabolites, including quinolinic acid. Therefore, inhibition of IDO expression may be effective in suppressing progression of neurodegenerative diseases. In this study, we examined the effect of FA in microglial cells on IDO expression levels and related inflammatory signal molecules...
January 12, 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28076453/ferulic-acid-lowers-body-weight-and-visceral-fat-accumulation-via-modulation-of-enzymatic-hormonal-and-inflammatory-changes-in-a-mouse-model-of-high-fat-diet-induced-obesity
#14
T S de Melo, P R Lima, K M M B Carvalho, T M Fontenele, F R N Solon, A R Tomé, T L G de Lemos, S G da Cruz Fonseca, F A Santos, V S Rao, M G R de Queiroz
Previous studies have reported on the glucose and lipid-lowering effects of ferulic acid (FA) but its anti-obesity potential has not yet been firmly established. This study investigated the possible anti-obesitogenic effects of FA in mice fed a high-fat diet (HFD) for 15 weeks. To assess the antiobesity potential of FA, 32 male Swiss mice, weighing 20-25 g (n=6-8 per group) were fed a normal diet (ND) or HFD, treated orally or not with either FA (10 mg/kg) or sibutramine (10 mg/kg) for 15 weeks and at the end of this period, the body weights of animals, visceral fat accumulation, plasma levels of glucose and insulin hormone, amylase and lipase activities, the satiety hormones ghrelin and leptin, and tumor necrosis factor-α (TNF-α) and monocyte chemoattractant protein-1 (MCH-1) were analyzed...
January 5, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28074659/ferulic-acid-fa-abrogates-%C3%AE-radiation-induced-oxidative-stress-and-dna-damage-by-up-regulating-nuclear-translocation-of-nrf2-and-activation-of-nhej-pathway
#15
Ujjal Das, Krishnendu Manna, Amitava Khan, Mahuya Sinha, Sushobhan Biswas, Aaveri Sengupta, Anindita Chakraborty, Sanjit Dey
The present study was aimed to evaluate the radioprotective effect of ferulic acid (FA), a naturally occurring plant flavonoid in terms of DNA damage and damage related alterations of repair pathways by gamma radiation. FA was administered at a dose of 50 mg/kg body weight for five consecutive days prior to exposing the swiss albino mice to a single dose of 10 Gy gamma radiation. Ionising radiation induces oxidative damage manifested by decreased expression of Cu, Zn-SOD (SOD stands for super oxide dismutase), Mn-SOD and catalase...
January 11, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28074415/proceedings-of-r%C3%A3-animation-2017-the-french-intensive-care-society-international-congress
#16
Wulfran Bougouin, Eloi Marijon, Benjamin Planquette, Nicole Karam, Florence Dumas, David Celermajer, Daniel Jost, Lionel Lamhaut, Frankie Beganton, Alain Cariou, Guy Meyer, Xavier Jouven, Côme Bureau, Julien Charpentier, Omar Ben Hadj Salem, Lucie Guillemet, Michel Arnaout, Alexis Ferre, Guillaume Geri, Nicolas Mongardon, Frédéric Pène, Jean-Daniel Chiche, Jean-Paul Mira, Guylaine Labro, François Belon, Vinh-Phuc Luu, Julien Chenet, Guillaume Besch, Marc Puyraveau, Gaël Piton, Gilles Capellier, Maëlle Martin, Jean-Baptiste Lascarrou, Aurélie Le Thuaut, Jean-Claude Lacherade, Laurent Martin-Lefèvre, Maud Fiancette, Isabelle Vinatier, Christine Lebert, Konstantinos Bachoumas, Aihem Yehia, Matthieu Henry-Laguarrigue, Gwenhaël Colin, Jean Reignier, Elodie Privat, Joséphine Escutnaire, Cyrielle Dumont, Valentine Baert, Christian Vilhelm, Hervé Hubert, Vincent Robert-Edan, Karim Lakhal, Andrew Quartin, Brian Hobbs, Cynthia Cely, Cynthia Bell, Tai Pham, Roland Schein, Yimin Geng, Chaan Ng, Stephan Ehrmann, Charlotte Salmon Gandonnière, Julie Boisramé-Helms, Olivier Le Tilly, Isabelle Benz De Bretagne, Emmanuelle Mercier, Julie Mankikian, Anne Bretagnol, Ferhat Meziani, Jean Michel Halimi, Chantal Barin Le Guellec, Stéphane Gaudry, David Hajage, Florence Tubach, Bertrand Pons, Eric Boulet, Alexandre Boyer, Guillaume Chevrel, Nicolas Lerolle, Dorothée Carpentier, Nicolas de Prost, Alexandre Lautrette, Julien Mayaux, Saad Nseir, Jean-Damien Ricard, Didier Dreyfuss, René Robert, Franscesco Garzotto, Eric Kipnis, Ciro Tetta, Claudio Ronco, David Schnell, Bourmaud Aurelie, Marie Reynaud, Christophe Clec'h, Mourad Benyamina, François Vincent, Christophe Mariat, Caroline Bornstain, Stephane Rouleau, Christophe Leroy, Yves Cohen, Jerome Morel, Matthieu Legrand, Jeremy Terreaux, Michaël Darmon, Marie Cantier, Adeline Morisot, Emmanuel Guérot, Emmanuel Canet, Etienne De Montmollin, Guillaume Voiriot, Mathilde Neuville, Jean-François Timsit, Romain Sonneville, Abdallah Fayssoil, Tania Stojkovic, Anthony Behin, Adam Ogna, Frédéric Lofaso, Pascal Laforet, Karim Wahbi, Helene Prigent, Denis Duboc, David Orlikowski, Bruno Eymard, Djillali Annane, Loic Le Guennec, Clémentine Cholet, Nicolas Bréchot, Guillaume Hekimian, Sébastien Besset, Guillaume Lebreton, Ania Nieszkowska, Jean Louis Trouillet, Pascal Leprince, Alain Combes, Charles-Edouard Luyt, Marion Griton, Musa Sesay, Nadia Sibaï De Panthou, Thomas Bienvenu, Matthieu Biais, Karine Nouette-Gaulain, Guillaume Fossat, Florian Baudin, Cécile Coulanges, Sabrine Bobet, Arnaud Dupont, Léa Courtes, Dalila Benzekri, Toufik Kamel, Grégoire Muller, Nicolas Bercault, François Barbier, Isabelle Runge, Marie Skarzynski, Armelle Mathonnet, Thierry Boulain, Youenn Jouan, Noémie Teixera, Claire Hassen-Khodja, Antoine Guillon, Christophe Gaborit, Leslie Grammatico-Guillon, Cécile Rebière, Elie Azoulay, Benoit Misset, Stephane Ruckly, Maïté Garrouste-Orgeas, Nancy Kentish-Barnes, Jacques Duranteau, Marie Thuong, Liliane Joseph, Anne Renault, Olivier Lesieur, Anne-Gaelle Si Larbi, Gérald Viquesnel, Benjamin Zuber, Sophie Marque, Stanislas Kandelman, Nicolas Pichon, Bernard Floccard, Marion Galon, Sylvie Chevret, Nancy Kentish-Barnes, Valérie Seegers, Stéphane Legriel, Samir Jaber, Jean Yves Lefrant, Danielle Reuter, Olivier Guisset, Christophe Cracco, Amélie Seguin, Jacques Durand-Gasselin, Marine Thirion, Zoé Cohen-Solal, Hélène Foulgoc, Julien Rogier, Elsa Delobbe, Frédérique Schortgen, Pierre Asfar, Boisramé-Helms Julie, David Grimaldi, Grelon Fabien, Nadia Anguel, Lasocki Sigismond, Henry-Lagarrigue Matthieu, Frédéric Gonzalez, Legay François, Christophe Guitton, Maleka Schenck, Doise Jean-Marc, Peter Radermacher, Nancy Kentish-Barnes, Joseph Nsiala Makunza, Mejeni Kamdem Nathalie, Akilimali Pierre, Kilembe Manzanza Adolphe, Rafael Mahieu, Thomas Reydel, Angéline Jamet, Nicolas Chudeau, Julien Huntzinger, Steven Grange, Anne Courte, Jérémie Lemarie, Sébastien Gibot, Julia Champey, Jean Dellamonica, Damien Du Cheyron, Damien Contou, Jean-Marc Tadié, Martin Cour, Gaetan Beduneau, Antoine Marchalot, Laurent Guérin, Sebastien Jochmans, Nicolas Terzi, Sebastien Preau, Christian Brun-Buisson, Armand Mekontso Dessap, Meryl Vedrenne-Cloquet, Sophie Breinig, Camille Jung, Maxime Brussieux, Marie-Odile Marcoux, Xavier Durrmeyer, Renaud Blondé, François Angoulvant, Jérôme Grasset, Jérôme Naudin, Stéphane Dauger, Solenn Remy, Karine Kolev-Descamp, Julie Demaret, Guillaume Monneret, Etienne Javouhey, Maryline Chomton, Michaël Sauthier, Emilie Vallieres, Philippe Jouvet, Guillaume Geslain, Isabelle Guellec, Jérôme Rambaud, Matthieu Schmidt, Peter Schellongowski, Amandine Dorget, Nicolo Patroniti, Fabio Silvio Taccone, Dinis Reis Miranda, Jean Reuter, Hélène Prodanovic, Marc Pierrot, Martin Balik, Sunghoon Park, Claude Guérin, Laurent Papazian, Reignier Jean, Louis Ayzac, Anderson Loundou, Jean-Marie Forel, Mehdi Mezidi, Mylène Aublanc, Sophie Perinel-Ragey, Floriane Lissonde, Aurore Louf-Durier, Romain Tapponnier, Hodane Yonis, Remi Coudroy, Jean-Pierre Frat, Florence Boissier, Arnaud W Thille, Flore Richard, Hélène Le Gullou-Guillemette, Jonathan Fahri, Achille Kouatchet, Laetitia Bodet-Contentin, Denis Garot, Déborah Le Pennec, Laurent Vecellio, Elsa Tavernier, Pierre François Dequin, Jonathan Messika, Yolaine Martin, Natacha Maquigneau, Christelle Puechberty, Annabelle Stoclin, Serge Villard, Aline Dechanet, Audrey De Jong, Marion Monnin, Mehdi Girard, Gérald Chanques, Nicolas Molinari, Maxens Decavèle, Sébastien Campion, Roukia Ainsouya, Marie-Cécile Niérat, Mathieu Raux, Thomas Similowski, Alexandre Demoule, Keyvan Razazi, Martial Tchir, Faten May, Guillaume Carteaux, Rougevin-Baville Pauline, Andronikof Marc, Jean Pierre Bedos, Koukabi Mehrsa, Carole Mauger-Briche, François Mijon, Pierre Trouiller, Benjamin Sztrymf, Pierre Cretallaz, Romain Mermillod-Blondin, Dominique Savary, Ines Sedghiani, Hamdi Doghri, Asma Jendoubi, Dhekra Hamdi, Mohamed Ali Cherif, Youssef Zied El Hechmi, Jerbi Zouheir, Nicolas Persico, Francois Maltese, Cécile Ferrigno, Amandine Bablon, Cécile Marmillot, Antoine Roch, Ines Sedghiani, Grégory Papin, Marc Gainnier, Laurent Argaud, Adrie Christophe, Bertrand Souweine, Dany Goldgran-Toledano, Guillaume Marcotte, Anne Sylvie Dumenil, Schwebel Carole, Jerôme Cecchini, Samuel Tuffet, Muriel Fartoukh, Damien Roux, Martial Thyrault, Mekontso Dessap Armand, Simon Chauveau, Nadège Wesner, Laurence Monnier-Cholley, Naïke Bigé, Hafid Ait-Oufella, Bertrand Guidet, Vincent Dubée, Pierre Labroca, Jérémie Lemarié, Gérard Chiesa, Isabelle Laroyenne, Léo Borrini, Rémi Klotz, Quoc Phan Sy, Marie-Christine Cristina, Jean Paysant, Pierre Fillâtre, Arnaud Gacouin, Matthieu Revest, Pierre Tattevin, Erwan Flecher, Yves Le Tulzo, Matthieu Jamme, Fabrice Daviaud, Nathalie Marin, Michael Thy, Baptiste Duceau, Fanny Ardisson, Valade Sandrine, Marion Venot, Benoît Schlemmer, Lara Zafrani, Stéphanie Pons, Lenka Styfalova, Lila Bouadma, Aguila Radjou, Jordane Lebut, Bruno Mourvillier, Richard Dorent, Marie-Pierre Dilly, Patrick Nataf, Michel Wolff, Aëlle Le Gall, Simon Bourcier, Yacine Tandjaoui-Lambiotte, Vincent Das, Mikael Alves, Naïke Bigé, Chtara Kamilia, Ammar Rania, Najeh Baccouch, Olfa Turki, Hmida Chokri Ben, Mabrouk Bahloul, Mounir Bouaziz, Claire Dupuis, Anne Perozziello, Julien Letheulle, Marc Valette, Cécile Herrmann-Storck, Laura Crosby, Khalid Elkoun, Benjamin Madeux, Frédéric Martino, Hélène Migueres, Pascale Piednoir, Matthias Posch, Guillaume Thiery, Minh-Tu Huynh-Ky, Pierre Alexandre Bouchard, Jean-François Sarrazin, François Lellouche, Mai-Anh Nay, Brice Lortat-Jacob, Bertrand Rozec, Marion Colnot, Nicolas Belin, Loïc Barrot, Jean-Christophe Navellou, Cyrille Patry, Claire Chaignat, Melanie Claveau, Frédéric Claude, Cécile Aubron, Zoe Mcquilten, Michael Bailey, Jasmin Board, Heidi Buhr, Bruce Cartwright, Mark Dennis, Paul Forrest, Carol Hodgson, David Mcilroy, Deirdre Murphy, Lynnette Murray, Vincent Pellegrino, David Pilcher, Jayne Sheldrake, Huyen Tran, Shirley Vallance, Jamie Cooper, Camille Bombled, Charles Vidal, Dimitri Margetis, Julien Amour, Domien Coart, Jasperina Dubois, Tom Van Herpe, Dieter Mesotten, Sébastien Bailly, Jc Lucet, Alain Lepape, François L'hériteau, Martine Aupée, Caroline Bervas, Sandrine Boussat, Anne Berger-Carbonne, Anaïs Machut, Anne Savey, Jean-Jacques Tudesq, Sandrine Valade, Lionel Galicier, Cédric De Bazelaire, Nicolas Munoz-Bongrand, Xavier Mignard, Lucie Biard, Djamel Mokart, Martine Nyunga, Fabrice Bruneel, Antoine Rabbat, Pierre Perez, Anne Pascale Meert, Dominique Benoit, Eric Mariotte, Franck Ehooman, Rebecca Hamidfar-Roy, Yannick Hourmant, Arnaud Mailloux, Alexandra Beurton, Jean-Louis Teboul, Valentina Girroto, Galarza Laura, Christian Richard, Xavier Monnet, Vincent Dubée, Hamid Merdji, Julien Dang, Gabriel Preda, Jean-Luc Baudel, Cyrielle Desnos, Michel Zeitouni, Ines Belaroussi, Antoine Parrot, Clarisse Blayau, Jean-Pierre Fulgencio, Christophe Quesnel, Vincent Labbe, Marc Pineton De Chambrun, François Beloncle, Sybille Merceron, Yannick Fedun, Bernard Lecomte, Jérôme Devaquet, Marc Puidupin, Bruno Verdière, Zahir Amoura, Constance Vuillard, Jais Xavier, Delphine Bourlier, Amar David, Sattler Caroline, Montani David, Simmoneau Gerald, Sitbon Olivier, Marc Humbert, Savale Laurent, Olivier Dujardin, Adrien Bouglé, Hamou Nora Ait, Joe Elie Salem, Najoua El-Helali, Zoé Coppere, Aude Gibelin, Clementine Taconet, Michel Djibre, Adel Maamar, Elen Colobert, Pierre Fillatre, Fabrice Uhel, Christophe Camus, Josquin Moraly, Redouane Dahoumane, Eric Maury, Boun Kim Tan, Vivier Emmanuel, Misslin Pauline, Parmeland Laurence, Poirié Philippe, Jean-Ralph Zahar, Haond Catherine, Pommier Christian, Ait-Bouziad Karim, Hocine Mounia, Témime Laura, Vero Hanitra Rasoldier, Guy Mager, Jean-Pierre Eraldi, Stéphanie Gelinotte, François Bougerol, Julien Dehay, Jean-Philippe Rigaud, Pierre Louis Declercq, Julien Michel, Nejla Aissa, Sandrine Henard, Philippe Guerci, Ichraq Latar, Bruno Levy, Nicolas Girerd, Antoine Kimmoun, Saousen Ben Abdallah, Sabrine Nakaa, Kmar Hraiech, Dhouha Ben Braiek, Ali Adhieb, Abdelwaheb M'ghirbi, Ali Ousji, Zeineb Hammouda, Fekri Abroug, Walid Sellami, Zied Hajjej, Walid Samoud, Iheb Labbene, Mustapha Ferjani, Fatma Kaaniche Medhioub, Rania Allela, Najla Ben Algia, Samar Cherif, Delphine Attia, Andrianjafy Herinjatovo, Xavier Laborne Francois, Med Aziz Bouhouri, Mohamed Taoufik Slaoui, A Soufi, K Khaleq, D Hamoudi, A Nsiri, R Harrar, Eric Maury, Suzanne Goursaud, Maxime Gauberti, Paul-Emile Labeyrie, Thomas Gaberel, Véronique Agin, Eric Maubert, Denis Vivien, Clément Gakuba, Anwar Armel, Rchi Abdou, Samira Kalouch, Khalid Yaqini, Aziz Chlilek, Walid Sellami, Soumaya Ben Yedder, Alexandre Tonnelier, Fabien Hervé, Guillaume Halley, Jean-Luc Frances, Mickael Moriconi, Mathieu Saoli, Aude Garnero, Didier Demory, Jean Michel Arnal, Bertrand Canoville, Cédric Daubin, Jennifer Brunet, Hassen Ben Ghezala, Salah Snouda, Chiekh Imen Ben, Moez Kaddour, Islem Ouanes, Mahdi Marzouk, Françoise Haniez, Hélène Jaillet, Henri Maas, Pierre Andrivet, Christian Darné, François Viau, Hassen Ben Ghezala, Islem Ouanes, Laurence Dangers, Claire Montlahuc, Sébastien Perbet, Islem Ouanes, Zeineb Hamouda, Sabrine Nakee, Lamia Ouanes-Besbes, Khaoula Meddeb, Ahmed Khedher, Nesrine Sma, Jihene Ayachi, Messaouda Khelfa, Nesrine Fraj, Hend Ben Lakhal, Hedia Hammed, Raja Boukadida, Hajer Hafsa, Imed Chouchene, Mohamed Boussarsar, Braiek Dhouha Ben, Lamia Ouanes-Besbes, Kaoutar Benatti, A Dafir, W Aissaoui, W Elallame, W Haddad, R Cherkab, C Elkettani, L Barrou, Zakaria Ait Hamou, Xavier Repessé, Cyril Charron, Alix Aubry, Alexis Paternot, Julien Maizel, Michel Slama, Antoine Vieillard-Baron, Ahlem Trifi, Sami Abdellatif, Meriem Fatnassi, Foued Daly, Rochdi Nasri, Khaoula Ben Ismail, Salah Ben Lakhal, Florian Bazalgette, Aurelien Daurat, Claire Roger, Laurent Muller, Denis Doyen, Rémi Plattier, Alexandre Robert, Hervé Hyvernat, Gilles Bernardin, Mathieu Jozwiak, Julia Gimenez, Pablo Mercado, François Depret, Najla Tilouch, Houda Mater, Ben Sik Ali Habiba, Oussama Jaoued, Rim Gharbi, Mohamed Fekih Hassen, Souheil Elatrous, Pierre Pasquier, Quentin Vuillemin, Jean-Vivien Schaal, Thibault Martinez, Sandrine Duron, Marion Trousselard, Pierre-Eric Schwartzbrod, Thomas Baugnon, Laurent Dupic, Caroline Duracher Gout, Laure De Saint Blanquat, Sylvie Séguret, Gaelle Le Ficher, Gilles Orliaguet, Philippe Hubert, Naïke Bigé, Guillaume Leblanc, Raphael Briand, Lucas Brousse, Valentine Brunet, Léonard Chatelain, Dominique Prat, Frédéric Jacobs, Nadège Demars, Olfa Hamzaoui, Guy Moneger, Benjamin Sztrymf, Emilie Duburcq-Gury, Léa Satre-Buisson, Thibault Duburcq, Julien Poissy, Laurent Robriquet, Merce Jourdain, Thierry Sécheresse, Mattéo Miquet, Alexis Simond, Pascal Usseglio, Yamina Hamdaoui, Mohamed Boussarsar, Victoire Desailly, Patrick Brun, Pauline Iglesias, Jérémie Huet, Clémence Masseran, Antoine Claudon, Clément Ebeyer, Thomas Truong, Antoine Tesnière, Alexandre Mignon, Stéphane Gaudry, Dabor Resiere, Ruddy Valentino, Julien Fabre, Benoit Roze, Jean-Louis Ferge, Cyrille Charbatier, Sabia Marie, Michel Scholsser, Signate Aitsatou, Mathieu Raad, Andre Cabie, Hossein Mehdaoui, Clement Cousin, Christophe Rousseau, Jean-François Llitjos, Fanny Alby-Laurent, Julie Toubiana, Nadia Belaidouni, Marlène Cherruault, Jérome Tamburini, Didier Bouscary, Sarah Fert, Eugénie Delile, Emmanuel Besnier, David Coquerel, Rémi Nevière, Vincent Richard, Fabienne Tamion, Chaojie Wei, Huguette Louis, Schmitt Margaux, Albuisson Eliane, Orlowski Sophie, Antoine Kimmoun, Zakaria Riad, Marine Coroir, Bernard Rémy, Bombled Camille, Jeremie Joffre, Philippe Aegerter, Dejan Ilic, Marc Ginet, Caroline Pignard, Philippe Nguyen, Guillaume Mourey, Emmanuel Samain, Sebastien Pili-Floury, Romain Jouffroy, Caill Nicolas, Jean-Claude Alvarez, Maraffi Tomasso, Pascal Philippe, Jean-Herlé Raphalen, J Baud Frédéric, Benoit Vivien, Carli Pierre, Frederic Baud, Hana Fredj, Youssef Blel, Nozha Brahmi, Hassen Ben Ghezala, Anne-Sophie Hanak, Isabelle Malissin, Joel Poupon, Patricia Risede, Lucie Chevillard, Bruno Megarbane, Manel Barghouth, Aymen M'rad, Marwa Ben Hmida, Hafedh Thabet, Hao Liang, Jacques Callebert, Camille Lagard, Bruno Megarbane, Sahar Habacha, Bassem Chatbri, Christophe Camillerapp, Laurence Labat, Marion Soichot, Pierre Garçon, Antoine Goury, Lamia Kerdjana, Sebastian Voicu, Nicolas Deye, Bruno Megarbane, Anwar Armel, Benqqa Anas, Mezgui Othman, S Moumine, S Kalouch, K K Yakini, A Chlilek, Ahmed Hajji, Assaad Louati, Ammar Khaldi, Aida Borgi, Nargess Ghali, Asma Bouziri, Khaled Menif, Jaballah Najla Ben, Anwar Armel, Jeanne Brochon, Mihaela Dumitrescu, Sarah Thévenot, Jean-Pascal Saulnier, Khaled Husseini, Catherine Laland, Julie Cremniter, Anne Bousseau, Olivier Castel, Cassandra Brémaud-Csizmadia, Margot Diss, Aurélie Portefaix, Julien Berthiller, Yves Gillet, Nabil Tabet Aoul, Ali Douah, Zakaria Addou, Houari Youbi, Mohamed Moussati, Kamel Belhabiche, Souad Mir, Sanaa Abada, Zerhouni Amel, Nabil Aouffen, Zina Bouzit, Ahmed H Grati, Gilles F Dhonneur, Mohamed Boussarsar, Nicolas Lau, Ilham Mezhari, Nicolas Roucaud, Matthieu Le Meur, Rémi Paulet, Jean-Michel Coudray, Wahiba Imène Ghomari, Reda Boumlik, Vincent Peigne, Jean-Louis Daban, Mathieu Boutonnet, Bernard Lenoir, Hafiani Yassine, Cheikh Chaigar Mohamed, Allali Khalid, Moussaid Ihssan, Elyoussoufi Said, Salmi Said, Amira Ben Jazia, Jaziri Fatima, Skouri Wafa, Bennasr Maha, Ben Abdelghni Khaoula, Turki Sami, B Abdallah Taeib, Fatma Kaaniche Medhioub, Virginie Rollet-Cohen, Philippe Sachs, Zied Merchaoui, Sylvain Renolleau, Mehdi Oualha, Maxime Eloi, Sandrine Jean, Maryne Demoulin, Cécile Valentin, Julia Guilbert, Hervé Walti, Ricardo Carbajal, Pierre-Louis Leger, Yasemin Karaca-Altintas, Astrid Botte, Julien Labreuche, Elodie Drumez, Patrick Devos, Franck Bour, Francis Leclerc, Ayari Ahmed, Menif Khaled, Assaad Louati, Borgi Aida, Khaldi Ammar, Ghali Narjess, Hajji Ahmed, Bouziri Asma, Nejla Ben Jaballah, Pierre-Louis Leger, Julien Pansiot, Valérie Besson, Bruno Palmier, Olivier Baud, Bruno Cauli, Christiane Charriaut-Marlangue, Amélie Mansuy, Fabrice Michel, Stéphane Le Bel, Julia Boubnova, Fabrice Ughetto, Caroline Ovaert, Virginie Fouilloux, Olivier Paut, Matthias Jacquet-Lagrèze, Nicolas Tiebergien, Najib Hanna, Jean-Noël Evain, Florent Baudin, Sonia Courtil-Teyssedre, Dominique Bompard, Marc Lilot, Laurent Chardonal, Jean-Luc Fellahi, Claire Claverie, Guillaume Pouessel, Aimée Dorkenoo, Jean-Marie Renaudin, Mireille Eb, Antoine Deschildre, Stéphane Leteurtre, Hafiani Yassine, Belkadi Kamal, Oboukhlik Adil, Aalalam Ouafa, Moussaoui Mouhamed, Charkab Rachid, Barrou Lahoucine, Fahmi Dachraoui, Sabrine Nakkaa, Hammouda Zaineb, Dorra Mlika, Olfa Gloulou, Mohamed Boussarsar, Setti-Aouicha Zelmat, Djamila-Djahida Batouche, Belkacem Chaffi, Fatima Mazour, Nadia Benatta, Ines Fathallah, Rafaa Aloui, Aymen Zoubli, Nadia Kouraichi, Ines Fathallah, N Kouraichi, Shireen Salem, Eric Vicaut, Bruno Megarbane, David Ambroise, Anne-Marie Loriot, Emmanuel Bourgogne, Bruno Megarbane, Hatem Ghadhoune, Guissouma Jihene, Insaf Trabelsi, Hend Allouche, Habib Brahmi, Mohamed Samet, Hatem El Ghord, Rodolphe Lebeau, Jean-Louis Laplanche, Nadia Benturquia, Bruno Megarbane, Youssef Blel, A M'rad, Fatma Essafi, A Benabderrahim, Romain Jouffroy, Dabor Resiere, Bruno Sanchez, Jocelyn Inamo, Bruno Megarbane, Djamila-Djahida Batouche, Amel Zerhouni, Kheira Tabeliouna, Amine Negadi, Zahia Mentouri, Fanny Le Gall, Jean-Luc Hanouz, Hervé Normand, Abdo Khoury, Fatimata Seydou Sall, Alban De Luca, Aurore Pugin, Lionel Pazart, Chrystelle Vidal, Franck Leroux, Abdo Khoury, Erwan L'Her, Nicolas Marjanovic, Abdo Khoury, Thibault Desmettre, Christophe Lambert, Sophie Perinel Ragey, Loredana Baboi, Jean-Etienne Bazin, Catherine Koffel, Gilles Dhonneur, Zina Bouzit, Larbi Bradai, Issam Ben Ayed, Fethi Aissa, Hakim Haouache, Yoann Marechal, Patrick Biston, Michael Piagnerelli, Perrine Bortolotti, Delphine Colling, Vincent Colas, Benoit Voisin, Florent Dewavrin, Thierry Onimus, Patrick Girardie, Fabienne Saulnier, Tomas Urbina, Yann Nguyen, Anne-Lise Druoton, Marc Soudant, Damien Barraud, Marie Conrad, Aurélie Cravoisy-Popovic, Lionel Nace, Pierre-Edouard Bollaert, Ruste Martin, Laurent Bitker, Jean-Christophe Richard, David Brossier, Isabelle Goyer, Christopher Marquis, Marie Lampin, Alain Duhamel, Hélène Béhal, Tahar Dhaoui, Véronique Godeffroy, Eve Devouge, Dominique Evrard, Florence Delepoulle, Sylvie Racoussot, Bruno Grandbastien, Marie Lampin, Claire Heilbronner, Emeline Roy, Alexandra Masson, Alice Hadchouel-Duvergé, Virginie Rigourd, Elise Delacroix, Isabelle Wroblewski, Isabelle Pin, Anne Ego, Valerie Payen, Thierry Debillon, Anne Millet, Julien Denot, Véronique Berthelot, Emilie Thueux, Marie Reymond, Alexandra De Larrard, Alain Amblard, Pierre-Louis Leger, Nabil Tabet Aoul, Virginie Lemiale, Johanna Oziel, Noelle Brule, Anne-Sophie Moreau, Takoua Marhbène, Salma Sellami, Amira Jamoussi, Samia Ayed, Emna Mhiri, Leila Slim, Jalila Ben Khelil, Mohamed Besbes, Sylvain Chawki, Aicha Hamdi, Magali Ciroldi, Alice Cottereau, Edouard Obadia, Yoann Zerbib, Claire Andrejak, Sylvie Ricome, Hervé Dupont, François Baudin, Pauline Dureau, Audrey Tanguy, Charlotte Arbelot, Hassen Kais Ben, Ahmed Charfeddine, Benjamin Granger, Lucile Laporte, Coralie Hermetet, Kais Regaieg, Rim Khemakhem, Hedi Chelly, Chaigar Mohammed Cheikh, Hamid Mountij, Kawtar Rghioui, Wafae Haddad, Rachid Cherkab, Houcine Barrou, Aitmouden Naima, Othmani M Bennani, Kais Regaieg, Ahmed Douib, Amal Samet, Pierre-Julien Cungi, Cédric Nguyen, Jean Cotte, Erwan D'aranda, Eric Meaudre, Jean-Phillipe Avaro, Mohamed Taoufik Slaoui, Amel Mokline, Imene Rahmani, Achraf Laajili, Helmi Amri, Lazheri Gharsallah, Bahija Gasri, Sofiene Tlaili, Rym Hammouda, Amen Allah Messadi
No abstract text is available yet for this article.
January 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28074362/the-determination-and-fate-of-disinfection-by-products-from-ozonation-chlorination-of-fulvic-acid
#17
Xin Zhong, Chongwei Cui, Shuili Yu
Ozonation of fulvic acid (FA) can result in diverse intermediate oxidation by-products, significantly affecting disinfection by-product (DBP) formation following chlorination. The objective of this study was to provide insight into ozone reaction intermediates and reveal the possible formation pathway of DBPs from ozonation of FA due to the formation of intermediate oxidation by-products. Aldehydes, aromatic acids, short-chain acids, chloroform, and dichloroacetic acid were detected at various ozone dosage additions...
January 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28073680/rationale-and-design-of-pemvitastart-an-open-label-randomized-trial-comparing-simultaneous-versus-standard-initiation-of-vitamin-b12-and-folate-supplementation-in-nonsquamous-non-small-cell-lung-cancer-patients-undergoing-first-line-pemetrexed-based-chemotherapy
#18
Milind Baldi, Digambar Behera, Jyotdeep Kaur, Rakesh Kapoor, Navneet Singh
Pemetrexed is the preferred chemotherapeutic drug for nonsquamous, non-small-cell lung cancer patients whenever the predictive molecular biomarkers for targeted therapy have either not been assessed or are absent. As per manufacturers' instructions, supplementation with folic acid (FA; folate) at a dose of 350 to 1000 μg daily should be started seven days before the first dose of pemetrexed-based chemotherapy and continued during therapy and for 21 days after therapy cessation. Vitamin B12 injections (1000 μg intramuscularly) should also be started one week before the first dose of chemotherapy...
December 2, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28072829/predicting-the-metabolic-sites-by-flavin-containing-monooxygenase-on-drug-molecules-using-svm-classification-on-computed-quantum-mechanics-and-circular-fingerprints-molecular-descriptors
#19
Chien-Wei Fu, Thy-Hou Lin
As an important enzyme in Phase I drug metabolism, the flavin-containing monooxygenase (FMO) also metabolizes some xenobiotics with soft nucleophiles. The site of metabolism (SOM) on a molecule is the site where the metabolic reaction is exerted by an enzyme. Accurate prediction of SOMs on drug molecules will assist the search for drug leads during the optimization process. Here, some quantum mechanics features such as the condensed Fukui function and attributes from circular fingerprints (called Molprint2D) are computed and classified using the support vector machine (SVM) for predicting some potential SOMs on a series of drugs that can be metabolized by FMO enzymes...
2017: PloS One
https://www.readbyqxmd.com/read/28072689/an-observational-study-on-the-effect-of-premature-ventricular-complex-burden-on-long-term-outcome
#20
Chin-Yu Lin, Shih-Lin Chang, Yenn-Jiang Lin, Yun-Yu Chen, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tze-Fan Chao, Fa-Po Chung, Jo-Nan Liao, Yao-Ting Chang, Chung-Hsing Lin, Rohit Walia, Abigail Louise D Te, Shinya Yamada, Chuen-Wang Chiou, Hsuan-Ming Tsao, Shih-Ann Chen
The long-term clinical impact of premature ventricular complexes (PVCs) on mortality and morbidity has not been fully studied. This study aimed to investigate the association between the burden of PVCs and adverse clinical outcome.A total of 5778 subjects, who were pacemaker-free and ventricular tachycardia-free at baseline, received 24-hour electrocardiography monitoring between January 1, 2002 and December 31, 2004. Clinical event data were retrieved from the Bureau of National Health Insurance of Taiwan...
January 2017: Medicine (Baltimore)
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