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https://www.readbyqxmd.com/read/28531764/disrupted-resting-brain-graph-measures-in-individuals-at-high-risk-for-alcoholism
#1
Bharath Holla, Rajanikant Panda, Ganesan Venkatasubramanian, Bharat Biswal, Rose Dawn Bharath, Vivek Benegal
Familial susceptibility to alcoholism is likely to be linked to the externalizing diathesis seen in high-risk offspring from high-density alcohol use disorder (AUD) families. The present study aimed at comparing resting brain functional connectivity and their association with externalizing symptoms and alcoholism familial density in 40 substance-naive high-risk (HR) male offspring from high-density AUD families and 30 matched healthy low-risk (LR) males without a family history of substance dependence using graph theory-based network analysis...
May 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28529417/nasolabial-perforator-flap-for-one-stage-reconstruction-of-nasal-defects
#2
Siddharth Prakash, Ritesh Panda, Vivek Kumar, Shiv Shankar Saha, Lalit Choudhary, Anurag Pandey, J Sasidhar Reddy
BACKGROUND: The excellent freedom of movement and range of this flap when based on a the nasolabial perforator flap have not been sufficiently explored. In this study, along with demonstrating the other key advantages of this flap over its traditional counterpart, we will endeavour to fill these lacunae in the available literature. MATERIALS AND METHODS: From February 2009 to February 2012, twenty patients with nasal defects were repaired with a nasolabial perforator flap in the Department of Plastic and Cosmetic Surgery at Sir Ganga Ram Hospital, New Delhi...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28527166/consensus-on-initiation-and-intensification-of-premix-insulin-in-type-2-diabetes-management
#3
Viswanathan Mohan, Sanjay Kalra, Jothydev Kesavadev, Awadhesh Kumar Singh, Ajay Kumar, Ambika Gopalakrishnan Unnikrishnan, Rajeev Chawla, Jagat Jyoti Mukherjee, Rakesh Kumar Sahay, J S Kumar, Anil Bhoraskar, Arthur J Asirvatham, Jayanta Kumar Panda, Abdul Hamid Zargar, Ashok Kumar Das
INTRODUCTION: Premix insulin is the most commonly used insulin preparation in India. The first Indian premix guidelines were developed in 2009 and thereafter were updated in 2013. There is a need to revisit the Indian premix insulin guidelines, in view of emerging evidence and introduction of newer co-formulations. OBJECTIVE: The present consensus has been developed to evaluate available premix formulations, examine existing evidence related to premix formulations, and evolve consensus statement of recommendations on the topic...
April 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28524089/green-synthesized-zinc-oxide-zno-nanoparticles-induce-oxidative-stress-and-dna-damage-in-lathyrus-sativus-l-root-bioassay-system
#4
Kamal K Panda, Dambaru Golari, A Venugopal, V Mohan M Achary, Ganngam Phaomei, Narasimham L Parinandi, Hrushi K Sahu, Brahma B Panda
Zinc oxide nanoparticles (ZnONP-GS) were synthesised from the precursor zinc acetate (Zn(CH₃COO)₂) through the green route using the milky latex from milk weed (Calotropis gigantea L. R. Br) by alkaline precipitation. Formation of the ZnONP-GS was monitored by UV-visible spectroscopy followed by characterization and confirmation by energy-dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), and X-ray diffraction (XRD). Both the ZnONP-GS and the commercially available ZnONP-S (Sigma-Aldrich) and cationic Zn(2+) from Zn(CH₃COO)₂ were tested in a dose range of 0-100 mg·L(-1) for their potency (i) to induce oxidative stress as measured by the generation reactive oxygen species (ROS: O₂(•-), H₂O₂ and (•)OH), cell death, and lipid peroxidation; (ii) to modulate the activities of antioxidant enzymes: catalase (CAT), superoxide dismutase (SOD), guaiacol peroxidase (GPX), and ascorbate peroxidase (APX); and (iii) to cause DNA damage as determined by Comet assay in Lathyrus sativus L...
May 18, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28516920/china-rail-network-must-protect-giant-pandas
#5
Shucai Li, Shaoshuai Shi, Lin Bu
No abstract text is available yet for this article.
May 17, 2017: Nature
https://www.readbyqxmd.com/read/28516123/polysome-fractionation-to-analyze-mrna-distribution-profiles
#6
Amaresh C Panda, Jennifer L Martindale, Myriam Gorospe
Eukaryotic cells adapt to changes in external or internal signals by precisely modulating the expression of specific gene products. The expression of protein-coding genes is controlled at the transcriptional and post-transcriptional levels. Among the latter steps, the regulation of translation is particularly important in cellular processes that require rapid changes in protein expression patterns. The translational efficiency of mRNAs is altered by RNA-binding proteins (RBPs) and noncoding (nc)RNAs such as microRNAs (Panda et al...
February 5, 2017: Bio-protocol
https://www.readbyqxmd.com/read/28516119/affinity-pulldown-of-biotinylated-rna-for-detection-of-protein-rna-complexes
#7
Amaresh C Panda, Jennifer L Martindale, Myriam Gorospe
RNA-binding proteins (RBPs) have recently emerged as crucial players in the regulation of gene expression. The interactions of RBPs with target mRNAs control the levels of gene products by altering different regulatory steps, including pre-mRNA splicing and maturation, nuclear mRNA export, and mRNA stability and translation (Glisovic et al., 2008). There are several methodologies available today to identify RNAs bound to specific RBPs; some detect only recombinant molecules in vitro, others detect recombinant and endogenous molecules, while others detect only endogenous molecules...
December 20, 2016: Bio-protocol
https://www.readbyqxmd.com/read/28516066/the-alpha-tocopherol-form-of-vitamin-e-boosts-elastase-activity-of-human-pmns-and-their-ability-to-kill-streptococcus-pneumoniae
#8
Elsa N Bou Ghanem, James N Lee, Basma H Joma, Simin N Meydani, John M Leong, Alexander Panda
Despite the availability of vaccines, Streptococcus pneumoniae remains a leading cause of life-threatening infections, such as pneumonia, bacteremia and meningitis. Polymorphonuclear leukocytes (PMNs) are a key determinant of disease course, because optimal host defense requires an initial robust pulmonary PMN response to control bacterial numbers followed by modulation of this response later in infection. The elderly, who manifest a general decline in immune function and higher basal levels of inflammation, are at increased risk of developing pneumococcal pneumonia...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28512274/glucose-transporter-1-expression-in-odontogenic-keratocyst-dentigerous-cyst-and-ameloblastoma-an-immunohistochemical-study
#9
Alokenath Bandyopadhyay, Abikshyeet Panda, Shyam S Behura, Sujatha Ramachandra, Kailash C Dash, Pallavi Mishra
INTRODUCTION: An array of odontogenic lesions manifest in the maxillofacial region with variable presentations. The biological behavior of lesions, such as odontogenic keratocyst (OKC), dentigerous cyst (DC), and ameloblastoma (AM) always invite debate. Glucose transporter 1 (GLUT-1) is proven to be an indicator of metabolic behavior of several benign and malignant neoplasms. AIM: The purpose of this study was to evaluate the expression of GLUT-1 in OKC, DC, and AM to understand their metabolic behavior...
May 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28511393/utility-of-tru-cut-biopsy-of-breast-lesions-an-experience-in-a-regional-cancer-center-of-a-developing-country
#10
Sagarika Samantaray, Niharika Panda, Kusumabati Besra, Lucy Pattanayak, Subrat Samantara, Sashibhusan Dash
INTRODUCTION: Tru-cut Needle Biopsy (TCB) is an integral part of triple assessment of breast cancer, which includes clinical assessment, mammography and TCB or Core Needle Biopsy (CNB). The technique is reliable, simple, and reproducible, and inexpensive, which can be adapted even for low-income group of patients and in developing countries. AIM: This study was done to establish the efficacy of TCB of palpable breast lesions in a developing country where mammography is not possible in all cases...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508743/mycobacterium-kansasii-isolated-from-tuberculinpositive-rhesus-macaques-macaca-mulatta-in-the-absence-of-disease
#11
Steven T Shipley, David K Johnson, Morteza Roodgar, David Glenn Smith, Charles A Montgomery, Steven M Lloyd, James A Higgins, Edwin H Kriel, Hilton J Klein, William P Porter, Jerome B Nazareno, Paul W Houghton, Aruna Panda, Louis J DeTolla
Mycobacterial infections are of primary health concern in NHP colonies in biomedical research. NHP are constantly monitoredand screened for Mycobacterium spp. We report 6 Chinese-origin rhesus macaques infected with Mycobacterium kansasii thatexhibited positive tuberculin skin tests in the absence of disease. Two of these macaques were being used for research purposes;the remaining 4 macaques were residing at the contract quarantine company. Histopathology and acid-fast staining of fixed tissues from all macaques showed that all were free of disease...
May 15, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28508671/chemometric-profile-antioxidant-and-tyrosinase-inhibitory-activity-of-camel-s-foot-creeper-leaves-bauhinia-vahlii
#12
Pritipadma Panda, Priyanka Dash, Goutam Ghosh
The present study is the first effort to a comprehensive evaluation of antityrosinase activity and chemometric analysis of Bauhinia vahlii. The experimental results revealed that the methanol extract of Bauhinia vahlii (BVM) possesses higher polyphenolic compounds and total antioxidant activity than those reported elsewhere for other more conventionally and geographically different varieties. The BVM contain saturated fatty acids such as hexadecanoic acid (10.15%), octadecanoic acid (1.97%), oleic acid (0.61%) and cis-vaccenic acid (2...
May 16, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28507408/effect-of-dietary-supplementation-of-fermented-fish-silage-on-serum-biochemical-parameters-of-broiler-japanese-quails-coturnix-coturnix-japonica
#13
Sasmita Panda, Laxman Kumar Babu, Arun Kumar Panda, Tanuja S, Anurag Mohanty, Kuldeep Kumar Panigrahy, Pinaki Samal
AIM: The objective of this study was to evaluate the effect of feeding fermented fish silage (FFS) on serum biochemical parameters of Japanese quails (Coturnix coturnix japonica). MATERIALS AND METHODS: A total of 192, 7-day-old broiler Japanese quail chicks of either sex, were randomly distributed into four dietary treatments with four replicates in each group having 12 chicks in each replicate pen. The dietary treatments were T1 - Control diet, T2 - Diet containing 5% FFS, T3 - Diet containing 10% FFS, and T4 - Diet containing 15% FFS...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28505448/spectroscopic-and-calorimetric-studies-of-molecular-recognitions-in-a-dendrimer-surfactant-complex
#14
Somnath Koley, Manas Ranjan Panda, Kiran Bharadwaj, Subhadip Ghosh
Molecular recognitions, causing supramolecular complex formation between a hyperbranched polymer molecule (PAMAM dendrimer generation 3) with oppositely charged surfactant sodium dodecyl sulfate (SDS) in aqueous solution, were studied by using various spectroscopic techniques and calorimetric titration of heat change measurements. Spectroscopic measurements were performed using dynamic Stokes shift (DSS), rotational anisotropy decay and translational diffusion of a fluorescent probe molecule coumarin 153 (C153) non-covalently attached to the dendrimer-surfactant complex...
May 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28502821/sasp-regulation-by-noncoding-rna
#15
REVIEW
Amaresh C Panda, Kotb Abdelmohsen, Myriam Gorospe
Noncoding RNAs (ncRNAs), including micro (mi)RNAs, long noncoding (lnc)RNAs, and circular (circ)RNAs, control specific gene expression programs by regulating transcriptional, post-transcriptional, and post-translational processes. Through their broad influence on protein expression and function, ncRNAs have been implicated in virtually all cellular processes such as proliferation, senescence, quiescence, differentiation, apoptosis, and the stress and immune responses. Senescence is a cellular phenotype associated with the physiologic decline of aging and with age-related pathologies...
May 11, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28498087/an-expert-opinion-on-pandas-pans-highlights-and-controversies
#16
Francesca Chiarello, Silvia Spitoni, Eric Hollander, Marco Matucci Cerinic, Stefano Pallanti
OBJECTIVES: 'Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections' (PANDAS) identified a unique subgroup of patients with abrupt onset of obsessive compulsive disorder (OCD) symptoms clinically related to Streptococcus infection and accompanied by neuropsychological and motor symptoms. After almost 20 years, PANDAS has not been accepted as distinct disorder and new criteria for paediatric acute-onset neuropsychiatric syndrome (PANS) have been replaced it, highlighting the fact that several agents rather than only Streptococcus might be involved...
February 13, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28493433/highly-active-and-iso-selective-catalysts-for-rop-of-cyclic-esters-using-group-2-metal-initiators
#17
Tarun Kanti Panda, Jayeeta Bhattacharjee, A Harinath, Hari P Nayek, Alok Sarkar
A series of alkali and alkaline earth (Ae) metal complexes bearing 1,2 phenylene(bis-diphenylphosphinothioic/selenoic amide) [{Ph2P(E)NH}2C6H4] (E = S (1-H2); Se (2-H2) ligands are reported. Alkali metal complexes [{Ph2P(S)N}2C6H4]Na(THF)4 (3a) [{Ph2P(Se)N}2C6H4]Na(THF)4 (3b), and [{Ph2P(Se)N}2C6H4]K(THF)5 (4b) were obtained in good yield by treating protic ligand 1-H2 or 2-H2 with corresponding metal hexamethyldisilazides [MN(SiMe3)2] (M = Na and K) at ambient temperature. The Ae metal complexes formulated as [{Ph2P(E)N}2C6H4]M(THF)3 [E = S, M = Ca (5a), Sr (6a), Ba (7a); E = Se, M = Ca (5b), Sr (6b), Ba (7b)] can be synthesized using two routes...
May 11, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28487507/transcriptional-regulation-of-foxp3-requires-integrated-activation-of-both-promoter-and-cns-regions-in-tumor-induced-cd8-treg-cells
#18
Sreeparna Chakraborty, Abir K Panda, Sayantan Bose, Dia Roy, Kirti Kajal, Deblina Guha, Gaurisankar Sa
T-regulatory cells are an upsurge in the tumor microenvironment and induce immune-evasion. CD4(+) Treg cells are well characterized whereas the role of CD8(+) Tregs in cancer has recently started to crease attention. Here, we report an augmentation CD8(+)FOXP3(+) Tregs in breast tumor microenvironment. FOXP3, the lineage-specific transcription factor, is a dominant regulator of Treg cell development and function. FOXP3 is induced preferentially by divergent signaling in CD4(+) Treg cells. But how FOXP3 is induced and maintained in tumor-CD8(+) Tregs is the Cinderella of the investigation...
May 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28481636/the-population-structure-and-genetic-divergence-of-labeo-gonius-hamilton-1822-analyzed-through-mitochondrial-dna-cytochrome-b-gene-for-conservation-in-indian-waters
#19
Bijay Kumar Behera, Vishwamitra Singh Baisvar, Ajaya Kumar Rout, Sudip Pakrashi, Kavita Kumari, Debabrata Panda, Pronob Das, Pranaya Kumar Parida, Dharmendra Kumar Meena, D Bhakta, Basanta Kumar Das, Joykrushna Jena
The present study explains the population structure and genetic diversity of medium carp Labeo gonius by analyzing partial sequence of mitochondrial DNA cytochrome b gene. Labeo gonius is a lower risk Near Threatened species, distributed throughout the North Indian major rivers, reservoirs and lakes. This species has a larger scope as an alternative candidate species in carp aquaculture system. In the present investigation, 223 individuals of Labeo gonius were collected from five locations of phylo-geographically isolated riverine ecosystems of India resulted in 12 haplotypes...
May 8, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28472439/panda-sign-sarcoidosis
#20
Hiroki Matsuura, Yasufumi Yamaji
No abstract text is available yet for this article.
May 3, 2017: QJM: Monthly Journal of the Association of Physicians
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