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https://www.readbyqxmd.com/read/28829571/bio-inspired-programmable-polymer-gel-controlled-by-swellable-guest-medium
#1
Heng Deng, Yuan Dong, Jheng-Wun Su, Cheng Zhang, Yunchao Xie, Chi Zhang, Matthew R Maschmann, Yuyi Lin, Jian Lin
Responsive materials with functions of forming three-dimensional (3D) origami and/or kirigami structures have a broad range of applications in bioelectronics, metamaterials, microrobotics, and microelectromechanical (MEMS) systems. To realize such functions, building blocks of actuating components usually possess localized inhomogeneous so that they respond differently to external stimuli. Previous fabrication strategies lie in localizing non-swellable or less-swellable guest components in their swellable host polymers to reduce swelling ability...
August 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28829384/self-sealing-cementitious-materials-by-using-water-swelling-rubber-particles
#2
Leyang Lv, Erik Schlangen, Feng Xing
Water ingress into cracked concrete structures is a serious problem, as it can cause leakage and reinforcement corrosion and thus reduce functionality and safety of the structures. In this study, the application of water-swelling rubber particles for providing the cracked concrete a self-sealing function was developed. The feasibility of applying water-swelling rubber particles and the influence of incorporating water-swelling rubber particles on the mechanical properties of concrete was investigated. The self-sealing efficiency of water-swelling rubber particles with different content and particle size was quantified through a permeability test...
August 22, 2017: Materials
https://www.readbyqxmd.com/read/28828853/activation-of-actuating-hydrogels-with-ws2-nanosheets-for-biomimetic-cellular-structures-and-steerable-prompt-deformation
#3
Lu Zong, Mingjie Li, Jun You, Xiaochen Wu, Chaoxu Li
Macroscopic soft actuation is intrinsic to living organisms in nature, including slow deformation (e.g. contraction, bending, twisting and curling) of plants motivated by microscopic swelling/shrinking of cells, and rapid motion of animals (e.g. deformation of jellyfish) motivated by cooperative nanoscale movement of motor proteins. These actuation behaviours, with exceptional combination of tuneable speed and programmable deformation direction, inspire to design artificial soft actuators for broad applications in artificial muscles, nanofabrication, chemical valve, microlenses, soft robotics etc...
August 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28828769/myxoid-liposarcoma-originating-in-the-anterior-mediastinum
#4
Mohammad Harisullah Khan, Ramsha Kashif, Hamza Abdur Rahim Khan, Saulat Hasnain Fatimi
Myxoid liposarcomas of the head and neck are mostly metastatic in nature, with the primary lesion usually in lower extremities or retroperitoneum. Primary mediastinal liposarcomas are even rarer. Although there have been previous cases reporting their incidence, there is no evidence of any case comprising of both the neck and the mediastinal region yet. We here present a case of a 43 year old male with a primary liposarcoma of the myxoid subtype originating in the anterior mediastinum. This is the first time such a case has presented in literature...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28828605/taurine-homeostasis-and-volume-control
#5
Herminia Pasantes-Morales
Taurine content is high (mM) in mammalian brain. By its major role as an osmolyte, taurine contributes to the cell volume control, which is particularly critical in the brain. Taurine participates in osmotic adjustments required to maintain the organization and size of intracellular compartments. It counteracts volume fluctuations in unbalanced transmembrane fluxes of ions and neurotransmitters, preserving the functional synaptic contacts. Taurine has a key role in the long-term adaptation to chronic hyponatremia as well as in other pathologies leading to brain edema...
2017: Advances in Neurobiology
https://www.readbyqxmd.com/read/28828450/nanoporous-amorphous-ge-si-alloys-unraveling-the-physics-behind-ion-beam-induced-morphogenesis
#6
Fritz Lehnert, Stefan G Mayr
Despite a high technical relevance and 35 years of observation, self-organized morphogenesis of nanoporous sponge-like amorphous structures during exposure of selected covalent materials to energetic ions is still insufficiently understood. Due to the presence and absence of these effects in amorphous Ge and Si, respectively, the Ge-Si alloy system constitutes an ideal testbed to track down the underlying physics at the atomic scale. This is realized within the present study by a combination of tailored experiments and extensive molecular dynamics computer modeling...
August 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28828153/effect-of-polyethelene-oxide-on-the-thermal-degradation-of-cellulose-biofilm-low-cost-material-for-soft-tissue-repair-in-dentistry
#7
Anna Akkus, Rakim Tyler, David Schiraldi, Renato Roperto, Fady Faddoul, Sorin Teich
BACKGROUND: Bio cellulose is a byproduct of sweet tea fermentation known as kombusha. During the biosynthesis by bacteria cellulose chains are polymerized by enzyme from activated glucose. The single chains are then extruded through the bacterial cell wall. Interestingly, a potential of the Kombucha's byproduct bio cellulose (BC) as biomaterial had come into focus only in the past few decades. The unique physical and mechanical properties such as high purity, an ultrafine and highly crystalline network structure, a superior mechanical strength, flexibility, pronounced permeability to gases and liquids, and an excellent compatibility with living tissue that reinforced by biodegradability, biocompatibility, large swelling ratios...
July 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28827916/ring-finger-necrosis-due-to-a-ring
#8
B A Ramesh, J Satish Kumar
Crush injury to finger is one of the common traumas in clinical practice. The injured patients often have a ring on their finger. The ring can be removed by non-operative techniques or by cutting the ring off and thus avoiding any long-term consequences. If the ring is not removed, the finger may swell and gangrene could occur. We present an unusual case of gangrene terminal finger due to a ring. The gangrene of this type is rarely reported in literature. The case is presented to stress the importance of removal of any circumferential foreign body on limbs before surgery...
August 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28827852/adverse-effects-of-antiepileptic-drug-lamotrigine-and-oral-implications-case-report
#9
Ana Ivanišević Malčić, Đurđica Sivić, Jurica Matijević
Here, we report on a patient who presented with extensive oral lesions. The treatment with lamotrigine is described.The patient presented with bilateral facial swellings and mental space swelling with actively draining extra oral sinus tract in the central chin area. Dental medicine professionals should be aware of the risks involved with using this medication, and should recognize the population at risk among patients suffering from epilepsy, bipolar and neurologic disorders.
June 2017: Acta Stomatologica Croatica
https://www.readbyqxmd.com/read/28827204/evaluation-of-different-crosslinking-agents-on-hybrid-biomimetic-collagen-hydroxyapatite-composites-for-regenerative-medicine
#10
Gopal Shankar Krishnakumar, Natalia Gostynska, Massimiliano Dapporto, Elisabetta Campodoni, Monica Montesi, Silvia Panseri, Anna Tampieri, Elizaveta Kon, Maurilio Marcacci, Simone Sprio, Monica Sandri
This study focuses on the development of novel bone-like scaffolds by bio-inspired, pH-driven, mineralization of type I collagen matrix with magnesium-doped hydroxyapatite nanophase (MgHA/Coll). To this aim, this study evaluates the altered modifications in the obtained composite due to different crosslinkers such as dehydrothermal treatment (DHT), 1,4-butanediol diglycidyl ether (BDDGE) and ribose in terms of morphological, physical-chemical and biological properties. The physical-chemical properties of the composites evaluated by XRD, FTIR, ICP and TGA demonstrated that the chemical mimesis of bone was effectively achieved using the in-lab biomineralization process...
August 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28826838/interferon-%C3%AE-driven-inos-a-molecular-pathway-to-terminal-shock-in-arenavirus-hemorrhagic-fever
#11
Melissa M Remy, Mehmet Sahin, Lukas Flatz, Tommy Regen, Lifen Xu, Mario Kreutzfeldt, Benedict Fallet, Camille Doras, Toni Rieger, Lukas Bestmann, Uwe-Karsten Hanisch, Beat A Kaufmann, Doron Merkler, Daniel D Pinschewer
Arenaviruses such as Lassa virus (LASV) cause hemorrhagic fever. Terminal shock is associated with a systemic cytokine storm, but the mechanisms are ill defined. Here we used HLA-A2-expressing mice infected with a monkey-pathogenic strain of lymphocytic choriomeningitis virus (LCMV-WE), a close relative of LASV, to investigate the pathophysiology of arenavirus hemorrhagic fever (AHF). AHF manifested as pleural effusions, edematous skin swelling, and serum albumin loss, culminating in hypovolemic shock. A characteristic cytokine storm included numerous pro-inflammatory cytokines and nitric oxide (NO) metabolites...
August 14, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28826781/clitoria-ternatea-flower-petals-effect-on-tnfr1-neutralization-via-downregulation-of-synovial-matrix-metalloproteases
#12
Rana Adhikary, Sahin Sultana, Biswadev Bishayi
ETHNOPHARMACOLOGICAL RELEVANCE: Clitoria ternatea Linn. (C. ternatea) is a traditionally used herb in arthritis, and its anti-arthritic activity has been attributed to polyphenols (e.g. quercetins) from its flower petal. AIM OF THE STUDY: The present study was designed to investigate whether C. ternatea or quercetin-3ß-D-glucoside (QG) support the antibody mediated TNFα-receptor 1 (TNFR1) neutralization to ameliorate arthritis in mice. MATERIALS AND METHODS: Development of collagen-induced arthritis (CIA) in male Swiss mice (20-22g, 3-4 weeks of age) was followed by estimation of synovial polymorphonuclear cell (PMN) accumulation (in terms of myeloperoxidase activity), synovial and systemic release of cytokines, chemokines and C-reactive protein (CRP) by enzyme-linked immunosorbent assay (ELISA), biochemical estimation of synovial free radical generation and antioxidant status, as well as immunoblot assessment of synovial TNFR1, toll-like receptor 2(TLR2), cyclooxygenase-2(COX-2) and inducible nitric oxide synthase (iNOS) expression; and zymographic analysis of synovial matrix-metalloprotease-2 (MMP-2) activity...
August 18, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28823104/novel-polymeric-composites-based-on-carboxymethyl-chitosan-and-poly-acrylic-acid-in-vitro-and-in-vivo-evaluation
#13
Qurat-Ul-Ain Sharif, Muhammad Sohail, Mahmood Ahmad, Muhammad Usman Minhas, Shahzeb Khan, Samiullah Khan, Mubeen Kousar
The purpose of the study was to develop a novel, efficient, stable, chemically crosslinked polymeric system that have pH responsive behaviour and can effectively release 5-FU in a controlled manner. Furthermore it can target colonic cancer minimizing the side effects of in vivo chemotherapy via 5-FU. Swelling and drug release studies were performed to evaluate its in vitro release behaviour. Hydrogels were also characterized by FTIR, SEM and DSC. In vitro cytocompatibility and cytotoxicity of the hydrogels were determined by MTT assay using HeLa cells...
August 19, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28822792/imaging-assessment-of-fibrodysplasia-ossificans-progressiva-qualitative-quantitative-and-questionable
#14
Mona Al Mukaddam, Chamith S Rajapakse, Robert J Pignolo, Frederick S Kaplan, Stacy E Smith
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare autosomal dominant genetic disorder of heterotopic ossification (HO) characterized by skeletal anomalies and episodic soft tissue swelling (flare-ups) that can transform into heterotopic bone. The progressive development of heterotopic bone and progressive arthropathy leads to significant limitation of mobility. This paper will review various imaging modalities used in evaluating episodic soft tissue swelling (flare-ups), heterotopic bone and skeletal anomalies...
August 16, 2017: Bone
https://www.readbyqxmd.com/read/28822312/ossifying-fibromyxoid-tumor-of-the-trunk-mimicking-hydatid-cyst-a-case-report
#15
Nihed Abdessayed, Sarra Mestiri, Houssem Ammar, Ahlem Bdioui, Amine Chhaidar, Omar Toumi, Nozha Mhamdi, Rahul Gupta, Marwa Guerfela, Moncef Mokni
INTRODUCTION: Ossifying fibromyxoid tumor (OFMT) is a rare lesion that generally occurs in the soft tissues of proximal limbs, head or neck and presents as a slowly growing mass. Abdominal or trunk locations are extremely rare. PRESENTATION OF CASE: We report a case of 50-year-old man who presented with a painless, slow growing epigastric mass for 5 years. Radiologic assessment revealed a well circumscribed median subcutaneous parietal mass lesion present in front of the xiphoid process suspicious of a calcified hydatid cyst...
July 22, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28821624/a-sweet-case-of-mycoplasma
#16
Jackie Hsieh, Ali Yalcindag, Daniel T Coghlin
Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is an uncommon inflammatory disorder marked by fever and swelling of the skin that can be very painful. It is especially rare in the pediatric population. Infection is a well-known trigger for Sweet syndrome, but this entity has, to our knowledge, never been described after Mycoplasma infection. Herein, we describe the first pediatric case of febrile neutrophilic dermatosis associated with Mycoplasma infection.
August 18, 2017: Pediatrics
https://www.readbyqxmd.com/read/28821342/dexamethasone-seems-to-reduce-pain-swelling-and-mouth-opening-reduction-compared-with-diclofenac-after-third-molar-extraction
#17
Romina Brignardello-Petersen
No abstract text is available yet for this article.
August 11, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28821147/uv-crosslinkable-and-thermo-responsive-chitosan-hybrid-hydrogel-for-nir-triggered-localized-on-demand-drug-delivery
#18
Lei Wang, Baoqiang Li, Feng Xu, Zheheng Xu, Daqing Wei, Yujie Feng, Yaming Wang, Dechang Jia, Yu Zhou
Innovative drug delivery technologies based on smart hydrogels for localized on-demand drug delivery had aroused great interest. To acquire smart UV-crosslinkable chitosan hydrogel for NIR-triggered localized on-demanded drug release, a novel UV-crosslinkable and thermo-responsive chitosan was first designed and synthesized by grafting with poly N-isopropylacrylamide, acetylation of methacryloyl groups and embedding with photothermal carbon. The UV-crosslinkable unit (methacryloyl groups) endowed chitosan with gelation via UV irradiation...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821146/evaluation-of-carboxymethyl-moringa-gum-as-nanometric-carrier
#19
Rimpy, Abhishek, Munish Ahuja
In the present study, carboxymethylation of Moringa oleifera gum was carried out by reacting with monochloroacetic acid. Modified gum was characterised employing Fourier-transform infrared spectroscopy, differential scanning calorimetry, X-ray diffraction, scanning electron microscopy, and Rheology study. The carboxymethyl modification of moringa gum was found to increase its degree of crystallinity, reduce viscosity and swelling, increase the surface roughness and render its more anionic. The interaction between carboxymethyl moringa gum and chitosan was optimised by 2-factor, 3-level central composite experimental design to prepare polyelectrolyte nanoparticle using ofloxacin, as a model drug...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821138/biocompatible-chitin-carbon-nanotubes-composite-hydrogels-as-neuronal-growth-substrates
#20
Shuangquan Wu, Bo Duan, Ang Lu, Yanfeng Wang, Qifa Ye, Lina Zhang
In the past decades, extensive studies have demonstrated that carbon nanotubes (CNTs) could promote cell adhesion, proliferation and differentiation of neuronal cells. However, the potential cytotoxicity in biological systems severely restricted the utilization of CNTs as substrates for neural growth. In this study, biocompatible chitin/carbon nanotubes (Ch/CNT) composite hydrogels were developed via blending modified CNTs with chitin solution in 11wt% NaOH/4wt% urea aqueous system, and subsequently regenerating in ethanol...
October 15, 2017: Carbohydrate Polymers
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