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https://www.readbyqxmd.com/read/28634179/lessons-from-bacterial-homolog-of-tubulin-ftsz-for-microtubule-dynamics
#1
Rachana Rao Battaje, Dulal Panda
FtsZ, a homolog of tubulin, is found in almost all bacteria and archaea where it has a primary role in cytokinesis. Evidence for structural homology between FtsZ and tubulin came from their crystal structures and identification of the GTP-box. Tubulin and FtsZ constitute a distinct family of GTPases and show striking similarities in many of their polymerization properties. The differences between them, more so, the complexities of microtubule dynamic behavior in comparison to that of FtsZ, indicate that the evolution to tubulin is attributable to the incorporation of the complex functionalities in higher organisms...
June 20, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/28632417/detection-and-antigenic-profiling-of-undeclared-peanut-in-imported-garlic-using-an-xmap-multiplex-immunoassay-for-food-allergens
#2
Ronnie O Pedersen, Tim Peters, Rakhi Panda, Paul Wehling, Eric A E Garber
A shipment of imported garlic powder was suspected of containing peanut. Samples (subs) collected from the shipment displayed considerable variability in peanut antigenicity when analyzed by enzyme-linked immunosorbent assay (ELISA). This raised questions regarding whether peanut was actually present, the amount present, and the basis for the variability in antigenic content. Analyses that used an xMAP multiplex assay for the detection of peanut and additional food allergens generated responses that were characteristic of peanut...
June 20, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28630944/clinvar-data-parsing
#3
Xiaolei Zhang, Eric V Minikel, Anne H O'Donnell-Luria, Daniel G MacArthur, James S Ware, Ben Weisburd
This software repository provides a pipeline for converting raw ClinVar data files into analysis-friendly tab-delimited tables, and also provides these tables for the most recent ClinVar release. Separate tables are generated for genome builds GRCh37 and GRCh38 as well as for mono-allelic variants and complex multi-allelic variants. Additionally, the tables are augmented with allele frequencies from the ExAC and gnomAD datasets as these are often consulted when analyzing ClinVar variants. Overall, this work provides ClinVar data in a format that is easier to work with and can be directly loaded into a variety of popular analysis tools such as R, python pandas, and SQL databases...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/28630711/matchmaker-com-for-pandas
#4
Bridie J M Allan
No abstract text is available yet for this article.
2017: Conservation Physiology
https://www.readbyqxmd.com/read/28622675/state-of-the-art-methods-for-brain-tissue-segmentation-a-review
#5
Lingraj Dora, Sanjay Agrawal, Rutuparna Panda, Ajith Abraham
Brain tissue segmentation is one of the most sought after research area in medical image processing. It provides detailed quantitative brain analysis for accurate disease diagnosis, detection and classification of abnormalities. It plays an essential role in discriminating healthy tissues from lesion tissues. Therefore, accurate disease diagnosis and treatment planning depends merely on the performance of segmentation method used. In this paper, we have studied the recent advances in brain tissue segmentation methods and their state-of-the-art in neuroscience research...
June 14, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28621268/assessment-of-oral-hygiene-knowledge-practices-and-concepts-of-tobacco-usage-among-engineering-students-in-bhubaneswar-odisha-india
#6
Alokenath Bandyopadhyay, Lipsa Bhuyan, Abikshyeet Panda, Kailash C Dash, Malvika Raghuvanshi, Shyam S Behura
AIM: This study aimed to assess oral hygiene-related knowledge and practices among engineering students of Bhubaneswar city and also to evaluate the concepts about the side effects of tobacco usage among those students. MATERIALS AND METHODS: The study was conducted using a self-administered, close-ended questionnaire to assess the oral hygiene knowledge and practices and study the concepts on tobacco usage among 362 engineering students of Bhubaneswar city, Odisha, India...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28620224/comparing-the-plant-diversity-between-artificial-forest-and-nature-growth-forest-in-a-giant-panda-habitat
#7
Dongwei Kang, Xiaorong Wang, Shuang Li, Junqing Li
Artificial restoration is an important way to restore forests, but little is known about its effect on the habitat restoration of the giant panda. In the present study, we investigated the characteristics of artificial forest in the Wanglang Nature Reserve to determine whether through succession it has formed a suitable habitat for the giant panda. We compared artificial forest characteristics with those of natural habitat used by the giant panda. We found that the dominant tree species in artificial forest differed from those in the natural habitat...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28616195/assessing-vulnerability-of-giant-pandas-to-climate-change-in-the-qinling-mountains-of-china
#8
Jia Li, Fang Liu, Yadong Xue, Yu Zhang, Diqiang Li
Climate change might pose an additional threat to the already vulnerable giant panda (Ailuropoda melanoleuca). Effective conservation efforts require projections of vulnerability of the giant panda in facing climate change and proactive strategies to reduce emerging climate-related threats. We used the maximum entropy model to assess the vulnerability of giant panda to climate change in the Qinling Mountains of China. The results of modeling included the following findings: (1) the area of suitable habitat for giant pandas was projected to decrease by 281 km(2) from climate change by the 2050s; (2) the mean elevation of suitable habitat of giant panda was predicted to shift 30 m higher due to climate change over this period; (3) the network of nature reserves protect 61...
June 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28615914/piloerection-a-rare-ictal-phenomenon-case-report-and-review-of-literature
#9
Samhita Panda, Chandrashekhar Agarwal, Ankkita Sharma
No abstract text is available yet for this article.
April 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28615713/exosomal-micrornas-in-giant-panda-ailuropoda-melanoleuca-breast-milk-potential-maternal-regulators-for-the-development-of-newborn-cubs
#10
Jideng Ma, Chengdong Wang, Keren Long, Hemin Zhang, Jinwei Zhang, Long Jin, Qianzi Tang, Anan Jiang, Xun Wang, Shilin Tian, Li Chen, Dafang He, Desheng Li, Shan Huang, Zhi Jiang, Mingzhou Li
The physiological role of miRNAs is widely understood to include fine-tuning the post-transcriptional regulation of a wide array of biological processes. Extensive studies have indicated that exosomal miRNAs in the bodily fluids of various organisms can be transferred between living cells for the delivery of gene silencing signals. Here, we illustrated the expression characteristics of exosomal miRNAs in giant panda breast milk during distinct lactation periods and highlighted the enrichment of immune- and development-related endogenous miRNAs in colostral and mature giant panda milk...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28614359/phenological-changes-in-bamboo-carbohydrates-explain-the-preference-for-culm-over-leaves-by-giant-pandas-ailuropoda-melanoleuca-during-spring
#11
Katrina K Knott, Amelia L Christian, Josephine F Falcone, Carrie K Vance, Laura L Bauer, George C Fahey, Andrew J Kouba
Seasonal changes in the foodscape force herbivores to select different plant species or plant parts to meet nutritional requirements. We examined whether the search for calorie-rich carbohydrates explained giant panda's selection for bamboo culm over leaves during spring. Leaves and culms were collected from four Phyllostachys bamboos (P. aurea, P. aureosulcata, P. glauca, and P. nuda) once per month over 18-27 months. Monthly changes in annual plant part nutrients were examined, and compared to seasonal foraging behaviors of captive giant pandas...
2017: PloS One
https://www.readbyqxmd.com/read/28611401/a-diet-diverse-in-bamboo-parts-is-important-for-giant-panda-ailuropoda-melanoleuca-metabolism-and-health
#12
Hairui Wang, Heju Zhong, Rong Hou, James Ayala, Guangmang Liu, Shibin Yuan, Zheng Yan, Wenping Zhang, Yuliang Liu, Kailai Cai, Zhigang Cai, He Huang, Zhihe Zhang, De Wu
The aim of this study was to determine the metabolic response in giant pandas (Ailuropoda melanoleuca) to the consumption of certain parts of bamboo above ground growth. Giant pandas were provisioned with three species of bamboo: Phyllostachys bissetii, of which they only consume the culm (culm group); Bashania fargesii, of which they only consume the leaves (leaf group); and Qiongzhuea opienensis, of which they only consume the shoots (shoot group). The "culm" group absorbed the highest amount of calories and fiber, but was in short energy supply (depressed tricarboxylic acid cycle activity), and high fiber level diet might reduce the digestibility of protein...
June 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28604681/corrigendum-plant-cholesterol-biosynthetic-pathway-overlaps-with-phytosterol-metabolism
#13
Prashant D Sonawane, Jacob Pollier, Sayantan Panda, Jedrzej Szymanski, Hassan Massalha, Meital Yona, Tamar Unger, Sergey Malitsky, Philipp Arendt, Laurens Pauwels, Efrat Almekias-Siegl, Ilana Rogachev, Sagit Meir, Pablo D Cárdenas, Athar Masri, Marina Petrikov, Hubert Schaller, Arthur A Schaffer, Avinash Kamble, Ashok P Giri, Alain Goossens, Asaph Aharoni
This corrects the article DOI: 10.1038/nplants.2016.205.
June 12, 2017: Nature Plants
https://www.readbyqxmd.com/read/28601148/leptin-supplementation-in%C3%A2-vitro-improved-developmental-competence-of-buffalo-oocytes-and-embryos
#14
Bibhudatta S K Panda, Sriti Pandey, Anjali Somal, Mehtab S Parmar, Irfan A Bhat, Indu Baiju, Mukesh K Bharti, G Sai Kumar, Vikash Chandra, G Taru Sharma
The aim of the present study was to determine potential role of leptin on in vitro developmental competence of buffalo oocytes and embryos. Slaughterhouse derived culture grade buffalo cumulus oocyte complexes (COCs) were matured in vitro (IVM) with leptin (10 ng/ml) or without leptin (control). In each experiment, a pool of matured COCs was used for further in vitro embryo production and another pool of COCs was used for cumulus cells and mature oocytes isolation to study the relative mRNA expression of developmentally important genes...
August 2017: Theriogenology
https://www.readbyqxmd.com/read/28600164/mercury-based-drug-in-ancient-india-the-red-sulfide-of-mercury-rasasindur-in-nanoscale
#15
Priyabrata Mukhi, Swapna Sarita Mohapatra, M Bhattacharjee, K K Ray, T S Muraleedharan, A Arun, R Sathyavathi, R R Juluri, P V Satyam, Alok K Panda, Ashis Biswas, S Nayak, Sreedhar Bojja, S Pratihar, Sujit Roy
Mercury is one of the elements which had attracted the attention of the chemists and physicians of ancient India and China. Among the various metal based drugs which utilize mercury, we became interested in the red sulfide of mercury which is known in ancient Indian literature as rasasindur (alias rasasindura, rasasindoor, rasasinduram, sindur, or sindoor) and is used extensively in various ailments and diseases. Following various physico-chemical characterizations it is concluded that rasasindur is chemically pure α-HgS with Hg:S ratio as 1:1...
June 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28596990/magnetic-resonance-imaging-of-cerebral-malaria-patients-reveals-distinct-pathogenetic-processes-in-different-parts-of-the-brain
#16
Sanjib Mohanty, Laura A Benjamin, Megharay Majhi, Premanand Panda, Sam Kampondeni, Praveen K Sahu, Akshaya Mohanty, Kishore C Mahanta, Rajyabardhan Pattnaik, Rashmi R Mohanty, Sonia Joshi, Anita Mohanty, Ian W Turnbull, Arjen M Dondorp, Terrie E Taylor, Samuel C Wassmer
The mechanisms underlying the rapidly reversible brain swelling described in patients with cerebral malaria (CM) are unknown. Using a 1.5-Tesla (T) magnetic resonance imaging (MRI) scanner, we undertook an observational study in Rourkela, India, of 11 Indian patients hospitalized with CM and increased brain volume. Among the 11 cases, there were 5 adults and 6 children. All patients had reduced consciousness and various degrees of cortical swelling at baseline. The latter was predominately posterior in distribution...
May 2017: MSphere
https://www.readbyqxmd.com/read/28596647/audio-vestibular-status-in-cml-patients-on-imatinib-mesylate-with-review-of-literature
#17
Rijuneeta Gupta, Uday Yanamandra, Bhumika Gupta, Naresh K Panda, Subhash Varma, Anu Nagarkar, Pankaj Malhotra
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm occasionally presenting with features of leukostasis as primary symptoms. Hearing loss is occasionally reported in CML patients. Further whether Imatinib mesylate has any effect on vestibular functions is not known. We conducted a preliminary study to assess hearing pattern in patients with CML on long term TKI therapy. This is a single center, cross sectional study from northern-India. Patients of CML who were on regular Tyrosine kinase inhibitors (TKI) therapy for at least 6 months underwent audiovestibular evaluation ...
June 2017: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/28595495/lipid-based-nanoformulation-of-lycopene-improves-oral-delivery-formulation-optimization-ex-vivo-assessment-and-its-efficacy-against-breast-cancer
#18
Archu Singh, Yub Raj Neupane, Bibhu Prasad Panda, Kanchan Kohli
This study aims at developing an optimized Nanostructured Lipid Carrier (NLC) of Lycopene for efficient absorption following oral administration. The optimized formulation showed an average particle size of 121.9±3.66 nm, Poly dispersity index (PDI) 0.370±0.97 and zeta potential -29.0± 0.83 mV. Encapsulation Efficiency (% EE) and Drug Loading (% DL) was found to be 84.50% ± 4.38 and 9.54% ± 2.65 respectively. In vitro release studies demonstrated the burst release within 4-9 h followed by sustained release over 48 h...
June 9, 2017: Journal of Microencapsulation
https://www.readbyqxmd.com/read/28595453/chemical-composition-and-antioxidant-activities-of-the-essential-oil-of-hypericum-gaitii-haines-an-endemic-species-of-eastern-india
#19
Pradeep Kumar Kamila, Asit Ray, Sudipta Jena, Pradipta Kumar Mohapatra, Pratap Chandra Panda
The present study reports the chemical composition and antioxidant activities of the essential oil extracted from the leaves and tender branches of Hypericum gaitii Haines (Hypericaceae) - an endemic plant of Eastern India. On hydrodistillation, the fresh leaves and tender parts of H. gaitii yielded 0.43% (v/w) of pale yellowish essential oil. Gas chromatography mass spectrometry analysis revealed the presence of 40 compounds, which represent 96.9% of the total oil. Monoterpene hydrocarbons (79.3%) predominated followed by sesquiterpene hydrocarbons (12...
June 8, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28592334/impact-of-oocyte-secreted-factors-on-its-developmental-competence-in-buffalo
#20
Swati Gupta, Sriti Pandey, Mehtab S Parmar, Anjali Somal, Avishek Paul, Bibhudatta S K Panda, Irfan A Bhat, Indu Baiju, Mukesh K Bharti, G Saikumar, Mihir Sarkar, Vikash Chandra, G Taru Sharma
Oocyte-secreted factors (OSFs) play an important role in the acquisition of oocyte developmental competence through bidirectional cross-talk between oocyte and cumulus cells via gap junctions. Thus, the present study was designed to investigate the effect of two OSFs, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), on the developmental competence of buffalo oocytes derived from two different follicle sizes. Cumulus-oocyte complexes (COCs) from large follicles (LF, >6 mm) or small follicles (SF, 0...
June 8, 2017: Zygote: the Biology of Gametes and Early Embryos
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